Post job

Principal research scientist jobs in Berkeley, CA

- 3,132 jobs
All
Principal Research Scientist
Research Scientist
Product Development Scientist
Scientist
Senior Scientist
Senior Research Associate Scientist
Research And Development Scientist
Senior Scientist, Biology
Senior Bioinformatics Scientist
Senior Formulation Scientist
PHD Researcher
  • Senior Machine Learning Scientist

    Expedia Group 4.7company rating

    Principal research scientist job in San Jose, CA

    Senior Machine Learning Scientist - Traveler Engagement & Loyalty team (San Jose) Introduction to the Team: Expedia Technology teams partner with our Product teams to create innovative products, services, and tools to deliver high-quality experiences for travelers, partners, and our employees. A singular technology platform powered by data and machine learning provides secure, differentiated, and personalized experiences that drive loyalty and traveler satisfaction. The Traveler Engagement & Loyalty team at Expedia is at the forefront of innovation in AI-driven recommendation systems. We're dedicated to enhancing customer experiences, increasing engagement, and strengthening traveler relationships through cutting-edge machine learning solutions. Our work directly impacts millions of travelers worldwide, shaping their journey from dreaming to booking and beyond. Join a newly formed Machine Learning Science team at Expedia Group focused on transforming Customer Relationship Management (CRM) through intelligent, personalized outbound communications. From crafting tailored travel recommendations to optimizing engagement strategies, your work will directly influence millions of travelers globally. This is a rare opportunity to build foundational systems in a high-impact domain, backed by Expedia's AI-first vision. In this role, you will: Build and optimize recommendation models for CRM use cases, including personalized email campaigns and retention strategies Apply deep learning and causal inference to sparse, noisy, and dynamic customer interaction data Design and analyze A/B experiments to validate model performance and drive product decisions Collaborate with ML Engineers to deploy models at scale, ensuring robustness and reliability in production environments Translate business objectives into measurable machine learning goals aligned with customer engagement outcomes Stay current with advancements in recommendation research, deep learning architectures, and personalization systems Mentor junior scientists and engineers, sharing best practices in ML modeling, experimentation, and deployment Minimum Qualifications: PhD, MS, or BS in Computer Science, Machine Learning, Statistics, Engineering, or a related field; or equivalent professional experience 8+ years of related industry experience Experience building production-grade recommendation or personalization systems Strong understanding of collaborative filtering, deep learning for recommendations, reinforcement learning, and causal inference Proficiency in Python and ML frameworks such as TensorFlow or PyTorch Experience with distributed systems like Apache Spark Familiarity with A/B testing and experimentation methodologies Ability to work with large-scale, real-world data with attention to bias, fairness, and privacy Excellent communication skills for both technical and non-technical audiences Preferred Qualifications: Experience in the travel or e-commerce industry Familiarity with cloud platforms (AWS, GCP, Azure) Publications in top-tier ML conferences or journals Contributions to open-source ML projects Experience in personalization systems or CRM-focused ML applications Experience taking models from prototype to production in collaboration with Machine Learning Engineering teams
    $153k-209k yearly est. 1d ago
  • Research Scientist

    Kadence

    Principal research scientist job in San Francisco, CA

    About the Company We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks. About the Role As a Research Scientist, you will develop new benchmarks, methodologies, and evaluation pipelines that shape how cutting-edge models are assessed, compared, and deployed in production environments. Your work will directly influence model selection and safety decisions across foundation model labs, high-growth AI product companies, and Fortune-scale enterprises. Responsibilities Benchmarking & Model Analysis Evaluate newly released models as they launch (e.g., Gemini, DeepSeek, etc.) Run large-scale assessment workflows using internal evaluation infrastructure Compare model performance across enterprise-grade task categories Design New Benchmarks from Scratch Identify high-value model application domains through research exploration Construct datasets, including labeling strategy and workforce coordination Write short “white-paper-style” summaries explaining benchmark purpose, method, and findings Advance Automated Evaluation Methodologies Improve systems for scoring generated text beyond standard metrics Explore research in reference-free, rubric-based, and human-aligned evaluation Develop new techniques for reliability, consistency, and repeatability Cross-functional Collaboration Work closely with engineering to scale evaluation infra Partner with customers to refine evaluation relevance and task fit Influence product direction through research insights Qualifications 0-3 years post-grad experience (Master's, PhD, or equivalent applied research) Publications, preprints, or demos showing cutting-edge work Experience with diffusion models, NLP, multimodal, or benchmarking work Ability to operate independently with ambiguity Clean, maintainable research codebases Candidates from: top engineering/research universities applied AI startups well-regarded research internships Required Skills Built or contributed to a benchmark or evaluation methodology Experience in enterprise task model evaluation Stanford / top lab adjacency (per their historical hiring success) Preferred Skills Wants to publish as primary motivation Purely academic with slow timelines Big-tech culture fit concerns (Meta / Google / Salesforce specifically noted-but case-by-case) Pay range and compensation package Base Salary: up to $250K depending on background Equity: typically 0.3% - 0.5%, flexibility for exceptional candidates Rapid equity refresh possible based on impact Equal Opportunity Statement Visa sponsorship available. Relocation support. Health & dental coverage. Lunch + dinner provided, snacks & coffee. Unlimited PTO. Weekly happy hours with community guests. Team events (bowling, hiking, rock climbing, etc.). Swag program (hats, etc.). Work Environment & Culture In-person, San Francisco HQ (required). Core hours: 9-5, some teammates extend voluntarily. Most team members work 1 weekend day per week (flexible). High-ownership, low-ego, collaborative. Live demos Mondays, team lunch Thursdays, community Fridays. Early-stage pace, applied focus-not academic publishing. Tech Environment (while research-focused, exposure beneficial) Backend: Python / Django. Frontend: React + TypeScript. Infra: AWS. Evaluation frameworks + internal tooling. Why This Role Is Unique The company already collaborates with foundation model labs, high-growth AI vertical product companies, and Fortune 500 enterprises (not publicly facing). ChatGPT Vals AI $5M seed raised, runway of 2+ years at current burn. Only one research scientist is being hired-true founding impact. Opportunity to define industry standards for model trust, reliability, and certification. Positioned to become the rating agency for generative AI.
    $250k yearly 1d ago
  • research scientist - RL

    Cerebro 3.3company rating

    Principal research scientist job in San Jose, CA

    Join a Leading Applied Research Lab Pushing the Boundaries of Reinforcement Learning Are you passionate about advancing the frontiers of reinforcement learning (RL)? An innovative AI research lab is seeking talented and ambitious scientists to shape the next generation of RL techniques-especially where they intersect with large models and environment generation. About the Role As an AI Research Scientist focused on RL, you will: Develop novel optimization-based methods for automated RL environment generation Establish baselines for evaluating the quality and diversity of RL environments Design infrastructure to create dynamic environments from historical datasets and agent evaluations Drive your own research agenda, contributing directly to the progress of our platform and the broader AI community What We're Looking For PhD (or equivalent experience) in machine learning, computer science or a related field Strong publication record and/or evidence of research impact (open source, deployed systems, etc.) Deep expertise in reinforcement learning and machine learning fundamentals Proficient in Python and at least one modern ML framework (such as PyTorch or JAX) Bonus Points Experience with post-training large language models (LLMs) Demonstrated software engineering skills Ability to communicate research findings effectively to both technical and non-technical audiences
    $150k-251k yearly est. 5d ago
  • Research scientist (Robotics, AI)

    Intellipro 4.3company rating

    Principal research scientist job in Santa Clara, CA

    Job Title: Research scientist (Robotics, AI) Position Type: Full-Time / Permanent Salary range: $200,000/yr - $270,000/yr Job Description: We are an early-stage robotics startup working on building multi-purpose mobile robots that can do complex manipulation tasks. We are looking for a creative, skilled, and motivated research scientists to join our founding team in advancing robot manipulation capabilities. We are looking for people with proven expertise in machine learning and/or robotics. You will collaborate with a team of talented researchers and engineers, and drive ongoing innovation and technological advancements within the company. This is a full-time on-site role in Santa Clara, CA. Responsibilities: Develop new algorithms and methods for training AI models for enhancing the robot dexterity. Conduct cutting edge research across multiple disciplines (Robotics, RL/IL, control, perception, LLM, VLM, etc.). Work with large-scale ML systems and large-scale model training/fine-tuning. Design and implement state-of-the-art learning-based manipulation/navigation/control algorithms on real robots. Work with other teams to develop a diverse set of robust manipulation skills for robots. Requirements: Ph.D. degree in Robotics, Computer Science/Engineering, Electrical Engineering, Mechanical Engineering, etc., or equivalent research experience. Passionate about working with robots and building robot products. Excellent analytical, problem-solving, and communication skills. At least 3 years of experience conducting independent research. Deep understanding of the SOTA robot learning techniques (reinforcement learning, imitation learning, etc.) A track record of research excellence with your work published in top conferences and journals such as Science Robotics, IJRR, RSS, CoRL, ICRA, NeurIPS, ICML, ICLR, CVPR, etc. Proficient with Python. Proficient with deep learning libraries such as PyTorch/TensorFlow/Jax. Experience with real robot experiments. Experienced with robot simulators such as Isaac Gym/ Isaac Sim/ SAPIEN/ MuJoCo/Drake, etc. About Us: Founded in 2009, IntelliPro stands as a global leader in talent acquisition and HR solutions. Our commitment to delivering unparalleled service to clients, fostering employee growth, and building enduring partnerships sets us apart. With a dynamic presence in the USA, China, Canada, Singapore, Philippines, UK, India, Netherlands, and Germany, we continue to lead the way in global talent solutions. IntelliPro is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We also ensure that all applicants have access to accommodations throughout the hiring process. Learn more at *************************** Compensation: The compensation offered will depend on various factors, including location, experience, education, and job-related skills. This role includes a competitive base salary, bonus, equity, and a comprehensive benefits package, subject to eligibility.
    $200k-270k yearly 3d ago
  • Research Scientist

    Goliath Partners

    Principal research scientist job in San Mateo, CA

    We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring a Research Scientist on a hybrid basis. They have seen $300M in a recent fund raise. Skills targeted: PhD in Physics/ Quantum Physics/ Theory/ Statistics/ Mathematics/ Computational Science or similarly related field. 2+ YoE working with AI Agents. Good exposure to LLMs. Ideally a background in Audio focused research. Alternatively Search, would also be highly advantageous. TC package of $1-1,5M with sizeable base salary & equity package. If that looks of interest, apply & Goliath will be in touch!
    $96k-161k yearly est. 1d ago
  • Research Scientist - Vision Data Infrastructure

    Storm3

    Principal research scientist job in San Francisco, CA

    Research Scientists/Engineers (all levels) 🔍 Focus on Vision Data Infrastructure 🤖 Fundamental AI Research Institute 🌎 San Francisco Bay Area, USA 💸 $250,000 - $600,000 salary + annual bonus Come join one of the only research institutions globally with resources to compete with top AI companies =>10s of 1000s of GPUs to explore state-of-the-art research in LLMs, Multimodal and Agentic AI. Currently seeking AI talent with expertise in building scalable pipelines for vision data to support both image/video generative training and multi-modal alignment. You'll design high-performance pipelines for large-scale image and video datasets, enabling efficient pretraining, alignment, and simulation-based data generation. Responsibilities: Vision Data Sourcing & Curation Collect and organize image and video data from open datasets and the web. Handle data cleaning, filtering, deduplication, and metadata generation. Ensure ethical and compliant data collection at scale. Processing & Augmentation Build high-throughput pipelines for vision data preprocessing (frame extraction, resolution normalization, format conversion, latent caching). Implement GPU-accelerated augmentation and distributed data loading (WebDataset, TFRecords, Parquet). Synthetic & Simulation-Based Data Generation Use simulation tools (e.g., Unreal Engine 5, Isaac Sim, Unity) to generate high-quality synthetic vision data. Create specialized datasets for VLM training, visual reasoning, and agent interaction. Requirements: Strong experience with data engineering, computer vision, or machine learning infrastructure. Expertise in building and scaling ETL/data pipelines for large unstructured datasets. Proficiency with Python, PyTorch, and distributed data frameworks (e.g., Ray, Spark, Dask). Experience with WebDataset, TFRecords, Parquet, or similar high-throughput data formats. Familiarity with GPU-accelerated preprocessing, NVIDIA DALI, or equivalent systems. Understanding of image/video codecs, data compression, and cloud storage optimization. Preferred Experience: Prior work with simulation-based or synthetic data generation using Unreal Engine, Isaac Sim, or Unity. Experience curating datasets for multimodal or vision-language model training. Knowledge of data ethics, privacy, and compliance frameworks for large-scale AI datasets. Experience contributing to open datasets or data-centric AI research. Why apply: Opportunity to join a fast-growing core team that are already pushing AI breakthroughs Highly competitive salary package Work alongside ambitious and bright superstars from tech and academia Medical, Dental and Vision Insurance Relocation package available 🌎 San Francisco Bay Area, USA 📧 Interested in applying? Please click on the ‘Easy Apply' button or alternatively email me your resume at ************************
    $95k-160k yearly est. 2d ago
  • Senior Applied Scientist

    Alibaba.com

    Principal research scientist job in Sunnyvale, CA

    About our team: Our team is dedicated to revolutionizing B2B e-commerce through the development of a groundbreaking AI search product. Leveraging cutting-edge LLM technology, we're creating a brand new AI search engine and streamline the entire purchasing process for B2B customers. Responsibilities ● Deliver full projects by defining the data structure, framework, design, and evaluation metrics for AI solution development and implementation. ● Develop and deploy Large Language Models (LLMs) to empower search and agent systems for a variety of applications. ● Identify new and upcoming product innovation areas by interacting with potential external and internal collaborators. ● Identify undefined problems in existing technology and engage stakeholders and leaders to address them. Qualifications ● PhD, Master's, or Bachelor's degree in Computer Science, Engineering, Mathematics, or related fields. ● Ability to implement and verify state-of-the-art NLP or Computer Vision algorithms. ● Experience in successfully applying machine learning approaches to real-world personalization problems. ● Experience with building large language models. ● Knowledge of statistical methods, with strong mathematical skills. ● Excellent problem-solving and programming skills in Python. The pay range for this position at commencement of employment is expected to be between $162,400/year and $266,000/year. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
    $162.4k-266k yearly 1d ago
  • AI/ML Scientist

    Saragossa

    Principal research scientist job in San Mateo, CA

    AI/ML Scientist - Build the Future of Physics AI- $250,000 to $275,000 Salary You will be part researcher, part builder, part pioneer, someone who thrives at the intersection of machine learning and physics based simulation. The platform is built on massively scalable, cloud native simulation technology that makes it possible to run thousands of high fidelity simulations quickly and easily. This foundation unlocks something big, enabling the generation of large scale datasets that power the next generation of ML models across industries. You will be on the front lines of building and productizing new machine learning approaches for physics based problems, from CFD to thermal simulation. Your work will not just live in a paper, it will deliver measurable value to customers, shape new product capabilities, and push the boundaries of what is possible in Physics AI. You know that rush when your work goes from experiment to production, when the models perform, the results hold up, and you can see the impact firsthand? That is what this role is about. Ready to shape the future of Physics AI? Let's talk. No up to date resume required.
    $250k-275k yearly 2d ago
  • Founding Applied Research Scientist (RL)

    Greylock Partners 4.5company rating

    Principal research scientist job in San Francisco, CA

    Early-stage (vertical RL) company looking to hire a Sr. Applied RS with a strong background in reinforcement learning. Qualifications: Applied Research with MS or PhD in a related field and 4 + years industry experience in deep learning and 2+ years with reinforcement learning Successful track record as a self-starter in 0->1 scenarios with a proven ability to take SOTA models into production Please note: Due to the selective nature of this service and the volume of applicants we typically receive from our job postings, a follow-up email will not be sent until a match is identified with one of the startup investments in our portfolio. About Us: Greylock is an early-stage investor in hundreds of remarkable companies including Airbnb, LinkedIn, Dropbox, Workday, Cloudera, Facebook, Instagram, Roblox, Coinbase, Palo Alto Networks, among others. More can be found about us here: ********************* We are full-time, salaried employees of Greylock who provide free candidate referrals/introductions to our active investments to help them grow/succeed (as one of the many services we provide). Please note: We are not recruiting for any roles within Greylock at this time. This job posting is for direct employment with a startup in our portfolio.
    $119k-187k yearly est. 4d ago
  • Senior RL Research Scientist

    Deeprec.Ai

    Principal research scientist job in San Francisco, CA

    Senior RL Research Scientist / Reinforcement Learning Scientist Join a frontier AI team building systems that can act in the physical world, experimenting, optimizing, and controlling real processes through advanced ML, simulation, and automation. This group is pushing the boundaries of physical intelligence, backed by significant long-term funding and a mandate to invent from first principles. If you want to: Work on problems few teams in the world can touch Build RL systems that power real tools, workflows, and scientific processes Operate in a fast, high-ownership, deeply technical culture …this is the kind of role that defines a career. The Role You'll design and deploy reinforcement learning systems that control complex tools, optimize multi-step processes, and operate across high-fidelity simulations and digital twins. Expect hands-on research, real-world experimentation, and tight collaboration with teams across ML, simulation, and systems engineering. What You'll Do Build RL environments for tool control, workflow optimization, and long-horizon decision-making Develop safe and constrained RL methods, verifier-driven rewards, and offline to online training pipelines Create state/action representations and evaluation frameworks for reliable policy behavior Work with cross-functional researchers and engineers to deploy RL agents into real workflows What You Bring Strong background in RL, optimal control, or sequential decision-making Experience applying RL to complex simulated or physical systems Familiarity with safe/constrained RL, verifiers, or advanced evaluation pipelines Ability to design environments, rewards, and diagnostics at scale Comfort working across ML, simulation, and systems interfaces
    $118k-189k yearly est. 3d ago
  • Senior RL Research Scientist

    Acceler8 Talent

    Principal research scientist job in San Francisco, CA

    💡 What if your next role let you design reinforcement learning systems that directly control real-world science -training agents that run experiments, tune physical tools, and accelerate discovery from months to days? 🚀 Our client - a hyper-talent-dense physical-AI startup backed by top-tier builders across frontier AI and deep tech - is hiring a Senior RL Research Scientist (San Francisco / Redwood City, In-Person). They're building Physical Superintelligence: AI that can ask any scientific question about the physical world and get a real answer in days, not years-by pairing large models with massive automated “experiment factories.” The role: 🎯 Own RL for real-world tool control and long-horizon workflows across biology, chemistry, materials, and robotics 🧪 Build RL environments grounded in physics, simulation, and digital twins-not toy benchmarks 🛡️ Design safe / constrained RL + verifier-integrated rewards to keep agents reliable in high-stakes domains 📈 Drive offline → online transitions and evaluation pipelines as agents learn from and act on real telemetry 🤝 Partner across LLM, agent systems, simulation, and physical-tooling teams to deploy policies into production workflows ⚙️ High-ownership algorithm + systems work where you shape the foundations of physical-AI autonomy Why join? 🌍 Work at the frontier of real-world impact-from multi-cancer early detection to general scientific discovery 🏭 Operate on a uniquely scaled platform: 20k+ sq ft automated facilities producing real experimental feedback loops 💰 Competitive salary + meaningful equity 🚀 Tiny, world-class team with a “best-person-you've-worked-with” talent bar 🏢 In-person, high-velocity environment with deep collaboration across SF + Redwood City 📩 Interested? Apply now
    $118k-189k yearly est. 1d ago
  • Scientist/Sr. Scientist-Stem Cell Biology/Embryology

    Commonwealth Sciences, Inc.

    Principal research scientist job in San Francisco, CA

    located in San Francisco, CA Responsibilities of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology: Design and execute experiments in stem cell differentiation, organoid generation, and tissue engineering. Innovate then execute experiments to generate and differentiate human stem cells, develop functional assays, assess and interpret experimental workflows Perform mammalian embryo dissections, tissue isolations, and culture experiments to study and model developmental processes. Apply principles of developmental biology and embryology to guide tissue maturation and patterning. Collaborate with biomaterials and engineering teams to integrate cells and tissues. Develop and optimize protocols for reproducible tissue generation and maintenance. Test novel stem cell culture conditions, sort, screen, expand and differentiate hi PSCs according to latest protocols and newly developed approaches. Requirements of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology: PhD in biological sciences, stem cell biology, genetics or related field. 2+ years hands-on expertise in stem cell culture (iPSCs/ESCs). Hands-on experience with mammalian embryos, including dissections and culture. Experience in molecular biology and strong problem solving skills.
    $93k-152k yearly est. 5d ago
  • Scientist: In Vivo Pharmacology

    Proclinical Staffing

    Principal research scientist job in Palo Alto, CA

    Scientist, In Vivo Pharmacology - Permanent - Palo Alto, CA Where curiosity meets purpose-join us in shaping the future of science. Primary Responsibilities: Proclinical is seeking a highly motivated, dynamic Scientist to support in vivo research on our cutting-edge pipeline and discovery programs. You will be involved in the preparation and execution of murine animal experiments and the collation of data. The Scientist of In Vivo Pharmacology will: Preparation for and execution of translational experiments such as in vivo pharmacology and disease model experiments, including experiments in knockout and transgenic mice Animal handling during murine experiments, and handling of murine tissues resulting from animal experiments Management of relationships with third-party vendors on mouse breeding and shipping Identification, ordering, organization, storage, and proper disposal of laboratory reagents required for studies In collaboration with the Laboratory Biology team, aid in maintaining laboratory space and inventory Recording and filing data, preparing technical reports, and study summaries Report progress of projects in a timely and concise manner to supervisor May independently lead the development and implementation of new assays to support research projects; may independently execute experiments and perform data analyses of moderate complexity; may have responsibility for specific method or study. Occasionally provides assistance to and/or mentoring other technical staff, new research staff or interns Manages personal experimental timelines to meet project and personal goals Presents findings at the scientist, department, and site-level. Function as part of a collaborative team to support research needs Contribute to the optimal functioning of the research team, including implementation of new tools and technologies. Skills & Requirements: S. and 7+ years of laboratory experience (academic and/or industry) or M.S. with 5+ years of laboratory experience (academic and/or industry) Degree must be in a life sciences discipline, preferably cellular and/or molecular biology, biochemistry, and/or microbiology/immunology 3+ years of hands-on experience with in vivo murine research required, with mouse pharmacology and inflammation disease model experiments highly desired Experience in experimental techniques such as handling of animal tissue, cell culture, qRT-PCR, flow cytometry, and ELISAs/MSDs is required Experience in immunology research, including research with primary immune cells, would be valuable Must be highly organized, punctual, and precise both in regards to performing laboratory experiments as well as maintenance of the laboratory space. Ability to work independently and occasionally during non-traditional work hours as may be required by some experiments and will need to be comfortable in a laboratory and animal facility setting. Possesses effective problem-solving, organizational, and communication skills Experience with Microsoft software suite (Word, Excel, PowerPoint), and other commonly used computer applications (Zoom, MS Teams, Box, etc.) Clear and effective communicator across verbal, written, and interpersonal settings If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page. Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy. By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - https://www.proclinical.com/privacy-policy
    $104k-165k yearly est. 5d ago
  • Senior Research Scientist, Biophysics

    Yoh, A Day & Zimmermann Company 4.7company rating

    Principal research scientist job in South San Francisco, CA

    Yoh is looking for a skilled and driven Senior Research Scientist, Biophysics with hands-on experience in small molecule drug discovery to join our collaborative Lead Discovery team. This is a lab-based role focused on the biophysical and mechanistic characterization of small molecule-protein interactions to support our drug discovery pipeline. This candidate must have hands on experience with designing and executing binding characterization studies using SPR. Industry: Discovery and Development Location: South San Francisco, CA Key Responsibilities: Design and execute binding characterization studies using SPR (Biacore S200 and 8K+). Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nano DSF, DLS, Spectral Shift). Manage and coordinate outsourced biophysical studies with CROs. Analyze and interpret data to support SAR and lead optimization across multiple projects. Maintain detailed experimental records and present findings in internal meetings and reports. Qualifications: PhD in Biophysics, Biochemistry, or a related field. Minimum 3 years of relevant industry experience in small molecule drug discovery biophysics. Proven expertise in SPR assay development and data interpretation. Demonstrated expertise in designing, developing, and interpreting biophysical characterization of small molecule-protein interactions by SPR. Strong familiarity with additional biophysical techniques (TSA, DLS, Spectral Shift, NMR, ITC, etc.). Proficiency with data analysis and graphing tools is a plus. #IND-SPG Estimated Min Rate: $70.00 Estimated Max Rate: $80.00 What's In It for You? We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh's network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh's extensive talent community that will provide you with access to Yoh's vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include: Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week) Health Savings Account (HSA) (for employees working 20+ hours per week) Life & Disability Insurance (for employees working 20+ hours per week) MetLife Voluntary Benefits Employee Assistance Program (EAP) 401K Retirement Savings Plan Direct Deposit & weekly epayroll Referral Bonus Programs Certification and training opportunities Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply. Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit ************************************************ to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh's hiring clients' preferences. To learn more about Yoh's privacy practices, please see our Candidate Privacy Notice: **********************************
    $70 hourly 3d ago
  • Decision Scientist

    Fractal 4.2company rating

    Principal research scientist job in Sunnyvale, CA

    Senior Decision Scientist Fractal is a strategic AI partner to Fortune 500 companies with a vision to power every human decision in the enterprise. Fractal is building a world where individual choices, freedom, and diversity are the greatest assets. An ecosystem where human imagination is at the heart of every decision. Where no possibility is written off, only challenged to get better. We believe that a true Fractalite is the one who empowers imagination with intelligence. Fractal has been featured as a Great Place to Work by The Economic Times in partnership with the Great Place to Work Institute and recognized as a ‘Cool Vendor' and a ‘Vendor to Watch' by Gartner. Please visit Fractal | Intelligence for Imagination for more information about Fractal Position Overview: Fractal is looking for a proactive and driven Senior Decision Scientist to join our Decision Science Consulting team in the San Francisco, CA area. In this role, you will help power measurable outcomes for leading technology organizations, leveraging cutting edge GenAI, Data Science, Engineering and Behavioral Science capabilities This is a perfect opportunity for someone, who is looking to combine best-in-class data science and analytics skills, strong problem-solving, effective communication and thought leadership to help our clients solve their most strategic business problems Responsibilities: Drive business decision making by deeply analyzing clickstream and other structured data, building machine learning/ statistical models to uncover actionable insights, and developing presentations to communicate the findings and recommendations Manage project roadmap by discussing potential analytics ideas, prioritizing based on estimated benefit vs. effort, documenting and planning for risks and blockers and periodically sharing status updates Contribute to the analytical foundations by documenting data and business understanding, sharing knowledge with broader team and coming up with new opportunities such as automating repetitive tasks, researching and applying new approaches/ techniques and bringing in ideas from other disciplines such as consumer psychology, brand, economics, competitive analysis, etc. Qualifications: Bachelors or equivalent experience in statistics, computer science, engineering, informatics, data science, or related field; additional business degree is a plus 8+ years of data science/ analytics experience with demonstrable hands-on expertise 3+ years of leading complex projects working with (or supervising) analysts, data scientists, AI engineers, designers, etc. Familiarity or natural interest towards management activities (project management, product management, team management) is strongly preferred Excellent communication and presentation skills are a must Strong proficiency with data manipulation is required (SQL + Python) Strong familiarity with ML development and testing in Python is required Must display strong learning agility to know the latest and greatest techniques across Statistics, ML and GenAI (Preferred) Demonstrated experience working with digital marketing functions e.g. purchase funnel optimization, digital product enhancement, email/ push marketing, etc. Hands-on experience in one, or more of the following is strongly preferred: regression, classification, clustering, time series forecasting, NLP Familairity with Adobe Analytics and Snowflake is a plus Salary Range: $130,000 - $155,000 (bonus and benefit eligible) Fractal provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
    $104k-149k yearly est. 4d ago
  • Scientist II

    Ultimate Staffing 3.6company rating

    Principal research scientist job in Oakland, CA

    Pay Rate Range: $50.00/hr. - $55.24/hr. Target Pay Rate: $55.24/hr. Duration: 3 Months Onsite Shift (if applicable): M-F 8:00 AM - 5:00 PM JOB DESCRIPTION SUMMARY/JOB PURPOSE: The Scientist II will be joining the Biotherapeutics Translational Pharmacology team to support our research programs. This position is primarily responsible for developing, optimizing and reporting out data for Bioanalytical assays for Antibody Drug Conjugates (ADC) to include ELISA, LC-MS and hybrid LC-MS techniques. This job will require the candidate to have excellent organization, communication, and teamwork skills, as well as flexibility and versatility, to meet tight deadlines in a dynamic, fast-moving environment. ESSENTIAL DUTIES AND RESPONSIBILITIES: * Responsible for running analytical samples from nonclinical PK studies using ELISA, LC-MS and hybrid LC-MS techniques * Operation and troubleshooting of automated instrumentation * Collaborates with Biotherapeutics team members to support project advancement. * Maintains electronic laboratory notebook in a complete, consistent, and timely manner in accordance with company intellectual property policies and practices. * Prepares and organizes data for presentation. May present data and status reports at individual, group, and departmental research meetings under general supervision. * Adherence to excellent health and safety practices and compliance with applicable EH&S safety rules and participates in mandatory safety training programs. * Other responsibilities as assigned SUPERVISORY RESPONSIBILITIES: * No supervisory responsibilities EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: Education: * Bachelor's degree in related discipline and a minimum of four years of related experience; or * Master's degree in related discipline and a minimum of two years of related experience; or, * Equivalent combination of education and experience. Experience: * Drug discovery experience is necessary with hands-on bioanalytical assay development with an excellent understanding of fundamental processes. * Experience with ELISA, LC-MS and Hybrid LC-MS is required * Experience using WinNonlin and PRISM applications are preferred. Knowledge/Skills: * Highly self-motivated with exceptional attention to detail is required. * Thorough knowledge of activities related to bioanalytical assay development and data generation * Excellent verbal and written communication skills with the ability to follow written instructions and SOPs. * Ability to multi-task and excellent time management skills. * Excellent work ethic, working effectively in both a team environment and independently. * Thorough proficiency in MS Word, MS PowerPoint and MS Excel is required. WORKING CONDITIONS: * Primarily working in laboratory and office environment. * Potential handling of hazardous materials, and brief periods of working in both 4°C and -20°C environments. * May be required to work weekends as needed. All qualified applicants will receive consideration for employment without regard to race, color, national origin, age, ancestry, religion, sex, sexual orientation, gender identity, gender expression, marital status, disability, medical condition, genetic information, pregnancy, or military or veteran status. We consider all qualified applicants, including those with criminal histories, in a manner consistent with state and local laws, including the California Fair Chance Act, City of Los Angeles' Fair Chance Initiative for Hiring Ordinance, and Los Angeles County Fair Chance Ordinance. For unincorporated Los Angeles county, to the extent our customers require a background check for certain positions, the Company faces a significant risk to its business operations and business reputation unless a review of criminal history is conducted for those specific job positions.
    $50-55.2 hourly 5d ago
  • Product Development Scientist

    Notco

    Principal research scientist job in San Jose, CA

    We are a group of people united by a strong purpose. We want you to get to know us, and Giuseppe, our very own artificial intelligence. We love good food, but above all, we love the planet, and that's why, to protect it, we reinvent the food industry, one delicious bite at a time, elevating what we eat, through our technology and based on plants. Our recipe has three mega-important components: science, technology, and of course, disruptive talents who work daily to create a better future. At NotCo we are not and do not seek to be the perfect company, but rather the right one. We are here to produce changes, and that is why we dare, fail, and sometimes achieve incredible successes. We are currently looking for a Product Development Scientist for our NotCo B2B Research & Development located in San Francisco, California, requiring an active on-site presence. This position will report to our R&D Sr. Team Lead and the incumbent will work cross-functionally to ensure R&D activities are successfully deployed locally. Responsible for the: Independently conducts day-to-day product development activities as directed by the manager across multiple projects. This includes supporting activities related to the full product lifecycle process (from product concept to successful commercial launch as needed)and supporting process development, scale-up and technology transfer Supports the design and execution of bench-top tests, pilot-plant trials and full-scale formulations to deliver high-quality food products that meet and exceed the sensory, cost, and other performance targets Proactively proposes and uses sensory and analytical analysis to guide and validate the development process Maintains detailed documentation, experiment tracking and outcomes, and documents finished goods and ingredient specifications Provides feedback to project lead regarding relevant technical and process information Communicates proactively and effectively with cross-functional teams, clearly articulating perspectives and trade-offs related to new product development goals Utilizes NotCo's proprietary AI technology to develop and improve food products Supports formula validation activities as well as process development, scale-up and technology transfer Engages in client communications and workshops, bringing technical Maintains detailed documentation across all R&D activities in a timely manner Qualifications / Requirements: Bachelor's degree in Food Engineering, Food Science, Engineering in Biotechnology or a similar discipline. 2 + years of Food R&D experience is desired, preferably across both food and beverage categories. Be agile, adaptable, and thrive in a dynamic and changing culture; works relentlessly to overachieve, anticipate obstacles, and create plans to overcome them. Adapts easily to changing priorities and direction based on new project learnings and team priorities. Demonstrated competency to effectively communicate (oral & written) cross-functionally with solid collaboration skills. Comfortable in client-facing situations and able to communicate complex topics clearly and simply. Excel in a startup environment, is excited to create new procedures and processes from scratch and has a strong entrepreneurial mindset. Be a problem solver, have a general manager mindset, and take the initiative to get the job done Possess strong planning, project management, and execution skills, and the ability to articulate where and how you have used them. Rigorous data-driven/analytical capability and ability and presence to present data effectively to a leadership team Work well in teams and cross-functional groups in a matrixed environment, both regionally and globally Possesses strong computer skills, including a high level of proficiency in MS Office, specifically Excel Authorization to work in the U.S. is required Ability to travel up to 50% of the time, including international travel and extended trips. NotCo is committed to fair and equitable compensation practices. The pay range for this role is $65,000 - $75,000. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. We are an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
    $65k-75k yearly 2d ago
  • Postdoctoral Researcher

    University of California, San Francisco 4.6company rating

    Principal research scientist job in San Francisco, CA

    The University of California, San Francisco (UCSF) is dedicated to advancing health worldwide through innovative research, high-quality education, and exceptional patient care. UCSF is recognized for fostering collaboration among its renowned graduate schools, medical center, and research programs. The university is committed to excellence, driving breakthroughs that improve lives. UCSF serves as a hub for scientific discovery and education in the heart of San Francisco, CA. The position is in the group of Drs. Boris Bastian and Iwei Yeh at UCSF's Helen Diller Family Comprehensive Cancer Center, leaders in melanoma genetics and translational research. The lab offers a stimulating, collaborative environment with access to cutting-edge technologies and interdisciplinary expertise. Role Description This is a full-time, on-site role for a Postdoctoral Researcher based in the Melanoma Discovery Lab at the University of California, San Francisco (UCSF) is seeking a highly motivated postdoctoral fellow (MD or PhD) to study systemic immune responses to gene fusion-driven cancers. This project explores how potent oncogenic fusions can initiate neoplastic growth while simultaneously triggering immune surveillance, with Spitz tumors serving as a model. The broader aim is to understand how similar transient, immune-contained lesions may arise in other tissues and be eliminated before clinical detection. The fellow will join a collaborative effort between cancer geneticists/melanoma biologists and genetic immunologists, combining genomic and immunologic approaches to study the systemic response to fusion-driven neoplasms. Qualifications MD or PhD in cancer biology, immunology, genetics, or related fields Strong research background and publication record Experience with molecular, genomic, or immunologic methods preferred Intellectual curiosity about tumor-immune system interactions Proficiency in Laboratory Skills and experience in conducting hands-on experimental work Strong Research and Data Analysis capabilities with attention to detail Experience with publication in peer-reviewed journals is a plus To Apply Send a CV, brief statement of research interests, and contact information for three references to **********************.
    $63k-81k yearly est. 2d ago
  • Product Development Scientist (Ph.D.) - College

    Clorox 4.6company rating

    Principal research scientist job in Pleasanton, CA

    Clorox is the place that's committed to growth - for our people and our brands. Guided by our purpose and values, and with people at the center of everything we do, we believe every one of us can make a positive impact on consumers, communities, and teammates. Join our team. #CloroxIsThePlace Your role at Clorox: The Research and Development organization is embedded within each of our Clorox businesses, taking new generations of consumer products from concept to reality. With such diverse roles as engineers, scientists, packaging experts, and technicians R&D is a community of technical leaders and managers actively involved in virtually every step in the lifecycle of our products, from initial concept to raw materials to final goods on store shelves. R&D is committed to leveraging the latest technology to bring consumers the high-quality, innovative products they expect and deserve. In this role, you will: As an R&D Product Development Scientist 2 at Clorox you will play a pivotal role in driving technical excellence and ensure superior product innovation across our Consumer Products and Professional Products portfolios. You'll apply your PhD-level expertise to develop and optimize product formulations that meet the needs of diverse end users from everyday consumers to hospital disinfection. Collaborating cross-functionally with teams in Marketing, Sales, Insights, Microbiology, Analytical Chemistry, and Digital Data, you'll translate scientific insights into impactful product solutions. You'll make a difference from day one, contributing to products used by millions of people while growing your technical and leadership skills working on some of the most trusted brands in the consumer goods industry. In this role you will: Drive Innovation: Develop and refine novel product formulations that deliver a superior product experience, while also creating consumer and customer facing claims and demos Execute with Excellence: Troubleshoot formulation challenges and make relevant measurements to generate data that supports technical solutions and translates them into business impact, while maintaining product specifications, formulation standards, and technical documentation to ensure consistency and compliance. Own the Technical Details: Identify and document novel technical solutions and formulation approaches that may be eligible for intellectual property protection and ensure Clorox's competitive advantage. Support Commercialization: Develop and apply SOPs, test methods, and best practices while leading product and consumer testing, and continuously research ways to evolve and improve R&D tools and approaches to ensure consumer delight and successful product launches. Collaborate Across Functions Work closely with Marketing, Sales, Digital Data, Insights, and cross-functional R&D teams to analyze problems from multiple points of view and connect disparate ideas to create innovative solutions, proposals, and concepts. Grow your Career: Be part of a team that values playing to win, technical curiosity, and raising the bar where your contributions help shape the future of Product Innovation at Clorox. What we look for: Ph.D. Chemistry, Chemical Engineering, or a related field Candidates must have education and expertise in at least one of the following areas: Aqueous oxidants, kinetics, and equilibria for cleaning, bleaching and antimicrobials Organic chemistry, aqueous surfactants, colloids, and interfacial science for household product formulation. Water soluble polymers for household product formulation. Experience in evaluation, characterization, and measurement of technology in their area of expertise Confident self-starter, critical thinker, capable of working independently and cross-functionally with minimal supervision and direction in a fast-paced environment. Workplace type: Our values-based culture connects to our purpose and empowers people to be their best, professionally and personally. We serve a diverse consumer base which is why we believe teams that reflect our consumers bring fresh perspectives, drive innovation, and help us stay attuned to the world around us. That's why we foster an inclusive culture where every person can feel respected, valued, and fully able to participate, and ultimately able to thrive. Learn more. [U.S.]Additional Information: At Clorox, we champion people to be well and thrive, starting with our own people. To help make this possible, we offer comprehensive, competitive benefits that prioritize all aspects of wellbeing and provide flexibility for our teammates' unique needs. This includes robust health plans, a market-leading 401(k) program with a company match, flexible time off benefits (including half-day summer Fridays depending on location), inclusive fertility/adoption benefits, and more. We are committed to fair and equitable pay and are transparent with current and future teammates about our full salary ranges. We use broad salary ranges that reflect the competitive market for similar jobs, provide sufficient opportunity for growth as you gain experience and expand responsibilities, while also allowing for differentiation based on performance. Based on the breadth of our ranges, most new hires will start at Clorox in the first half of the applicable range. Your starting pay will depend on job-related factors, including relevant skills, knowledge, experience and location. The applicable salary range for every role in the U.S. is based on your work location and is aligned to one of three zones according to the cost of labor in your area. -Zone A: $88,700 - $165,900 -Zone B: $81,300 - $152,100 -Zone C: $73,900 - $138,300 All ranges are subject to change in the future. Your recruiter can share more about the specific salary range for your location during the hiring process. This job is also eligible for participation in Clorox's incentive plans, subject to the terms of the applicable plan documents and policies. Please apply directly to our job postings and do not submit your resume to any person via text message. Clorox does not conduct text-based interviews and encourages you to be cautious of anyone posing as a Clorox recruiter via unsolicited texts during these uncertain times. To all recruitment agencies: Clorox (and its brand families) does not accept agency resumes. Please do not forward resumes to Clorox employees, including any members of our leadership team. Clorox is not responsible for any fees related to unsolicited resumes.
    $88.7k-165.9k yearly Auto-Apply 3d ago
  • Scientist/Senior Research Associate

    Caredx 4.5company rating

    Principal research scientist job in Brisbane, CA

    CareDx, Inc., based in Brisbane, California, is a molecular diagnostics company focused on the discovery, development and commercialization of clinically differentiated, high-value, non-invasive diagnostic surveillance solutions for transplant recipients. The Company has commercialized AlloMap , a gene expression test that aids clinicians in identifying heart transplant recipients with stable graft function who have a low probability of moderate/severe acute cellular rejection. CareDx is also pursuing the development of additional products for post-transplant monitoring of other solid organs that use a variety of technologies, including next-generation sequencing, to detect donor-derived cell-free DNA to monitor the health of organs after transplantation. For more information, please visit: *************** Job Description Specifications Title: Scientist or Senior Research Associate Manager: Associate Director, R&D FLSA: Exempt Classification: Regular full Time Department: Research & Development Location: Brisbane (HQ) Management: n/a General Description We are seeking a highly motivated, critical, and creative Scientist or Senior Research Associate to join the CareDx R&D group. This is an exciting opportunity to be part of a growing, dynamic, and collaborative R&D team innovating cutting-edge technology. The new team member will participate in CareDx research activities with the goal of developing novel cell-free DNA-based tests that address critical clinical unmet needs for transplant patients. Responsibilities as follows, but not necessarily limited to: • Lead cell-free DNA projects to create and develop novel nucleic acid analysis technologies and diagnostic tests for transplant recipients • Plan and efficiently execute complex laboratory experiments with excellent attention to detail • Analyze data in close collaboration with biostatistics and bioinformatics teams • Contribute insight toward experimental design and interpretation as well as troubleshoot laboratory processes and protocols • Keep a detailed laboratory notebook and summarize work in research reports and manuscripts • Interface with staff in multiple departments and clearly communicate results with colleagues and R&D management • Support lab efforts to develop technologies, reagents, and controls necessary for the next generation of CareDx services Work Environment: An employee in this position may work in an environment, or visits facilities, in which safety, environmental and health concerns may demand constant attention. Adherence to the Corporate and/or Plant policies, rules, and regulations in these areas is required. Travel: Travel is not a primary aspect of this position although travel may be requested from time to time. Physical Demands: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to use hands and fingers, handle or feel, and talk or hear. The employee frequently is required to sit, stand and walk. There will be periods of time during the workday where you will be sitting for 3-4 hours in a row. Regular use of hands to operate office equipment and type on the keyboard will be required. The employee may occasionally lift and/or move up to 25 pounds. Specific vision abilities required by this job include close vision, and ability to adjust focus. CareDx is an Equal Opportunity Employer. Qualifications • Ph.D. in molecular biology or a related discipline or M.S. with more than 4 years of relevant experience • Strong background in nucleic acid biochemistry and PCR (qPCR, multiplex PCR, and/or digital PCR) • Experience with library preparation for next generation sequencing and evaluation of results • Ability to quickly learn new technologies and incorporate them into your research • Strong grasp of quantitative analysis with a fundamental understanding of statistics • Excellent record keeping and the ability to efficiently work with large data sets • Interest in being part of a vibrant team setting • Industry experience in biotechnology, diagnostics, or life sciences strongly preferred Additional Information Benefits & Perks: We provide Medical, Dental, Vision and Life Insurance, Flexible Spending and Dependent Care Accounts, Commuter Accounts, 401(k), 3 weeks of vacation, 5 days sick leave, 1 personal floating holiday, 9 paid holidays, gym reimbursement, yoga onsite, ping pong, foosball, BBQ's, social hours, and more!
    $99k-157k yearly est. 8h ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Berkeley, CA?

The average principal research scientist in Berkeley, CA earns between $110,000 and $249,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Berkeley, CA

$166,000
Job type you want
Full Time
Part Time
Internship
Temporary