Senior principal scientist jobs in Manchester, CT - 146 jobs

Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at ************************* Job DescriptionPrimary Responsibilities: Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. Perform general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. Perform quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. Operate, maintain, calibrate and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. Maintain quality control and calibration logs of all Flow Cytometers. Analyze, summarize and document experimental results. Perform data entry using laboratory information management system (LIMS) Write experimental SOPs. Update Biomarker Lead on the status, results and problems in method development and performance of the assays. Complete all NHCRU/Client required training. Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. Possess multi-tasking and organizational skills. Experience in ELISpot Assays and FlowJo software a plus. Qualifications: Minimum of either MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information All your information will be kept confidential according to EEO guidelines.

Established in 1991, Collabera has been a leader in IT staffing for over 22 years and is one of the largest diversity IT staffing firms in the industry. As a half a billion dollar IT company, with more than 9,000 professionals across 30+ offices, Collabera offers comprehensive, cost-effective IT staffing & IT Services. We provide services to Fortune 500 and mid-size companies to meet their talent needs with high quality IT resources through Staff Augmentation, Global Talent Management, Value Added Services through CLASS (Competency Leveraged Advanced Staffing & Solutions) Permanent Placement Services and Vendor Management Programs. Collabera recognizes true potential of human capital and provides people the right opportunities for growth and professional excellence. Job Description •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Performed general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Performed quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operated, maintained, calibrated and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintained quality control and calibration logs of all Flow Cytometers. •Analyzed, summarized and document experimental results. •Performed data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pfizer required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information To schedule interview or get any further information feel free to contact: Sagar Rathore ************ ******************************

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years. Job Description Employee Responsibilities: Preparation of prototype formulations (solutions, suspensions, tablets, capsules, powder blends, semi-solid dosage forms, sterile and non-sterile liquids) for exploratory studies in in-vitro and in-vivo models Development of oral, topical, and intravenous (sterile) dosage forms for feasibility studies and small-scale manufacturing operations Measurement of key active compound and formulation properties (such as solubility, tablet hardness, disintegration, pH, isotonicity, color, gelling tendency, etc.) Assessment of the chemical and physical stability of prototype formulations, as well as the performance of prototype formulations using in-vitro tests (non-sink dissolution, precipitation, etc.) Identify potential stability and performance issues with prototype formulations Development of protocols for preparation of formulations at preclinical and clinical study sites Qualifications The Ideal Candidate would possess: Experience with drug formulation and pre-formulation techniques, and an understanding of drug candidate properties Basic chemistry (wet or solid state) laboratory experience. Experience working with laboratory equipment, mechanically inclined. Ability to follow procedures reliably and consistently, Strong computer and organizational skills Adept in Microsoft office Excellent communication (oral and written) and attention to detail Ability to work independently and as part of a team, self-motivared, adaptable, and a positive attitude Ability to learn new techniques, keep accurate records, follow instructions, and comply with company policies Additional Information The position is full-time, Monday through Friday, 8 a.m. to 5 p.m., with overtime as needed. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply. Ability to work overtime as required. Tasks require repetitive motion and standing for long periods of time. May be required to respond to off-shift operational issues. Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays #LI-EB1 Authorization to work in the United States indefinitely without restriction or sponsorship Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Job Title: Scientist- Mass Spectrometry Pay: $46-51/hour Zip Code: 06770 Job Type: Contract A Scientist- Mass Spectrometry job in Naugatuck, CT is available through Belcan. This is a contract opportunity with one of our key chemical clients. Responsibilities; * Mass Spectrometry skills for characterization of complex systems * Mass Spectrometry - operation, execute general analysis as directed by Mass Spec head. * REACH: European Regulatory compliance essential to do business in EU via Mass Spec experiments, interpretations. * Administrative function including participation in Safety programs, performance culture, my HR, etc. * Competency with GCMS, GCMSMS, LCMSMS essential. Qualifications: * Required Education & Experience: Ph.D. or equivalent, 5+ years' experience or BS/MS + 10 years' experience. * Industrial Chemistry experience is a plus. Pharma experience * Strong written and oral communication skills including live presentation. * Advanced expertise in various types of Mass Spectrometry- Spectrometrist * Basic expertise in Lubricant chemistry is a plus. Belcan is an equal opportunity employer. Your application and candidacy will not be considered based on race, color, sex, religion, creed, sexual orientation, gender identity, national origin, disability, genetic information, pregnancy, veteran status or any other characteristic protected by federal, state or local laws.

Job Title: Confections Formulation Scientist Job Type: Full Time | Exempt Travel: Up to 50-75% to support our confection production facilities across the country Who You Are: You're a product development scientist with experience in confections, gummies, or candy formulation. You understand how hydrocolloids, pectin/gelatin systems, sugars, and emulsions work together to create consistent flavor, texture, and stability - and you know how to translate bench-top trials into scalable production. You bring deep knowledge of ingredient functionality, emulsions, and hydrocolloids, paired with the technical skill to scale formulations from the lab bench to full production. Whether running shelf-life studies, managing formulation data, or collaborating with cross-functional partners, you approach each challenge with precision, organization, and a problem-solving mindset. Above all, you're excited to push boundaries in the growing cannabis edibles space while upholding the highest standards of quality, safety, and compliance. What You'll Do: As a Confections Formulation Scientist, you'll play a central role in developing and scaling innovative cannabis-infused products. You'll conduct formulation trials, lead product testing, and support commercialization to bring new concepts to market. Your work will span from sensory evaluations to regulatory compliance, ensuring each product is safe, consistent, and high-quality. On any given day, you might be: * Supporting the development, optimization, and scaling of cannabis-infused edibles through bench trials, pilot runs, and full-scale production * Conducting sensory testing, shelf-life studies, and technical evaluations of texture, flavor, and stability using industry tools like viscometers and texture analyzers * Maintaining SOPs, batch records, and technical documentation to streamline operations and support audits * Ensuring compliance with GMP, food safety, labeling, and cannabis regulations, including coordinating third-party lab testing and interpreting results * Managing formulation and ingredient data using MRP systems and formulation software for efficiency and accuracy * Sharing data-driven insights that influence innovation, continuous improvement, and collaboration across the team What You'll Bring: * 5-8 years of experience in confectionery formulation and/or food manufacturing * A bachelor's degree in Food Science, Chemistry, Food Chemistry, or a related field * Hands-on experience in confection formulation and scale-up, with knowledge of production equipment * Strong understanding of ingredient functionality, food chemistry, emulsions, and hydrocolloids to design stable formulations * Familiarity with GMPs, food safety, and regulatory requirements, with direct experience in sensory testing and shelf-life evaluations * Excellent communication and documentation skills, paired with attention to detail and strong organizational abilities * Proficiency with Microsoft Office and formulation software * Willingness to travel for trials, production support, and industry events Even Better If: * You have experience in the cannabis or hemp industry * You're familiar with ERP/MRP systems for managing formulations and ingredient tracking * You bring experience applying data science or analytics to product development * You've supported R&D trials and helped scale products from concept to commercialization Physical Requirements: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this Job, the employee is regularly required to stand, walk, sit, talk or hear, use hands to finger or feel, reach with hands and arms, and lift up to 25 lbs. The employee is occasionally required to climb and balance, stoop, kneel, crouch, or crawl and lift up to 50 lbs. This position requires close vision, distance vision, peripheral vision, depth perception and the ability to adjust focus. Work Environment: This position has allergen warnings, potential exposure to dust, pollen, and plant pathogens, requires exposure to cleaning solvents, such as high volumes of isopropyl alcohol, requires daily use of provided PPE, such as masks, hair nets, beard covers, respirators, boot covers, scrubs, non-slip shoes, and Tyvek suits as necessary, requires the ability to work in confined spaces, has exposure to loud noises, including but not limited to air compressors, packaging equipment, and alarms, has exposure to CO2 manufacturing procedures at OSHA approved CO2 levels and requires a high stress tolerance, adaptability, and flexibility. Ability to work in an ever-changing environment.

SCA Pharmaceuticals is a dynamic rapidly growing company consisting of passionate individuals who believe in our mission of providing high quality medications that are critical in saving and sustaining human life. SCA Pharma is an FDA 503B outsourcing facility providing customized medications for hospitals and healthcare facilities across the United States. We do this through unyielding quality, safety and integrity, our commitment to accountability and ownership, teamwork and problem solving. Summary: The Formulation Scientist is responsible for developing and optimizing sterile injectable formulations for 503B compounding operations. This role focuses on formulation design, scale-up, and technical support to ensure stability, manufacturability, and compliance with FDA and cGMP requirements. Key responsibilities include conducting compatibility and stability studies, preparing technical documentation for 503B compliance, and collaborating with cross-functional teams to support product development and scale-up. The Formulation Scientist provides formulation expertise during investigations and regulatory inspections as needed and contributes to new product initiatives and lifecycle management. Requirements Essential functions: Lead the design and development of pharmaceutical formulations for sterile injectables in compliance with FDA and cGMP standards. Scale up lab formulations to commercial production, ensuring reproducibility and robust results. Support evaluation of technologies and processes to improve product performance. Conduct compatibility studies using stability testing and chromatographic techniques. Develop and optimize formulations to ensure stability and manufacturability. Evaluate and select appropriate pharmaceutical API and excipients based on functionality, compatibility, and regulatory status. Provide formulation support to troubleshoot manufacturing challenges. Prepare formulation development reports and technical documentation to support 503B compliance. Provide technical support during regulatory inspections as needed. Support investigations and provide formulation input for deviations and change controls. Collaborate with cross-functional teams to support product development and scale-up. Provide formulation input for new product development initiatives. Additional responsibilities as assigned. Required Qualifications & Experience: Master's degree in biology, chemistry, engineering, or related field-or equivalent experience 5+ years in pharmaceutical formulation development; experience in sterile compounding or aseptic manufacturing preferred Strong knowledge of formulation science and excipients for sterile injectables Experience with sterile and compounded dosage forms Working knowledge of cGMP compliant Quality Systems and FDA regulations including 21 CFR Part 503B, USP compounding standards (795, 797, 800), and 21 CFR Parts 210 and 211 Proficiency with Quality by Design (QbD) principles and Design of Experiments (DOE) methodologies Strong project management, leadership and problem-solving abilities Proven ability to communicate and collaborate across teams Proficient in MS Office and statistical software Desired Knowledge, Skills, and Abilities: Experience with regulatory documentation and technical writing for 503B compliance. Understanding of risk management principles and failure mode effects analysis (FMEA). Ability to communicate complex scientific concepts to diverse audiences. Must be well organized and detail-oriented with proven initiative and self-starter skills. SCA Pharma is an equal opportunity employer (Minorities/Females/Disabled/Veterans). We recruit, employ, train, compensate, and promote without regard to race, religion, creed, color, national origin, age, gender, sexual orientation, marital status, disability, veteran status, or any other basis protected by applicable federal, state or local law.

About Us Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics. Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes. Cloverleaf's approach to drugging tRNA modifying enzymes uses engineered “trojan horse” tRNAs to modulate translation in cancerous cells. The programmability, potency, and specificity of our tRNAs gives us the potential to dramatically improve cancer treatment. The Job We are seeking an experienced In Vivo Scientist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will include designing and executing in house animal experiments in mice, proposing, planning and coordinating toxicity, pharmacology and efficacy studies at CROs, performing cell culture experiments with lead candidate RNAs to predict in vivo outcomes, and providing in vivo pharmacology and physiology expertise to accelerate development of our tRNA therapeutics. About You Excited by the science. We are excited by how science can improve the world and are looking for people who are too. Flexible. We wear many different hats and are looking for people who are willing to do whatever it takes to pitch in and get the job done. Resilient. Working in an early-stage startup can be hard. Science is hard. We are looking for people who have a demonstrated track record of sticking with complex problems for the long haul. Cooperative. As a small team, communication and collaboration are key. We are looking for people who thrive working both independently and collaboratively. Qualifications: PhD in Cancer Biology, Molecular Biology, or related fields. Strong problem solving skills Demonstrated ability to independently plan and execute in-vivo studies, data analysis and interpretation. Experience with mouse models of disease (preferably oncology) Skilled in mammalian cell culture, passaging/seeding cells, etc. Nice to haves: Research experience in RNA biology and/or RNA modifications field. Experience with therapeutic development. Experience with design/development RNA therapeutics and lipid nanoparticles. Previous experience selecting and overseeing work at CROs. Benefits Competitive salary commensurate with experience and strong equity incentives. Medical, dental, and vision coverage. Brand new lab space in BioLabs New Haven in downtown New Haven, close to the Yale Shuttle, I-95/91 and Metro North. We will provide a stimulating, collegial, and fast-paced environment. If you are interested in joining our team, then we are excited to hear from you! Please submit resumes at cloverleafbio.com

Makro Scientific: Growing Pharmaceutical, Biotechnology and Medical Device companies always need TOP Talent. Since 1996, MakroScientific's proven staffing solutions have helped many Life Sciences companies succeed and visualize their goals by increasing innovation and decreasing costs while maintaining the complex service level expectations. Our global presence with offices in USA (NJ, PA, IL, CA) and offices in UK, Europe and Asia enables us to be a powerful contributor and connector of right Talent. Job Description The scientist will work closely with his/her supervisor to conduct routine in vitro drug metabolism studies designed to evaluate molecules as inhibitors of drug metabolizing enzyme. The individual will work in the Pharmacokinetics, Dynamics and Metabolism (PDM) department to support R&D portfolios. Perform standard chemical calculations to accurately prepare laboratory solutions and dilutions for screening. Conduct in vitro experiments with bio hazardous material both manually and with robotic systems. Quantification of samples by LC/MS and analyzing data using excel and/or Graph Pad Prism. Generate high quality data in a timely manner, reviewing and uploading data into databases. With support of his/her supervisor and colleagues, the candidate will work as a member of a team and be accountable for the critical appraisal of their results. Accurate record keeping and ability to follow precise steps in a protocol are required. Perform and maintain lab supply inventory and order as appropriate Qualifications BS in chemistry, biochemistry, biology or related field.Exp 3-6 years Additional Information Must possess effective verbal and written communication skills. Ability to perform and record data entry via computer systems while adhering to laboratory SOPs is mandatory. Previous knowledge of Universal Precautions, Blood Borne Pathogen training, Microsoft Office including Excel and Graph Pad Prism is preferable. Candidate must be able to quickly learn new in-house software for data management. The candidate will have solid training and knowledge in standard chemical calculations to accurately prepare laboratory solutions and calculate dilutions for screening, Experience in assay development and mechanisms of enzyme inhibition are preferred. Experience with automation of assays and LC-MS is also desired.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years. Job Description Analysis of powder samples for key physical properties (such as particle size distribution, bulk density, true density, powder flow, particle shape) Analysis of liquid samples for key physical properties (such as viscosity and surface tension) Using techniques such as optical microscopy, laser diffraction particle size analysis, electron microscopy, shear cell testing, compaction simulation, etc. Qualifications Bachelor's degree in chemistry or other science related degree concentration, or equivalent directly-related experience At least one year experience in particle and powder characterization Strong computer, scientific, and organizational skills Proficient in learning new techniques, developing and carrying out experimental plans, and performing multiple tasks simultaneously Experience in data handling and scientific/engineering computations Excellent communication (oral and written) and attention to detail Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude Ability to keep accurate records, follow instructions, and comply with company policies At least one year experience in particle and powder characterization Additional Information Position is full-time, Monday - Friday 8am to 5 pm Ability to work overtime as required. Tasks require repetitive motion and standing for long periods of time. May be required to respond to off-shift operational issues. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply. Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays #LI-EB1 Authorization to work in the United States indefinitely without restriction or sponsorship Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description Good knowledge of Ligand binding assays as platforms for resolving pharmacokinetic parameters and a strong understanding of method development processes, acceptance criteria and incurred sample reanalysis for regulated studies/compounds. Good knowledge of regulatory requirement governing drug safety evaluation. Good understanding of modern bioanalytical chemistry. Demonstrated excellent communication, organization and interpersonal skills. Must have BS/BA degree in biology or chemistry and a minimum of 3 years of bioanalytical experience. Experiences in LBAs is highly desirable. Working knowledge of regulatory requirements (i.e., GLPs) is also required. Proven track record in working in the ADME related roles is preferred. Qualifications Must have BS/BA degree in biology or chemistry and a minimum of 3 years of bioanalytical experience. Experiences in LBAs is highly desirable. Working knowledge of regulatory requirements (i.e., GLPs) is also required. Proven track record in working in the ADME related roles is preferred. Additional Information For more information, please contact Sneha Shrivastava ************

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders. The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab. Key Responsibilities & Essential Functions * Platform Leadership: Serve as the Xenium Platform Lead and Subject Matter Expert (SME), providing guidance and support to end-users and the broader scientific community. * Project Management & Execution: Coordinate the full lifecycle of Xenium projects, including managing sample submission and receiving, providing service quotations, executing experiments, and ensuring final data quality control (QC). * System Maintenance: Oversee instrument management, including maintaining the Xenium instrument, managing stock and inventory, and performing advanced troubleshooting of equipment and assays. * Process Optimization & Development: Drive the continuous improvement of the platform by optimizing existing workflows and developing new spatial genomics capabilities and technologies. * Scientific Awareness: Stay current with the newest developments in the spatial genomics field and effectively communicate technological updates to the team and research community. * Meticulous Documentation: Maintain excellent documentation standards, including comprehensive lab notebooks, SOPs, error/work logs, metadata, and sample information. * Stakeholder Communication: Ensure seamless communication with end-users, vendors, colleagues, and managers to coordinate and successfully complete all Xenium projects. Knowledge, Skills, and Abilities Required * Education: Master's degree (M.S.) in Biology, Molecular Biology, or a related scientific field. * Experience: 2-4 years of experience in a core facility or industry setting. * Molecular & RNA Biology: Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays. * Imaging-Based Spatial Genomics Expertise: Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seq FISH. * Technical Breadth: Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seq FISH). * Sample Handling: Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques. * Documentation: Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN). * Operational Skills: Proven project and lab management experience, including managing stock, inventory, and instrument uptime. * Soft Skills: Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups. Preferred * Education: Ph.D. preferred * Single-Cell Experience: Hands-on experience with single-cell technologies (e.g., 10x Chromium, smart-seq, split-and-pool methods). * Biopharma Industry Experience: Preferred experience working in an industrial setting, such as the biotechnology or pharmaceutical sector, demonstrating familiarity with industry-standard workflows and requirements. * Histology Expertise: Experience in histopathology. * Development: Proven track record in technology development or assay optimization. Pay Range: $69,711 - $90,624 #CA-NL6 About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit ************ EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Global Channel Management is a technology company that specializes in various types of recruiting and staff augmentation. Our account managers and recruiters have over a decade of experience in various verticals. GCM understands the challenges companies face when it comes to the skills and experience needed to fill the void of the day to day function. Organizations need to reduce training and labor costs but at same requiring the best "talent " for the job. Qualifications BSc required with 2 years wet lab chemistry experience preferred. Degree in Chemistry, Biochemistry, Molecular Biology. • Preferred coursework includes Organic Chemistry, Statistics, Analytical Chemistry, Physical Chemistry, Biological Chemistry, corresponding Lab courses. TECHNICAL SKILLS • Design of Experiments • Kinetic analysis • Method development • Method troubleshooting • Some NMR experience preferred • pH measurement • weighing • pipetting POSITION RESPONSIBILITIES • Carry out chemical modifications of biopolymers under supervision. Involves weighing, pipetting, and mixing reagents under controlled conditions. • Sample purification using dialysis and filtration. • Preparation of samples for NMR analysis • Documention in electronic lab book • NMR analysis under supervision. Involves straightforward data collection. • Processing of NMR data • Statistical analysis of data • Preparation of aqueous buffers with pH analysis • Other routine duties and responsibilities involved in lab work. Additional Information $39//hr 12 months

Job Description Associate Principal Scientist, Process Chemistry FLSA Status: Exempt Salary: $130,000-$160,000 Pharmaron is thrilled to invite you to join us as our newest Associate Principal Scientist at our Coventry, RI facility! If you're craving a role that offers challenges, growth, and meaningful impact, then this is the opportunity you've been waiting for. Job Overview: The Associate Principal Scientist is a subject matter expert within Process Chemistry and is responsible for solving highly complex chemical development problems for ground-breaking Active Pharmaceutical Ingredient (API) development projects: Responsibilities: Design and execute core experiments, interpret results, and plan additional experiments in a timely manner to solve assigned problems of high complexity. Demonstrate expertise in the core chemistry laboratory skills required to support development and / or scale up of chemical processes Actively participate in the development of new technologies or methodologies Effectively communicate, coordinate and collaborate with cross-functional project groups to ensure that scientific work is appropriately documented such that the broader collaborative inputs and efforts are combined to maximum effect in the production of reports, manuscripts, and presentations. Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable, which may include significant contributions to manufacture of API for GLP toxicology studies or for GMP manufacture of clinical supplies. Contribute to effective team planning and mentor less experienced staff on core functional technical and procedural matters as opportunities arise. Follow all key internal business practices and external regulations governing the role (e.g. GLP or GMP), and adhere to all corporate policies governing the business activities. What We're Looking For: PhD in Chemistry or related field. Multi-year industrial experience within relevant role Evidence of experience in successful application of analytical / physical skill sets to resolve high complexity chemical problems Evidence of ability to effectively contribute to multi-disciplinary scientific teams Competency in the routine use of core instrumentation and laboratory techniques and higher end instrumentation and laboratory techniques. Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues Ability to work cross-functionally and manage projects effectively Excellent organizational, planning and time management skills Why Pharmaron? Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Primary Responsibilities: Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. Perform general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. Perform quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. Operate, maintain, calibrate and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. Maintain quality control and calibration logs of all Flow Cytometers. Analyze, summarize and document experimental results. Perform data entry using laboratory information management system (LIMS) Write experimental SOPs. Update Biomarker Lead on the status, results and problems in method development and performance of the assays. Complete all NHCRU/Client required training. Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. Possess multi-tasking and organizational skills. Experience in ELISpot Assays and FlowJo software a plus. Qualifications: Minimum of either MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information All your information will be kept confidential according to EEO guidelines.

Established in 1991, Collabera has been a leader in IT staffing for over 22 years and is one of the largest diversity IT staffing firms in the industry. As a half a billion dollar IT company, with more than 9,000 professionals across 30+ offices, Collabera offers comprehensive, cost-effective IT staffing & IT Services. We provide services to Fortune 500 and mid-size companies to meet their talent needs with high quality IT resources through Staff Augmentation, Global Talent Management, Value Added Services through CLASS (Competency Leveraged Advanced Staffing & Solutions) Permanent Placement Services and Vendor Management Programs. Collabera recognizes true potential of human capital and provides people the right opportunities for growth and professional excellence. Job Description •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Performed general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Performed quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operated, maintained, calibrated and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintained quality control and calibration logs of all Flow Cytometers. •Analyzed, summarized and document experimental results. •Performed data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pfizer required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information To schedule interview or get any further information feel free to contact: Sagar Rathore ************ ******************************

About Us Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics. Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes. Cloverleaf's approach to drugging tRNA modifying enzymes uses engineered “trojan horse” tRNAs to modulate translation in cancerous cells. The programmability, potency, and specificity of our tRNAs gives us the potential to dramatically improve cancer treatment. The Job We are seeking an experienced RNA Biochemist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will range from designing and performing both low and high-throughput RNA screening assays, generation of RNA sequencing libraries, performing mechanistic studies in cells on lead candidate RNAs, and diving into new disease areas beyond oncology. About You Excited by the science. We are excited by how science can improve the world and are looking for people who are too. Flexible. We wear many different hats and are looking for people who are willing to do whatever it takes to pitch in and get the job done. Resilient. Working in an early-stage startup can be hard. Science is hard. We are looking for people who have a demonstrated track record of sticking with complex problems for the long haul. Cooperative. As a small team, communication and collaboration are key. We are looking for people who thrive working both independently and collaboratively. Qualifications: PhD in Biochemistry, Molecular Biology, Genetics or related fields. Strong problem solving skills. Demonstrated ability to independently drive research projects to completion in academic or industrial settings. Experience with standard molecular biology techniques, including but not limited to, RNA/DNA extraction, PCR, RT-PCR, qPCR, western blotting, etc. Skilled in mammalian cell culture, passaging/seeding cells, etc. Nice to haves: Competency generating libraries for RNA sequencing (such as mRNA-seq, CLIP-seq, etc.). Comfortable at analyzing NGS data analysis using conventional bioinformatics tools. Research experience in tRNA, RNA biology and/or RNA modifications field. Experience with design/development RNA therapeutics and lipid nanoparticles. Experience with mouse models of oncology. Benefits Competitive salary commensurate with experience and strong equity incentives. Medical, dental, and vision coverage. Brand new lab space in BioLabs New Haven in downtown New Haven, close to the Yale Shuttle, I-95/91 and Metro North. We will provide a stimulating, collegial, and fast-paced environment. If you are interested in joining our team, then we are excited to hear from you! Please submit resumes at cloverleafbio.com

Makro Scientific: Growing Pharmaceutical, Biotechnology and Medical Device companies always need TOP Talent. Since 1996, MakroScientific's proven staffing solutions have helped many Life Sciences companies succeed and visualize their goals by increasing innovation and decreasing costs while maintaining the complex service level expectations. Our global presence with offices in USA (NJ, PA, IL, CA) and offices in UK, Europe and Asia enables us to be a powerful contributor and connector of right Talent. Job Description The scientist will work closely with his/her supervisor to conduct routine in vitro drug metabolism studies designed to evaluate molecules as inhibitors of drug metabolizing enzyme. The individual will work in the Pharmacokinetics, Dynamics and Metabolism (PDM) department to support R&D portfolios.Perform standard chemical calculations to accurately prepare laboratory solutions and dilutions for screening.Conduct in vitro experiments with bio hazardous material both manually and with robotic systems. Quantification of samples by LC/MS and analyzing data using excel and/or Graph Pad Prism.Generate high quality data in a timely manner, reviewing and uploading data into databases.With support of his/her supervisor and colleagues, the candidate will work as a member of a team and be accountable for the critical appraisal of their results.Accurate record keeping and ability to follow precise steps in a protocol are required.Perform and maintain lab supply inventory and order as appropriate Qualifications BS in chemistry, biochemistry, biology or related field.Exp 3-6 years Additional Information Must possess effective verbal and written communication skills.Ability to perform and record data entry via computer systems while adhering to laboratory SOPs is mandatory.Previous knowledge of Universal Precautions, Blood Borne Pathogen training, Microsoft Office including Excel and Graph Pad Prism is preferable.Candidate must be able to quickly learn new in-house software for data management.The candidate will have solid training and knowledge in standard chemical calculations to accurately prepare laboratory solutions and calculate dilutions for screening, Experience in assay development and mechanisms of enzyme inhibition are preferred.Experience with automation of assays and LC-MS is also desired.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description BS with 5+ year, MS with 2+ years experienced scientist to run flow cytometry clinical samples in a GCLP environment. In addition to running clinical samples, will also be involved for biomarker assay development and mechanistic studies. Ability to work occasional weekends for clinical sample analysis is required. Previous pharma and/or biotech experience preferred. Please list out the (up to) top three critical skills: 1. Cell-based and/or biomarker assay development 2, Flow cytometry 3. Cellular immunology Additional Information Best Regards, Anuj Mehta ************

Global Channel Management is a technology company that specializes in various types of recruiting and staff augmentation. Our account managers and recruiters have over a decade of experience in various verticals. GCM understands the challenges companies face when it comes to the skills and experience needed to fill the void of the day to day function. Organizations need to reduce training and labor costs but at same requiring the best "talent " for the job. Qualifications BSc required with 2 years wet lab chemistry experience preferred. Degree in Chemistry, Biochemistry, Molecular Biology. • Preferred coursework includes Organic Chemistry, Statistics, Analytical Chemistry, Physical Chemistry, Biological Chemistry, corresponding Lab courses. TECHNICAL SKILLS • Design of Experiments • Kinetic analysis • Method development • Method troubleshooting • Some NMR experience preferred • pH measurement • weighing • pipetting POSITION RESPONSIBILITIES • Carry out chemical modifications of biopolymers under supervision. Involves weighing, pipetting, and mixing reagents under controlled conditions. • Sample purification using dialysis and filtration. • Preparation of samples for NMR analysis • Documention in electronic lab book • NMR analysis under supervision. Involves straightforward data collection. • Processing of NMR data • Statistical analysis of data • Preparation of aqueous buffers with pH analysis • Other routine duties and responsibilities involved in lab work. Additional Information $39//hr 12 months