Sr Scientist/ Principal Investigator- Bioanalysis DMPK Biotransformation group
Senior principal scientist job in Saint Louis, MO
Title
Senior Scientist/ Principal Investigator - Bioanalysis DMPK Biotransformation
We are looking for an accomplished scientist to join our growing drug discovery DMPK and Small Molecule Bioanalysis team. Our site has grown to 120 employees and our team has grown to 8 scientists. We have developed a collaborative culture and mutual respect. Our site is part of a 2400 person growing publicly traded international organization with over 15 sites. We recently made a $4.5MM investment in our site.
The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology, and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
Position Requirements
Education and experience
BS or equivalent degree in Chemistry, Biochemistry, or related field, and greater than 15 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management or
MS in Chemistry, Biochemistry, or related field, and 7 to 10 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management or,
Ph.D. in Chemistry, Biochemistry, or related field and 3 to 5 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management
Skills and abilities
Working knowledge and awareness of general laboratory procedures.
Displays versatility and accuracy performing laboratory operations, some of which may be difficult and/or non-routine.
Ability to use a computer to compile and maintain databases for records and inventory, utilizing the appropriate software.
Ability to adhere to all safety regulations and procedures.
In-depth knowledge and specific understanding of analytical testing needed in drug discovery as it relates to DMPK.
Understanding of GMP/GLP/GCP regulations with the ability to apply these practices daily.
An attitude for quality, an eye for detail, the ability to follow written instructions and work with a minimum of supervision.
Strong Knowledge of LC-MS/MS instrumentation, troubleshooting, method development, and analysis of biological fluids and tissues, preferably on a Sciex Platform for qualitative and quantitative analysis
Responsibilities and Duties
Lead, train, and mentor colleagues to enhance analytical skills and DMPK knowledge.
Lead efforts to troubleshoot and solve method development or assay challenges.
Establish the experimental design and manage the conduct of studies in compliance with the protocol/amendments/planned changes, Best Practice Documents, and SOPs.
Perform all other duties and responsibilities of a Principal Investigator as defined in applicable SOPs
Operate analytical instrumentation and lab equipment and perform analyses according to the Operation Manuals, SOPs, and/or Best Practices.
Contribute to existing SOPs and develop new SOPs as needed.
Demonstrate an understanding of Best Practices, SOPs and Good Laboratory Practice Regulations (21 CFR, Part 58) as these relate to study-specific services provided, this job description, and general facility operations
Serve as the Company representative and point of contact to Study Directors and/or Sponsors for bioanalytical projects. This includes the establishment of a correspondence file for documenting Study Director/client exchanges including phone conversations, emails, faxes, and mail.
Provide a central internal and external scientific contact for studies within the Bioanalytical group. Represent the company by providing support for scientific posters or presentations at scientific meetings and/or client visits.
Perform method development, method qualification, and/or other study-related activities.
Determine and allocate resource needs for study execution.
Review literature to determine the most appropriate approach for project-specific bioanalytical needs.
Assure that the Lab Manager and/or Study Director is aware of any deviations from the study protocol and/or SOPs during a study and ensure that proper documentation is performed.
Review and approve raw data and reports to be sent to internal and external clients.
Assure that study data and samples are compiled, organized, inventoried, and archived at Company or transferred to the testing facility archive/client prior to or upon completion of the services, as applicable
Employees are offered a fun, fast-paced work environment with competitive pay, benefits package including medical, dental, and vision insurance, 401k with company match, stock options, and much more!
Principal/Senior Principal Scientist in Medicinal Chemistry
Senior principal scientist job in Ballwin, MO
Humanwell Pharmaceutical US, Inc. is a St. Louis, MO-based pharmaceutical research and development company focused on creating novel therapeutics to address unmet medical needs. At Humanwell, we strive to improve patients' quality of life and are dedicated to building a happier and healthier world.
We are currently seeking a highly motivated Medicinal Chemistry Leader with broad drug discovery expertise, proven project management skills, and a strong track record of leading teams. This individual will play a pivotal role in our Drug Discovery Department, directing multidisciplinary efforts to identify innovative clinical candidates. Primary Responsibilities
Lead a multidisciplinary drug discovery team to ensure scientific excellence and operational efficiency.
Design and implement medicinal chemistry strategies that incorporate structural, physicochemical, pharmacokinetic, and safety considerations to drive discovery of novel and differentiated development candidates.
Evaluate and refine design proposals from the computational chemistry group.
Direct and execute synthetic chemistry strategies to support discovery efforts.
Identify and apply emerging synthetic and purification technologies to enable efficient synthesis of novel compounds.
Assess and recommend cutting-edge technologies in drug design and discovery.
Oversee and manage external CRO relationships to ensure seamless, high-quality project execution.
Collaborate effectively with leadership and provide timely, well-organized reports.
Facilitate effective communication and interaction across functions including computational chemistry, biology, CMC, safety, and external collaborators.
Lead preclinical studies and support IND filings.
Establish intellectual property strategies for discovery programs and drive patent preparation in partnership with patent counsel.
Required Qualifications
Ph.D. in Organic or Medicinal Chemistry and at least 15+ years of industrial drug discovery experience with a strong track record of scientific innovation and clinical candidate delivery.
Demonstrated leadership of cross-functional drug discovery teams.
Broad knowledge of medicinal chemistry and related disciplines (computational chemistry, DMPK, pharmacology, and process chemistry) to progress programs from lead identification to development candidate and IND filing.
Experience with cyclic peptide design, PROTAC and Molecular Glue will be preferred.
Experience managing timelines and external chemistry resources to meet key decision points with high-quality outcomes.
Ability to develop and maintain collaborative relationships across cultures, geographies, and organizations.
Proven creativity, problem-solving, and relationship-management skills within matrix teams (internal and external).
Self-driven, entrepreneurial mindset with demonstrated success working in fast-paced, diverse teams.
Hands-on experience using computational chemistry tools and structure-based drug design principles for lead identification and optimization.
Strong background in synthetic and medicinal chemistry, evidenced by high-quality publications and/or patents.
Demonstrated ability to lead programs from initiation through lead optimization to clinical lead selection.
Excellent organizational, interpersonal, and motivational skills to inspire and guide team members.
Clear, effective communication skills to present project strategies and progress to internal and external stakeholders; ability to communicate in both English and Chinese is preferred.
Why Join Us?
This is a unique opportunity to lead and innovate in a collaborative, fast-paced environment. You will play a pivotal role in shaping our medicinal chemistry strategy, advancing our pipeline, and translating cutting-edge science into transformative therapies for patients.
We offer a competitive salary and benefits package, including health insurance, 401K, and a vacation plan. Our company is committed to diversity and inclusion, and we welcome candidates of all backgrounds to apply.
If you are interested in this position, please submit your resume and a cover letter highlighting your relevant experience and qualifications.
Staff Scientist - Pathology & Immunology
Senior principal scientist job in Saint Louis, MO
Scheduled Hours 40 Our lab is interested in understanding how microbiota and microbial metabolites interact with the host to influence chronic inflammation and fibrosis in Inflammatory bowel diseases (see Science 371:1154). The position will involve utilizing human specimens, cell culture models (macrophages and fibroblasts) and testing hypothesis in mouse models of the disease.
Designs research protocols. Assists in developing and conducting research projects, including experiment design, data analysis and documentation of experiment results. Provides critically complex research and experimentation for department/s allowing the advancement of scientific analysis and discovery.
Appropriate training in all aspects will be provided.
Job Description
Primary Duties & Responsibilities:
* Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
* Assists with grant preparation and reporting.
* Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses.
* Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
* Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods.
* Conducts literature searches related to research project.
* Performs other duties as assigned.
Working Conditions:
* Works in a laboratory environment with potential exposure to biological and chemical hazards.
* Must be physically able to wear protective equipment and to provide standard care to research animals.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Master's degree or combination of education and/or experience may substitute for minimum education.
Certifications/Professional Licenses:
No specific certification/professional license is required for this position.
Work Experience:
Laboratory Operations (3 Years)
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.
Preferred Qualifications
Education:
Ph.D. - Doctor of Philosophy
Certifications/Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Analytical Problem Solving, Communication, Computer Literacy, Computer Software Applications, Critical Thinking, Data Analysis, Data Interpretations, Detail-Oriented, Laboratory Instrumentation, Laboratory Research, Oral Communications, Recordkeeping, Self-Starter, Spreadsheets, Written Communication
Grade
R10
Salary Range
$48,000.00 - $86,900.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email **************************** or call the dedicated accommodation inquiry number at ************ and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
* Up to 22 days of vacation, 10 recognized holidays, and sick time.
* Competitive health insurance packages with priority appointments and lower copays/coinsurance.
* Take advantage of our free Metro transit U-Pass for eligible employees.
* WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
* Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
* We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We've got you covered.
* WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: ******************************
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University's policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a community of individuals who are committed to contributing to an inclusive environment - fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
Auto-ApplyScientist I Downstream Process Development
Senior principal scientist job in Saint Louis, MO
Do you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you'll help solve some of the world's toughest challenges, from giving cancer patients hope, ensuring safe drinking water and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources and tools they need to take science a step beyond.
Location/Division Specific Information
Saint Louis, MO / Pharma Services Group/ 100% Onsite
Discover Impactful Work
This position offers an opportunity to be a part of our dedicated team of Process Development Scientists. Your responsibilities will include contributing to the development, confirmation, and transfer of downstream protein purification processes to be used during manufacturing, playing a crucial role in our global operations. Working alongside customers, scientists, and other departments, you will help implement advanced solutions to our high-quality biopharmaceutical facilities.
A Day in the Life
In this role, you will:
- Perform laboratory experiments to develop, assess, or transfer protein purification processes. You will gain experience using industry standard technology such as chromatography, filtration, and UFDF.
- Learn to interpret client documents and literature to strategize approaches for successful process development and/or transfer activities.
- Communicate findings and discuss relevance of your data to a multi-discipline team consisting of upstream, downstream, and analytical scientists, quality assurance, process engineers and our customers.
Education
- Bachelor or Master of Science degree in Biology / Chemistry / Biochemistry / Chemical Engineering, or a related field.
Experience
- 0-1 years of relevant lab experience preffed.
Knowledge, Skills, Abilities
- Ability to function in a constantly evolving environment.
- High attention to detail and ability to adhere to standard procedures.
- Strong desire to learn new skills.
- Ability to work independently with excellent communication and prioritization skills.
Physical Requirements
This role requires the ability to stand for extended periods, as well as lift and perform repetitive hand motions.
Relocation Benefits
This position does not offer relocation benefits.
Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. A one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory at Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.
Apply today! ****************************
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
Accessibility/Disability Access
Job Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at ***************. Please include your contact information and specific details about your required accommodation to support you during the job application process.
*This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
Senior Beverage Scientist - Missouri ***Relocation Available to $140,000
Senior principal scientist job in Bridgeton, MO
OPEN JOB: Senior Beverage Scientist SALARY: $110,000 to $140,000 INDUSTRY: Food & Beverages IDEAL CANDIDATE
The ideal candidate will have 5+ years in beverage application and development with a variety of products such as coffee, seltzers, teas, powder bases etc.
POSITION SUMMARY:
The Senior Scientist position, within Flavors R&D team, will leverage scientific training and industrial experience to develop and scale-up new flavor products and systems for the food and beverage market. This position is expected to tackle projects with significant technical challenges, ensuring diligence in the development, scale-up, and commercialization of innovative products that deliver on business goals.
The position requires a strong ability to work cross-functionally to set goals and timetables, drive innovation, and support commercialization efforts. Additionally, this individual will support both local and global strategies and business initiatives while providing technical expertise to internal and external customers.
ESSENTIAL FUNCTIONS:
Lead and champion a culture of safety across all activities.
Drive product development, innovation, and novel applications in beverage.
Lead the conceptualization, development, and commercialization of new beverage products and technologies.
Optimize and validate the functional performance and sensory properties of various beverages.
Support the commercial team by translating unmet consumer needs into actionable science and technology strategies.
Support internal initiatives including, but not limited to: cost reduction initiatives, production efficiencies, and quality improvements.
Provide technical leadership to address complex challenges, simplifying issues by focusing on critical priorities.
Serve as a technical expert, solving broader business issues through science and technology strategies.
Develop and execute experiments to create technical data supporting the business's commercial strategy.
Design and conduct product testing, including sensory analysis and analytical testing, as well as review and analyze resulting data.
Stay updated on emerging technologies and developments in beverage, fostering strong relationships with customers, research institutions, and industry organizations.
Represent the organization in customer meetings, presenting technologies and solutions effectively.
Collaborate with Marketing, Sales, Operations, Quality, Regulatory, and Senior Management to achieve cross-functional business objectives.
Provide high-level technical support to customers, sales teams, and internal departments on beverage issues.
Deliver written and oral reports on project status, experimental results, and technical recommendations.
Ensure the integrity of the R&D laboratory through accurate record-keeping, test design, and adherence to sanitary practices.
Support and mentor other scientists within the R&D organization.
QUALIFICATIONS:
Bachelor's Degree in Food Science or a related scientific field with 10+ years of relevant work experience, or a Master's degree with 5+ years of experience.
At least 5 years of hands-on experience in the formulation and scale-up of a wide variety of beverages including, but not limited to, dairy based and dairy alternative beverages, carbonated beverages, fortified beverages, fruit drinks, energy drinks, enhanced waters, sports drinks, tea, and/or coffee beverages is required.
Experience in UHT/HTST beverage processing is preferred.
Proven track record in product formulation, specification creation, commercialization, and new technology development.
Expertise in formulation, including the use of flavors, proteins, vitamins/minerals, stabilizers, acidifiers, sweeteners, and functional ingredients in wet and dry beverage bases.
Strong understanding of functional and sensory evaluation methods.
Proficiency with computer software, including Excel, Word, and product formulation tools.
Advanced problem-solving, data analysis, and evaluation skills.
Exceptional written and verbal communication skills.
Demonstrated ability to collaborate across teams and departments, including Marketing, Quality, and Senior Leadership.
Ability to manage and prioritize multiple projects while delivering high-quality results.
Commitment to continuous learning and staying current with industry trends and innovations.
Demonstrated ability to work in and lead cross-functional teams to deliver innovative solutions and achieve commercialization milestones.
Develop new formulations in collaboration with customers, sales, & marketing
Create and document finished goods formulas for costing and production
If you are interested in pursuing this opportunity, please respond back and include the following:
Full MS WORD Resume
Required compensation
Contact information
Availability
Upon receipt, one of our managers will contact you to discuss in full
JASON DENMARK
Recruiting Manager
INTERMEDIA GROUP, INC.
EMAIL: ****************************
LINKEDIN: ****************************************
Easy ApplySenior Analytical Scientist
Senior principal scientist job in Saint Louis, MO
Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role:
In this role you will be involved with problem solving, working within project timelines, and contributing to documentation for method qualification and transfer into GMP manufacturing.
* Serve as a subject matter expert in analytical development, perform troubleshooting / provide efficient and innovative solutions, and support transfer of analytical methods to GMP QC labs.
* Utilize customer-facing skills, document experimental results, communicate results to all stakeholders, author method development and qualification documents, contribute to information for customer proposals.
* Serve as a project lead and ensure project deliverables are on quality and on time, develop multiple technical approach plans as needed to solve problems and mitigate risk, ensures process and methods are in place for efficient GMP start.
* Lead project teams, influence exemplary work in other team members, lead process improvement initiatives, scout for new technologies / emerging trends, proactively consider the impact of quality, regulatory, manufacturing, and safety requirements when planning project activities.
Who You Are:
Minimum Qualifications:
* Bachelor's Degree in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 6+ years of research experience.
OR
* Master's Degree in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 2+ years of research experience.
OR
* PhD in in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 1+ years of research experience.
Preferred Qualifications:
* Experience with protein characterization via ELISA, SPR, Isoelectric Focusing, CE-based methods, UV-Vis, and/or chromatography (HPLC/GC/IC/UPLC/SEC/HILIC).
* Experience with advanced laboratory techniques; theory and practice to enable the development of novel approaches to solve complex process and analytical problems on fast-paced projects with changing priorities.
* Knowledge of small molecule or bio-therapeutics drug development process.
* Experience with antibody-drug conjugation.
* Knowledge in Biochemistry or Organic Chemistry.
* Experience in automation in an analytical setting and instrument maintenance and troubleshooting.
* Knowledge of Microsoft Word, Excel, and PowerPoint.
* Experience with advanced data acquisition and/or statistical software systems.
* Ability to coordinate information exchange and manage data generated by contract testing labs.
RSREMD
Pay Range for this position: $68,700/yr - $132,700 yr.
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
Clinical-Scientific - Bench Scientist I
Senior principal scientist job in Chesterfield, MO
Integrated Resources, Inc., is led by a seasoned team with combined decades in the industry. We deliver strategic workforce solutions that help you manage your talent and business more efficiently and effectively. Since launching in 1996, IRI has attracted, assembled and retained key employees who are experts in their fields. This has helped us expand into new sectors and steadily grow.
Job Description:
Job Title: Clinical-Scientific - Bench Scientist I
Location: Chesterfield - MO
Duration: 12 Months+
The Associate Scientist position is available within the Conjugation and Polytides Process Development (CPPD) group in Bioprocess R&D. Working within a team setting, the successful applicant will support the development of innovative, robust, efficient, and scalable chemical and biochemical processes and technologies required for the advancement of a diverse and extensive portfolio of bio-conjugate- and polytide-derived bio therapeutics.
The position will focus on providing analytical support for process characterization studies, but may also support fellow scientist in design and execution of experiments and the necessary purification activities to produce drug substances with appropriate quality attributes.
The candidate will work across process development functions and projects covering a broad portfolio including vaccines, antibody-drug conjugates, therapeutic proteins, and oligonucleotides.
Under the guidance of senior scientists, the candidate will perform basic analysis of process intermediates and drug substances.
The candidate will also work with fellow scientists in designing and executing experiments at the laboratory scale, and based on the analyses of these studies, will be expected to develop and test new hypotheses to improve fundamental understanding of the chemical and biochemical processes, including bio-conjugation or large and small molecule combinations.
This position will support drug substance and drug substance intermediate purification activities as needed.
This position requires a highly motivated individual with the ability to work closely with other members of the laboratory and the department in a matrix environment.
This position will also collaborate with the pilot plan and manufacturing staff on experimental studies, clinical manufacturing, and process validation, including work with external contract manufacturing organizations.
Demonstrated ability to drive for results and drive innovative research programs independently.
Good understanding of chemistry/biochemistry and macromolecule analytics.
Familiarity with recent scientific literature is desirable.
Applicants should be self-motivated, organized, and capable of working independently, and in a collaborative environment.
The successful candidate will possess strong oral and written communication skills. Strong analytical and computer skills are required.
Qualifications
Qualification and work experience:
Required: B.S. degree in Chemistry, Biology, or equivalent or related field with 0-5 years of industry experience.
Proven record of delivering results in a fast paced environment and effective communication to project teams.
Desirable: 2-3 years of experience with analytical techniques for biomolecules and/or process development of biotherapeutics.
Additional Information
All your information will be kept confidential according to EEO guidelines.
With Regards,
Abhishek Singh
650-399-0881
Clinical Recruiter
Integrated Resources, Inc.
Analytical Scientist
Senior principal scientist job in Maryland Heights, MO
We are seeking a dedicated Quality Control Scientist to join our team supporting both contract development and manufacturing organization operations and a new compounded pharmaceutical manufacturing line. This role emphasizes method development, validation, and technical problem-solving for small-molecule products and compounded formulations. The ideal candidate will possess strong analytical expertise and extensive experience in pharmaceutical quality systems.
Responsibilities
* Design, develop, and validate analytical methods for compounded pharmaceutical products and small-molecule drug substances and products.
* Support method transfer activities between internal teams and external partners.
* Develop methods for impurity profiling, degradation studies, and stability testing.
* Provide technical insights for complex analytical challenges, including root cause analysis for deviations and out-of-specification results.
* Collaborate with Quality Assurance on investigations and corrective actions.
* Ensure analytical methods and documentation meet regulatory requirements for FDA submissions and CMC packages.
* Maintain compliance with cGMP and industry standards for laboratory operations.
* Participate in CDMO development projects, contributing analytical expertise to formulation and process development.
* Work at the bench as needed to execute laboratory studies and support project timelines.
* Identify and implement process improvements within QC workflows to enhance efficiency and compliance.
* Support audit readiness and contribute to maintaining a robust quality culture.
Essential Skills
* Minimum 10-15 years of experience in analytical method development and validation within a pharmaceutical environment.
* Strong knowledge of HPLC, GC, MS, dissolution, and other analytical techniques.
* Diverse experience with various drug product types, APIs, intermediates, small-molecule, and compounded pharmaceuticals.
* Understanding of regulatory guidelines (FDA, ICH) and cGMP standards.
* Excellent technical writing skills.
Additional Skills & Qualifications
* Bachelor's or advanced degree in Chemistry or a related field.
* Familiarity with compounding operations and small-molecule development preferred.
* Ability to mentor and coach others, with potential to lead teams.
* Empathetic leadership skills and an understanding of diverse employee backgrounds.
* Integrity, transparency, and a collaborative approach to decision-making.
Work Environment
The team currently includes three other chemists in the lab. The position offers a flexible day shift from Monday to Friday, along with two weeks of PTO and holiday pay. This is an excellent opportunity to join a rapidly growing business, with the chance to establish and shape processes in a dynamic environment equipped with new GC's and HPLC's, using the latest Open Lab Software with Agilent.
Job Type & Location
This is a Contract to Hire position based out of Maryland Heights, MO.
Pay and Benefits
The pay range for this position is $48.08 - $72.11/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Maryland Heights,MO.
Application Deadline
This position is anticipated to close on Dec 22, 2025.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Formulation Scientist : 3101-1
Senior principal scientist job in Chesterfield, MO
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
Contractor will be working on various analytical techniques (particle characterization techniques- MFI, HIAC) and will analyze various samples, write reports and present data.
o Ability to work in a lab with analytical instrumentation is desirable
o Experience with testing biological molecules is desirable
o Good understanding and basic knowledge of fundamental formulation development concepts is a plus
o Good understanding of particle characterization techniques such as HIAC, MFI is a plus
o Good understanding and practical skills in modern analytical techniques, especially analytical tools such as SEC, iCE, CGE is a plus
o Evidence of ability to identify and solve problems, making decisions from limited alternatives, can operate with autonomy
o Good communication and writing skills (formatting reports, documents, organizing data)
Minimum education level:
BS in chemistry/biochemistry/chemical engineering/pharmaceutical sciences/ or equivalent
Minimum years' experience: 0 - 2
Position Comments visible to MSP and Supplier:
Qualifications
BS
Additional Information
Best Regards,
Akriti Gupta
**************
Morristown, NJ 07960
Crop Genome Editing Scientist II
Senior principal scientist job in Chesterfield, MO
At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice.
Crop Genome Editing Scientist II
Position Overview:
As a Genome Editing Scientist II, you will spearhead research projects aimed at developing advanced delivery systems for genome editing components in crop plants. Your role will involve collaborating across diverse teams to develop and implement research proposals, evaluating new delivery technologies, and staying current with scientific literature to incorporate emerging technologies. You will design and execute experiments to test novel approaches for introducing molecular cargo into plant cells, apply knowledge of plant development and reproductive biology, and develop protocols to enhance efficiency across diverse germplasm. Your work will also involve evaluating and optimizing methods to bypass traditional limitations in plant transformation systems, collaborating with molecular tool developers, and presenting findings to internal stakeholders and at scientific conferences.
YOUR TASKS AND RESPONSIBILITIES:
* Lead, design, and conduct research projects focused on developing advanced delivery systems for genome editing components in crop plants;
* Collaborate across diverse teams to develop and implement outcome-driven research proposals;
* Evaluate and benchmark new delivery technologies against existing platforms;
* Stay current with scientific literature to incorporate emerging technologies;
* Design and execute experiments to test novel approaches for introducing molecular cargo into plant cells;
* Apply knowledge of plant development and reproductive biology to identify optimal intervention points;
* Develop protocols that enhance efficiency across diverse germplasm;
* Evaluate and optimize methods that bypass traditional limitations in plant transformation systems;
* Collaborate with molecular tool developers to integrate delivery systems with cutting-edge technologies;
* Analyze experimental data to guide iterative improvement;
* Present findings to internal stakeholders and at scientific conferences.
WHO YOU ARE:
Bayer seeks an incumbent who possesses the following:
Required Qualifications:
* PhD in plant biology, developmental biology, plant physiology, or related field;
* 3+ years of post-PhD research experience in plant science;
* Strong knowledge of plant development, reproductive biology, and tissue differentiation;
* Experience with plant modification methods and molecular biology techniques;
* Demonstrated expertise in microscopy and cellular manipulation techniques;
* Track record of innovative thinking and successful technology development;
* Evidence of scientific leadership through publications and/or patents;
* Outstanding written and verbal communication abilities;
* Track record of innovative thinking and solving big problems;
* Ability to work collaboratively in a team environment.
Preferred Qualifications:
* Experience with reproductive biology, embryo development, or specialized tissue culture;
* Experience with corn;
* Knowledge of plant regeneration systems and developmental pathways;
* Familiarity with advanced molecular delivery approaches;
* Background in cell-specific targeting or tissue-specific expression;
* Understanding of plant germplasm diversity challenges;
* Understanding of bioinformatic tools for analyzing editing outcomes;
* Background in synthetic biology or nucleic acid chemistry.
Employees can expect to be paid a salary between $99,699.20 - $149,548.80 Additional compensation may include a bonus or incentive compensation (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.. This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, an applicant's skills and prior relevant experience, certain degrees and certifications, and other relevant factors.
This posting will be available for application until at least January 5, 2026.
#LI-US
YOUR APPLICATION
Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Bayer is an E-Verify Employer. Location:United States : Missouri : Chesterfield Division:Crop Science Reference Code:858368 Contact Us Email:hrop_*************
Easy ApplyMass Spectrometry Scientist
Senior principal scientist job in Chesterfield, MO
**At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice.**
**Mass Spectrometry Scientist**
**YOUR TASKS AND RESPONSIBILITIES:**
+ Develop/validate/implement bioanalytical methods for protein or small molecules on LCMS platforms in a timely manner
+ Perform and handle sample preparation procedures using different extraction techniques from different systems
+ Maintain and perform advanced troubleshooting of complex LC systems and mass spectrometers using scientific background to address technical challenges. Maintain laboratory compliance with safety regulations.
+ Create and maintain comprehensive laboratory documentation.
+ Applies state-of-art know-how to solve complex problem in Mass Spectrometry field.
**WHO YOU ARE:**
Bayer seeks an incumbent who possesses the following:
**Required Qualifications:**
+ PhD with minimum of 3 years biochemistry/analytical chemistry experience, or MS with minimum of 5 years relevant experience, BS with minimum of 7 years relevant experience.
+ A high level of competency in protein identification, characterization, quantitation and post-translational modification with mass spectrometry.
+ Conducts research and contributes to research projects, technologies, publications, intellectual property, or trade secrets
+ Experience and knowledge in global regulatory requirements for Biotech product submission.
+ Great communication and networking skills to ensure productive interaction with key customers.
Employees can expect to be paid a salary between $99,699.20 - $149,548.80. Additional compensation may include a bonus or incentive compensation (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.. This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, an applicant's skills and prior relevant experience, certain degrees and certifications, and other relevant factors.
This posting will be available for application until at least January 5, 2026.
**YOUR APPLICATION**
Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Bayer is an E-Verify Employer.
**Location:** United States : Missouri : Chesterfield
**Division:** Crop Science
**Reference Code:** 858796
**Contact Us**
**Email:** hrop_*************
Easy ApplyTech Transfer Scientist/Engineer.
Senior principal scientist job in Chesterfield, MO
Global Channel Management is a technology company that specializes in various types of recruiting and staff augmentation. Our account managers and recruiters have over a decade of experience in various verticals. GCM understands the challenges companies face when it comes to the skills and experience needed to fill the void of the day to day function. Organizations need to reduce training and labor costs but at same requiring the best "talent " for the job.
Job Description
This position is responsible for taking an active role in the
technical transfer of processes into the clinical manufacturing facility
and/or transfer of processes out to commercial manufacturing or a CMO.
Some of the detailed responsibilities will include:
- Lead meetings to facilitate the Tech Transfer process.
- Identify, communicate, track, and hold team members accountable for project deliverables.
- Evaluate lab-scale processes and define the scaled up process for the clinical production facility.
- Interface with development scientists and propose options to resolve process fitting issues.
- Capture and convey process details by preparing detailed Process Flow Diagrams
- Provide raw material forecasts for clinical campaigns.
- Write master batch records and solution records for clinical production.
- Monitor the progression of the clinical campaigns and provide data summaries to stakeholders
- Write campaign summaries and provide information for regulatory filings
- Participate in and/or initiate continuous improvement projects.
- Provide support for engineering studi
Qualifications
Qualifications
Background in a biological or engineering discipline (Biotechnology, Biochemistry, Biochemical Engineering, or equivalent).
Experience with project management tools and methodologies is desirable.
What is the minimum education experience required?:
Backg
Additional Information
$53hr
12 MONTHS
Bench Scientist
Senior principal scientist job in Chesterfield, MO
At Real we're always looking for new and ambitious people to help deliver exceptional service levels, change the lives of the candidates we represent and partner with some of the world's best pharmaceutical, biotechnology and medical companies.
As specialists in recognising talent we pride ourselves on not just finding the best people for our client partners but on our ability to spot the best and brightest talent to work for us. We are also renowned for providing training and long-term career opportunities to help our employees be the best they can be, so they can continue to deliver the expertise Real has become famous for.
Relationships are at the heart of everything we do and ensure that our clients and candidates continue to work with us again and again. This ethos is also what shapes how we work as a business. We encourage and reward knowledge sharing and have various support networks and international forums to enable our employees to keep up-to-date with changes happening across their industries and share local insight to deliver true global perspectives.
Job Description
The qualified candidate will join Pfizer's Bioassay and Impurities Testing group, which is part of the Analytical R&D organization located in Chesterfield, MO to enable the development of biological therapeutics at Pfizer.
KEY FEATURE:
The position will be part of a highly matrixed team responsible for developing analytical methodologies (ELISA, qPCR) and strategies needed to progress biotherapeutic products through the pipeline.
The scientist filling this position will work within a highly-matrixed team setting on a variety of modalities including vaccines, viral constructs, therapeutic proteins, and monoclonal antibodies.
Will work in a cGMP testing environment performing sample testing, method development, and method qualification.
Qualifications
SKILLS & QUALIFICATIONS
Experience with ELISA and DNA techniques (qPCR).
Intermediate proficiency in Microsoft Office (Excel, Word, and Outlook) is required.
Must be able to understand and follow standard operating procedures
Experience working in a cGMP environment and experience with LIMS are desired but not required.
Must be able to pipette accurately, pay attention to detail, follow SOPs, learn quickly, and work in a highly matrixed environment.
Experience:
0-2 years
Education:
Bachelor of Science
Additional Information
All your information will be kept confidential according to EEO guidelines.
IF THIS IS THE JOB OPPORTUNITY FOR YOU GIVE ME A CALL AT ************ ASAP! I want to know more about your preferences.
If in case you know someone who might be interested for this, feel free to pass it along. I look forward to hearing from you!
Associate Quality Scientist
Senior principal scientist job in Saint Louis, MO
Work Your Magic with us! Start your next chapter and join MilliporeSigma.
Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role:
At MilliporeSigma, the Associate Quality Scientist will perform Quality Control activities in support of release of cGMP products, including routine testing (in-house and compendial).
Perform routine testing and peer review of release samples through adherence to applicable GMP requirements.
Utilize written procedures to perform routine and non-routine product testing.
Revise procedures through use of the Document Management System (DMS) following Good Documentation Practices (GDP).
Work in accordance with current GMPs and demonstrate proper laboratory safety and housekeeping practices.
Participate in method development and validation activities to support product testing.
Contribute to support function of the laboratory through participation in laboratory audits to maintain compliance.
Participate in deviation investigations.
Contribute to process improvement projects.
Physical Attributes:
Wear personal protective equipment including but not limited to: safety glasses, gloves and respirator.
Who You Are
Minimum Qualifications:
Bachelor's Degree in Chemistry, Chemical Engineering, or other Life Sciences discipline
1+ years of GMP laboratory experience
Preferred Qualifications:
General laboratory techniques (theory and practice).
Experience with various laboratory equipment.
Working Knowledge of Good Manufacturing Practices for pharmaceutical manufacturing (21 CFR 210 & 211 and/or ICH Q7A).
Knowledge of Microsoft Word, Excel and Access.
Strong time management, verbal and written communication skills.
Pay Range for this position: $23.00-$42.00 per hour.
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
Senior Scientist - Regulatory Cardiac Safety/Electrophysiology (Scientist II)
Senior principal scientist job in Saint Charles, MO
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.
The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.
In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.
In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.
Job Description
The Senior Scientist ensures study design; execution and reporting align with regulatory and client project specifications. The Senior Scientist provides critical client consultation throughout study life cycle and ensures lab compliance to study design. This role will support Electrophysiology projects including cardiac safety screening in a GLP-compliant electrophysiology lab and serve as a Principal Investigator for regulated studies. This role requires technical expertise, portfolio leadership, leadership competencies, and proficiency in client communication within a contract research organization.
Senior Scientist - Regulatory Cardiac Safety/Electrophysiology (Scientist II) responsibilities include, but are not limited to, the following:
The Senior Scientist is a scientific leadership position, responsible for providing guidance and alignment between our customer base, the industry at large, commercial teams and service operations. This role is a hands-on laboratory-based role and will be collaborative and influential in a broad network of business functions in support of delivering high quality services to our valued customers, and driving business growth, brand recognition, and alignment with Eurofins core competencies. This position will train and mentor junior staff, responsible to take informed decision to move projects ahead, set direction, champion change and directly contribute to achieving departments goals and strategies.
* Develops client and stakeholder relationships through technical leadership and collaboration
* Manages client projects in all phases of study life cycle from study design to reporting
* Provides guidance and oversight for compliance and scientific integrity of the studies to ensure that studies are performed in a compliant manner
* Understands and follows all procedures and processes required for work performed under Regulatory Compliance (i.e. GxP, FDA/GLP and GCP, OECD, CLIA, etc.) and completes annual GLP training
* Directs investigations of service operations, such as deviation reports, non-conforming reports, corrective action reports, etc. Produces documentation according to established standards
* Drafts and approves operations documents to assure consistency with regulatory standards and requirements. (I.e. SOPs, batch records, training records, etc.)
* Responsible for data generation, review, analysis review and ensuring accuracy and integrity of reporting
* Provides scientific guidance that supports technical writing and final review of Validation Plans and Reports as required
* Supports client services team in generating proposals, RFPs, study plans and scope of work preparation. Assists pricing team in completing custom pricing and cost analysis
* Completes required training and supports 100% of Employee Health and Safety requirements
* Manages responsible use of confidential IT and business systems, as required
* Ensures accurate data management and reporting, with the highest integrity, and manages quality control on project data and reports
* Accountable for delivering to unit and site key performance metrics (quality, delivery on time)
* Supports site goals and demonstrates Eurofins' competencies, as defined in the job plan
* Provides training to colleagues and external end users, when required
* Performs other duties, as assigned
Qualifications
Basic Minimum Education Qualifications:
* M.A. or M.S. with minimum 5 years relevant experience
OR
* Ph.D. with minimum 3 years relevant experience
Basic Minimum Qualifications:
* Demonstrated experience in manual patch clamp electrophysiology in a GLP-compliant laboratory is a plus.
* Scientific expertise in Ion Channel electrophysiology and applications to execute safety pre-clinical studies.
* Technical experience and knowledge in supporting compound cardiac safety profiling within drug discovery programs, from early drug discovery to IND submission life cycle.
* Experience developing client relationships, supporting technical correspondence, drafting and presenting scientific proposals to clients.
* Experience in drafting and executing equipment and method validation according to 21CFR11 compliance.
* Authorization to work in the United States indefinitely without restriction or sponsorship.
The Ideal Candidate Possesses the Following:
* Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health.
* Excellent interpersonal, verbal and written skills, including ability to prepare detailed scientific reports and group presentations.
* Demonstrates a working understanding of international regulatory requirements and aptitude to stay relevant on topical scientific publications.
* Ability to support project management, plan and coordinate multiple projects simultaneously, with appropriate allocation of available resources.
* Demonstrated experience in working effectively with lab operations, business development, marketing, and outsourcing stakeholders.
* Experience with leading and influencing cross-functional teams effectively
Additional Information
Position is full-time, with overtime as needed. Candidates currently living within a commutable distance of St. Charles, MO are encouraged to apply.
* Excellent full time benefits including comprehensive medical coverage, dental, and vision options
* Life and disability insurance
* 401(k) with company match
* Paid vacation and holidays
Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.
Associate Scientist
Senior principal scientist job in Saint Louis, MO
Canopy Biosciences, a Bruker Company, is a rapidly growing and fast-paced biotechnology company headquartered in St. Louis, Missouri. We are committed to providing cutting-edge Spatial Biology products and services to the academic, biotech and biopharma research communities. Our team of dedicated scientists is passionate about Spatial Biology and recognizes its potential to transform our understanding and eventual diagnosis of disease. We offer competitive salaries, comprehensive benefits, and a collaborative and stimulating research environment.
Bruker is one of the world's leading analytical instrumentation companies, covering a broad spectrum of advanced solutions serving the life sciences and other markets. We employ more than 8,500 employees worldwide and we have representation at over 90 locations. Bruker has been at the forefront of innovation for 60 years and is poised for additional strong growth in the future. Biotechnology, and in particular Spatial Biology, are key to Bruker's future diversification and will be generously fostered as we pursue our development of transformative solutions. At Bruker we innovate with integrity, and we invite you to consider the following role.
Responsibilities
We are looking for a Research Associate to join our R&D department. The successful candidate will become part of our R&D (Development) team in St. Louis and will be involved in day-to-day laboratory activities related to Product and Application development. Broadly, these activities consist of tissue preparation and performance of
in-situ
immunofluorescent and/or FISH-based biomarker detection assays and analysis of data. The ideal candidate will have a basic background in histology, imaging, and image analysis. Prior experience in immunology, neuroscience or biomarker assay development is desirable but not a precondition.
Responsibilities
Responsibilities may include, but are not limited to:
Performs a range of lab procedures and assays related to multiplex immunofluorescence imaging, including tissue sectioning, fixation and permeabilization, fresh-frozen tissue preparation, and PBMC isolation.
Performs assigned tasks according to SOPs and using appropriate laboratory techniques.
Maintains laboratory notebooks, SOP documents, and digital databases.
Meticulously maintains sample and reagent inventories.
Performs sample intake, QC, processing, and accessioning.
May participate in reagent and product manufacturing.
Manages, monitors, and maintains equipment, facilities, and supplies. This will include routine handling and lifting of laboratory supplies and bench-top equipment.
Works in a professional and collaborative manner with coworkers.
May interface with customers during technical support.
Provides operational support for testing activities including reagent preparation, cleaning activities, and equipment maintenance.
Works independently and exercises good judgement and problem-solving skills when required.
Qualifications
Qualification and Skills
Minimum BSc. in Biology, Genetics, Biochemistry, or related field.
Experience in histology and/or microscopy is strongly preferred.
Ability to work both independently and in a team-oriented setting.
Strong attention to detail.
At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $57K and $97K provides an opportunity to progress as you grow and develop within a role.The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.
Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.
Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions
Auto-ApplyR&D Scientist - Chemistry, Medical Laboratory
Senior principal scientist job in Saint Louis, MO
Kelly Science & Clinical is seeking a **Medical Laboratory Associate Scientist** for a **contract-to-hire ( ~7-12 month temporary position before being considered for conversion to permanent)** role with the R&D department of a biotechnology company in **St. Louis, MO** . If you're passionate about bringing scientific discoveries to life and ready to advance your career, trust **The Experts at Hiring Experts** .
**This position requires professional analytical chemistry experience in a high-complexity testing laboratory. Candidates must have hands-on experience with liquid chromatography and/or mass spectrometry to be considered.**
**Key Responsibilities**
+ Perform laboratory testing for **RUO/CLIA high-complexity** workflows.
+ Conduct **QA/QC** on analytical results and documentation.
+ Maintain laboratory reagents, supplies, and inventories.
+ Support biomarker development for **neurodegenerative disease** programs.
+ Accurately record and report results in paper or electronic systems.
+ Develop and revise **SOPs** , ensuring compliance with safety and quality policies.
+ Assist project scientists and manage multiple priorities to meet deadlines.
**Qualifications**
+ **Bachelor's degree or higher** in Chemistry, Biology, or related field with **3+ years** of professional research and/or clinical lab experience.
+ **OR,** **MT/CLS degree** with **1+ year** of clinical laboratory experience.
+ **Required:** Professional experience in **analytical chemistry** within a **GMP or CLIA high-complexity laboratory** . Academic experience cannot replace this requirement.
+ **Required:** Hands-on experience with **liquid chromatography and/or mass spectrometry in a clinical or industry setting (under GMP, GLP, and/or CLIA regulations preferred)**
+ Experience working with **human biological specimens** (e.g., blood) and biosafety procedures.
+ **Preferred:** Experience with immunoassays.
+ Strong organizational, documentation, and communication skills.
+ Proficiency with **MS Office (Excel)** and database entry.
**Job Details**
+ **Job Type:** Contract-to-hire (temp-to-perm)
+ **Location:** St. Louis, MO
+ **Pay Rate:** ~$30-35/hour, depending on relevant clinical laboratory experience
+ Work on impactful projects in **neurodegenerative disease research** .
+ Collaborative R&D environment with opportunities for professional growth.
As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here (********************************************************************* for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly Science & Clinical?
Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world's most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.
About Kelly
Work changes everything. And at Kelly, we're obsessed with where it can take you. To us, it's about more than simply accepting your next job opportunity. It's the fuel that powers every next step of your life. It's the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life-just ask the 300,000 people we employ each year.
Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly's Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.
Senior Meat Scientist
Senior principal scientist job in Bridgeton, MO
Balchem Corporation develops, manufactures, and markets specialty ingredients that improve and enhance the health and well-being of life on the planet, providing state-of-the-art solutions and the finest quality products for a range of industries worldwide. Our corporate headquarters is located in Montvale, New Jersey and we have a broad network of sales offices, manufacturing sites, and R&D centers, primarily located in the US and Europe. Founded in 1967, Balchem is a publicly traded company (NASDAQ BCPC ) with annual revenues over $900 million and a market cap exceeding $4.0 billion. The company consists of three business segments: Human Nutrition & Health; Animal Nutrition & Health; and Specialty Products. Balchem employs over 1,400 people worldwide who are engaged in diverse activities, committed to developing the company into global market leadership positions. To learn more about our dynamic, stable and growing company, visit ****************
POSITION SUMMARY
This Meat Scientist position, within the Applications R&D team, will leverage scientific training and industrial experience to support and develop protein product opportunities (animal and plant-based) and complementary nutritional applications. The role is expected to tackle projects with significant technical challenges, ensuring diligence in the development, scale-up, and commercialization of innovative products that deliver on business goals.
In this role, the successful candidate will provide technical and thought leadership, collaborate with external laboratories and universities, and play a pivotal role in establishing an on-site meat science laboratory. The position requires a strong ability to work cross-functionally to set goals and timetables, drive innovation, and support commercialization efforts. Additionally, this individual will support both local and global strategies and business initiatives while providing technical expertise to internal and external customers.
This role not only emphasizes meat product development but also involves driving broader innovation in protein applications and supporting the commercial team by translating unmet consumer needs into actionable science and technology strategies.
ESSENTIAL FUNCTIONS
Lead and champion a culture of safety across all activities.
Drive product development, innovation, and novel applications in meat science.
Provide technical leadership to address complex challenges, simplifying issues by focusing on critical priorities.
Serve as a technical expert, solving broader business issues through science and technology strategies.
Lead the conceptualization, development, and commercialization of new meat products and technologies.
Develop and execute experiments to create technical application data supporting the business's commercial strategy.
Design, conduct, and analyze product tests, including sensory analysis, physical testing, and analytical evaluations.
Validate and optimize the functional performance and sensory properties of ingredients in meat and protein applications (both animal and plant-based).
Stay updated on emerging technologies and developments in meat science, fostering strong relationships with customers, research institutions, and industry organizations.
Support new product opportunities for protein and complementary nutritional applications.
Represent the organization in customer meetings, presenting technologies and solutions effectively.
Collaborate with Marketing, Operations, Quality, Regulatory, and Senior Management to achieve cross-functional business objectives.
Provide technical support to customers, sales teams, and internal departments on meat application issues.
Deliver written and oral reports on project status, experimental results, and technical recommendations.
Support the commercial team by translating unmet consumer needs into actionable science and technology strategies.
Lead the design and setup of an on-site meat science laboratory, ensuring proper maintenance and operation of equipment.
Ensure the integrity of the R&D laboratory through accurate record-keeping, test design, and adherence to sanitary practices.
QUALIFICATIONS:
Bachelor s Degree in Food Science or a related scientific field with 10+ years of relevant work experience, or a Master s degree with 5+ years of experience.
At least 5 years of hands-on experience in meat product development is required.
Proven track record in new technology development, product innovation, and commercialization.
Expertise in meat product manufacturing, raw material components, and variability in production processes.
Strong understanding of functional and sensory evaluation methods.
Proficiency with computer software, including Excel, Word, and product formulation tools.
Advanced problem-solving, data analysis, and evaluation skills.
Exceptional written and verbal communication skills.
Demonstrated ability to collaborate across teams and departments, including Marketing, Quality, and Senior Leadership.
Ability to manage and prioritize multiple projects while delivering high-quality results.
Commitment to continuous learning and staying current with industry trends and innovations.
Demonstrated ability to work in and lead cross-functional teams to deliver innovative solutions and achieve commercialization milestones.
WORKING CONDITIONS:
Work involves the use of typical food science lab equipment, computers, and instrumentation. Some business travel by automobile, bus, train, and plane is required.
Occasionally, must be able to work on their feet for extended periods in the lab, pilot, and manufacturing plant.
May be required to lift and carry large boxes or bags, and the work environment may occasionally be noisy, wet, slippery, and subject to temperature variations.
#HP123
Balchem is committed to a workplace culture that values and promotes diversity, inclusion, equal employment opportunities, and a work environment free of harassment and hostility.
Bench Scientist I
Senior principal scientist job in Saint Louis, MO
Duration: 18+ Month (With possible extension) Minimum education experience required: Associates degree with 5 years of experience/ Bachelor's degree with 1 year of experience Experience required: 0-3 years Top 3 critical skills: Buffer preparation; Concentration by UV; pH
Job Description:
Proficient with wet chemistry and analytical instrumentation (emphasis on proteins desired). Primary roles include SDS-PAGE analysis, buffer preparation and routine testing (appearance, pH, moisture, concentration by UV, colorimetric assay, etc.) for a high throughput Protein Analytics laboratory. Responsible for general laboratory and operational support, including assisting scientific staff with lab maintenance activities. Proficiency with Excel spreadsheets is required. Basic laboratory skills including use of balances and adjustable pipets, ability to work with Excel spreadsheets, and attention to detail are required
Qualifications
Minimum education experience required:
Associates degree with 5 years of experience/ Bachelor's degree with 1 year of experience
Experience required:
0-3 years
Top 3 critical skills:
Buffer preparation; Concentration by UV; pH
Additional Information
All your information will be kept confidential according to EEO guidelines.
Scientist I Downstream Process Development
Senior principal scientist job in Saint Louis, MO
Do you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you'll help solve some of the world's toughest challenges, from giving cancer patients hope, ensuring safe drinking water and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources and tools they need to take science a step beyond.
Location/Division Specific Information
Saint Louis, MO / Pharma Services Group/ 100% Onsite
Discover Impactful Work
This position offers an opportunity to be a part of our dedicated team of Process Development Scientists. Your responsibilities will include contributing to the development, confirmation, and transfer of downstream protein purification processes to be used during manufacturing, playing a crucial role in our global operations. Working alongside customers, scientists, and other departments, you will help implement advanced solutions to our high-quality biopharmaceutical facilities.
A Day in the Life
In this role, you will:
• Perform laboratory experiments to develop, assess, or transfer protein purification processes. You will gain experience using industry standard technology such as chromatography, filtration, and UFDF.
• Learn to interpret client documents and literature to strategize approaches for successful process development and/or transfer activities.
• Communicate findings and discuss relevance of your data to a multi-discipline team consisting of upstream, downstream, and analytical scientists, quality assurance, process engineers and our customers.
Education
• Bachelor or Master of Science degree in Biology / Chemistry / Biochemistry / Chemical Engineering, or a related field.
Experience
• 0-1 years of relevant lab experience preffed.
Knowledge, Skills, Abilities
• Ability to function in a constantly evolving environment.
• High attention to detail and ability to adhere to standard procedures.
• Strong desire to learn new skills.
• Ability to work independently with excellent communication and prioritization skills.
Physical Requirements
This role requires the ability to stand for extended periods, as well as lift and perform repetitive hand motions.
Relocation Benefits
This position does not offer relocation benefits.
Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. A one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory at Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.
Apply today! ****************************
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
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