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$50k-100k yearly est. 1d ago
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Principal Scientist (Residual Impurities)
MacRogenics, Inc. 4.8
Research scientist job in Rockville, MD
Job Category: Development
Apply now
Posted : November 5, 2025
Full-Time
On-site
Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA
MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position
The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams.
Responsibilities and Job Duties:
Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release.
Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness.
Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations.
Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts.
Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders.
Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions.
Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support.
Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays.
Author and/or review SOPs, technical protocols and reports, and regulatory filings.
Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership.
Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences.
Participate in industry consortia on relevant topics and align internal strategies with industry practice.
Qualifications
Education & Experience
Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development;
or
Master's degree with 12+ years of related industry experience;
or
Bachelor's degree with 14+ years of related industry experience
2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams
Prior experience in preparing analytical sections of IND, BLA and regulatory responses.
Knowledge, Skills and Abilities
Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA)
Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges
Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones
Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment
Skilled in stakeholder management, with clear, proactive, and collaborative communication style
Strong technical writing skills and attention to detail in documentation and data review
Experience mentoring and developing scientific staff; promotes open communication and teamwork
Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements
Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays
Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines.
Demonstrated leadership and influence in cross‑functional matrix environments
Preferred Qualifications
Familiarity with potency assays, physiochemical assays and other characterization assays
Knowledge in novel techniques on detecting and analyzing residual impurities
Strong publication record and external scientific presence
Experience in fostering partnership with clients through CDMO service
Supervisory Responsibilities
Yes. This role may supervise Associate Scientist and/or Scientist
Additional Information
The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits.
The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.
Statement
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service.
Equal Opportunity Employer/Veterans/Disabled
Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies.
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$129.5k-197.5k yearly 2d ago
Principal Research Scientist - AI & Machine Learning
Novateur Research Solutions
Research scientist job in Ashburn, VA
Novateur stands for Innovation. We value creativity, vision, collaboration, and above all, ambition to innovate. Novateur Research Solutions is an R&D firm located in Northern Virginia, developing intelligent systems that push the boundaries of computer vision, AI, and large-scale learning.
We are hiring a Principal ResearchScientist to lead cutting-edge programs in AI, computer vision, and intelligent systems. This role offers leadership opportunities to define new research directions and shape next-generation technologies.
Responsibilities:
• Serve as PI or co-PI on government-funded R&D programs.
• Conceive, design, and oversee research in learning systems, spatiotemporal modeling, and geo-localization.
• Publish, present, and contribute thought leadership to the AI community.
• Mentor research staff and guide proposal development.
Requirements:
• PhD with 7+ years of research experience.
• Demonstrated leadership in ML, vision, or scientific computing.
• Record of funding, publications, and technical impact.
• U.S. Citizen or Permanent Resident.
Preferred:
• Experience with multimodal learning, uncertainty quantification, or causal inference.
Why Novateur?
Join a team that values creativity and initiative. At Novateur, you'll lead transformative projects that redefine what's possible in intelligent systems.
Company Benefits:
Novateur offers competitive pay and benefits comparable to Fortune 500 companies that include a wide choice of healthcare options with generous company subsidy, 401(k) with generous employer match, paid holidays and paid time off increasing with tenure, and company paid short-term disability, long-term disability, and life insurance.
We offer a work environment which fosters individual thinking along with collaboration opportunities within and beyond Novateur. In return, we expect a high level of performance and passion to deliver enduring results for our clients.
$86k-125k yearly est. 13h ago
Scientist, Discovery
Arcellx Inc. 4.0
Research scientist job in Rockville, MD
Who We Are Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.
Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.
What Matters to Us
Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.
Arcellx Core Values
* Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work.
* Think 'we' before 'me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals.
* Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right.
How You'll Make a Difference
As a Scientist, your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients.
The "Fine Print" - What You'll Do
* Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies.
* Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed.
* Develop new methods, technologies and processes when necessary for project.
* Exercise significant technical discretion in the design, execution and interpretation of experiments.
* Communicate progress and project recommendations to team members.
Skills and Experience We Look For
* BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience.
* Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis.
* Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation).
* Preference for experience in drug development, immunology or protein engineering.
* The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams.
Rewards at Arcellx
Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.
The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.
Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more.
Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to ****************
#LI-Onsite
$100k-120k yearly 46d ago
Fiber Laser Scientist II
NSS 4.4
Research scientist job in Herndon, VA
Fiber Laser Scientist Herndon, VA
While working as a Fiber Laser Scientist at Fibertek, you will lead the design and development, integration, and test of advanced fiber laser systems typically with performance requirements beyond the state-of-the-art. Fibertek is a leader in the design, development, and delivery of advanced laser systems and technologies for military and aerospace applications.
Your Job We are looking for and experienced and motivated fiber laser scientist or engineer to join a multi-disciplinary team and lead the design and demonstration of advanced laser systems. Example focus missions include space-based laser communications, lidar for tactical defense applications, earth-sensing lidar, and navigational lidars for planetary and docking missions. Fibertek's engineering teams simultaneously tackle laser optical performance beyond state-of-the-art while engineering systems for performance on challenging platforms with limited size, mass, and power and over stressing vibration, thermal, and/or radiation conditions. Delivered systems make a national impact to customers at NASA and throughout the defense community. The work-load will at times include multiple concurrent projects with a mix of short duration research programs and longer duration technology maturation programs resulting in a work culture that is team-oriented, intellectually stimulating, and consistently rewarding.
Lead the engineering development of unique laser designs through modeling fiber laser performance, design analysis, component specification, and hardware assembly, integration, and test
Coordinate and support the build, alignment, and performance characterization of fiber lasers including multi-stage amplifiers, phase & amplitude modulation implementation, spectral and coherent beam combining
Coordinate and perform formal acceptance and qualification testing
Participate in customer interactions including formal technical reviews
Required Skills and Experience To exceed in this Fiber Laser Scientist role, you'll need the below expertise and experience:
MS or PhD in Physics or Optical Engineering w/ a minimum of 5 years of direct hands-on fiber laser experience including designing, building, characterizing laser systems
Knowledge of the laser theory and industry best practices associated with fiber laser systems including continuous wave lasers, pulsed, high peak power fiber, advanced fiber architectures, single-frequency injection locked lasers, low frequency noise lasers, electrical and thermal sub-systems.
Expertise in laser physics of fiber lasers and amplifiers, including ytterbium, erbium, and/or thulium gain materials.
Familiarity with relevant nonlinear processes and impacts to laser performance. Examples include Stimulated Brillouin Scattering, Four-Wave Mixing, Stimulated Raman Scattering, and Transverse Modulational Instability.
Foundational understanding of fiber-optic components including types of fibers, pump lasers, couplers, modulators, isolators, mode-field adapters, polarization components, and others.
Knowledge of tools for modeling fiber laser performance such as Matlab, RP Power Fiber or equivalent software
Ability to design and execute experiments validating laser system performance and correlate the results with the expected performance
Strong communication and documentation skills for efficient multidisciplinary communication
US citizenship required
Please apply today for this full-time Herndon-based Fiber Laser Scientist role and join the leader in the development of state-of-the-art laser and electro-optic solutions. Why Fibertek, Inc?
At FIBERTEK, Inc. we pride ourselves in our innovation and customer success focused culture enabled by a creative and relaxed work environment with minimal bureaucracy. Fibertek fosters a progressive learning environment that values inspiration, promotes professional challenge and encourages personal growth. We offer a competitive and incentivized compensation package with excellent benefits.
Fibertek, Inc. is an equal opportunity and affirmative action employer. Applicants are considered regardless of race, sex, gender identity, sexual orientation, religion, national origin, disability, protected Veteran status, age or any other protected characteristic in accordance with applicable law. If you need assistance or an accommodation for any part of the application process, please contact us by phone at ************ or via email at ***************.
$75k-103k yearly est. Easy Apply 60d+ ago
Senior/Junior BI Scientist
Psomagen Inc.
Research scientist job in Rockville, MD
Senior/Junior Bioinformatics Scientist
About Psomagen
Psomagen Inc. is a rapidly growing biotechnology company renowned for providing a variety of genomics-based molecular assay solutions to research and clinical communities. We are looking to expand our bioinformatic analysis capabilities to broaden our service area into Multi-Omics solutions. We are searching for a highly motivated Senior Manager in Bioinformatic analysis with extensive experience in NGS based bioinformatic analysis.
Position Overview
Are you seeking an opportunity where you can lead the technological advancement of precision medicine in a well-established research environment? Do you want to use your knowledge and experience to lead the expansion of a rapidly growing biotechnology company? If you are eager to pursue a challenge in developing new biotechnological assays with well-motivated colleagues, join our bioinformatics team!
The ideal candidate will take ownership of the development, execution, and improvement of analysis pipelines for Next-Generation Sequencing (NGS) services. The individual may also execute collaborative projects with external researchers and join the customer facing discussion. This role will contribute to growing, coaching, and aligning the team towards the shared vision of delivering high quality data analysis for our customers.
This role is an on-site position in Rockville, MD
Key Responsibilities
● Generate analytical pipelines and perform data analysis using the Illumina Dragen suite.
● Perform bioinformatic analyses on NGS data, ensuring accuracy and reliability of the dataset and conduct quality control assessments of NGS data, adhering to industry standards and company protocols
● Develop and maintain reproducible NGS data analysis pipelines in the AWS environment, ensuring the reliability and scalability of workflows.
● Develop HTML-based data analysis reports for customers, summarizing and visualizing raw and analyzed datasets.
● Supervise bioinformatics team members, including task delegation, performance evaluation, and continuous professional development of junior team members.
● Support research projects, including managing large amounts of data, monitoring, and running the developed pipelines.
● Generate the documentation related to the pipelines (Reports, README, etc).
● Stay abreast of current developments in public bioinformatics tools, pipelines and databases.
● Participation in customer-facing discussions with field application scientists to support business development/customer services activities.
● Planning and writing various ad-hoc scripts and visualization scripts to analyze specific data and interpret results.
● Demonstrate good judgment in selecting methods and techniques for obtaining solutions while resolving a wide range of issues in creative ways.
● Research independently within a team environment to develop and improve genomics analysis solutions.
Qualifications
● Junior Level: Bachelor's or Master's degree in Biology, Bioinformatics, Computer Science, or a related field with 1-3 years of relevant experience.
● Senior Level: Master's degree with 3+ years of industry experience OR a Ph.D. in Bioinformatics, Computer Science, Biology, Genetics, or a similar field.
● Strong knowledge and proficiency in Bash, R, Python, and other relevant programming languages for bioinformatics pipeline development.
● Proficiency in NextFlow is highly preferred and other workflow languages are a plus.
● Experience operating the Illumina DRAGEN package from command line or web-based UI is a plus.
● Advanced experience working with Linux environments and familiarity with HPC systems for large-scale NGS data analysis.
● Experience using bioinformatics tools and familiarity with genomics databases.
● Good communication, interpersonal and presentation skills for team work.
● Ability to work as part of a team and with external collaborators.
● Ability to independently and reliably complete tasks and projects.
● Detail oriented and team-oriented leadership
What We Offer
● Competitive base salary with a performance-based commission structure.
● Comprehensive medical, dental, and vision insurance.
● 401(k) retirement plan with company match.
● Generous paid time off (PTO) and holidays.
● Opportunity to lead a pioneering business unit within a rapidly growing company.
● Target Salary Range: $47,000 - $100,000. Salary is determined within this range based on the qualifications.
$47k-100k yearly Auto-Apply 11d ago
Associate Scientist I
Microbac Laboratories, Inc. 4.0
Research scientist job in Sterling, VA
Come join our family! Microbac Laboratories is an essential business offering competitive pay and benefits including medical, dental, vision, life insurance, disability, generous paid time off including vacation, holidays and flex-time, a wellness program, referral bonus, tuition reimbursement and more!
Whether you are just starting your career in science or looking to further it, Microbac will put you on the path of an exciting career with room to grow. Quality, safety, giving back to our communities, diversity and inclusion, customer success and employee wellbeing are part of our core culture. We are looking for motivated individuals to join our family as an Associate Scientist I .
ABOUT MICROBAC
Microbac Laboratories, Inc. is a premier commercial laboratory testing firm that partners with clients worldwide, offering laboratory solutions to the life science, food and nutrition, and environmental industries and serves our clients with the utmost expertise and respect for their market requirements, constraints, and challenges. We embody a company-wide commitment to exceptional customer experience, which has been refined over nearly 50 years of trusted, analytical and measurement experience.
Through our network of laboratories, offices, and field services, we have the flexibility to meet the unique requirements for each client, project, and scope.
As a privately held third-party testing company, Microbac operates with a commitment to safety, quality, and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and nutrition and life science markets.
JOB SUMMARY
The Associate Scientist I, working in an accredited commercial laboratory, is responsible for assisting with the conduct of microbiological assays and associated activities to determine antimicrobial efficacy of household and commercial cleaning products.
ESSENTIAL FUNCTIONS:
Following established SOP's and adhering to state, federal and other accrediting body requirements, collect information about the antimicrobial properties of substances/samples to support the analytical testing needs of our clients for such purposes as quantitative or qualitative analysis, and product development
Perform laboratory housekeeping duties to include autoclaving and glassware processing
Prepare necessary standards, solutions, reagents, media, etc., required for sample analyses
Perform equipment and instrumentation set up
Operate basic and specialized laboratory instrumentation
Prepare and analyze samples
Accurately record observations and data and interpret results
Assists in the development and validation of new analytical methods
Assists in the development of new laboratory procedures
Assist department supervisors and managers with staff training
Sign off on final certificates of analysis
Contribute to writing, editing, and reviewing SOP's
Monitor and address sample backlog issues
Perform peer review of data to ensure accuracy
Maintain accurate, up to date logs, notebooks, and equipment records
Perform necessary laboratory administrative functions such as filing paperwork, photocopying, reviewing of data, and entering data into computerized LIMS
Comply with and promote Personnel, Safety, and Quality Program
MINIMUM REQUIREMENTS:
Bachelor's degree from a four-year accredited institution in a related field of applied science
Prior analytical testing experience
Above average knowledge of principles, terminology, practices, techniques, and instrumentation commonly used in a laboratory setting
Ability to interpret data and prepare reports
Ability to effectively prioritize work and manage time to meet deadlines and rush orders
Computer literacy
Ability to work with delicate laboratory equipment
Ability to communicate effectively in both written and verbal formats
WORKING CONDITIONS AND PHYSICAL REQUIREMENTS:
The physical demands and working conditions described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Physical Requirements:
While performing the duties of this job, the employee is regularly required to use hands to finger, handle, or feel objects, tools; talk or hear. The employee is required to stand, walk, and sit.
The employee must regularly lift and/or move up to 25 pounds. Specific vision abilities required by this job include color vision and depth perception.
Working Conditions:
While performing the duties of this job, the employee will be in a general laboratory and office environment.
The noise level in the work environment is usually moderate.
This job may require travel less than 20%
As a privately held third-party testing company, Microbac operates with a commitment to safety, quality and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and life science markets.
OTHER:
This is not an exhaustive list of all duties an employee may be required to perform. Microbac reserves the right to revise the job description at any time.
Employment is at-will. Microbac, promotes a drug-free, alcohol-free workplace. Applicants considered for hire must pass a drug test before beginning work. Refusal to submit to testing will result in disqualification of further employment consideration.
Microbac is an Equal Opportunity Employer - We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. All qualified applicants will receive consideration for employment.
$55k-79k yearly est. Auto-Apply 39d ago
Research Associate, Microbiology (#1876)
Battelle National Biodefense Inst
Research scientist job in Frederick, MD
Job Description
BACKGROUND
The National Biodefense Analysis and Countermeasures Center (NBACC) is a one-of-a-kind facility located on Fort Detrick in Frederick MD and is dedicated to defending the nation against biological threats. Its work supports DHS and National biodefense preparedness planning, response, emerging threat characterization and bioforensic analyses. It is the first national laboratory created by DHS in response to biodefense gaps identified following the Amerithrax attacks of 2001 and has been operated by the Battelle National Biodefense Institute (BNBI) since 2006. Since its inception, NBACC and its staff have filled critical shortfalls in our scientific knowledge of biological agents needed to protect the public and defend the Nation from biological threats, whether naturally occurring, accidental, or deliberate and provided federal law enforcement with scientific data to support the investigation and attribution of biocrimes and protection of the US bioeconomy.
NBACC includes two centers: the National Bioforensic Analysis Center (NBFAC), which conducts the technical analyses in support of federal law enforcement investigations, and the National Biological Threat Characterization Center (NBTCC), which conducts experiments and studies to obtain data required for a better understanding of biological vulnerabilities and hazards. Together these centers offer a unique national resource for understanding the risks posed by biological agents and emerging technologies to inform biodefense policy and response planning and the operational capability to support the investigation, prosecution, and prevention of biocrimes and bioterrorism.
PRIMARY FUNCTION
Works with a team of scientists in the NBTCC at the NBACC to develop, manage and analyze research that addresses specific scientific questions of national significance in support of biodefense preparedness, response and recovery. Areas of research include a range of topics related to the physical, biological and/or pathogenic properties of viral or toxin agents. Work will be performed in select agent-approved state-of-the-art Biosafety Level (BSL) - 2, 3, & 4 and Animal BSL (ABSL) - 2, 3, & 4 facilities fully staffed and equipped with a wide range of technologies useful for biodefense and infectious disease research.
MINIMUM REQUIRED QUALIFICATIONS
Bachelor of Science (or equivalent) in a scientific discipline or engineering and a minimum of 4 years of related experience or a Master's degree and a minimum of 2 years of related experience.
Experience should include at least one of the following methods: mammalian cell culture; virus, pseudovirus, viral vector, or virus-like particle propagation and titration; cell-based assays and laboratory automation; immunostaining of cells; PCR/qPCR/RT-qPCR/dd PCR; next generation sequencing; heterologous protein expression; solid phase peptide and protein synthesis; cell-based toxicity and/or electrophysiological assays; affinity and/or native protein purification and quantification; high performance and/or fast protein liquid chromatography.
Experience supporting laboratory logistical functions (e.g., reagent and supply inventory, purchasing, coordination of instrument maintenance, laboratory upkeep and organization) is required.
Intermediate scientific proficiency in laboratory functions. Possesses the ability to identify issues with laboratory protocols, procedures, and experimental plans.
Proficiency and clarity of oral and written communications are essential.
Exemplary organizational skills with a proven track record of working effectively both independently and as a team player.
Knowledge or experience with biocontainment facilities and procedures, laboratory safety, biosurety, and decontamination is desirable.
Skills and experience to support laboratory activities and work in accordance with NBACC's management system (e.g., ISO).
Must be a citizen of the United States, able to obtain and maintain an interim secret clearance leading to a top-secret clearance, suitability for DHS, and a favorable adjudication of the Department of Justice (DoJ) for select agent access.
Participation in the Immunization Program, Medical Surveillance Program, and enrollment in the Personnel Reliability Program (PRP) is required.
May be required to participate in NBACC's alternative work and/or on-call schedule, dependent upon business needs.
PRIMARY RESPONSIBILITIES
Provides technical and laboratory expertise to perform research in BSL-2, 3, & 4 laboratories aimed at addressing viral and/or toxin characterization knowledge gaps, such as evaluation of viral/toxin production, environmental decay, and virulence/toxicity.
Collaborates with other scientific staff to identify and implement continued process improvements to NBTCC cell culture operations.
Provides support to virus and toxin-based assays in BSL-2, 3, & 4 laboratories based upon NBTCC project requirements.
Contributes in matrixed and cross-functional research teams that may include Aerobiology, Bacteriology, and Comparative Medicine (veterinary) staff.
Adapts to potentially rapidly changing and high tempo project requirements to address national security issues with flexibility and resiliency.
Collects/analyzes technical and programmatic data as part of a project team in support of Project Lead or Principal Investigator. Performs quality control and peer review of data as assigned.
Develops high-quality draft protocols and task-specific procedures. Identifies and documents inconsistencies among NBACC Standard Operating Procedures (SOPs) or deviations from them and promptly reports these to the Project Lead and/or management.
Supports Principal Investigators during the writing of technical reports through review and summary of experimental records, initial processing and QC of raw data, and technical review of methods and data.
May be appointed as a Lab Space Manager (LSM) and/or Biological Select Agents and Toxins (BSAT) designee.
Possesses the ability to work on multiple scientific tasks simultaneously, while performing assignments outside of area of expertise.
Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.
Follows established procedures on routine work, requires instruction only on new assignments, and is self-sufficient in monitoring and reporting on quality, and compliance.
Participates in the testing and evaluation of new technologies and protocols including writing and updating SOPs, work instructions and forms to improve NBACC's ability to serve its customers.
Identifies departures from the Quality Management System (QMS) and initiates actions to investigate and prevent such occurrences.
With minimal supervision, operates, maintains, and characterizes the performance of equipment ensuring the reagents and supplies are maintained and used properly.
Serves as a member of a team in developing, validating, and maintaining methods for identifying and characterizing biological threat agents.
Must be a team player, communicate clearly, be open to hearing ideas and suggestions from others, diffuse situations, and exercise empathy and patience with colleagues.
Must have the ability to multi-task, maintain composure under pressure, and utilize effective time management skills to prioritize tasks.
Must be a self-starter driven by an eagerness to succeed, maintain flexibility, adapt to change in a productive and positive manner, learn new concepts, and utilize critical thinking to resolve complex problems.
Maintains appropriate records.
Performs other duties as assigned/authorized.
$46k-70k yearly est. 17d ago
Associate Scientist
Us Tech Solutions 4.4
Research scientist job in Gaithersburg, MD
US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well.
Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset.
Job Description
• BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations.
• This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data.
• The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment.
Qualifications
Education:
• Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field.
Experience:
• For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience.
• For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience.
Additional Information
Special Skills/ Abilities
• Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred.
• Good documentation, writing and communication skills in a team based setting are essential.
$56k-84k yearly est. 1d ago
Associate Scientist II, Molecular & Computational Biology
Tonix Pharmaceutical 3.8
Research scientist job in Frederick, MD
About Tonix* Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace SymTouch (sumatriptan injection) 3 mg and Tosymra (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults.
Tonix's development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA.
Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md.
Please visit ******************* for specifics on the pipeline.
* All of Tonix's product candidates are investigational new drugs or biologics and have not been approved for any indication.
Position Overview
Tonix Pharmaceuticals is seeking a highly motivated Associate Scientist to join our multidisciplinary R&D team at the Frederick Research & Development Center. This role integrates computational protein structure analysis with hands-on molecular biology and protein biochemistry. The successful candidate will contribute to host-directed therapeutic discovery, antiviral platforms, and vaccine design by combining AI/ML-based protein modeling with molecular biology and protein science to generate, express, and analyze protein targets.
Key Responsibilities
* Perform protein structure modeling and design using platforms such as AlphaFold2/3, ESM, RFdiffusion, ProteinMPNN, and NetMHC.
* Build and refine bioinformatics workflows for large-scale sequence and structural analysis of host and viral proteins
* Perform molecular cloning, PCR, DNA and RNA isolation, bacterial transformation, and mutagenesis to generate expression constructs.
* Carry out protein expression and purification followed by protein characterization
* Collaborate with Tonix's imaging and cell biology teams to translate computational predictions into testable hypotheses in assays and animal models.
* Contribute to the development of user-friendly computational pipelines and visualization tools for internal scientists.
* Document and communicate results in reports, regulatory filings, and presentations to internal teams, collaborators, and external partners.
* Maintain awareness of emerging computational biology technologies to enhance Tonix's drug discovery capabilities.
Required Qualifications
* B.S. or M.S. in Microbiology, Biochemistry, Bioinformatics, Computational Biology, or related field.
* Hands-on experience with protein structure prediction and computational protein design tools.
* Familiarity with core molecular biology and protein biochemistry methods (PCR, cloning, bacterial expression, Western blotting).
* Strong communication skills and ability to work in cross-functional teams within Tonix's integrated discovery pipeline.
Preferred:
* Experience with cloud computing platforms (Google Cloud, AWS) for large-scale protein modeling.
* Exposure to machine learning approaches in protein design and immunology.
* Prior experience with protein engineering for therapeutic applications.
* Track record of contributions to publications, posters, or conference presentations.
* Proficiency in Python, especially ML/AI packages. Experience in Linux operating systems and shell programming is desirable.
Recruitment & Staffing Agencies
Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes.
Compensation & Benefits
Annualized base salary ranges from $60,000 to $90,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit.
Tonix provides a comprehensive compensation and benefits package which includes:
* Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs
* Pet Insurance
* Retirement Savings 401k with company match and annual discretionary stock options
* Generous Paid Time Off, Sick Time, & Paid Holidays
* Career Development and Training
Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.
$60k-90k yearly 55d ago
Research Scientist & Clinical Psychologist
Maryland Treatment Centers 3.5
Research scientist job in Rockville, MD
Postdoctoral ResearchScientist & Clinical Psychologist - PTSD & Addiction Research
Location: Rockville, MD | Full-Time
Join a dynamic team advancing evidence-based treatment for addiction and PTSD.
Maryland Treatment Centers (MTC) is seeking a full-time ResearchScientist and Clinical Psychologist to support innovative addiction research within our Rockville treatment center. This role offers the chance to develop a research-oriented career in substance use disorder (SUD) and trauma treatment while working alongside a multidisciplinary clinical team.
What You'll Do:
· Coordinate a clinical trial for the treatment of PTSD taking place within a residential addiction treatment setting.
· Provide direct clinical services (Written Exposure Therapy for PTSD) as a study therapist on the project.
· Supervise research staff and assist with data collection and analysis.
· Collaborate with senior researchers on publications, grant development, and new studies.
· Mentor trainees and participate in extern supervision and teaching.
Why Join Us:
· Be part of a robust research division housed within a community treatment program
· Work in a supportive, collaborative, and mission-driven environment.
· Receive mentorship, professional development, and travel support for research dissemination.
· Grow into leadership roles in clinical research or program development.
What We're Looking For:
· PhD or PsyD in Clinical Psychology (or related field).
· Licensed or license-eligible in Maryland (supervision possible).
· Interest or experience in addiction and trauma research preferred.
· Masters-level clinicians with research curiosity encouraged to apply (e.g., LCPC, LCSW).
$35k-59k yearly est. 60d+ ago
Lead Residual Impurity Scientist - Biologics
MacRogenics, Inc. 4.8
Research scientist job in Rockville, MD
A biopharmaceutical company seeks a Principal Scientist to lead the development of residual impurity assays for biologic products. This role demands strong technical leadership, project management, and a collaborative spirit in a fast-paced environment. Candidates should hold a Ph.D. with over 6 years of relevant experience. The role offers significant support in both professional growth and performance-driven compensation.
#J-18808-Ljbffr
$87k-114k yearly est. 2d ago
Discovery Scientist
Arcellx Inc. 4.0
Research scientist job in Rockville, MD
Arcellx (************************ is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx's mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible.
Primary Objective:
Arcellx is seeking Scientists (levels
Associate Scientist
to
Senior Scientist
, depending on skill and experience) to collaborate in the innovation, discovery and development of protein and cell-based therapies. The successful candidate will work closely with a dedicated team of protein engineers and more broadly with scientists in other departmental groups (e.g. immunology, translation and manufacturing) to identify, produce, characterize and optimize recombinant proteins for use as therapeutic agents in a variety of oncology indications. The candidate will bring to the role expertise in protein engineering as well as a strong track record of innovation and creativity.
Main Responsibilities:
Responsibilities will depend, in part, on hiring level, but are likely to include some or all of the following:
Collaborate with other scientists to design, generate and characterize recombinant proteins, including biopharmaceutical products.
Develop and execute selection and screening strategies using phage, yeast and mammalian display.
Evaluate existing and emerging technologies, techniques and tools enhance products and streamline discovery workflows.
Independently plan, design, execute, record and analyze experiments.
Summarize and present data in internal meetings and discussions.
Write and review technical protocols and reports. Coauthor scientific abstracts, manuscripts and presentations.
Manage and drive the advancement of internal projects, products or technology initiatives.
Preferred Qualifications:
Preferred qualification will depend, in part, on hiring level, but are likely to include some or all of the following:
PhD in the life sciences (e.g. Biochemistry, Chemistry, Chemical Engineering, Biology, immuno-oncology), with minimum of 2 years post-degree experience in protein engineering.
Extensive experience in the design, construction, expression, characterization and optimization of recombinant proteins.
Experience with biopharmaceutical product design and lead optimization is ideal.
Experience in the design and execution of selection and screening strategies, utilizing phage display (or a related display method).
Proficiency with high throughput screening, sequencing and characterization of bacterial clones.
Experience with optimizing expression yield and quality. Experience with multiple protein expression systems (e.g. bacterial, yeast or mammalian systems) is preferred.
Experience utilizing and developing appropriate methods for assessment of protein-protein interactions (e.g. ELISA, Octet BLI, Biacore SPR, MSD)
Experience with sequence analysis software (e.g. SnapGene, Sequencher, Lasergene, BLAST, etc.), including construct and primer design and sequence confirmation.
Programming experience with Python and/or R (R Studio) is ideal.
Experience in oncology, immunology, and translational research is ideal.
Submit cover letter and resume to: **************
Without exception, applicants must submit both a cover letter and resume to be considered for these positions and must have experience as described above.
$75k-111k yearly est. Auto-Apply 60d+ ago
Senior/Junior BI Scientist
Psomagen Inc.
Research scientist job in Rockville, MD
Job Description
Senior/Junior Bioinformatics Scientist
About Psomagen
Psomagen Inc. is a rapidly growing biotechnology company renowned for providing a variety of genomics-based molecular assay solutions to research and clinical communities. We are looking to expand our bioinformatic analysis capabilities to broaden our service area into Multi-Omics solutions. We are searching for a highly motivated Senior Manager in Bioinformatic analysis with extensive experience in NGS based bioinformatic analysis.
Position Overview
Are you seeking an opportunity where you can lead the technological advancement of precision medicine in a well-established research environment? Do you want to use your knowledge and experience to lead the expansion of a rapidly growing biotechnology company? If you are eager to pursue a challenge in developing new biotechnological assays with well-motivated colleagues, join our bioinformatics team!
The ideal candidate will take ownership of the development, execution, and improvement of analysis pipelines for Next-Generation Sequencing (NGS) services. The individual may also execute collaborative projects with external researchers and join the customer facing discussion. This role will contribute to growing, coaching, and aligning the team towards the shared vision of delivering high quality data analysis for our customers.
This role is an on-site position in Rockville, MD
Key Responsibilities
● Generate analytical pipelines and perform data analysis using the Illumina Dragen suite.
● Perform bioinformatic analyses on NGS data, ensuring accuracy and reliability of the dataset and conduct quality control assessments of NGS data, adhering to industry standards and company protocols
● Develop and maintain reproducible NGS data analysis pipelines in the AWS environment, ensuring the reliability and scalability of workflows.
● Develop HTML-based data analysis reports for customers, summarizing and visualizing raw and analyzed datasets.
● Supervise bioinformatics team members, including task delegation, performance evaluation, and continuous professional development of junior team members.
● Support research projects, including managing large amounts of data, monitoring, and running the developed pipelines.
● Generate the documentation related to the pipelines (Reports, README, etc).
● Stay abreast of current developments in public bioinformatics tools, pipelines and databases.
● Participation in customer-facing discussions with field application scientists to support business development/customer services activities.
● Planning and writing various ad-hoc scripts and visualization scripts to analyze specific data and interpret results.
● Demonstrate good judgment in selecting methods and techniques for obtaining solutions while resolving a wide range of issues in creative ways.
● Research independently within a team environment to develop and improve genomics analysis solutions.
Qualifications
● Junior Level: Bachelor's or Master's degree in Biology, Bioinformatics, Computer Science, or a related field with 1-3 years of relevant experience.
● Senior Level: Master's degree with 3+ years of industry experience OR a Ph.D. in Bioinformatics, Computer Science, Biology, Genetics, or a similar field.
● Strong knowledge and proficiency in Bash, R, Python, and other relevant programming languages for bioinformatics pipeline development.
● Proficiency in NextFlow is highly preferred and other workflow languages are a plus.
● Experience operating the Illumina DRAGEN package from command line or web-based UI is a plus.
● Advanced experience working with Linux environments and familiarity with HPC systems for large-scale NGS data analysis.
● Experience using bioinformatics tools and familiarity with genomics databases.
● Good communication, interpersonal and presentation skills for team work.
● Ability to work as part of a team and with external collaborators.
● Ability to independently and reliably complete tasks and projects.
● Detail oriented and team-oriented leadership
What We Offer
● Competitive base salary with a performance-based commission structure.
● Comprehensive medical, dental, and vision insurance.
● 401(k) retirement plan with company match.
● Generous paid time off (PTO) and holidays.
● Opportunity to lead a pioneering business unit within a rapidly growing company.
● Target Salary Range: $47,000 - $100,000. Salary is determined within this range based on the qualifications.
$47k-100k yearly 12d ago
Research Associate, Aerobiology (#1889)
Battelle National Biodefense Inst
Research scientist job in Frederick, MD
Job Description
BACKGROUND
The National Biodefense Analysis and Countermeasures Center (NBACC) is a one-of-a-kind facility located on Fort Detrick in Frederick MD and is dedicated to defending the nation against biological threats. Its work supports DHS and National biodefense preparedness planning, response, emerging threat characterization and bioforensic analyses. It is the first national laboratory created by DHS in response to biodefense gaps identified following the Amerithrax attacks of 2001 and has been operated by the Battelle National Biodefense Institute (BNBI) since 2006. Since its inception, NBACC and its staff have filled critical shortfalls in our scientific knowledge of biological agents needed to protect the public and defend the Nation from biological threats, whether naturally occurring, accidental, or deliberate and provided federal law enforcement with scientific data to support the investigation and attribution of biocrimes and protection of the US bioeconomy.
NBACC includes two centers: the National Bioforensic Analysis Center (NBFAC), which conducts the technical analyses in support of federal law enforcement investigations, and the National Biological Threat Characterization Center (NBTCC), which conducts experiments and studies to obtain data required for a better understanding of biological vulnerabilities and hazards. Together these centers offer a unique national resource for understanding the risks posed by biological agents and emerging technologies to inform biodefense policy and response planning and the operational capability to support the investigation, prosecution, and prevention of biocrimes and bioterrorism.
PRIMARY FUNCTION
As part of the NBACC Aerobiology Team, the Research Associate works with an interdisciplinary team of scientists in the NBTCC to develop, manage, and analyze research projects focused on characterization of the physical, biological and/or pathogenic properties of infectious biological aerosols in order to address specific scientific questions of national significance in support of biodefense preparedness, response and recovery planning.
MINIMUM REQUIRED QUALIFICATIONS
Bachelor of Science (or equivalent) in a scientific discipline or engineering, and a minimum of 4 years of related experience.
Relevant experience related to the use of aerosol generation and sampling equipment, including air flow measurement, conditioning of air flows, sampler collection efficiency assessment, and/or particle size measurement.
Experience with statistics is also desirable.
Experience utilizing LabView, or related software/hardware, for control of laboratory equipment/processes is desirable.
Intermediate scientific proficiency in laboratory functions. Possesses the ability to identify issues with laboratory protocols, procedures, and experimental plans.
Proficiency and clarity of oral and written communications are essential.
Exemplary organizational skills with a proven track record of working effectively both independently and as a team player.
Knowledge or experience with biocontainment facilities and procedures, laboratory safety, biosurety, and decontamination is desirable.
Skills and experience to support laboratory activities and work in accordance with NBACC's management system (e.g., ISO).
Must be a citizen of the United States, able to obtain and maintain an interim secret clearance leading to a top-secret clearance, suitability for DHS, and a favorable adjudication of the Department of Justice (DoJ) for select agent access.
Participation in the Immunization Program, Medical Surveillance Program, and enrollment in the Personnel Reliability Program (PRP) is required.
May be required to participate in NBACC's alternative work and/or on-call schedule, dependent upon business needs.
PRIMARY RESPONSIBILITIES
Leverages experience to support the design and execution of studies related to the sampling of infectious biological aerosols.
Participates in the testing and evaluation of new technologies and protocols to improve the group's ability to serve its customers.
Possesses the ability to work on multiple science tasks simultaneously, while performing assignments outside of area of expertise.
Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.
Follows established procedures on routine work, requires instruction only on new assignments, and is self-sufficient in monitoring and reporting on quality, and compliance.
Participates in the testing and evaluation of new technologies and protocols including writing and updating NBACC Standard Operating Procedures (SOPs), work instructions and forms to improve NBACC's ability to serve its customers.
Identifies departures from the Quality Management System (QMS) and initiates actions to investigate and prevent such occurrences.
With minimal supervision, operates, maintains, and characterizes the performance of equipment ensuring the reagents and supplies are maintained and used properly.
Serves as a member of a team in developing, validating, and maintaining methods for identifying and characterizing biological threat agents.
Must be a team player, communicate clearly, be open to hearing ideas and suggestions from others, diffuse situations, and exercise empathy and patience with colleagues.
Must have the ability to multi-task, maintain composure under pressure, and utilize effective time management skills to prioritize tasks.
Must be a self-starter driven by an eagerness to succeed, maintain flexibility, adapt to change in a productive and positive manner, learn new concepts, and utilize critical thinking to resolve complex problems.
Maintains appropriate records.
Performs other duties as assigned/authorized.
$46k-70k yearly est. 19d ago
Associate Scientist
Us Tech Solutions 4.4
Research scientist job in Gaithersburg, MD
US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************
We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well.
Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset.
Job Description
• BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations.
• This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data.
• The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment.
Qualifications
Education:
• Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field.
Experience:
• For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience.
• For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience.
Additional Information
Special Skills/ Abilities
• Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred.
• Good documentation, writing and communication skills in a team based setting are essential.
$56k-84k yearly est. 60d+ ago
Associate Scientist II, Molecular & Computational Biology
Tonix Pharmaceuticals Inc. 3.8
Research scientist job in Frederick, MD
Job Description
About Tonix*
Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya™ (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace SymTouch (sumatriptan injection) 3 mg and Tosymra (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults.
Tonix's development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA.
Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md.
Please visit ******************* for specifics on the pipeline.
*All of Tonix's product candidates are investigational new drugs or biologics and have not been approved for any indication.
Position Overview
Tonix Pharmaceuticals is seeking a highly motivated Associate Scientist to join our multidisciplinary R&D team at the Frederick Research & Development Center. This role integrates computational protein structure analysis with hands-on molecular biology and protein biochemistry. The successful candidate will contribute to host-directed therapeutic discovery, antiviral platforms, and vaccine design by combining AI/ML-based protein modeling with molecular biology and protein science to generate, express, and analyze protein targets.
Key Responsibilities
Perform protein structure modeling and design using platforms such as AlphaFold2/3, ESM, RFdiffusion, ProteinMPNN, and NetMHC.
Build and refine bioinformatics workflows for large-scale sequence and structural analysis of host and viral proteins
Perform molecular cloning, PCR, DNA and RNA isolation, bacterial transformation, and mutagenesis to generate expression constructs.
Carry out protein expression and purification followed by protein characterization
Collaborate with Tonix's imaging and cell biology teams to translate computational predictions into testable hypotheses in assays and animal models.
Contribute to the development of user-friendly computational pipelines and visualization tools for internal scientists.
Document and communicate results in reports, regulatory filings, and presentations to internal teams, collaborators, and external partners.
Maintain awareness of emerging computational biology technologies to enhance Tonix's drug discovery capabilities.
Required Qualifications
B.S. or M.S. in Microbiology, Biochemistry, Bioinformatics, Computational Biology, or related field.
Hands-on experience with protein structure prediction and computational protein design tools.
Familiarity with core molecular biology and protein biochemistry methods (PCR, cloning, bacterial expression, Western blotting).
Strong communication skills and ability to work in cross-functional teams within Tonix's integrated discovery pipeline.
Preferred:
Experience with cloud computing platforms (Google Cloud, AWS) for large-scale protein modeling.
Exposure to machine learning approaches in protein design and immunology.
Prior experience with protein engineering for therapeutic applications.
Track record of contributions to publications, posters, or conference presentations.
Proficiency in Python, especially ML/AI packages. Experience in Linux operating systems and shell programming is desirable.
Recruitment & Staffing Agencies
Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes.
Compensation & Benefits
Annualized base salary ranges from $60,000 to $90,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit.
Tonix provides a comprehensive compensation and benefits package which includes:
Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs
Pet Insurance
Retirement Savings 401k with company match and annual discretionary stock options
Generous Paid Time Off, Sick Time, & Paid Holidays
Career Development and Training
Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.
$60k-90k yearly 26d ago
Research Scientist & Clinical Psychologist
Maryland Treatment Centers, Inc. 3.5
Research scientist job in Rockville, MD
Job Description
Postdoctoral ResearchScientist & Clinical Psychologist - PTSD & Addiction Research
Location: Rockville, MD | Full-Time
Join a dynamic team advancing evidence-based treatment for addiction and PTSD.
Maryland Treatment Centers (MTC) is seeking a full-time ResearchScientist and Clinical Psychologist to support innovative addiction research within our Rockville treatment center. This role offers the chance to develop a research-oriented career in substance use disorder (SUD) and trauma treatment while working alongside a multidisciplinary clinical team.
What You'll Do:
· Coordinate a clinical trial for the treatment of PTSD taking place within a residential addiction treatment setting.
· Provide direct clinical services (Written Exposure Therapy for PTSD) as a study therapist on the project.
· Supervise research staff and assist with data collection and analysis.
· Collaborate with senior researchers on publications, grant development, and new studies.
· Mentor trainees and participate in extern supervision and teaching.
Why Join Us:
· Be part of a robust research division housed within a community treatment program
· Work in a supportive, collaborative, and mission-driven environment.
· Receive mentorship, professional development, and travel support for research dissemination.
· Grow into leadership roles in clinical research or program development.
What We're Looking For:
· PhD or PsyD in Clinical Psychology (or related field).
· Licensed or license-eligible in Maryland (supervision possible).
· Interest or experience in addiction and trauma research preferred.
· Masters-level clinicians with research curiosity encouraged to apply (e.g., LCPC, LCSW).
$35k-59k yearly est. 21d ago
Research Associate, Discovery
Arcellx Inc. 4.0
Research scientist job in Rockville, MD
Arcellx (************************ is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx's mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible.
Primary Objective:
The Research Associate position is open to candidates who can demonstrate the ability to thrive in a modern and fast-paced biotechnology environment. A successful candidate will work with a cross-functional team responsible for the discovery and development of novel therapeutic proteins. The incumbent will be a result-oriented self-starter with a commitment to teamwork and reliability.
Main Accountabilities:
The main responsibilities will include but are not limited to:
Working with other scientists to design, generate and characterize recombinant proteins.
Execute selection and screening strategies used in discovery workflows.
Plan, execute, record and analyze experiments.
Preferred Qualifications:
Master's in the life sciences (e.g. Biology, Genetics, Biochemistry, Chemistry, Chemical Engineering), with a minimum of one year of work experience in a laboratory setting.
Proficient with molecular biology methods, including: primer design, PCR, gel electrophoresis, plasmid DNA preparation, cloning and sequence analysis.
Experience in with characterization of recombinant proteins, including but not limited to ELISA, MSD, SDS-PAGE, protein quantitation, etc..
Competencies:
Commitment to ethical scientific investigations and rigorous experimental methods.
Ability and desire to multitask and function in a fast-paced entrepreneurial environment.
Demonstrated ability to think critically and analyze and interpret data independently.
Sense of urgency in performance of duties.
Interpersonal skills that promote a collaborative and productive lab environment.
Effective and efficient written and oral communication skills.
Submit cover letter and resume
Without exception, applicants must submit both a cover letter and resume to be considered for these positions and must have experience in one of the fields listed above.
$49k-78k yearly est. Auto-Apply 60d+ ago
Research Scientist & Clinical Psychologist
Maryland Treatment Centers, Inc. 3.5
Research scientist job in Rockville, MD
Postdoctoral ResearchScientist & Clinical Psychologist - PTSD & Addiction Research
Location: Rockville, MD | Full-Time
Join a dynamic team advancing evidence-based treatment for addiction and PTSD.
Maryland Treatment Centers (MTC) is seeking a full-time ResearchScientist and Clinical Psychologist to support innovative addiction research within our Rockville treatment center. This role offers the chance to develop a research-oriented career in substance use disorder (SUD) and trauma treatment while working alongside a multidisciplinary clinical team.
What You'll Do:
· Coordinate a clinical trial for the treatment of PTSD taking place within a residential addiction treatment setting.
· Provide direct clinical services (Written Exposure Therapy for PTSD) as a study therapist on the project.
· Supervise research staff and assist with data collection and analysis.
· Collaborate with senior researchers on publications, grant development, and new studies.
· Mentor trainees and participate in extern supervision and teaching.
Why Join Us:
· Be part of a robust research division housed within a community treatment program
· Work in a supportive, collaborative, and mission-driven environment.
· Receive mentorship, professional development, and travel support for research dissemination.
· Grow into leadership roles in clinical research or program development.
What We're Looking For:
· PhD or PsyD in Clinical Psychology (or related field).
· Licensed or license-eligible in Maryland (supervision possible).
· Interest or experience in addiction and trauma research preferred.
· Masters-level clinicians with research curiosity encouraged to apply (e.g., LCPC, LCSW).
How much does a research scientist earn in Halfway, MD?
The average research scientist in Halfway, MD earns between $56,000 and $121,000 annually. This compares to the national average research scientist range of $58,000 to $137,000.
Average research scientist salary in Halfway, MD
$82,000
What are the biggest employers of Research Scientists in Halfway, MD?
The biggest employers of Research Scientists in Halfway, MD are: