Senior principal scientist jobs in Carnot-Moon, PA - 49 jobs

We are seeking an Applied Machine Learning Research Scientist to join our Accessibility efforts on the Human-Centered Machine Intelligence (HCMI) team within AIML at Apple. Research Scientists in HCMI tackle significant technical and human-centered research challenges, collaborate with partner teams across Apple to ship products, and shape the field of human-centered AIML via external publication and engagement. Join us to design, study, and build intelligent interactive technologies that enable people of all abilities to use Apple technology. The Human Centered Machine Intelligence (HCMI) group designs, studies, and builds interactive technologies that enable people to benefit from machine learning. We are a close-knit team of research scientists and engineers in a unique position to do research and work closely with product teams throughout Apple. Our work has resulted in numerous award-winning research publications and groundbreaking technologies impacting millions of people. The Accessibility team within HCMI specifically focuses on core ML technologies that address grand challenges in accessibility, including equitable speech access to people with disabilities, visual understanding for people who are blind or low vision, communication access for people who use sign language, and more. Experience designing machine learning models for sign language. Experience conducting research in Accessibility (e.g., sign language, atypical speech, visual accessibility, or other topics). Experience doing data collection or data curation (e.g., developing data or annotation protocols). Experience with human-centered evaluation methods (e.g., developing user study protocols or running studies). Experience developing and shipping products that use machine learning. Strong writing and presentation skills. PhD in Machine Learning, Human Computer Interaction, Computer Science, or related field. Experienced researcher in areas of machine learning, including computer vision or multi-modal modeling. Publication and research record commensurate with seniority. Proven history of turning research contributions into tools, guidelines, or products either commercially or as open source, or strong potential to do so.

Arconic is currently in search of Staff Scientist, Optimization & Data Analytics to join our Arconic Technology Team based in New Kensington, PA At Arconic, we take pride in our work and our innovative products and technologies that advance sustainable solutions for a better world. We strive to create a safe, inclusive, and collaborative workplace with competitive benefits, development opportunities and a culture that values and rewards employees on all levels of the organization. Job Summary: The Staff Scientist, Optimization and Data Analytics is responsible for developing and supporting optimization, scheduling, and analytics applications across Arconic's processes including casting, rolling, extrusion, etc. This role is part of our Research & Development team and will provide technical expertise to support operations and lead multi-disciplinary projects focused on optimization of aluminum forming/fabrication processes.

. . . . . NEW OPPORTUNITY Associate Director | Principal Scientist Pharmacology Immuno-Oncology Research This is your opportunity to join a start-up Immuno-Oncology Company and to be a significant contributor as they GROW! Do your skills include the following: Managing, developing, mentoring junior scientists? Overseeing CRO | external resources activity? Advancing assets from candidate selection to preclinical development to IND? PDX models, Humanized models, Xenograft models, etc.? Biomarker discovery | Biomarker strategy? To learn more about this exciting opportunity . . . . Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************

Carnegie Mellon University is a private, global research university that challenges the curious and hardworking to deliver work that matters. Our extraordinary institution has distinctive areas of excellence and a culture marked by ambition and a deep, practical engagement with challenges facing society. We continue to produce dedicated alumni and draw faculty and staff eager to be a part of the university's creative, dedicated and close-knit community. We place emphasis on practical problem solving, interdisciplinary learning, a transformative spirit, and collaboration. The Human-Computer Interaction Institute (HCII) is a living laboratory where we investigate the relationship between computer technology, human activity, and society. Founded in 1993, the HCII is a place where we work to understand and create technology that harmonizes with and improves human capabilities, goals, and social environments through interdisciplinary research and education in design, computer science, and behavioral and social sciences. We are looking for a Principal Research Scientist with expertise in computer science and natural language processing to help lead a project on crafting, implementing, testing, and commercializing a generative AI-based training environment to help non-clinical trainees learn to provide effective social support Core Responsibilities Include: Translating research goals into concrete research plans Applying AI and NLP concepts to technologies aimed at improving mental health Developing and testing generalizable principles of a social skills, simulation-based training environment Help developing high-fidelity prototypes of the training environment, which can be used to empirically test the training environment and be built upon as the basis of robust software for commercial deployment Supervising and mentoring junior PhD students and post-doctoral fellows working on the project Perform other duties as assigned Flexibility, excellence, and passion are vital qualities within the School of Computer Science Research Department. Collaboration and cultural sensitivity are valued competencies at CMU. Therefore, we are in search of a team member who is able to effectively interact with a varied population of internal and external partners at a high level of integrity. We are looking for someone who shares our values and who will support the mission of the university through their work. Qualifications: PhD in computer science and natural language processing Strong skills in computer science, natural language processing, and software engineering At least 5-years of experience conducting research in academia or industry Experience supervising PhD students and/or research staff Familiarity with theory and empirical research in interpersonal communication A strong track record of high-quality research publications in computational social science and natural language processing A combination of education and proven experience from which comparable knowledge is demonstrated may be considered. Requirements Successful background investigation Joining the CMU team opens the door to an array of exceptional benefits. Benefits eligible employees enjoy a wide array of benefits including comprehensive medical, prescription, dental, and vision insurance as well as a generous retirement savings program with employer contributions. Unlock your potential with tuition benefits, take well-deserved breaks with ample paid time off and observed holidays, and rest easy with life and accidental death and disability insurance. Additional perks include a free Pittsburgh Regional Transit bus pass, access to our Family Concierge Team to help navigate childcare needs, fitness center access, and much more! For a comprehensive overview of the benefits available, explore our Benefits page. At Carnegie Mellon, we value the whole package when extending offers of employment. Beyond credentials, we evaluate the role and responsibilities, your valuable work experience, and the knowledge gained through education and training. We appreciate your unique skills and the perspective you bring. Your journey with us is about more than just a job; it's about finding the perfect fit for your professional growth and personal aspirations. Are you interested in an exciting opportunity with an exceptional organization?! Apply today! Location Pittsburgh, PA Job Function Engineering, Research and Project Scientists Position Type Staff - Fixed Term (Fixed Term) Full Time/Part time Full time Pay Basis Salary More Information: Please visit “Why Carnegie Mellon” to learn more about becoming part of an institution inspiring innovations that change the world. Click here to view a listing of employee benefits Carnegie Mellon University is an Equal Opportunity Employer/Disability/Veteran. Statement of Assurance

Analyzes existing business system and designs business models and software applications. Develops models and applications based on advanced analytical methods and facilitates communications between Operations Research and end-users. These models and applications will enable informed, data-driven decisions and insights for efficiently running, planning, and transforming the business. Implements advanced analytical techniques such as mathematical modeling, optimization, statistics, machine learning, artificial intelligence, and simulation to drive industry leading concepts to solve complex business problems. Programs and designs the business operational models and software applications. Constructs new approaches and methodologies to enhance the business models. Manages, manipulates, and visualizes data for new and enhanced business operational models. Responsible for performing unit and system testing, including monitoring, and validating test results. Writes technical documentation in accordance with business framework. Develops ad hoc reports and big data analysis according to management requests. Collaborates with business analysts, field personnel, and other departments for problem resolutions. Perform other duties as assigned. Requirements Master's degree or equivalent in computer science, applied mathematics, Industrial Engineering, or related field required plus experience in Advanced application (can be through education / coursework) of two or more of the following: Java, SAS, SQL, and/or Python to analyze or design business models and software applications. Advanced application (can be through education / coursework) of two or more commercial optimization, simulation, ML or supply chain modeling engines and languages such as: CPLEX, Gurobi, Xpress, ESRI, Simio, AnyLogic, Tensorflow, Scikit Learn or Supply Chain Guru to analyze business problems. The employer will alternatively accept a Bachelor's degree in computer science, applied mathematics, Industrial Engineering, or related field required plus 2 years of experience in the job offered or 2 years of related experience in Advanced application (can be through education / coursework) of two or more of the following: Java, SAS, SQL, and/or Python to analyze or design business models and software applications. Advanced application (can be through education / coursework) of two or more commercial optimization, simulation, ML or supply chain modeling engines and languages such as: CPLEX, Gurobi, Xpress, ESRI, Simio, AnyLogic, Tensorflow, Scikit Learn or Supply Chain Guru to analyze business problems, in lieu of a Master's degree plus experience. The position requires experience with: Performance Data Analytics; Consolidation of Engineering info for Management; Expenditure proposals and cost justification analysis; Project Management fundamentals; Controlled self-monitoring; Supply Chain/Transportation operations. Exceptional analytical and problem-solving skills. Working knowledge of Operations Research (OR) and Analytics models. Working knowledge of cloud computing in environments such as Azure, Google Cloud Platform or Amazon Web Services. Working knowledge of data visualization tools such as Tableau, Spotfire, Power BI or d3.js. Experience explaining complex and/or confidential information via both verbal and written means. Presentation skills necessary to facilitate training and/or deliver information sessions to groups and /or individuals. Time management and organizational skills necessary to appropriately prioritize workload, plan for resources to meet deadlines and goals, and respond to day-to-day functional needs. Experience anticipating and identifying problems and using judgment and fact-based analysis to develop effective and efficient solutions. Bachelor's degree with two years related experience satisfies the education requirement. Position allows for telecommuting from home within commuting distance of Moon Township, PA.

The Bosch Research and Technology Center North America with offices in Sunnyvale, California, Pittsburgh, Pennsylvania and Cambridge, Massachusetts is a part of the global Bosch Group /home/bou1pi/workspace/active-learning-toolchain/actlearn/training/config/model/frontend/gabor.yaml (*************** a company with over 90 billion euro revenue, 400,000 employees worldwide, a very diverse product portfolio, and a history spanning over 125 years. The Research and Technology Center North America provides technologies and system solutions for various Bosch business fields, primarily in the field of artificial intelligence (for example, human-assisted AI, natural language processing, robotics, 3D perception, and AI platform), energy technologies, internet technologies, circuit design, semiconductors and wireless, as well as advanced MEMS design. The Bosch Research and Technology Center in Pittsburgh, PA is focused on the research and development of cutting-edge AI and sensing technologies that will shape the future of the company's products. This position is part of an ambitious effort to design and develop intelligent multi-modal sensing at the intersection of deep learning and signal processing, with diverse application domains ranging from physical security to intelligent and connected vehicles. Job Description Originating from Bosch AI research in Pittsburgh, we are responsible for pushing the boundaries of signal sensing and multimodal models through key innovations to solve complex industry problems and shape the future of Bosch products and services for both internal and external users. We work with internal partners of different Bosch business units to transfer our solutions into future products. We also actively collaborate with leading groups in academia and industry to promote research ideas and publish research findings in internationally renowned conferences and journals. In this position, you are expected to: Develop and lead research projects focusing on multi-sensor data fusion, including acoustic, vibration, radar, lidar, image, Wi-Fi, time series, and ultrasound data, to improve sensing capabilities in autonomous driving vehicles, predictive maintenance in manufacturing processes, and next generation smart home devices, leading to enhanced safety, efficiency, and user experience. Design, build, train, evaluate multi-modal deep-learning models that leverage sensor signals, and work together with several business units within Bosch to transfer research artifacts into products and processes. Offer expert insights to the management team in relevant technology sectors, aiding in strategic planning, R&D trajectory, and investment decisions. Stay abreast of the latest technological innovations, document and disseminate research findings through high-caliber publications and/or patent submissions. Qualifications Basic Qualifications Ph.D. in Computer Science, Electrical Engineering, Information Technology or a related discipline In-depth experience in signal processing for sensor data and their integration with deep-learning methods. Proficiency in Python, PyTorch (including libraries such as torchaudio, torchvision, torchmetrics), familiarity with PyTorch Lightning. A strong publication record in relevant venues such as ICASSP, InterSpeech, WASPAA, SenSys, IPSN, ICCPS, ICML, ICLR, ICRA, CVPR, ICCV, ECCV, NeurIPS, or equivalent contributions to the field such as patents or significant open-source projects. Strong interpersonal, communication, and teamwork capabilities. Preferred Qualifications 3+ years of experience in industrial research. Proficiency with version control systems (Git), integrated development environment (VSCode or PyCharm) and experience with experiment tracking tools (MLFlow). Familiarity with high-performance computing (HPC) systems and job schedulers (Slurm, LSF). Hands-on experience in product development in the above-mentioned areas for consumer/enterprise markets. Experience leading projects with small teams, demonstrating the ability to mentor junior researchers and interns, manage project timelines, and deliver results within time constraints. Additional Information Equal Opportunity Employer, including disability / veterans. *Bosch adheres to Federal, State, and Local laws regarding drug-testing. Employment is contingent upon the successful completion of a drug screen and background check. Candidates who have been offered the position must pass both screenings before their start date. #LI-JM1

The CyLab Security and Privacy Institute (********************** at Carnegie Mellon University is searching for a special faculty systems scientist to teach and conduct research in the usable privacy and security and technology ethics areas. CyLab works to catalyze, support, promote, and strengthen collaborative security and privacy research and education across departments, disciplines, and geographic boundaries to achieve significant impact on research, education, public policy, and practice. CyLab is a university-wide umbrella organization that includes over three dozen core faculty and their students as well as over 100 affiliated faculty. New faculty members will be expected to both contribute to and benefit from the collaborative spirit that is a hallmark of Carnegie Mellon University and CyLab. Successful applicants will be appointed to CyLab, within the College of Engineering, but may be offered affiliate faculty or similar appointments in other academic departments. For any questions or concerns please contact us at *********************************** and a staff member will respond in a timely fashion. **Qualifications** **Application Instructions** Applications should be submitted through the CyLab Interfolio site by May 15, 2025. Applications may be shared with members of any of the participating departments Applicants should submit the following: 1. Cover letter 2. Detailed curriculum vitae 3. Teaching statement 4. Research statement 5. (3) Confidential Letters of Recomendation 6. Copies of 3 representative papers 7. A broader impact statement **Equal Employment Opportunity Statement** **Carnegie Mellon University** is an equal opportunity employer. It does not discriminate in admission, employment, or administration of its programs or activities on the basis of race, color, national origin, sex, disability, age, sexual orientation, gender identity, pregnancy or related condition, family status, marital status, parental status, religion, ancestry, veteran status, or genetic information. Furthermore, Carnegie Mellon University does not discriminate and is required not to discriminate in violation of federal, state, or local laws or executive orders.

Sr Scientist, R&D - Product Development Role This is a technical leadership role providing direction for and execution of projects across one or more of our US businesses. The candidate will be identifying, scoping and driving technical projects to meet business initiatives. This candidate should have a proven record of executing work plans and driving for results. This includes understanding business needs, designing and executing tests, analyzing data, drawing conclusions, documenting, communicating results, and commercializing products. Proven communication and teamwork skills are essential in this role, which operates in a cross-functional environment. The candidate must also have a strong technical background and be able to apply prior learning or scientific principles to new situations. This position requires an individual to manage multiple assignments/ tasks concurrently and demonstrate the ability to complete work with minimal guidance. Exhibiting a collaborative mindset and applying innovative solutions are a must. Key Components * Responsible for ideating, developing, and commercializing new products, renovating existing products, and delivering cost savings. * The candidate will be scoping and/or developing highly technical and complex project plans to meet the business' platform and innovation objectives over planning horizons ranging from months to quarters. * Assess potential food safety or quality risk associated with product development briefs, proposed manufacturing processes and/or equipment utilization. * Recommend mitigation strategies to ensure compliance with safety standards, quality expectations, and government regulations. * Evaluate the financial objectives of product development initiatives, such as COGS (VIC/VLC) targets, project budgets, expenditures, research and development appropriations, or return-on-investment and profit-loss projections. * Opportunities may exist to lead and mentor junior developers on projects. * Support graphics and label development and provide technical approval. * Evaluate quality of materials or products. Test quality of materials or finished products including shelf-life assessment. * Establish standards for products, processes, or procedures. * Develop specifications for new products or processes. * Develop new or improved ways of preserving, processing, packaging, storing, and delivering foods, using knowledge of chemistry, microbiology, and other sciences. * Stay current on new regulations and current events regarding food science by reviewing scientific literature. * Manage multiple assignments/ tasks concurrently and demonstrate the ability to complete work with minimal guidance. * Confer with process engineers, plant operators, flavor experts, and packaging and marketing specialists to resolve problems in product development. * Ability to scale up products from bench top to full line commercialization at the factory level * Interact cross functionally across the organization and influence others to drive projects to completion * Create project status presentations for delivery to customers, project personnel, or executive leadership. Qualifications * BS/MS in Food, Dairy, Meat, Animal Science, Packaging or Chemical Engineering * Minimum of 5 years in a Technical Function (which can include all graduate and/or internship work) * Culinary experience desired * Solid understanding of food chemistry, analytical testing, formulations and processing used in food manufacturing * Prior experience working with Sauces, condiments, and shelf stable products preferred * Understanding of ingredient functionality and interactions with process, and packaging * Excellent communication, influencing, project management and problem-solving skills * Independently manage and prioritize concurrent work assignments. * Strong understanding of Design of Experiments, statistical process control, data interpretation. * Willingness to travel 30-40% Our Total Rewards philosophy is to provide a meaningful and flexible spectrum of programs that equitably support our diverse workforce and their families and complement Kraft Heinz' strategy and values. New Hire Base Salary Range: $89,800.00 - $112,200.00 Bonus: This position is eligible for a performance-based bonus as provided by the plan terms and governing documents. The compensation offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors Benefits: Coverage for employees (and their eligible dependents) through affordable access to healthcare, protection, and saving for the future, we offer plans tailored to meet you and your family's needs. Coverage for benefits will be in accordance with the terms and conditions of the applicable plans and associated governing plan documents. Wellbeing: We offer events, resources, and learning opportunities that inspire a physical, social, emotional, and financial well-being lifestyle for our employees and their families. You'll be able to participate in a variety of benefits and wellbeing programs that may vary by role, country, region, union status, and other employment status factors, for example: * Physical - Medical, Prescription Drug, Dental, Vision, Screenings/Assessments * Social - Paid Time Off, Company Holidays, Leave of Absence, Flexible Work Arrangements, Recognition, Training * Emotional - Employee Assistance Program , Wellbeing Programs, Family Support Programs * Financial - 401k, Life, Accidental Death & Dismemberment, Disability Location(s) Heinz Innovation Center Kraft Heinz is an Equal Opportunity Employer - Underrepresented Ethnic Minority Groups/Women/Veterans/Individuals with Disabilities/Sexual Orientation/Gender Identity and other protected classes. In order to ensure reasonable accommodation for protected individuals, applicants that require accommodation in the job application process may contact *********************** for assistance.

Title: LCMS Research Scientist Type: 6-month contract to hire Hours: 8AM-5PM Start: January Join as a Research Scientist to will be responsible for developing, optimizing, and validating LC-MS assays to support research and development efforts. This role involves method development, sample preparation, data acquisition, data analysis, troubleshooting, instrument maintenance, and documentation in a regulated or research environment. This role will be involved in collaborative efforts and provide scientific leadership in LCMS-based analytical projects. Responsibilities + Involved in applying and maintaining complex LCMS (liquid chromatography and mass spectrometry) instrumentation. + Managing collaborative research projects, while developing and validating LC-MS methods (quantitative and/or qualitative) for small molecules, peptides, proteins, metabolites, or other analytes. + Design experiments for project and method development, operate and maintain mass spectrometers (e.g., triple quadrupole, Orbitrap, Q-TOF) and LC instrumentation, process and analyze mass spec data using relevant software + Interpret data scientifically and ensure quality control, write and review method standard operating procedures and protocols, and present data. + Maintain a safe laboratory environment, comply with safety and regulatory policies, and manage laboratory supplies and inventory. + Contribute to continuous improvement and innovation in bioanalytical techniques, instrumentation, and workflows with the opportunity to train junior staff / scientists in LCMS techniques, good laboratory practices, and data analysis. Requirements + MUST have PhD degree in chemistry, biochemistry, or related scientific discipline with relevant postdoctoral or industrial experience. + Must have expertise in instrument maintenance, sample preparation and method development across multiple platforms including metabolomics, lipidomic and proteomics + A strong work ethic, communication skills, ability to troubleshoot, be detail orientated and organized, and be able to manage multiple interdisciplinary projects and timelines with minimal supervision Physical Effort Moderate physical effort required. May be required to sit, stand or move for several hours at a time. May be required to move objects up to 50 pounds with or without assistance of equipment. System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M3 #LI-MD1 Ref: #558-Scientific System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

Conducts independent scientific research projects from inception to presentation. Prepares and crafts various documentations of research results into manuscripts, proposals, grant applications, and presentations. Trains undergraduates and research technicians. Manages laboratory policies and coordinates project development in collaboration with other specialists.

At Skild AI, we are building the world's first general purpose robotic intelligence that is robust and adapts to unseen scenarios without failing. We believe massive scale through data-driven machine learning is the key to unlocking these capabilities for the widespread deployment of robots within society. Our team consists of individuals with varying levels of experience and backgrounds, from new graduates to domain experts. Relevant industry experience is important, but ultimately less so than your demonstrated abilities and attitude. We are looking for passionate individuals who are eager to explore uncharted waters and contribute to our innovative projects. Position Overview We are looking for Research Scientists to lead the effort in developing the next generation of techniques to advance the capabilities of our robotic systems. We are looking for people with proven expertise in machine learning and/or robotics, who are passionate about pushing the boundaries of what is possible. You will collaborate with a team of talented researchers and engineers, and enhance our cohesive research strategy, driving ongoing innovation and technological advancements within the company. The ideal candidate will have a track record of discovering fundamental, scalable solutions, and a passion for seeing their research transform into impactful applications. Responsibilities Develop new algorithms and methods for training general-purpose robot foundation models. Conduct cutting edge research across multiple disciplines (Perception, Robotics, RL / IL, Machine Learning, etc.). Work with large scale systems and large-scale model training. Preferred Qualifications PhD degree in Computer Science, Robotics, Engineering or a related field, or equivalent practical experience. Multiple years of experience in conducting research. Proficiency in Python and at least one deep learning library such as PyTorch, TensorFlow, JAX, etc. Publications at top-tier ML, robotics, or CV conferences (e.g., NeurIPS, ICML, ICLR, CoRL, RSS, ICRA, CVPR, ECCV, ICCV). Deep technical knowledge, and research experience in deep learning, reinforcement learning, robotics, or computer vision. Deep understanding of state-of-the-art machine learning techniques and models. Experience working with robot systems. Experience working with large-scale model training and systems. Base Salary Range $100,000 - $300,000 USD

The Sr. Food Scientist will be technically sound, creative and will be responsible for formulation and processing support of new customer business across multiple plants within the Tandem Foods network. This role has a heavy emphasis on production support, and the Sr. Food Scientist must be comfortable and confident supporting a production environment. A successful candidate will lead by providing technical support both at the benchtop and plant level. This position will focus on owning new product pipeline projects and formulation initiatives with attention on building relationships with new customers and working collaboratively across all functions of the organization. Key Responsibilities Lead formulation development and processing support for new and existing customer projects across multiple manufacturing sites. Expected to be the technical expert on R&D subject matter to support production through the commercialization process and beyond to provide ongoing support to plant operations Troubleshoot challenges in formulation and process that are mindful of safety and costs while providing timely and effective solutions Collaborate with cross-functional teams including Sales, Operations, and Food Safety and Quality to align technical solutions with business objectives Work closely with customers to ensure product expectations are achieved and relationships are strengthened Plan, execute, and summarize plant trials for internal and external customers Preparation and execution of all related technical and business documentation Maintain accurate documentation of formulations, test results, and project progress Interact with ingredient suppliers to onboard new raw materials and trouble shoot formulation challenges Creative thinker with the ability to translate into stable product formulation Create new snack products utilizing Genesis as a formulation tool Present new formulation concepts to our sales team for external customer presentations Stay abreast of new ingredient developments as well as processing and equipment advances applying them to enhance project work Participate in sensory evaluation to drive decisions that are best for our customers Ability to taste and screen ingredients and finished products without dietary limitations Key Competencies Creative Thinking: Thinks outside the box, contributes ideas for new product concepts with the ability to bring them to life Customer Focus: Understands and monitors the needs of internal and external customers Adaptable / Flexible: Open to change in response to new information, different or unexpected circumstances Cross-Functional Collaboration: Ability to work in a dynamic team environment Self-Starter: Takes initiative in developing programs to conform with set standards, focusing on continual improvement Problem-Solving: Prevents and solves issues from a technical prospective, understand and mitigates problems, recognizes cause and effect relationships between functions Project and Time Management: Plans tasks and deliverables accurately, prioritizes tasks and adapts as needed and is responsive to requests and accountable for actions Qualifications Bachelor's degree in food science or another science-based field 5-8 Years' experience in a product development position preferably in a manufacturing environment Strong understanding of food formulation, ingredient functionality, and processing technologies Effective interpersonal and written communication skills with the ability to build relationships cross-functionally and externally Strong working knowledge of the food industry Excellent problem-solving, organizational and prioritization skills Experience with formulating protein bars, baked products and / or confections Proficient in MS Office suite including Excel and PowerPoint Working knowledge of Genesis Familiarity with regulatory requirements (FDA, etc.) Willingness to travel to manufacturing sites and customer locations as needed Work Environment This role works in office, R&D lab, and manufacturing floor environments Evening and weekend work may be required on an as needed basis 20-25% travel 85% production support 15% R&D benchtop work (formulation review /concept creation) Responsible for keeping workspace clean and organized (wash lab utensils and maintain ingredient inventory) Responsible for R&D shipments (UPS /FedEx) RequiredPreferredJob Industries Warehouse & Production

BlueSphere Bio is a Pittsburgh-based immunotherapy company developing novel T-cell therapies to treat individuals diagnosed with liquid and solid tumors. The established proprietary platform technologies in Neoantigen and tumor-specific TCR discoveries have provided a rich foundation for various TCR-T cell therapy pipelines and cancer vaccines to address unmet medical need in both blood and solid tumors. The Research & Development (R&D) organization at BlueSphere Bio aims to accelerate the translation of innovative research discoveries into new cancer therapeutic medicines through the collaboration with CMC, clinical and business development functions. Job Description We are seeking an Scientist I/Associate Scientist to join BlueSphere Bio's T-cell Receptor (TCR) Discovery team. The incumbent will use state-of-the-art instrumentation and techniques for the identification of TCRs that recognize minor histocompatibility antigens, as well as tumor-associated antigens and neoantigens. Additionally, she/he will work with a group of individuals developing a high-throughput platform that is able to isolate and identify rare antigen-specific T-cells from healthy and patient donor samples. Candidates interested in expanding their knowledge and gaining experience in cell-based (TCR-T) cancer therapies and drug discovery are highly-encouraged to apply. Duties and Responsibilities may include Process, characterize, and coordinate the genotyping of primary human blood/PBMC samples Apply high-throughput cell culture techniques for establishing co-cultures of primary T-cells with antigen-presenting cells Transduce and/or electroporate antigen-presenting cells with lentivirus or plasmid constructs Analyze T-cells and T-cell receptor function via flow cytometry Perform molecular biology techniques as the project requires for the cloning and detailed characterization of TCRs Develop assays for high-throughput screening of T-cells and TCR-antigen reactivity Maintain accurate sample and laboratory records Organize and conduct assigned studies with a high-degree of independence and attention to detail Present scientific results to peers and management during regularly scheduled lab meetings Required & Preferred Qualifications PhD in Cancer Biology, Immunology, Cell Biology, Molecular Biology, or related fields is required Hands-on research experience in an academic or industry setting is required A record of advancing projects, as evidenced by publications or patents is required In-depth knowledge of cellular biology is required Demonstrated work in cell culture techniques, including designing, setting up, and performing cell-based assays is required Experience in T-cell enrichment, expansion, and characterization is preferred Previous exposure to flow cytometry is required Experience in cell line development is required Experience in cellular transfection, lentivirus production and transduction is required Experience in assay/platform development is preferred Proficiency with analytical software packages, e.g., SnapGene, PRISM, FlowJo, and Excel is preferred The ability to adhere to timelines and milestones, in an organized manner, is required Excellent communication and presentation skills are preferred Demonstrated ability to independently identify issues and troubleshoot Physical and Mental Requirements You will be expected to occasionally (1% to 20% of the time): Climb stairs, ramps, ladders. Etc. Stoop/crouch by bending your legs or bending down/forward at the waist Reach by extending the hands/arms Lift objects from one level to another (30 lbs. or less) Carry objects (30 lbs. or less) Travel (up to 20%) You will be expected to frequently (21% to 50% of the time): Walk around the facility on foot Stand on your feet You will be expected to constantly (at least 51% of the time): Sit in a normal seated position BlueSphere Bio is an Equal Opportunity Employer (EOE) and offers employment opportunities to all qualified persons regardless of race, color, religion, sex, age, national origin or ancestry, physical or mental disability (except where physical or mental abilities are a bona fide occupational requirement), veteran status, marital status, familial status, sexual orientation, HIV-positive status, possession of the sickle cell trait, genetic characteristics, political views, and any other basis protected by federal, state or local laws.

Our mission at Duolingo is to develop the best education in the world and make it universally available. It's a big mission, and that's where you come in! At Duolingo, you'll join a team that cares about educating our users, experimenting with big ideas, making fact-based decisions, and finding innovative solutions to complex problems. You'll have limitless learning opportunities and daily collaborations with world-class minds - while doing work that's both meaningful and fun. Join our life-changing mission to develop education for our half a billion (and growing!) learners around the world. Read our blog to learn more. About the role... We are looking for a world-class language researcher with a proven track record in conducting research studies and analyzing large datasets. Our ideal candidate has expertise in language learning and/or assessment, along with extensive experience in language data analysis. At Duolingo, you will have an opportunity to apply your skills and knowledge to the world's largest language learning dataset. You'll work in a fast-paced, collaborative environment, where you see the immediate impact of your work on millions of learners worldwide. This job is based in Pittsburgh. :brain: You will... Lead or collaborate on research efforts that evaluate the effectiveness of Duolingo courses, from study design through data collection and analysis Analyze in-app data to gain insights that inform the learning experience Share your findings with both internal teams and external audiences, across various formats such as reports, white papers, and presentations Manage external research collaborations, guiding projects from proposal to final deliverables :check: You have... Research Expertise. You are an expert researcher in language assessment, acquisition, or processing, including quantitative methods and writing research reports. You have a Ph.D. in applied linguistics, second language acquisition, linguistics, cognitive science, or a related field. Advanced Data Analysis Skills. You have strong skills in statistics and data visualization. You are proficient in R or Python, and are able to quickly learn SQL or other data tools for handling large datasets. Innovative Problem-Solving Ability. You critically evaluate your work, proactively recommend improvements, and adapt to evolving priorities. Strong Communication and Collaboration. You have excellent interpersonal and communication skills. You collaborate well with others. Operational Focus. You are organized, efficient, and always looking for ways to improve workflows. :star: Exceptional candidates will have... Industry experience, especially in tech Strong publication record in high-profile academic journals A passion for language learning and knowledge of a language other than English We post a multi-level salary range for all of our roles. This is not inclusive of the rest of our awesome portfolio that includes equity compensation and world-class benefits. Our salary ranges are the same for all US locations. Your recruiter can share more details about the range for a specific level during the hiring process. The actual salary within the range is determined by many factors including but not limited to, skills, experience, education, and internal equity. Salary Range: $116,500-$157,600 USD Take a peek at how we care for our employees' holistic well-being with our benefits here. We will do everything we can within reason to make sure that your interview takes place in an environment that fairly and accurately assesses your skills. If you need assistance or accommodation, please contact accommodations@duolingo.com. Duolingo is proud to be an Equal Employment Opportunity employer. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. By applying for this position your data will be processed as per the Duolingo Applicant Privacy Notice. Sign up for job alerts here.

Arconic is currently in search of Staff Scientist, Optimization & Data Analytics to join our Arconic Technology Team based in New Kensington, PA At Arconic, we take pride in our work and our innovative products and technologies that advance sustainable solutions for a better world. We strive to create a safe, inclusive, and collaborative workplace with competitive benefits, development opportunities and a culture that values and rewards employees on all levels of the organization. Job Summary: The Staff Scientist, Optimization and Data Analytics is responsible for developing and supporting optimization, scheduling, and analytics applications across Arconic's processes including casting, rolling, extrusion, etc. This role is part of our Research & Development team and will provide technical expertise to support operations and lead multi-disciplinary projects focused on optimization of aluminum forming/fabrication processes. You have: (required) Master of Science (M.S.) Degree in Industrial Engineering, Mechanical Engineering, Electrical Engineering, Chemical Engineering, Operations Research, Computer Science, Statistics, Data Analytics, Data Science, or a related quantitative field with a focus in Optimization. Proficiency in general optimization with focus on Operations Research (Linear Programming, Combinatorial Optimization, Mixed-Integer Programming, Dynamic Programming). Intermediate programming skills with scripted programming languages such as (but not limited to) R, Python, and/or Matlab. Intermediate programming skills with computational optimization environments such as (but not limited to) CPLEX, Gurobi, and/or GLPK. Experience performing Exploratory Data Analysis (EDA), data manipulation/transformation, and applying data preprocessing techniques. Competency in classical statistical methods including hypothesis testing, generalized linear models, multivariate methods, and/or time series analysis. Employees must be legally authorized to work in the United States. Verification of employment eligibility will be required at the time of hire. Visa sponsorship is not available for this position. This position requires access to controlled technology, as defined in the Export Administration Regulations (15 C.F.R. §730, et seq.) and/or the International Traffic in Arms Regulations (ITAR). Authorizations from the relevant government agency may be required to meet export control compliance requirements. Preferred Qualifications Ph.D. Degree in Industrial Engineering, Mechanical Engineering, Electrical Engineering, Chemical Engineering, Operations Research, Computer Science, Statistics, Data Analytics, Data Science, or a related quantitative field with a focus in Optimization. Demonstrated experience in creating mathematical models in optimization programming language (OPL) using solvers such as GLPK and/or CPLEX. 3 or more years of experience in developing and applying optimization and/or scheduling solutions. 3 or more years of experience in industrial operations, logistics and supply chain, and/or manufacturing environments. Competency in relational databases such as (but not limited to) MS-SQL, PostgreSQL, MySQL, and/or SQLite. Proficiency in Heuristic Optimization methods such as (but not limited to) Genetic Algorithms, Simulated Annealing, Particle Swarm, and Ensemble Methods. Proficiency in Quality methods including Statistical Quality (Process) Control and measurement capability and analysis. Proficiency in using machine learning techniques to model complex systems. Competency in Reliability methods including parametric modeling, survival analysis, tolerance intervals, and event driven analytics. Ability to develop innovative and practical solutions to complex problems without direct technical supervision. Attention to detail within daily working habits. Strong written and verbal communication skills (technical writing and presentation). In this role, you will: Provide leadership and expertise in the application and utilization of advanced optimization and statistical tools and methods. Identify and translate industrial use cases into formal optimization problem statements with constraints and objectives. Convert optimization problem statements into detailed mathematical formulations and models. Program the mathematical models within algorithms using commercial and/or open-source computational tools and frameworks. Collaborate with Data Engineering resources to define appropriate data preprocessing, management, and storage needs supporting the optimization algorithms. Collaborate with IT and subject matter experts (SMEs) to provide wholistic solutions that solve manufacturing and/or business-oriented optimization and analytics challenges. Support R&D project planning activities by estimating costs and durations of optimization related activities. Regularly communicate details, benefits, and challenges of implementing optimization algorithms to stakeholders with varied backgrounds. Drive projects to completion and effectively communicate results through reports, patents, and/or presentations.

Sr Scientist Product Development This is a Research and Development (R&D) role focused on scoping and leading Productivity projects and generating cost savings ideas across Easy Ready Meals platform within the Hydration, Desserts, and Meals platform. We're looking for a talented individual to lead productivity initiatives working on beloved brands like OreIda, Devour Delimex, TGIF and Bagel Bites. The candidate will be leading and driving technical projects to meet business initiatives focused on productivity ,efficiency and brand maintenance across the entire frozen category. The Senior Scientist candidate should have a proven record of successfully leading, executing, and commercializing projects ranging in technical complexity with minimal guidance, and getting results in a variety of challenging and complex settings. The candidate should have experience leading business initiatives while exhibiting a collaborative approach and applying innovative solutions. Strong communication and collaboration skills are essential in this role, which operates in a dynamic and cross-functional environment. Key Components .Responsible for identifying, developing and commercializing new products to deliver cost savings. * The candidate will be scoping and/or driving highly technical and complex projects to meet the business' platform and Productivity objectives. * Opportunities will exist to lead/coach junior developers on projects. * Conduct feasibility assessments, prototype development, costing, supervision of factory trials, development of recipe and factory documentation, recipe and label development, technical approval, shelf-life assessment and technical support for initial factory production. * Manage multiple assignments projects concurrently and possess the ability to prioritize between a variety of business initiatives * Commercialization: Deep knowledge of commercialization processes and required activities as the technical/R&D lead. Ability to troubleshoot challenges. Knowledge of project management, basic finance and product costing * Collaboration: Work with cross functional teams acting as the lead product developer to drive execution across multiple projects * Communication: Provide updates to cross-functional teams; Identify hurdles and propose solutions * Demonstrate the ability to develop relationships with and coordinate commercialization activities across internal and external manufacturing facilities. * Lead and complete product testing, qualification, and commercialization in laboratory and production environments Recipe for Success - apply now if this sounds like you! * Bachelor's Degree (Master's is a Plus) - Food Science, Food Engineering, Chemistry, Chemical Engineering or related fields * Minimum of 5+ years Product Development and commercialization experience within a CPG or equivalent * Project management experience, technical expertise, and food science/processing knowledge * Experience with frozen foods preferred * Experience with identifying and executing margin improvement projects preferred. * Familiarity with Sensory testing methods and test design. * Excellent communication, influencing, project management and problem-solving skills * Highly motivated and able to multi-task varying degrees of complex projects * Willingness to travel up to 30%. Travel could include (but not limited to): to internal plants, co-manufacturers, and suppliers. * Experience delivering consumer centric, innovative solutions. * Demonstrated ability to influence, manage multiple projects concurrently with the ability to prioritize work, and solve problems effectively. * Brings an entrepreneurial spirit and growth mindset * Ability to manage through ambiguity Our Total Rewards philosophy is to provide a meaningful and flexible spectrum of programs that equitably support our diverse workforce and their families and complement Kraft Heinz' strategy and values. New Hire Base Salary Range: $89,800.00 - $112,200.00 Bonus: This position is eligible for a performance-based bonus as provided by the plan terms and governing documents. The compensation offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors Benefits: Coverage for employees (and their eligible dependents) through affordable access to healthcare, protection, and saving for the future, we offer plans tailored to meet you and your family's needs. Coverage for benefits will be in accordance with the terms and conditions of the applicable plans and associated governing plan documents. Wellbeing: We offer events, resources, and learning opportunities that inspire a physical, social, emotional, and financial well-being lifestyle for our employees and their families. You'll be able to participate in a variety of benefits and wellbeing programs that may vary by role, country, region, union status, and other employment status factors, for example: * Physical - Medical, Prescription Drug, Dental, Vision, Screenings/Assessments * Social - Paid Time Off, Company Holidays, Leave of Absence, Flexible Work Arrangements, Recognition, Training * Emotional - Employee Assistance Program , Wellbeing Programs, Family Support Programs * Financial - 401k, Life, Accidental Death & Dismemberment, Disability Location(s) Heinz Innovation Center Kraft Heinz is an Equal Opportunity Employer - Underrepresented Ethnic Minority Groups/Women/Veterans/Individuals with Disabilities/Sexual Orientation/Gender Identity and other protected classes. In order to ensure reasonable accommodation for protected individuals, applicants that require accommodation in the job application process may contact *********************** for assistance.

Carnegie Mellon University is a private, global research university that stands among the world's most renowned education institutions. With ground-breaking brain science, path-breaking performances, creative start-ups, big data, big ambitions, hands-on learning, and a whole lot of robots, CMU doesn't imagine the future, we invent it. If you're passionate about joining a community that challenges the curious to deliver work that matters, your journey starts here! The Biomedical Engineering (BME) Department at Carnegie Mellon University is renowned for its interdisciplinary approach to solving complex healthcare challenges. Located within CMU's College of Engineering, the department emphasizes the integration of engineering principles with biomedical sciences to address pressing medical and biological issues. The department is characterized by its focus on creating impactful technologies and therapies that improve patient care and advance biomedical innovation globally. Carnegie Mellon University is seeking a highly skilled and creative Research Scientist to lead Organ Biofabrication for the LIVE project, a multi-institutional initiative focused on developing transplantable bioprinted liver constructs. This encompasses the full pipeline of organ biofabrication-from computational design and advanced bioprinting to bioreactor maturation and in vivo validation. The LIVE project represents a bold and collaborative effort to overcome the most critical barriers in organ biofabrication and regenerative medicine. As part of the ARPA-H PRINT program, our goal is to develop a fully functional, immunocompetent, bioprinted human liver construct capable of clinical transplantation. Biofabrication is the heart of this mission, where computational design, advanced bioprinting, bioink formulation, bioreactor maturation, and in vivo validation converge to create a viable therapeutic organ. *Please provide a cover Letter outlining relevant experience and leadership philosophy Responsibilities: The Research Scientist will be responsible for technical management of this complex and multidisciplinary effort. This role is not only technical-it is strategic, collaborative, and deeply translational. The successful candidate will guide the development of novel software tools for organ blueprint generation and robotic print pathing, oversee the construction and operation of multi-modal bioprinting platforms, and lead the design of bioreactors capable of sustaining organ maturation for up to 30 days. In addition to technical execution, this role demands leadership in mentoring and team development. The Research Scientist will supervise and support graduate students, postdoctoral researchers, and technical staff across multiple institutions, fostering a culture of innovation, accountability, and scientific rigor. They will serve as a key liaison between CMU and partner organizations including the University of Washington, Mayo Clinic, FluidForm Bio, and the University of Pittsburgh, ensuring seamless integration of efforts across computational modeling, fabrication, and preclinical testing. The program culminates in the in vivo validation of bioprinted liver constructs in rodent and porcine models, including IND-enabling studies. The Research Scientist will play a central role in coordinating these studies, analyzing outcomes, and preparing regulatory documentation in collaboration with clinical and regulatory teams. This position offers a rare opportunity to provide senior leadership to a transformative initiative at the intersection of bioengineering, regenerative medicine, and clinical translation. The ideal candidate will bring not only technical excellence but also a passion for mentoring, a collaborative spirit, and a commitment to advancing the future of organ transplantation. Key Responsibilities: Lead development of liver-specific computational blueprints and bioslicer software for multi-arm robotic bioprinting. Oversee design and integration of advanced organ-scale perfusion bioreactors. Direct formulation and validation of ECM-based and photocrosslinkable bioinks. Manage construction and operation of multi-modal bioprinting systems, including 3D-ICE and light-pipe FRESH platforms. Coordinate in vitro efficacy testing and in vivo safety and functionality studies in rodent and porcine models. Collaborate with regulatory teams to support IND-enabling studies and documentation. Mentor graduate students, postdocs, and junior staff across CMU and partner institutions, providing technical guidance, career development support, and fostering a collaborative team culture. Qualifications: PhD in Biomedical Engineering, Biofabrication, Tissue Engineering, or related field. 5+ years of experience in organ bioengineering, bioprinting, or bioreactor development. Demonstrated success in leading or senior roles in collaborative research projects. Experience in computational modeling, imaging systems, and biosensors. Experience with in vivo models and surgical implantation techniques. Required Leadership & Mentoring Skills: Strategic Planning: Ability to execute a multi-phase technical roadmap aligned with program milestones. Team Leadership: Proven experience with interdisciplinary teams and fostering collaboration across institutions. Mentorship: Commitment to mentoring junior researchers, including PhD students and postdocs, with a focus on skill development, publication support, and career advancement. Project Management: Strong organizational skills to track deliverables, manage timelines, and ensure compliance with reporting requirements. Communication: Excellent written and verbal communication skills for technical reporting, presentations, and stakeholder engagement. Problem Solving: Ability to anticipate risks, develop mitigation strategies, and adapt to evolving technical challenges Opportunities: Lead a transformative effort to develop transplantable bioprinted liver tissue. Collaborate with world-class teams in biofabrication, regenerative medicine, and clinical translation. Contribute to IND-enabling studies and future first-in-human trials. Publish in high-impact journals and present at leading conferences Joining the CMU team opens the door to an array of exceptional benefits. Benefits eligible employees enjoy a wide array of benefits including comprehensive medical, prescription, dental, and vision insurance as well as a generous retirement savings program with employer contributions. Unlock your potential with tuition benefits, take well-deserved breaks with ample paid time off and observed holidays, and rest easy with life and accidental death and disability insurance. Additional perks include a free Pittsburgh Regional Transit bus pass, access to our Family Concierge Team to help navigate childcare needs, fitness center access, and much more! For a comprehensive overview of the benefits available, explore our Benefits page. At Carnegie Mellon, we value the whole package when extending offers of employment. Beyond credentials, we evaluate the role and responsibilities, your valuable work experience, and the knowledge gained through education and training. We appreciate your unique skills and the perspective you bring. Your journey with us is about more than just a job; it's about finding the perfect fit for your professional growth and personal aspirations. Are you interested in an exciting opportunity with an exceptional organization?! Apply today! Location Pittsburgh, PA Job Function Engineering, Research and Project Scientists Position Type Staff - Fixed Term (Fixed Term) Full Time/Part time Full time Pay Basis Salary More Information: Please visit “Why Carnegie Mellon” to learn more about becoming part of an institution inspiring innovations that change the world. Click here to view a listing of employee benefits Carnegie Mellon University is an Equal Opportunity Employer/Disability/Veteran. Statement of Assurance

BlueSphere Bio was founded to deploy its novel TCXpress technology to unlock the potential of personalized T cell therapy for the treatment of cancer by harnessing the unique specificity of each patient's T cells for the molecular fingerprint of each patient's cancer. Our trailblazing, proprietary TCXpress platform is an elegant, rapid approach that exploits the patient's immune defenses to attack their cancer specifically and is designed to leave normal tissues untouched, thereby reducing harmful side effects. The TCXpress platform and its implementation will deliver rapid, personalized T cell treatments for various cancer indications. Purpose The Scientist has a background in Synthetic Biology, Immunology, and Molecular biology to join our newly established group developing novel T cell products for adoptive cell-based immunotherapy of cancer. The position's primary role is in developing approaches to engineer T cell receptors in autologous or allogeneic primary human T cells. An ideal candidate will have a proven record of proficiency in Immunology and Molecular Biology. Knowledge in CRISPR/Cas9 and other non-viral gene-editing technologies is preferred. The candidate will join a diverse team with cross-functional interaction with development and discovery functions. The position requires excellent communication skills and the ability to work effectively in a goal-focused team environment. Duties and Responsibilities Establish methodologies for T cell gene modification and associated functional assays. Responsible for establishing efficient T cell receptor expression platforms in primary T cells using recombinant lentiviruses and CRISPR/ Cas9 technology Responsible for generation of high-titer recombinant lentiviruses, quality control of the lentiviral preparations, and generation of associated reagents Responsible for T cell immunology, including isolation, modification, expansion, and analysis of autologous and cryopreserved allogeneic primary T cell populations. Maintain accurate sample and laboratory records. Document activities in electronic notebook system, develop IP, publish and present in conferences Work closely with our development team to advance technology platforms and TCR candidates. Develop data packages and reports for internal corporate activities and regulatory submissions Present regularly at team meetings. Lead, train and mentor junior staff by example Other duties as assigned Qualifications and Work Experience Ph.D. in Immunology, Oncology, Molecular Biology, or related field with five years of postgraduate experience Mammalian Cell Culture: immortalized and primary adherent, and non-adherent cells T cell biology: Isolation and in vitro maintenance of PBMC, including CD4+ and CD8+ primary T cells. T cell activation, gene modification, and expansion for downstream functional assays, including TCR-dextramer binding, activation assays (proliferation, cell-based killing assays, analysis of cytokine secretion, etc.) Flow Cytometry: Strong background in multi-color flow cytometry [4 channel flow cytometry analysis preferred] of primary human immune cells and cell lines Molecular Cloning: vector design, restriction enzyme analysis of expression vectors, restriction independent cloning [In-Fusion and/or Gibson] Lentiviral technology: Understanding of LV packaging systems and LV expression vector components; experience in LV vector isolation and generation of recombinant lentivirus; lentiviral applications: transduction of immortalized and primary cells focusing on primary human PBMC and T cells Methods of non-viral gene delivery to target cells: transfection, electroporation/nucleofection, CRISPR/Cas9 with the focus on human PBMC and primary T cells Protein Biochemistry: western blotting, ELISA, isolation of proteins from mammalian cells, analytical protein purification using pull-down and immunoprecipitation techniques DNA/RNA isolation and nucleic acid technologies: PCR, RT-PCR, and Q-RTPCR; familiarity with NGS and RNA-Seq, genomic DNA PCR and Sanger sequencing; isolation of vector DNA (mini, midi, maxi, and mega preps), agarose gel electrophoresis and DNA/RNA fragment isolation from agarose gel Bacterial Culture: maintenance of bacterial cells, the transformation of the competent bacteria, isolation of vector DNA (mini, midi, maxi, and mega preps) Software: flow cytometry software, data analysis software (GraphPad Prism, Excel, etc.), Microsoft Office suite Organizational skills: experience in working in a multi-disciplinary team environment; resource management; ability to manage one's time within the individual, departmental, and corporate goals and timelines Physical and Mental Requirements You will be expected to occasionally (1% to 20% of the time): You will be expected to frequently (21% to 50% of the time): Lift objects from one level to another (30 lbs. or less) Carry objects (30 lbs. or less) Walk around the facility on foot Stand on your feet Travel up to 25% You will be expected to constantly (at least 51% of the time): Sit in a normal seated position

. . . . NEW OPPORTUNITY Translational Scientist: Immuno-Oncology (Title TBD) Do your skills include the following: Drug discovery and pre-clinical development? Oncology | Immuno-Oncology? PDX models, Humanized models, Xenograft models, etc.? Experience with biomarkers | | biomarker profiling | biomarker strategy? Would you like to learn more about this exciting new opportunity? Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************