Scientist II
Senior principal scientist job in Oakland, CA
Pay Rate Range: $50.00/hr. - $55.24/hr.
Target Pay Rate: $55.24/hr.
Duration: 3 Months
Onsite
Shift (if applicable): M-F 8:00 AM - 5:00 PM
JOB DESCRIPTION
SUMMARY/JOB PURPOSE:
The Scientist II will be joining the Biotherapeutics Translational Pharmacology team to support our research programs. This position is primarily responsible for developing, optimizing and reporting out data for Bioanalytical assays for Antibody Drug Conjugates (ADC) to include ELISA, LC-MS and hybrid LC-MS techniques. This job will require the candidate to have excellent organization, communication, and teamwork skills, as well as flexibility and versatility, to meet tight deadlines in a dynamic, fast-moving environment.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
* Responsible for running analytical samples from nonclinical PK studies using ELISA, LC-MS and hybrid LC-MS techniques
* Operation and troubleshooting of automated instrumentation
* Collaborates with Biotherapeutics team members to support project advancement.
* Maintains electronic laboratory notebook in a complete, consistent, and timely manner in accordance with company intellectual property policies and practices.
* Prepares and organizes data for presentation. May present data and status reports at individual, group, and departmental research meetings under general supervision.
* Adherence to excellent health and safety practices and compliance with applicable EH&S safety rules and participates in mandatory safety training programs.
* Other responsibilities as assigned
SUPERVISORY RESPONSIBILITIES:
* No supervisory responsibilities
EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:
Education:
* Bachelor's degree in related discipline and a minimum of four years of related experience; or
* Master's degree in related discipline and a minimum of two years of related experience; or,
* Equivalent combination of education and experience.
Experience:
* Drug discovery experience is necessary with hands-on bioanalytical assay development with an excellent understanding of fundamental processes.
* Experience with ELISA, LC-MS and Hybrid LC-MS is required
* Experience using WinNonlin and PRISM applications are preferred.
Knowledge/Skills:
* Highly self-motivated with exceptional attention to detail is required.
* Thorough knowledge of activities related to bioanalytical assay development and data generation
* Excellent verbal and written communication skills with the ability to follow written instructions and SOPs.
* Ability to multi-task and excellent time management skills.
* Excellent work ethic, working effectively in both a team environment and independently.
* Thorough proficiency in MS Word, MS PowerPoint and MS Excel is required.
WORKING CONDITIONS:
* Primarily working in laboratory and office environment.
* Potential handling of hazardous materials, and brief periods of working in both 4°C and -20°C environments.
* May be required to work weekends as needed.
All qualified applicants will receive consideration for employment without regard to race, color, national origin, age, ancestry, religion, sex, sexual orientation, gender identity, gender expression, marital status, disability, medical condition, genetic information, pregnancy, or military or veteran status. We consider all qualified applicants, including those with criminal histories, in a manner consistent with state and local laws, including the California Fair Chance Act, City of Los Angeles' Fair Chance Initiative for Hiring Ordinance, and Los Angeles County Fair Chance Ordinance. For unincorporated Los Angeles county, to the extent our customers require a background check for certain positions, the Company faces a significant risk to its business operations and business reputation unless a review of criminal history is conducted for those specific job positions.
Research Scientist
Senior principal scientist job in Santa Rosa, CA
About the Company
We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks.
About the Role
As a Research Scientist, you will develop new benchmarks, methodologies, and evaluation pipelines that shape how cutting-edge models are assessed, compared, and deployed in production environments. Your work will directly influence model selection and safety decisions across foundation model labs, high-growth AI product companies, and Fortune-scale enterprises.
Responsibilities
Benchmarking & Model Analysis
Evaluate newly released models as they launch (e.g., Gemini, DeepSeek, etc.)
Run large-scale assessment workflows using internal evaluation infrastructure
Compare model performance across enterprise-grade task categories
Design New Benchmarks from Scratch
Identify high-value model application domains through research exploration
Construct datasets, including labeling strategy and workforce coordination
Write short “white-paper-style” summaries explaining benchmark purpose, method, and findings
Advance Automated Evaluation Methodologies
Improve systems for scoring generated text beyond standard metrics
Explore research in reference-free, rubric-based, and human-aligned evaluation
Develop new techniques for reliability, consistency, and repeatability
Cross-functional Collaboration
Work closely with engineering to scale evaluation infra
Partner with customers to refine evaluation relevance and task fit
Influence product direction through research insights
Qualifications
0-3 years post-grad experience (Master's, PhD, or equivalent applied research)
Publications, preprints, or demos showing cutting-edge work
Experience with diffusion models, NLP, multimodal, or benchmarking work
Ability to operate independently with ambiguity
Clean, maintainable research codebases
Candidates from:
top engineering/research universities
applied AI startups
well-regarded research internships
Required Skills
Built or contributed to a benchmark or evaluation methodology
Experience in enterprise task model evaluation
Stanford / top lab adjacency (per their historical hiring success)
Preferred Skills
Wants to publish as primary motivation
Purely academic with slow timelines
Big-tech culture fit concerns (Meta / Google / Salesforce specifically noted-but case-by-case)
Pay range and compensation package
Base Salary: up to $250K depending on background
Equity: typically 0.3% - 0.5%, flexibility for exceptional candidates
Rapid equity refresh possible based on impact
Equal Opportunity Statement
Visa sponsorship available. Relocation support. Health & dental coverage. Lunch + dinner provided, snacks & coffee. Unlimited PTO. Weekly happy hours with community guests. Team events (bowling, hiking, rock climbing, etc.). Swag program (hats, etc.).
Work Environment & Culture
In-person, San Francisco HQ (required). Core hours: 9-5, some teammates extend voluntarily. Most team members work 1 weekend day per week (flexible). High-ownership, low-ego, collaborative. Live demos Mondays, team lunch Thursdays, community Fridays. Early-stage pace, applied focus-not academic publishing.
Tech Environment
(while research-focused, exposure beneficial) Backend: Python / Django. Frontend: React + TypeScript. Infra: AWS. Evaluation frameworks + internal tooling.
Why This Role Is Unique
The company already collaborates with foundation model labs, high-growth AI vertical product companies, and Fortune 500 enterprises (not publicly facing). ChatGPT Vals AI $5M seed raised, runway of 2+ years at current burn. Only one research scientist is being hired-true founding impact. Opportunity to define industry standards for model trust, reliability, and certification. Positioned to become the rating agency for generative AI.
Research Scientist
Senior principal scientist job in Santa Rosa, CA
Applied Scientist
Package - > $200 - 250k Cash + Benefits
A scaling, SOTA Generative AI Startup operating with a world class team (Founders have multiple prior exits) with talent from Open AI, IBM, MIT and several top orgs, focused on pioneering work and advancements in large language models (LLMs), code generation, and code translation. Their projects directly involve industry leading partners where they're applying advanced AI to solve meaningful, practical challenges with real-world impact.
Broad Responsibilities:
Design, execute, and analyze experiments with a high degree of independence
Contribute to core models and frameworks
Create high-quality datasets (both in-the-wild and synthetic)
Perform literature reviews and implement new techniques from papers
Contribute to publications, present at conferences and workshops, etc.
Requirements:
Ph.D. in Computer Science or another STEM subject
Prior LLM research experience
Comfortable programming in Python and familiar with frameworks such as PyTorch and HuggingFace
Preferred Qualifications:
Publications at peer-reviewed conferences such as NeurIPS, ICLR, ICML, etc.
Experience with large-scale LLM training, particularly in a distributed computing environment
Get in touch today for more details and immediate consideration / interview!
Research Scientist
Senior principal scientist job in Santa Rosa, CA
We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring a Research Scientist on a hybrid basis.
They have seen $300M in a recent fund raise.
Skills targeted:
PhD in Physics/ Quantum Physics/ Theory/ Statistics/ Mathematics/ Computational Science or similarly related field.
2+ YoE working with AI Agents.
Good exposure to LLMs.
TC package of $1-1,5M with sizeable base salary & equity package.
If that looks of interest, apply & Goliath will be in touch!
Research Scientist - Vision Data Infrastructure
Senior principal scientist job in San Francisco, CA
⚡ Research Scientists/Engineers (all levels)
🔍 Focus on Vision Data Infrastructure
🤖 Fundamental AI Research Institute
🌎 San Francisco Bay Area, USA
💸 $250,000 - $600,000 salary + annual bonus
Come join one of the only research institutions globally with resources to compete with top AI companies =>10s of 1000s of GPUs to explore state-of-the-art research in LLMs, Multimodal and Agentic AI.
Currently seeking AI talent with expertise in building scalable pipelines for vision data to support both image/video generative training and multi-modal alignment. You'll design high-performance pipelines for large-scale image and video datasets, enabling efficient pretraining, alignment, and simulation-based data generation.
Responsibilities:
Vision Data Sourcing & Curation
Collect and organize image and video data from open datasets and the web.
Handle data cleaning, filtering, deduplication, and metadata generation.
Ensure ethical and compliant data collection at scale.
Processing & Augmentation
Build high-throughput pipelines for vision data preprocessing (frame extraction, resolution normalization, format conversion, latent caching).
Implement GPU-accelerated augmentation and distributed data loading (WebDataset, TFRecords, Parquet).
Synthetic & Simulation-Based Data Generation
Use simulation tools (e.g., Unreal Engine 5, Isaac Sim, Unity) to generate high-quality synthetic vision data.
Create specialized datasets for VLM training, visual reasoning, and agent interaction.
Requirements:
Strong experience with data engineering, computer vision, or machine learning infrastructure.
Expertise in building and scaling ETL/data pipelines for large unstructured datasets.
Proficiency with Python, PyTorch, and distributed data frameworks (e.g., Ray, Spark, Dask).
Experience with WebDataset, TFRecords, Parquet, or similar high-throughput data formats.
Familiarity with GPU-accelerated preprocessing, NVIDIA DALI, or equivalent systems.
Understanding of image/video codecs, data compression, and cloud storage optimization.
Preferred Experience:
Prior work with simulation-based or synthetic data generation using Unreal Engine, Isaac Sim, or Unity.
Experience curating datasets for multimodal or vision-language model training.
Knowledge of data ethics, privacy, and compliance frameworks for large-scale AI datasets.
Experience contributing to open datasets or data-centric AI research.
Why apply:
Opportunity to join a fast-growing core team that are already pushing AI breakthroughs
Highly competitive salary package
Work alongside ambitious and bright superstars from tech and academia
Medical, Dental and Vision Insurance
Relocation package available
🌎 San Francisco Bay Area, USA
📧 Interested in applying? Please click on the ‘Easy Apply' button or alternatively email me your resume at
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Scientist/Sr. Scientist-Stem Cell Biology/Embryology
Senior principal scientist job in Santa Rosa, CA
located in San Francisco, CA
Responsibilities of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology:
Design and execute experiments in stem cell differentiation, organoid generation, and tissue engineering.
Innovate then execute experiments to generate and differentiate human stem cells, develop functional assays, assess and interpret experimental workflows
Perform mammalian embryo dissections, tissue isolations, and culture experiments to study and model developmental processes.
Apply principles of developmental biology and embryology to guide tissue maturation and patterning.
Collaborate with biomaterials and engineering teams to integrate cells and tissues.
Develop and optimize protocols for reproducible tissue generation and maintenance.
Test novel stem cell culture conditions, sort, screen, expand and differentiate hi PSCs according to latest protocols and newly developed approaches.
Requirements of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology:
PhD in biological sciences, stem cell biology, genetics or related field.
2+ years hands-on expertise in stem cell culture (iPSCs/ESCs).
Hands-on experience with mammalian embryos, including dissections and culture.
Experience in molecular biology and strong problem solving skills.
Senior Research Scientist, Biophysics
Senior principal scientist job in South San Francisco, CA
Yoh is looking for a skilled and driven Senior Research Scientist, Biophysics with hands-on experience in small molecule drug discovery to join our collaborative Lead Discovery team. This is a lab-based role focused on the biophysical and mechanistic characterization of small molecule-protein interactions to support our drug discovery pipeline. This candidate must have hands on experience with designing and executing binding characterization studies using SPR.
Industry: Discovery and Development
Location: South San Francisco, CA
Key Responsibilities:
Design and execute binding characterization studies using SPR (Biacore S200 and 8K+).
Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nano DSF, DLS, Spectral Shift).
Manage and coordinate outsourced biophysical studies with CROs.
Analyze and interpret data to support SAR and lead optimization across multiple projects.
Maintain detailed experimental records and present findings in internal meetings and reports.
Qualifications:
PhD in Biophysics, Biochemistry, or a related field.
Minimum 3 years of relevant industry experience in small molecule drug discovery biophysics.
Proven expertise in SPR assay development and data interpretation.
Demonstrated expertise in designing, developing, and interpreting biophysical characterization of small molecule-protein interactions by SPR.
Strong familiarity with additional biophysical techniques (TSA, DLS, Spectral Shift, NMR, ITC, etc.).
Proficiency with data analysis and graphing tools is a plus.
#IND-SPG
Estimated Min Rate: $70.00
Estimated Max Rate: $80.00
What's In It for You?
We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh's network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh's extensive talent community that will provide you with access to Yoh's vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:
Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
Health Savings Account (HSA) (for employees working 20+ hours per week)
Life & Disability Insurance (for employees working 20+ hours per week)
MetLife Voluntary Benefits
Employee Assistance Program (EAP)
401K Retirement Savings Plan
Direct Deposit & weekly epayroll
Referral Bonus Programs
Certification and training opportunities
Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Visit ************************************************ to contact us if you are an individual with a disability and require accommodation in the application process.
For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh's hiring clients' preferences. To learn more about Yoh's privacy practices, please see our Candidate Privacy Notice: **********************************
Product Development Scientist
Senior principal scientist job in San Francisco, CA
We are a group of people united by a strong purpose.
We want you to get to know us, and Giuseppe, our very own artificial intelligence.
We love good food, but above all, we love the planet, and that's why, to protect it, we reinvent the food industry, one delicious bite at a time, elevating what we eat, through our technology and based on plants.
Our recipe has three mega-important components: science, technology, and of course, disruptive talents who work daily to create a better future.
At NotCo we are not and do not seek to be the perfect company, but rather the right one. We are here to produce changes, and that is why we dare, fail, and sometimes achieve incredible successes.
We are currently looking for a Product Development Scientist for our NotCo B2B Research & Development located in San Francisco, California, requiring an active on-site presence. This position will report to our R&D Sr. Team Lead and the incumbent will work cross-functionally to ensure R&D activities are successfully deployed locally.
Responsible for the:
Independently conducts day-to-day product development activities as directed by the manager across multiple projects. This includes supporting activities related to the full product lifecycle process (from product concept to successful commercial launch as needed)and supporting process development, scale-up and technology transfer
Supports the design and execution of bench-top tests, pilot-plant trials and full-scale formulations to deliver high-quality food products that meet and exceed the sensory, cost, and other performance targets
Proactively proposes and uses sensory and analytical analysis to guide and validate the development process
Maintains detailed documentation, experiment tracking and outcomes, and documents finished goods and ingredient specifications
Provides feedback to project lead regarding relevant technical and process information
Communicates proactively and effectively with cross-functional teams, clearly articulating perspectives and trade-offs related to new product development goals
Utilizes NotCo's proprietary AI technology to develop and improve food products
Supports formula validation activities as well as process development, scale-up and technology transfer
Engages in client communications and workshops, bringing technical
Maintains detailed documentation across all R&D activities in a timely manner
Qualifications / Requirements:
Bachelor's degree in Food Engineering, Food Science, Engineering in Biotechnology or a similar discipline.
2 + years of Food R&D experience is desired, preferably across both food and beverage categories.
Be agile, adaptable, and thrive in a dynamic and changing culture; works relentlessly to overachieve, anticipate obstacles, and create plans to overcome them.
Adapts easily to changing priorities and direction based on new project learnings and team priorities.
Demonstrated competency to effectively communicate (oral & written) cross-functionally with solid collaboration skills.
Comfortable in client-facing situations and able to communicate complex topics clearly and simply.
Excel in a startup environment, is excited to create new procedures and processes from scratch and has a strong entrepreneurial mindset.
Be a problem solver, have a general manager mindset, and take the initiative to get the job done
Possess strong planning, project management, and execution skills, and the ability to articulate where and how you have used them.
Rigorous data-driven/analytical capability and ability and presence to present data effectively to a leadership team
Work well in teams and cross-functional groups in a matrixed environment, both regionally and globally
Possesses strong computer skills, including a high level of proficiency in MS Office, specifically Excel
Authorization to work in the U.S. is required
Ability to travel up to 50% of the time, including international travel and extended trips.
NotCo is committed to fair and equitable compensation practices. The pay range for this role is $65,000 - $75,000. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor.
We are an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
Sr Scientist/ Associate Principal Scientist, LCMS Platforms
Senior principal scientist job in Pleasanton, CA
Job DescriptionBenefits:
401(k)
401(k) matching
Bonus based on performance
Dental insurance
Free food & snacks
Health insurance
Paid time off
Parental leave
Vision insurance
Position Summary:
Crystal Bio Solutions is a CRO providing global-standard services in GLP/GCLP bioanalysis and biomarker. Our clients include multinational pharmaceutical companies and biotech companies.
The Bioanalysis & Biomarkers Department specializes in Method Development, Method Validation, GLP/GCLP Bioanalysis for PK, and biomarkers. The team has successfully supported non-GLP, GLP (non-clinical) and GCLP (clinical) projects. The role is responsible for providing bioanalytical support for both pre-clinical and clinical projects and partnering with our clients for project success.
Key Responsibilities:
Independently propose assay design and/or strategy, develop, validate, conduct, and troubleshoot LCMS-based bioanalytical methods for the quantification of small molecule (and its metabolites) and biologics (e.g. ADC, mAB, protein, peptide, oligonucleotide etc) in support of PK, and Biomarker measurement
Conduct or oversee GLP/GCLP sample analysis and data reporting.
Present and interpret data internally and/or externally as needed.
Serve as the Principal Investigator responsible for interaction with the client from the study design to scheduling, conducting, reporting, and transferring data. Ensure responsiveness to the client, timely delivery, and overall customer satisfaction.
Serve as Subject Matter Expert (SME) for LCMS platform
Ensure GLP/GCLP compliance, including accurate documentation and adherence to established procedures
Author and/or review key regulatory documents, validation plans and reports, laboratory data, and technical reports.
Provide technical leadership for LC-MS as a Subject Matter Expert, and mentor junior scientists.
Assist in improving policies, procedures, work instructions and SOPs
Understand and adhere to corporate standards regarding code of conduct, Environment Health & Safety (EHS), and GLP/GCP/GDP compliance.
Perform other related duties as assigned
Qualifications & Educational Requirements:
Ph.D., M.Sc., M.A., B.A., in Biology, Immunology, Chemistry, Pharmacology, or other related scientific fields required, including a minimum of 4+(Ph.D.), 9+(Masters) or 12+(Bachelors) years of CRO/Pharma/Biotech experience.
Hands-on experience and strong knowledge of GLP/GCLP bioanalysis.
Experienced with GLP/GCLP LCMS method development and validation for PK and/or biomarker analysis.
Functional experience utilizing LIMS and QMS systems for GLP/GCLP bioanalysis
Established record of independent achievement of objectives and timelines while maintaining high work quality.
Effective in team environments co-workers, managers, and clients
Must be goal-oriented, compliance-ensured, quality-conscientious, and client-focused.
Effective writing and communication skills are required.
Experience in large molecule LCMS analysis (e.g. ADC, mAB, protein, peptide, oligonucleotide etc) preferred.
Familiarity with additional bioanalytical platforms (e.g. LBA, PCR, Flow Cytometry) preferred.
Supervisory experience in both project and talent (people) management is preferred.
Pay Transparency Statement
Title and compensation will be based on experience ( Senior Scientist / Associate Principal Scientist).
At CP, your base pay is only part of your overall total compensation package. At the time of this posting, this role typically pays an annual base salary between $110,000 and $160,000 per year. The range displayed reflects the minimum and maximum target for new hires. Actual pay may be more or less than the posted range. Factors that influence pay include the individual's skills, qualifications, education, experience, and the position level and location.
Agency Notice Direct Applicants OnlyWe are currently handling this recruitment directly and are not engaging with external recruiters or staffing vendors for this position. Thank you for your understanding.
Sr Formulations Scientist III - Valent U.S.A LLC
Senior principal scientist job in San Ramon, CA
Job Description
About us:
Valent U.S.A. LLC, a wholly owned subsidiary of Sumitomo Chemical Company, Limited, engages in the development, registration, sales, and marketing of integrated technological solutions for crop production and pest management that deliver value for our customers and stakeholders. A leading crop protection firm serving the agricultural and non-crop products markets in North America, Valent products help growers produce safe and abundant food and fiber crops, and horticultural professionals improve the quality of life for their customers. The corporate motto, Products That Work, From People Who Care , describes the company's business philosophy. Valent seeks out and provides customers with innovative and effective solutions to their production challenges. Our vision is to be the best company delivering integrated solutions of biorational and traditional crop protection solutions to our customers. Valent is dedicated to creating a world that is healthier and more comfortable, and that has a sustainable abundance of quality, affordable food, helping crops to be the ultimate renewable resource.
General Description:
The purpose of this position is to conduct research and development efforts for Herbicide product development from conceptual phase through commercial production by working in coordination with the Senior Manager of Formulation Development and Analytical. The position is responsible to execute all related scientific research and/or development studies assigned for critical product development by individual effort or in collaboration with staff. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plan and executes lab research. Maintain broad knowledge of state-of-the-art principles and theories. Make major contributions to scientific literature and conferences. Serve as in-house and outside consultant. May act as spokesperson on corporate research and development and advise top management. Participate in development of patent applications. Participate in promoting the professional development of junior research staff. Interfaces with various associated departments. Uses professional concepts to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways.
Principal Responsibilities:
Use expert knowledge to independently plan, execute, and/or direct complex research and development projects for new or improved/innovative formulations and formulation technology, particularly in herbicide product segment. Manage formulation development activities through all stages of the project: development of preliminary formulations for efficacy testing, formulation optimization and processing studies to establish formulation for regulatory studies and EPA registration, scale-up, and commercial production. Exercise wide latitude in determining objectives and approaches, selecting methods, techniques and evaluation criteria for obtaining results. Requires coordination and communication with other Valent teams, including, Product Development Managers, Regulatory Project Managers, Toxicology Manager, Supply Chain, and production facility personnel. Provide technical support services to Manufacturing, Product Development Managers, Marketing, and Sales to solve technical problems or customer complaints related to Valent formulations.
Work directly and independently with Market/Product Managers, Technology Managers and Product Development specialists to investigate feasibility for exploratory projects and to set objectives and maintain timelines for development projects for new or improved/innovative formulations and formulation technology. Serve as a resource and source for ideas for product innovation. Interact with Sumitomo Group Companies' formulation chemists, consultants, and industry personnel regarding research, development, and alternative technologies for formulation improvements. Evaluate formulation technology advances for application to Valent products and lead implementation efforts across product line. Viewed as an expert in all aspects of formulation research and development.
Communicate proactively and effectively, both orally and in writing, with Senior Formulation Manager, Technology staff, personnel in other functional areas, and with appropriate external personnel, to ensure that projects are progressing on track and meet objectives and timelines: provide information on formulation project status and results; set priorities; resolve problems or issues; coordinate activities; and obtain feedback and needed information or assistance. Serve as consultant to management and as an external spokesperson for the company. Advise on direction for strategic planning from technical perspective to meet company objectives. May serve on industry committees or task forces.
Engage Associate/Formulations Scientists in conduct of tasks/projects; train and develop; communicate priorities and objectives when collaborating; review work from subordinates. Serve as a resource/trainer/mentor for junior members of the group. Follow safety and regulatory plans, and waste disposal procedures. Participate in all required safety meetings and training programs.
Perform research and/or development in collaboration with others for projects. Make detailed observations, analyze data and interpret results. Exercise technical discretion in the design, execution and interpretation of experiments that contribute to project strategies. Prepare technical reports, summaries, protocols, and quantitative analyses. Maintain familiarity with current scientific literature. Contribute to project process within his/her scientific discipline. Investigate, create and develop new methods and technologies for project advancement. Maintain high level of professional expertise through familiarity with scientific literature. May participate in scientific conferences and contribute to scientific journals. May be responsible for identifying patentable inventions. Use professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.
Manage all formulation development activities for assigned products. This includes constant interfacing with the other members of the Seed Treatment, Fungicide, Insecticide and Herbicide Teams in both Field Development and Marketing. Maintain expertise in all aspects of technology including requirements for various formulations, application methods, and test methods. Utilize knowledge and expertise to develop formulations that can be registered, commercialized, and meet customer needs and expectations. Serve as formulation technology expert in meetings with various companies, customers, and prospective or established business partners.
Qualifications:
MS, PhD, JD or equivalent, with 8+ years of related experience.
Chemistry, related science degree.
Experience in spreadsheets and word processing, problem solving, communication, detail oriented, evaluation and interpretation of data, instrument/equipment operation, maintenance and repair.
In-depth knowledge of chemistry lab procedures, formulation development, manufacturing and packaging of agricultural chemicals and EPA approved inerts. Techniques for preparation and evaluation of formulations.
More than 8 years of experience in preparation and evaluation of agricultural chemical formulations. More than 6 years experience in managing laboratory formulation research projects and technical support in the agricultural chemical industry.
Demonstrated creativity, championing skills and deep technical knowledge of herbicide formulations and performance/stability requirements.
Physical Demands and Work Environment (LAB Position)
The physical demands and work environment characteristics described below are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Physical Demands include constant sitting, walking, standing, bending at the neck and waist, squatting, climbing, kneeling, crawling, twisting at the neck and waist, simple grasping, power grasping, and fine manipulation with hands, pushing and pulling with hands, reaching above shoulder level, and lifting and carrying up to 25 lbs.; and occasional lifting and carrying of up to 50 lbs. Will require the employee to lift and carry up to a 2.5-gallon jug containing liquid formulations and products. May be required to work in powder room environment to test or develop dry formulation products. This includes milling activities for solid formulations (granular and powder) in a dusty environment that will require the use of respirator and other personal protective equipment.
Work Environment includes exposure to or working in or around moving cars, trucks, forklifts, equipment and machinery including a computer keyboard and mouse; uneven ground; excessive noise; extremes in temperature, humidity, or wetness; dust, gas, fumes, or chemicals; heights; operation of foot controls or repetitive foot movement. May be required to wear a respirator and other personnel protective equipment (including special visual or auditory equipment).
May require occasional travel.
Requires on-site laboratory base of operation.
Frequency Definitions: Constant = Over 40% / Frequent = Up to 40% / Occasional = Up to 10%
What We Offer
We recognize that compensation and benefits play a crucial role in your career decisions. That's why we're dedicated to equitable pay practices and transparency in how we reward our employees.
Base Salary: The estimated annual base salary for this position ranges from:
$95,400 to $123,600 . Individual pay is based upon location, skills, experience, and other relevant factors.
Incentives: All full-time employees are eligible for an incentive program or profit-sharing program in addition to their base salary.
Benefits:
High-quality healthcare coverage starting on day one, with options for medical (HSA/HRA), vision, and dental plans
5% company contribution to your 401(k), plus a quarterly discretionary bonus
Immediate 100% vesting of all retirement contributions
Financial assistance programs to support your goals
Life and disability insurance for added security
Generous paid time off, including vacation, holidays, and volunteer days
Our Commitment to a Sustainable Future
At Valent Group of Companies, we're proud to power a sustainable future through our work. Sustainability and corporate social responsibility (CSR) have been at the core of our culture since the beginning. Today, they continue to drive everything we do.
Join us in making a meaningful impact and contributing to a better world.
Valent U.S.A., Valent North America LLC, Valent BioSciences LLC and Mycorrhizal Applications LLC are an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation and/or identity, national origin, citizenship, immigration status, disabilities, or protected veteran status.
#LI-ONSITE
Scientist I/II, CRISPR-X
Senior principal scientist job in San Francisco, CA
Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. The Nobel Prize-winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially transformative medicines. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California, and business offices in London, United Kingdom.
Position Summary
Are you passionate about developing next-gen CRISPR therapies? We are seeking a highly motivated and creative Scientist to grow our diverse, innovation-focused CRISPR-X team that pioneers novel gene editing therapies for human disease. We are part of CRISPR Therapeutics, a leading gene editing company with a broad clinical portfolio, and research sites in Boston and San Francisco. The successful candidate will be an integral part of our team, whose aim is to research, develop and advance the next generation of genome editing modalities and genetic therapies for a wide range of human indications. The position requires enthusiasm, passion, outstanding skills in the art, attention to detail, and a desire to create new medicines for patients.
Responsibilities
Lead, design, and optimize research with the aims of exploring and developing next-generation gene editing strategies using CRISPR-based tools and beyond.
Design, execute, and interpret research requiring molecular biology techniques including cloning, qPCR/dd PCR, NGS, RNA and DNA analysis, cell culture, and other cell-based assays.
Analyze and present experimental data to a wide range of audiences.
Dissect published literature to find novel solutions to gene editing problems.
Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate.
Minimum Qualifications
Prior experience with gene editing, including applying and developing next generation gene editing technologies, such as prime editing, base editing, and recombinases and retrotransposons, in an academic and/or industry setting, with a track record demonstrating significant contributions.
Ph.D. in biology, bioengineering, or related discipline.
Scientist I - 0-3 years of professional experience
Scientist II - 2-5 years of professional experience
Outstanding problem-solving skills and attitude to think outside the box.
Expertise in molecular biology, cell culture techniques and hepatocytes.
Excellent writing, reviewing, and presentation skills.
Challenges oneself continuously to enhance scientific capabilities.
Ability to work independently as well as collaboratively in a results-oriented research team environment.
Must possess critical thinking and self-reliance to solve tasks independently.
Self-motivated and scientifically rigorous, with outstanding organization and multitasking capability
Entrepreneurial spirit showing resourcefulness, accountability, agility to pivot, transparency, and productivity.
Preferred Qualifications
Prior experience with protein and/or RNA engineering.
Prior experience with diverse delivery technologies, including transfection/nucleofection, lipid nanoparticles, and viral vectors/particles.
Prior experience with primary hepatocytes and high-throughput screening.
Competencies
Collaborative - Openness, One Team
Undaunted - Fearless, Can-do attitude
Results Orientation - Delivering progress toward our mission. Sense of urgency in solving problems.
Entrepreneurial Spirit - Proactive. Ownership mindset.
Due to the nature of their work, our manufacturing and lab-based positions are located fully on-site.
Minimum base salary of $122,000 to a maximum base salary of $138,000 + discretionary bonus, equity and benefits.
The range provided is CRISPR Therapeutics' reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities. Consult with your recruiter to determine a more targeted range based on these job-related factors.
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: ***********************************************
Auto-ApplyScientist
Senior principal scientist job in South San Francisco, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
• We are seeking a highly motivated, results-oriented, self-starter who demonstrates personal accountability for outcomes and thrives on increasing levels of responsibility, to join a new and dynamic team responsible for successful development and characterization of clinical-scale manufacturing processes for Chimeric Antigen Receptor T cell (CART) therapies.
• The successful candidate will contribute to the development and implementation of processes for lab-scale production and characterization of high-quality lentiviral vector (LVV) and its application for engineering CART cells.
Job Responsibilities:
• Actively contribute to development and characterization, and successful execution of robust LVV production processes adherent and/ or suspension-based production, purification and formulation.
• Contribute to optimization of LVV transduction for CART manufacturing processes development as appropriate
• Contribute to innovation programs to enhance LVV and CART manufacturing technologies/ capabilities and work-processes as appropriate
• Contribute to Project Technical Teams and communicate and collaborate effectively to ensure effective interactions with all stakeholder groups
• Ensure high-quality, timely documentation in electronic laboratory notebooks and Technical Reports and contribute to Regulatory Filings and responses to Regulatory questions as appropriate.
• Present data/ strategy to scientists (and management) in internal venues (technical meetings, Project Team meetings) as appropriate.
Qualifications
Education & Experience:
BSc/ MSc with 5+ years or PhD degree in Virology/ Molecular Immunology/ Molecular Biology or related field or Chemical Engineering degree (with appropriate viral vector experience); experience with viral vector production/ purification processes and disposable manufacturing technologies a plus.
Technical Skills Requirements:
- Development and/ or execution of LVV/ other viral vector production and purification processes
- Molecular virology/ engineering and/ or production of recombinant viruses
- Culture of primary T cells, T cell molecular biology/ engineering
Additional Skills:BS/MS degree with 5+ years experience required, or PhD
Additional Information
Best Regards,
Anuj Mehta
************
Bench Scientist II
Senior principal scientist job in South San Francisco, CA
We are seeking a results-oriented, self-starter who demonstrates personal accountability for outcomes and thrives on increasing levels of responsibility, to join a new and dynamic team responsible for successful development and characterization of clinical-scale manufacturing processes for Chimeric Antigen Receptor T cell (CART) therapies. The successful candidate will help to develop and qualify analytical methods for the characterization, release and stability testing of CART products. In particular, this position will be responsible for the generation, integration, analysis, an interpretation of multi-parametric flow cytometry data, and from associated technologies, using bulk- and single-cell technologies. He/ she will collaborate with team members and key stakeholders, including the CART Process and R&D groups.
Job Description:
Provide analytical support for clinical-scale non-GMP/ GMP IND-enabling manufacturing operations, including qualification of in-process and release methods, and tech transfer internally and externally, in support of manufacturing and release of clinical material. · Actively contribute to successful development, qualification and execution of robust, state-of-the-art analytical methods for characterization of CART manufacturing processes and products. · Collaborate productively to understand process/ product relationships, enhance product characterization, and help identify critical cellular quality attributes. · Establish strong personal accountability, demonstrate good interpersonal skills, communicate and collaborate effectively with leadership and peers to ensure productive interactions, and contribute to project technical teams to ensure effective integration at all levels. · Apply good organizational skills, and sound scientific and technical experience to establish high-quality lab practices in order to maintain consistent and accurate test data. · Ensure timely documentation in electronic laboratory notebooks, and author/ contribute to technical reports related to regulatory filings/ responses as appropriate. · Regularly present data/ strategy to scientists and management, in internal and external venues, as well as publish in peer-reviewed journals, as appropriate.
Technical skills:
· Extensive multicoloar flow cytometry (FACS)
· Immunology and T cells knowledges.
· Cell biology capability - cryopreservation, cell culture, cytotoxicity, cytokine, proliferation
· Biomarker experience is a plus.
Minimum education experience required:
B.S. +3 years or M.S. + 2 years in cellular biology, biological sciences discipline is preferred preferably in cell-scale studies, along with demonstrated advanced analytical and troubleshooting skills.
· Industry laboratory experience in a variety of analytical methods for the characterization and GMP release of cell-based or gene-related therapies, especially flow cytometry-related immunophenotyping.
· Applied skills in cell biology, particularly in primary T cell culture/expansion and immunologic characterization.
Qualifications
Minimum education experience required:
B.S. +3 years or M.S. + 2 years in cellular biology, biological sciences discipline is preferred preferably in cell scale studies, along with demonstrated advanced analytical and troubleshooting skills.
· Industry laboratory experience in a variety of analytical methods for the characterization and GMP release of cell-based or gene-related therapies, especially flow cytometry-related immunophenotyping.
· Applied skills in cell biology, particularly in primary T cell culture/expansion and immunologic characterization.
Additional Information
All your information will be kept confidential according to EEO guidelines.
Scientist I-Bioanalysis
Senior principal scientist job in South San Francisco, CA
+ The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group. The main function of this position is to develop and implement **LC/MS (liquid chromatography/mass spectrometry)** -based bioanalysis and in vitro characterization assays for biologics entities. The successful candidate will be experienced in the development, optimization and implementation and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of **therapeutic proteins, peptides, and oligonucleotides.** The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
**Responsibilities:**
+ Operate and maintain **LC/MS instruments** to generate high-quality experimental data.
+ Perform affinity purification of therapeutic proteins (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-si RNA conjugates, and fusion proteins) from biological matrices.
+ Analyse data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
+ Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
+ Communicate data interpretation internally and externally.
**Experience:**
+ Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
+ Prior industry experience in drug discovery/development is preferred. In-depth understanding of PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired.
+ Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is highly desired.
+ Hands-on experience with automated liquid handling systems is highly desired.
+ Hands-on experience with oligonucleotide analysis is highly desired.
**Skills:**
+ Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor
+ Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers
+ Experience on routine LC/MS-based bioanalysis to support in vivo PK, TK, and PK/PD studies
**Education:**
+ Degree in chemistry, pharmacology or other related fields. BS with 3+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry.
**About US Tech Solutions:**
US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit *********************** (********************************** .
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Scientist II, In Vivo, Enzymatic and Metabolic Therapeutic Area
Senior principal scientist job in Petaluma, CA
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.
About Worldwide Research and Development
From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.
We are seeking a motivated Scientist with experience in genetic metabolic diseases to join our team. The Scientist will join the Enzymatic and Metabolic In Vivo team to design and execute key in vivo studies focused on developing therapeutics to transform the lives of people with genetic metabolic disorders. This role reports into the In Vivo Lead. The primary role of the Scientist will be in design and execution of in vivo studies as part of the Enzymatic and Metabolic In Vivo Team. They will work collaboratively across the Research and Early Development Department to identify, develop and execute project strategies for in vivo testing of novel therapeutics. Areas of focus will span from animal model development to testing novel therapeutic approaches for genetic metabolic disorders. The successful candidate will have a strong background in metabolic and enzymatic biology, with demonstrated experience in the use of model systems in research. Experience with in vivo models of disease and a collaborative mindset is critical. While some industry experience is a plus, it is not required.
The successful candidate will contribute in vivo model evaluation and support to project teams that support the project goals. Including in vivo study design, hands on in vivo study performance, selection and characterization of animal models, as well as application of in vivo methods and techniques. Strong written communication skills are critical for FDA filings, writing IACUC protocols, communicating scientific strategy, monitoring in vivo studies and collaborating with CRO's, tissue collection, and sample management. The successful candidate will also have experience with in vivo technical tasks including but not limited to dosing techniques (SC, IP, IV, RO, PO), blood collection (tail nick, saphenous vein puncture), and IVIS imaging.
The ideal candidate will have Postdoctoral Academic or Biotech/Pharma industry in vivo experience in the metabolic disease field. The ideal candidate will have hands-on experience with animal models of metabolic/enzymatic disease, a proven track record of high-quality science. Proficiency with in vivo methods such as administration of test articles, perfusion and tissue collection, blood collection, as well as rodent surgical models is required. Candidate level at hire will depend on education and experience.
Responsibilities:
Research Support
* Conduct research on genetic metabolic diseases
* Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients
* Perform research and publish findings in high-impact journals and present research at major conferences
* Effectively partner with other scientists and the Research and Early Development team to develop and execute on the program's strategic plan
* Present program data at a range of internal forums, including project team meetings, Research Department Seminars and Research leadership governance forums
* Write, review and contribute to study synopses, protocols, study reports and regulatory documents
* Collaborate with various BioMarin functions, CROs, university or analytical laboratories, business partners, as necessary to ensure appropriate/timely progression of projects
* Participate in multi-disciplinary drug development teams and may lead sub-teams
* Excellent written and verbal communication
* Ability to build/foster productive cross-functional collaborations both within and external to BioMarin
* Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, willalso be required.
* Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation.
* Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal clinical studies.
* Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines.
* Share your knowledge and understanding with other team members
* Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs.
* Other duties as assigned.
* Willingness to work on site full time including off hours and weekends based on study needs.
* Other duties as assigned.
General requirements for the position:
* Demonstrated experience in metabolic biology/disease research in academia or industry (preferred) including publication record
* Strong analytical, problem-solving, and decision-making skills
* Strong understanding of genetically engineered models, breeding, and management and Gene therapy modalities
* Excellent oral and written communication skills
* Passion for contributing your scientific skills to develop therapies for patients in need
* Must be able to utilize computer databases for analysis, data entry, and point of care observations
* Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams
* Must be able to work with external regulatory agencies and accreditation groups
* Some "off-core business hours" work required
* Complete all company training requirement
* Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks
* This position is an on-site critical required position
* Other duties as assigned
Education and Experience Requirements:
* PhD in a related subject area with demonstrated in vivo research experience in metabolic disease
* Postdoctoral or industry (2-5 years preferred) experience in genetic metabolic diseases
* Extensive hands-on experience with rodent in vivo work in the metabolic field
This position is full-time on-site and based in Petaluma, CA with occasional work on site in San Rafael, CA
Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.
Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
The salary range for this position is: $116,000 to $159,500. BioMarin considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans.
For additional benefits information, visit:
After School Program Mad Scientist
Senior principal scientist job in Sacramento, CA
Become a Mad Science Instructor… …the most fun job you'll ever have! Mad Science is the leading enrichment provider in the Sacramento area. We provide after school programs, workshops, shows, science nights, camps and parties for children ages 3-12. We are now hiring After School Program instructors, part-time!
All you need is some experience with children, high ENERGY, a car and a desire to inspire!
This is Elementary school science…but we will train you.
From chemistry to bugs, and planets to robots, plus so much more…you have the opportunity to teach it all!
Compensation per after school program: starting at $31 plus mileage reimbursement Compensation: $17.00 - $35.00 per hour
Mad Science is a powerhouse brand with locations around the globe! For over 35 years, we have sparked imaginative learning through our summer camps, birthday parties, in-class workshops, after-school programs, and special events for kids ages 3-12. Become part of our team and help us inspire the next generation of scientists and engineers. Our locations are always looking for part-time instructors and full-time office staff.
Auto-ApplyResearch Scientist
Senior principal scientist job in San Francisco, CA
Applied Scientist
Package - > $200 - 250k Cash + Benefits
A scaling, SOTA Generative AI Startup operating with a world class team (Founders have multiple prior exits) with talent from Open AI, IBM, MIT and several top orgs, focused on pioneering work and advancements in large language models (LLMs), code generation, and code translation. Their projects directly involve industry leading partners where they're applying advanced AI to solve meaningful, practical challenges with real-world impact.
Broad Responsibilities:
Design, execute, and analyze experiments with a high degree of independence
Contribute to core models and frameworks
Create high-quality datasets (both in-the-wild and synthetic)
Perform literature reviews and implement new techniques from papers
Contribute to publications, present at conferences and workshops, etc.
Requirements:
Ph.D. in Computer Science or another STEM subject
Prior LLM research experience
Comfortable programming in Python and familiar with frameworks such as PyTorch and HuggingFace
Preferred Qualifications:
Publications at peer-reviewed conferences such as NeurIPS, ICLR, ICML, etc.
Experience with large-scale LLM training, particularly in a distributed computing environment
Get in touch today for more details and immediate consideration / interview!
Research Scientist
Senior principal scientist job in San Francisco, CA
About the Company
We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks.
About the Role
As a Research Scientist, you will develop new benchmarks, methodologies, and evaluation pipelines that shape how cutting-edge models are assessed, compared, and deployed in production environments. Your work will directly influence model selection and safety decisions across foundation model labs, high-growth AI product companies, and Fortune-scale enterprises.
Responsibilities
Benchmarking & Model Analysis
Evaluate newly released models as they launch (e.g., Gemini, DeepSeek, etc.)
Run large-scale assessment workflows using internal evaluation infrastructure
Compare model performance across enterprise-grade task categories
Design New Benchmarks from Scratch
Identify high-value model application domains through research exploration
Construct datasets, including labeling strategy and workforce coordination
Write short “white-paper-style” summaries explaining benchmark purpose, method, and findings
Advance Automated Evaluation Methodologies
Improve systems for scoring generated text beyond standard metrics
Explore research in reference-free, rubric-based, and human-aligned evaluation
Develop new techniques for reliability, consistency, and repeatability
Cross-functional Collaboration
Work closely with engineering to scale evaluation infra
Partner with customers to refine evaluation relevance and task fit
Influence product direction through research insights
Qualifications
0-3 years post-grad experience (Master's, PhD, or equivalent applied research)
Publications, preprints, or demos showing cutting-edge work
Experience with diffusion models, NLP, multimodal, or benchmarking work
Ability to operate independently with ambiguity
Clean, maintainable research codebases
Candidates from:
top engineering/research universities
applied AI startups
well-regarded research internships
Required Skills
Built or contributed to a benchmark or evaluation methodology
Experience in enterprise task model evaluation
Stanford / top lab adjacency (per their historical hiring success)
Preferred Skills
Wants to publish as primary motivation
Purely academic with slow timelines
Big-tech culture fit concerns (Meta / Google / Salesforce specifically noted-but case-by-case)
Pay range and compensation package
Base Salary: up to $250K depending on background
Equity: typically 0.3% - 0.5%, flexibility for exceptional candidates
Rapid equity refresh possible based on impact
Equal Opportunity Statement
Visa sponsorship available. Relocation support. Health & dental coverage. Lunch + dinner provided, snacks & coffee. Unlimited PTO. Weekly happy hours with community guests. Team events (bowling, hiking, rock climbing, etc.). Swag program (hats, etc.).
Work Environment & Culture
In-person, San Francisco HQ (required). Core hours: 9-5, some teammates extend voluntarily. Most team members work 1 weekend day per week (flexible). High-ownership, low-ego, collaborative. Live demos Mondays, team lunch Thursdays, community Fridays. Early-stage pace, applied focus-not academic publishing.
Tech Environment
(while research-focused, exposure beneficial) Backend: Python / Django. Frontend: React + TypeScript. Infra: AWS. Evaluation frameworks + internal tooling.
Why This Role Is Unique
The company already collaborates with foundation model labs, high-growth AI vertical product companies, and Fortune 500 enterprises (not publicly facing). ChatGPT Vals AI $5M seed raised, runway of 2+ years at current burn. Only one research scientist is being hired-true founding impact. Opportunity to define industry standards for model trust, reliability, and certification. Positioned to become the rating agency for generative AI.
Research Scientist
Senior principal scientist job in San Francisco, CA
We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring a Research Scientist on a hybrid basis.
They have seen $300M in a recent fund raise.
Skills targeted:
PhD in Physics/ Quantum Physics/ Theory/ Statistics/ Mathematics/ Computational Science or similarly related field.
2+ YoE working with AI Agents.
Good exposure to LLMs.
TC package of $1-1,5M with sizeable base salary & equity package.
If that looks of interest, apply & Goliath will be in touch!
Scientist/Sr. Scientist-Stem Cell Biology/Embryology
Senior principal scientist job in San Francisco, CA
located in San Francisco, CA
Responsibilities of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology:
Design and execute experiments in stem cell differentiation, organoid generation, and tissue engineering.
Innovate then execute experiments to generate and differentiate human stem cells, develop functional assays, assess and interpret experimental workflows
Perform mammalian embryo dissections, tissue isolations, and culture experiments to study and model developmental processes.
Apply principles of developmental biology and embryology to guide tissue maturation and patterning.
Collaborate with biomaterials and engineering teams to integrate cells and tissues.
Develop and optimize protocols for reproducible tissue generation and maintenance.
Test novel stem cell culture conditions, sort, screen, expand and differentiate hi PSCs according to latest protocols and newly developed approaches.
Requirements of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology:
PhD in biological sciences, stem cell biology, genetics or related field.
2+ years hands-on expertise in stem cell culture (iPSCs/ESCs).
Hands-on experience with mammalian embryos, including dissections and culture.
Experience in molecular biology and strong problem solving skills.