Principal research scientist jobs in Charleston, SC - 20 jobs

The Department of Public Health Sciences at the Medical University of South Carolina invites Master-level Biostatisticians to apply for a position within our group. The DCU specializes in the design, implementation, management, analysis and reporting of multicenter clinical trials, most of which are NIH-funded. This position is for biostatisticians with a Masters degree in biostatistics, applied statistics or related fields, and with professional experience in clinical trials. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001038 COM PHS Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift : The Department of Public Health Sciences at the Medical University of South Carolina invites Master-level Biostatisticians to apply for a position within our group. The DCU specializes in the design, implementation, management, analysis and reporting of multicenter clinical trials, most of which are NIH-funded. This position is for biostatisticians with a Masters degree in biostatistics, applied statistics or related fields, and with professional experience in clinical trials. Job Duties: 1. 35% - Participate in study design development. This will include working with the protocol lead statistician and clinicians on proposals in which analysis plans are described, sample size justifications are proposed, and results are presented in a clear and transparent manner for interpretation by the appropriate audience. This will include development of computer simulation programs to examine the design operating characteristics of the proposed designs. 2. 35% - Report generation for clinical trials. On-going clinical trials require regular reports on data quality, safety and (in some cases) efficacy. The biostatistician will work closely with the study team on centralized risk-based data monitoring and create programs in SAS/R to generate tables and graphics that will assist the study team on evaluating the quality of the incoming data. Reports also will be generated for trial Data Safety and Monitoring Board (DSMB) meetings and at the time the study is finished accrual and data collection is complete. 3. 25% - Analysis of data from clinical studies. This will include the interim and or final data analysis of datasets of varying sizes that result from the clinical trials coordinated by the DCU. Derived datasets will be created by the biostatistician, validation of analyses and programs will be conducted and reports that includes tables and figures, descriptions of methods used and interpretations of results will be included. 4. 5% - Creation of public use datasets. As majority of the trials conducted by the DCU are NIH-funded, there is a requirement that the data be submitted to NIH for public use. The biostatistician will create the public use dataset according to the DCU standard procedures and will work with the investigators to ensure timely and accurate datasets are submitted. MUSC Minimum Requirements: A master's degree in statistics, biostatics or related field. Preferred Experience & Additional Skills: Advanced level of experience in SAS macro language, Proc IML, R or similar application and experience using SAS or other statistical software to conduct simulation studies to assess the operating characteristics (sample size/power) of various clinical trial study designs is desired. A Master of Science (MS or ScM) degree in biostatistics or statistics is required. Candidates should be able to work independently, have experience and ability in data analysis and statistical programming, and excellent oral and written communication skills. At least 1 year of professional programming experience in SAS (preferred), R, and/or Winbugs is required (evidence of experience based on classwork or certifications can be substituted for professional experience). Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

Force Renewal Programs are designed to attract students & recent graduates with management/leadership potential to careers as Federal employees with the Air Force Civilian Service. This is accomplished by recruiting & selecting high-caliber candidates & training them to become competent, effective, & productive employees in a variety of career fields; providing training & developmental opportunities, & preparing them to successfully complete required training & developmental assignments. Summary Force Renewal Programs are designed to attract students & recent graduates with management/leadership potential to careers as Federal employees with the Air Force Civilian Service. This is accomplished by recruiting & selecting high-caliber candidates & training them to become competent, effective, & productive employees in a variety of career fields; providing training & developmental opportunities, & preparing them to successfully complete required training & developmental assignments. Overview Help Accepting applications Open & closing dates 09/29/2025 to 09/28/2026 Salary $49,960 to - $99,314 per year Pay scale & grade GS 7 - 9 Locations FEW vacancies in the following locations: Clear AFB, AK Eielson AFB, AK Elmendorf AFB, AK Little Rock AFB, AR Show morefewer locations (54) Davis Monthan AFB, AZ Luke AFB, AZ Beale AFB, CA Edwards AFB, CA Los Angeles, CA March AFB, CA Travis AFB, CA Vandenberg AFB, CA Buckley AFB, CO Colorado Springs, CO Peterson AFB, CO Dover AFB, DE Eglin AFB, FL Hurlburt Field, FL MacDill AFB, FL Patrick AFB, FL Robins AFB, GA Pearl Harbor, HI Mountain Home AFB, ID Scott AFB, IL Barksdale AFB, LA Hanscom AFB, MA Andrews AFB, MD Whiteman AFB, MO Columbus AFB, MS Keesler AFB, MS Malmstrom AFB, MT Grand Forks AFB, ND Minot AFB, ND Offutt AFB, NE McGuire AFB, NJ Cannon AFB, NM Holloman AFB, NM Kirtland AFB, NM Rome, NY Heath, OH Wright-Patterson AFB, OH Altus AFB, OK Tinker AFB, OK Vance AFB, OK Charleston AFB, SC Ellsworth AFB, SD Arnold AFB, TN Dyess AFB, TX Goodfellow AFB, TX Laughlin AFB, TX San Antonio, TX Hill AFB, UT Dahlgren, VA Langley AFB, VA Pentagon, Arlington, VA Fairchild AFB, WA McChord AFB, WA Warren AFB, WY Remote job No Telework eligible No Travel Required Occasional travel - You may be expected to travel for this position. Relocation expenses reimbursed No Appointment type Internships Work schedule Full-time Service Competitive Promotion potential 12 Job family (Series) * 0401 General Natural Resources Management And Biological Sciences Supervisory status No Security clearance Top Secret Drug test Yes Position sensitivity and risk Special-Sensitive (SS)/High Risk Trust determination process * Suitability/Fitness Financial disclosure No Bargaining unit status No Announcement number K-26-DHA-12807107-MDL Control number 846774300 This job is open to Help The public U.S. Citizens, Nationals or those who owe allegiance to the U.S. Students Current students enrolled in an accredited high school, college or graduate institution. Recent graduates Individuals who have graduated from an accredited educational institute or certificate program within the last 2 years or 6 years for Veterans. Clarification from the agency This public notice is to gather applications that may or may not result in a referral or selection. Duties Help * This is a formal AF intern position in the Recent Palace Acquire Program (PAQ) and, as such, it is centrally funded by HQ AFPC/DPZS. GS-07 * Uses prescribed methods to perform specific, and limited work assignments that are normally minor phases of a broader assignment of a higher-grade professional. * Assists in coordinating projects with engineers, biological scientists, physical scientists, and community planners. * Complies with health, safety, and environmental rules and procedures and performs work in a manner that enhances the safety of the work environment. GS-09 * Participates in providing environmental biological science support in assigned environmental projects through application of professional knowledge and skill in the biological sciences with emphasis on environmental practices, processes, and techniques. * Responsible for executing assigned routine projects, in-house and by contract, to comply with all applicable Federal, state, and local environmental laws and policies. * Assists in the development of curricula and training for assigned program areas. * Complies with health, safety, and environmental rules and procedures and performs work that enhances the safety of the work environment. Requirements Help Conditions of employment * This public notice is to gather applications that may or may not result in a referral or selection * Please read this Public Notice in its entirety prior to submitting your application for consideration * U.S. Citizenship is required * Males must be registered for Selective Service, see *********** * Total salary varies depending on location of position * PCS expenses if authorized will be paid IAW JTR and Air Force Regulations * Recruitment incentives may be authorized * This position is subject to provisions of the DoD Priority Placement Program * Some position may be subject to drug testing * Employee must maintain current certifications * Disclosure of Political Appointments * You will be required to serve a one year probationary period * Some position under this announcement may require either a secret, top secret, or special sensitive clearance Qualifications * The CSA PAQ program requires a degree with overall GPA standing of 2.95 /3.0 or higher. All qualifications must be met prior to August 2026. This must be from an accredited college or university: BASIC REQUIREMENTS for GS-7 and GS-9: Degree: biological sciences, agriculture, natural resource management, chemistry, or related disciplines appropriate to the position. You may qualify if you meet one of the following: 1. GS-7: You must have completed or will complete a 4-year course of study leading to a bachelor's from an accredited institution AND must have documented Superior Academic Achievement (SAA) at the undergraduate level in the following: a) Grade Point Average 2.95 or higher out of a possible 4.0 as recorded on your official transcript or as computed based on 4 years of education or as computed based on courses completed during the final 2 years of curriculum; OR 3.45 or higher out of a possible 4.0 based on the average of the required courses completed in your major field or the required courses in your major field completed during the final 2 years of your curriculum. 2. GS-9: You must have completed 2 years of progressively higher-level graduate education leading to a master's degree or equivalent graduate degree: a) Grade Point Average - 2.95 or higher out of a possible 4.0 as recorded on your official transcript or as computed based on 4 years of education or as computed based on courses completed during the final 2 years of curriculum; OR 3.45 or higher out of a possible 4.0 based on the average of the required courses completed in your major field or the required courses in your major field completed during the final 2 years of your curriculum. If more than 10 percent of total undergraduate credit hours are non-graded, i.e. pass/fail, CLEP, CCAF, DANTES, military credit, etc. you cannot qualify based on GPA. KNOWLEDGE, SKILLS AND ABILITIES (KSAs): Your qualifications will be evaluated on the basis of your level of knowledge, skills, abilities and/or competencies in the following areas: 1. Professional knowledge of the biological sciences (environmental) concepts and principles and standard practices, methods, and techniques to perform, following specific instructions, routine projects or minor phases of a larger and more complex project. 2. Knowledge to study environmental problems requiring investigation of unsanitary or questionable conditions in assigned projects (See Environmental Program Checklist). 3. Basic knowledge of applicable Federal, State, and local laws, regulations, and other guidance to make recommendations concerning assigned restoration, compliance, conservation, pollution prevention, and/or integration principles and practices. 4. Ability to search technical reports, manufacturers' catalogs, and other guidelines to obtain information. 5. Ability to work cooperatively as a team member in the design of environmental systems. 6. Ability to communicate effectively, both orally and in writing, clearly, concisely, and with technical accuracy. PART-TIME OR UNPAID EXPERIENCE: Credit will be given for appropriate unpaid and or part-time work. You must clearly identify the duties and responsibilities in each position held and the total number of hours per week. VOLUNTEER WORK EXPERIENCE: Refers to paid and unpaid experience, including volunteer work done through National Service Programs (i.e., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community; student and social). Volunteer work helps build critical competencies, knowledge and skills that can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience. Education This position has an education requirement. You MUST provide transcripts to support your educational claims. Education must be accredited by an accrediting institution recognized by the U.S. Department of Education. ************************************************** Please submit copies of all Transcripts to include Transferred hours - Official copies are not required at time of application. If selected, you will be required to provide official copies of all Transcripts. *NOTE*Degree Audits are not accepted. If you qualify based on undergraduate education and you have not graduated prior to applying to this position. You may be offered a position contingent upon your final grade point average or class ranking. IF USING EDUCATION TO QUALIFY: You MUST provide transcripts to support your educational claims. Education must be accredited by an accrediting institution recognized by the U.S. Department of Education. FOREIGN EDUCATION: Education completed in foreign colleges or universities may be used to meet the requirements. You must show proof the education credentials have been deemed to be at least equivalent to that gained in conventional U.S. education program. It is your responsibility to provide such evidence when applying. Additional information For DHA Positions: These positions are being filled under Direct-Hire Authority for the Department of Defense for Post-Secondary Students and Recent Graduates. The Secretary of the Air Force has delegated authority by the Office of the Secretary of Defense to directly appoint qualified post-secondary students and recent graduates directly into competitive service positions; these positions may be professional or administrative occupations and are located Air Force-Wide. Positions may be filled as permanent or term with a full-time or part-time work schedule. Pay will vary by geographic location. * The term "Current post-secondary student" means a person who is currently enrolled in, and in good academic standing at a full-time program at an institution of higher education; and is making satisfactory progress toward receipt of a baccalaureate or graduate degree; and has completed at least one year of the program. * The term "recent graduate" means a person who was awarded a degree by an institution of higher education not more than two years before the date of the appointment of such person, except in the case of a person who has completed a period of obligated service in a uniform service of more than four years. Selective Service: Males born after 12-31-59 must be registered or exempt from Selective Service. For additional information, click here. Direct Deposit: All federal employees are required to have direct deposit. Disabled veteran leave is available to a Federal employee hired on/after 5 Nov 2016, who is a veteran with a service-connected disability rating of 30% or more. For more information, click here. If you have questions regarding this announcement and have hearing or speech difficulties click here. Tax Law Impact for PCS: On 22-Dec-2017, Public Law 115-97 - the "Tax Cuts and Jobs Act of 2017" suspended qualified moving expense deductions along with the exclusion for employer reimbursements and payments of moving expenses effective 01-Jan-2018 for tax years 2018 through 2025. When you perform a Civilian Permanent Change of Station (PCS) with the government, the Internal Revenue Service (IRS) considers the majority of your entitlements to be taxable. Visit GSA Bulletin FTR 20-04 here for additional information. Expand Hide additional information Candidates should be committed to improving the efficiency of the Federal government, passionate about the ideals of our American republic, and committed to upholding the rule of law and the United States Constitution. Benefits Help A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new window Learn more about federal benefits. Review our benefits Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered. How you will be evaluated You will be evaluated for this job based on how well you meet the qualifications above. For DHA Positions: These positions are being filled under Direct-Hire Authority for the DoD for Post-Secondary Students and Recent Graduates. The Secretary of the Air Force has delegated authority by the Office of the Secretary of Defense to directly appoint qualified students and recent graduates directly into competitive service positions; positions may be professional or administrative occupations and located Air Force-Wide. Positions may be filled as permanent/term with a full-time/part-time work schedule. Pay will vary by geographic location. * The term "Current post-secondary student" means a person who is currently enrolled and in good academic standing at a full-time program at an institution of higher education; and is progressing toward a baccalaureate or graduate degree; and has completed at least 1 year of the program. * The term "recent graduate" means a person awarded a degree by an institution of higher education not more than 2 years before the date of the appointment of such person, except in the case of a person who has completed a period of obligated service in a uniform service of more than 4 years. Your latest resume will be used to determine your qualifications. Your application package (resume, supporting documents, and responses to the questionnaire) will be used to determine your eligibility, qualifications, and quality ranking for this position. Please follow all instructions carefully. Errors or omissions may affect your rating or consideration for employment. Your responses to the questionnaire may be compared to the documents you submit. The documents you submit must support your responses to the online questionnaire. If your application contradicts or does not support your questionnaire responses, you will receive a rating of "not qualified" or "insufficient information" and you will not receive further consideration for this job. Applicants who disqualify themselves will not be evaluated further. Benefits Help A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new window Learn more about federal benefits. Review our benefits Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered. Required documents Required Documents Help The following documents are required and must be provided with your application for this Public Notice. Applicants who do not submit required documentation to determine eligibility and qualifications will be eliminated from consideration. Other documents may be required based on the eligibility/eligibilities you are claiming. Click here to view the AF Civilian Employment Eligibility Guide and the required documents you must submit to substantiate the eligibilities you are claiming. * Online Application - Questionnaire * Resume - Your resume may NOT exceed two pages, and the font size should not be smaller than 10 pts. You will not be considered for this vacancy if your resume is illegible/unreadable. Additional information on resume requirements can be located under "

A postdoctoral research opportunity is available with Clemson University to conduct research on abiotic and biotic stresses affecting cucurbit crops. The selected applicant will conduct research primarily on biotic factors (e.g., viral and fungal diseases) on cucurbit crops including squashes, cucumber and watermelon. Research assignment will include phenotyping cucurbit and watermelon germplasm for tolerance to biotic factors, selecting appropriate genotypes or single plants with resistance and advancing them to develop homozygous lines, identifying QTL regions and developing molecular markers, determining genes being up or down regulated during host-pathogen interactions. Other research projects can include research on diseases of cucurbits including studies to understand inheritance of host resistance to biotic and abiotic stress, genetic mapping, marker development, differential gene expression during disease development on susceptible and resistant cucurbit genotypes etc. Cucurbit crops that the laboratory primarily works on include watermelon, cucumber, melon, and various gourds. The appointment is full-time for one year and may be renewed for an additional year contingent upon performance and availability of funding. Salary will be commensurate with experience. Benefits include health insurance. Funds will also be available to travel to one national and one division meeting. Funding is not available for relocation expenses. Required qualifications • Ph.D. degree in Horticulture, Genetics, Plant Breeding, Plant Pathology, Plant Biology, Molecular Biology, or related field. • Knowledge and experience in phenotyping plants for resistance to biotic and / or abiotic stress • Knowledge and experience with Next Generation Sequencing and utilizing data to identify QTL regions and develop molecular markers for use in breeding programs. • Excellent communication and collaboration skills, self-motivated, and a willingness to learn new skills and techniques. • Be able to design experiments, initiate research projects, and participate effectively in team projects. • Demonstrated ability to publish in peer-reviewed journals. Preferred qualifications • Experience performing bioinformatic analysis (GWAS, QTLseq etc.) and/or familiarity with scripting languages (i.e. R, Python, Linux etc.) • Experience in field research will be advantageous but is not required. • Knowledge and experience in molecular biology, plant pathology or breeding is preferred but not required. • Experience in molecular biology and/or next generation sequencing technologies. • Basic knowledge of plant genetics and host-resistance is desirable.

The Department of Public Health Sciences at the Medical University of South Carolina invites Master-level Biostatisticians to apply for a position within our group. The DCU specializes in the design, implementation, management, analysis and reporting of multicenter clinical trials, most of which are NIH-funded. This position is for biostatisticians with a Masters degree in biostatistics, applied statistics or related fields, and with professional experience in clinical trials. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001038 COM PHS Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift : The Department of Public Health Sciences at the Medical University of South Carolina invites Master-level Biostatisticians to apply for a position within our group. The DCU specializes in the design, implementation, management, analysis and reporting of multicenter clinical trials, most of which are NIH-funded. This position is for biostatisticians with a Masters degree in biostatistics, applied statistics or related fields, and with professional experience in clinical trials. Job Duties: 1. 35% - Participate in study design development. This will include working with the protocol lead statistician and clinicians on proposals in which analysis plans are described, sample size justifications are proposed, and results are presented in a clear and transparent manner for interpretation by the appropriate audience. This will include development of computer simulation programs to examine the design operating characteristics of the proposed designs. 2. 35% - Report generation for clinical trials. On-going clinical trials require regular reports on data quality, safety and (in some cases) efficacy. The biostatistician will work closely with the study team on centralized risk-based data monitoring and create programs in SAS/R to generate tables and graphics that will assist the study team on evaluating the quality of the incoming data. Reports also will be generated for trial Data Safety and Monitoring Board (DSMB) meetings and at the time the study is finished accrual and data collection is complete. 3. 25% - Analysis of data from clinical studies. This will include the interim and or final data analysis of datasets of varying sizes that result from the clinical trials coordinated by the DCU. Derived datasets will be created by the biostatistician, validation of analyses and programs will be conducted and reports that includes tables and figures, descriptions of methods used and interpretations of results will be included. 4. 5% - Creation of public use datasets. As majority of the trials conducted by the DCU are NIH-funded, there is a requirement that the data be submitted to NIH for public use. The biostatistician will create the public use dataset according to the DCU standard procedures and will work with the investigators to ensure timely and accurate datasets are submitted. MUSC Minimum Requirements: A master's degree in statistics, biostatics or related field. Preferred Experience & Additional Skills: Advanced level of experience in SAS macro language, Proc IML, R or similar application and experience using SAS or other statistical software to conduct simulation studies to assess the operating characteristics (sample size/power) of various clinical trial study designs is desired. A Master of Science (MS or ScM) degree in biostatistics or statistics is required. Candidates should be able to work independently, have experience and ability in data analysis and statistical programming, and excellent oral and written communication skills. At least 1 year of professional programming experience in SAS (preferred), R, and/or Winbugs is required (evidence of experience based on classwork or certifications can be substituted for professional experience). Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Division of Hematology/Oncology at the Medical University of South Carolina is seeking a highly motivated Senior Research Associate to join the laboratory of Dr. Russell W. Jenkins. This position will support and manage day-to-day lab operations and play a key role in planning and executing research projects focused on understanding and overcoming resistance to cancer immunotherapy. Research efforts will involve in vivo, ex vivo, and in vitro tumor model systems, with a particular emphasis on murine tumor models. The ideal candidate will have extensive experience in working with mouse models of cancer, and a strong background in cancer cell biology, T cell biology, immunology, and cancer immunotherapy. This position requires a high level of technical and scientific expertise, particularly in the use of in vivo tumor models to explore therapeutic mechanisms and responses. In addition to managing lab operations and conducting experiments, the candidate will contribute to the development of new research directions, perform independent data analysis, support manuscript and grant preparation, and present findings at scientific meetings. This role also involves processing patient samples from the clinic using advanced lab technologies to evaluate patient response and resistance to immunotherapy. The research is part of a broader collaborative effort between MUSC and the Hollings Cancer Center focused on advancing cancer immunotherapy. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC000970 COM DOM Hematology/Oncology CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Job Duties: 30% - In Vivo Mouse Tumor Model Development and Management: Design, execute, and analyze experiments utilizing mouse models to study cancer progression and treatment responses, including tumor implantation, monitoring, and endpoint analysis for efficacy (tumor volume, survival) and correlative (immunophenotyping, single cell RNA-sequencing) studies using established and novel mouse models of cancer Develop and validate new mouse cancer models to investigate specific tumor types and therapeutic strategies, specifically transgenic models, including inducible and conditional knockout modes, and knock-in models Supervise mouse colonies, ensuring compliance with ethical standards and institutional animal care regulations. 20% - Lab Management: In conjunction with the PI provide management of laboratory staff, including training, scheduling (lab meetings), and performance evaluations. Oversee day-to-day laboratory operations, including maintenance of equipment, inventory management, and ordering supplies. Ensure compliance with safety protocols and regulatory requirements in the laboratory. Monitor and maintain laboratory budgets and expenditures. Facilitate communication between laboratory personnel and administrative staff. Collaborate with principal investigators and research teams to facilitate project execution and data collection. Assist in the development and implementation of research protocols and standard operating procedures (SOPs). Participate in grant writing and provide administrative support for research projects. 20% - Ex Vivo and In Vitro Tumor Model Development and Management: Ex vivo 3D microfluidic culture, drug/antibody treatment of murine- and patient-derived organotypic tumor spheroids (MDOTS/PDOTS) and cell line derived monotypic tumor spheroids (MTS) Developing augmented 3D microfluidic organotypic tumor spheroid cultures using matched (autologous) peripheral blood mononuclear cells (PBMCs) or CD3+ enriched peripheral T lymphocytes co-culture with MTS/PDOTS Perform requisite fluorescence-based viability assessment of MDOTS, PDOTS, and MTS, including staining, microscope operation, image acquisition and image analysis Maintain internal records related to MDOTS, PDOTS, and MTS processing along with associated meta-data Collaborate with multidisciplinary teams, including molecular biologists, biochemists, and clinical researchers, to support translational research efforts. 10% - Lab Maintenance: Troubleshoots and resolves equipment malfunctions to minimize downtime and ensure smooth operation of laboratory instruments and workflows. Identifies and resolves issues in experimental assays to ensure accurate and reliable results, maintaining the integrity of laboratory procedures and data quality. 10% - Research and Therapeutic Development: Develops new research directions focused on novel small molecule, large molecule, and cellular therapeutics. Designs and implements strategies for the evaluation of emerging therapeutics approaches. Develops and adapts experimental models and methodologies to support innovative research initiatives. Collaborates with cross-functional teams to advance scientific discovery and therapeutic innovation. 5% - Data analysis and manuscript preparation: Graphing and visualization of data with software including Graphpad Prism, FlowJo, Snapgene, Biorender, Microsoft Powerpoint, Microsoft Excel, and Adobe Illustrator Document and present research findings in internal meetings, conferences, and peer-reviewed publications. Preparing publication quality figures Participate in grant writing and provide administrative support for research projects. 5% - Lab Member Training and Supervision: Assist in mentoring junior scientists and students in laboratory techniques and research methodologies. Minimum Experience and Training Requirements: A PhD with 5 years post-doctorate experience and one year experience as a staff scientist. Preferred Experience, Knowledge, and Abilities: Previous experience working with patient-tumor tissue is ideal, but not essential. Previous laboratory management experience and supervising research technicians required. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

We are seeking a highly motivated scientist interested in brain tumor immunology, a 1-year position at the Medical University of South Carolina. The scientist would be responsible in handling and processing of human brain tumor specimens including cryopreservation and tissue dissociation, extraction of nucleic acids, flow cytometry, microscopy imaging, single-cell RNA sequencing, and data analysis. The scientist would also be expected to assist with animal cancer model experiments including genetic tumor models, implantation of tumor cells, and eventually administration of therapies. A background in molecular and cell biology, immunology, or neuroscience is desirable; however, otherwise motivated candidates interested in brain tumor research will be considered. Interest in clinical outcomes research of brain tumors is a strong plus. A staff scientist position at the Hollings Cancer Center (NCI-designated cancer center) of the Medical University of South Carolina is available in the newly forming Strickland Laboratory. Our primary aim is to understand the role of tumor heterogeneity and the tumor immune microenvironment as it permits immune tolerance in brain tumors. Our goal is to translate basic cancer immunology into targeted clinical immunotherapies. We are particularly interested in glioblastoma and aggressive subtypes of meningioma. We focus on the interplay of immune cell proportions and communications within the tumor immune microenvironment as it correlates with tumor progression. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC000986 COM NSGY General CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Job Duties: 30%: Assist with experimental data collections involving brain tumor human tissue processing. Collects samples (FFPE and in vivo), performs sample analyses, and extracts measurement data from experiments. 30%: Assist with study design and maintenance of study organization, including data entry and data storage through both document hard copies and electronically and to adapt new procedures, methods, or instrumentation relative to research procedures. This job duty includes organizing, writing, and renewing human (IRB) protocols, ensuring compliance with regulations, and maintaining communication with the institutional IRB. 15%: Oversee media preparation and equipment maintenance; quality control analysis reagents 10%: Supervise other personnel in the laboratory to coordinate research efforts for increased efficiency; participate in training of other lab members as needed 10%: Assist with ordering and procurement of supplies and equipment and with general maintenance of laboratory 5%: Other duties as assigned MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience. Additional Knowledge, Skills, and Abilities Preferred: * Proficiency with immunology and/or tumor genetics investigations * Familiarity with single cell RNA sequencing workflow and data processing * Familiarity with immunohistochemistry and immunofluorescence * Weekend, holiday, and evening work as required for experiments. Degree of Supervision: This position will work under direct supervision of the Strickland Brain Tumor Immunology PI, which will require numerous meetings on weekly and ad hoc bases. The staff scientist will primarily work in MUSC's Hollings Cancer Center, with an expectation to attend meetings and other project-related activities as necessary. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Dahne Lab within the Department of Psychiatry and Behavioral Sciences and the Hollings Cancer Center at the Medical University of South Carolina announce a staff scientist I position in behavioral health (smoking cessation, mood disorders) and technology-based interventions (telehealth, remote clinical trials). The staff scientist will assist with ongoing clinical trials related to smoking cessation and depression treatment. Additional ongoing projects center around development of innovative methods to improve the feasibility and rigor of remote trials. These projects are funded via multiple NIH grants including R01s and Small Business Technology Transfer (STTR) awards. Opportunities exist to develop new research projects within ongoing studies and for secondary analyses of existing datasets. Interest in academic entrepreneurship is welcomed, though not required. The candidate will have opportunities to collaborate on and lead scientific articles, collaborate on and lead new NIH grant applications, and receive mentoring in developing new areas of grant-funded research relevant to behavioral health and telehealth. Applications from candidates that can extend our research in new and exciting directions (e.g., oncology, comorbid mental health and substance use disorders, novel technologies, informatics) would be particularly welcomed, and possibilities exist for pilot projects to advance future funding potential. The successful candidate will be self-motivated, goal-oriented, and working toward research independence. A PhD, MD, or equivalent with two years post-doctorate experience is required. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001039 COM PSYCH Addiction Science CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift FLSA: Salaried Work Schedule: M-F, 8:30 am - 5:00 pm Job Duties: (20%) - The staff scientist will manage various projects of moderate size with collaborative input from the PI. This will include NIH-funded clinical trials of novel telehealth and digital health interventions to improve behavioral health. Project management will include overseeing recruitment milestones, preparing study reports, contributing to statistical analyses, and other related duties. (20%) - The staff scientist will contribute intellectually to project development and design for new grant ideas. This will include compiling literature reviews, developing statistical analysis plans, writing grant sections with PI oversight, and other related duties. (15%) - Creates and implements effective approaches for accomplishing PI's research objectives (15%) - Develops, submits, and collaborates on competitive applications for intra and extramural grant funding (15%) - Publishes scholarly works (10%) - Identifies and troubleshoots problems that impact research conduct with the PI (5%) - Gives presentations at society meetings MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience. Preferred Training and Experience: Record of research productivity and excellence in scientific writing, statistical proficiency Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Jiang Lab at the Medical University of South Carolina aims to understand the role of microbiome, inflammation, pathogenic autoantibody, and B cell dysfunction in human disease immunopathogenesis (ie., HIV, drug abuse). The part-time technician, postdoc, or staff scientist will conduct HIV and drug abuse projects in the lab, train the lab members, and help run the lab. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001032 COM PHARM Administration CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 20 Work Shift Job Title: Part-time staff scientist Full Time or Part Time: Part-time MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience plus evidence of scholarly activity as demonstrated by at least five first author publications. Additional Knowledge, skill, ability preferred: * The ideal candidate is to have the experience of doing experiments related to immunology or molecular biology. * Detailed-driven. Guideline and Supervision: * Detailed-driven. Job Duties: 1. Maintain lab routine work, and apply for lab safety documents (20%) * Routine lab maintenance (i.e., autoclave, tip preparation, liquid nitrogen tank refilling). * Support for lab safety applications. 2. Conduct immunologic and molecular biologic experiments in human studies and collect and analyze data (30%) * Assays such as qPCR, flow cytometry, ELISA. * Report research results to PI every week. 3. Conduct biologic experiments (i.e., western, IF, qPCR) in animal studies and collect and analyze data (30%) * Assays such as western, IF, qPCR, mouse strain breeding, genotyping, and maintenance. * Report research results to PI every week 4. Refine and standardize existing experimental procedures and train new lab members. (20%) * Maintain protocol and apply for IBC/IACUC * Train new lab members Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

We are seeking a highly motivated scientist interested in brain tumor immunology, a 1-year position at the Medical University of South Carolina. The scientist would be responsible in handling and processing of human brain tumor specimens including cryopreservation and tissue dissociation, extraction of nucleic acids, flow cytometry, microscopy imaging, single-cell RNA sequencing, and data analysis. The scientist would also be expected to assist with animal cancer model experiments including genetic tumor models, implantation of tumor cells, and eventually administration of therapies. A background in molecular and cell biology, immunology, or neuroscience is desirable; however, otherwise motivated candidates interested in brain tumor research will be considered. Interest in clinical outcomes research of brain tumors is a strong plus. A staff scientist position at the Hollings Cancer Center (NCI-designated cancer center) of the Medical University of South Carolina is available in the newly forming Strickland Laboratory. Our primary aim is to understand the role of tumor heterogeneity and the tumor immune microenvironment as it permits immune tolerance in brain tumors. Our goal is to translate basic cancer immunology into targeted clinical immunotherapies. We are particularly interested in glioblastoma and aggressive subtypes of meningioma. We focus on the interplay of immune cell proportions and communications within the tumor immune microenvironment as it correlates with tumor progression. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC000986 COM NSGY General CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Job Duties: 30%: Assist with experimental data collections involving brain tumor human tissue processing. Collects samples (FFPE and in vivo), performs sample analyses, and extracts measurement data from experiments. 30%: Assist with study design and maintenance of study organization, including data entry and data storage through both document hard copies and electronically and to adapt new procedures, methods, or instrumentation relative to research procedures. This job duty includes organizing, writing, and renewing human (IRB) protocols, ensuring compliance with regulations, and maintaining communication with the institutional IRB. 15%: Oversee media preparation and equipment maintenance; quality control analysis reagents 10%: Supervise other personnel in the laboratory to coordinate research efforts for increased efficiency; participate in training of other lab members as needed 10%: Assist with ordering and procurement of supplies and equipment and with general maintenance of laboratory 5%: Other duties as assigned MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience. Additional Knowledge, Skills, and Abilities Preferred: · Proficiency with immunology and/or tumor genetics investigations · Familiarity with single cell RNA sequencing workflow and data processing · Familiarity with immunohistochemistry and immunofluorescence · Weekend, holiday, and evening work as required for experiments. Degree of Supervision: This position will work under direct supervision of the Strickland Brain Tumor Immunology PI, which will require numerous meetings on weekly and ad hoc bases. The staff scientist will primarily work in MUSC's Hollings Cancer Center, with an expectation to attend meetings and other project-related activities as necessary. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The laboratory of Dr. Dan Sprague has an opening for a collegial, motivated, and productive organic chemist to complement our growing laboratory and fill the role of Staff Scientist I starting after March 1, 2026. MUSC has an initiative to develop chemical biology and drug discovery efforts institution-wide, and the person hired into this position is meant to play a leading role in establishing these efforts and supporting faculty throughout MUSC. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC000954 COM BIOCHEM Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift The Staff Scientist will be responsible for leading projects related to the synthesis of chemical tools, probes, and small molecule preclinical candidates to support the needs of faculty across MUSC. The Staff Scientist will manage all aspects of daily chemistry laboratory function and regulatory compliance in conjunction with the PI, and alongside our lab manager. The Staff Scientist will design synthetic routes, carry-out the synthesis of these molecules, and fully characterize new molecules in a timely fashion. The Staff Scientist will be responsible, in conjunction with the PI, for advising and fostering collaborations with MUSC faculty regarding the development of small molecules. The candidate will keep meticulously organized notes and data. The candidate will also (in conjunction with the PI) assist in training new lab members in safety and chemistry techniques as the need arises. There will be ample opportunity for co-authorship on manuscripts and patents, and Dr. Sprague is committed to helping develop the capabilities of the Staff Scientist in molecular pharmacology and cell biology as needs arise or if interested. * Required Skills: The candidate is required to have a minimum of a Ph.D. in Chemistry or related subjects with extensive experience and demonstrated productivity in multi-step syntheses. * Preferred Skills: The preferred candidate will have high-quality publications detailing their efforts in synthesis and demonstrated leadership skills. Postdoctoral experience is a plus but not required, and experience in high-throughput screening, assay development, and/or mammalian cell culture is a benefit, but not required. Guidelines and Supervision: Must be able to work efficiently and independently under the direction of the PI. Must be able to drive projects forward in a timely manner to meet collaborative demands across the institution. Job Duties: * Executes synthetic routes to provide small molecules to support efforts within the Sprague Lab and across the institution (30%) * Fully characterizes small molecules (20%) * Helps execute small molecule screens as needed (10%) * Helps to train junior members of the lab in proper lab safety and techniques in chemistry (10%) * Prepares exceptional, well-organized daily laboratory records of experimental procedures and results (10%) * Participates in drafting manuscripts, grants, and patents as needed (10%) * Presents research routinely to the lab at lab meetings, participates in lab meeting discussions, and leads collaborative efforts across the institution (5%) * Upon request, performs other tasks requested to maintain a smooth operation of the laboratory (5%) Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The laboratory of Dr. Dan Sprague has an opening for a collegial, motivated, and productive organic chemist to complement our growing laboratory and fill the role of Staff Scientist I starting after March 1, 2026. MUSC has an initiative to develop chemical biology and drug discovery efforts institution-wide, and the person hired into this position is meant to play a leading role in establishing these efforts and supporting faculty throughout MUSC. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC000954 COM BIOCHEM Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift The Staff Scientist will be responsible for leading projects related to the synthesis of chemical tools, probes, and small molecule preclinical candidates to support the needs of faculty across MUSC. The Staff Scientist will manage all aspects of daily chemistry laboratory function and regulatory compliance in conjunction with the PI, and alongside our lab manager. The Staff Scientist will design synthetic routes, carry-out the synthesis of these molecules, and fully characterize new molecules in a timely fashion. The Staff Scientist will be responsible, in conjunction with the PI, for advising and fostering collaborations with MUSC faculty regarding the development of small molecules. The candidate will keep meticulously organized notes and data. The candidate will also (in conjunction with the PI) assist in training new lab members in safety and chemistry techniques as the need arises. There will be ample opportunity for co-authorship on manuscripts and patents, and Dr. Sprague is committed to helping develop the capabilities of the Staff Scientist in molecular pharmacology and cell biology as needs arise or if interested. Required Skills: The candidate is required to have a minimum of a Ph.D. in Chemistry or related subjects with extensive experience and demonstrated productivity in multi-step syntheses. Preferred Skills: The preferred candidate will have high-quality publications detailing their efforts in synthesis and demonstrated leadership skills. Postdoctoral experience is a plus but not required, and experience in high-throughput screening, assay development, and/or mammalian cell culture is a benefit, but not required. Guidelines and Supervision: Must be able to work efficiently and independently under the direction of the PI. Must be able to drive projects forward in a timely manner to meet collaborative demands across the institution. Job Duties: Executes synthetic routes to provide small molecules to support efforts within the Sprague Lab and across the institution (30%) Fully characterizes small molecules (20%) Helps execute small molecule screens as needed (10%) Helps to train junior members of the lab in proper lab safety and techniques in chemistry (10%) Prepares exceptional, well-organized daily laboratory records of experimental procedures and results (10%) Participates in drafting manuscripts, grants, and patents as needed (10%) Presents research routinely to the lab at lab meetings, participates in lab meeting discussions, and leads collaborative efforts across the institution (5%) Upon request, performs other tasks requested to maintain a smooth operation of the laboratory (5%) Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Dahne Lab within the Department of Psychiatry and Behavioral Sciences and the Hollings Cancer Center at the Medical University of South Carolina announce a staff scientist I position in behavioral health (smoking cessation, mood disorders) and technology-based interventions (telehealth, remote clinical trials). The staff scientist will assist with ongoing clinical trials related to smoking cessation and depression treatment. Additional ongoing projects center around development of innovative methods to improve the feasibility and rigor of remote trials. These projects are funded via multiple NIH grants including R01s and Small Business Technology Transfer (STTR) awards. Opportunities exist to develop new research projects within ongoing studies and for secondary analyses of existing datasets. Interest in academic entrepreneurship is welcomed, though not required. The candidate will have opportunities to collaborate on and lead scientific articles, collaborate on and lead new NIH grant applications, and receive mentoring in developing new areas of grant-funded research relevant to behavioral health and telehealth. Applications from candidates that can extend our research in new and exciting directions (e.g., oncology, comorbid mental health and substance use disorders, novel technologies, informatics) would be particularly welcomed, and possibilities exist for pilot projects to advance future funding potential. The successful candidate will be self-motivated, goal-oriented, and working toward research independence. A PhD, MD, or equivalent with two years post-doctorate experience is required. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001039 COM PSYCH Addiction Science CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift FLSA: Salaried Work Schedule: M-F, 8:30 am - 5:00 pm Job Duties: * (20%) - The staff scientist will manage various projects of moderate size with collaborative input from the PI. This will include NIH-funded clinical trials of novel telehealth and digital health interventions to improve behavioral health. Project management will include overseeing recruitment milestones, preparing study reports, contributing to statistical analyses, and other related duties. * (20%) - The staff scientist will contribute intellectually to project development and design for new grant ideas. This will include compiling literature reviews, developing statistical analysis plans, writing grant sections with PI oversight, and other related duties. * (15%) - Creates and implements effective approaches for accomplishing PI's research objectives * (15%) - Develops, submits, and collaborates on competitive applications for intra and extramural grant funding * (15%) - Publishes scholarly works * (10%) - Identifies and troubleshoots problems that impact research conduct with the PI * (5%) - Gives presentations at society meetings MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience. Preferred Training and Experience: Record of research productivity and excellence in scientific writing, statistical proficiency Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

Seeking an individual, preferably with microsurgical experience for a position in neuroimmunology for projects that encompasses basic and translational research. Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For this position, work will be focused on mouse models of stroke and traumatic brain injury the. Ideally, the candidate will have experience with the murine middle cerebral artery occlusion model, although training can be provided. Other aspects of the project will include high resolution and confocal microscopy, cellular and molecular immune profile analysis, therapeutic evaluation of drugs, and detailed assessments of motor and cognitive functions. The laboratory is also developing novel transgenic animals for mechanistic studies, and is involved in the development (and commercialization) of novel therapeutic approaches. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001032 COM PHARM Administration CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Duties/Responsibilities Participate in a project related to above described work, including perform surgical procedures. Prepare sections from mouse brains and process for histology and immune-microscopy. Perform various microscopy techniques. Evaluate mice via various behavioral tasks. 35% In terms of the above listed areas of research, perform high dimensional analyses of post-injury immune landscape, analyze and interpret data. Will also involve use of image analysis software and generation of computer images. Determine behavioral outcomes in terms of pathophysiological findings. 35% Collaborate with other lab personnel in related projects. Participate in lab meetings and project-specific meetings with other lab personnel. 15% Keep records and up to date lab notebook/lab archives. Assist with writing manuscripts and grants. Keep up to date with relevant literature. 15% MUSC Minimum Training and Experience: A Ph.D., M.D. or equivalent with two years postdoctorate experience plus evidence of scholarly activity as demonstrated by at least five first author publications. Preferred Minimum Experience and Training Requirements: A PhD degree in biology or other natural, life or health care science related to the assigned area of research. At least 2 years postdoctoral experience. For general information on the University and Research, see: ******************************************** and ************************** For further information or to apply (CV and names of 3 referees), please contact Dr. Stephen Tomlinson: ***************** Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Senior Postdoctoral Researcher will play a key leadership role in advancing ongoing research programs in musculoskeletal biology and tissue regeneration. The ideal candidate will possess strong expertise in bioinformatics, musculoskeletal histology, and molecular biology, combined with demonstrated ability to lead and mentor trainees in a dynamic, multidisciplinary environment. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Research Grant Cost Center CC001138 CDM Orthodontics Pay Rate Type Hourly Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift 20%: Lead and conduct independent and collaborative research projects focused on musculoskeletal tissue development ,regeneration, and disease modeling. 20%: Perform advanced bioinformatics analyses, including transcriptomic, single-cell, and spatial omics data interpretation to support mechanistic discoveries. 20%: Manage daily laboratory operations, including experimental design, data management, and compliance with institutional and safety protocols. 15%: Oversee and execute musculoskeletal histology, immunohistochemistry, and imaging studies to evaluate tissue architecture and cellular dynamics. 10%: Supervise and mentor PhD students, junior postdoctoral fellows, and research staff , fostering an inclusive, productive, and scientifically rigorous environment. 10%: Contribute to manuscript preparation, grant writing, and dissemination of findings at national and international meetings. 5%: Collaborate closely with clinical and engineering teams to integrate multi-scale biological and computational data. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Center of Excellence in Behavioral Health Nursing at MUSC seeks a full-time Postdoctoral Fellow to join a dynamic interdisciplinary team advancing trauma-focused behavioral health research and clinical care. This one-year fellowship (with the possibility of renewal for a second year) provides mentored research training as well as other training that aligns with the candidate's needs and interests (e.g., clinical experience with patient populations). Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Regular Cost Center CC001081 CON Office Of Research Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Qualifications • Ph.D. in Clinical Psychology, Nursing Science, Public Health, or related behavioral/social science. • Demonstrated interest in trauma-focused or behavioral health research. • Experience with quantitative, qualitative, or mixed-methods approaches preferred. About the Center The Center is dedicated to improving access, quality, and innovation in behavioral health care through education, research, and clinical practice. The Center provides infrastructure for mixed-methods research, implementation science, and digital health innovation, with access to pilot funding, mentorship from NIH-funded faculty, and collaboration opportunities across nursing and psychiatry. To learn more about the Center visit: *********************************************************** Responsibilities • Conduct research aligned with the Center's focus on behavioral health. • Contribute to ongoing studies and develop independent research ideas and grant proposals. • Prepare manuscripts, presentations, and conference submissions. • Participate in professional development activities, seminars, and interdisciplinary collaborations. Training & Mentorship Fellows will receive individualized mentorship, protected time for scholarly development, access to large data sets, and support for external training and conference participation. The position provides a pathway toward independence as a clinical scientist and academic leader. Fellowship Benefits • Competitive pay and benefits package. • Access to institutional resources, including research labs, clinical facilities, and professional development programs. • Support for conference travel and professional networking. Full-time | 12-month appointment (August 1, 2026 - July 30, 2027) with the potential for renewal for a second-year contingent upon performance and funding. **Please submit a cover letter, CV, two representative publications, and contact information for three references** Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Center of Excellence in Behavioral Health Nursing at MUSC seeks a full-time Postdoctoral Fellow to join a dynamic interdisciplinary team advancing trauma-focused behavioral health research and clinical care. This one-year fellowship (with the possibility of renewal for a second year) provides mentored research training as well as other training that aligns with the candidate's needs and interests (e.g., clinical experience with patient populations). Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Regular Cost Center CC001081 CON Office Of Research Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Qualifications * Ph.D. in Clinical Psychology, Nursing Science, Public Health, or related behavioral/social science. * Demonstrated interest in trauma-focused or behavioral health research. * Experience with quantitative, qualitative, or mixed-methods approaches preferred. About the Center The Center is dedicated to improving access, quality, and innovation in behavioral health care through education, research, and clinical practice. The Center provides infrastructure for mixed-methods research, implementation science, and digital health innovation, with access to pilot funding, mentorship from NIH-funded faculty, and collaboration opportunities across nursing and psychiatry. To learn more about the Center visit: *********************************************************** Responsibilities * Conduct research aligned with the Center's focus on behavioral health. * Contribute to ongoing studies and develop independent research ideas and grant proposals. * Prepare manuscripts, presentations, and conference submissions. * Participate in professional development activities, seminars, and interdisciplinary collaborations. Training & Mentorship Fellows will receive individualized mentorship, protected time for scholarly development, access to large data sets, and support for external training and conference participation. The position provides a pathway toward independence as a clinical scientist and academic leader. Fellowship Benefits * Competitive pay and benefits package. * Access to institutional resources, including research labs, clinical facilities, and professional development programs. * Support for conference travel and professional networking. Full-time | 12-month appointment (August 1, 2026 - July 30, 2027) with the potential for renewal for a second-year contingent upon performance and funding. Please submit a cover letter, CV, two representative publications, and contact information for three references Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

We are seeking highly motivated individuals for a Postdoctoral Fellow position to study neurovascular function and neuroinflammation in projects that span both basic and translational research. Our recently NIH-funded research focuses on the role of pericytes in neurovascular dysfunction associated with Alzheimer's disease and sepsis. Specifically, we investigate how pericyte-mediated vascular dysfunction contributes to altered blood-brain barrier permeability and cerebral blood flow. A reduction in cerebral blood flow is a significant factor in the development of dementia and Alzheimer's disease. Our work aims to deepen the mechanistic understanding of pericyte function while also identifying clinically relevant therapeutic strategies. We employ a wide range of complementary approaches, including molecular and cellular biology, advanced imaging technologies, and genetically modified mouse models. Our recently acquired twophoton microscope enhances our ability to conduct cutting-edge in vivo imaging. We are actively developing multiple projects to address critical gaps in the neurovascular research field, supported by NIH R35 and R01 funding.The postdoctoral fellow will be supervised by Dr. Hongkuan Fan, Department of Pathology and Laboratory Medicine, who will provide training and mentorship in neurovascular and neuroinflammation research. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Regular Cost Center CC001002 COM PATH Basic Research CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift Summary We are seeking highly motivated individuals for a Postdoctoral Fellow position to study neurovascular function and neuroinflammation in projects that span both basic and translational research. Our recently NIH-funded research focuses on the role of pericytes in neurovascular dysfunction associated with Alzheimer's disease and sepsis. Specifically, we investigate how pericyte-mediated vascular dysfunction contributes to altered blood-brain barrier permeability and cerebral blood flow. A reduction in cerebral blood flow is a significant factor in the development of dementia and Alzheimer's disease. Our work aims to deepen the mechanistic understanding of pericyte function while also identifying clinically relevant therapeutic strategies. We employ a wide range of complementary approaches, including molecular and cellular biology, advanced imaging technologies, and genetically modified mouse models. Our recently acquired twophoton microscope enhances our ability to conduct cutting-edge in vivo imaging. We are actively developing multiple projects to address critical gaps in the neurovascular research field, supported by NIH R35 and R01 funding. The postdoctoral fellow will be supervised by Dr. Hongkuan Fan, Department of Pathology and Laboratory Medicine, who will provide training and mentorship in neurovascular and neuroinflammation research. Qualifications Ph.D. and/or M.D. in neuroscience, immunology, vascular biology, or a related discipline Strong communication and organizational skills Prior experience with small animal surgery and two-photon imaging is highly preferred Job Responsibilities Lead an independent project related to neurovascular function in sepsis or Alzheimer's disease (35%) Perform complex experiments and data analysis; manage animal surgeries and breeding colonies (35%) Operate and maintain lab equipment (e.g., optical, mechanical, and electrical devices); assist with related lab projects as needed (15%) Conduct literature reviews, maintain detailed lab notebooks, and contribute to manuscript preparation (15%) Preferred Experience & Additional Skills Ph.D. in biology, neuroscience, immunology, vascular biology, or a related field Experience with in vivo imaging (two-photon microscopy) and mouse surgical techniques is highly desirable Minimum Requirements Ph.D. or M.D./Ph.D. in a relevant scientific field Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Department of Biochemistry & Molecular Biology at the Medical University of South Carolina (MUSC) invites applications for a Postdoctoral Fellow position in the laboratory of Dr. Huimin Zhang, who joined MUSC in November 2025. The Zhang Lab focuses on DNA damage repair and cancer biology, investigating the molecular mechanisms underlying genomic instability and developing strategies to exploit these mechanisms for cancer therapy. Research emphasizes tumor suppressor genes, oncogenes, and other genes involved in DNA damage response pathways that contribute to tumor initiation, progression, and metastasis. The lab particularly studies how cells respond to chemotherapy and maintain genomic stability, with a focus on topoisomerase-targeting agents (Molecular & Cellular Proteomics, 2025, DOI: 10.1016/j.mcpro.2025.101082; Science Advances, 2023, DOI: 10.1126/sciadv.adi6681; Nature Communications, 2022, DOI: 10.1038/s41467-022-31801-7; Nucleic Acids Research, 2019, DOI: 10.1093/nar/gkz769; Journal of Biological Chemistry, 2016, DOI: 10.1074/jbc.M116.755991). The lab employs a broad range of biochemical, molecular, and cellular approaches, including large-scale proteomics and genome-wide CRISPR/Cas9 screening to explore cancer-related protein-protein, gene-gene, and gene-drug interactions. We seek applicants who are self-motivated, career-oriented, and enthusiastic to join an exciting and highly interactive research team. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Regular Cost Center CC000954 COM BIOCHEM Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift The Postdoctoral Fellow will lead and conduct independent research projects under the supervision of the Principal Investigator (PI), contribute to manuscript preparation and publication, and participate in project management, grant writing, and career development activities. The fellow will collaborate closely with the PI and lab members in all aspects of research. Preferred additional knowledge, skills, and abilities: * Self-motivated and career oriented. * Strong background in biochemistry, molecular biology, and cell biology * Hands-on experience with molecular and cellular biology * Proven ability to design, execute, and analyze experiments independently * Excellent organizational, written, and oral communication skills * Demonstrated publication record in peer-reviewed journals * Ability to work collaboratively within a multidisciplinary research team * Creative thinking, attention to detail, and commitment to scientific rigor Job Duties: Experimental design and execution (35%) * Design and conduct experiments using state-of-the-art biochemical, molecular, and cellular approaches to study DNA repair mechanisms and chemotherapy response. Data analysis and interpretation (35%) * Collect, organize, and analyze experimental data. Maintain detailed laboratory records and ensure data integrity. Interpret findings and plan follow-up experiments. Manuscript and grant preparation (20%) * Prepare figures and text for publications and grant proposals. Contribute to writing manuscripts, abstracts, and reports. Present findings in lab meetings, departmental seminars, and scientific conferences. Laboratory maintenance and compliance (10%) * Assist in maintaining laboratory organization, equipment, and supply inventories. Ensure compliance with institutional safety and regulatory policies. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************

The Department of Biochemistry & Molecular Biology at the Medical University of South Carolina (MUSC) invites applications for a Postdoctoral Fellow position in the laboratory of Dr. Huimin Zhang, who joined MUSC in November 2025. The Zhang Lab focuses on DNA damage repair and cancer biology, investigating the molecular mechanisms underlying genomic instability and developing strategies to exploit these mechanisms for cancer therapy. Research emphasizes tumor suppressor genes, oncogenes, and other genes involved in DNA damage response pathways that contribute to tumor initiation, progression, and metastasis. The lab particularly studies how cells respond to chemotherapy and maintain genomic stability, with a focus on topoisomerase-targeting agents (Molecular & Cellular Proteomics, 2025, DOI: 10.1016/j.mcpro.2025.101082; Science Advances, 2023, DOI: 10.1126/sciadv.adi6681; Nature Communications, 2022, DOI: 10.1038/s41467-022-31801-7; Nucleic Acids Research, 2019, DOI: 10.1093/nar/gkz769; Journal of Biological Chemistry, 2016, DOI: 10.1074/jbc.M116.755991). The lab employs a broad range of biochemical, molecular, and cellular approaches, including large-scale proteomics and genome-wide CRISPR/Cas9 screening to explore cancer-related protein-protein, gene-gene, and gene-drug interactions. We seek applicants who are self-motivated, career-oriented, and enthusiastic to join an exciting and highly interactive research team. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type Regular Cost Center CC000954 COM BIOCHEM Operations CC Pay Rate Type Salary Pay Grade University-00 Pay Range 0.00 - 0.00 - 0.000 Scheduled Weekly Hours 40 Work Shift The Postdoctoral Fellow will lead and conduct independent research projects under the supervision of the Principal Investigator (PI), contribute to manuscript preparation and publication, and participate in project management, grant writing, and career development activities. The fellow will collaborate closely with the PI and lab members in all aspects of research. Preferred additional knowledge, skills, and abilities: Self-motivated and career oriented. Strong background in biochemistry, molecular biology, and cell biology Hands-on experience with molecular and cellular biology Proven ability to design, execute, and analyze experiments independently Excellent organizational, written, and oral communication skills Demonstrated publication record in peer-reviewed journals Ability to work collaboratively within a multidisciplinary research team Creative thinking, attention to detail, and commitment to scientific rigor Job Duties: Experimental design and execution (35%) Design and conduct experiments using state-of-the-art biochemical, molecular, and cellular approaches to study DNA repair mechanisms and chemotherapy response. Data analysis and interpretation (35%) Collect, organize, and analyze experimental data. Maintain detailed laboratory records and ensure data integrity. Interpret findings and plan follow-up experiments. Manuscript and grant preparation (20%) Prepare figures and text for publications and grant proposals. Contribute to writing manuscripts, abstracts, and reports. Present findings in lab meetings, departmental seminars, and scientific conferences. Laboratory maintenance and compliance (10%) Assist in maintaining laboratory organization, equipment, and supply inventories. Ensure compliance with institutional safety and regulatory policies. Additional Job Description Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: ***************************************