Senior principal scientist jobs in Andover, MA

Job Title: Scientist I Duration: 24 months, possibility to convert HM Notes: COVID VAX IS REQUIRED PRIOR TO STARTING! Fully onsite. Start ASAP. Two-year assignment with possibility to convert... Must have cloning exp. 0-3 years. PhD required (degree in or related to molecular bio, bio chem, micro bio, etc.) Experience can be from school, does not need to be industry. Not opposed to someone with more than 3 years experience... Day in the life: plasmid production, generate plasmids for pipelines, doing QC, in the future they will be automating the process so if they have automation exp that would be fantastic if not, okay, in lab 75% of day... Must Haves: Cloning Experience, Gibson assembly and Golden Gate assembly experience.... Like to have: Automation experience (they will be moving into automation so it would be great if the person was familiar with that but if not, they can be trained) Description: The Cell Line Development Department at is seeking a highly motivated Molecular Biology Scientist to join a high-performing, collaborative team focused on optimizing CHO cell line development platforms through advanced molecular biology techniques and automation. Responsibilities will focus on improving process workflows, expression system components, and CLD methods used to generate recombinant CHO cell lines for production of protein biologics. This will include the design and generation of next generation vector topologies utilizing modern cloning strategies such as Gibson assembly and Golden Gate cloning. The ideal candidate will possess expertise in high-throughput molecular biology workflows and automated vector construction pipelines. Work will directly support development projects in pipeline and will include frequent cross-functional interactions with colleagues in global CMC sites (US, France). Key Responsibilities • Design and construct expression vectors using advanced molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction enzyme-based cloning, and site-directed mutagenesis • Develop, optimize, and implement automated workflows for high-throughput vector construction and DNA assembly on liquid handling platforms • Generate, validate, and bank vector constructs for expression of candidate biotherapeutic molecules in mammalian cell systems • Perform molecular characterization of cell lines and constructs using techniques such as dd PCR, Sanger sequencing, and restriction mapping • Support NGS library preparation for genomic and transcriptomic analysis of CHO cell lines • Optimize and troubleshoot molecular biology protocols to improve efficiency and reproducibility • Prepare technical reports and presentations to communicate progress and data Basic Qualifications • PhD (0-3 years) in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or related discipline • Extensive hands-on experience with molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction cloning, and PCR-based methods • Demonstrated expertise in DNA construct design, vector engineering, and plasmid preparation • Experience with genetic characterization methods such as dd PCR, qPCR, gel electrophoresis, and DNA sequencing analysis • Proficiency in designing and optimizing molecular biology workflows for automation on liquid handling platforms (Hamilton, Tecan, or similar) • Strong technical background in molecular biology with excellent attention to detail and troubleshooting skills • Self-motivated with excellent organization, time-management, and communication skills • Maintain detailed electronic laboratory notebooks and documentation of all experimental procedures • Demonstrated ability to work as member of a team and adhere to timelines Preferred Qualifications • Mammalian cell culture experience in a pharmaceutical or biotechnology setting, particularly with CHO cells • Experience with high-throughput screening and clone selection strategies • Familiarity with bioinformatic tools for DNA sequence analysis, primer design, and in silico cloning (Snapgene, Geneious, Benchling, Primer3 or similar) • Knowledge of CHO cell line development processes and recombinant protein expression • Experience using Oxford Nanopore Technologies in NGS workflows • Basic programming skills in R or Python for data analysis and visualization • Experience with Bash/command line scripting for bioinformatics workflows and data processing • Experience with automated colony picking and clone tracking systems • Flexibility to adjust to a fast-paced, goal-oriented environment and willingness to expand and broaden skillset As a healthcare company and a vaccine manufacturer, we have an important responsibility to protect individual and public health. All US-based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities. According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE. #GD-SA #LI-SA PDN Diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

Machine Learning Scientist - LLM Systems for Scientific Discovery About the Team Join the internal AI initiative of a prominent venture studio that has launched 100+ life sciences companies (including Moderna). You'll be part of a ~20-person technical team in Cambridge building advanced LLM and ML systems that accelerate scientific breakthroughs and help launch new AI-first ventures. What Will I Be Doing: Research & prototype novel LLM workflows (agents, reasoning systems, tool-use frameworks) tailored to scientific applications Define success metrics and design custom benchmarks to evaluate AI systems across diverse scientific domains Collaborate with ML engineers to scale promising prototypes into production systems Stay at the frontier by synthesizing state-of-the-art research and validating findings through rigorous experimentation Build feedback loops that incorporate user testing into system development What We're Looking For: PhD in machine learning, computer science, statistics, physics, mathematics, or related quantitative field Research excellence in LLMs or adjacent areas (reasoning/agents, sequence modeling, representation learning, optimization) demonstrated through publications at top venues or impactful work Hands-on ML experience with PyTorch or JAX, including reproducible experiment workflows Strong Python skills and fluency with standard ML tools Ability to work independently while collaborating effectively in a small team Experience building LLM systems: agentic frameworks, RAG, multi-agent simulations, RLHF/DPO, or evaluation methodologies Domain knowledge in chemistry, biology, physics, materials science, or related fields What's in it for me: Competitive Compensation: $140k-$240k dependent on experience Work on originating and fostering breakthrough ventures transforming human health and sustainability Relocation assistance available (typically $10k sign-on bonus) Apply now for immediate consideration!

Data and Evaluation Applied AI Scientist (Battery Informatics and Scientific AI Systems) $180k - $310k A fast growing energy technology company is expanding its AI research division and is looking for a Data and Evaluation Applied AI Scientist. The team builds advanced AI systems to accelerate discovery in energy storage and next generation battery materials. This role focuses on data correctness, scientific reasoning quality, and the integrity of battery domain knowledge used to train LLMs and multi agent scientific frameworks. The company combines material science and applied AI to develop high energy Li Metal and Li ion battery technologies. Their platform uses AI enhanced discovery to design electrolytes, model electrochemical behavior, and develop new materials with real world applications across transportation, robotics, aerospace, and long duration energy storage. What You Will Do • Translate complex battery materials knowledge into structured, high quality, AI trainable datasets • Lead rigorous data validation, cleaning, and annotation processes to ensure scientific correctness • Create benchmark datasets and design multimodal evaluation suites for model testing • Partner with AI architecture teams to assess and refine model reasoning across chemistry, materials, and electrochemical concepts • Apply techniques that improve correctness and alignment, including methods inspired by human feedback systems • Ensure that AI models demonstrate accurate understanding of molecular behavior, materials interactions, and battery domain logic • Drive the application of battery informatics principles across data pipelines and model development What You Bring • PhD in Chemical Engineering with a focus on lithium battery systems or in Materials Science or a closely related computational field • Deep domain expertise in battery materials and electrochemical systems • Strong experience converting scientific data into AI trainable structures • Practical experience with data validation, annotation, and benchmark dataset creation • Exposure to LLM pipelines, AI evaluation, or multi agent scientific workflows • Background in an applied science or AI for materials role Preferred Experience • Hands on experience with RLHF or other model tuning and alignment techniques • Work history in battery labs, materials informatics teams, or AI4Science groups • Experience designing domain specific evaluation frameworks for complex AI systems • Experience as a computational battery AI specialist

Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Process R&D Scientist plays a key role in developing and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs). This position conducts small- to large-scale chemical reactions and generates high-quality data that supports project decision-making and innovation. Working under the guidance of technical leads, the role contributes to delivering projects on time, on spec, and within budget. It's an excellent opportunity to deepen expertise while supporting impactful pharmaceutical development. Core Responsibilities: Delivers experimental output with high scientific integrity, meeting targets, timelines, and quality expectations with guidance. Exhibits strong safety awareness, conducts laboratory and operational activities safely, and maintains accountability for safe behavior in the work environment. Maintains technical equipment and related services to ensure proper functionality. Acts on feedback and demonstrates a continuous commitment to learning and professional development. Leads technical and operational areas and supports troubleshooting for complex scientific issues with minimal guidance. Shares knowledge, skills, and experience effectively with internal and external stakeholders; may lead focused projects as a key contact. Keeps accurate, legible, and complete records of all experiments, observations, and equipment use. Writes high-quality reports and delivers presentations to customers and management with some guidance, aligned with project milestones. Contributes to maintaining strong customer relationships and identifies new commercial opportunities. Actively supports the technical development of the department and the broader organization. Ensures all documentation meets Veranova standards; supports audit readiness and participates in regulatory and customer audits as needed; reports near misses and safety incidents per company procedures; and ensures all work complies with applicable state and federal regulations, including GMP, DEA, and FDA requirements. Adheres to all EHS policies and procedures; demonstrates strong technical and procedural proficiency in applying EHS standards; supports EHS audit readiness and participates in audits; reports and cooperates fully in investigations of near misses and incidents; and upholds Veranova's EHS commitments by integrating ISO 14001, OHSAS 18001, and Sustainability 2025 principles into daily work. Performs additional duties within the employee's skills and abilities as reasonably assigned. Qualifications: Required PhD degree (or equivalent experience) in a chemistry related discipline. Proficiency with relevant lab and analytical techniques. Previous industry experience in relevant areas. Proficiency with relevant analytical techniques within an industry environment. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and other relevant technical software platforms. Skilled in written and spoken communication and proven ability to effectively interact with management. Demonstrates good judgment, quick decision-making skills, and the ability to work independently and in a team environment. Special Factors Must be able to stand, walk, and manually operate objects, tools, or controls; reach with hands or arms; and climb, balance, stoop, kneel, or crouch when necessary for the job activity. Must be able to lift and/or move up to 50 pounds. Specific vision abilities include near, distance, peripheral, color perception, and the ability to adjust focus. May regularly work with moving mechanical parts and may work with toxic or caustic chemicals. May work in humid areas with low or high temperatures. May be required to work with a respirator or operate with full-body Tyvek suits and supplied air or PAPR. Salary Range : $105,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .

Job Tittle: Senior Food Scientist Work Authorization : US Citizen and Green Card This role will lead the development and improvement of nutritional beverages and powders from concept to commercialization, driving innovation that ensures exceptional quality, stability, and clinical impact. Responsibilities Develop and optimize nutritional beverage and powder formulations that meet nutritional, sensory, and stability goals. Partner with Medical Nutrition, Marketing, and Sales to align product design with business and patient needs. Research and evaluate new ingredients and explore new medical nutrition opportunities. Support leadership with technical and scientific expertise for product and clinical development. Build vendor relationships to source ingredients that meet product requirements. Present company research at scientific meetings and conferences. Ensure strong intellectual property protection for new products and processes. Follow all GMP, food safety, and workplace safety policies. MUST HAVES: Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus). 5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries. Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company. Strong background in food science, ingredient interactions, and process impact on nutrient stability. Knowledge of food safety standards and aseptic processing AI-generated to support your search process-please use them as guidance and apply your own best judgment when making decisions Benefits Competitive salary and performance-based bonus (12.5%) program Comprehensive health, dental, and vision insurance Paid time off and holidays 401(k) with company match Opportunities for professional growth and advancement Employee discount programs

Title:- Scientist I Duration: Contract until Jan 2027 (Two-year assignment with possibility to convert depends on performance and project needs) COVID VAX IS REQUIRED PRIOR TO STARTING Description: The Cell Line Development Department at *** is seeking a highly motivated Molecular Biology Scientist to join a high-performing, collaborative team focused on optimizing CHO cell line development platforms through advanced molecular biology techniques and automation. Responsibilities will focus on improving process workflows, expression system components, and CLD methods used to generate recombinant CHO cell lines for production of protein biologics. This will include the design and generation of next generation vector topologies utilizing modern cloning strategies such as Gibson assembly and Golden Gate cloning. The ideal candidate will possess expertise in high-throughput molecular biology workflows and automated vector construction pipelines. Work will directly support development projects in ***'s pipeline and will include frequent cross-functional interactions with colleagues in ***'s global CMC sites (US, France). Key Responsibilities • Design and construct expression vectors using advanced molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction enzyme-based cloning, and site-directed mutagenesis • Develop, optimize, and implement automated workflows for high-throughput vector construction and DNA assembly on liquid handling platforms • Generate, validate, and bank vector constructs for expression of candidate biotherapeutic molecules in mammalian cell systems • Perform molecular characterization of cell lines and constructs using techniques such as dd PCR, Sanger sequencing, and restriction mapping • Support NGS library preparation for genomic and transcriptomic analysis of CHO cell lines • Optimize and troubleshoot molecular biology protocols to improve efficiency and reproducibility • Prepare technical reports and presentations to communicate progress and data Basic Qualifications • PhD (0-3 years) in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or related discipline • Extensive hands-on experience with molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction cloning, and PCR-based methods • Demonstrated expertise in DNA construct design, vector engineering, and plasmid preparation • Experience with genetic characterization methods such as dd PCR, qPCR, gel electrophoresis, and DNA sequencing analysis • Proficiency in designing and optimizing molecular biology workflows for automation on liquid handling platforms (Hamilton, Tecan, or similar) • Strong technical background in molecular biology with excellent attention to detail and troubleshooting skills • Self-motivated with excellent organization, time-management, and communication skills • Maintain detailed electronic laboratory notebooks and documentation of all experimental procedures • Demonstrated ability to work as member of a team and adhere to timelines Preferred Qualifications • Mammalian cell culture experience in a pharmaceutical or biotechnology setting, particularly with CHO cells • Experience with high-throughput screening and clone selection strategies • Familiarity with bioinformatic tools for DNA sequence analysis, primer design, and in silico cloning (Snapgene, Geneious, Benchling, Primer3 or similar) • Knowledge of CHO cell line development processes and recombinant protein expression • Experience using Oxford Nanopore Technologies in NGS workflows • Basic programming skills in R or Python for data analysis and visualization • Experience with Bash/command line scripting for bioinformatics workflows and data processing • Experience with automated colony picking and clone tracking systems • Flexibility to adjust to a fast-paced, goal-oriented environment and willingness to expand and broaden skillset As a healthcare company and a vaccine manufacturer, *** has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities. According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pharmaceutical vaccine, or (b) the single dose of the Pharmaceutical vaccine. Fully vaccinated, for new *** employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE. MINAKSHI SANGWAN Recruiting Lead - US Recruitment O ************ E *************************** W **********************

. You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate. Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; leads or actively participates in portfolio- and enterprise level workgroups aimed at optimizing PFE clinical development procedures; may be a subject matter expert or business process owner for a relevant SOP or procedure. MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval Excellent knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations Extensive understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance Experience working on large data sets Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery Experience leveraging a variety of communication tools and techniques to communicate results Experience solving problems collaboratively and handling conflict constructively Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations Experience working proactively and independently, organizing tasks, time and priorities of self and others Experience building partnerships across the company to achieve the needs of the program PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. both as a leader and a key contributor Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss. The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group. The position is responsible for all aspects of project management including project proposals, execution, and reporting. The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce. #FMG #LI-TA1

About Us: SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology. Harness internal expertise and collaborate with external research labs to advance scientific ML. Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery. This position can be remote. Essential Duties and Responsibilities: Research & Development Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery. Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference. Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions. Model Optimization & Implementation Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency. Implement innovative solutions to enhance model performance and scalability. Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology. Collaboration & Communication Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences. Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently. The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members. Education and/or Experience: MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience. Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models. Proficiency in programming languages relevant to machine learning, with a strong preference for Python. Experience with deep learning frameworks such as PyTorch or TensorFlow. Proficiency in utilizing causal graphs for AI research and application. A solid track record of innovative research, preferably with published work in relevant areas. Excellent problem-solving abilities and a passion for tackling complex technical challenges. Preferred Qualifications: Experience with AI applications in material science or battery technology. Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.

Job DescriptionSalary: The Scientist will contribute to Extractables & Leachables studies performed in the E&L laboratory at Boston Analytical to support client submissions. The ideal candidate will have experience operating LC-MS and GC-MS systems for analysis of volatile, semi-volatile, and nonvolatile organic extractables and leachables samples. PRIMARY DUTIES AND RESPONSIBILITIES Prepares extractions for analysis. Analysis of sample extract solutions by GC-MS and LC-MS to adequately resolve and identify all compounds. Coordinate findings with the team to generate conclusions. Author detailed cGMP report sections for work performed outlining study findings. Develop analysis methods for drug product leachables testing. Performs system maintenance and calibrations to ensure equipment is operating with specified requirements. Ensures all work performed strictly adheres to Company, client and Pharmacopial requirements. Proper handling of hazardous waste in compliance with the Company and DES hazardous waste rules. REQUIREMENTS & QUALIFICATIONS Qualification includes a Ph.D. in Analytical Chemistry with 2+ years experience or a Masters degree and 4+ years experience or a Bachelors with 6+ years of experience performing and interpreting MS analysis. Knowledge of current Extractable & Leachables guidance (USP, ISO 10993) and best practices preferred. Experience working in a cGMP environment required. MINIMUM SKILLS REQUIREMENTS Must have the ability and skill to perform the detailed job requirements noted above competently, safely and proficiently. A self-starter, motivated person who possesses good interpersonal skills capable of effectively interacting with all departments and client personnel. Must have excellent organizational, verbal communication and technical writing skills. Must be a team player with integrity and concern for the quality of Company products, services and staff members. Demonstrated LC-MS and/or GC-MS operation and data interpretation capability. Ability to develop and optimize HPLC, UPLC, and GC methods. Documented success managing complex projects to completion within customer expectations for deadline, cost, and overall deliverable

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. The LIGM RNA Group is seeking an experienced analytical scientist with extensive hands-on experience in analytical techniques for characterizing and analyzing small molecules, biologics, and/or oligonucleotides. The ideal candidate will have a proven track record in analytical method development and troubleshooting, as well as experience with liquid chromatography, (high resolution) mass spectrometry, and other advanced analytical techniques. They must possess strong technical problem-solving skills, be computer savvy with the ability to navigate multiple instrument control programs and data analysis environments, and be able to work independently to achieve efficient, quality results in a fast-paced environment. Responsibilities: Work closely with the chemistry team to source, explore, and implement the latest separation science and analytical technologies for the purification and characterization of oligonucleotides and their conjugates, including carbohydrates, lipids, peptides, and proteins. Conduct LC and LC-MS based method development for sensitive characterization of biologics including intact mass, reduced mass, peptide mapping, and glycan mapping to provide better understanding of attributes. Conduct semi-preparative and preparative method development activities to advance downstream processing for challenging modified oligonucleotides, utilizing RP purification, ion-exchange chromatography, spin filtration, TFF, FPLC, size exclusion chromatography, and MS-direct auto-scale preparative LC-MS techniques. Work with contractors and third-party vendors to troubleshoot and maintain lab instruments, including but not limited to UPLC, LC-MS, osmometer, and NanoDrop, ensuring they remain in peak operational condition. Learn new technologies quickly and apply effective scientific concepts and methods across multiple areas. Process and present data leveraging Microsoft Office apps, GraphPad and Spotfire for data organization and data visualization. Document experiments, data, technical reports, and findings electronically in an accessible manner with good documentation practices. Present findings, progress, and data proactively and regularly in group and department meetings. Possess a collaborative and willing-to-share mindset with excellent verbal and written communication skills, presentation skills, and attention to detail. Ability to follow Global Health, Safety & Environment Center (HSE) guidelines while performing tasks. Basic Qualifications: Bachelor's or Master's degree in Analytical Chemistry, Biochemistry, Chemistry, Food Science, or a related scientific field, with over 2 years of relevant post-graduate experience in industry. Additional Skills/Preferences: Strong analytical thinking skills with a demonstrated ability to articulate issues and extract and synthesize complex information into key focus areas. Extensive experience in operating and troubleshooting a range of mass spectrometers including Q-ToF, QQQ and Orbitrap Proficient with Thermo XCalibur, Agilent ChemStation and MassHunter software. Understanding tandem mass spectrometry and interpretation of MS/MS based characterization of including but not limited to peptide, peptide-oligonucleotide conjugates, and lipid conjugates. Extensive hands-on experience in downstream workflows for small molecules, biologics, and oligonucleotides. Experience with antibody-drug-conjugates (ADCs) or antibody-oligonucleotide-conjugates (AOCs) is a plus. Proven expertise in liquid chromatography including ion-pair reverse phase liquid chromatography as well as ion chromatography. Prior experience in native mass spectrometry and understanding of electrospray ionization as well as molecular behavior in the gas phase. Prior experience in proteomics, bioanalysis, and/or CMC is a significant advantage. Highly self-motivated and self-driven attitude with ability to own and drive projects into success. Strong organizational and communication skills and effective people skills. Capable of continuous learning, open-minded, highly organized, and detail oriented. Ability to balance multiple activities, prioritize and handle ambiguity. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

Title: Toxicologist The Toxicologist will play a critical role in the assessment of the safety profile of small molecule drug candidates throughout the drug development process. This position requires a deep understanding of toxicological principles, regulatory requirements, and the ability to interpret complex data to inform decision-making. Responsibilities Conduct comprehensive toxicological evaluations of small molecules Analyze data from non-clinical studies to identify potential safety concerns and recommend strategies for risk mitigation. Prepare toxicology sections for regulatory submissions (INDs, NDAs) in accordance with FDA, EMA, and ICH guidelines. This will include liaising with the regulatory agencies related to toxicological data. Participate in project teams to provide expert advice on safety-related issues throughout the product lifecycle. Conduct risk assessments based on toxicological data to support decision-making processes regarding compound progression Profile Ph.D. or equivalent degree in Toxicology, Pharmacology, or a related field Mulitple years experience in the pharmaceutical or biotechnology industry. Small molecules experience Strong knowledge of GLP regulations, ICH guidelines, and FDA/EMA submission requirements. Experience working directly with regulatory agencies is an advantage. Benefits: Competitive salary with performance-based bonuses and comprehensive benefits package Home office option Excellent company culture

We are seeking a highly motivated and innovative Scientist to support the discovery and development of gene therapies for rare genetic diseases. The candidate is expected to have proven practical technical capability and experience in, cell culture and cell based assays, protein purification and analytical assays. She/he should be scientifically motivated and capable of critically analyzing and interpreting data and reporting experimental results. Strong presentation and communication skills and the ability to work in a fast-paced and team-oriented environment will be vital. The position will support the development of a pipeline of gene therapy - associated product concepts while working in a cross- functional and collaborative environment Skills: • Experience with mammalian cell culturing techniques and cell based assays. • Experience with PCR, qPCR, Southern / Western blotting, Experience with FPLC / HPLC systems. • Ability to work in a team orientated, collaborative environment Strong communication and presentation skills • Prior experience with production and purification of AAV vectors is a plus Keywords: Education: BS/MS with a minimum of 8 years of related experience Qualifications BS/MS with a minimum of 8 years of related experience

The Center for Cancer Genomics (CCG) at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities The Bioinformatician II will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects (sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing, etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. Qualifications MINIMUM JOB QUALIFICATIONS: Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. * Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). * Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. * Excellent communication skills and ability to work collaboratively in multi-disciplinary team. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

About the Opportunity The Bioinformatician will report to Ayan Paul, Research Scientist at EAI, and collaborate with Scientists and Clinicians from Peter Castaldi's group at the Harvard Medical School, John Platig's Network Biology group at the University of Virginia, and Jennifer Dy's group at ECE, Northeastern University. Responsibilities will include building an ETL pipeline for ENCODE genomics data, writing Python code for data analysis, and a downstream R pipeline for post-processing data using standard Bioinformatics libraries from Bioconductor. There will be opportunities to participate in building machine learning models, co-author publications, and contribute to grant proposals. Tentative start date: January 2024 for the Spring 2024 semester with possibilities of renewal. This work will contribute towards the understanding of genetic origins of complex diseases like Chronic Obstructive Pulmonary Disease and cutting-edge machine learning-based methodologies for regulation of mRNA splicing. RESPONSIBILITIES INCLUDE: Building ETL pipelines for genomics/transcriptomics data from public databases and processing them with publicly available codes in python and R. Documenting the entire process and all the codes generated and maintaining structured and regular commits in a GitHub repository. Helped implement machine learning models and automate the processing of input data. Write reports/prepare slide decks describing work performed. Contribute to scientific manuscripts and grant proposals where appropriate. MINIMUM QUALIFICATIONS: A Master's degree (or equivalent) A minimum of 3-4 years of experience working with data pipelines and data analysis. Proficiency in Python and R. Experience working in Unix OS and remote computing clusters. Have demonstrable expertise in bioinformatics, especially genomics, transcriptomics, proteomics and/or metabolomics, and have a good grasp of statistics. Experience working with genomics databases like ENCODE and familiarity with RNA-seq, eCLIP, and other data is highly desirable but not required. An ability to write clean and well-documented code and work with GitHub repositories. Position Type Temporary Additional Information Northeastern University considers factors such as candidate work experience, education and skills when extending an offer. Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation. Visit ************************************* for more information. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law. Pay Rate: $45/hour

Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Scientist role within the Chemical Development group will focus on the synthesis, process development, and analytical strategy for protected phosphoramidite precursors used in therapeutic oligonucleotide API manufacturing. This position is key to building Veranova's commercial capability in producing high-quality oligonucleotide building blocks. The ideal candidate will have strong expertise in phosphoramidite chemistry, including impurity profiling and customer-specific requirements. This role will also collaborate closely with the Analytical Team to establish robust characterization and control strategies that ensure exceptional product quality. Core Responsibilities: Develop and optimize synthetic routes for protected Phosphoramidite subunits used in therapeutic oligonucleotide API synthesis. Identify and mitigate side reactions commonly associated with Phosphoramidite chemistry. Define and implement specifications aligned with customer expectations for commercial-grade oligonucleotide precursors. Provide expert guidance to the Analytical Team on the selection and application of appropriate analytical methods for product and impurity characterization, based on prior experience and industry standards. Collaborate with cross-functional teams including Analytical Development, Quality, and Manufacturing to ensure successful scale-up and tech transfer. Prepare technical documentation including batch records, specifications, and development reports in accordance with SOPs and cGMP guidelines. Present scientific findings and project updates to internal stakeholders and external customers. Support the establishment of quality and regulatory standards for commercial production of oligonucleotide precursors. Contribute to project planning, budgeting, and timeline management for precursor development programs. Other duties as assigned . Qualifications: Required BS in Organic Chemistry or equivalent with 3-5 years related experience in a pharmaceutical industry, or MS in Organic Chemistry or equivalent with 0-2 years related experience in the pharmaceutical industry. Ability to read, analyze, and interpret English-language chemical periodicals, scientific journals, and regulatory documents. Experience with organic synthesis and process development Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS. Experience in establishing integrated plans with defined resources and tasks. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and statistical software. Demonstrate ability to exercise good judgment and make decisions quickly. Good written and verbal communication skills. Ability to work independently and in a team environment. Salary Range : $110,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research. The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research. This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering. Responsibilities: Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions. Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements. Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies. Publish and present research in peer-reviewed journals and at scientific or industry conferences. Contribute to strategic planning and innovation in wind engineering research initiatives. PhD degree. Mechanical, Civil, Aerospace Engineering or related fields. Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent). Proficient in programming languages such as C++, Python, R, MATLAB. Skilled in high-performance computing (HPC) and parallel computing environments. Experience with wind tunnel testing or field measurements is highly desirable. Familiarity with relevant building codes and standards is a plus. Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.

The **Center for Cancer Genomics** **(CCG)** at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The **Bioinformatician II** will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects ( _sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing,_ etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. **MINIMUM JOB QUALIFICATIONS:** Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. + Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). + Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. + Excellent communication skills and ability to work collaboratively in multi-disciplinary team. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**