Senior scientist jobs in Bartlett, TN

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Our client is a public and rapidly growing diagnostics company that is looking to expand their Quality team in Memphis TN. They are willing to assist with relocation. Relocation assistance is provided! Excellent benefits, competitive salary, and stock options. Job Description Under direct supervision, responsible for design, performance and interpretation of experiments in support of the company's product development. Responsibilities: Responsible for the design and conduct of experiments as defined by work streams in accordance with the company's Quality System and to regulatory standards Ensures that work is completed to agreed timelines, communicating delays or issues to supervisor in timely manner Prioritizes workload to insure key objectives are met on time May supervise the work of a junior member of staff Presents data at internal and external meetings Ensures that conclusions in written reports reflect the data presented and reports are of the highest quality When required, operate as a scientist in support of running Laboratories, ensuring that the Quality Management System, including ISO 9001:2008, ISO 13485:2003, CLIA and CAP, is adhered to at all times and in all aspects of the job Perform other duties in departments on an occasional basis to meet critical company objectives Follows all company safety policies & other safety precautions within work area Regular attendance and timeliness is essential Qualifications BS or MS Degree in life sciences, Higher preferred Experience with cell culture techniques imperative Hands-on experience with flow cytometry and PCR techniques Demonstrated understanding of the diagnostic and pharmaceutical industries Familiarity with Quality System concepts and requirements including GMP and ISO Working knowledge of ELISA and ELISPOT a distinct advantage Expert at analyzing data Must be proficient in MS Office Additional InformationAll your information will be kept confidential according to EEO guidelines.

**Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. **Your Impact** + Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. + Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. + Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. + Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. + Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. **Minimum Qualifications:** + PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. + Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. + Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) + Experience translating research ideas into production systems. **Preferred Qualifications:** + Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. + Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. + Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. + Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. + Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. + MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. + Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. **Why Cisco?** At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Simply put - we power the future. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. **Why Cisco?** At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. **Message to applicants applying to work in the U.S. and/or Canada:** The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: + 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees + 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco + Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees + Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) + 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next + Additional paid time away may be requested to deal with critical or emergency issues for family members + Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: + .75% of incentive target for each 1% of revenue attainment up to 50% of quota; + 1.5% of incentive target for each 1% of attainment between 50% and 75%; + 1% of incentive target for each 1% of attainment between 75% and 100%; and + Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. ** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements. Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis. Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.

Job Description Food Scientist The Food Scientist is responsible for high level Project Management of key accounts, displaying leadership capabilities, while exhibiting product development expertise. We are open to candidates at various experience levels, from early-career food scientists, to seasoned professionals Essential Functions Meet the requirements of a Senior Scientist I Perform high level project management Develop mastery of customer's products and processes Mentor entry level scientist and interns when applicable Demonstrate significant innovation and improvement in product development and processes Respond and adapt to change quickly Identify root cause of a problem and implement corrective action Conduct situation analysis and troubleshoot Recognize and incorporate industry advances and technology Display superior knowledge of ingredients Design and implement all technical aspects of projects to ensure that all projects proceed according to plan Apply delegation skills when appropriate Perform other duties or special projects as needed. Qualifications Requires a Bachelor's Degree in Food Science, Culinary Science, Biology, Chemistry or related field. Minimum of eight years related experience and/or training. Strong communication, interpersonal skills and general knowledge in MS Office, AS400 and Lotus Notes. Work Environment General office setting. Periodic exposure to: (1) loud environment, (2) airborne particles with stronger odors associated with spicy food ingredients, (3) cold, hot, wet and humid conditions, (4) walking and standing on concrete, (5) climbing steps, ladders, (6) standing on elevated surfaces. Benefits: Medical Insurance Prescription Drug Plan Dental/Vision Insurance Employee Incentive Plan Flexible Spending Account Cash Accumulation Plan-401K Life/AD&D Insurance Short- Term/Long-Term Disability Vacation Plan Paid Holidays Employee Assistance Program Adoption Assistance Program Tuition Reimbursement Maternity/Paternity Leave Pet Insurance Salary: $90,000 - $135,000

Clinical Research Investigator DM Clinical Research, the largest privately-owned research management organization in the Houston area and one of the top 50 in the country, is looking for an Investigator for our sites in Memphis, TN. This individual will conduct all clinical trials (studies) according to ICH, GCP, local regulations, study protocols, and company processes. Responsibilities Ensures the medical well-being and safety of the participants through the safe performance and execution of the studies. Assists in maintaining clinical oversight and quality on the studies registered on and delivers on study targets, thereby contributing to the commercial success of the site. Reviews enrollment progress, pre-screening and screening success rates, screen failure rates, safety, and retention of participants. Interprets protocols and IB and participates in initiatives to strategize for patient recruitment. Carries out clinical evaluation and assessment of participants to ensure eligible participants are enrolled onto studies. Ensures and protects the welfare and safety of participants through ethical conduct. Fulfills and comply with all medical duties as per protocol, SOP/COP and ICH GCP and local regulations. Exercises meticulous attention to detail in documentation and patient care. Requirements Medical License (MD, DO) At least 2 years of experience as a Clinical Research Investigator. Spanish Bilingual a plus.

We are seeking a highly skilled and motivated Senior Scientist to direct daily laboratory operations and spearhead method development for high-throughput screening that will uncover the therapeutic potential of intrinsically disordered regions. This is an exciting opportunity for an experienced molecular biologist to take a leadership role in a collaborative academic environment, supporting a large-scale screening project and pioneering new cell perturbation methodologies. The postholder will oversee the day-to-day operation of the experimental arm of the research group and lead the development of innovative experimental pipelines to advance lentiviral-based screening technologies across diverse biological systems. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Drive the development of innovative experimental strategies to expand and enhance the existing screening capabilities of the group. Manage laboratory operations by coordinating daily activities, maintaining and troubleshooting equipment, and ensuring adherence to institutional regulatory requirements. Support the design, optimization, and implementation of pooled lentiviral screening workflows, including peptide inhibitor and base/prime editing platforms. Develop and maintain standard operating procedures (SOPs), ensure quality control, and promote best laboratory practices. Supervise and mentor postdoctoral researchers, research assistants, and students involved in screening projects. Engage in collaborative research and contribute to publications, grant proposals, and presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Extensive experience in CRISPR-based genome engineering in mammalian cell systems. Demonstrated expertise in the design, production, and application of lentiviral libraries for large-scale screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Demonstrated ability to manage laboratory operations, including supervision and training of staff or students. Excellent organizational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Experience with base or prime editing systems. Familiarity with large-scale data generation and interpretation in screening contexts. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The postholder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterization of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localization. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required Minimum Experience: Ten (10) years relevant work experience is required with a Bachelor's degree. Eight (8) years of relevant work experience is required with a Master's degree. Five (5) years of relevant work experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Scientist (Pooled Lentiviral Screening & Method Development). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Simply put - we power the future. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description They must have protein purification experience including non-labeled proteins and They are NOT looking for candidates with molecular/PCR/gene cloning, etc. Summary Description: Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. Duties: o Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). o Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. o Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. o Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. o Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. o Train Production Technicians in upstream and downstream manufacturing processes. o Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. o Write and execute validation protocols for new and existing manufacturing processes. o Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications Required Qualifications: o Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. o Extensive knowledge and hands on experience of protein purification and characterization. o Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. o Hands on experience with in vitro cell culture and recombinant protein fermentation o Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. o Proven experience with process scale-up procedures. o Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). o Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. Requirements (Physical, Mental, Environmental Demands): o Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. o Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. o Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. o Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. o Must be able to lift up to 30lbs. multiple times daily. o Must be able to travel by air/car to other locations of MBI as needed. o May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Manisha Jathar 732 429 1850

We are seeking a highly motivated and service-oriented Scientist with expertise in cryo-Electron Tomography (cryo-ET) to join our team. This role supports St. Jude's expanding cryo-ET capabilities and provides direct assistance to a diverse community of researchers using state-of-the-art cryo-EM technologies to advance discoveries in pediatric cancer, infectious disease, and fundamental biology. As part of the cryo EM/ET center, the successful candidate will play a central role in enabling end-to-end cryo-ET workflows ranging from specimen preparation and cryo-FIB milling to cryo-TEM data acquisition and preliminary analysis. The position is service-oriented, collaborative, and offers opportunities to participate in technology development projects, evaluate new methods, and contribute to the strategic growth of cryo-ET capabilities within St. Jude. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities Provide hands-on support for cryo-ET sample preparation, including plunge freezing, high-pressure freezing, cryo-CLEM workflows, cryo-FIB lamella preparation, and TEM screening Operate, maintain, and monitor high-end cryo-EM instrumentation (Titan Krios, Glacios, Arctica and Aquilos 2) to ensure optimal performance and maximize user access Train new and experienced users in cryo-ET techniques, microscope operation, and best-practice standards aligned with cryo EM/ET center's guidelines Work closely with researchers to design and execute tomography data-collection strategies that meet research goals Perform initial quality assessment of tilt-series data and assist users with reconstruction and early-stage data processing Participate in development and optimization of emerging cryo-ET workflows, protocols, and automation strategies Maintain accurate documentation related to user training, sample preparation sessions, instrument usage, and standard operating procedures Contribute to a safe, inclusive, and service-focused environment that reflects St. Jude's commitment to excellence and collaboration Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience for a Scientist Level: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Minimum Experience for a Senior Scientist Level: Ten (10) years relevant work experience is required with a Bachelor's degree. Eight (8) years of relevant work experience is required with a Master's degree. Five (5) years of relevant work experience is required with a PhD. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist or $104,000 - $186,160 per year for the role of Senior Scientist. Preferred Qualifications & Experience: PhD or equivalent degree in Structural Biology, Biophysics, Biochemistry or a related field Demonstrated experience with cryo-EM workflows, ideally including cryo-ET sample preparation, lamella milling, and tomography data acquisition Strong understanding of microscope alignment, image acquisition parameters, and cryo-EM instrumentation Hands-on experience with tilt-series acquisition, tomogram reconstruction, and subtomogram averaging pipelines (e.g., IMOD, Dynamo, RELION, M/Warp, EMAN2) Ability to troubleshoot complex workflows and assist users with technical challenges Excellent communication skills for working in a diverse, multi-disciplinary user environment Interest in technology development, workflow automation, or method optimization. The World's Best Stop at Nothing There's a reason St. Jude Children's Research Hospital is consistently ranked on Glassdoor's “Best Places to Work” list. Actually, there are more than 5,500 reasons. At our world-class pediatric research hospital, every one of our 5,500 professionals shares our commitment to making a difference in the lives of the children we serve. There's a unique bond when you are part of a team that will stop at nothing to advance the treatments and cures of pediatric catastrophic diseases. The result is a collaborative, positive environment where all employees, regardless of their role, receive the resources, support, and encouragement to advance and grow their careers. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Scientist or Senior Scientist Opportunity in the St Jude cryo EM/ET center. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description Job Position: Senior Manufacturing Technician or Senior Manufacturing Process Scientist Location: Memphis, TN Duration: Fulltime Permanent Relocation: Relocation Package is Provided Our Client is looking for Senior Manufacturing Process Scientist- With protein purification etc. experience…..!!!!! Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. SUMMARY & RESPONSIBILITIES: • Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). • Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. • Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. • Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. • Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. • Train Production Technicians in upstream and downstream manufacturing processes. • Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. • Write and execute validation protocols for new and existing manufacturing processes. • Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications QUALIFICATIONS AND SKILLS NEEDED: • Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. • Extensive knowledge and hands on experience of protein purification and characterization. • Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. • Hands on experience with in vitro cell culture and recombinant protein fermentation • Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. • Proven experience with process scale-up procedures. • Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). • Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. • MUST BE US CITIZEN or GREEN CARD holder only. Requirements (Physical, Mental, Environmental Demands): • Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. • Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. • Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. • Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. • Must be able to lift up to 30lbs. multiple times daily. • Must be able to travel by air/car to other locations of MBI as needed. • May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Regards Pooja Mishra Clinical Recruiter Integrated Resources, Inc. IT Life Sciences Allied Healthcare CRO Certified MBE |GSA - Schedule 66 I GSA - Schedule 621I Tel: 732 429 1636 (W) 732-549-2030 x 214 | (F) 732-549-5549 Gold Seal JCAHO Certified ™ for Health Care Staffing “INC 5000's FASTEST GROWING, PRIVATELY HELD COMPANIES” (8th Year in a Row)

Are you a driven scientist with a passion for advancing our understanding of childhood immune development? The Crawford Lab is seeking a Senior Scientist to lead and shape research into the mechanisms of pediatric immunity, leveraging cutting-edge technologies and multidisciplinary approaches. The Crawford Lab About the Opportunity This is a unique opportunity to join the ground level of a new endeavor in the Crawford Lab focused on the comprehensive characterization of the human immune system throughout childhood development. You will work closely with experts in next-generation, multi-omic assays and integrative computational analysis to unravel the complexities of immunity in health, disease, and treatment. This work will need expert knowledge of human immunology, which you will apply collaboratively to: Design panels of relevant immunological markers for immune phenotyping, biological perturbations, and health or disease states. Generate gold standard data to validate novel sequencing-based approaches. Test and validate novel, sequencing-based approaches to data generation Synthesize and interpret molecular underpinnings from population-level, multi-modal data from primary samples. The ideal candidate will have extensive bench experience, a keen attention to detail, and a history of first-author publications in immunology. Success in this position also requires: Excellent communication and organizational skills The ability to multi-task and collaborate effectively Comfort working in tandem with a culturally and scientifically diverse team to achieve shared research goals We're Especially Interested in Candidates With: Deep and current knowledge of immunology literature. Extensive expertise in human peripheral or mucosal immunology. Proven research experience in innate/adaptive immunity and host-pathogen interactions. Hands-on experience studying childhood immune system development. Technical proficiency in cell culture, multiparameter flow cytometry, biomarker discovery, and primary human sample analysis. Key Responsibilities Design, execute, and oversee experiments/projects independently under the direction of the PI. Develop and refine research protocols, techniques, and procedures Analyze, organize, and interpret complex datasets-including flow cytometry and omics data. Ensure data quality and integrity; prepare reports and summaries of experimental results. Present research findings internally and at external conferences; contribute to manuscripts as co-author or lead writer. Support and optimize lab operations: recommend equipment, troubleshoot instruments, and guide process improvements. Mentor and train junior scientists and lab staff in advanced immunology methods and analytical techniques. Contribute to ongoing and new research initiatives to achieve departmental and institutional goals. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Ten (10) years relevant work experience is required. Eight (8) years of relevant work experience is required with a Master's degree. Five (5) years of relevant work experience is required with a PhD. Why The Crawford Lab? Join a collaborative, innovative team at the forefront of childhood immunology research. Work with state-of-the-art instrumentation and contribute to discoveries that have real-world impact on pediatric health. Ready to help shape the future of childhood immunology? Submit your CV and a cover letter detailing your expertise in childhood immune systems, flow cytometry, and omics technologies. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Scientist - Human Systems Immunology (Crawford Lab). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

We are seeking a highly motivated and innovative Principal Scientist with specialized expertise in drug discovery to direct our Chemical Induced Proximity Center in the highly collaborative Department of Chemical Biology and Therapeutics. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. The incumbent will be responsible for driving strategic decisions throughout the various stages of the small molecule drug discovery process focusing on chemically induced proximity platforms. Experience with use of computational tools including Artificial Intelligence (AI) and Machine Learning (ML) in virtual screening, small molecule design and optimization is preferred. Set up the chemistry strategy for projects and advance drug discovery programs by collaboratively interacting cross-functionally within departmental collaborative centers and various departments at the institution. Lead and manage a team of scientists and large-scale, multidisciplinary projects through proactive research collaboration, and provide direction in specific area of expertise. Contribute to recruiting and growing the team, guiding and mentoring junior staff. Stay at the forefront of induced proximity platforms, including but not limited to PROTACs, molecular glues, and other bifunctional or allosteric modulators. Evaluate new technologies, chemical tools, and screening platforms that can accelerate the development of proximity-based therapeutics. Design and optimize focused chemical libraries to identify hits, leads, and drug candidates that induce selective protein interactions and cellular phenotypic changes. Maintain collaborative partnerships while ensuring recognition on collaborating publications and patents. Lead and manage a number of contract research organizations (CRO) and external chemistry partners across the globe. Oversee structure-activity relationship (SAR) studies to enhance potency, selectivity, and drug-like properties of candidate molecules. Lead efforts to improve the pharmacokinetic, pharmacodynamic, and toxicological profiles of compounds in collaboration with ADMET and DMPK teams. Serve as functional expert in due diligences for assets in-licensing and discovery partnerships. Responsible for leading publication efforts in high-impact scientific journals. Experience in drug discovery in Pharma/Biotech industry highly preferred. Experience with computational design or AI/ML preferred. PhD with management experience preferred. This is a senior leadership role with a focus on advancing cutting-edge drug discovery programs for childhood catastrophic diseases using the latest approaches in proximity-based targeting. Specifically, based on the mechanistic basis of disease, our goal is to develop unique chemical approaches (protein degraders, synthetic gene regulators and/or functional effectors) to degrade or manipulate targets relevant to pediatric oncology, neurodegenerative disorders, and sickle cell disease. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. PhD preferred. Minimum Experience: Fifteen (15) years of relevant work experience is required with a Bachelor's degree. Thirteen (13) years of relevant work experience is required with a Master's degree. Ten (10) years or relevant work experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal Scientist in Chemical Induced Proximity. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Directs, initiates and executes research strategies in partnership with Principal Investigator. Designs and conducts studies to investigate specific basic science or clinical research questions within field of expertise. Focuses on one or more specific scientific endeavors of the laboratory. Develops new experimental procedures and publishes research results. Job Responsibilities: Initiates and executes research strategies in partnership with the PI or more senior scientist. Develops new research protocols, techniques and procedures. Identifies emerging scientific and technical trends and advances with possible impact on laboratory research Identifies experimental data pertinent to the analysis problem. Processes, organizes and summarizes data, reporting these experimental results. Monitors quality and integrity of recorded information and data. Ensures data collection and entry methods meet quality standards. Interprets data as it relates to research problem. Generates hypotheses to predict future implications based on the critical evaluation of these data. May publish as first author in journals within discipline. Participates in manuscript peer review process as a formal reviewer where required. Presents research both internally and externally to multi-disciplinary audiences. Provides lab operation support and makes recommendations regarding equipment use and maintenance, supplies, etc. Troubleshoots instrument and equipment issues. Provides input into lab operation processes and procedures. Recommends equipment acquisition and decommissioning. Anticipates laboratory operational and capital needs and promotes standards of safety. Provides instruction and guidance to junior level staff and trains as needed. Maintains regular and predictable attendance. Performs other related duties as assigned in order to meet the goals of the department and the institution. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required Minimum Experience: Twelve (12) years of relevant work experience is required Ten (10) years of relevant experience is required with a Master's degree Seven (7) years of relevant work experience is required with a PhD Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $125,840 - $238,160 per year for the role of Lead-Scientist for Nanobody Core. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The Lead-Bioinformatics Research Scientist takes a lead role in data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Working independently, provides bioinformatics analysis for investigators and communicates analytical process and results. A Lead Bioinformatic Research Scientist position is available in the lab of Dr. Jian Xu at Department of Pathology and Center of Excellence for Leukemia Studies (CELS) at St. Jude Children's Research Hospital to study the genomic and/or metabolic mechanisms controlling stem cell development and blood cancers. Our lab uses cutting-edge genomics, metabolomics and bioinformatics approaches in a multi-disciplinary and collaborative team setting. Our recent studies include the development of the CRISPR CAPTURE approach ( Cell 170:1028), the analysis of rewired BCAA metabolism ( Cancer Discovery 9:1228), the role of pathogenic non-coding variants ( Cancer Discovery 10:724), retrotransposon silencing ( Nature Genetics 53:672), therapy resistance in hematologic malignancies ( Cancer Discovery 13:170), and metabolic rewiring in erythropoiesis ( Science 386:eadh9215). The main responsibilities will be developing and implementing bioinformatic methodologies for integrative genomic and metabolomic studies of childhood cancers; overseeing operations related to genomic and metabolomic data processing and analysis within the Advanced Technology & Genomics (ATG) core, including software pipelines for short-read and long-read-based genome sequencing, single-cell genomics, high throughput metabolomic profiling, and stable isotope tracing; managing databases; and providing bioinformatic support and services to other lab members and St. Jude researchers. Candidates must hold a MS or PhD degree with a strong background and expertise in genomics, computational biology, metabolism research, and/or cancer biology. The ideal candidate will exhibit independence, flexibility and creativity with a record of scientific productivity. Previous experience in single-cell genomics, computational biology, and/or hematology-oncology is strongly preferred. Interested individuals should upload a CV, a short summary of research interest and experience, and a list of three references. Job Responsibilities: Lead data analysis and deliver high-quality results by formulating advanced and/or new analytical approaches with the available data/ to address challenging data analysis questions. Deliver data files, and document the analytical process. Participate in manuscript preparation at project's conclusion. Establish and document protocols or best practices for common research tasks. Recommend ideas to automate or improve existing analysis methods and implement the improvement. Evaluate and test new methods and technologies. Develop reusable code and pipeline. Participate in redistribution and education of novel methods to research community when required. Lead and participate in the department's developmental projects and interdepartmental team projects. Act as a project manager when required. Perform other duties as assigned to meet the goals and objectives of the department and institution. Maintains regular and predictable attendance. Minimum Education and/or Training: Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master's degree or PhD preferred. Minimum Experience: Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $125,840 - $238,160 per year for the role of Lead-Bioinformatics Research Scientist. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Join the Zhou lab ProteinPaint team (************************************** to contribute to the development of an open-source platform for biomedical data visualization, analysis and sharing. The ProteinPaint began as a cancer mutation visualization tool (******************************************* and is now an umbrella platform spanning GenomePaint (******************************************* Neuro-Oncology portal (******************************************* Survivorship Portal (******************************************* NCI Genomic Data Commons (******************************* paper in preparation), and ASH HematOmics Program (*************************************** paper in revision). A portfolio of the software features are showcased at ********************************* Our software development focuses on multi-data-modality support, interoperability for data analysis, accountability with scientific rigor, and ease of access through AI chatbot. Along with continuous efforts to harden software features, ProteinPaint aims to support molecular and clinical data integration needs in cutting edge research. Fields of application include cancer genomics, single-cell omics, oncology, pharmacogenomics, population science, and public health. The applicant should be dedicating to a career of software development in genomics and general biomedical research. PhD in cancer, bioinformatics or relevant biological sciences is required. Proficiency in full-stack web development is required, including Linux, JavaScript, Node.js, R, Python, Rust, SQL and AI, along with knowledge in software testing, DevOps and Continuous Integration. While on the team, the new hire will work alongside other developers and PhD scientists and contribute to ongoing projects and have the opportunity to lead high-profile projects and give presentations or author scientific papers. Job Responsibilities: Lead computationally focused scientific research projects with moderate supervision from their PI. Provide inputs regarding analytical approaches, set up analyses, and can develop new computational research methods with input from PI. Identify, process, organize, summarize, review, and report relevant data. Draft a manuscript and work through the submission and review process with input from the PI, as directed. Instruct and provide guidance to other staff in basic computational research techniques and procedures. (In the case of recent Ph.D. graduates, this position can be considered equivalent to a mentored postdoctoral position.) Perform other duties as assigned to meet the goals and objectives of the department and institution. Maintains regular and predictable attendance. Minimum Education and/or Training: Bachelor's degree in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field required. Master's degree or PhD preferred. Minimum Experience: Minimum Requirement: Bachelor's degree and 6+ years of relevant experience. Experience Exception: Master's degree and 4+ years of relevant experience (OR) PhD with no experience. Rough criteria for this position based on publication output: 1-2 first author papers IF >5 (or equivalent contribution to other research outputs). Prior experience in computational research techniques preferred. Experience in project coordination, maintenance, and other research support activities preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Computational Research Scientist. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

We are seeking a highly motivated and talented scientist to join our team and lead cutting-edge research exploring the therapeutic potential of intrinsically disordered regions. This project will harness pooled lentiviral screening platforms for base/prime editing mutagenesis to systematically perturb key molecular interactions. It offers an exciting opportunity to apply innovative high-throughput technologies to uncover new regulatory mechanisms and identify novel therapeutic targets. The successful candidate will play a central role in developing and implementing advanced lentiviral-based screening pipelines across diverse biological systems, working at the interface of molecular biology, genomics, and translational discovery. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Design, optimize, and execute pooled lentiviral screening workflows for large-scale base/prime editing mutagenesis. Collaborate closely with bioinformaticians and project investigators to ensure robust experimental design, data acquisition, and analysis. Drive the development of innovative experimental strategies to expand and enhance existing screening capabilities. Contribute to collaborative research outputs, including publications and conference presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Demonstrated expertise in the design, production, and application of lentiviral vectors for genetic manipulation and screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Excellent organisational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Extensive experience in CRISPR-based genome engineering in mammalian cell systems. Demonstrated expertise in the design, production, and application of lentiviral libraries for large-scale screening. Experience with base or prime editing systems. Familiarity with large-scale data generation and interpretation in screening contexts. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The post-holder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterisation of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localisation. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist (Pooled Lentiviral Base Editing Screening). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Join Our Team! The Center of Excellence for Pediatric Immuno-Oncology (CEPIO) is seeking an experienced Scientist to manage the Center's immuno-oncology preclinical murine modeling core. CEPIO serves as the central hub to advance and coordinate cross-disciplinary studies in immuno-oncology across St. Jude basic and clinical Departments, Cores, and Centers. The successful candidate is expected to have significant prior experience in developing and standardizing preclinical murine models to support target discovery, validation, and functional testing, including the generation of new genetically engineered mouse models (GEMMs). The Scientist will play a central role in developing and managing faithful disease models in vivo (e.g., GEMMs, surgically induced murine models) to support immuno-oncology research and translational efforts. This position offers the opportunity to engage in high-impact research with translational potential, contributing directly to developing novel cancer immunotherapies. Maintaining an up-to-date knowledge of, and having a high level of enthusiasm for, new and emerging technologies in preclinical murine modelling for immuno-oncology and their potential applications will be important. This includes beta-testing new tools, customizing technologies to fit CEPIO's research needs, and developing in-house protocols for complex experiments. The ideal candidate will work with collaborators across CEPIO with the goals of establishing faithful models to enable and support immuno-oncology research and translational efforts. Responsibilities Coordinate multiple aspects of research projects and execute laboratory experiments utilizing appropriate laboratory techniques, tools, and methods. Provide inputs regarding research protocols and experiments, set up protocols, and assist in developing new laboratory techniques as required. Identify, process, organize, summarize, review, and report relevant experimental data. Draft sections of research manuscripts as directed. Support monitoring and stocking of supplies, and calibration, maintenance, troubleshooting, and purchase of equipment within area. Instruct other staff in basic laboratory techniques and procedures. Design, troubleshoot, and refine experimental approaches to answer critical research questions. Process, organize, and analyze complex datasets, providing detailed reports on findings. Provide technical support for ongoing projects, including maintaining datasets, lab documentation, and compliance with safety regulations. Engage in collaborative research projects with internal and external teams to advance research and translation in immuno-oncology. Maintain regular and predictable attendance, contributing to a positive and productive lab environment. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Prior experience in lab techniques is preferred. Experience in lab and scientific project coordination, maintenance, and other research support activities preferred. Prior experience with the generation of GEMMs in immunology and/or cancer biology is highly preferred. Professional Growth Opportunities CEPIO provides a vibrant research environment with access to advanced tools and resources, including state-of-the-art imaging platforms and cutting-edge molecular biology techniques. CEPIO fosters a culture of collaboration, offering opportunities for professional development and advancement. We invite motivated scientists passionate about preclinical murine models and immuno-oncology to apply and join us in pushing the boundaries of immuno-oncology and immunotherapy in the fight against pediatric cancers. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Preclinical Modeling Scientist - Center of Excellence for Pediatric Immuno-Oncology. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The Scientist or Associate Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results. We are seeking a motivated Scientist or Associate Scientist with a background in neural circuits to join the lab of Dr. Bikoff in the Department of Developmental Neurobiology at St. Jude Children's Research Hospital in Memphis, TN. The goal of our research is to understand how neural circuits control movement. We approach this from multiple perspectives, using diverse technologies to analyze the molecular heterogeneity and connectivity of spinal neurons, explore how descending systems in the brain convey information to the spinal motor system, and define the functional roles of spinal interneurons in generating behavior. This position broadly focuses on understanding the synaptic and circuit organization of neurons in the spinal cord that enable us to move. Specifically, the successful candidate will investigate the connectivity of genetically defined populations of spinal interneurons using a diverse set of approaches, including expansion microscopy, tissue clearing and light-sheet imaging, as well as viral tracing and transcriptomic methodologies. We welcome applicants from diverse backgrounds who would thrive in a highly collaborative, fun, and supportive environment that also provides the freedom to independently develop a research project. The Ideal Candidate will have: A PhD in neuroscience or related discipline Prior experience in studying neural circuits Familiarity with programming languages (e.g. R, Python) and an ability to work with large datasets Strong record of peer-reviewed publications Ability to independently design and execute experiments and interpret data Ability to work in a multidisciplinary, highly collaborative environment Excellent oral and written communication skills The Bikoff lab is strongly committed to providing individual mentoring and training, as well as ongoing support at all stages of career development. At St. Jude, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted by a lack of resources. Minimum Education and/or Training: Bachelor's degree in a relevant scientific area is required Scientist Minimum Experience: Eight (8) years of relevant work experience is required Six (6) years of relevant work experience is required with a Master's degree Three (3) years of relevant work experience is required with a PhD Salary range: $86,320.00/yr.-$154,960.00/yr. Associate Scientist Minimum Experience: 7 + years of research experience is required 5 + years of research experience is required with a Master's degree 2 + years of research experience is required with a PHD Experience leading and supporting research experiments preferred Salary range: $65,520.00/yr. - $114,400/yr. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist or Associate Scientist in Neural Circuits and Movement (Jay Bikoff Lab). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Performs a variety of laboratory techniques independently and presents results. A Scientist or Associate Scientist position is available for a highly motivated data scientist with a background in Computational Neuroscience to analyze complex time-series data from ongoing 2-photon microscopy experiments and animal behavior studies. This position is well-suited for an individual interested in transitioning from a postdoctoral position to a more stable, long-term position. The successful candidate will lead an independent research project dedicated to identifying abnormal neuronal activities in circuits of murine models of 22q11.2 and 3q29 deletion syndromes, two rare conditions that confer the highest genetic risks of schizophrenia. Key Responsibilities: Develop and implement advanced algorithms for analyzing calcium or voltage imaging and behavior data Create robust analysis pipelines to process large-scale time-series datasets Test and develop new methodologies to extract meaningful patterns from complex neural data Collaborate with interdisciplinary researchers to translate findings into biological insights Contribute to publications and presentations of research findings Performs other related duties as assigned in order to meet the goals of the department and institution. Maintains regular and predictable attendance Qualifications: PhD in computational neuroscience, physics, mathematics, computer science, or related fields. Demonstrated hands-on experience with machine learning techniques. Strong programming skills (Python preferred). Experience analyzing time-series data, preferably from neuroimaging or behavioral studies. Knowledge of signal processing and statistical analysis. Excellent communication skills and ability to work in a collaborative environment. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required Scientist Minimum Experience: Ten (10) years relevant work experience is required Eight (8) years of relevant work experience is required with a Master's degree Five (5) years of relevant work experience is required with a PhD Minimum Experience: 7 + years of research experience is required 5 + years of research experience is required with a Master's degree 2 + years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel preferred Proven performance in earlier role/comparable role Preference will be given to applicants who have a strong background in leveraging cutting-edge AI and machine-learning techniques to solve complex problems in Neuroscience. The candidate also will benefit from an outstanding, highly collaborative work environment in which a diverse team of researchers is focusing efforts toward understanding the mechanisms of schizophrenia and other psychiatric disease behaviors at the levels of neural circuits and individual neurons, synapses, and molecules. The Zakharenko laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for in vivo and ex vivo neuroimaging, behavioral phenotyping, computational neuroscience, genetic engineering, and single-cell genomics. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies. St. Jude Children's Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should send their CVs and the names and addresses of 3 references to: Stanislav Zakharenko, M.D., Ph.D. Department of Developmental Neurobiology, MS 322 St. Jude Children's Research Hospital 262 Danny Thomas Place Memphis, TN 38105 ******************************* Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist or Associate Scientist - Computational Neuroscience. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

St. Jude is seeking a Senior Bioinformatics Research Scientist for data science projects within the Center for Pharmacogenomics in the Department of Pharmacy and Pharmaceutical Sciences. In particular, this individual will focus on electronic health record (EHR)-driven phenotyping to support pharmacogenomics discovery research. The successful candidate will be responsible for developing and implementing new informatics tools and resources to enhance phenotyping performance or enable deep phenotyping through terminology/ontology, natural language processing, and machine learning. The role involves working with large external biobank datasets such as All of US, eMERGE, TopMed, UK BioBank, as well internal EHR data. This Bioinformatics Research Scientist will collaborate extensively with disease and/or drug experts (clinicians, clinician scientists, data scientists, and laboratory investigators) to co-develop phenotyping algorithms but is expected to serve as the domain expert in high-throughput phenotyping. Demonstrated expertise in EHR-based phenotype extraction and curation are strongly preferred. Responsibilities o Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data. o Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion. o Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions. o Assist in the evaluation and testing of new methods and technologies. o Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so. o Participate in the department's developmental projects and interdepartmental team projects. Qualifications o Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work experience in relevant area (e.g., bioinformatics, cheminformatics, statistics/computer science with a background in biological sciences or chemistry) (OR) Master's degree with 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience. o Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred. As one of the premier pediatric research institutions in the world, St. Jude Children's Research Hospital provides exceptional resources and a supportive environment for career development. In this position, the candidate will interact with leaders in pharmacogenomics and data science in general within and outside the institution and at national/international meetings. Innovation and independence are encouraged with the goal of providing flexibility and freedom in exploring new directions. Job Responsibilities: Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data. Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion. Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions. Assist in the evaluation and testing of new methods and technologies. Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so. Participate in the department's developmental projects and interdepartmental team projects. Perform other duties as assigned to meet the goals and objectives of the department and institution. Maintains regular and predictable attendance. Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data. Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion. Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions. Assist in the evaluation and testing of new methods and technologies. Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so. Participate in the department's developmental projects and interdepartmental team projects. Minimum Education and/or Training: Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master's degree or PhD preferred. Minimum Experience: Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.