Senior principal scientist jobs in New Bedford, MA - 361 jobs

Application deadline: Applications will be accepted on an ongoing basis Amazon Ads is re-imagining advertising through cutting-edge generative artificial intelligence (AI) technologies. We combine human creativity with AI to transform every aspect of the advertising life cycle-from ad creation and optimization to performance analysis and customer insights. Our solutions help advertisers grow their brands while enabling millions of customers to discover and purchase products through delightful experiences. We deliver billions of ad impressions and millions of clicks daily, breaking fresh ground in product and technical innovations. If you're energized by solving complex challenges and pushing the boundaries of what's possible with AI, join us in shaping the future of advertising. Why you'll love this role: This role offers unprecedented breadth in ML applications and access to extensive computational resources and rich datasets that will enable you to build truly innovative solutions. You'll work on projects that span the full advertising life cycle, from sophisticated ranking algorithms and real-time bidding systems to creative optimization and measurement solutions. You'll work alongside talented engineers, scientists, and product leaders in a culture that encourages innovation, experimentation, and bias for action, and you'll directly influence business strategy through your scientific expertise. What makes this role unique is the combination of scientific rigor with real-world impact. You'll re-imagine advertising through the lens of advanced ML while solving problems that balance the needs of advertisers, customers, and Amazon's business objectives. Your impact and career growth: Amazon Ads is investing heavily in AI and ML capabilities, creating opportunities for scientists to innovate and make their marks. Your work will directly impact millions. Whether you see yourself growing as an individual contributor or moving into people management, there are clear paths for career progression. This role combines scientific leadership, organizational ability, technical strength, and business understanding. You'll have opportunities to lead technical initiatives, mentor other scientists, and collaborate with senior leadership to shape the future of advertising technology. Most importantly, you'll be part of a community that values scientific excellence and encourages you to push the boundaries of what's possible with AI. Watch two Applied Scientists at Amazon Ads talk about their work: ********************************** HsURsIPEA Learn more about Amazon Ads: ******************************* Key job responsibilities As a Senior Applied Scientist in Amazon Ads, you will: - Research and implement cutting-edge ML approaches, including applications of generative AI and large language models - Develop and deploy innovative ML solutions spanning multiple disciplines - from ranking and personalization to natural language processing, computer vision, recommender systems, and large language models - Drive end-to-end projects that tackle ambiguous problems at massive scale, often working with petabytes of data - Build and optimize models that balance multiple stakeholder needs - helping customers discover relevant products while enabling advertisers to achieve their goals efficiently - Build ML models, perform proof-of-concept, experiment, optimize, and deploy your models into production, working closely with cross-functional teams including engineers, product managers, and other scientists - Design and run A/B experiments to validate hypotheses, gather insights from large-scale data analysis, and measure business impact - Develop scalable, efficient processes for model development, validation, and deployment that optimize traffic monetization while maintaining customer experience Basic Qualifications - 5+ years of building machine learning models for business application experience - PhD, or Master's degree and 6+ years of applied research experience - Experience programming in Java, C++, Python or related language - Experience with neural deep learning methods and machine learning Preferred Qualifications - Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc. - Experience with large scale distributed systems such as Hadoop, Spark etc. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The Colorado base pay for this position ranges from $167,100/year up to $226,100/year. The National base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************* . This position will remain posted until filled. Applicants should apply via our internal or external career site.

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Responsibilities Partner with our pharma clients to design, develop and execute computational research leveraging the Tempus platform to advance drug R&D programs. Become an expert in Tempus multimodal clinical and genomic data. Analyze and integrate large, diverse clinical and molecular datasets to extract insights and drive new research opportunities. Lead scientific and technical interactions with clients to co-architect solutions and projects. Become an expert in current and prospective clients' strategies, pipelines, and portfolios to identify where the Tempus platform can add value and collaborate with sales teams to realize that value. Collaborate with Research, Engineering & Data Science teams to develop and deliver innovative computational solutions. Drive continual improvement of the Tempus platform by communicating client feedback, staying ahead of research and industry trends, championing opportunities for new markets, and influencing our leadership and global account strategy teams. Work with Product and Engineering teams to streamline the workflow of computational analyses. Document, summarize, and communicate highly technical results and methods clearly to non-technical audiences. Author whitepapers and peer-reviewed manuscripts illustrating the value of multimodal analysis and AI in drug discovery. Qualifications Education to Masters or Ph.D. level combining quantitative and/or computational skills, e.g., Computational Biology, Biostatistics/Statistical Genetics, Bioinformatics, Biomedical Informatics, Biometrics, Data Science for Health, or similar. Biological or medical knowledge, e.g., Human Disease, Genetics/Genomics, Molecular Biology, or Immunology. Comfort in a client-facing role. Proficient in R or Python. Strong understanding of the molecular nature of human disease. Expert in delivering actionable insight from transcriptomic data sets. Experience with Clinical Trial Data and/or Real World Evidence. Experience with integrative methods to model multi-modal clinical and/or omics data. Experienced in SQL. Thrive in a fast‑paced environment and willing to shift priorities seamlessly. Experience in any of the following will also be beneficial: drug R&D oncology; immunology; single cell or spatial transcriptomics; mechanistic modeling and inference; knowledge and graph‑based AI techniques. CHI: $170,000-$230,000 NYC/SF: $180,000-$250,000 The expected salary range above is applicable if the role is performed from Massachusetts and may vary for other locations (California, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. Massachusetts Applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. #J-18808-Ljbffr

A global biotechnology company seeks an experienced Associate Principal Scientist to support in vitro pharmacology projects. The role involves collaborating with pharmacologists, managing CRO relationships, and assessing external resources for early drug discovery. The ideal candidate should possess a relevant Bachelor's degree and extensive industry experience. A hybrid work model is offered. Competitive salary range from $144,800 to $227,900 annually. #J-18808-Ljbffr

A consulting firm specializing in healthcare seeks a Senior Consultant in Boston, MA. The role involves managing research efforts, mentoring junior consultants, and providing strategic insights to clients. Candidates should have an advanced degree or relevant experience in life sciences consulting, strong data synthesis abilities, and excellent communication skills. The position offers a competitive salary starting at $128,000 plus bonus potential, making it an attractive opportunity for professionals in the biopharmaceutical industry. #J-18808-Ljbffr

Title: Senior Research Associate - Cell & Gene Therapy (Analytical Development) Employment Type: Contract (12 months) Status: Accepting Candidates About the Role Join a fast-paced Cell & Gene Therapy analytical development team supporting preclinical and clinical programs. This role is hands-on and bench-focused, contributing directly to assay execution, data generation, and process development. Key Responsibilities Perform routine analytical testing to support process development, characterization, and release assays Execute cell-based and plate-based assays including potency, ELISA, MSD, and molecular assays Conduct Flow Cytometry, qPCR/PCR, and mammalian cell culture experiments Document experiments in Benchling ELN and maintain clear, compliant records Support sample handling, inventory tracking, and cross-functional collaboration Qualifications BS with 5+ years or MS with 3+ years of industry experience (PhD not required) Background in Cell & Gene Therapy, biotech, or biologics Strong hands-on experience running bench experiments independently Proficiency with Flow Cytometry, plate reader assays, and cell culture Experience in Analytical Development within a regulated lab environment Compensation (MA Pay Transparency): Estimated hourly range: $40-$48/hr (W-2) Final rate within this range will be based on skills, experience, and interview results.

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss. The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group. The position is responsible for all aspects of project management including project proposals, execution, and reporting. The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce. #FMG #LI-TA1

Associate Principal Scientist, Process Chemistry FLSA Status: Exempt Salary: $130,000-$160,000 Pharmaron is thrilled to invite you to join us as our newest Associate Principal Scientist at our Coventry, RI facility! If you're craving a role that offers challenges, growth, and meaningful impact, then this is the opportunity you've been waiting for. Job Overview: The Associate Principal Scientist is a subject matter expert within Process Chemistry and is responsible for solving highly complex chemical development problems for ground-breaking Active Pharmaceutical Ingredient (API) development projects: Responsibilities: Design and execute core experiments, interpret results, and plan additional experiments in a timely manner to solve assigned problems of high complexity. Demonstrate expertise in the core chemistry laboratory skills required to support development and / or scale up of chemical processes Actively participate in the development of new technologies or methodologies Effectively communicate, coordinate and collaborate with cross-functional project groups to ensure that scientific work is appropriately documented such that the broader collaborative inputs and efforts are combined to maximum effect in the production of reports, manuscripts, and presentations. Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable, which may include significant contributions to manufacture of API for GLP toxicology studies or for GMP manufacture of clinical supplies. Contribute to effective team planning and mentor less experienced staff on core functional technical and procedural matters as opportunities arise. Follow all key internal business practices and external regulations governing the role (e.g. GLP or GMP), and adhere to all corporate policies governing the business activities. What We're Looking For: PhD in Chemistry or related field. Multi-year industrial experience within relevant role Evidence of experience in successful application of analytical / physical skill sets to resolve high complexity chemical problems Evidence of ability to effectively contribute to multi-disciplinary scientific teams Competency in the routine use of core instrumentation and laboratory techniques and higher end instrumentation and laboratory techniques. Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues Ability to work cross-functionally and manage projects effectively Excellent organizational, planning and time management skills Why Pharmaron? Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Who we are: The Search and Recommendations Machine Learning (ML) team is at Wayfair is at the forefront of designing and implementing algorithms that define our global search experience. Using cutting-edge machine learning approaches-including deep sequence models, embeddings and multi-modal technologies-we aim to deliver a personalized and compelling experience for over 22 million active customers. Our mission is to make the user experience intuitive and efficient, helping customers discover exactly what they need in a vast and diverse product catalog. What You'll Do: * Elevate recommendation quality: Design and implement scalable machine learning models to improve the ranking, and personalization of product recommendations across Wayfair * Develop robust retrieval systems: Build and optimize candidate generation pipelines that surface high-quality, personalized product recommendations at scale. * Leverage user and product signals: Apply deep learning and representation learning to model user preferences, product attributes, and contextual signals for better recommendation performance. * Innovate with cutting-edge techniques: Explore sequence modeling, embeddings, and multi-modal modeling to drive the next generation of recommender systems. * Collaborate cross-functionally: Partner with product managers, engineers, and data scientists to align recommendation strategies with business objectives and user needs. * Tackle recommendation-specific challenges: Solve key issues such as the cold-start problem, data sparsity, product compatibility and seasonality in dynamic environments. * Advance the ML community at Wayfair: Contribute to internal knowledge sharing, author technical documentation, and represent Wayfair at top ML conferences like NeurIPS and RecSys. Who You Are: * Bachelor's or advanced degree (Master's, PhD) in Computer Science, Machine Learning, Mathematics, Statistics, or related field. * 4+ years of industry experience as an ML engineer, applied scientist, or research scientist, with a proven track record of delivering ML projects autonomously and driving measurable business impact, particularly in recommendations, search, or ranking. * Expertise in recommendation systems, including candidate generation, ranking algorithms, and user-item modeling. * Deep understanding of collaborative filtering, sequence modeling, and embedding-based personalization. * Experience with end-to-end project ownership, including collaboration with business partners and strong written and verbal communication skills. * Strong proficiency in Python and/or Java for building and deploying ML-driven recommendation systems. * Experience deploying machine learning models in production environments, with a focus on cloud-based solutions such as GCP (BigQuery, GCS, Vertex AI, Composer), as well as workflow orchestration tools like Airflow, model tracking using MLflow, and containerization technologies like Docker. Why You'll Love Wayfair: * Time Off: * Paid Holidays * Paid Time Off (PTO) * Health & Wellness: * Full Health Benefits (Medical, Dental, Vision, HSA/FSA) * Life Insurance * DIsability Protection (Short Term & Long Term DIsability) * Global Wellbeing: Gym/Fitness discounts (including US Peloton, Global ClassPass, and various regional gym memberships) * Mental Health Support (Global Mental Health, Global Wayhealthy Recordings) * Caregiver Services * Financial Growth & Security: * 401K Matching (Employee Matching Program) * Tuition Reimbursement * Financial Health Education (Knowledge of Financial Education - KOFE) * Tax Advantaged Accounts * Family Support: * Family Planning Support * Parental Leave * Global Surrogacy & Adoption Policy * Professional Development & Recognition: * Rewards & Recognition * Global Employee Anniversary Awards * Paid Volunteer Work * Unique Perks: * Employee Discount * U.S. Bluebikes Membership * Global Pod Outings * Work/Life Balance: * Emphasizing a supportive & flexible work environment that encourages a balance between personal and professional commitments If you don't meet every qualification listed, we still encourage you to apply. We're looking for strong team players who can learn, grow, and make an impact. This is a hybrid position located in Boston, MA. The team is in-office Tuesday-Thursday and remote on Monday and Friday. Assistance for Individuals with Disabilities Wayfair is fully committed to providing equal opportunities for all individuals, including individuals with disabilities. As part of this commitment, Wayfair will make reasonable accommodations to the known physical or mental limitations of qualified individuals with disabilities, unless doing so would impose an undue hardship on business operations. If you require a reasonable accommodation to participate in the job application or interview process, please let us know by completing our Accomodations for Applicants form. Need Technical Assistance? For more information about applying for a career at wayfair, visit our FAQ page here. About Wayfair Inc. Wayfair is one of the world's largest online destinations for the home. Whether you work in our global headquarters in Boston, or in our warehouses or offices throughout the world, we're reinventing the way people shop for their homes. Through our commitment to industry-leading technology and creative problem-solving, we are confident that Wayfair will be home to the most rewarding work of your career. If you're looking for rapid growth, constant learning, and dynamic challenges, then you'll find that amazing career opportunities are knocking. No matter who you are, Wayfair is a place you can call home. We're a community of innovators, risk-takers, and trailblazers who celebrate our differences, and know that our unique perspectives make us stronger, smarter, and well-positioned for success. We value and rely on the collective voices of our employees, customers, community, and suppliers to help guide us as we build a better Wayfair - and world - for all. Every voice, every perspective matters. That's why we're proud to be an equal opportunity employer. We do not discriminate on the basis of race, color, ethnicity, ancestry, religion, sex, national origin, sexual orientation, age, citizenship status, marital status, disability, gender identity, gender expression, veteran status, genetic information, or any other legally protected characteristic. Your personal data is processed in accordance with our Candidate Privacy Notice (***************************************** If you have any questions or wish to exercise your rights under applicable privacy and data protection laws, please contact us at *********************************.

: The Associate Principal Scientist is responsible for meeting the analytical testing requirements to support research and development projects primarily focused on oligonucleotides. Key Responsibilities: Supervise/manage staff as needed. Design and/or execute testing per method or protocol for development, qualification, verification, validation, and transfer of analytical methods for multiple projects. Analyze and review project data, correct errors, and report results for multiple projects to support research and development primarily focused on oligonucleotides. Perform GDP, technical, and gap analysis review and investigations across multiple projects. Author and approve scientific and regulatory documentation. Provide professional scientific leadership in all internal and external interactions. Improve laboratory compliance. Design, review, perform, and improve method development experiments and strategies. Propose, develop and implement new analytical applications and technology. Provide advanced-level training internally and externally. Plan, track, execute, and review multiple project team tasks to deliver project results on time. Exercise independent judgment in developing methods, techniques, and evaluation criteria for obtaining results. Communicate with clients and resolve issues in consultation with laboratory management. Interview candidates and advise management on hiring. Develop and lead implementation of department objectives for continuous improvement and technical excellence. Advise clients on analytical scope to meet technical and regulatory requirements. Review BD customer proposals. Required Skills/Abilities: BA/BS with 12+ yrs. of related experience. MS with 9+ yrs. of related experience. PhD with 6+ yrs. of related experience. Subject matter expert analytical chemistry knowledge including theory and application of two or more chromatographic and spectroscopic techniques for identification, purity, and assay of various analytes. Operate and troubleshoot available instruments including HPLC and MS. Review and approve outsourced method development and validation. Application of chemistry and oligonucleotide knowledge to method development and solving complex problems independently. Advanced Word, Excel and PowerPoint. Perform advanced algebraic and statistical calculations correctly. Proficient in technical writing and presentations to internal and external audiences. Author, revise, and approve laboratory and systemic SOPs. Competency to think strategically and conceptually to apply quality by design principles when designing experiments. Perform method gap and error analyses. Knowledge and application of cGMPs and regulatory guidance documents. Knowledge of Oligonucleotide chemical and physical properties. Current methods to characterize oligonucleotides. Remain abreast of emerging analytical technologies in the oligonucleotide field. The annualized salary range for this position is $140,800.00 - $172,200.00.

About this opportunity : The Associate Principal Scientist is responsible for meeting the analytical testing requirements to support research and development projects primarily focused on oligonucleotides. Key Responsibilities: * Supervise/manage staff as needed. * Design and/or execute testing per method or protocol for development, qualification, verification, validation, and transfer of analytical methods for multiple projects. * Analyze and review project data, correct errors, and report results for multiple projects to support research and development primarily focused on oligonucleotides. * Perform GDP, technical, and gap analysis review and investigations across multiple projects. * Author and approve scientific and regulatory documentation. * Provide professional scientific leadership in all internal and external interactions. * Improve laboratory compliance. * Design, review, perform, and improve method development experiments and strategies. * Propose, develop and implement new analytical applications and technology. * Provide advanced-level training internally and externally. * Plan, track, execute, and review multiple project team tasks to deliver project results on time. * Exercise independent judgment in developing methods, techniques, and evaluation criteria for obtaining results. * Communicate with clients and resolve issues in consultation with laboratory management. * Interview candidates and advise management on hiring. * Develop and lead implementation of department objectives for continuous improvement and technical excellence. * Advise clients on analytical scope to meet technical and regulatory requirements. * Review BD customer proposals. Required Skills/Abilities: * BA/BS with 12+ yrs. of related experience. * MS with 9+ yrs. of related experience. * PhD with 6+ yrs. of related experience. * Subject matter expert analytical chemistry knowledge including theory and application of two or more chromatographic and spectroscopic techniques for identification, purity, and assay of various analytes. * Operate and troubleshoot available instruments including HPLC and MS. * Review and approve outsourced method development and validation. * Application of chemistry and oligonucleotide knowledge to method development and solving complex problems independently. * Advanced Word, Excel and PowerPoint. * Perform advanced algebraic and statistical calculations correctly. * Proficient in technical writing and presentations to internal and external audiences. * Author, revise, and approve laboratory and systemic SOPs. * Competency to think strategically and conceptually to apply quality by design principles when designing experiments. * Perform method gap and error analyses. * Knowledge and application of cGMPs and regulatory guidance documents. * Knowledge of Oligonucleotide chemical and physical properties. * Current methods to characterize oligonucleotides. * Remain abreast of emerging analytical technologies in the oligonucleotide field. The annualized salary range for this position is $140,800.00 - $172,200.00.

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients. Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits. Today, Strand has established multiple programmable mRNA platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a Phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts. Become the next standout single strand! Job Summary: Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Scientist of LNP Discovery. The expectation is that the candidate will have experience in the world of LNP discovery research particularly focused on the successful delivery of nucleic acid payloads. Reporting to the Principal Scientist of LNP Discovery, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a deep scientific knowledge. Primary Responsibilities: Help advance Strand's mRNA delivery platform and capabilities. Lead and contribute to lipid innovation and development/optimization of lipid nanoparticle (LNP) formulations. Characterize the physicochemical properties and evaluate therapeutic indices of (lipid) nanoparticle formulations using standard or newly developed in-house assays. Execute LNP composition optimization and screening assays. Produce (lipid) nanoparticle formulations to support internal and partnered programs. Compile data reports and communicate the results with relevant team(s). Research and identify new opportunities and novel project ideas related to mRNA delivery that support Strand's vision. Maintain and establish new relationships with outside collaborators which provide access to proprietary (lipid) nanoparticles. Write study protocols, technical reports and SOPs that support the drug discovery efforts of Strand. Interact with IP counsel/consultants to assist with patent prosecution. Qualifications: B.S. or Advanced Degree with 6-7+ years of industry experience with a focus on lipid chemistry, nanoparticle formulation and in vivo delivery of nucleic acid-based payloads. Experience with lipid chemistry required. Experience with production and analytical characterization of (lipid) nanoparticles required. Prior experience with (high throughput) screenings of (lipid) nanoparticles preferred. Prior experience with development of tissue/cell targeting (lipid) nanoparticles would be a plus. Excellent knowledge of the scientific literature in the field of mRNA delivery. Demonstrated experience working across internal and external research teams. Highly analytical, decisive, and goal-oriented while maintaining the highest scientific and ethical standards. Ability to quickly adapt to change and thrive in a dynamic and entrepreneurial early-stage environment. A strong team player with excellent oral and written communication skills and a demonstrated ability to work independently. Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand's goals. Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates. Job Type: Full-time Salary: $100,000 - $140,000 annually plus bonus and equity incentives Pay Transparency Base Salary Range $100,000 - $140,000 USD

SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team is seeking an exceptional Scientist, Molecular AI Architecture to pioneer the convergence of biological computation, large-scale multimodal foundation models, and explainable AI architectures. This visionary role will drive next-generation materials discovery by developing novel AI systems. Essential Duties and Responsibilities: AI Architecture & Design: Architect novel AI systems and deep neural architectures (e.g., Transformers, CNNs) inspired by principles of systems neuroscience and neural coding principles. Design and implement large-scale multimodal foundation models and agentic AI systems capable of complex reasoning over molecular and battery datasets. Develop methods for model interpretability, representation engineering, and causal reasoning to ensure AI results are explainable and trustworthy for materials science. High-Performance Computing & Efficiency Lead software development efforts for high-performance computing (HPC), focusing heavily on GPU programming and scaling the training and inference efficiency of large neural networks. Optimize complex ML frameworks (like JAX) within systems and cluster computing environments (e.g., Singularity). Scientific ML Integration Create automated data-labeling and behavioral encoding models specifically designed to enhance Molecular AI training and data efficiency. Apply Scientific ML principles to complex molecular and battery datasets, translating biological computation concepts into practical AI solutions for materials discovery. Education and/or Experience: Education: Ph.D. in Computational and Systems Biology, Computational Neuroscience, or a closely related quantitative field. Core Expertise: Deep, demonstrated expertise in systems neuroscience, machine learning, and the design and implementation of deep neural architecture. HPC Software: Proven experience with software development for High-Performance Computing (HPC) environments, including expert-level GPU programming. Model Design: Practical experience in designing and training foundation models and working with concepts like multi-agent reasoning models. Interpretability Focus: Demonstrated work in model interpretability and representation engineering applied to complex scientific data. Preferred Qualifications: Specialized Frameworks: Practical experience with advanced mathematical and machine learning frameworks like JAX and Julia. Advanced Techniques: Expertise in Bayesian inference and working within specialized container/computing environments like Singularity. Advanced AI: Experience with the design and application of agentic AI systems and multimodal reasoning architectures.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. The LIGM RNA Group is seeking an experienced analytical scientist with extensive hands-on experience in analytical techniques for characterizing and analyzing small molecules, biologics, and/or oligonucleotides. The ideal candidate will have a proven track record in analytical method development and troubleshooting, as well as experience with liquid chromatography, (high resolution) mass spectrometry, and other advanced analytical techniques. They must possess strong technical problem-solving skills, be computer savvy with the ability to navigate multiple instrument control programs and data analysis environments, and be able to work independently to achieve efficient, quality results in a fast-paced environment. Responsibilities: Work closely with the chemistry team to source, explore, and implement the latest separation science and analytical technologies for the purification and characterization of oligonucleotides and their conjugates, including carbohydrates, lipids, peptides, and proteins. Conduct LC and LC-MS based method development for sensitive characterization of biologics including intact mass, reduced mass, peptide mapping, and glycan mapping to provide better understanding of attributes. Conduct semi-preparative and preparative method development activities to advance downstream processing for challenging modified oligonucleotides, utilizing RP purification, ion-exchange chromatography, spin filtration, TFF, FPLC, size exclusion chromatography, and MS-direct auto-scale preparative LC-MS techniques. Work with contractors and third-party vendors to troubleshoot and maintain lab instruments, including but not limited to UPLC, LC-MS, osmometer, and NanoDrop, ensuring they remain in peak operational condition. Learn new technologies quickly and apply effective scientific concepts and methods across multiple areas. Process and present data leveraging Microsoft Office apps, GraphPad and Spotfire for data organization and data visualization. Document experiments, data, technical reports, and findings electronically in an accessible manner with good documentation practices. Present findings, progress, and data proactively and regularly in group and department meetings. Possess a collaborative and willing-to-share mindset with excellent verbal and written communication skills, presentation skills, and attention to detail. Ability to follow Global Health, Safety & Environment Center (HSE) guidelines while performing tasks. Basic Qualifications: Bachelor's or Master's degree in Analytical Chemistry, Biochemistry, Chemistry, Food Science, or a related scientific field, with over 2 years of relevant post-graduate experience in industry. Additional Skills/Preferences: Strong analytical thinking skills with a demonstrated ability to articulate issues and extract and synthesize complex information into key focus areas. Extensive experience in operating and troubleshooting a range of mass spectrometers including Q-ToF, QQQ and Orbitrap Proficient with Thermo XCalibur, Agilent ChemStation and MassHunter software. Understanding tandem mass spectrometry and interpretation of MS/MS based characterization of including but not limited to peptide, peptide-oligonucleotide conjugates, and lipid conjugates. Extensive hands-on experience in downstream workflows for small molecules, biologics, and oligonucleotides. Experience with antibody-drug-conjugates (ADCs) or antibody-oligonucleotide-conjugates (AOCs) is a plus. Proven expertise in liquid chromatography including ion-pair reverse phase liquid chromatography as well as ion chromatography. Prior experience in native mass spectrometry and understanding of electrospray ionization as well as molecular behavior in the gas phase. Prior experience in proteomics, bioanalysis, and/or CMC is a significant advantage. Highly self-motivated and self-driven attitude with ability to own and drive projects into success. Strong organizational and communication skills and effective people skills. Capable of continuous learning, open-minded, highly organized, and detail oriented. Ability to balance multiple activities, prioritize and handle ambiguity. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

The Center for Cancer Genomics (CCG) at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. + Performs complex informatics tasks independently + Data analysis, data management, data visualization, or processing of large-scale biological, medical, and/or operational data + Generation of professionally written and graphical reports + Manages ongoing stakeholder/client interactions + Uses peers, academic literature, and online resources for troubleshooting + Works easily with others as part of a larger project team + Contributes expertise to DFCI software code base and communities of practice + Maintains a set of software tools or databases used by others and instructing others in their use **KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:** + Computational and data analysis: Expert + Data management and/or software engineering: Expert + Collaboration and communication: Able to set appropriate expectations, discuss and present results to customers in formal settings, and share ideas accurately and communicate them effectively, both in writing and verbally + Contributes to the development and growth of others + Strong interpersonal skills, ability to effectively interact with all levels of staff and external contacts + Excellent analytical, organizational and time management skills **MINIMUM JOB QUALIFICATIONS:** The position requires a bachelor's degree in a STEM field, with a master's or PhD strongly preferred in areas like bioinformatics, computational biology, or related quantitative fields. Candidates must have 3 years of experience, though a master's degree with 1 year of experience or a PhD with no experience also qualifies. **SUPERVISORY RESPONSIBILITIES:** None **PATIENT CONTACT:** None At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEO Poster** . Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA). $83,800.00 - $90,800.00

About the Opportunity The Bioinformatician will report to Ayan Paul, Research Scientist at EAI, and collaborate with Scientists and Clinicians from Peter Castaldi's group at the Harvard Medical School, John Platig's Network Biology group at the University of Virginia, and Jennifer Dy's group at ECE, Northeastern University. Responsibilities will include building an ETL pipeline for ENCODE genomics data, writing Python code for data analysis, and a downstream R pipeline for post-processing data using standard Bioinformatics libraries from Bioconductor. There will be opportunities to participate in building machine learning models, co-author publications, and contribute to grant proposals. Tentative start date: January 2024 for the Spring 2024 semester with possibilities of renewal. This work will contribute towards the understanding of genetic origins of complex diseases like Chronic Obstructive Pulmonary Disease and cutting-edge machine learning-based methodologies for regulation of mRNA splicing. RESPONSIBILITIES INCLUDE: Building ETL pipelines for genomics/transcriptomics data from public databases and processing them with publicly available codes in python and R. Documenting the entire process and all the codes generated and maintaining structured and regular commits in a GitHub repository. Helped implement machine learning models and automate the processing of input data. Write reports/prepare slide decks describing work performed. Contribute to scientific manuscripts and grant proposals where appropriate. MINIMUM QUALIFICATIONS: A Master's degree (or equivalent) A minimum of 3-4 years of experience working with data pipelines and data analysis. Proficiency in Python and R. Experience working in Unix OS and remote computing clusters. Have demonstrable expertise in bioinformatics, especially genomics, transcriptomics, proteomics and/or metabolomics, and have a good grasp of statistics. Experience working with genomics databases like ENCODE and familiarity with RNA-seq, eCLIP, and other data is highly desirable but not required. An ability to write clean and well-documented code and work with GitHub repositories. Position Type Temporary Additional Information Northeastern University considers factors such as candidate work experience, education and skills when extending an offer. Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation. Visit ************************************* for more information. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law. Pay Rate: $45/hour

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

A leading healthcare technology firm in Boston seeks an Associate Principal Scientist to advance drug R&D through computational research. The ideal candidate will leverage the Tempus platform to analyze diverse datasets, ensuring actionable insights for clients. This role requires a Masters or Ph.D. in areas like Bioinformatics or Data Science, proficiency in R or Python, and comfort in client interactions. A competitive salary range of $170,000-$230,000 reflects the expertise required for this role, alongside comprehensive benefits. #J-18808-Ljbffr

A prominent pharmaceutical company is seeking a Translational PET Imaging Scientist to lead clinical implementation of novel PET tracers in oncology studies. Responsibilities include developing imaging strategies, overseeing studies, and managing regulatory submissions. The ideal candidate should hold a Ph.D. and have extensive experience in advancing PET tracers into clinical trials with proven project leadership. This role offers a hybrid work model and a competitive salary range. #J-18808-Ljbffr

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research. The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research. This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering. Responsibilities: Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions. Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements. Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies. Publish and present research in peer-reviewed journals and at scientific or industry conferences. Contribute to strategic planning and innovation in wind engineering research initiatives. PhD degree. Mechanical, Civil, Aerospace Engineering or related fields. Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent). Proficient in programming languages such as C++, Python, R, MATLAB. Skilled in high-performance computing (HPC) and parallel computing environments. Experience with wind tunnel testing or field measurements is highly desirable. Familiarity with relevant building codes and standards is a plus. Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.