Research Associate III - Computational Biomedicine
Research scientist job in San Diego, CA
Under general guidance, the Administrative Research Associate III works closely with PI, providing technical and/or administrative support in large or multi-project oriented labs. May be requested by PI to take on specific supervisory activities, and provide administrative leadership, and/or technical expertise. May develop hypothesis and assist in planning steps for the investigative process. Will review and remain current on literature as it relates to clinical/research study. Coordinates all lab and/or clinical activities, including but not limited to, budgetary/financial compliance, preparation of grant proposals, and creating independent presentations. Not responsible for generating grant funds.
Primary Duties and Responsibilities
Provides miscellaneous clinical/research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.).
Organizes clinical/research trials in conjunction with the Principal Investigator and sponsor and/or funding source.
Monitors and ensures compliance with safety standards and procedures
Analyzes data and prepares scientific findings for publication as author or co-author.
May make independent presentations
May provide system administration and maintenance for the local workstation network.
Leads and trains Research Lab Assistants, Research Fellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities.
Orients new Research Fellows and/or Research Scientists to day-to-day lab operations and procedures.
Qualifications
Educational Requirements:
Requires a bachelor's degree in molecular biology, genetics, biochemistry or related science field.
Experience:
Two (2) years minimum experience in research specialty required
Three (3) years of research lab experience required
Department Specific Experience:
Strong aseptic technique
Molecular laboratory techniques such as RNA isolation, DNA synthesis, PCR, Western blotting, Gel Electrophoresis, and cell culture.
Experienced in handling and working with small laboratory animals, mouse is preferred.
Analytical and problem-solving skills
Good written and verbal communication
Ability to work independently and as part of a team
Req ID : 12226
Working Title : Research Associate III - Computational Biomedicine
Department : Computational Biomedicine
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Research Studies/ Clin Trial
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $53,518 - $90,979
Associate Scientist
Research scientist job in San Diego, CA
Representative responsibilities will include, but not necessarily be limited to, the following:
Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays.
Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations.
Author and review QC analytical SOPs, protocols, and reports as needed
Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports
Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures.
Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated
Skills:
Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products.
Education:
BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience
Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role
Experience in an FDA-regulated environment
Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic
Excellent organizational and communication skills
Experience with JMP statistical software a plus.
Oncology Late-Stage Clinical Scientist (Director, Non MD)
Research scientist job in San Diego, CA
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You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio.
KEY RESPONSIBILITIES
Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment.
Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program.
Responsible for scientific oversight, data integrity and quality of the clinical trial(s).
Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy.
Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate.
Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders.
In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s).
Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; leads or actively participates in portfolio- and enterprise level workgroups aimed at optimizing PFE clinical development procedures; may be a subject matter expert or business process owner for a relevant SOP or procedure.
MINIMUM QUALIFICATIONS
PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, OR
MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO OR
BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO
Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval
Excellent knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations
Extensive understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance
Experience working on large data sets
Proficiency with Microsoft Office and relevant scientific software
Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery
Experience leveraging a variety of communication tools and techniques to communicate results
Experience solving problems collaboratively and handling conflict constructively
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations
Experience working proactively and independently, organizing tasks, time and priorities of self and others
Experience building partnerships across the company to achieve the needs of the program
PREFERRED QUALIFICATIONS
Experience in Hematology Oncology
COMPETENCIES FOR SUCCESS
Demonstrates passion for helping patients with cancer and for the science of oncology
Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned
Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities
Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes
Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies
Demonstrates foresight and judgment to make complex decisions
Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes
Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development
Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. both as a leader and a key contributor
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Medical
AI Machine Learning Scientist
Research scientist job in San Diego, CA
, please email **********************
We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines.
RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions.
The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery.
Duties and Responsibilities:
Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform.
Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery.
Monitor and evaluate the performance of AI/ML models and drug discovery solutions.
Utilize software engineering best practices to develop complex AI applications at scale.
Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML.
Proactively scope and deploy novel computational methods and digital technologies.
Education and/or Experience:
Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field.
Expertise in deep learning and machine learning.
Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow)
Knowledge, Skills, and Abilities:
Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience.
Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods.
Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs).
Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins.
Fluency in scientific programming and tool development with Python, R, or equivalents.
Proficiency in C++ or Java is a plus.
Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications.
Experience with software development good practices, including code versioning, documentation, and testing.
Experience with cloud computing.
Creative, open-minded, and passionate about scientific research.
Demonstrated ability to thrive in a team environment.
Strong interpersonal, collaborative, organizational, and presentation skills.
Understanding of RNA therapeutic modality discovery and development.
No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California.
Supervisory Responsibilities:
This position does not currently have direct reports.
Perks and Benefits:
Generous employer-paid healthcare for Medical, Dental, and Vision.
100% Employer Paid Life, STD and LTD
401(k) Employer Match
Generous Vacation and Sick Leave
13 Holidays
Closed over the Christmas and New Year Holiday Break
Research Associate I
Research scientist job in San Diego, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
As a Research Associate you will support the development of novel microfluidic platforms. You will be part of a multidisciplinary team solving complex problems, working on integration issues and investigating new research areas. Candidates that are engineering with a foundation in biology are better suited for this role vs. pure biologists.
Hands-on testing, integration and optimization of microfluidic systems including fluidics, hardware, firmware, software, and chemistry/reagents Quickly fabricate and test prototyped microfluidic systems Conduct system level testing, assay testing, image analysis Translate benchtop assays to prototype microfluidic systems Use standard lab instrumentation: fluorescence plate readers, fluorescence microscopes, thermocyclers, bioanalyzers, DNA sequencers, syringe pumps Develop and implement experimental test plans Record and analyze complex data sets Develop creative solutions to troubleshoot issues Willingness to be hands-on Share and record experimental results for an audience with broad technical backgrounds at technical meetings
Qualifications
Skills:
Microfluidics Experience with prototyping microfluidic systems: 3D printers, CO2 laser, laser ablation, profilometry Demonstrated ability to understand and successfully work across multiple disciplines including engineering, biology, and software is highly desired
1-2 years of experience in a clean room
1-2 years of experience in a lab environment with wet biology or chemistry experience
1-2 years of experience in product development is highly desired Experience in a BSL-2 lab is a plus Experience with sequencing, library prep and PCR is highly desired Organized and detail oriented Clear communicator and a team player Multidisciplinary approach to problem solving A desire to be part of face paced dynamic environment
Education and Experience
Undergraduate degree in Mechanical Engineering, Bioengineering, Chemical Engineering, Analytical Chemistry, or Physics
Additional Information
Vishnu Kumar
Technical Recruiter
Artech Information Systems LLC
360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960
Office: *************** | Fax: ************
Research Associate I
Research scientist job in San Diego, CA
Job Title: Research Associate I Duration: 18+ Months Job Description: We are seeking a highly motivated contract Research Associate with strong interpersonal communication skills to conduct in vivo studies in mice in our In-Iivo Pharmacology group at La Jolla to support oncology research.
RESPONSIBILITIES:
• Support in vivo experiments
• Flexible working hours including late shift, weekends and holidays
• Strong interpersonal communication skills and team player.
TECHNICAL SKILLS:
• Proficient in handling mice.
• Proficient in administering compounds via various routes (PO, IV, IP, SC).
• Blood collection (via cheek bleed, RO, intra-cardiac).
• Necropsy, collection of various tissue samples for biomarker analysis.
• Experience with tumor cell subcutaneous implantation in mice and live animal surgery is a plus.
• Proficient in data collection/documentation, either in electronic or hardcopy forms.
Qualifications
What is the minimum education experience required?:
ALAT/ALATg, or BS degree in a life science with minimum 1-2 years of hands on laboratory experience in small animal experimentation.
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• This position requires flexible working hours: A regular 5 day work week will include and require: late shift and include Sat/Sun and holidays. BID dosing schedules are central to this position.
• Lift animal cages.
• Handle hazardous materials and work in animal facility which will require additional medical testing and/or apparatus fitting for OSHA compliance.
Thank You !
Additional Information
All your information will be kept confidential according to EEO guidelines.
R&D Scientist
Research scientist job in San Diego, CA
Job Description
Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation.
The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability.
**This is a hybrid position must onsite at least 3 days a week in San Diego, CA.
Key Responsibilities
Develop and optimize analytical and testing methods to support ingredient characterization and functional performance.
Design and validate finished product specifications related to nutritional and bioactive properties.
Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality.
Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification.
Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones.
Provide scientific input and data to support patent filings and intellectual property development.
Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams.
Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline.
Qualifications
Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field.
5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry.
Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred.
Proven experience collaborating with external laboratories or CROs.
Strong technical writing, data interpretation, and presentation skills.
Ability to manage multiple complex projects in a fast-paced, dynamic environment.
Creative, detail-oriented, and motivated by scientific discovery and product excellence.
This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you.
Compensation: $120,000 - $140,000plus benefits
If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose.
Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
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Associate Scientist I, Discovery Chemistry (Bioconjugation)
Research scientist job in San Diego, CA
Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry.
Responsibilities
* Maintain a well-documented laboratory notebook
* Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
* Perform tasks across projects
* Manage time effectively to meet deadlines
* Adhere to safe laboratory practices
* Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines
Requirements:
* B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry
* 0-3 years of experience working in a chemistry laboratory
* Experience with a wide range of analytical techniques, especially HPLC
* Ability to quickly learn new procedures and techniques
Preferred:
* Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting
* Experience with solid-phase peptide synthesis (automated and/or manual)
* Prior experience in a pharmaceutical or biotechnology environment
Auto-ApplyR&D Scientist
Research scientist job in Carlsbad, CA
R&D Scientist - NGS Technology and Applications
title depends on qualification and experience)
Universal Sequencing Technology (UST) Corporation (universalsequencing.com), a leading NGS technology company engaged in long range/long read sequencing technology and single cell sequencing technology development, headquartered in greater Boston with a branch in San Diego, is looking for an outstanding R&D scientist to join our NGS technology and product development team in San Diego. This position is a unique opportunity to work on a cutting edge NGS library technology which enables many previously unachievable applications, especially in the clinical space.
This person will work closely with a team of molecular biologists, bioinformatics scientists, instrument engineers and manufacturing specialists to develop a revolutionary single cell sequencing technology. He/she will play a key role in the development and validation of the technology as well as the commercial launch of products. He/she will also interact with external collaborators and early access customers, and provide technical support.
The ideal candidate should have extensive cellular and molecular biology experience. He/she must have direct experience on cellular assay development and RNA manipulation; strong project management skills; ability to take initiative; effective verbal and written communication skills; and be an excellent team player. RNA-Seq, NGS library preparation, and sequencing data analysis skill under both Linux and Windows environment are desired; Molecular biology reagent kit development experience is a plus.
Key Responsibilities:
Lead NGS based single cell sequencing assay and reagent kit development
Establish product quality control assays for in-process & final product test and deliver well-characterized & robust processes to manufacture
Design and execute experiments, and analyze data independently
Support current product improvement and commercialization
Interact with collaborators and customers to promote UST technology and product
Qualifications:
Ph.D. in molecular biology, cellular biology, biochemistry or related fields (M.Sc. with exceptional experience will be considered)
Minimum 3-years of cellular assay development and gene expression profiling experience
Single cell sequencing library preparation, immune repertoire sequencing or early tumor detection experience is a plus
Product development experience is preferred
Auto-ApplyResearch Associate
Research scientist job in San Diego, CA
Job Description
Pave Talent is excited to present an incredible opportunity for a Research Associate to join a cutting-edge stem cell research team in San Diego, CA!
Scientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplyScientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
* Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
* Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
* Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
* Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
* Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
* Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
* Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
* Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
* Proven hands-on experience with multiple mammalian expression platforms is required
* Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
* Experience with therapeutic antibody developability assessment is highly desirable
* Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
* Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
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Auto-ApplyResearch Biologist
Research scientist job in San Diego, CA
Research Biologist needs 2-3 years experience
Research Biologist requires:
Degree in biology
Laboratory equipment and procedures.
MS Office
Lab techniques
Research
Biochemistry
Cell biology
Experience in running biochemical and immunological assays.
Research Biologist duties:
Ø Conduct experiments to identify and validate drug targets.
Ø Support assay design, optimization, validation, and data analyses.
Ø Design and execute molecular and cell biology experiments.
Ø Troubleshoot and analyze complex data in support of drug discovery projects.
Ø Presentation of results and conclusions both orally and written.
Scientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
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Auto-ApplyIn Vivo Research Associate II, Large Animal
Research scientist job in San Diego, CA
Job Description
In Vivo Research Associate II
FLSA Status: Non-Exempt
Pay Rate: $28 - $32 /hr
Pharmaron (San Diego) is seeking to hire an outstanding candidate to join our Medical Device department at the Research Associate II level. The Research Associate will play an important role by supporting in vivo studies to test medical devices. This position requires a broad knowledge of animal anatomy, physiology, and biochemistry to help develop and support in vivo models to screen therapeutics and devices being developed for various indications.
Responsibilities:
Experience in the administration of test substances by various basic methods (i.e., oral gavage, SQ, IV, dermal, etc.)
Manage and observe animals for general health and overall wellbeing.
Experience in the collection of biological specimens (i.e., blood from appropriate vessels from all species of laboratory animals at the site)
Able to perform study related activities in compliance with Good Laboratory Practice Regulations (GLPs), study protocols, and company policies and Standard Operating Procedures (SOPs)
Review documentation to ensure functions performed meet quality control requirements.
Handle, restrain, and provide care for all species of laboratory animals at the site.
Perform study preparation activities, including collection tube labeling and room setup.
Perform catheter placements in large animals.
Perform surgical procedure: intubation, anesthesia, pain recognition and analgesia.
Monitor animals under anesthesia and during post-operating monitoring and recovery.
Perform biopsies and skin excisions.
Perform necropsies and tissue collection.
Interface with different teams, including study director, principal investigator, QC/QA, and Account Managers/Sales.
Maintain accurate records in various internal databases.
Support internal research projects to optimize service offerings. Perform aseptic techniques.
Perform other duties as directed by management.
What We're Looking For:
We're seeking individuals who have strong communication skills with attention to detail who thrive in fast-paced environments.
Associates degree (preferred) in veterinary technology with 3 years relevant experience.
BS with at least 2 years relevant experience.
Education level requirements could be amended based on relevant years of experience.
Certification as a registered veterinarian technician (RVT) is a plus.
Background in lab animal (in vivo) research is a must.
Working knowledge of preclinical techniques and modalities will be a plus.
Position requires good communication skills and attention to detail.
Strong work ethic, self-motivation, and ability to adapt to a dynamic team environment.
Why Pharmaron?
Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.
Collaborative Culture: You'll thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.
Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
Insurance including Medical, Dental & Vision with significant employer contributions
Employer-funded Health Reimbursement Account
Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
401k plan with generous employer match
Access to an Employee Assistance Program
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
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Pharma Molecular Biologist
Research scientist job in San Diego, CA
Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to build lasting partnerships that enable the life sciences industry to accelerate discovery and innovation in research and manufacturing. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.
Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. We aim to recruit the best people who stand out among their peers and embody our Core Values:
Client Focused: We only succeed when our clients succeed.
Outstanding: We deliver meticulous results through outstanding performance.
Good: We act ethically and morally.
Employee-Centric: We honor and support our employees.
Nimble: We are prepared to adapt in an ever-changing industry.
Team-Oriented: We collaborate with each other and with our clients.
We currently have a role available for a Protein Biochemist to join our San Diego based team.
Job duties include, but are not limited to, the following:
DNA prep/isolation, SDS-PAGE, ELISA, DNA sequencing and analysis.
Strong molecular biology experience is highly desirable.
Mammalian tissue culture
Prior cell culture experience is preferred.
Prepare and maintain reagents, buffers, and other laboratory supplies.
Must have previous experience in liquid handling.
Work closely with team members to ensure timely and accurate completion of projects.
Ensure compliance with all safety and regulatory requirements in the laboratory.
This position is a hands-on lab-based role
Job requirements include, but are not limited to:
BS/MS degree in Biological Sciences (or related field) and 6 months - 1 year laboratory experience in either industry is required.
Team player mentality with strong written and verbal communication skills. Will be required to work collaboratively with cross-functional teams including structural biology, molecular biology, biochemistry, and biophysics.
The ideal candidate will be organized, comfortable with multi-tasking, enthusiastic, self-motivated and details oriented, with the skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.
This job posting will close by February 28th 2026 or when candidates are identified, whichever comes first.
Research Associate I - Sati Lab - Department of Neurology
Research scientist job in San Diego, CA
Are you a hardworking and dedicated research professional interested in being part of breakthrough Research?
When you join Cedars-Sinai, you become part of a team that is at the forefront of medical advancements and life-saving medical and scientific breakthroughs. Cedars-Sinai is one of the leading institutes for driven research funding from the National Institutes of Health.
Principal Investigator, Pascal Sati, PhD is searching for a Research Associate I to join the team!
The Sati Laboratory focuses on the development of novel imaging biomarkers, magnetic resonance imaging (MRI) techniques, and artificial intelligence (AI) methods that strive to improve the clinical care offered to those impacted by neurological disorders. To learn more, please visit the Sati Research Lab.
Working under direct supervision, the Research Associate I performs a variety of computational procedures to support the objectives of the laboratory research projects in Neuroimaging. Assists in laboratory activities, including maintenance of imaging pipelines and computer equipment. Keeps accurate and detailed records of imaging dataset, pipelines and results. The incumbent will be able to perform routine image processing and analysis of neuroimaging dataset. This position does not have supervisory responsibilities.
Primary Duties and Responsibilities:
Performs a variety of routine laboratory tasks and procedures related to Neuroimaging.
Assists in the operation of specialized computing equipment.
Performs lab maintenance duties, including data backup and software upgrades.
Assists students and fellows at the laboratory.
Maintains lab computer equipment and related records.
Observes and aligns with safety standards and procedures.
Department-Specific Duties:
Performs image processing, image segmentation and image analysis of neuroimaging dataset.
Implements and optimizes image processing algorithms used in neuroimaging research.
Qualifications
Education:
Bachelor's degree in a Science related field, required.
Experience and Skills:
Research laboratory experience is preferred.
Understanding of general research objectives.
Solid understanding of programming languages, neuroimaging tools, computing environments, database management, personal and server computers, and statistical platforms.
Experience with routine imaging processing procedures for neuroimaging research.
Must possess digital literacy to include, but not limited to, Unix/Linux systems, Python, Matlab, Bash, R, REDCap, SPSS and Excel.
About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
Req ID : 13460
Working Title : Research Associate I - Sati Lab - Department of Neurology
Department : Neurology
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Research Studies/ Clin Trial
Overtime Status : NONEXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $19.50 - $29.87
Oncology Late Stage Clinical Scientist (Senior Manager, Non MD)
Research scientist job in San Diego, CA
You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate . Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams , governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s , analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings , seeks opportunities to further improve quality and efficiency of clinical procedures; MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 2 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 5 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 7 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval. Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance. Experience working on large data sets. Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience building partnerships across the company to achieve the needs of the program. PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology. Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned. Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities. Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes. Leverages knowledge and support from others related to overall objectives , strategy, critical issues, and policies. Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes. Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies . Work Location Assignment: This is a Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Research Biologist
Research scientist job in San Diego, CA
Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry
Research Biologist requires:
Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry
Experience in running biochemical and immunological assays.
Highly motivated and agile biochemist
Research Biologist duties:
Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies
Perform basic tasks to support tissue culture and maintenance of immune competent cell lines
Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.)
Work with a cross-disciplinary team for data analysis
Independently execute experiments, analyze, interpret and present experimental data
Associate Scientist I, Discovery Chemistry (Bioconjugation)
Research scientist job in San Diego, CA
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry.
Responsibilities
Maintain a well-documented laboratory notebook
Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
Perform tasks across projects
Manage time effectively to meet deadlines
Adhere to safe laboratory practices
Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines
Requirements:
B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry
0-3 years of experience working in a chemistry laboratory
Experience with a wide range of analytical techniques, especially HPLC
Ability to quickly learn new procedures and techniques
Preferred:
Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting
Experience with solid-phase peptide synthesis (automated and/or manual)
Prior experience in a pharmaceutical or biotechnology environment
California pay range $60,000-$80,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
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