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Sr. Applied Scientist, Amazon Ads
Amazon 4.7
Senior principal scientist job in Santa Monica, CA
Application deadline: Applications will be accepted on an ongoing basis
Amazon Ads is re-imagining advertising through cutting-edge generative artificial intelligence (AI) technologies. We combine human creativity with AI to transform every aspect of the advertising life cycle-from ad creation and optimization to performance analysis and customer insights. Our solutions help advertisers grow their brands while enabling millions of customers to discover and purchase products through delightful experiences. We deliver billions of ad impressions and millions of clicks daily, breaking fresh ground in product and technical innovations. If you're energized by solving complex challenges and pushing the boundaries of what's possible with AI, join us in shaping the future of advertising.
Why you'll love this role:
This role offers unprecedented breadth in ML applications and access to extensive computational resources and rich datasets that will enable you to build truly innovative solutions. You'll work on projects that span the full advertising life cycle, from sophisticated ranking algorithms and real-time bidding systems to creative optimization and measurement solutions.
You'll work alongside talented engineers, scientists, and product leaders in a culture that encourages innovation, experimentation, and bias for action, and you'll directly influence business strategy through your scientific expertise. What makes this role unique is the combination of scientific rigor with real-world impact. You'll re-imagine advertising through the lens of advanced ML while solving problems that balance the needs of advertisers, customers, and Amazon's business objectives.
Your impact and career growth:
Amazon Ads is investing heavily in AI and ML capabilities, creating opportunities for scientists to innovate and make their marks. Your work will directly impact millions. Whether you see yourself growing as an individual contributor or moving into people management, there are clear paths for career progression. This role combines scientific leadership, organizational ability, technical strength, and business understanding. You'll have opportunities to lead technical initiatives, mentor other scientists, and collaborate with senior leadership to shape the future of advertising technology. Most importantly, you'll be part of a community that values scientific excellence and encourages you to push the boundaries of what's possible with AI.
Watch two Applied Scientists at Amazon Ads talk about their work:
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Learn more about Amazon Ads:
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Key job responsibilities
As a Senior Applied Scientist in Amazon Ads, you will:
- Research and implement cutting-edge ML approaches, including applications of generative AI and large language models
- Develop and deploy innovative ML solutions spanning multiple disciplines - from ranking and personalization to natural language processing, computer vision, recommender systems, and large language models
- Drive end-to-end projects that tackle ambiguous problems at massive scale, often working with petabytes of data
- Build and optimize models that balance multiple stakeholder needs - helping customers discover relevant products while enabling advertisers to achieve their goals efficiently
- Build ML models, perform proof-of-concept, experiment, optimize, and deploy your models into production, working closely with cross-functional teams including engineers, product managers, and other scientists
- Design and run A/B experiments to validate hypotheses, gather insights from large-scale data analysis, and measure business impact
- Develop scalable, efficient processes for model development, validation, and deployment that optimize traffic monetization while maintaining customer experience
Basic Qualifications
- 5+ years of building machine learning models for business application experience
- PhD, or Master's degree and 6+ years of applied research experience
- Experience programming in Java, C++, Python or related language
- Experience with neural deep learning methods and machine learning
Preferred Qualifications
- Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc.
- Experience with large scale distributed systems such as Hadoop, Spark etc.
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner.
Our compensation reflects the cost of labor across several US geographic markets. The Colorado base pay for this position ranges from $167,100/year up to $226,100/year. The National base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************* . This position will remain posted until filled. Applicants should apply via our internal or external career site.
$150.4k-260k yearly 4d ago
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Associate Principal Data Scientist
Activision Blizzard, Inc. 4.6
Senior principal scientist job in Santa Monica, CA
Job Title:Associate Principal Data ScientistRequisition ID:R025545Job Description:Your Role Within Our KingdomWe are seeking an Associate Principal Data Scientist-a highly experienced and technically deep individual contributor who leads through influence, owns high-impact initiatives, and drives scientific excellence across experimentation and modeling.Responsibilities:
Lead the design and execution of large-scale data science initiatives, shaping the roadmap for experimentation and modeling across teams.
Apply advanced statistical, optimization, and machine learning techniques (e.g., time-series, regression/classification, recommendation engines, reinforcement learning, and gen AI) to drive system understanding and develop data-powered solutions across the organization.
Own design and evaluation of experimentation for optimization systems.
Provide technical direction, mentor senior data scientists, and set high standards for scientific rigor, communication, and reproducibility.
Partner cross-functionally with Product, Engineering, and Game Studios to frame ambiguous problems, scope solutions, and influence strategy.
Champion innovation by evaluating new methodologies and tools, and by raising the bar for scalable, interpretable, and actionable data science.
Skills to Create ThrillsMinimum Qualifications:
Master's degree or PhD in a quantitative field (e.g., Statistics, Mathematics, Computer Science, Economics, Engineering, Operations Research).
14+ years of industry experience (or equivalent post-graduate experience) in data science, experimentation, statistical modeling, and machine learning, including work with large-scale systems.
Proficient in Python and SQL; familiarity with big data tools (e.g., Spark, Hive) and cloud computing platforms (e.g., GCP, AWS).
Strong systems thinking-able to zoom out and define strategy while also diving deep into code and analysis.
Excellent communication and collaboration skills, with demonstrated experience partnering across Product, Engineering and Businessteams.
Demonstrated experience mentoring, influencing, and elevating the technical bar across a data science organization.
Bonus Points
Experience working with advertising data products or monetization systems.
Prior work with mobile gaming studios or player behavior modeling.
Experience in developing or maintaining experimentation platforms.
Familiarity with modern data orchestration and versioning (e.g., Airflow, dbt, MLflow).
We love hearing from anyone who is enthusiastic about changing the games industry. Not sure you meet all qualifications? Let us decide! Research shows that women, veterans, and members of other under-represented groups tend to not apply to jobs when they think they may not meet every qualification, when, in fact, they often do! We are committed to creating a diverse and inclusive environment and strongly encourage you to apply.We are committed to working with and providing reasonable assistance to individuals with physical and mental disabilities. If you are a disabled individual requiring an accommodation to apply for an open position, please email your request to accommodationrequests@activisionblizzard.com. General employment questions cannot be accepted or processed here. Thank you for your interest.We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, gender identity, age, marital status, veteran status, or disability status, among other characteristics.
Rewards
We provide a suite of benefits that promote physical, emotional and financial well-being for ‘Every World' - we've got our employees covered! Subject to eligibility requirements, the Company offers comprehensive benefits including:
Medical, dental, vision, health savings account or health reimbursement account, healthcare spending accounts, dependent care spending accounts, life and AD&D insurance, disability insurance;
401(k) with Company match, tuition reimbursement, charitable donation matching;
Paid holidays and vacation, paid sick time, floating holidays, compassion and bereavement leaves, parental leave;
Mental health & wellbeing programs, fitness programs, free and discounted games, and a variety of other voluntary benefit programs like supplemental life & disability, legal service, ID protection, rental insurance, and others;
If the Company requires that you move geographic locations for the job, then you may also be eligible for relocation assistance.
Eligibility to participate in these benefits may vary for part time and temporary full-time employees and interns with the Company. You can learn more by visiting ***************************************
In the U.S., the standard base pay range for this role is $143,060.00 - $264,846.00 Annual. These values reflect the expected base pay range of new hires across all U.S. locations. Ultimately, your specific range and offer will be based on several factors, including relevant experience, performance, and work location. Your Talent Professional can share this role's range details for your local geography during the hiring process. In addition to a competitive base pay, employees in this role may be eligible for incentive compensation. Incentive compensation is not guaranteed. While we strive to provide competitive offers to successful candidates, new hire compensation is negotiable. #J-18808-Ljbffr
$143.1k-264.8k yearly 2d ago
Associate Scientist
ACL Digital
Senior principal scientist job in Santa Monica, CA
• Extraction and preparation of DNA and RNA from various sources
• Preparation of DNA, RNA, and ATAC-seq libraries from bulk and/or single cells for NGS sequencing
• Perform quality control on samples and libraries.
• Troubleshoot the experimental procedures and protocols for library preparation and sequencing under supervision
• Perform Next Generation Sequencing experiments on Illumina platforms and other platforms
• Perform qPCR for library quality control
• Maintain updated working knowledge of Genomics technologies and develop significant experience in next-generation sequencing applications
• Keep records of experiments in electronic notebook (ELN)
• Deliver scientific findings effectively in group meetings and collaborative forums
Basic Qualifications
Master's Degree
OR
Bachelor's Degree and 2+ years of scientific experience
OR
AA Degree and 4+ years of scientific experience
OR
High School Degree and 5+ years of scientific experience
Preferred Qualifications
• Bachelor's degree in Biological Sciences, Molecular Biology, Biochemistry, Bioengineering, Genetics, or related fields
• 2+ years of hands-on experience with Next Generation Sequencing (NGS) platforms, various NGS assays, and their underlying sequencing methodology
• Hands-on experience with DNA and RNA extraction from various sources
• Ability to learn new techniques in a fast-paced environment
• Demonstrated ability to solve scientific and engineering problems
• Excellent organizational skills and efficiency at getting tasks done
• Goal oriented and looking to take on additional responsibilities
• Experience working in a multi-disciplinary environment
• Experience working with LIMS and electronic notebook e.g. Benchling
• Excellent interpersonal, verbal, and written communication skills
• An excellent work ethic, ability to work in a dynamic environment, and ability to adapt to changing priorities
$81k-132k yearly est. 5d ago
Lead Target Discovery Scientist - In Vitro Biology
Amgen Sa 4.8
Senior principal scientist job in Thousand Oaks, CA
A leading biotech company in Thousand Oaks seeks a SeniorPrincipalScientist to lead a team focused on in vitro modeling for target discovery. This role involves collaboration across therapeutic areas and implementing innovative technologies. Candidates should have a doctorate and extensive experience in a related field. Competitive compensation, flexible work models, and a comprehensive benefits package are offered.
#J-18808-Ljbffr
$125k-173k yearly est. 4d ago
Postdoctoral Scientist - Microbiology - Jorth Lab
Cedars-Sinai 4.8
Senior principal scientist job in Los Angeles, CA
The Jorth Lab studies host-pathogen interactions of antibiotic-resistant bacteria. We are looking to add a postdoctoral fellow to investigate molecular mechanisms of antibiotic resistance and bacterial pathogenesis, as well as potential therapeutic targets for these hard-to-treat infections. Experience with bacterial genetics, infection models, and computational biology are desirable. The Postdoctoral Scientist will be expected to work independently but in close cooperation and in consultation with the Principal Investigator. The Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. The Postdoctoral Scientist will design and conduct experiments, analyzes and interpret data, and participate in writing publications and giving presentations as author or co-author. May assist in preparation of grant proposals. Not responsible for generating grant funds.
Primary Duties and Responsibilities
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
May participate in publications and presentations as author or co-author
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator
May develop, adapt, and implement new research techniques and protocols.
Analyzes interpret, summarizes, and compiles data.
Performs routine and complex laboratory procedures throughout the training period.
Operates and maintains equipment and instruments.
May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.
Qualifications
Education:
Doctorate Degree in area directly related to field of research specialization is required.
Experience and Skills:
Works independently on research projects designed by a mentor (typically the PI) within area of specialization.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment
Req ID : 12690
Working Title : Postdoctoral Scientist - Microbiology - Jorth Lab
Department : Academic Pathology
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Postdoctoral Scholar
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $62,400 - $93,600
$62.4k-93.6k yearly 2d ago
Principal Applied Scientist
Viant Technology 4.3
Senior principal scientist job in Los Angeles, CA
WHAT YOU'LL DO
Viant's Machine Learning team is at the forefront of transforming the Ad Tech industry through cutting-edge machine learning and AI-driven automation. By eliminating manual processes in digital ad creation, optimization, and measurement, we build autonomous, scalable systems that process hundreds of millions of events daily. We are seeking an exceptional Principal Applied Scientist to drive groundbreaking innovation in applied machine learning. In this role, you will lead end-to-end AI strategy, shape the applied science roadmap, and develop next-generation models in NLP, deep learning, and large-scale AI systems. Your expertise will push the boundaries of AI capabilities, delivering measurable business impact while fostering a research-driven, data-centric culture at Viant. THE DAY-TO-DAY
Lead and Define AI Strategy - Set the vision for applied ML research and AI-driven decision-making across Viant's products and services.
Drive High-Impact Research - Conduct advanced research in NLP, RL, LLMs, and deep learning, publishing in top-tier conferences while applying findings to real-world production systems.
Architect and Deploy ML at Scale - Develop, optimize, and deploy high-throughput, low-latency ML models, collaborating with engineers to bring solutions into production.
Innovate in Generative AI & Causal ML - Explore novel AI techniques, such as LLMs, reinforcement learning, and causal inference, to enhance targeting, personalization, and attribution models.
Experimentation and Validation - Design, run, and analyze A/B experiments to test ML-driven strategies, ensuring data-driven decision-making.
Mentor and Influence - Provide technical leadership for a team of applied scientists and ML engineers, fostering a culture of innovation and excellence.
MUST HAVE
Experience: 7+ years of experience building and deploying machine learning models at scale.
Technical Leadership: Demonstrated ability to lead complex, high-ambiguity ML projects from research to production.
Academic & Industry Recognition: Masters + At least two peer-reviewed publications in deep learning, NLP, or a related AI domain or a PhD in Computer Science, Machine Learning, Statistics, or a related quantitative field.
Deep Expertise in ML & AI: Strong foundation in deep learning, NLP, generative AI, and causal inference.
Programming & Frameworks: Proficiency in Python and deep learning frameworks (TensorFlow, PyTorch, LangChain, Llama Index).
Scalability & Cloud: Experience with distributed computing, cloud ML platforms (AWS, GCP, or Azure), and real-time AI inference.
GREAT TO HAVE
Industry Impact: Publications at top-tier ML/NLP conferences (NeurIPS, ICML, ICLR, ACL, EMNLP, NAACL, AAAI).
Ad Tech Expertise: Experience in digital advertising, real-time bidding, or audience modeling.
Generative AI Applications: Hands-on experience with LLMs and multimodal AI applications.
Optimization & Personalization: Strong background in reinforcement learning, dynamic pricing, or recommendation systems.
LIFE AT VIANT
Investing in our employee's professional growth is important to us, but so is investing in their well-being. That's why Viant was voted one of the best places to work and some of our favorite employee benefits include fully paid health insurance, paid parental leave and unlimited PTO and more.
Base compensation range: $220,000 - $260,000 In accordance with California law, the range provided is Viant's reasonable estimate of the compensation for this role. Final title and compensation for the position will be based on several factors including work experience and education.
#LI-KW1
About Viant
Viant Technology Inc. (NASDAQ: DSP) is a leader in CTV and AI-powered programmatic advertising, dedicated to driving innovation in digital marketing. Viant's omnichannel platform built for CTV allows marketers to plan, execute and measure their campaigns with unmatched precision and efficiency. With the launch of ViantAI, Viant is building the future of fully autonomous advertising solutions, empowering advertisers to achieve their boldest goals. Viant was recently awarded Best AI-Powered Advertising Solution and Best Demand-Side Platform by MarTech Breakthrough, Great Place to Work certification and received the Business Intelligence Group's AI Excellence Award. Learn more at viantinc.com.
Viant is an equal opportunity employer and makes employment decisions on the basis of merit. Viant prohibits unlawful discrimination against employees or applicants based on race (including traits historically associated with race, such as hair texture and protective hairstyles), religion, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, reproductive health decision making, gender, gender identity, gender expression, age, military status, veteran status, uniformed service member status, sexual orientation, transgender identity, citizenship status, pregnancy, or any other consideration made unlawful by federal, state, or local laws. Viant also prohibits unlawful discrimination based on the perception that anyone has any of those characteristics, or is associated with a person who has or is perceived as having any of those characteristics. By clicking “Apply for this Job” and providing any information, I accept the Viant California Personnel Privacy Notice.
$220k-260k yearly Auto-Apply 60d+ ago
Senior Applied AI Scientist
Cisco 4.8
Senior principal scientist job in Santa Monica, CA
**Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment.
**Your Impact**
+ Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events.
+ Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale.
+ Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact.
+ Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes.
+ Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans.
**Minimum Qualifications:**
+ PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience.
+ Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling.
+ Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow)
+ Experience translating research ideas into production systems.
**Preferred Qualifications:**
+ Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models.
+ Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data.
+ Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights.
+ Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty.
+ Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy.
+ MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models.
+ Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications.
**Why Cisco?**
At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint.
Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere.
We are Cisco, and our power starts with you.
**Message to applicants applying to work in the U.S. and/or Canada:**
The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits.
Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process.
U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time.
U.S. employees are eligible for paid time away as described below, subject to Cisco's policies:
+ 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees
+ 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco
+ Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees
+ Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations)
+ 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next
+ Additional paid time away may be requested to deal with critical or emergency issues for family members
+ Optional 10 paid days per full calendar year to volunteer
For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies.
Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows:
+ .75% of incentive target for each 1% of revenue attainment up to 50% of quota;
+ 1.5% of incentive target for each 1% of attainment between 50% and 75%;
+ 1% of incentive target for each 1% of attainment between 75% and 100%; and
+ Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation.
For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid.
The applicable full salary ranges for this position, by specific state, are listed below:
New York City Metro Area:
$199,700.00 - $292,800.00
Non-Metro New York state & Washington state:
$174,500.00 - $260,500.00
* For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined.
** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.
Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis.
Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.
$199.7k-292.8k yearly 55d ago
Senior Research Scientist, Generative AI
Snap 4.7
Senior principal scientist job in Los Angeles, CA
Snap Inc is a technology company. We believe the camera presents the greatest opportunity to improve the way people live and communicate. Snap contributes to human progress by empowering people to express themselves, live in the moment, learn about the world, and have fun together. The Company's three core products are Snapchat, a visual messaging app that enhances your relationships with friends, family, and the world; Lens Studio, an augmented reality platform that powers AR across Snapchat and other services; and its AR glasses, Spectacles.
Snap Research serves as an innovation engine for the company. Our projects range from solutions to hard technical problems that significantly enhance Snap's existing products, to riskier explorations that can lead to fundamental paradigm shifts in the way people communicate and express themselves. The team consists of scientists and engineers who experiment with and invent new technology that has a lasting impact on Snap's products.
We are looking for a Research Scientist to join the Creative Vision Research Team! At Creative Vision, we focus on making everyone into a creator. We believe creativity is achieved when technology understands the world, humans and objects, provides a range of creative generation and manipulation tools and efficient real-time experiences. Our technology impacts and contributes to multiple products at Snap.
What you'll do:
Define, lead and execute a multi-year research agenda
Architect and implement large-scale multimodal generative projects
Share your expertise with other teammates and interns
Publish your work to top conferences
Partner with engineering teams to deliver your technology to millions of Snapchatters
Knowledge, Skills, & Abilities:
Strong technical knowledge of statistics, machine learning, vision and state-of-the-art deep learning literature
Proven record of defining, leading and executing challenging research projects
Strong computer science fundamentals, problem solving skills, programming (Python, C, C++)
Proven ability to lead interns, PhD students, junior researchers or ML engineers
Minimum Qualifications:
PhD in a related technical field such as computer science, statistics, mathematics, machine learning or equivalent years of experience
2+ years of industry or postdoc experience with large scale generative AI, building foundational models, and large model training in academia or industry
Experience with large scale, distributed training across hundreds of machines and cloud computing
Experience with large-scale data collection and annotation best practices
Track record of publications in top-tier international research venues (e.g. ICLR, AAAI, NeurIPS, CVPR, ECCV, ICCV, SIGGRAPH)
Preferred Qualifications:
Experience with multimodal machine learning, involving images, videos, audio, text, speech
Experience with 3D computer vision, non-rigid and articulated 3D registration and synthesis
Experience with efficient Gen AI techniques, such as quantization, pruning, distillation, efficient training for generation and understanding, parameter- and data-efficient learning, and efficient VLMs
Experience with low level vision techniques, such as image and video quality assessment, compression, restoration, and super-resolution
Experience with 3D Articulated human motion generation
Experience with CUDA framework and low level optimization of generative pipelines for training and inference
Strong theoretical background in generative modeling and diffusion models
If you have a disability or special need that requires accommodation, please don't be shy and provide us some information.
"Default Together" Policy at Snap: At Snap Inc. we believe that being together in person helps us build our culture faster, reinforce our values, and serve our community, customers and partners better through dynamic collaboration. To reflect this, we practice a “default together” approach and expect our team members to work in an office 4+ days per week.
At Snap, we believe that having a team of diverse backgrounds and voices working together will enable us to create innovative products that improve the way people live and communicate. Snap is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws. EOE, including disability/vets.
We are an Equal Opportunity Employer and will consider qualified applicants with criminal histories in a manner consistent with applicable law (by example, the requirements of the San Francisco Fair Chance Ordinance and the Los Angeles Fair Chance Initiative for Hiring, where applicable).
Our Benefits: Snap Inc. is its own community, so we've got your back! We do our best to make sure you and your loved ones have everything you need to be happy and healthy, on your own terms. Our benefits are built around your needs and include paid parental leave, comprehensive medical coverage, emotional and mental health support programs, and compensation packages that let you share in Snap's long-term success!
Compensation
In the United States, work locations are assigned a pay zone which determines the salary range for the position. The successful candidate's starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. The starting pay may be negotiable within the salary range for the position. These pay zones may be modified in the future.
Zone A (CA, WA, NYC):
The base salary range for this position is $209,000-$313,000 annually.
Zone B:
The base salary range for this position is $199,000-$297,000 annually.
Zone C:
The base salary range for this position is $178,000-$266,000 annually.
This position is eligible for equity in the form of RSUs.
$209k-313k yearly Auto-Apply 33d ago
Principal Research Scientist, Drug Discovery
Acurastem 3.3
Senior principal scientist job in Los Angeles, CA
AcuraStem is a pre-clinical stage company focused on amyotrophic lateral sclerosis (ALS). AcuraStem is advancing novel therapeutic approaches for ALS using patient-derived stem cell models. The incumbent candidate should have experience in neurobiology, stem cells, familiarity with CNS animal models and the pharmaceutical process of drug discovery.
Job Description
The principalscientist is expected to work independently but in close cooperation and in consultation with the AcuraStem leadership and other scientists. The principalscientist is responsible for development and execution of bioassays, and pharmacology of AcuraStem's ALS program. This position will play a key role in AcuraStem's therapeutic discovery and development process. The efforts will include including working with key opinion leaders to advance disease-related target engagement and efficacy investigations, ultimately driving to clinical candidate and indication selection.
The principalscientist will be expected to assist in the preparation/submission of multiple grant proposals and also prepare full manuscripts for publication based on their research results. The principalscientist will be expected to maintain establish and maintain institutional IRB/SCRO protocols as well as develop new animal and IACUC protocols.
We are seeking a team player who is persistent, and tenacious with an objective to complete experimental plans with high quality, on time and on budget. The ideal candidate should be extremely well organized in order to document and communicate experimental results clearly and concisely. The candidate will be expected to provide regular updates, documentation, and communication of project results to senior leadership.
The successful candidate will be responsible for performing cell maintenance, expansion and genetic modification of cell models (including stem cells) using viral vectors or other gene-editing methods. A proven record with stem cell culture techniques is important. Prior experience in using pluripotent stem cells is a plus.
RESPONSIBILITIES:
Advance the AcuraStem laboratory infrastructure for target identification, assay development, pharmacology and lead optimization of AcuraStems lead ALS program.
Develop strategy for implementing translational research approaches that interface collaboratively with contract research organizations (Preclinical Development, Chemistry and Clinical teams). These efforts would include in vivo PK/PD studies, design and synthesis of compounds, and development of clinically translatable biomarkers.
Provide day-to-day scientific, technical and organizational leadership within the research team, advancing IP considerations to ensure optimal long-term patent protection around compounds as well as novel technologies.
In collaboration with the team, create assays and qualification workflows for drug discovery programs, including routine compound testing of specificity, potency, and pharmaceutics with operational excellence.
Possess keen strategic and technical expertise with experience working in a highly-matrixed organization interfacing with external partners and company founders. Mentor and lead 2-5 staff internally. Oversee coordination of CROs to ensure timeliness and progression of projects is in line with project plans. Balance workflow and department resourcing on platform expansion versus product focus in real-time based on strategic direction and priorities set by company management.
Develop a culture of accountability, transparency, results, innovation and collegiality within the research organization by establishing performance expectations and hiring and developing top talent to achieve organizational delivery goals. Through the leadership of others, ensure employees are appropriately trained, following corporate policies, SOPs and practices without compromising quality.
Present results at scientific meetings and in publications of peer-reviewed scientific journals. Review technical publications, articles and abstracts to stay current of drug research developments.
Travel as needed to establish and manage key external drug discovery partnerships and technology expansion relationships at CROs and partner labs.
Qualifications
PhD, with expertise in neurobiology, preferably translational biology, and a minimum of 8 years' industry experience post Ph.D.
Demonstrated leadership or key involvement in drug discovery and development processes
Demonstrated success delivering therapeutic candidates into development
Expertise in multiple neuroscience areas. ALS experience also strongly preferred.
Demonstrated project team leadership in a matrixed environment; small company and/or start-up experience preferred
Additional Information
The candidate must already be in the USA and approved to work immediately.
$135k-199k yearly est. 20h ago
Senior Research Scientist, Quantum Error Correction
Q-Ctrl
Senior principal scientist job in Los Angeles, CA
About the team The Quantum Computing Research team is dedicated to developing innovative methods to get the best possible performance from contemporary and next generation quantum computers. We push toward quantum advantage by developing cutting-edge applications, employing AI, control theory, and physics principles to optimize and automate critical parts of the quantum computing stack. We conduct pioneering research looking toward the near future, including quantum error correction and the integration of quantum computers with high performance computing and data centers.
About the role This amazing role centers around quantum error correction (QEC) research. You'll collaborate closely across research and engineering teams to produce high impact research and publication and to translate scientific advances into high-impact software solutions. This is your opportunity to work at the forefront of quantum computing, driving real-world innovation in a rapidly evolving field.
As a Research Scientist, you'll be responsible for developing solutions for quantum technologies and deploying them in the Q-CTRL product suite.What you'll be doing:
Design and implement efficient and reliable methods to solve key challenges facing real quantum computers.
Stay up to date with advances in quantum computing and QEC research, applying this knowledge to develop cutting-edge methodologies.
Performing innovative research on aspects of QEC, such as, but not limited to; designing and optimizing decoders, developing compilation schemes and computation architectures for FTQC, optimizing logical operation schemes, using QEC primitives to boost near term applications
Utilize methods from a range of fields, including control theory, optimization, machine learning, computer science, and data analysis.
Publishing high-impact papers and presenting at top conferences
Collaborate with engineering teams to translate your ideas into production-quality software.
Explain and present your work in clear and accessible language. Incorporate feedback and foster effective collaboration with colleagues.
Use open-source scientific computing packages like Qiskit, NumPy, Networkx, Scipy, Scikit-learn, and PyTorch to build high-quality research code to develop, demonstrate, and test new algorithms and methods.
Other duties within the Employee's skills and experience, or with reasonable training.
Ideally you'll have:
A PhD degree in Physics, Engineering, Mathematics, Computer Science, or a related discipline.
Relevant industry or postdoctoral experience in quantum error correction. PhD graduates with proven track record in QEC research will be considered.
Expertise in top leading QEC codes such as the surface and qLDPC codes.
Expertise in one or more of the following: decoders, compilation, computation architectures.
A track record of conducting impactful research, demonstrated through publications and/or presentations in well-regarded journals and/or conferences.
Experience in developing software for scientific experiments using Python.
It would be fantastic if you have these skills/experience but not essential:
Experience with high-performance languages such as Rust, C++, or Julia.
A strong background in relevant methods from fields such as control theory, optimization, machine learning, or data analysis.
Familiarity with error suppression techniques used in quantum computing, such as dynamical decoupling, readout mitigation, zero-noise extrapolation, Pauli twirling, or pulse-level optimization.
Familiarity with executing circuits in Qiskit.
Exceptional scientific communication skills, evidenced by a track-record of teaching, scientific outreach, writing, and/or speaking in front of both general and expert audiences.
Familiarity with hardware, such as FPGAs or ASICs
A track record of winning contracts or grants
We take a multidisciplinary approach to quantum computing research, bringing together experts from diverse fields. We particularly value versatile and self-motivated problem solvers. If you are passionate about making quantum computers useful, we strongly encourage you to apply, even if you do not meet all of the requirements listed above.
SalaryThe base salary for this position is targeted between $140K - $192K and will ultimately be determined by specific job-related skills, experience, level, location and other contributing factors. Depending on the position offered, this role may be eligible for annual discretionary bonuses, equity and other forms of compensation outside of the targeted range. For more information on benefits at Q-CTRL, please visit our careers page at ***************************
Should you have any questions related to the compensation package, please speak directly with the Talent Acquisition representative.
About Q-CTRLQ-CTRL is the global leader in AI-powered quantum control infrastructure software. We build the tools that make quantum technology useful, solving the hardest challenges in quantum computing and quantum sensing to deliver real-world impact.
Founded in 2017, we operate globally with offices in Sydney, Los Angeles, San Francisco, Berlin, and Oxford. Our teams bring together technical and multi-disciplinary expertise across the product lifecycle, and we're hiring talent to help scale every part of the business. We work quickly to turn cutting-edge science into deployable technology.
In 2024 we raised US$113 million in Series B funding, the largest aggregate investment for a quantum software company. Six months later we delivered the first commercial quantum advantage with Ironstone Opal, our field-validated quantum navigation solution for defense and industry.
At Q-CTRL, we prioritize outcomes over hours. We offer flexibility, equity potential, and competitive benefits that reflect our high-performance culture. If you're ready to help shape the future of quantum, we'd love to hear from you!
Qualified applications with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
Please be advised that our communications will only come from *************** domain. All our active job postings are available on our company website.
To recruitment agencies, we do not accept unsolicited branded profiles and are not responsible for any fees related to unsolicited resumes.
$140k-192k yearly Auto-Apply 60d+ ago
Senior Research Scientist, Superconducting Qubits
Q-CTRL
Senior principal scientist job in Los Angeles, CA
About the team The Quantum Computing Research team is dedicated to developing innovative methods to get the best possible performance from contemporary and next generation quantum computers. We push toward quantum advantage by developing cutting-edge applications, employing AI, control theory, and physics principles to optimize and automate critical parts of the quantum computing stack. We conduct pioneering research looking toward the near future, including quantum error correction and the integration of quantum computers with high performance computing and data centers.
About the role
In this role, you will work in a team of quantum scientists to develop software solutions for calibration and optimization of superconducting quantum hardware. You will focus on building robust routines for tuning up high-fidelity two-qubit gates, optimizing the full processor at scale, and maintaining peak performance in real time. You will collaborate regularly with other cross-functional teams such as research, product and engineering, to apply your insights to a variety of quantum computing challenges and turn your ideas into usable software tools. This position offers the opportunity to work at the forefront of quantum computing, driving innovation, and delivering impactful solutions.
What you'll be doing:
* Perform cryogenic measurements and characterization of superconducting qubits.
* Invent, implement and test novel control protocols for tuning and optimizing two-qubit gates.
* Develop scalable protocols for processor-wide optimization (e.g. cross-talk mitigation, leakage reduction, defects mitigation), and real-time retuning.
* Collaborate with your colleagues in the engineering and product teams to translate ideas and research outcomes into production-level software.
* Explain, document and present research solutions in accessible language.
Ideally you'll have:
* An advanced degree in Physics, Engineering, or a closely related discipline. A PhD is preferred, but we also consider exceptional candidates with previous industry experience.
* 2 years of experience conducting research in a relevant field.
* Previous experience in tune-up and characterization of superconducting qubits.
* Expertise in numerical techniques, statistical learning, and optimization algorithms.
* A good grasp of software development best practices, and experience in developing software modules for qubit measurement and control (Python, C++, Rust).
We take a multidisciplinary approach to quantum computing research, bringing together experts from diverse fields. We particularly value versatile and self-motivated problem solvers. If you are passionate about making quantum computers useful, we strongly encourage you to apply, even if you do not meet all of the requirements listed above.
Salary
The base salary for this position is targeted between $140K - $192K and will ultimately be determined by specific job-related skills, experience, level, location and other contributing factors. Depending on the position offered, this role may be eligible for annual discretionary bonuses, equity and other forms of compensation outside of the targeted range. For more information on benefits at Q-CTRL, please visit our careers page at ***************************
Should you have any questions related to the compensation package, please speak directly with the Talent Acquisition representative.
About Q-CTRL
Q-CTRL is the global leader in AI-powered quantum control infrastructure software. We build the tools that make quantum technology useful, solving the hardest challenges in quantum computing and quantum sensing to deliver real-world impact.
Founded in 2017, we operate globally with offices in Sydney, Los Angeles, San Francisco, Berlin, and Oxford. Our teams bring together technical and multi-disciplinary expertise across the product lifecycle, and we're hiring talent to help scale every part of the business. We work quickly to turn cutting-edge science into deployable technology.
In 2024 we raised US$113 million in Series B funding, the largest aggregate investment for a quantum software company. Six months later we delivered the first commercial quantum advantage with Ironstone Opal, our field-validated quantum navigation solution for defense and industry.
At Q-CTRL, we prioritize outcomes over hours. We offer flexibility, equity potential, and competitive benefits that reflect our high-performance culture. If you're ready to help shape the future of quantum, we'd love to hear from you!
Qualified applications with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
Please be advised that our communications will only come from *************** domain. All our active job postings are available on our company website.
To recruitment agencies, we do not accept unsolicited branded profiles and are not responsible for any fees related to unsolicited resumes.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
$140k-192k yearly Easy Apply 44d ago
Sr research scientist (EU)
Barrington James
Senior principal scientist job in Los Angeles, CA
Senior Research Scientist - Real-World Evidence & Evidence Synthesis
Employment Type: Full-time | Permanent
We are hiring a Senior Research Scientist to join a consultancy's Real-World Evidence (RWE) team. This is a remote, hands-on role focused on delivering high-quality evidence synthesis projects, with a strong emphasis on indirect treatment comparisons (ITCs). The role involves technical delivery, client interaction, and mentoring of junior team members.
Key Responsibilities
Lead delivery of evidence synthesis projects (SLRs, NMA, MAIC, STC)
Develop protocols, analysis plans, reports, and client-ready presentations
Manage client communication and lead study discussions
Mentor junior researchers and support internal knowledge sharing
Contribute to project planning, timelines, and proposal development
Requirements
Essential:
5+ years' experience in HEOR, RWE, or evidence synthesis
Proven expertise in ITCs (NMA, MAIC, STC)
Experience in a consultancy or service provider
Involvement in HTA submissions (e.g. NICE or EU equivalents)
Strong communication and delivery skills
Desirable:
Experience mentoring junior staff
Proficiency in R, WinBUGS, or related tools
Broad therapeutic area experience
Additional Information
Remote role (EU-based candidates preferred)
Competitive salary and benefits
Collaborative, delivery-focused environment
Start date from August or September 2025
If you or someone you know are interested, click apply!
$110k-177k yearly est. 60d+ ago
Scientist/Sr. Scientist: Tumor Immunology
Nammi Therapeutics
Senior principal scientist job in Los Angeles, CA
As the founding Biologist at Nammi, you have the opportunity to help establish the department and its capabilities in this exciting and growing company. The role will be responsible for evaluating anti-tumor and immunotherapies in in vitro assays to determine mechanism of action, potency, and selectivity, while designing and managing in vivo studies to be done at external CROs. Translational biology including assay design for PD markers in the animal and clinical studies will also be an important component as well as contributing to IND and patent writing for the developing products.
Job Responsibilities
· Establish internal molecular and cell biology infrastructure and capabilities
· Design and management of in vivo studies at external CROs
· Characterization of efficacy and mechanism of action of ImmunoOncology therapeutic candidates
· Interface with the Chemistry department to efficiently evaluate and select lead candidates for the development pipeline
· Recruit and manage research associates to implement the evaluation of therapeutic candidates
· Create and maintain a safe, innovative, and positive environment for the Biology Department
· Presentation of products and technology internally and externally for scientific, investor, and partnering audiences.
Job Qualifications
Required:
· Ph.D in Molecular Biology, Cancer Biology, Cell Biology, or equivalent plus >5 years post-graduate work experience
· Experience working in industry as a Cancer Biologist
· Experience managing research associates
Preferred:
· Experience in Tumor Immunotherapy
· Industrial experience in Drug Discovery/development
$110k-177k yearly est. 60d+ ago
Senior Scientist, DMPK
Ellison Medical Institute
Senior principal scientist job in Los Angeles, CA
Job Title: SeniorScientist, DMPK Annual Base Salary: DOE, $140,000-$185,000 along with bonus eligibility and a comprehensive benefits package Our Mission The Ellison Medical Institute, formerly known as the Ellison Institute of Technology Los Angeles, strives to spark innovation, leverage technology, and drive interdisciplinary, patient-centered research to continually enhance health, reimagine and redefine cancer care, and transform lives.
Established in 2016 as a medical research and development center, the Institute features innovation labs for artificial intelligence and molecular analytics and was among the first organizations to vertically integrate the interdisciplinary study and treatment of disease. We offer multifaceted programs, including a preventative medicine and cancer clinic, cross-disciplinary research laboratories, a health policy think-tank, and community outreach and educational programs.
Please visit emila.org for more details.
Job Summary
The Ellison Medical Institute is seeking an accomplished and passionate SeniorScientist in Drug Metabolism and Pharmacokinetics (DMPK) to join our Translational Biology team. In this high-impact role, you will apply your expertise in pharmacokinetics (PK), toxicology (TOX), and drug metabolism (ADME) to accelerate the advancement of groundbreaking new molecular entities as our lead compound advances into IND-enabling and first-in-human studies. This is a pivotal role in shaping the nonclinical strategy, managing CRO partnerships, and authoring the IND nonclinical modules to support regulatory filings and clinical transition. The ideal candidate thrives in a dynamic start-up environment and can balance hands-on scientific work with strategic oversight.
This is a unique opportunity to be at the forefront of early-stage drug development, in a collaborative, multidisciplinary environment, where your contributions will help shape the future of medicine.
Why You Should Join Us:
Drive Innovation: Contribute to the advancement of cutting-edge drug development and therapeutic strategies that transform patient care.
Be at the Forefront: Work with a world-class team and integrate new technologies in PK/TOX and ADME studies to accelerate the drug discovery pipeline.
Make an Impact: Help shape clinical trial strategies and regulatory pathways that will support the successful progression of therapeutic candidates into clinical trials.
Job Accountabilities:
Lead PK/TOX and ADME Studies
Design, execute, and interpret ADME, PK, and toxicology studies (in vitro and in vivo) to characterize compound properties and support IND submission.
Develop study designs aligned with FDA/EMA guidance for IND-enabling packages, including dose range finding and GLP toxicology studies.
Integrate PK/TOX findings into overall development strategy and advise on risk assessment for first-in-human studies.
Data Analysis and Modeling
Perform or direct PK and ADME data analysis using Phoenix WinNonlin or equivalent modeling software.
Conduct human PK predictions and first-in-human dose projections to inform clinical study design.
Synthesize and communicate results in cross-functional meetings to guide decision-making and clinical translation.
CRO Management and Oversight
Identify, qualify, and manage CROs for ADME, PK, and toxicology studies, ensuring high-quality data delivery and adherence to GLP standards.
Provide clear technical direction, review study protocols, monitor study progress, and critically assess data deliverables.
Establish timelines, budgets, and deliverables for external studies and ensure alignment with regulatory milestones.
Regulatory and IND Authoring
Lead the preparation and authorship of nonclinical sections (Module 2.6, 2.7.1, and 4.2) of the IND, collaborating with internal teams and external consultants as needed.
Support responses to regulatory agency questions and contribute to the nonclinical components of investigator brochures and clinical protocols.
Ensure that all documentation and data are audit-ready and compliant with ICH and FDA standards.
Cross-Functional Collaboration
Partner with clinical, CMC, and research teams to ensure preclinical findings are effectively translated into clinical development.
Provide DMPK guidance for formulation selection, route of administration, and clinical study design.
Contribute to strategic discussions on candidate selection, dose justification, and safety margins.
Innovation and Technology Integration
Introduce and implement innovative modeling, bioanalytical, and in silico tools to enhance predictive accuracy and program efficiency.
Stay current with emerging regulatory expectations, technologies, and best practices in DMPK and toxicology.
ADDITIONAL INFORMATION
Required Education & Experience:
PhD in Pharmacokinetics, Toxicology, Drug Metabolism, Pharmaceutical Sciences, Pharmacology, or a related field, with 5+ years of relevant industry experience.
Proven track record of designing and interpreting PK/TOX and ADME studies to support drug discovery and development.
Strong understanding of GLP regulations, ICH M3 (R2), and FDA nonclinical study expectations.
Experience preparing IND nonclinical modules and interacting with regulatory agencies.
Proficiency with PK modeling and simulation tools (e.g., WinNonlin, GastroPlus, Simcyp).
Experience managing CROs conducting PK/TOX studies, ensuring quality, compliance, and alignment with IND-enabling requirements.
Experience working across multiple drug modalities, including small molecules and biologics, is preferred.
For the safety and health of employees, guests, and patients, the Ellison Medical Institute may mandate vaccination requirements for employment. The Ellison Medical Institute's policies are always subject to review and change to ensure they are appropriate under the circumstances.
The Ellison Medical Institute is an equal opportunity employer. We believe that an inclusive, collaborative team environment is just as important to our mission as stethoscopes and microscopes. We strive to always provide employees a supportive atmosphere, so they feel confident taking creative risks toward innovation. The Ellison Medical Institute values emotional intelligence and communication with empathy and respect for others. We seek to build a diverse group of people who are curious, have a deep sense of responsibility, and the grit needed to achieve excellence.
$110k-177k yearly est. Auto-Apply 16d ago
Senior Scientist, Drug Substance Development
Varda Co 3.5
Senior principal scientist job in El Segundo, CA
About Varda
Low Earth orbit is open for business. Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules.
From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.
Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.
Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL (coming soon).
Join Varda, and work to create a bustling in-space ecosystem.
About This Role
Our team is looking for highly motivated and creative candidates who will lead efforts in improving therapeutics with microgravity. This is an opportunity in an exciting area of growth for Varda, the role will shape Varda's culture and will play a significant role in establishing the low earth orbit economy.
Responsibilities
Serve as technical lead for pharmaceutical development projects
The candidate will be responsible for supporting drug substance development including characterization of materials, crystallization screening and early-stage process characterization
Responsibilities include design, planning, and hands-on execution of laboratory studies
Drug substance characterization spans solid-state, physicochemical, and particle analysis
Collaborate with process engineers and analytical development scientists
Basic Qualifications
Ph.D. degree in materials science, chemical engineering, organic chemistry, biochemistry with 3+ years of industry experience or M.S. degree in related field with 6+ years of industry experience
Experienced in drug substance development of small molecules (solvent screen, form screening and selection, stability studies)
Preferred Skills And Experience
Ph.D. degree in materials science, chemical engineering, organic chemistry, biochemistry with 5+ years of industry experience
Experience with cradle-to-crave development from early R&D through commercialization
Demonstrated expertise in small molecule crystallography, including structural determination
Pay Range
Salary Range: $140,000.00 - $180,000.00/per year
This role is on-site in El Segundo, CA
Leveling and base salary is determined by job-related skills, education level, experience level, and job performance
You will be eligible for long-term incentives in the form of stock options and/or long-term cash awards
ITAR Requirements
Varda, like all employers, must ensure that its employees working in the United States are lawfully authorized to work in the U.S. Additionally, our employees are exposed to and have access to certain export-controlled items. At present, some of our technology to which employees have access requires a license to be exported to individuals other than “U.S. Persons” as defined in U.S. export regulations. Because our employees are provided access to export-controlled items, our current policy is to only hire “U.S. persons” who are permitted to have access to our technology without an export license.
“US person” means: U.S. citizen, U.S. lawful permanent resident, or protected individual as defined by 8 U.S.C. 1324b(a)(3) (i.e., individual admitted to the U.S. as a refugee or granted asylum in the U.S.)
Learn more about the ITAR here.
Benefits
Exciting team of professionals at the top of their field working by your side
Equity in a fully funded space startup with potential for significant growth (interns excluded)
401(k) matching (interns excluded)
Unlimited PTO (interns excluded)
Health insurance, including Vision and Dental
Lunch and snacks provided on site every day. Dinners provided twice a week.
Maternity / Paternity leave (interns excluded)
Varda Space Industries is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Candidates and employees are always evaluated based on merit, qualifications, and performance. We will never discriminate on the basis of race, color, gender, national origin, ethnicity, veteran status, disability status, age, sexual orientation, gender identity, martial status, mental or physical disability, or any other legally protected status.
E-Verify Statement
Varda Space Industries, Inc. participates in the U.S. Department of Homeland Security E-Verify program. The E-Verify program is an Internet-based employment eligibility verification system operated by the U.S. Citizenship and Immigration Services. Learn more about the E-Verify program.
E-Verify Notice Right To Work Notice
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$140k-180k yearly Auto-Apply 14d ago
Research Scientist - Controlled 3D Generation
Stability Ai
Senior principal scientist job in Los Angeles, CA
About the Role
We're seeking a Research Scientist passionate about 3D generation, flow matching, and diffusion models. You'll help advance the frontier of controllable 3D content creation-building models that generate consistent, editable, and physically grounded 3D assets and scenes.
What You'll Do
Conduct cutting-edge research on flow-matching, diffusion, and score-based methods for 3D generation and reconstruction.
Design and implement scalable training pipelines for controllable 3D generation (meshes, Gaussians, NeRFs, voxels, implicit fields).
Develop techniques for conditioning and control (text, sketch, pose, camera, physics) and multi-view consistency.
Analyse model behaviour through ablations, visualisations, and quantitative metrics.
Collaborate with cross-disciplinary research, graphics, and infrastructure teams to translate research into production-ready systems.
Publish results at top-tier venues and work with interns.
What You Bring
PhD (or equivalent experience) in Machine Learning, Computer Vision, or Computer Graphics.
Published work on diffusion, flow-matching, or score-based generative models (2D or 3D).
Strong engineering and problem-solving abilities: experience with PyTorch, JAX, or CUDA-level optimisation.
Understanding of 3D representations (meshes, Gaussians, signed-distance fields, volumetric grids, implicit networks).
Solid grasp of geometry processing, multi-view consistency, and differentiable rendering.
Ability to scale experiments efficiently and communicate complex results clearly.
Bonus / Preferred
Experience generating coherent 3D scenes with multiple interacting objects, lighting, and spatial layout.
Familiarity with scene-level control (object placement, camera path, simulation, or text-to-scene composition).
Knowledge of video-to-3D, image-to-scene, or 4D temporal generation.
Background in physically-based rendering, simulation, or world-model architectures.
Track record of impactful publications or open-source releases.
Equal Employment Opportunity:
We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or other legally protected statuses.
$91k-152k yearly est. Auto-Apply 60d+ ago
Applied Scientist III
Capital Group International Inc. 4.4
Senior principal scientist job in Los Angeles, CA
“I can succeed as an Applied Scientist III at Capital Group.”
As an Applied Scientist III, you will play a pivotal role in shaping the future of AI at Capital Group and help to establish the GenAI strategy for the Client Group. Your command of cutting-edge technology and expertise in Deep Neural Networks and Generative AI will be instrumental in bringing our visionary solutions to life, delivering groundbreaking applications that will set new standards across the asset management industry. This includes researching and developing scalable applications using Large Language Models (LLMs) and Agentic AI, such as conversational assistants to retrieve information about mutual fund products or market insights and guide clients through investment decisions.
As an independent researcher, you will provide thought leadership in discussions with product and technical leaders to transform business and product visions into groundbreaking AI applications that would help CG remain leaders in asset management. You have the ability to analyze behavioral data, market news, and economic trends to personalize investment outcomes, and develop AI tools that help sales, marketing, and service teams offer relevant solutions to financial advisors. You will design and review AI solutions with a focus on excellence, scalability, employing best practices for data management, model development, and evaluation to ensure the highest quality outcomes.
You will independently drive AI research and innovation with high conviction, collaborating with other scientists and engineers to develop and publish new industry leading ideas, and mentor a talented team of both junior and senior applied scientists, fostering growth and nurturing the next generation of AI leaders.
“I am the person Capital Group is looking for.”
MS in (PhD preferred) Computer Science, Artificial Intelligence, Machine Learning, or related technical field.
10+ years (post MS)/ 8+ years (post PhD) of relevant work experience, including industry experience or as a Researcher in a lab.
Practical experience with the latest advancements in Large Language Models (LLM) and generative AI technology including RAG, including parameter-efficient fine-tuning, instruction fine-tuning, advanced prompt engineering, and Agentic AI frameworks.
Deep technical knowledge of Machine Learning and Deep Learning architectures, such as Transformers, training methodologies, and optimization techniques.
A strong commitment to staying current with the latest advancements in the field, applying cutting-edge academic research to solve complex business challenges, and successfully bringing innovative solutions into production.
Experience working effectively with software engineering teams.
Experience contributing to research communities- publishing papers/blog articles related to machine learning is a plus.
Southern California Base Salary Range: $201,203-$342,045
In addition to a highly competitive base salary, per plan guidelines, restrictions and vesting requirements, you also will be eligible for an individual annual performance bonus, plus Capital's annual profitability bonus plus a retirement plan where Capital contributes 15% of your eligible earnings.
You can learn more about our compensation and benefits here.
* Temporary positions in Canada and the United States are excluded from the above mentioned compensation and benefit plans.
We are an equal opportunity employer, which means we comply with all federal, state and local laws that prohibit discrimination when making all decisions about employment. As equal opportunity employers, our policies prohibit unlawful discrimination on the basis of race, religion, color, national origin, ancestry, sex (including gender and gender identity), pregnancy, childbirth and related medical conditions, age, physical or mental disability, medical condition, genetic information, marital status, sexual orientation, citizenship status, AIDS/HIV status, political activities or affiliations, military or veteran status, status as a victim of domestic violence, assault or stalking or any other characteristic protected by federal, state or local law.
$106k-149k yearly est. Auto-Apply 60d+ ago
Scientist -I
Integrated Resources 4.5
Senior principal scientist job in Los Angeles, CA
A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.
This is Contract position with my direct client
Job Description
Scope A Scientist-Contractor will be responsible for technical support to the Neutrogena manufacturing facility and general marketed product support for cosmetic, personal care and OTC monograph drug products . This individual will work, under supervision, in a team environment with Operations, Supply Chain, Quality Assurance, Product Development, Technical Transfer, Analytical Development, Microbiology, Regulatory and Marketing Personnel..
Responsibilities.
Technical service support to activities related to continuous LAP manufacturing facility improvement such as execute studies to support product bulk hold time; execute raw material stability and compatibility studies. • Work collaboratively across functional groups in accomplishing the studies and implement the changes. • Conduct NC/CAPA investigations, Action Plans, and Verification/Validation Activities, root cause determination 4.
Qualifications
Qualifications
• B.S. or M.S. in Chemical Engineering, Materials/Polymer Science, Chemistry or other science discipline, 3 years professional experience; or M.S. with 0-3 years of professional experience.
• Extensive knowledge of Emulsion theory, design, and processing
• Experience with beauty products and emulsion processes
• Understanding of cGMPs and current FDA Compliance requirements is must
• Experience in developing semi-solid products or process development
• A technical knowledge base of physical chemistry, chemistry and material sciences.
• Experience with formulated products including emulsions, surfactants, toothpastes, suspensions, etc.
• Problem Solving: Proactively seek solutions; Gather and analyze information systematically; Develop alternative solutions; Think analytically and act decisively.
• Master Complexity: Competently handle day-to-day work challenges; Thrive in uncertain circumstances; Detail oriented and ability to work collaboratively across functional groups and handle multiple responsibilities and projects.
• Communication: Excellent oral and written communication skills. Write clearly and informatively; Create documents that are complete and accurate.
• Commitment: Strive to attain quality results on time; convey a sense of urgency and drive issues to closure; earn a reputation for reliability and dependability.
• Strong technical writing skills
• Understanding of compliance both from quality and regulatory standpoint
• Be able to work effectively cross functionally and accurately communicate risks and requirements.
• The ability to work independently and to meet timeline schedules.
• Requires strong technical and communication skills
• Computer literacy and full understanding of Microsoft Office
5. Can be acquired on job:
• Site specific software required by client
• SOP's and Work Instructions developed by client
Additional Information
Contact me at 732 429 1850 if interested
$117k-170k yearly est. 20h ago
Associate Scientist - Thousand Oaks, CA
Msccn
Senior principal scientist job in Thousand Oaks, CA
ATTENTION MILITARY AFFILIATED JOB SEEKERS
- Our organization works with partner companies to source qualified talent for their open roles. The following position is available to
Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers
. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post.
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Associate Scientist
What you will do
Let's do this. Let's change the world. In this vital role you will develop and execute high throughput assays to support the pipeline, contribute to the development of innovative solutions to advance our purification, analytics, and molecular assessment capabilities. Amgen is seeking an innovative Associate Scientist to join the Protein Therapeutics (PT) - Protein Chemistry team. PT is a multidisciplinary team with broad capabilities in protein engineering, expression, purification, and characterization. We are responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development.
Responsibilities
Advancing our pipeline by purifying and characterizing novel and complex molecules that will be the next generation of large molecule therapeutics
Developing novel, innovative solutions to advance our purification, analytics, and molecular assessment capabilities with automation
Analyzing and reporting data for large molecule drug candidate selection
Partnering with Project, Data Science, Analytics and Automation teams to drive innovation
Additional Qualifications/Responsibilities
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a highly collaborative, motivated candidate with these qualifications.
Basic Qualifications:
Master's degree and 1 year of protein analytics and characterization assay experience OR
Bachelor's degree and 3 years protein analytics and characterization assay experience
Preferred Qualifications:
Master's degree and 5 years of high throughput large molecule characterization experience
Demonstrated effective communication skills, ability to multi-task and work collaboratively in a cross-functional team environment
Broad experience with automated high throughput assay development, execution, and analysis
Demonstrated expertise in protein characterization, bioanalytical techniques; familiarity with cloning, purification, protein engineering, and mammalian protein expression is a plus
Demonstrated track record of independent critical thinking and creative problem-solving skill set
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Salary Range
97,797.00 USD - 110,188.00 USD
Senior principal scientist job in Thousand Oaks, CA
Employment Type: Contract Business Unit: Product and Reagent Attributes Duration: 1+ years (with likely extensions) Notes: Bachelors' degree & 2 YOE. Work onsite. Self Management. A logical and independent mind. Meticulous attention to detail and accuracy. instrumentation- experience in HPLC, UV/VIS Spectrometry
Posting Date: 03/09/2022
3 Key Consulting is hiring a Project Manager for a consulting engagement with our direct client, a leading global biopharmaceutical company.
Job Description:
Plans, conducts experiments, records and organizes data, analyzes and reports results in compliance with the respective protocol and applicable guidelines and regulations. Responsibilities include:
Follows established experimental design and protocols and performs routine tasks and studies to obtain reproducible and reliable results with limited supervision.
Plans, conducts, analyzes and records experiments, and provides interpretation of data of routine testing.
Performs method verification and qualification with moderate supervision.
Develops and implements new methods with supervision.
Skilled and/or knowledgeable in the use of standard laboratory equipment with experience in HPLC, UV/VIS Spectrometry, solid phase extraction and liquid-liquid extraction an added bonus.
Upon training, able to effectively trouble-shoot equipment and experimental difficulties.
Routinely contribute to internal reports, presentations, regulatory documents.
Participates in department-wide support efforts such as safety, recruiting and committees.
Develop and implement new protocols with moderate review.
Engage coworkers in scientific discussions.
Communicate data and interpretation of results to work group.
May train staff.
Coordinates requests and organizes resources needed to support several families of methods.
Understands when to seek input and when to make independent judgments.
Why is the Position Open?
Backfill.
Top Must-Have Skill Sets:
Skilled at developing and utilizing existing systems to ensure quality data.
Skilled and/or knowledgeable in the use of standard laboratory equipment and with one or more major laboratory instruments/techniques including HPLC.
Understands when to seek input and when to make independent judgments.
Contributes to internal/external reports, papers, presentations, regulatory documents, invention disclosure submissions and/or patents.
Must have 2 years lab experience minimum.
Ideal candidate will be able to work independently and take initiative but also collab with a team.
Day to Day Responsibilities:
Perform experiments, organize data and analyze results under minimal supervision
Monitor or follow established experimental design and protocols to perform routine tasks and studies to obtain reproducible and reliable results with limited supervision
Plan, conduct, analyze and record experimental results, and provide interpretation of data
Effectively transfer experimental methods from literature to the lab and make modifications as necessary
Develop and implement new protocols with moderate review
Engage coworkers in scientific discussions
Communicate data and interpretation of results to work group
May train staff and/or supervise others in a limited capacity
Basic Qualifications:
Pipetting, good manual dexterity in fine and gross motor manipulations, attention to detail, able to juggle multiple methods and priorities.
Degree in Biology, Biochemistry or Analytical Chemistry.
Experience in a Biopharmaceutical working environment.
Employee Value Proposition:
Career growth / opportunity.
Red Flags:
Less than 2 years' experience outside of academia in a lab environment.
Job hopping.
Interview process:
Phone screening followed by in-person interview.
We invite qualified candidates to send your resume to **************************. If you decide that you're not interested in pursuing this particular position, please feel free to take a look at the other positions on our website ******************************* You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.
Regards, 3KC Talent Acquisition Team
How much does a senior principal scientist earn in Oxnard, CA?
The average senior principal scientist in Oxnard, CA earns between $93,000 and $216,000 annually. This compares to the national average senior principal scientist range of $83,000 to $169,000.
Average senior principal scientist salary in Oxnard, CA