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Senior principal scientist vs staff scientist

The differences between senior principal scientists and staff scientists can be seen in a few details. Each job has different responsibilities and duties. It typically takes 2-4 years to become both a senior principal scientist and a staff scientist. Additionally, a senior principal scientist has an average salary of $119,042, which is higher than the $93,941 average annual salary of a staff scientist.

The top three skills for a senior principal scientist include chemistry, drug discovery and java. The most important skills for a staff scientist are data analysis, research projects, and molecular biology.

Senior principal scientist vs staff scientist overview

Senior Principal ScientistStaff Scientist
Yearly salary$119,042$93,941
Hourly rate$57.23$45.16
Growth rate17%17%
Number of jobs85,334121,054
Job satisfaction--
Most common degreeBachelor's Degree, 52%Bachelor's Degree, 60%
Average age4141
Years of experience44

What does a senior principal scientist do?

A Senior Principal Scientist is focused on providing technical and scientific expertise in a specific field. They conduct quantitative and qualitative research to enhance existing products or develop new ones.

What does a staff scientist do?

The primary role of a Staff Scientist is to develop and manage scientific research projects with minimal supervision. They are also responsible for the technical and budgetary aspects of scientific research projects.

Senior principal scientist vs staff scientist salary

Senior principal scientists and staff scientists have different pay scales, as shown below.

Senior Principal ScientistStaff Scientist
Average salary$119,042$93,941
Salary rangeBetween $83,000 And $169,000Between $63,000 And $137,000
Highest paying CitySan Francisco, CARedwood City, CA
Highest paying stateCaliforniaCalifornia
Best paying companyAmazonEtsy
Best paying industryTechnologyTechnology

Differences between senior principal scientist and staff scientist education

There are a few differences between a senior principal scientist and a staff scientist in terms of educational background:

Senior Principal ScientistStaff Scientist
Most common degreeBachelor's Degree, 52%Bachelor's Degree, 60%
Most common majorChemistryChemistry
Most common collegeDuke UniversityDuke University

Senior principal scientist vs staff scientist demographics

Here are the differences between senior principal scientists' and staff scientists' demographics:

Senior Principal ScientistStaff Scientist
Average age4141
Gender ratioMale, 80.3% Female, 19.7%Male, 67.8% Female, 32.2%
Race ratioBlack or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.5% Asian, 26.5% White, 53.6% American Indian and Alaska Native, 0.1%Black or African American, 6.2% Unknown, 4.1% Hispanic or Latino, 9.4% Asian, 26.5% White, 53.6% American Indian and Alaska Native, 0.1%
LGBT Percentage8%8%

Differences between senior principal scientist and staff scientist duties and responsibilities

Senior principal scientist example responsibilities.

  • Manage stability coordination activities for market drug products in accordance to company and ICH guidelines.
  • Maintain a GMP & GLP laboratory & facility.
  • Provide documents and information of the CMC section for IND/NDA.
  • Assist FDA to validate contractor-supply data against the original source data.
  • Select appropriate biomarkers to determine mechanism of toxicity.
  • Identify several candidate biomarkers that are confirmed in internal experiments.
  • Show more

Staff scientist example responsibilities.

  • Lead efforts to replace a critical radioactive immunoassay with a non-radioactive format to measure clinical samples.
  • Manage clinical sample testing using MSD and ELISA in LIMS, including data review and approval using LIMS.
  • Assist in managing and maintenance of HPLC and Prep-HPLC systems to ensure maximum productivity for the process development group.
  • Manage pediatric dose development project, technology transfer project and alternate API supplier qualification project on budget and on schedule
  • Assist with RNA and DNA extractions from FFPE tissue and blood.
  • Supervise temps performing HPLC assays and validations during development and production campaigns under GMP conditions.
  • Show more

Senior principal scientist vs staff scientist skills

Common senior principal scientist skills
  • Chemistry, 8%
  • Drug Discovery, 7%
  • Java, 7%
  • Data Analysis, 6%
  • Clinical Development, 5%
  • Clinical Trials, 4%
Common staff scientist skills
  • Data Analysis, 9%
  • Research Projects, 7%
  • Molecular Biology, 5%
  • Next-Generation Sequencing, 4%
  • Statistical Analysis, 4%
  • RNA, 4%

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