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  • Senior Scientist LCMS

    Resolian

    Senior scientist job in Malvern, PA

    Responsibilities · Prepare reagents, standards, and control samples · Analyze samples using various techniques specific to department · Independently design and develop methods · Perform method validation or qualification · Operate analytical equipment · Technical resource for troubleshooting activities; assays and equipment · Maintain analytical equipment · Review, evaluate, and interpret data results · Draft and present posters/presentations · Train and mentor lower level Scientists · Collaborate with clients and vendors · Ensure lab area is clean and inspection ready at all times · Remove lab waste · Collaborate across teams, departments, and sites · Evaluate and establish processes to improve quality and efficiency · Record tasks in accordance with Good Documentation Practices (GDP) · Knowledge of regulatory requirements; GLP, GCP, 21CFR Part 11 · Follow applicable SOPs and procedural documents · Other tasks as assigned Education, Experience & Skills Required · BA/BS or higher with 11-12 years lab experience; all experiences will be evaluated · PhD in relevant field with 3-5 years lab experience · Knowledge and understanding of regulatory requirements; GLP, GCP, 21CFR Part 11, GDP, GMP · Able to independently develop and perform complex lab work · Able to work in a regulated environment · Able to work effectively and contribute within a team · Able to work with computer systems · Able to document clearly · Able to communicate clearly Physical Demands · Must be able to sit at a desk for up to 6 hours per day · Walking and/or standing as required for the rest of the working day · Must be able to occasionally lift 15 lbs.; this includes lifting boxes, equipment, etc. · Bending or standing as necessary · The length of time of these tasks may vary from day to day and task to task
    $78k-111k yearly est. 4d ago
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  • Scientist/Sr. Scientist - Repository

    Coriell Institute for Medical Research 3.5company rating

    Senior scientist job in Camden, NJ

    Coriell Institute for Medical Research is currently seeking an experienced Scientist (Senior Scientist depending on experience) to join the biobanking team. The ideal candidate for this role is a PhD in genetics, cellular or molecular biology, biochemistry, or related field with postdoctoral experience and 2+ years of experience in project and resource management. We are interested in meeting candidates with proven ability to effectively collaborate with scientists and other department leads to oversee biobanking operations and biospecimen and associated data management pipelines. S/he will work to cultivate long-term relationships with project managers, internal and external stakeholders, and ensure effective and regular communications. This role also offers opportunities to publish and present to the wider scientific community. Potential candidates must be team players with excellent organizational, written and verbal communications skills. Reporting to the Chief Biobanking Officer, the incumbent for this role will ensure that Coriell meets or surpasses biobanking standards for quality service and deliverables. Biobanking operational efforts include overseeing the growth of the biobanking collections via recruitment, submitter and biospecimen submission management; overseeing biospecimen processing, quality control and storage; overseeing biospecimen distribution; all under Coriell's quality management framework. Day to day responsibilities include but are not limited to: Supporting delivering grant and contract requirements Supporting internal and external reporting requirements Supporting efficient, productive daily biobanking operations Managing relationships with internal and external stakeholders Supporting the Project Management team in ensuring deliverables are met in a timely manner Serving as a technical expert providing scientific advice and leadership as needed Developing and maintaining outreach efforts to submitters and end users of the biobank Overseeing the submission of specimens to the biobank in accordance with the OHRP regulations, following guidelines established by Program Directors and Scientific Advisory Committees Reviewing data (demographic, clinical, genomic) at the time of sample submissions to determine appropriateness and completeness Contributing compelling, innovative ideas for continued strategic growth for the biobank Representing and promoting Coriell and the biobanking collections at scientific meetings Participating in Coriell strategic initiatives and task forces Contributing to external funding opportunity applications Adhering to internal standards, policies and procedures Performing other duties as assigned. Strong management skills, excellent communication, and the ability to work alongside senior management and contribute to the growth of the institution are vital for this role. If you are interested in applying for this opportunity, please email a cover letter and resume to *******************. Please include a detailed description of your relevant experience in your cover letter. Applicants are encouraged to highlight their background with non-profit, medical, healthcare, academic, and/or scientific research organization(s). This role starts at $85,000/Year, but will be commensurate with relevant experience. Coriell & Recruitment Now in its 73rd year, Coriell Institute for Medical Research is an independent non-profit research center dedicated to the study of the human genome. Expert staff and pioneering programs in the fields of molecular and cellular biology, genetics, genomics and epigenomics, and biobanking drive our mission. To learn more, visit **************** Any offer of employment extended by Coriell is contingent on an applicant's ability to be Authorized to Work in the United States of America. Upon date of hire, all employees are required to provide whichever valid Employment Authorization Documents they wish, as long as it is in compliance with Federal Regulations. This /posting is to provide general guidance on the nature of work that will be performed in this position. It is not represented to be a full or exhaustive list of the duties, responsibilities, or qualifications needed for this role. Due to the nature of our work, the duties, responsibilities, and qualifications listed on this job description/posting are subject to change.
    $85k yearly 14h ago
  • Senior Scientist, Analytical Research & Development

    Veranova

    Senior scientist job in West Deptford, NJ

    Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Sr. Scientist is responsible for the implementation, development, and validation of analytical test methods in support of process research, and cGMP production with emphasis on development of LC, GC, GC-MS and LC/MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc) methods for small molecules, ADCs, Oligonucleotides and Peptides Major support functions include sample analysis by various analytical techniques including HPLC, GC, LC-MS/MS, GC-MS, ICP-MS, CE, SEC-MALS, CE-SDS, cIEF, NMR, KF, titrations, and instrumental and wet chemical techniques. Other duties may involve analytical method modification, development, and validation. The incumbent may function as the primary contact on one or more development projects. In- depth involvement with the project team concerning the chemistry of the project and analytical chemistry needs is expected Core Responsibilities: Develop and validate new analytical procedures. Independently, detects and solves complex problems of high technical difficulty. Perform sample analysis using various analytical techniques (e.g., LC, GC, LC-MS, GC-MS, ICP-MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc.), interpret results, and prepare high-quality documentation such as protocols, analytical reports, and summary reports. Document all analyses per SOPs. Prepare SOPs, test methods, and other GMP documentation. Independently, detect and solve complex problems of high technical difficulty. Apply knowledge and expertise from multiple disciplines (including QA, QC, Analytical and production) to achieve project goals. Conduct investigations independently. Troubleshoot analyses and instruments. Support qualification of reference materials. Develop new analytical procedures. Validate analytical methods. Prepare and review scientific reports. Interface with internal and external clients. Qualifications: PhD in Analytical Chemistry or equivalent Minimum of 8 years' experience in a GMP environment. Minimum of 5 years' experience in method development and validation for small molecules Active Pharmaceutical Ingredients (APIs). Experience with Process Development of APIs. Experience with LC, GC, GC-MS, LC-MS, IC, spectroscopy, and wet chemistry. Experience mentoring staff members in an analytical department. Formal project management training. Experience with writing method validation protocols and reports desirable. Experience with Microsoft Office and other complex computer software (UPLC, Empower 3) desirable. Salary Range : $115,000 - $125,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
    $115k-125k yearly 2d ago
  • Forensic R&D Technical Scientist

    UCT Inc.

    Senior scientist job in Bristol, PA

    United Chemical Technology (UCT) was founded in 1986 by one of the pioneers of Solid Phase Extraction (SPE), Michael Telepchak, who is still active in the Company and continues to works with our team of talented chemist in our research and development department. UCT is a major competitor in the field of silica based phase extraction technology and silane manufacturing. UCT's mission is to establish and maintain a leadership position in the specialty chemical market for organosilicon products. Our products serve the environmental, forensics, food and beverage, clinical, pharma and cannabis industries. As a company, we consistently strive to distinguish ourselves from competitors in terms of service, pricing and quality. To accomplish this goal, we continue to invest in the best people, providing them with the finest tools available. Through excellence, UCT is committed to meeting not only the customer's needs of today but also those of tomorrow. This role involves developing applications and opportunities in our sample preparation product lines through authoring articles, white papers, posters, and technical presentations. The candidate will be a valued core member of the UCT R&D team, assisting with customer technical support, providing on-site support when required, and traveling with the sales team as needed. Key duties and responsibilities include: Drive R&D initiatives by executing laboratory project goals under the guidance of the R&D Team Manager, contributing to new product development, experimental evaluations, and preparation of application notes. Independently initiate and develop SPE applications by exploring innovative uses for existing products to expand their applicability in forensic and toxicological workflows. Staying current with emerging trends and techniques and applying UCT products to new applications for evaluation and comparison. Collaborate with Quality Control as needed to design evaluations and experiments that enhance product testing and performance. Publish at least two scientific papers or posters annually on newly developed applications of UCT products. Actively participate in professional organizations (e.g., AAFS, SOFT) to expand knowledge of SPE applications in forensic and toxicological fields. Provide timely and accurate technical support for customer inquiries and sales requests, addressing their needs effectively. Support our technical continuing education program by developing and maintaining training and workshops for the Sales Team, distributors, and customers, educating them on the effective use of UCT products and relevant forensic toxicology knowledge to enable productive sales interactions and technical discussions. Must be available to travel up to 30% of time to include applicable conferences and tradeshows, domestic/international customer visits, and distributor training. Promote a culture of safety, collaboration, and effective teamwork across the group and other company departments. Other duties as assigned. Skills & Abilities: Strong experience in sample preparation method development in an R&D environment, particularly with SPE and QuEChERs products (preferred) Proven ability to work independently in the laboratory, utilizing LC-MS/MS and GC-MS instrumentation, while applying analytical problem-solving skills. Ability to evaluate current products and recommend improvements for UCT's products and their applications. Highly adaptable and organized, capable of managing multiple projects simultaneously and delivering results on schedule. Effective collaborator and team leader, with strong communication skills to convey complex technical information and support cross-functional decision-making. Education & Experience: Bachelor's degree in Forensic Toxicology, Chemistry, or a related field, with an emphasis on chemical analysis; Master's degree preferred. Minimum of 3 years' experience in a forensic laboratory performing drug analysis and method development. Hands-on experience using sample preparation products (SPE, QuEChERS) in conjunction with GC, LC, GC-MS/MS and LC-MS/MS. Demonstrated ability to develop new methods, establish validation criteria, and define specifications. Familiarity with competitors' products and a strong interest in toxicological analysis. Awareness of current industry trends and emerging approaches in analytical method development. UCT is committed to the principles of equality in employment. It is contrary to our policy to discriminate against individuals because of race, color, creed, ethnicity, religion, ancestry, age, national origin, sex (including childbirth, or related medical conditions), sexual orientation, gender identity or expression, genetic information, physical or mental disability, union affiliation, citizenship status, marital status, pregnancy, military or veteran status or any other status prohibited by applicable federal, state or local law (“protected category”). Equal employment opportunity applies to all terms and conditions of employment, including hiring, placement, promotion, termination, layoff, recall, transfer, leave of absence, compensation, and training. UCT explicitly prohibits any form of unlawful employee harassment or discrimination based on any of the characteristics mentioned above. Improper interference with the ability of other employees to perform their expected job duties will not be tolerated.
    $67k-95k yearly est. 2d ago
  • Scientist - Cellular Immunogenicity

    Insight Global

    Senior scientist job in Spring House, PA

    Our large pharmaceutical company is seeking a Scientist to join their growing Bioanalytical Discovery and Development Sciences group in Spring House, Pa. The Bioanalytical Discovery and Development Sciences (BDDS) organization develops, validates, and conducts bioanalytical sample analysis across R&D portfolios from discovery through development. We are looking for a dedicated scientist to design and perform cellular immunogenicity assays within BDDS for projects spanning all modalities and therapeutic areas from nonclinical studies to post-market clinical development. Other responsibilities include: Performs method development, validation, GLP/GCLP bioanalysis and reporting for various cellular immunogenicity assays including ELISpot, multiplex FluoroSpot, multi-parametric flow cytometry to assess preclinical and clinical safety and efficacy of various modalities and programs including ADCs, gene therapy, cell therapy, therapeutic vaccines, si RNA, therapeutic antibodies, etc. Promotes assigned project activities through hands-on data generation, QC and data analysis. Utilizes advanced computer software packages to collect, analyze, and interpret cellular immunogenicity data. Sets priorities for experimental work to ensure adequate progress of team projects and objectives. Ensures laboratory productivity as well as compliance with good laboratory practices and other regulatory guidelines. Qualifications MS or Ph.D. degree in Life Sciences, Biology, Immunology or related fields. 2 years of mammalian cell culture experience Experience with processing human and/or animal tissues Aseptic techniques and familiarity with BSL2 safety practices Salary: $85,000-$100,000 (flexible based on experience) Hours: Monday-Friday, 8:00am-5:00pm Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year PTO: 10 PTO days, 6 paid sick days annually & paid Holidays Benefits: Medical, Dental, Vision and 401K plans available Exact compensation may vary based on several factors, including skills, experience, and education. Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.
    $85k-100k yearly 4d ago
  • Research/Sr. Research Investigator, High-Throughput Experimentation (HTE)Process Chemist

    Incyte Corporation 4.8company rating

    Senior scientist job in Wilmington, DE

    Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. Job Summary (Primary function) This role will leverage high-throughput experimentation to drive process optimization, support automated impurity synthesis in process and library synthesis in collaboration with discovery, scale-up manufacturing and generate structured datasets to train AI models for predicting yield, selectivity etc. in process development. Essential Functions of the Job (Key responsibilities) * Execute high-throughput experimentation (HTE) to identify optimal reaction conditions for process development, enabling efficient, scalable, and robust chemical processes. * Operate and maintain HTE and automation equipment, ensuring daily functionality, troubleshooting issues, and coordinating timely repairs with vendors and service providers. * Participate in data integration out of HTE experiments into AI-driven modeling pipelines, continuously refining predictive models for reaction yield, selectivity virtual screening. * Participate in cross-functional collaboration with Process Chemistry, Discovery, QC, QA, and external partners. * Provide scale-up support for drug candidates in both non-GMP early development and cGMP clinical production, including route design, reaction optimization, and cost-effective manufacturing strategies. * Support technology transfer to Contract Research Organizations (CROs) and Contract Manufacturing Organizations (CMOs) and review cGMP manufacturing documentation. Qualifications (Minimal acceptable level of education, work experience, and competency) * PhD in organic chemistry, or equivalent relevant industry experience. * Expertise in high-throughput experimentation (HTE), automation and workflows to support AI-driven modeling and decision-making. * Strong proficiency in synthetic organic chemistry, with deep understanding of reaction mechanisms and synthetic methodologies and a proven publication record. * Demonstrated excellence in problem-solving skills, with sound, technically driven decision-making ability. * Outstanding written and verbal communication skills and interpersonal skills. * An innovative team player with high energy for dynamic company environment. * On-site presence required. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. We Respect Your Privacy Learn more at: privacy-policy The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate. During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here. You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable). Please contact if you have any questions or concerns or would like to exercise your rights.
    $136k-169k yearly est. 4d ago
  • Imaging Research and Development Scientist

    Eli Lilly and Company 4.6company rating

    Senior scientist job in Philadelphia, PA

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Organization Overview: At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Responsibilities: Lilly Imaging/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The scientist will provide expertise for biological assay development for the discovery and characterization of novel PET imaging agents, with a focus on neuroscience or oncology imaging and other therapeutic areas. This scientist will work independently, coordinating experimental details of internal and external partnered projects, conducting experiments him/herself, performing data analysis, and presenting data to internal teams and the international scientific community. Establish and execute imaging research projects supporting oncology, neuroscience or other drug discovery and biomarker projects Design and conduct novel binding assays, including radioligand binding assays Characterize and purify biological targets Collaborate with internal project teams, implement translatable imaging biomarker assays and ensure seamless translation of projects Publish results of research projects as appropriate Participate in extramural scientific organizations and attend scientific symposia as well as workshops in order to continue educational/professional development Other duties as assigned Basic Requirements: Degree in physical or biological sciences or imaging-related field Bachelor's degree with min of 15 years' experience, master's with a min of 12 years' experience, or PhD in scientific field. Experience with in vitro assay development Peer-reviewed publications Additional Skills/Preferences: PhD degree preferred Experience in Oncology or Neuroscience, preferably in molecular imaging Experience designing and executing novel biochemical, cellular and tissue assays, including radioligand binding assays (e.g. filtration binding, ELISA/AlphaLISA, SPR and LC/MS) Experience working with amyloidogenic proteins Demonstrated ability to independently conceive, design and execute the characterization and purification of biological targets Experience in drug discovery of PET molecular imaging agents Peer reviewed publications Willingness/desire to learn and incorporate additional technologies or therapeutic area biology to address imaging needs Excellent communication skills (both written and verbal) Excellent presentation skills Strong organizational skills and ability to effectively manage multiple priorities Creativity and critical thinking skills Team Player Additional Information: Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $121,500 - $198,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly
    $121.5k-198k yearly Auto-Apply 60d+ ago
  • Scientist II

    Legend Biotech Us 4.1company rating

    Senior scientist job in Philadelphia, PA

    Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Scientist II as part of the R&D Novel Car Design team based in Philadelphia, PA. Role Overview We are seeking a highly motivated and creative scientist to grow our pipeline efforts. The successful candidate will be part of Legend Biotech, a leading cell therapy company with commercial CAR drug product CARVYKTI and an attractive pipeline portfolio. The candidate will be an integral part of our R&D team, whose aim is to research, develop and advance the next generation of cell therapies using cutting edge in vivo gene delivery technologies and create innovative novel CAR designs for a wide range of human indications. This position will focus on in-vivo CAR. The position requires enthusiasm, passion, outstanding skills in the art, attention to detail, and a desire to create new medicines for patients. Key Responsibilities Be able to work independently under minimal supervision. Lead, design and optimize research with aims of exploring next generation cell therapies using in-vivo CAR virus Perform functional characterization of T cells transduced with in-vivo CAR virus using multiple functional assays but not limited to cytotoxicity assay, serial cytotoxicity assay, and cytokine release assay etc. Help execute the evaluation of in-vivo CAR virus using in-vitro assays and in-vivo mice models. Design, execute and interpret research requiring molecular biology techniques including PCR/DDPCR/ qPCR, NGS, RNA and DNA analysis. Perform research requiring cell biology techniques including cell culture, transfection, FACS, and cellbased assays. Analyze and present data to a wide range of audiences of internal group meetings and other forums. Dissect published literature to find novel solutions to in-vivo cell therapy problems. Generate, manage, evaluate, and maintain critical data in a highly organized manner. Requirements PhD in Biology or related discipline 3 years of experience in the field of cell therapy with cell culture methods (T cells, CAR-T or TCR-T preferred), quantitative PCR and functional characterization of T cells (Cytotoxicity assay using Incucyte or xCelligence, and MLR assay). Prior experience with in-vivo CAR virus evaluation will be preferred. Proficient in cell-based assays with various read out technologies such as flowcytometer, Incucyte, Xcelligence. Experience with transfection and lentivirus or retrovirus transduction. Experience/ working knowledge (molecular biology and cellular biology) in design and evaluation of modified viruses. Individual should be go-getter and be able to work independently. Excellent written and oral communication skills. #Li-JR1 #Li-Hybrid The anticipated base pay range is $107,482 - $141,070 USD Benefits We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles. We offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Please note: These benefits are offered exclusively to permanent employees. Contract employees are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions. Legend Biotech maintains a drug-free workplace.
    $107.5k-141.1k yearly Auto-Apply 60d+ ago
  • Scientist II

    Artech Information System 4.8company rating

    Senior scientist job in Fort Washington, PA

    LanceSoft is a nationally certified Minority Business Enterprise (MBE) that has established itself as a pioneer in providing highly scalable, cost-effective workforce solutions to a diverse set of customers across various industries in the United States. Headquartered in Virginia, LanceSoft currently operates out of several locations in the US and Canada. Title: Scientist II Location: Fort Washington, PA Duration: 12 Months Job Description: II. Position Summary: Provides testing, technical and troubleshooting support in the QC laboratories. These functions include: Collection, processing, method development and testing of chemical components, bulk products, raw materials, packaging components, finished products, marketed product stability, in-process materials, scale up, validation and cleaning validations to conform with specifications and standard operating procedures (SOPs). Thorough knowledge of SOPs, USP and other applicable pharmacopeia. Possess foresight to recognize task needs and performs the trained task without the request of management. Reviews and/or writes the following documents: APR, SOPs, QSRs, Instrument qualification, protocol/report writing, trending and review/analysis of data. Performs statistical analysis in support of APRs, Stability, and Product Release. Complies with cGMPs, safety training and regulations. Performs more advance technical projects under the supervision of management. Maintains an environment of respect and teamwork with all coworkers. The Company's management reserves the right to add, delete or otherwise alter assigned duties at any time. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. III. Responsibilities: (Define key accountabilities and/or activities.) Under limited supervision and in accordance with all applicable federal, state and local laws/regulations, the Companies' policies, procedures and guidelines, this position: Ensure quality and compliance in all my actions by: o Attend GMP training on the schedule designated for my role and as appropriate for my role o Adhere to strict compliance with procedures applicable to my role. o Exercise the highest level of integrity in the tasks that I perform o In a timely and prompt manner, identify report and seek correction for deviations noted in my workplace. o Embrace a behavior of employee involvement and commitment to doing the job right the first time Systems Knowledge • Be a Power User in the applicable systems and roles assigned. • Trained to the role in which you are assigned as required for your job function in the applicable systems • Utilize tools within MS office and other systems to improve business effectiveness • Exposure to & working knowledge of electronic batch records and/or other automated processes/systems (labs) • Working knowledge of SAP or ERP system; including other relevant systems per role • Working knowledge of an automated system. Product Knowledge • Understanding of product family, product size and put-up, and product characteristics (color, viscosity) associated active and excipient. Critical parameter associated with all processing steps. Training • Can act as SME and be a curriculum owner. • Partner with training department to create training materials including curricula. • Can act as qualified trainer in specific areas. • Participate in all trainings. • Ensure all trainings are completed on-time. Investigations • Assists in gathering information and documentation as required. • Participates in investigations as required. Compliance - Safety, GMP, Facilities • Provide support during regulatory inspections /audits as directed. Support may be in the form of scribes, runner, and document gathering. • Attend GMP training on the schedule designated for the role and as appropriate for the role. • May provide statistical analysis in support of the APR and Stability processes. • Adhering to strict compliance with procedures according to the roles and responsibilities. • Exercises the highest level of integrity in the tasks performed • In a timely and prompt manner, identify report and seek correction for deviations noted in the workplace. • Embrace a behavior of employee involvement and commitment to doing the job right the first time. • Strong working GMP knowledge. Communicates and identifies GMP gaps. • Can participate in all types of audits & Inspections. • Leads areas in ensuring all operations (processes) are completed in a compliant and safe manner. • Assists in coordination efforts in case of emergency- spill, fire etc. • Takes necessary action to eliminate and immediately address safety hazards. Communicate any observed unsafe behaviors immediately. • Understands the safety concerns and promotes a safety conscience culture for their job function. • Wears the appropriate PPE when working in manufacturing and other hazardous working environments and advocates standards of safety. • Contributes and attends all EHS programs as assigned. • Promptly communicates deficiencies to management. • Maintains facility and work area in good working condition. • Works with team to ensure all aspects of business remain compliant. Documentation Management • Edits documentation (i.e. Standard Operating Procedures, work instructions) as necessary. • Perform/assist in the completion and documentation of the process steps as per the documentation directives. • Complete visual verification of the process and document these steps in the appropriate system. • Document all activities per the GMP requirements. Process Excellence, Lean, Continuous Improvement, ME2 • Completes PE/ Lean awareness training. • Proactively identifies opportunities for continuous improvement and proposes actions to address these opportunities. • Participates and leads continuous improvement implementations and kaizen events. Understands and applies PE tools in daily work activities. Leadership • Job expert that less experienced personnel can go to for assistance. • Provides leadership in absence of supervisors (for short periods). • Assist management through change and transformation activities. • Facilitates departmental meetings and may assist in the coordination of other scheduled meetings. In absence of management, attends meetings on his/her behalf. • Continuously demonstrates all GLP values; specifically: integrity and credo based actions, self awareness and adaptability, results and performance driven, organization and talent development, and collaboration and teaming. Demonstrated behaviors include: fairness, honesty, consistent and ethical behaviors, empathy and collaboration. • Contributes and supports an environment that fosters diversity and inclusion. • Exhibits and lives core values and behaviors. • Contributes to a climate of open communication, engagement and ownership within team. • Builds working relationships • Provides feedback to site management • Supports strategic and tactical plans in alignment with site's mission and plans. IV. Requirements: Education: Bachelor's Degree in Microbiology, Chemistry, Biology, Natural Science, Medical Technology, or related science is required Experience: Minimum 2 years of GMP/GLP quality control lab experience in a pharmaceutical and/or OTC and/or regulated environment is required. Physical Demands: Capable of performing routine laboratory activities. Light to moderate lifting Knowledge, Skills and Abilities: Basic knowledge/exposure of a LIMS system is preferred Additional Information Regards, Anuj Mehta ************
    $70k-102k yearly est. 60d+ ago
  • Senior Scientist - Ink Formulation

    Penn Color 4.5company rating

    Senior scientist job in Hatfield, PA

    Who We Need We are seeking a Senior Scientist to join our R&D Inks & Coatings group. You will work alongside an outstanding team in designing and formulating both water and solvent based inks ad coatings for printing applications (primarily for rotogravure and flexography). Responsibilities: Design and formulate water & solvent based inks and coatings. Modify existing inks and coatings to meet customer requirements. Lead and support projects from lab formulation to commercialization. Work closely with raw material suppliers and internal procurement department for bringing alternate raw materials or for qualifying new raw materials. Generate and analyze data after conducting standard tests on inks and coatings. Occasional domestic travel to customers for attending technical meetings or print trials. Interact with customers to understand and define the scope of project. Regularly interact with sales, procurement and production during various stages of new product development. Other duties as assigned. Knowledge/Skills/Experience: 5-8 years minimum experience in formulating inks for printing applications. Prefer experience in ink formulation for rotogravure printing process. Experience or familiarity with printing processes such as rotogravure, flexography, screen printing and industrial digital printing. Knowledge on working with film/substrates like PVC, BOPP or PET. Able to work in highly customer focused laboratory settings. Proficient in DOE and able to work with R&D management workflow software. Ability to work in 5S and safe environment. Displays good verbal and written skills. What WE Can Do For You Penn Color offers many tangible and intangible benefits to our full time employees: Tangible benefits include: Highly competitive compensation A choice between 3 outstanding medical plans 401K with a strong company match PTO to balance your life Additional company perks And More! Our intangible benefits really set us apart: Unmatched company stability Long-term career opportunity True open door, friendly environment Ability to "own" your role Company events that bring us all together If you desire a long-term career, want to work alongside an exceptional group of people, and wish to use your talents to shape a world-class company, then we are your employer of choice! Together, we will illuminate the world! Penn Color, Inc. is an Equal Employment Opportunity employer. We adhere to a policy of making employment decisions without regards to race, color, religion, sex, age, disability or any other protected categories. It is our intention that all qualified applicants be given an equal opportunity and that selection decisions be based on job-related factors.
    $82k-111k yearly est. Auto-Apply 60d+ ago
  • Cell Culture Scientist

    Invitrogen Holdings

    Senior scientist job in King of Prussia, PA

    Join us as a Scientist! At Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future. Our PPD Laboratory Services team has a direct impact on improving patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. As the world leader in serving science, our laboratory professionals bring their commitment to accuracy and quality to deliver groundbreaking innovations. As a Scientist, your role will be to perform advanced diagnostic testing and analysis, ensure the accuracy and reliability of laboratory results, troubleshoot complex technical issues, and contribute to the continuous improvement of lab procedures and quality standards. What You'll Do:Position will provide support for upstream bioreactor operation and maintenance. This list is not all-inclusive list, but person will be responsible for ordering of raw materials and lab supplies, coordinating receipt of frozen cell bank vials, cell banking, media preparation, reactor preparation, vial thaw, shake flask culturing, inoculation of bioreactors, sampling, harvest, cleaning.Key Responsibilities: Single point of accountability support of the upstream E.coli microbial fermentation suite. Documentation of raw materials and experimental data in compliance with SOP and data integrity requirement; supporting preparation of technical documentation/report for internal communication with project team and management Completing inventory management (Cell culture medium preparation, Reagent and consumable procurement/organization/tracking) and lab housekeeping related with cell line maintenance. Working with banked cells and growing them from shake flask to full bioreactor status all while sampling and maintaining cell line. Maintain training records and familiarity with current SOPs and controlled documents Work to Lab standards as appropriate Follow safe Laboratory Practices, regular safety training, and maintain accurate and complete safety records consistent with company policy and legal requirements Knowledge, Skills and Abilities: Knowledge of biological and pharmaceutical product manufacturing and microbial control Clean in Place (CIP) and Sterilize in Place (SIP) practices for Stainless Steel reactors Strong team working skills, able to effectively work across interdisciplinary groups Capacity to think innovatively and flexibly, comfortable with complexity. Education and Experience: • Bachelor's degree or equivalent and relevant formal academic / vocational qualification • Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years). Why Join Us? When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You'll work in an environment where collaboration and development are part of the everyday experience - and where your contributions truly make a difference. Apply today to help us deliver tomorrow's breakthrough.
    $63k-92k yearly est. Auto-Apply 5d ago
  • Pharmacovigilance Scientist

    Pioneer Data

    Senior scientist job in Horsham, PA

    The Scientist role is primarily responsible for aggregate safety analyses and aggregate report writing. He/she will contribute or will be responsible for report writing and/or report ownership related to core safety deliverables including scheduled and ad hoc post-marketing aggregate reports. Daily activities involve database searching, aggregate safety analysis and case level review, writing, planning, conducting meetings, and project management/coordination of strategic safety documents. The Scientist will partner with team members, stakeholders such as safety physicians, and a vendor. The Scientist must be able to work on multiple projects simultaneously and prioritize tasks. Responsibilities: Scientist would be responsible to contribute to or serve as report owner for scheduled and non-scheduled post-marketing safety reports and other deliverables as applicable. Scheduled reports include PBRERs/PSURs, PADERs, Addendums to Clinical Overview, and PBRER/PSUR Addendum Reports. Non-scheduled reports include Ad hoc reports in response to health authority queries or internal requests, health hazard evaluations, and labeling support documents. Ensure timely, quality deliverables for assigned tasks related to core deliverables with oversight as appropriate Initiate/conduct searches of internal and external databases Perform aggregate safety analysis and case level review Present results at Safety Management Team meetings as needed Author/contribute to the preparation of core safety deliverables Partner with vendor to develop reports/deliverables Comply with processes and ensure appropriate documentation Utilize technical skills and programs to analyze and organize data (e.g., Excel pivot tables, SAS JMP) Adhere to report timelines and escalate issues to management as appropriate Qualifications/Experience Required Bachelor s degree in health or biomedical science (3+ years industry experience or equivalent) or Advanced degree preferred in health or biomedical science (2+ years industry experience or equivalent) Clinical/medical writing and/or PV experience Strong English verbal and written communication skills Strongly Preferred: Aggregate safety report writing and aggregate safety analysis Project management of safety/regulatory documents Awareness of applicable regulations and guidance related to post-marketing aggregate safety requirements Experience using Microsoft word templates Qualifications Bachelor s degree in health or biomedical science (3+ years industry experience or equivalent) or Advanced degree preferred in health or biomedical science (2+ years industry experience or equivalent) Additional Information All your information will be kept confidential according to EEO guidelines.
    $63k-92k yearly est. 60d+ ago
  • Scientist

    Stefanini_Training 4.6company rating

    Senior scientist job in West Chester, PA

    Stefanini Group is looking for Scientist - West Chester, PA · The Scientist in Clinical Pharmacology and Pharmacometrics will be involved in the clinical pharmacology (CP) strategy, planning, direction, execution and data analysis/interpretation of clinical pharmacology studies. · The incumbent will participate to the CP activities for one or more programs in the early development portfolio and may represent the CP department at internal meetings (study, project, clinical team). · In addition, the incumbent will participate in the CP sections in documentation submitted to the regulatory authorities and in any required communication or interaction such as replies regarding CP questions during submissions. · This candidate will apply model based drug development concepts to impact decision making and is expected to have experience and relevant training in pharmacokinetics/pharmacometrics. · Candidates with less experience will be paired with a supervisor and will bear less responsibilities at the program level. · This is a full time position, less than 40 hours a week can be discussed/negotiated. Permanent hire for the right candidate is a possibility, contract is a minimum of 1 year. Qualifications • Education: • PhD in pharmaceutical sciences/pharmacology or other relevant life sciences. • PharmD (clinical pharmacology background/experience). • Problem solving skills. • Demonstrated ability to work in a team environment. • Ability to work in a complex multi-disciplinary and global environment. • English proficiency with strong presentation and communication skills. • Interest in clinical pharmacology and in clinical research (designing/managing clinical studies and Good Clinical Practices). • Experience in PK and or population PK/PD analysis (Phoenix WinNonlin training preferred, other modeling software a plus). • Minimum 2-3 years prior experience (including any post-doctoral project with Universities, Pharma or regulatory agencies) • Less experience acceptable especially with strong technical or clinical pharmacology skills
    $72k-103k yearly est. 60d+ ago
  • Scientist

    Frontage Laboratories 3.9company rating

    Senior scientist job in Exton, PA

    Scientist/Sr. Scientist Division/Department: Analytical Services, CMC (Chemistry, Manufacturing, and Controls) Reports to: Manager/Group Leader Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Job Summary The Scientist or Sr. Scientist is responsible for supporting in vitro release Testing /In vivo Release testing on drug products. The scientist's duties include analytical method development/method validation, protocol/report writing, IVRT/IVPT apparatus maintenance and qualification. Role & responsibilities 1. Hands-on experience in conducting, planning and monitoring In-vitro skin permeation studies and Invitro Release Testing: IVPT/IVRT development, validation, pilot study and pivotal study. 2. Thorough knowledge and complete understanding on FDAs requirement for IVPT studies. 3. Data interpretation and day-to-day troubleshooting related to IVPT studies. 4. Should have experience in review of raw data and protocol/report preparation for development, validation, pilot and pivotal studies. 5. Adhere to compliance and regulatory requirement for in-vitro studies. 6. Implementation and revision of SOP's related to IVRT and IVPT studies. 7. Good Subject knowledge related to Bio-analytical methods/Bio samples analysis and interpretation of bioanalytical data. 8. To ensure routine calibration and preventive maintenances of IVRT and IVPT lab instruments within timelines. 9. Should have experience in writing justification and design of experiments to address Agency's deficiencies on IVRT and IVPT. 10. Review and preparation of all study protocols and reports. 11. Interaction with cross functional team and to meet the project timelines. 12. Comfortable handling and/or working with biological tissues such as human skin . 13. Follow company policies and conduct work according to appropriate Frontage SOPs and comply with GLP/cGMP guidelines. Essential Duties & Responsibilities Method development/Validation on IVRT/IVPT testing. Any other drug product testing work. Protocol/Report writing, Data Review. Educational/Training Requirement: bachelor's degree or above Experience: at least two years of related work experience Knowledge, Skills, and Abilities (KSAs): Clear communication, organization, and teamwork. Travel Requirements: 0% Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
    $59k-87k yearly est. Auto-Apply 60d+ ago
  • Scientist, Disease Modeling and Phenotyping

    Synapticure Inc.

    Senior scientist job in Philadelphia, PA

    About SynapticureAs a patient and caregiver-founded company, Synapticure provides instant access to expert neurologists, cutting-edge treatments and trials, and wraparound care coordination and behavioral health support in all 50 states through a virtual care platform. Partnering with providers and health plans, including CMS' new GUIDE dementia care model, Synapticure is dedicated to transforming the lives of millions of individuals and their families living with neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS. The RoleAs part of building the next generation of neurodegenerative care, Synapticure is investing in cutting-edge biological platforms to understand and treat ALS, FTD, and related diseases at the cellular level. We are developing a novel patient-derived disease modeling platform using in vitro systems to advance our ability to screen, diagnose, and develop therapeutics tailored to patient-specific biology. Our initial focus is ALS and FTD, but our long-term vision includes applications across a wide spectrum of neurodegenerative disorders. We are seeking a Scientist, Disease Modeling and Phenotyping who thrives at the intersection of hands-on laboratory work and computational biology. In this full-time, in-person role based in Philadelphia, PA, you will lead the development of high-throughput iPSC-based cell models and apply phenotypic screening approaches using advanced imaging, transcriptomics, and biochemical assays. Your work will directly support the discovery and advancement of new diagnostics and therapeutics for patients living with neurodegenerative diseases. You'll play a critical role in both the wet lab and analytical domains;developing screening protocols, executing experiments, and helping analyze and interpret complex datasets. This is a unique opportunity to contribute directly to the future of neurodegenerative disease research while collaborating with a cross-disciplinary team of biologists, neuroscientists, clinicians, engineers, and data scientists. If you're motivated by science with impact, this role offers the chance to make a real difference in patients' lives. Job Duties - What you'll be doing Design and execute phenotypic screening protocols for complex, cell-based assays using high-content imaging and transcriptomic readouts. Conduct hands-on wet lab work, including iPSC culture, differentiation, assay development, and imaging. Analyze and interpret multi-dimensional datasets including image-based screens and RNA-seq data. Collaborate cross-functionally to ensure data quality, reproducibility, and relevance to patient biology. Troubleshoot experimental workflows, including cell-line scale-up, instrument scheduling, and protocol optimization. Lead cellular screens at scale and contribute to the selection and onboarding of new technologies and methodologies. Ensure laboratory SOPs are followed and participate in lab operations, including inventory and process standardization.Maintain awareness of cutting edge disease-relevant and stem-cell modeling publications Requirements - What we look for in you PhD (or equivalent experience) in neuroscience, biomedical sciences, bioengineering, computational biology, or a related discipline. Strong experience with wet lab techniques, particularly iPSC culture, differentiation, imaging, qPCR, and protein assays. Interest or experience in basic computational biology or high-content data analysis. Excellent documentation, scientific communication, and project management skills. Ability to collaborate in a multidisciplinary environment and juggle multiple projects at once. Adaptability in a dynamic startup setting with a proactive, solution-oriented mindset. Preferred Qualifications Experience with transcriptomic or omics analysis (RNA-seq, single-cell). Proficiency in microscopy techniques, including immunohistochemistry, 3D imaging, and high-content imaging. Experience in neurodegenerative disease modeling. Familiarity with both 2D and 3D cell culture systems. Knowledge of automation, liquid handling, and/or high-throughput screening platforms. We're founded by a patient and caregiver. This means our values are at the heart of everything we do, and while we're located all across the country, these principles are what tie us together around a common identity: Relentless focus on patients and caregivers . We are determined to provide an exceptional experience for every patient we have the privilege to serve, and we put our patients first in everything we do. Embody the spirit and humanity of those living with neurodegenerative disease. Inspired by our founders, families and personal experiences, we recognize the seriousness of our patients' circumstances, and meet that challenge every day with empathy, compassion, kindness, joy, and most importantly - with hope. Seek to understand, and stay curious . We start by listening to one another, our partners, our patients and their caregivers. We communicate with authenticity and humility, prioritizing honesty and directness while recognizing we always have something to learn. Embrace the opportunity. We are energized by the importance of our mission, and bias toward action. Work Location: This position is in-person and based in our Philadelphia, PA laboratory.
    $63k-92k yearly est. Auto-Apply 28d ago
  • Formulations Scientist ( Staff Scientist ) - Near Philadelphia, PA / Wilmington, DE

    Hr Recruiting Solutions

    Senior scientist job in Wilmington, DE

    Must be authorized to work in the United States - No Sponsorship Experience required - 2 to 10 years of solid dosage experience (capsule or tablet) Our client is looking for a highly dependent person with PhD or MS and a passion for great formulation science. Here are a few key points: - Modern spacious lab to run projects - Working on a 8 person departmental team (New Grad to 20+ years of experience) - Global 10,000 person company so room to grow. - This role you will present results to senior management and attend sales presentation so well spoken and professional demeanor is important. - Someone who is customer service focused. - Everyone can attend a conference and top performers can attend several a year. Keywords: Solid dispersion, fluid bed, Spray dryers, Twin Screw Extruders, Solid dosage form, roller compactors, Granulators, Tablet presses, Fluid bed, Coaters, pharmaceutical, CRO, Medical Device, Characterize powders, disintegration, flowability, DSC, compactibility, density, particle size distribution, TGA , USP dissolution, crushing force, XRPD, friability Additional Information Equal opportunity employer. D/V/M/F. Applicants will be considered without regard to age, race, creed, color, national origin, ancestry, marital status, sexual orientation, gender identity or expression, disability, nationality, sex, or veteran status.
    $73k-109k yearly est. 7h ago
  • Associate Scientist I LCMS

    Alliance Pharma 3.9company rating

    Senior scientist job in Malvern, PA

    Responsibilities * Prepare reagents, standards, and control samples * Analyze samples using various techniques specific to department * Assist with method development * Perform method validation or qualification * Operate analytical equipment * Lead troubleshooting activities * Maintain analytical equipment * Ensure lab area is clean and inspection ready at all times * Remove lab waste * Record tasks in accordance with Good Documentation Practices (GDP) * Understand and apply regulatory requirements; GLP, GCP, 21CFR Part 11 * Follow applicable SOPs and procedural documents * Review and evaluate data results * Train lower level Scientists * Other tasks as assigned Education, Experience & Skills Required * BA/BS or higher with 5-6 years lab experience; all experiences will be evaluated * Able to perform complex lab work * Able to work in a regulated environment * Able to work effectively and contribute within a team * Able to work with computer systems * Able to document clearly; knowledge of and experience in a regulatory environment
    $55k-78k yearly est. 7d ago
  • Scientist

    Mindlance 4.6company rating

    Senior scientist job in Spring House, PA

    Mindlance is a national recruiting company which partners with many of the leading employers in the Life Sciences, IT, and Financial Services sectors, feel free to check us out at ************************* Job Description The successful candidate will be responsible for performing multiple biochemical assays to screen compounds and profile lead candidates for pharmaceutical targets. Job requirements include ability to work with purified proteins, compound plate creation and tracking and perform biochemical assays. The successful candidate will work as part of an interactive research team; will report results of studies back to team members and in a timely, thorough, and coherent manner. Such a position requires an energetic, highly organized and motivated person. Requirements include compound plate creation using dispensers such as ECHO, compound ordering and tracking, execution of biochemical assays using automated liquid handlers and spectroscopic readers and generation of electronic notebooks that document all performed work. Good communication skills as well as an aptitude to perform research activities in a collaborative and result-driven setting are a must. Qualifications The successful candidate will possess an M.S. with 1-3 years of experience or a B.S. /B.A. with 2-4 years of experience or the equivalent training/experience. Additional Information All your information will be kept confidential according to EEO guidelines.
    $65k-93k yearly est. 7h ago
  • Bioconjugation Scientist

    ZP Group 4.0company rating

    Senior scientist job in Philadelphia, PA

    Piper Companies is seeking a Bioconjugation Scientist to join a Biotechnology company located in Philadelphia, PA through an on-site, 6-month contract. The Bioconjugation Scientist will aid in developing innovative gene therapy treatments for significant life-threatening illnesses using conjugates. Responsibilities of the Bioconjugation Scientist include: * Design, organize, and perform experiments regarding bioconjugate synthesis * Execute protein/conjugate purification and characterization using modern separation techniques * Examine conjugates and biomolecules using LC-MS, HPLC, UV-Vis, SDS-PAGE gels, and RNA gels * Keep detailed records of experiments, outcomes and collected data in an electronic lab notebook * Work in partnership with chemistry, analytical, and biology teams to advance projects competently * Comply with company safety regulations and GLP guidelines Qualification for the Bioconjugation Scientist include: * Bachelor's or Master's degree in chemistry, biochemistry, or a related field; 1-3 years of practical lab experience related to bioconjugation, protein chemistry, or similar fields * Strong practical proficiency in bioconjugation chemistry working with oligonucleotide, peptide or small molecule conjugates using standard chemical and enzymatic conjugation methods * Possess knowledge regarding chromatographic purification and analytical characterization of large molecules such as proteins, antibodies and their conjugates * Knowledge regarding AKTA purification systems is very desirable * Ideal candidate will have independent work skills, the ability to multitask and be detail-orientated and a quick learner This job opens for applications on 01/14/2026. Applications for this job will be accepted for at least 30 days from the posting date. Compensation for the Bioconjugation Scientist includes: * Salary: $65,000-$70,000 annual * Direct Labor (DL) Rate: $33.65/hour ($70,000) * Includes 6 holidays and 10 days of PTO Keywords: bioconjugation, scientist, bioconjugation scientist, biotechnology, onsite, in-person, temporary, contract, contract to hire, bioconjugate synthesis, protein purification, conjugate purification, conjugate, protein, LC-MS, HPLC, UV-Vis, SDS-PAGE gels, RNA gels, ELN, chemistry, biology, in-lab, laboratory, lab experience, laboratory experience, biochemistry, protein chemistry, oligonucleotide, peptide conjugates, molecule conjugates, chemical conjugation, enzymatic conjugation, chromatographic purification, antibodies, AKTA purification systems #LI-TM1 #LI-onsite
    $65k-70k yearly 4d ago
  • Associate Scientist 1

    Weston Solutions Inc. 4.5company rating

    Senior scientist job in Gibbsboro, NJ

    At Weston Solutions, Inc. you will do meaningful work and make valuable contributions. Employee ownership at Weston is a path to professional growth and access to diverse opportunities in a highly connected community that works together across key service areas to make a difference in the environment. Weston has continued to evolve and adapt to our changing world as a premier provider of environmental and infrastructure services for over sixty years. In both the public and private sectors our teams help identify, solve, mitigate, and manage critical environmental issues to help clients achieve a more sustainable future. Weston Solutions, Inc. is actively seeking an Associate Scientist to provide technical support to project managers for our commercial, state, and federal projects. The candidate will perform field activities in support of permit applications and site investigation activities. Such field activities may include environmental sampling, site surveys, wetland and stream delineations, habitat assessment, restoration areas monitoring, and sub-contractor oversight. Additionally, the candidate will perform compilation of field data and assist with the preparation of technical reports and permit applications for a variety of environmental projects. Location: This role will primarily support projects in the northeast region (New Jersey, Pennsylvania, and New York) and candidates will be required to be located within 1 hour of Camden County, New Jersey Tasks will be conducted in the field and office work can be supported from home. Expected Outcomes: * Assists with wetland delineations/monitoring and remedial investigations (e.g., soil, sediment, groundwater, and surface water sampling) implementing methods and procedures in accordance with the scope of work. * Provides oversight of sub-contractors and documents field activities accordingly. * Compiles and evaluates field data and assists in technical report preparation. * Assists with preparation of permit applications, as requested, including review of applicable regulations. * Communicate with team lead and project managers regarding project tasks and progress. Knowledge, Skills & Abilities: * B.S. or B.A. in Environmental Science, Biology, Ecology, or related natural resource program. with 1-3 years of experience or a recent graduate with equivalent experience. * Ability/flexibility to travel and complete field work during the field season (April to October) and work extended hours. * Ability to work outdoors in variable weather conditions and on challenging terrain for an extended period. * Prior environmental consulting experience including wetland delineation, sampling environmental media, and/or federal, state, and local permitting is a plus. * Familiarity with the 1987 Army Corps of Engineers Wetland Delineations Manual and Regional Supplement(s). * Working knowledge of sub-meter accuracy GPS technologies and collection of digital data (e.g., ARC GIS Field Maps) is a bonus. * Wetland training/desire to obtain certifications (Professional Wetland Scientist, Wetland Professional in Training) is preferred. * Knowledge regarding State (NJDEP, PADEP, NYSDEC) and Federal (USEPA, USFWS, and USACE) regulations and permitting is a plus. * Experience recording field data, writing technical reports and building tables and spreadsheets. Proficient in the use of Microsoft Office and Adobe. Additional experience in GIS software and figure preparation is a bonus. * Ability to read and interpret engineering drawings is a plus. * Ability to complete office tasks and field work independently with minimal supervision. * Ability to maintain effective communication and productivity while working remotely. * Ability to collect site information from publicly available databases. * Ability to lift 40 pounds. * Valid driver's license and a good driving record. * 40-hour OSHA HAZWOPER certification a plus. We fully invest in our people: Weston provides a generous, comprehensive benefits package program that offers employees high value options with solid financial protection, meeting the personal needs of its people and their families. * Medical, Dental, Vision, 401K with base and matching employer stock contributions. * Paid time off including personal, holiday and parental leave. * Life and disability plans. * Critical illness and accident plans. * Work/Life flexibility. * Professional development opportunities. Compensation will vary based upon experience, education, skill level, and other compensable factors.
    $60k-81k yearly est. Auto-Apply 4d ago

Learn more about senior scientist jobs

How much does a senior scientist earn in Upper Darby, PA?

The average senior scientist in Upper Darby, PA earns between $67,000 and $130,000 annually. This compares to the national average senior scientist range of $74,000 to $153,000.

Average senior scientist salary in Upper Darby, PA

$93,000

What are the biggest employers of Senior Scientists in Upper Darby, PA?

The biggest employers of Senior Scientists in Upper Darby, PA are:
  1. Cisco
  2. Coriell Institute for Medical Research
  3. Legend Biotech
  4. Chubb
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