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Research Scientist - CTRL Labs
Meta 4.8
Senior principal scientist job in Hartford, CT
Reality Labs at Meta is seeking Research Scientists with experience in product-focused machine learning and signal processing research to advance our pioneering work in neuromotor interfaces, which has grown out of the acquisition of CTRL-labs. We're building a practical interface drawing on the rich neuromotor signals that can be measured non-invasively via surface electromyography (EMG) with single motor neuron resolution. This technology could become one of the main pillars for interaction with virtual and augmented worlds.We are a multi-disciplinary team of researchers investigating the nature of human neuromotor signals, developing novel signal processing and machine learning methods to infer a user's intent, and creating novel interaction techniques and user experiences. Help us unleash human potential by removing the bottlenecks between user intent and action.
**Required Skills:**
Research Scientist - CTRL Labs Responsibilities:
1. Research and develop Deep Learning or other computational models
2. Design methods, tools and infrastructure to analyze and leverage rich multimodal data sets
3. Set technical direction for a project of 2-3 researchers and engineers
4. Help transition and deliver our work from research into product
5. Adapt standard machine learning methods to best leverage modern parallel environments (e.g. distributed clusters, multicore SMP, and GPU)
**Minimum Qualifications:**
Minimum Qualifications:
6. Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience
7. Ph.D. degree in Computer Science and Engineering, Electrical Engineering, Statistics/Mathematics
8. Experience with developing machine learning models at scale from inception to business impact
9. Programming experience in Python and hands-on experience with frameworks such as PyTorch
10. Exposure to architectural patterns of large scale software applications
11. Must obtain work authorization in the country of employment at the time of hire, and maintain ongoing work authorization during employment
**Preferred Qualifications:**
Preferred Qualifications:
12. Proven track record of achieving significant results as demonstrated by grants, fellowships, patents, as well as first-authored publications at peer-reviewed AI conferences (e.g. NeurIPS, CVPR, ICML, ICLR, ICCV, ACL, and ICASSP)
13. Demonstrated software engineer experience via an internship, work experience, coding competitions, or widely used contributions in open source repositories (e.g. GitHub)
14. Experience bringing machine learning-based products from research to production
**Public Compensation:**
$184,000/year to $257,000/year + benefits
**Industry:** Internet
**Equal Opportunity:**
Meta is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, transgender status, sexual stereotypes, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. We also consider qualified applicants with criminal histories, consistent with applicable federal, state and local law. Meta participates in the E-Verify program in certain locations, as required by law. Please note that Meta may leverage artificial intelligence and machine learning technologies in connection with applications for employment.
Meta is committed to providing reasonable accommodations for candidates with disabilities in our recruiting process. If you need any assistance or accommodations due to a disability, please let us know at accommodations-ext@fb.com.
$184k-257k yearly 60d+ ago
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Senior Applied Scientist (Pricing)
Coinbase 4.2
Senior principal scientist job in Hartford, CT
Ready to be pushed beyond what you think you're capable of? At Coinbase, our mission is to increase economic freedom in the world. It's a massive, ambitious opportunity that demands the best of us, every day, as we build the emerging onchain platform - and with it, the future global financial system.
To achieve our mission, we're seeking a very specific candidate. We want someone who is passionate about our mission and who believes in the power of crypto and blockchain technology to update the financial system. We want someone who is eager to leave their mark on the world, who relishes the pressure and privilege of working with high caliber colleagues, and who actively seeks feedback to keep leveling up. We want someone who will run towards, not away from, solving the company's hardest problems.
Our ******************************** is intense and isn't for everyone. But if you want to build the future alongside others who excel in their disciplines and expect the same from you, there's no better place to be.
While many roles at Coinbase are remote-first, we are not remote-only. In-person participation is required throughout the year. Team and company-wide offsites are held multiple times annually to foster collaboration, connection, and alignment. Attendance is expected and fully supported.
Data Science is an integral component of Coinbase's product and decision making process: we work in partnership with Product, Engineering and Design to influence the roadmap and better understand our users. With a deep expertise in experimentation, analytics and advanced modeling, we produce insights which directly move the company's bottom line.
Specifically, we're looking for a Senior Data Scientist to join our Retail Trading Team. In this role, you'll take charge of pricing experimentation and play a pivotal role in determining our pricing strategy: you'll spearhead testing design and analysis, find opportunities to improve engagement and our bottom line, and communicate your ideas to execs and leaders across the company.
*What you'll be doing (ie. job duties):***
* Act as a strategic partner and collaborate with cross-functional stakeholders to develop pricing vision, roadmap and priorities
* Design and develop pricing models and their evaluation framework to determine optimal pricing strategy
* Develop causal models to help isolate the impact of fee changes using experiments and observational data
* Initiate, develop, and maintain data pipelines and data models with outstanding craftsmanship
* Synthesize findings, and recommendations in a clear and concise manner and communicate to senior leadership
*What we look for in you (ie. job requirements):*
* Demonstration of our core cultural values: clear communication, positive energy, continuous learning, and efficient execution.
* PhD preferred, or a Master's degree in a field such as Economics or Statistics with 5+ years of relevant experience.
* Minimum 5 years of experience in pricing experimentation, data analysis and statistical modeling
* Strong proficiency in SQL, Python, R, or other programming languages used for data analysis and statistical modeling
* Ability to independently create plans for analytics projects and a track record of overseeing large / complex analytical projects spanning multiple teams
* Excellent communication and presentation skills with the ability to explain complex data and analysis to non-technical stakeholders.
* Strong attention to detail and ability to work under tight deadlines
*Nice to haves:*
* Experience applying causal inference techniques outside of controlled experiments
* Experience working at or on a Crypto-focused company or at a crypto exchange
Disclaimer: Applying for a specific role does not guarantee consideration for that exact position. Leveling and team matching are assessed throughout the interview process.
ID: G2462
\#LI-Remote
*Pay Transparency Notice:* Depending on your work location, the target annual salary for this position can range as detailed below. Full time offers from Coinbase also include bonus eligibility + equity eligibility**+ benefits (including medical, dental, vision and 401(k)).
Pay Range:
$180,370-$212,200 USD
Please be advised that each candidate may submit a maximum of four applications within any 30-day period. We encourage you to carefully evaluate how your skills and interests align with Coinbase's roles before applying.
Commitment to Equal Opportunity
Coinbase is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, sex, gender expression or identity, sexual orientation or any other basis protected by applicable law. Coinbase will also consider for employment qualified applicants with criminal histories in a manner consistent with applicable federal, state and local law. For US applicants, you may view the *********************************************** in certain locations, as required by law.
Coinbase is also committed to providing reasonable accommodations to individuals with disabilities. If you need a reasonable accommodation because of a disability for any part of the employment process, please contact us at accommodations***********************************
*Global Data Privacy Notice for Job Candidates and Applicants*
Depending on your location, the General Data Protection Regulation (GDPR) and California Consumer Privacy Act (CCPA) may regulate the way we manage the data of job applicants. Our full notice outlining how data will be processed as part of the application procedure for applicable locations is available ********************************************************** By submitting your application, you are agreeing to our use and processing of your data as required.
*AI Disclosure*
For select roles, Coinbase is piloting an AI tool based on machine learning technologies to conduct initial screening interviews to qualified applicants. The tool simulates realistic interview scenarios and engages in dynamic conversation. A human recruiter will review your interview responses, provided in the form of a voice recording and/or transcript, to assess them against the qualifications and characteristics outlined in the job description.
For select roles, Coinbase is also piloting an AI interview intelligence platform to transcribe and summarize interview notes, allowing our interviewers to fully focus on you as the candidate.
*The above pilots are for testing purposes and Coinbase will not use AI to make decisions impacting employment*. To request a reasonable accommodation due to disability, please contact accommodations[at]coinbase.com
$180.4k-212.2k yearly 60d+ ago
Applied Scientist 5
Oracle 4.6
Senior principal scientist job in Hartford, CT
We are looking for a Principal Applied Scientist to join our Security Engineering organization and help define the future of security operations for Oracle's SaaS ecosystem. This role offers a rare and high-impact opportunity to shape how next-generation detection, response, and threat defense will work across one of the largest enterprise cloud environments in the world.
As a Principal IC, you will architect and develop advanced ML and behavioral models that enable a new class of adaptive, intelligence-informed security capabilities. You will work directly with massive, noisy, and adversarial telemetry; build models that must operate at extreme scale; and pioneer approaches that transform how our analysts, detections, and automated systems understand attacker behavior.
In this role you will:
+ Invent new ways to detect and disrupt attackers
+ Build machine learning foundations for an AI-driven SOC
+ Influence the architecture of detection pipelines for years to come
+ Operationalize research at petabyte scale
+ Raise the scientific bar across the security organization
You will work closely with Detection Engineering, Red Team, Threat Intelligence, and Data Engineering to identify meaningful signal, reduce noise, validate hypotheses, and translate research into production systems.
**Responsibilities**
**Research & Modeling**
+ Develop novel ML models for anomaly detection, identity analytics, time-series/sequence analysis, graph modeling, and pattern mining across noisy, high-volume telemetry.
+ Design experiments, baselines, evaluation metrics, and scientific methodologies for threat detection problems.
+ Build prototypes, run experiments, analyze results, and iterate quickly.
**Data & System Understanding**
+ Work with massive, sparse, high-cardinality datasets (1.2PB/day+) to extract signal from noise.
+ Create data-efficient modeling approaches (self-supervision, embedding models, sampling strategies, feature extraction).
+ Design inference strategies that work under tight cost, performance, and real-time constraints.
**Cross-Functional Technical Work**
Collaborate with Detection Engineering, Data Engineering, Red Team, and Threat Intelligence to define problem statements, understand attack patterns, and interpret telemetry.
+ Provide scientific insights and deep technical guidance to engineering partners building pipelines and detections.
+ Translate research prototypes into production-ready designs with engineering teams.
**Scientific Rigor**
+ Establish strong modeling baselines, validation methodologies, ablation studies, and well-defined success criteria.
+ Document findings, methodologies, and recommended approaches clearly and reproducibly.
+ Maintain awareness of current academic and industry research; apply relevant advances appropriately.
**Required Qualifications**
**Technical Expertise**
+ Deep knowledge of ML approaches relevant to security:
+ anomaly detection
+ statistical modeling
+ representation learning / embeddings
+ sequence models (RNNs, Transformers)
+ graph-based analysis
+ clustering and outlier detection
+ Strong understanding of:
+ adversarial ML challenges
+ noisy/weak/no-label environments
+ data imbalance and cost-sensitive modeling
+ model explainability and operational constraints
**Hands-On Skills**
+ Expert programming in Python, SQL; comfortable with Spark, Beam, Flink, or similar distributed data systems.
+ Ability to rapidly prototype models and experiment with large datasets using PyTorch, TensorFlow, JAX, or similar.
+ Experience building models that run in production, including monitoring, drift detection, and model evaluation.
**Experience**
+ PhD or Master's in Computer Science, Machine Learning, Applied Mathematics, or equivalent experience.
+ 10+ years of industry or research experience applying ML to real-world problems.
+ Experience with security telemetry, cloud logs, SIEM/EDR/XDR analytics, identity data, fraud detection, or similar adversarial domains strongly preferred.
+ Demonstrated impact through deployed models, patents, publications, or widely adopted research outputs.
Disclaimer:
**Certain US customer or client-facing roles may be required to comply with applicable requirements, such as immunization and occupational health mandates.**
**Range and benefit information provided in this posting are specific to the stated locations only**
US: Hiring Range in USD from: $139,400 to $291,800 per annum. May be eligible for bonus, equity, and compensation deferral.
Oracle maintains broad salary ranges for its roles in order to account for variations in knowledge, skills, experience, market conditions and locations, as well as reflect Oracle's differing products, industries and lines of business.
Candidates are typically placed into the range based on the preceding factors as well as internal peer equity.
Oracle US offers a comprehensive benefits package which includes the following:
1. Medical, dental, and vision insurance, including expert medical opinion
2. Short term disability and long term disability
3. Life insurance and AD&D
4. Supplemental life insurance (Employee/Spouse/Child)
5. Health care and dependent care Flexible Spending Accounts
6. Pre-tax commuter and parking benefits
7. 401(k) Savings and Investment Plan with company match
8. Paid time off: Flexible Vacation is provided to all eligible employees assigned to a salaried (non-overtime eligible) position. Accrued Vacation is provided to all other employees eligible for vacation benefits. For employees working at least 35 hours per week, the vacation accrual rate is 13 days annually for the first three years of employment and 18 days annually for subsequent years of employment. Vacation accrual is prorated for employees working between 20 and 34 hours per week. Employees working fewer than 20 hours per week are not eligible for vacation.
9. 11 paid holidays
10. Paid sick leave: 72 hours of paid sick leave upon date of hire. Refreshes each calendar year. Unused balance will carry over each year up to a maximum cap of 112 hours.
11. Paid parental leave
12. Adoption assistance
13. Employee Stock Purchase Plan
14. Financial planning and group legal
15. Voluntary benefits including auto, homeowner and pet insurance
The role will generally accept applications for at least three calendar days from the posting date or as long as the job remains posted.
Career Level - IC5
**About Us**
As a world leader in cloud solutions, Oracle uses tomorrow's technology to tackle today's challenges. We've partnered with industry-leaders in almost every sector-and continue to thrive after 40+ years of change by operating with integrity.
We know that true innovation starts when everyone is empowered to contribute. That's why we're committed to growing an inclusive workforce that promotes opportunities for all.
Oracle careers open the door to global opportunities where work-life balance flourishes. We offer competitive benefits based on parity and consistency and support our people with flexible medical, life insurance, and retirement options. We also encourage employees to give back to their communities through our volunteer programs.
We're committed to including people with disabilities at all stages of the employment process. If you require accessibility assistance or accommodation for a disability at any point, let us know by emailing accommodation-request_************* or by calling *************** in the United States.
Oracle is an Equal Employment Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability and protected veterans' status, or any other characteristic protected by law. Oracle will consider for employment qualified applicants with arrest and conviction records pursuant to applicable law.
$85k-119k yearly est. 28d ago
Behavioral Health Research Scientist - Connecticut
Carebridge 3.8
Senior principal scientist job in Wallingford, CT
Behavioral Health Research Scientist Position specific details: This is a Health Research role where the successful hire will conduct data analysis, review and incorporation of relevant literature, collaborative project design, associated data collection activities including extracting and manipulating data, use statistical methods to analyze data and generate useful reports depicting trends in performance measures, conducting basic statistical analysis, report writing, and presenting results at committee meetings. This is not an IT role. Will also be responsible for understanding and assisting with updating performance measure methodology, including reporting and data requirements, and using quality improvement techniques to improve organizational and/or provider performance.
Hybrid 1: This role requires associates to be in-office 1-2 days per week, fostering collaboration and connectivity, while providing flexibility to support productivity and work-life balance. This approach combines structured office engagement with the autonomy of virtual work, promoting a dynamic and adaptable workplace. The ideal candidate will be within a reasonable distance of our Rocky Hill, CT or Wallingford, CT office.
Please note that per our policy on hybrid/virtual work, candidates not within a reasonable commuting distance from the posting location(s) will not be considered for employment, unless an accommodation is granted as required by law.
The Health Research Scientist - Connecticut creates statistical models to predict, classify, quantify, and/or forecast behavioral health (BH) outcomes. business metrics. Design modeling studies to address specific issues determined by consultation with internal and external partners.
How You Will Make an Impact:
* Prepares analytical data sets based on Medicaid claims and authorization data in support of modeling studies.
* Build, test, and validate statistical models.
* Publishes results and address constraints/limitations with high level partners.
* Proactively collaborates interdepartmentally to determine identified population segments and develop actionable plans to enable the identification of patterns related to quality, use, cost and other variables.
Minimum Requirement:
* Requires MS, MA, or PhD with concentration in a quantitative discipline such as statistics, cognitive science, economics, or operations research; a minimum of 3 years direct experience programming large, multi-source datasets with SAS required, and a minimum of 3 years in health care setting; or any combination of education and experience which would provide an equivalent background.
Preferred Skills, Capabilities, and Experiences:
* Experience in behavioral health, social studies, social work, psychiatry, or public health is strongly preferred.
* Intermediate to Advanced expertise with software such as SAS, SAS Enterprise Miner, Tableau or equivalents strongly preferred.
* Proven ability to design research studies and experience with data models, program evaluation, addressing data quality issues in study design, constructing robust and efficient analytical data sets strongly preferred.
* Significant experience analyzing claims data strongly preferred.
* The ability to present meaningful results to a business audience, to participate collaboratively in a team tasked to produce complex analyses on a rigorous schedule, to communicate with strong written and verbal communications skills, and to present to large multi-disciplinary audiences on a regular basis strongly preferred.
* Healthcare/managed care/insurance experience preferred.
* Experience with value-based payment models or attribution methodologies.
Please be advised that Elevance Health only accepts resumes for compensation from agencies that have a signed agreement with Elevance Health. Any unsolicited resumes, including those submitted to hiring managers, are deemed to be the property of Elevance Health.
Who We Are
Elevance Health is a health company dedicated to improving lives and communities - and making healthcare simpler. We are a Fortune 25 company with a longstanding history in the healthcare industry, looking for leaders at all levels of the organization who are passionate about making an impact on our members and the communities we serve.
How We Work
At Elevance Health, we are creating a culture that is designed to advance our strategy but will also lead to personal and professional growth for our associates. Our values and behaviors are the root of our culture. They are how we achieve our strategy, power our business outcomes and drive our shared success - for our consumers, our associates, our communities and our business.
We offer a range of market-competitive total rewards that include merit increases, paid holidays, Paid Time Off, and incentive bonus programs (unless covered by a collective bargaining agreement), medical, dental, vision, short and long term disability benefits, 401(k) +match, stock purchase plan, life insurance, wellness programs and financial education resources, to name a few.
Elevance Health operates in a Hybrid Workforce Strategy. Unless specified as primarily virtual by the hiring manager, associates are required to work at an Elevance Health location at least once per week, and potentially several times per week. Specific requirements and expectations for time onsite will be discussed as part of the hiring process.
The health of our associates and communities is a top priority for Elevance Health. We require all new candidates in certain patient/member-facing roles to become vaccinated against COVID-19 and Influenza. If you are not vaccinated, your offer will be rescinded unless you provide an acceptable explanation. Elevance Health will also follow all relevant federal, state and local laws.
Elevance Health is an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to age, citizenship status, color, creed, disability, ethnicity, genetic information, gender (including gender identity and gender expression), marital status, national origin, race, religion, sex, sexual orientation, veteran status or any other status or condition protected by applicable federal, state, or local laws. Applicants who require accommodation to participate in the job application process may contact ******************************************** for assistance.
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state, and local laws, including, but not limited to, the Los Angeles County Fair Chance Ordinance and the California Fair Chance Act.
$86k-124k yearly est. Auto-Apply 60d+ ago
Associate Research Scientist
Mindlance 4.6
Senior principal scientist job in Wallingford, CT
Position Description: The successful candidate will provide quantitative bioanalytical support using LC-MS/MS for a variety of high throughput in vitro ADME profiling assays. In this hands-on role, the candidate will perform sample analyses by mass spectrometry, and will review, interpret and report results. Instruments and software from various vendors including Sciex (Analyst) and Thermo (Excalibur) will be used along with custom internal data processing software to acquire data and process results. The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary.
Position Requirements: BS or MS in chemistry, with specialization in analytical chemistry preferred, along with 1 to 5 years of relevant pharmaceutical experience is required. Training or experience in mass spectrometry and separation science, as well as hands-on experience in quantitative LC-MS/MS analysis are desired. Proficiency in general computer software, including vendor specific instrument control and analysis tools, is required. Strong interpersonal and communication skills, both oral and written, are required as is commitment to working as a team player within a multifunctional organization. A working knowledge of allied disciplines such as computer science, lab automation, drug metabolism, pharmacokinetics and synthetic chemistry is helpful.
Qualifications
The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary.
LC-MS/MS analysis
BS or MS in chemistry
Additional Information
Thanks & Regards
Riya
************
$72k-98k yearly est. 2d ago
REACH Scientist - SPECTROMETRIST
The Kemtah Group
Senior principal scientist job in Naugatuck, CT
Job Title: Scientist- Mass Spectrometry Pay: $46-51/hour Zip Code: 06770 Job Type: Contract A Scientist- Mass Spectrometry job in Naugatuck, CT is available through Belcan. This is a contract opportunity with one of our key chemical clients.
Responsibilities;
* Mass Spectrometry skills for characterization of complex systems
* Mass Spectrometry - operation, execute general analysis as directed by Mass Spec head.
* REACH: European Regulatory compliance essential to do business in EU via Mass Spec experiments, interpretations.
* Administrative function including participation in Safety programs, performance culture, my HR, etc.
* Competency with GCMS, GCMSMS, LCMSMS essential.
Qualifications:
* Required Education & Experience: Ph.D. or equivalent, 5+ years' experience or BS/MS + 10 years' experience.
* Industrial Chemistry experience is a plus. Pharma experience
* Strong written and oral communication skills including live presentation.
* Advanced expertise in various types of Mass Spectrometry- Spectrometrist
* Basic expertise in Lubricant chemistry is a plus.
Belcan is an equal opportunity employer. Your application and candidacy will not be considered based on race, color, sex, religion, creed, sexual orientation, gender identity, national origin, disability, genetic information, pregnancy, veteran status or any other characteristic protected by federal, state or local laws.
$46-51 hourly 60d+ ago
Confections Formulation Scientist
Curaleaf 4.1
Senior principal scientist job in Webster, MA
Job Title: Confections Formulation Scientist Job Type: Full Time | Exempt Travel: Up to 50-75% to support our confection production facilities across the country
Who You Are:
You're a product development scientist with experience in confections, gummies, or candy formulation. You understand how hydrocolloids, pectin/gelatin systems, sugars, and emulsions work together to create consistent flavor, texture, and stability - and you know how to translate bench-top trials into scalable production. You bring deep knowledge of ingredient functionality, emulsions, and hydrocolloids, paired with the technical skill to scale formulations from the lab bench to full production. Whether running shelf-life studies, managing formulation data, or collaborating with cross-functional partners, you approach each challenge with precision, organization, and a problem-solving mindset. Above all, you're excited to push boundaries in the growing cannabis edibles space while upholding the highest standards of quality, safety, and compliance.
What You'll Do:
As a Confections Formulation Scientist, you'll play a central role in developing and scaling innovative cannabis-infused products. You'll conduct formulation trials, lead product testing, and support commercialization to bring new concepts to market. Your work will span from sensory evaluations to regulatory compliance, ensuring each product is safe, consistent, and high-quality. On any given day, you might be:
* Supporting the development, optimization, and scaling of cannabis-infused edibles through bench trials, pilot runs, and full-scale production
* Conducting sensory testing, shelf-life studies, and technical evaluations of texture, flavor, and stability using industry tools like viscometers and texture analyzers
* Maintaining SOPs, batch records, and technical documentation to streamline operations and support audits
* Ensuring compliance with GMP, food safety, labeling, and cannabis regulations, including coordinating third-party lab testing and interpreting results
* Managing formulation and ingredient data using MRP systems and formulation software for efficiency and accuracy
* Sharing data-driven insights that influence innovation, continuous improvement, and collaboration across the team
What You'll Bring:
* 5-8 years of experience in confectionery formulation and/or food manufacturing
* A bachelor's degree in Food Science, Chemistry, Food Chemistry, or a related field
* Hands-on experience in confection formulation and scale-up, with knowledge of production equipment
* Strong understanding of ingredient functionality, food chemistry, emulsions, and hydrocolloids to design stable formulations
* Familiarity with GMPs, food safety, and regulatory requirements, with direct experience in sensory testing and shelf-life evaluations
* Excellent communication and documentation skills, paired with attention to detail and strong organizational abilities
* Proficiency with Microsoft Office and formulation software
* Willingness to travel for trials, production support, and industry events
Even Better If:
* You have experience in the cannabis or hemp industry
* You're familiar with ERP/MRP systems for managing formulations and ingredient tracking
* You bring experience applying data science or analytics to product development
* You've supported R&D trials and helped scale products from concept to commercialization
Physical Requirements:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this Job, the employee is regularly required to stand, walk, sit, talk or hear, use hands to finger or feel, reach with hands and arms, and lift up to 25 lbs. The employee is occasionally required to climb and balance, stoop, kneel, crouch, or crawl and lift up to 50 lbs. This position requires close vision, distance vision, peripheral vision, depth perception and the ability to adjust focus.
Work Environment:
This position has allergen warnings, potential exposure to dust, pollen, and plant pathogens, requires exposure to cleaning solvents, such as high volumes of isopropyl alcohol, requires daily use of provided PPE, such as masks, hair nets, beard covers, respirators, boot covers, scrubs, non-slip shoes, and Tyvek suits as necessary, requires the ability to work in confined spaces, has exposure to loud noises, including but not limited to air compressors, packaging equipment, and alarms, has exposure to CO2 manufacturing procedures at OSHA approved CO2 levels and requires a high stress tolerance, adaptability, and flexibility. Ability to work in an ever-changing environment.
is remote and can be based anywhere within the United States._ **At Cardinal Health, we're developing the innovative products and services that make healthcare safer and more productive. Join a growing, global company genuinely committed to making a difference for our customers and communities.**
The Sr. Scientist, Scientific Operations, Real-World Evidence will have responsibility to design, and/or conduct innovative Real-World Data (RWD) and Real-World Evidence (RWE) projects for biopharmaceutical manufacturers. This individual will have subject matter expert (SME) in healthcare research, with knowledge and understanding of biomarkers, treatment patterns, measurement of treatment efficacy, and tolerability through chart review, EMR, or administrative claims databases. The position requires strong verbal and written communications skills that are necessary to translate research findings into peer-reviewed abstracts and manuscripts.
**_Responsibilities_**
+ Provide research expertise on RWD/RWE studies in a principal-investigator level scientific role
+ Work in a role that is heavily client-facing and consultative, providing expert guidance on study objectives and methodology to life sciences partners
+ Support the generation of high-quality real-world research studies using chart review, administrative claims, and electronic medical record methods/data
+ Support the business development process by serving as an SME for healthcare research in terms of design, proposal development, protocol development, analysis, and reporting
+ Proactively address complex analytical issues with research analytics and research operations team members during the conduct of a study
+ Work in a fast-paced and accountable environment engaging on multiple projects with multiple manufacturers at the same time
+ Interact with internal and/or external leaders, including senior management
+ Guide members of multiple research teams into consensus in sensitive situations while maintaining positive relationships
+ Write and review research study concepts, protocols, statistical analysis plans, table shells, and reports (must have substantial writing and communication skills)
+ Determine appropriate research methods and data sources to deliver high-value and quality real-world research to pharmaceutical manufacturers
+ Communicate effectively and professionally with pharmaceutical RWE customers
+ Generate and review empirical abstracts and publications
+ Prepare and review responses to proposal requests for RWE/HEOR projects
+ Prepare RWE/HEOR data as background materials for discussion with pharmaceutical customers
+ Ability to provide excellent customer service when delivering work on projects
+ Develop expertise in RWE/HEOR through publications and presentations of scientific research
+ Collaborate with RWE team, as required, to compile evidence required to execute projects for pharmaceutical clients
**_Qualifications_**
+ Education: MA/MS or PhD in epidemiology, health services research, or similar field, highly preferred
+ Ability to travel a few times during the year for conferences and client meetings
+ 4+ years of relevant working experience (during employment and/or while obtaining advanced degree); 1 year in the pharmaceutical/medical industry within a pharmaceutical company or a pharmaceutical consulting company, highly preferred
+ Knowledge of RWE and HEOR and its application to specialty drugs within the US market
+ Leadership skills and problem-solving capability
+ Demonstrated success implementing projects, including engagement with key stakeholders, with high degree of autonomy
+ Excellent written and verbal communication skills, and presentation skills
+ Ability to travel domestically, as needed
**Anticipated salary range:** $123,400 - $141,000
**Bonus eligible:** Yes
**Benefits:** Cardinal Health offers a wide variety of benefits and programs to support health and well-being.
+ Medical, dental and vision coverage
+ Paid time off plan
+ Health savings account (HSA)
+ 401k savings plan
+ Access to wages before pay day with my FlexPay
+ Flexible spending accounts (FSAs)
+ Short- and long-term disability coverage
+ Work-Life resources
+ Paid parental leave
+ Healthy lifestyle programs
**Application window anticipated to close:** **01/19/26** *if interested in opportunity, please submit application as soon as possible.
_**The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate's geographical location, relevant education, experience and skills and an evaluation of internal pay equity._
_Candidates who are back-to-work, people with disabilities, without a college degree, and Veterans are encouraged to apply._
_Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal_ _Opportunity/Affirmative_ _Action employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law._
_To read and review this privacy notice click_ here (***************************************************************************************************************************
$123.4k-141k yearly 8d ago
Formulation Scientist
SCA Pharmaceuticals
Senior principal scientist job in Windsor, CT
SCA Pharmaceuticals is a dynamic rapidly growing company consisting of passionate individuals who believe in our mission of providing high quality medications that are critical in saving and sustaining human life. SCA Pharma is an FDA 503B outsourcing facility providing customized medications for hospitals and healthcare facilities across the United States. We do this through unyielding quality, safety and integrity, our commitment to accountability and ownership, teamwork and problem solving.
Summary:
The Formulation Scientist is responsible for developing and optimizing sterile injectable formulations for 503B compounding operations. This role focuses on formulation design, scale-up, and technical support to ensure stability, manufacturability, and compliance with FDA and cGMP requirements. Key responsibilities include conducting compatibility and stability studies, preparing technical documentation for 503B compliance, and collaborating with cross-functional teams to support product development and scale-up. The Formulation Scientist provides formulation expertise during investigations and regulatory inspections as needed and contributes to new product initiatives and lifecycle management.
Requirements
Essential functions:
Lead the design and development of pharmaceutical formulations for sterile injectables in compliance with FDA and cGMP standards.
Scale up lab formulations to commercial production, ensuring reproducibility and robust results. Support evaluation of technologies and processes to improve product performance.
Conduct compatibility studies using stability testing and chromatographic techniques.
Develop and optimize formulations to ensure stability and manufacturability.
Evaluate and select appropriate pharmaceutical API and excipients based on functionality, compatibility, and regulatory status.
Provide formulation support to troubleshoot manufacturing challenges.
Prepare formulation development reports and technical documentation to support 503B compliance.
Provide technical support during regulatory inspections as needed.
Support investigations and provide formulation input for deviations and change controls.
Collaborate with cross-functional teams to support product development and scale-up.
Provide formulation input for new product development initiatives.
Additional responsibilities as assigned.
Required Qualifications & Experience:
Master's degree in biology, chemistry, engineering, or related field-or equivalent experience
5+ years in pharmaceutical formulation development; experience in sterile compounding or aseptic manufacturing preferred
Strong knowledge of formulation science and excipients for sterile injectables
Experience with sterile and compounded dosage forms
Working knowledge of cGMP compliant Quality Systems and FDA regulations including 21 CFR Part 503B, USP compounding standards (795, 797, 800), and 21 CFR Parts 210 and 211
Proficiency with Quality by Design (QbD) principles and Design of Experiments (DOE) methodologies
Strong project management, leadership and problem-solving abilities
Proven ability to communicate and collaborate across teams
Proficient in MS Office and statistical software
Desired Knowledge, Skills, and Abilities:
Experience with regulatory documentation and technical writing for 503B compliance.
Understanding of risk management principles and failure mode effects analysis (FMEA).
Ability to communicate complex scientific concepts to diverse audiences.
Must be well organized and detail-oriented with proven initiative and self-starter skills.
SCA Pharma is an equal opportunity employer (Minorities/Females/Disabled/Veterans). We recruit, employ, train, compensate, and promote without regard to race, religion, creed, color, national origin, age, gender, sexual orientation, marital status, disability, veteran status, or any other basis protected by applicable federal, state or local law.
$79k-114k yearly est. 49d ago
Scientist II/Senior Scientist I, Biologics Generation Group
Mygradjob
Senior principal scientist job in Worcester, MA
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases.
AbbVie employs approximately 28,000 people worldwide and markets medicines in more than 170 countries.
Job Description
APPLY HERE!!! *****************************************************************************
Description
Abbvie has an opening for a Scientist II/SeniorScientist I, Biologics Generation Group at our Bioresearch Center in Worcester, MA. The Biologics Generation Group collaborates with drug discovery project teams across all Abbvie therapeutic areas including Oncology, Immunology, and Neurology. The ideal candidate will effectively work in cross-functional teams to produce and characterize biopharmaceutical products, such as fully-human monoclonal antibodies, and novel multi-specifics including dual variable domain immunoglobulin (DVD-Ig™). They will have expertise in protein analytical techniques such as mass spectrometry, chromatography, differential scanning calorimetry, etc.
Key Responsibilities:
Develop advanced analytical methods to characterize biologics using mass spectrometry and UHPLC
Design and execute assays for high throughput drug-like property assessment of biologics
Impact projects through protein production and screening of recombinant biopharmaceutical candidates in high throughput
Demonstrate scientific excellence, work ethic, and dedication to team and project goals
Work collaboratively in a matrix with project teams and members of the Biologics Generation Group to drive innovation and deliver novel therapies to our patients
Develop productive collaborations and communication with other groups, across therapeutic areas
Qualifications
Bachelor's degree in related discipline with 7 or more years of experience or Master's degree with 5 or more years of experience
Expertise in protein analytical techniques for the assessment of drug-like properties of biopharmaceutical candidates
Experience maintaining instrumentation and method development for protein and peptide mass spectrometry
Experience working with automated laboratory workflows and instruments such as Hamilton and Tecan liquid handlers
Experience with transient protein expression and purification
Experience with assays such as ELISA and flow cytometry
Preferred Qualifications:
PhD in related discipline with no experience necessary
Additional Information
All your information will be kept confidential according to EEO guidelines.
$73k-113k yearly est. 2d ago
Scientist III - Microbiologist, EM Focus, Analytical Sciences Microbiology - FSP
Parexel 4.5
Senior principal scientist job in Hartford, CT
We are looking to fill a microbiologist position (environmental monitoring focus) working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients in Rahway, NJ. This position offers full benefits, sick time, 401K, paid holidays, and paid time off. This position does not offer sponsorship.
**Qualifications**
+ Bachelor's degree required; concentration in a scientific or applied discipline strongly preferred
+ A minimum of two years of experience in pharmaceutical microbiology related position required (occasional overtime)
**Required Skills and Experience**
+ Experience in working in a GMP Pharmaceutical environment with specific experience environmental monitoring
+ Proven technical writing skills (SOPs, protocols)
**Responsibilities**
ENVIRONMENTAL MONITORING
+ Proficiency in the pharmaceutical microbiology laboratory workflow for EM collection and testing, reporting and trending
+ Sampling EM rooms, surface and air
+ Collection and testing water samples
+ Weekly water trends- visually to be able to report back to the source area
+ Equipment responsibilities with metrology oversight, automation, etc
+ MODA USE
+ Responsible for writing annual reports
+ Responsible for writing trend reports
+ Able to clearly interpret adverse vs desirable data
+ Mold investigations and studies
+ PSIM work
+ Biological indicator analysis and certification
+ Disinfection studies where appropriate
+ Critical thinking with data
MICROBIOLOGICAL PRODUCT ANALYSIS
+ Analyze samples and compile meaningful data
+ Perform Investigations and prepare/respond to CAPA
+ Review, revise Test Procedures/Standard Operating Procedures
+ Ad Hoc work
+ Rotational on-call assignments for responding to alarms
MICROBIOLOGICAL ACTIVITIES Include (but not limited to):
+ Receive, verify & Log in samples
+ Return templates and shipping paperwork when and where appropriate
+ Prepare and ship materials offsite for ID/testing (when applicable)
+ Stock culture management and quality control of same
+ Biological indicator management
+ Bioburden testing
+ Water sampling
+ Microbiological media management and quality control of same
+ Sterilization activities
+ Research experiments as deemed appropriate by client management
+ Method Validation/Qualification
+ Other microbiological activities
CALIBRATIONS:
+ Execute "Before-Use" calibrations prior to performing testing
+ Review calibration data within the ELN
+ Prepare and submit equipment for calibrations (offsite or onsite)
+ Complete calibration/PM paperwork
GMP ACTIVITIES:
+ Prepare GMP documentation as requested by management
+ Perform laboratory sanitizations and ensure cleanliness of laboratory workspace
+ Perform equipment sanitizations (incubators / hoods / refrigerators)
+ Purchase supplies (GMP)
+ Prepare and send documents to Records Center
INVESTIGATIONS:
+ Initiate, facilitate, and perform Investigations and NOEs (Notice of Event-NOE) for Environmental samples [NOE for Microbiological Environment Event (MEN)]
+ Inform management of non-conforming events
AUDITS:
+ Participate in audits (Regulatory, In-house, Corporate)
+ Participate in self-inspections and safety inspections
+ Retrieve data when requested by Microbiology management
TRAINING:
+ Complete assigned training when required
+ Ensure training is complete prior to performing tasks
+ The role is intended to be a 40-hour-per-week position.
**About Parexel**
Parexel FSP includes the CMC Operations group. We provide pharmaceutical and biopharmaceutical companies with qualified and talented technical professionals to support the development and delivery of new therapies.
For results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement.
Come join us!
\#LI-DK1
EEO Disclaimer
Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
$89k-116k yearly est. 13d ago
Consultant, Life Sciences Consulting
Norstella
Senior principal scientist job in Hartford, CT
**About The Dedham Group:** We set out to develop a health care innovation organization that could separate the background "noise" from what warrants investment in our highly complex, rapidly evolving marketplace lacking transparency to enable our pharmaceutical and biotech clients to make better decisions and flourish.
Today, ten years later, we are the preeminent U.S. market access oncology and specialty strategy partner, grounded in the structure and logic of the strategy consulting discipline, bolstered by our robust data set continuously enriched via our unequaled specialty access panel of the most highly influential access and value influencers in the U.S.
With a unique staffing model of highly structured and collaborative creative thinkers akin to an oncology and specialty think tank, we have increasingly come to be viewed as an influencer in our industry. At the interface of clinical, economic, and operational evolving needs, the Dedham Group has become the go-to resource for addressing the challenges faced by the world's leading life sciences organizations.
Now, The Dedham Group is proud to be a part of Norstella (*************************** . Norstella is a premier and critical global life sciences data and AI solutions provider dedicated to improving patient access to life-saving therapies. Norstella supports pharmaceutical and biotech companies across the full drug development lifecycle - from pipeline to patient. Our mission is simple: to help our clients bring therapies to market faster and more efficiently, ultimately impacting patient lives.
Norstella unites market-leading brands - Citeline, Evaluate, MMIT, Panalgo, Skipta and The Dedham Group and delivers must-have answers and insights, leveraging AI, for critical strategic, clinical, and commercial decision-making. We help our clients:
- Accelerate the drug development cycle
- Assess competition and bring the right drugs to market
- Make data driven commercial and financial decisions
- Match and recruit patients for clinical trials
- Identify and address barriers to therapies
Norstella serves most pharmaceutical and biotech companies around the world, along with regulators like the FDA, and payers. By providing critical proprietary data supporting AI-driven workflows, Norstella helps clients make decisions faster and with greater confidence. Norstella's investments in AI are transforming how data is consumed and decisions are made, disrupting inefficient legacy workflows and helping the industry become more efficient, innovative, and responsive to patient needs.
**About the Consultant role:**
As a Consultant, you will works closely within teams and clients to lead primary and secondary research, develop logical and insightful qualitative and quantitative analyses, and create innovative and effective recommendations.
**To succeed in this role, you will:**
+ Contribute to day-to-day management of 3+ projects, guide overall strategic direction and delegation of tasks to team members, parachute where needed across workstreams to streamline execution
+ Be responsible for timely and successful project execution
+ Provide direct feedback to junior staff to support career development goals
+ Support client relationships, fulfill client requests and begin to forecast future project needs
+ Aid in developing project proposals and capabilities decks to support overall firm development
+ Communicate clearly with senior project managers on project responsibilities, progress, alignment to timeline, and bandwidth of teams
+ Other duties as assigned
**Requirements**
+ Bachelor's or advanced degree with a life science focus
+ 4+ years life sciences Market Access consulting
+ Superior skills in using MS Office (particularly PowerPoint and Excel)
+ Excellent oral and written communication skills
+ Strong collaboration skills; must be a team player
+ Strong attention to detail
+ Expert knowledge of provider and payer dynamics within healthcare, specifically within oncology, cellular therapy / CAR-T, immunology, neurology / CNS, and/or other rare diseases / specialty therapeutics
**The Guiding Principles For Success At Norstella**
**01: Bold, Passionate, Mission-First**
We have a lofty mission to Smooth Access to Life Saving Therapies and we will get there by being bold and passionate about the mission and our clients. Our clients and the mission in what we are trying to accomplish must be in the forefront of our minds in everything we do.
**02: Integrity, Truth, Reality**
We make promises that we can keep, and goals that push us to new heights. Our integrity offers us the opportunity to learn and improve by being honest about what works and what doesn't. By being true to the data and producing realistic metrics, we are able to create plans and resources to achieve our goals.
**03: Kindness, Empathy, Grace**
We will empathize with everyone's situation, provide positive and constructive feedback with kindness, and accept opportunities for improvement with grace and gratitude. We use this principle across the organization to collaborate and build lines of open communication.
**04: Resilience, Mettle, Perseverance**
We will persevere - even in difficult and challenging situations. Our ability to recover from missteps and failures in a positive way will help us to be successful in our mission.
**05: Humility, Gratitude, Learning**
We will be true learners by showing humility and gratitude in our work. We recognize that the smartest person in the room is the one who is always listening, learning, and willing to shift their thinking.
**Benefits**
+ Medical and prescription drug benefits
+ Health savings accounts or flexible spending accounts
+ Dental plans and vision benefits
+ Basic life and AD&D Benefits
+ 401k retirement plan
+ Short- and Long-Term Disability
+ Paid parental leave
+ Paid time off
**_Please note- all candidates must be authorized to work in the United States. We do not provide visa sponsorship or transfers. We are not currently accepting candidates who are on an OPT visa._**
_The expected base salary for this position ranges from $150,000 to $175,000. It is not typical for offers to be made at or near the top of the range. Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, where applicable, licensure or certifications obtained. Market and organizational factors are also considered. In addition to base salary and a competitive benefits package, successful candidates are eligible to receive a discretionary bonus._
_All legitimate roles with Norstella will be posted on Norstella's job board which is located at norstella.com/careers. If a role is not posted on this job board, a candidate should assume the role is not a legitimate role with Norstella. Norstella is not responsible for an application that may be submitted by or through a third-party and candidates should proceed with extreme caution if a third-party approaches them about an open role with Norstella. Norstella will never ask for anything of value or any type of payment during or as part of any recruitment, interview, or pre-hire onboarding process. If you are aware of or have reason to believe a job posting purportedly for a role with Norstella is fraudulent or otherwise not authorized by Norstella, please contact the Company using the following email address:_ _[email protected]_ _._
_The Dedham Group is an equal opportunity employer. All Job applicants will receive equal treatment regardless of race, creed, color, religion, alienage or national origin, ancestry, citizenship status, age, physical or mental disability or handicap, medical condition, sex (including pregnancy and pregnancy-related conditions), marital or domestic partner status, military or veteran status, gender, gender identity or expression, sexual orientation, genetic information, reproductive health decision making, or any other protected characteristic as established by federal, state, or local law._
_Sometimes the best opportunities are hidden by self-doubt. We disqualify ourselves before we have the opportunity to be considered. Regardless of where you came from, how you identify, or the path that led you here- you are welcome. If you read this job description and feel passion and excitement, we're just as excited about you._
Norstella is an equal opportunity employer. All job applicants will receive equal treatment regardless of race, creed, color, religion, alienage or national origin, ancestry, citizenship status, age, physical or mental disability or handicap, medical condition, sex (including pregnancy and pregnancy-related conditions), marital or domestic partner status, military or veteran status, gender, gender identity or expression, sexual orientation, genetic information, reproductive health decision making, or any other protected characteristic as established by federal, state, or local law.
$150k-175k yearly 60d+ ago
Research Scientist
Wesleyan Local Food Co-Op
Senior principal scientist job in Middletown, CT
Under the direction of Dr. Tsampikos Kottos, the Research Scientist will be working on the research effort on “AI-Guided Self-Organization: Tailoring Disorder to Shape Complex Nonlinear Dynamics”. The project aims to combine modern machine learning with physical insight and high-throughput automated experiments to enable unprecedented AI-assisted design and control of complex self-organization. Guided by studies with universal physical models, the effort will develop new techniques for physics-guided inverse design and control. The theoretical activity will be complemented with experimental proof-of-principle concepts using networks of electronic oscillators. These will function as a training and testing ground to enable universal techniques for AI-based design and control of complex systems.
Responsibilities include:
Supervise graduate and undergraduate students
Manuscript preparation and editing and conference presentations.
Assisting in grant preparation and grant applications
Other duties as assigned
This is an on-campus position and the position is approved for two years with the potential to extend another year.
Information about the WTICS group can be found at ************************************
Minimum Qualifications
PhD in Physics, Applied Mathematics, Electrical or Mechanical Engineering or related field.
Knowledge of theory of metamaterials.
Knowledge of coupled mode theory.
Knowledge of nonlinear dynamics.
Knowledge of machine learning.
Preferred Qualifications
Experience in developing proof-of-principle RF and microwave experimental platforms that allow validation of the theoretical concepts.
Demonstrated commitment to work within a diverse environment and interact openly with individuals of different backgrounds.
Position is open until filled. As part of your application, please upload a cover letter and resume.
Compensation: $61,300.00 - $66,800.00Work Location: On Campus
All offers to external applicants are contingent on the candidate's completion of a pre-employment background check screening to the satisfaction of Wesleyan University.
Wesleyan University, located in Middletown, Connecticut, does not discriminate on the basis of race, color, religious creed, age, gender, gender identity or expression, national origin, marital status, ancestry, present or past history of mental disorder, learning disability or physical disability, political belief, veteran status, sexual orientation, genetic information or non-position-related criminal record. We welcome applications from women and historically underrepresented minority groups. Inquiries regarding Title IX, Section 504 or any other non-discrimination policies should be directed to Vice President for Equity and Inclusion, Title IX and ADA/504 Coordinator.
Wesleyan University complies with the Clery Act and maintains records of campus crime statistics and security policies. Copies of Wesleyan University's Clery Act Report are available on request and online at *************************************************
Experience is taken into consideration in the determination of salary offers. For more information visit **********************************************************************
Wesleyan offers a broad range of employee benefits and development opportunities, including comprehensive group insurance plans, wellness programs and incentives, generous paid time off and retirement plans, flexible work schedules, employee and dependent tuition programs for those who qualify.
Detailed information on the benefits of working at Wesleyan is located at: ***********************************************************
$61.3k-66.8k yearly Auto-Apply 60d+ ago
Associate Scientist
The Jackson Laboratory 4.3
Senior principal scientist job in Farmington, CT
The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders.
The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab.
Key Responsibilities & Essential Functions
Platform Leadership: Serve as the Xenium Platform Lead and Subject Matter Expert (SME), providing guidance and support to end-users and the broader scientific community.
Project Management & Execution: Coordinate the full lifecycle of Xenium projects, including managing sample submission and receiving, providing service quotations, executing experiments, and ensuring final data quality control (QC).
System Maintenance: Oversee instrument management, including maintaining the Xenium instrument, managing stock and inventory, and performing advanced troubleshooting of equipment and assays.
Process Optimization & Development: Drive the continuous improvement of the platform by optimizing existing workflows and developing new spatial genomics capabilities and technologies.
Scientific Awareness: Stay current with the newest developments in the spatial genomics field and effectively communicate technological updates to the team and research community.
Meticulous Documentation: Maintain excellent documentation standards, including comprehensive lab notebooks, SOPs, error/work logs, metadata, and sample information.
Stakeholder Communication: Ensure seamless communication with end-users, vendors, colleagues, and managers to coordinate and successfully complete all Xenium projects.
Knowledge, Skills, and Abilities
Required
Education: Master's degree (M.S.) in Biology, Molecular Biology, or a related scientific field.
Experience: 2-4 years of experience in a core facility or industry setting.
Molecular & RNA Biology: Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays.
Imaging-Based Spatial Genomics Expertise: Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seq FISH.
Technical Breadth: Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seq FISH).
Sample Handling: Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques.
Documentation: Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN).
Operational Skills: Proven project and lab management experience, including managing stock, inventory, and instrument uptime.
Soft Skills: Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups.
Preferred
Education: Ph.D. preferred
Single-Cell Experience: Hands-on experience with single-cell technologies (e.g., 10x Chromium, smart-seq, split-and-pool methods).
Biopharma Industry Experience: Preferred experience working in an industrial setting, such as the biotechnology or pharmaceutical sector, demonstrating familiarity with industry-standard workflows and requirements.
Histology Expertise: Experience in histopathology.
Development: Proven track record in technology development or assay optimization.
Pay Range: $65,018 - $101,081, pay is determined by experience
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit *********** .
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
$65k-101.1k yearly Auto-Apply 7d ago
Purification Scientist III
Us Tech Solutions 4.4
Senior principal scientist job in Worcester, MA
**Top 3-5 skills, experience or education required** 1. Strong biological scientific understanding. 2. Experience with chromatography and filtration for biologics purification 3. Experience with bioanalytical assays and methods preferred Years of experience/education and/or certifications required: PhD. - Chemical Engineering, Biotechnology, Biochemistry, or Chemistry with 0-2 yrs. Experience or MS with 4-6 yrs. Experience
**Nice to have (but not required)**
- PhD. - Chemical Engineering, Biotechnology, Biochemistry, or Chemistry with 0-2 yrs.
- Internship or corporate experience
- Laboratory hands on skills
**Job Description**
This position is in the Biologics Purification Development team of the Product Development Science & Technology department at Bioresearch Center. The candidate will be involved with all aspects of **protein purification and protein chemistry** to support biopharmaceutical process development.
**Responsibilities include:**
- Execute high throughput scale down robotic purification as part of early and late stage process development, viral clearance, process characterization, and continuous **process improvement** studies.
- Perform data acquisition and analysis, and documentation in electric lab notebooks.
- Will develop economical, robust steps for recovering the target protein from bioreactor harvests using chromatography, filtration, and other separation techniques; developing downstream purification processes to be transferred to manufacturing; and perform laboratory scale process characterization studies.
- Perform various bioanalytical assays, including HPLC, ELISAs and SDS-PAGE, to aid in rapid process development.
- The candidate must possess strong written, oral, and collaborative skills in order to effectively communicate experimental procedures and results.
- As appropriate, the candidate may supply technical support for pilot and/or GMP manufacturing of clinical materials.
- Execute new technology/innovation evaluation for **purification process.**
About US Tech Solutions:
US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit ************************
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
$77k-114k yearly est. 2d ago
Facility Scientist 2
Uconn Careers
Senior principal scientist job in Storrs, CT
The University of Connecticut Proteomics and Metabolomics Facility (UConn PMF, https://proteomics.uconn.edu) is hiring a Facilities Scientist 2 to assist the Facility Director with quantitative proteomics analysis using advanced mass spectrometry instrumentation and leading bioinformatics software. The PMF opened in 2017 as the University of Connecticut's first proteomics-focused and full service mass spectrometry core facility, and is housed administratively within the Center for Open Research Resources and Equipment (https://core.uconn.edu). UConn PMF in Storrs has outstanding instrumentation (2 Waters TOFs, 2 Thermo Scientific Orbitraps, and a Bruker tims TOF HT) and is expanding its footprint to the UConn Health medical research campus (Farmington, CT) in Summer 2025 with a brand new Bruker tims TOF Ultra 2 mass spectrometer. UConn PMF exists to provide fully customized analysis to more than 200 faculty across multiple UConn campuses and at other regional academic and industry research institutions. This position will be a full-time appointment and will provide a unique opportunity to work in a rapidly growing and highly productive core facility at a large research university currently ranked in the top 25 of all public universities in the U.S.
MINIMUM QUALIFICATIONS
Master's degree in chemistry, biochemistry, analytical chemistry, or related field with at least 3 years of experience, OR Ph.D. degree in a similarly relevant field, with demonstrated experience implementing high resolution mass spectrometry for the analysis of proteins and peptides, and familiarity with operation, maintaining, and troubleshooting high resolution mass spectrometer and nanoflow ultra-high performance liquid chromatography systems.
Publication history that demonstrates successful application of state-of-the-art mass spectrometry for label-free and/or label-based (e.g. Tandem Mass Tags, iTRAQ, SILAC) quantitative proteomics.
Demonstrated experience using common proteomics software platforms for peptide/protein identification and quantification such as Spectronaut, MaxQuant/Andromeda, Proteome Discoverer, Byonic, and/or Scaffold Q+S.
Demonstrated mastery of sample preparation techniques for downstream proteomics analysis such as in-gel/in-solution digestions, co-immunoprecipitations, and processing of whole cell lysates or tissue homogenates for bottom-up proteomics.
Demonstrated clear and effective communication skills while communicating with researchers of varied scientific backgrounds, specifically regarding analytical techniques and informatics methods.
Experience working in a highly collaborative environment that emphasizes comprehensive analysis and one-on-one consultations with researchers.
PREFERRED QUALIFICATIONS
Experience with extensive collaborative projects or experience in a core facility setting.
Experience using Bruker tims TOF instrumentation for low input proteomic analysis utilizing DDA-PASEF and DIA-PASEF acquisition methods.
Experience with untargeted metabolomics workflows, including sample preparation and analysis using TOF instrumentation and small molecule identification using Progenesis QI, XCMS, and/or other programs.
APPOINTMENT TERMS
This is a full-time, 12-month, non-tenure-track position with an anticipated start date in February 2026. Salary will be commensurate with qualifications and experience. Other rights, terms, and conditions of employment are contained in the collective bargaining agreement between the University of Connecticut and the American Association of University Professors UConn Chapter (AAUP).
The University offers a competitive salary, and outstanding benefits, including employee and dependent tuition waivers at UConn, and a highly desirable work environment. For additional information regarding benefits, please visit hr.uconn.edu and explore the sections under the Benefits & Leaves and Engagement & Learning headers.
TERMS AND CONDITIONS OF EMPLOYMENT
Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check.
TO APPLY
Please apply online at https://hr.uconn.edu/jobs, Faculty and Staff Positions, Search #499108 and submit the following application materials: resume, cover letter, and contact information for three (3) professional references.
Questions regarding this search should be addressed to Dr. Jeremy Balsbaugh, Director of COR²E and PMF (jeremy.balsbaugh@uconn.edu).
This job posting is scheduled to be removed at 11:55 p.m. Eastern time on January 14, 2026.
All employees are subject to adherence to the State Code of Ethics which may be found at http://www.ct.gov/ethics/site/default.asp.
All members of the University of Connecticut are expected to exhibit appreciation of, and contribute to, an inclusive, respectful, and diverse environment for the University community.
The University of Connecticut aspires to create a community built on collaboration and belonging and has actively sought to create an inclusive culture within the workforce. The success of the University is dependent on the willingness of our diverse employee and student populations to share their rich perspectives and backgrounds in a respectful manner. This makes it essential for each member of our community to feel secure and welcomed and to thoroughly understand and believe that their ideas are respected by all. We strongly respect each individual employee's unique experiences and perspectives and encourage all members of the community to do the same. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
The University of Connecticut is an AA/EEO Employer.
$74k-107k yearly est. 60d+ ago
Postdoctoral Scientist - Watson Lab
Howard Hughes Medical Institute 4.7
Senior principal scientist job in Worcester, MA
Primary Work Address: 373 Plantation Street, Worcester, MA, 01605Current HHMI Employees, click here to apply via your Workday account.
About the Watson Lab
The Watson Lab at UMass Chan Medical School leads pioneering research in cancer systems-genomics by constructing tumor-like genomes in the lab to investigate chromosomal aberrations such as amplifications and deletions, as well as structural variants. Leveraging the principles of forward genetics and
in vitro
evolution, the lab generates aneuploid mutants from normal diploid epithelial cells to understand the origins and functions of recurrent chromosomal alterations found in human cancers. The Watson lab utilizes cell type of origin models for various cancer types to understand the tissue-specify of chromosomal alteration patterns in cancer.
By comparing these engineered genomes with genomic and transcriptomic data from human tumors, the Watson Lab seeks to uncover the functional roles-including phenotypic effects-of frequent chromosomal abnormalities, such as gains of 1q and 8q, thereby advancing our understanding of tumor biology and potential therapeutic targets.
🔗 Learn more about our work: Watson Lab website
About the Role:
We are seeking highly motivated Postdoctoral Scientists to run independent projects within the Watson Lab. This position is especially well-suited for:
New Ph.D. graduates or those with two years or less of prior postdoc experience.
Researchers trained in cancer biology or genomics seeking continuity in their research.
Individuals from related fields looking to transition into cancer genomics.
Postdocs in the Watson lab will leverage existing functional genetics methodologies in mammalian systems while also contributing to technology development in genomics and cancer biology. The role combines project ownership with opportunities to:
Mentor technicians and graduate students.
Collaborate on ongoing projects (e.g., establishing cell lines, refining methods).
Pursue co-authorship, fellowships, and independent funding with guidance from Dr. Watson.
This is an opportunity to drive high-impact research at the intersection of cancer biology, genomics, and methods innovation.
What You'll Get:
Opportunities to present your work at seminars, conferences, and scientific meetings.
Direct support in writing and securing fellowships, building toward independent funding.
Strong publication potential through first-author papers and collaborative manuscripts.
A genomics “playground” environment, with access to cutting-edge equipment (in-house NextSeq2000, etc), resources, and mentorship to explore ambitious projects.
Active encouragement to creatively develop new ideas and approaches.
What You Will Do:
Design, execute, and publish independent postdoctoral projects in cancer genomics and functional genetics.
Apply and develop novel methods and technologies in genomics and cancer biology.
Conduct experiments in mammalian systems using tissue culture, sequencing approaches, and molecular biology tools.
Support ongoing projects, contributing to resource development, method optimization, and collaborative publications.
Provide light mentorship to technicians and graduate students.
Present findings internally and externally, increasing scientific visibility.
What You Bring:
A Ph.D. in Cancer Biology, Genetics, Molecular Biology, or a related field.
0-2 years of postdoctoral experience (preferred, not required) - this is a great opportunity for newly graduated PhDs.
Proven ability to independently design and carry out projects.
Strong skills in tissue culture and molecular biology (required).
Experience with DNA sequencing, RNA sequencing, or single-cell sequencing (preferred but not required).
Interest or experience in technology development in genomics and cancer biology.
Additional computational/data analysis experience (preferred but not required).
Soft Skills:
A collaborative, team-oriented approach.
Excellent communication skills for writing, mentoring, and presentations.
Strong organizational skills with the ability to balance independent research and collaborative contributions.
Physical Requirements
Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).
Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.
Please Note:
This job description sets forth the job's principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.
#LI-JH1
Compensation and Benefits
Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more.
Compensation Range
$70,000.00 (minimum) - $80,500.00 (midpoint) - $91,000.00 (maximum)
Pay Type:
Annual
HHMI's salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal consistency when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.
HHMI is an Equal Opportunity Employer
We use E-Verify to confirm the identity and employment eligibility of all new hires.
$70k-91k yearly Auto-Apply 60d+ ago
Associate Research Scientist
Mindlance 4.6
Senior principal scientist job in Wallingford, CT
Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at *************************
Job Description
Position Description: The successful candidate will provide quantitative bioanalytical support using LC-MS/MS for a variety of high throughput in vitro ADME profiling assays. In this hands-on role, the candidate will perform sample analyses by mass spectrometry, and will review, interpret and report results. Instruments and software from various vendors including Sciex (Analyst) and Thermo (Excalibur) will be used along with custom internal data processing software to acquire data and process results. The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary.
Position Requirements: BS or MS in chemistry, with specialization in analytical chemistry preferred, along with 1 to 5 years of relevant pharmaceutical experience is required. Training or experience in mass spectrometry and separation science, as well as hands-on experience in quantitative LC-MS/MS analysis are desired. Proficiency in general computer software, including vendor specific instrument control and analysis tools, is required. Strong interpersonal and communication skills, both oral and written, are required as is commitment to working as a team player within a multifunctional organization. A working knowledge of allied disciplines such as computer science, lab automation, drug metabolism, pharmacokinetics and synthetic chemistry is helpful.
Qualifications
The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary.
LC-MS/MS analysis
BS or MS in chemistry
Additional Information
Thanks & Regards
Riya
************
$72k-98k yearly est. 60d+ ago
Confections Formulation Scientist
Curaleaf 4.1
Senior principal scientist job in Webster, MA
Job Description
At Curaleaf, we're redefining the cannabis industry with a strong commitment to quality, expertise, and innovation. As a leading global cannabis provider, our brands-including Curaleaf, Select, and Grassroots-offer premium products and services in both medical and adult-use markets.
Join us at Curaleaf to be part of a high-growth, purpose-driven company that champions corporate social responsibility through our
Rooted in Good
initiative, supporting community outreach and positive change. Here, you'll have the opportunity to make a meaningful impact, drive innovation, and help shape the future of cannabis.
Job Title: Confections Formulation Scientist
Location: Lexington, KY or Webster, MA (Relocation may be provided for the right candidate)
Job Type: Full Time | Exempt
Travel: Up to 50-75% to support our confection production facilities across the country
Who You Are:
You're a product development scientist with experience in confections, gummies, or candy formulation. You understand how hydrocolloids, pectin/gelatin systems, sugars, and emulsions work together to create consistent flavor, texture, and stability - and you know how to translate bench-top trials into scalable production. You bring deep knowledge of ingredient functionality, emulsions, and hydrocolloids, paired with the technical skill to scale formulations from the lab bench to full production. Whether running shelf-life studies, managing formulation data, or collaborating with cross-functional partners, you approach each challenge with precision, organization, and a problem-solving mindset. Above all, you're excited to push boundaries in the growing cannabis edibles space while upholding the highest standards of quality, safety, and compliance.
What You'll Do:
As a Confections Formulation Scientist, you'll play a central role in developing and scaling innovative cannabis-infused products. You'll conduct formulation trials, lead product testing, and support commercialization to bring new concepts to market. Your work will span from sensory evaluations to regulatory compliance, ensuring each product is safe, consistent, and high-quality. On any given day, you might be:
Supporting the development, optimization, and scaling of cannabis-infused edibles through bench trials, pilot runs, and full-scale production
Conducting sensory testing, shelf-life studies, and technical evaluations of texture, flavor, and stability using industry tools like viscometers and texture analyzers
Maintaining SOPs, batch records, and technical documentation to streamline operations and support audits
Ensuring compliance with GMP, food safety, labeling, and cannabis regulations, including coordinating third-party lab testing and interpreting results
Managing formulation and ingredient data using MRP systems and formulation software for efficiency and accuracy
Sharing data-driven insights that influence innovation, continuous improvement, and collaboration across the team
What You'll Bring:
5-8 years of experience in confectionery formulation and/or food manufacturing
A bachelor's degree in Food Science, Chemistry, Food Chemistry, or a related field
Hands-on experience in confection formulation and scale-up, with knowledge of production equipment
Strong understanding of ingredient functionality, food chemistry, emulsions, and hydrocolloids to design stable formulations
Familiarity with GMPs, food safety, and regulatory requirements, with direct experience in sensory testing and shelf-life evaluations
Excellent communication and documentation skills, paired with attention to detail and strong organizational abilities
Proficiency with Microsoft Office and formulation software
Willingness to travel for trials, production support, and industry events
Even Better If:
You have experience in the cannabis or hemp industry
You're familiar with ERP/MRP systems for managing formulations and ingredient tracking
You bring experience applying data science or analytics to product development
You've supported R&D trials and helped scale products from concept to commercialization
Physical Requirements:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this Job, the employee is regularly required to stand, walk, sit, talk or hear, use hands to finger or feel, reach with hands and arms, and lift up to 25 lbs. The employee is occasionally required to climb and balance, stoop, kneel, crouch, or crawl and lift up to 50 lbs. This position requires close vision, distance vision, peripheral vision, depth perception and the ability to adjust focus.
Work Environment:
This position has allergen warnings, potential exposure to dust, pollen, and plant pathogens, requires exposure to cleaning solvents, such as high volumes of isopropyl alcohol, requires daily use of provided PPE, such as masks, hair nets, beard covers, respirators, boot covers, scrubs, non-slip shoes, and Tyvek suits as necessary, requires the ability to work in confined spaces, has exposure to loud noises, including but not limited to air compressors, packaging equipment, and alarms, has exposure to CO2 manufacturing procedures at OSHA approved CO2 levels and requires a high stress tolerance, adaptability, and flexibility. Ability to work in an ever-changing environment.
Curaleaf Pay Transparency$78,000-$87,000 USD
What We Offer:
Career Growth Opportunities
Competitive Pay and Benefits
Generous PTO and Parental Leave
401(K) Retirement Plan
Life/ Disability Insurance
Community Involvement
Referral Bonuses and Product Discounts
Benefits vary by state, role type, and eligibility.
Follow us on Social Media:
Instagram: @curaleaf.usa
Twitter: @Curaleaf_Inc
LinkedIn: Curaleaf LinkedIn
Curaleaf Holdings, Inc. (TSX: CURA) (OTCQX: CURLF) ("Curaleaf") is a leading international provider of consumer products in cannabis with a mission to enhance lives by cultivating, sharing, and celebrating the power of the plant. As a high-growth cannabis company known for quality, expertise and reliability, the Company, and its brands, including Curaleaf, Select, Grassroots, JAMS, Find and Zero Proof provide industry-leading service, product selection and accessibility across the medical and adult-use markets. Curaleaf International is the largest vertically integrated cannabis company in Europe with a unique supply and distribution network throughout the European market, bringing together pioneering science and research with cutting-edge cultivation, extraction, and production. Home | Curaleaf | Cannabis with Confidence
Our Vision: To be the world's leading cannabis company by consistently delivering superior products and services and driving the global acceptance of cannabis.
Our Values:
Lead and Inspire.
Commit to Win.
ONE Curaleaf.
Driven to Deliver Excellence.
Curaleaf is an equal opportunity employer. Curaleaf recruits, employs, trains, compensates, and promotes regardless of race, religion, color, national origin, gender identity, sexual orientation, physical ability, age, veteran status, and other protected status as required by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Individuals adversely impacted by the war on drugs are encouraged to apply.
Current Curaleaf employees should apply for open positions through our Internal Job Board, which can be accessed via the link on The Leaf.
$78k-87k yearly 18d ago
Associate Scientist
Jackson Laboratory 4.3
Senior principal scientist job in Farmington, CT
The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders.
The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab.
Key Responsibilities & Essential Functions
* Platform Leadership: Serve as the Xenium Platform Lead and Subject Matter Expert (SME), providing guidance and support to end-users and the broader scientific community.
* Project Management & Execution: Coordinate the full lifecycle of Xenium projects, including managing sample submission and receiving, providing service quotations, executing experiments, and ensuring final data quality control (QC).
* System Maintenance: Oversee instrument management, including maintaining the Xenium instrument, managing stock and inventory, and performing advanced troubleshooting of equipment and assays.
* Process Optimization & Development: Drive the continuous improvement of the platform by optimizing existing workflows and developing new spatial genomics capabilities and technologies.
* Scientific Awareness: Stay current with the newest developments in the spatial genomics field and effectively communicate technological updates to the team and research community.
* Meticulous Documentation: Maintain excellent documentation standards, including comprehensive lab notebooks, SOPs, error/work logs, metadata, and sample information.
* Stakeholder Communication: Ensure seamless communication with end-users, vendors, colleagues, and managers to coordinate and successfully complete all Xenium projects.
Knowledge, Skills, and Abilities
Required
* Education: Master's degree (M.S.) in Biology, Molecular Biology, or a related scientific field.
* Experience: 2-4 years of experience in a core facility or industry setting.
* Molecular & RNA Biology: Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays.
* Imaging-Based Spatial Genomics Expertise: Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seq FISH.
* Technical Breadth: Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seq FISH).
* Sample Handling: Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques.
* Documentation: Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN).
* Operational Skills: Proven project and lab management experience, including managing stock, inventory, and instrument uptime.
* Soft Skills: Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups.
Preferred
* Education: Ph.D. preferred
* Single-Cell Experience: Hands-on experience with single-cell technologies (e.g., 10x Chromium, smart-seq, split-and-pool methods).
* Biopharma Industry Experience: Preferred experience working in an industrial setting, such as the biotechnology or pharmaceutical sector, demonstrating familiarity with industry-standard workflows and requirements.
* Histology Expertise: Experience in histopathology.
* Development: Proven track record in technology development or assay optimization.
Pay Range: $69,711 - $90,624
#CA-NL6
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit ************
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
How much does a senior principal scientist earn in Longmeadow, MA?
The average senior principal scientist in Longmeadow, MA earns between $82,000 and $158,000 annually. This compares to the national average senior principal scientist range of $83,000 to $169,000.
Average senior principal scientist salary in Longmeadow, MA