Principal research scientist jobs in McNair, VA - 845 jobs

Are you searching for an opportunity to apply your engineering skills in a creative and collaborative laboratory environment? Would you love to engage in meaningful, hands-on work in the exciting field of optics with an employer that prioritizes impact, innovation, and personal development? If so, we're looking for someone like you to join our team at APL. We are seeking a creative Biophotonics Systems Scientist to join the Imaging Systems Group. As a member of our team, you'll contribute to critical system development and experimental efforts. You will be joining a multi-disciplinary team committed to crafting an environment of innovation. As a Biophotonics Systems Scientist, you will: Contribute to technical efforts in the development of biomedical and remote sensing systems from concept through the full life-cycle of development, test & evaluation to deployment. Assure execution of tasks, and quality and timeliness of technical products through the application of best engineering practices. Develop advanced algorithms and hardware for biomedical and remote sensing applications. Assist in the brainstorming and development of new initiatives/concepts in biophotonics, optical imaging, and related technologies through research and development efforts. Document technical contributions in internal memoranda/reports and conference/journal papers, as appropriate. Present findings and recommendations at appropriate internal and external forums. Qualifications You meet our minimum qualifications for the job if you... Possess a Master's in optical engineering, optical science, electrical engineering, imaging science, or other degree relevant to the work as described above. Have at least 4 years of demonstrated proficiency with optical or electronic hardware in a professional or academic environment. Knowledge and experience with basic circuit design and biophotonic systems development is a plus. Demonstrate a proven ability to work both independently and as part of a multidisciplinary team and possess strong interpersonal, speaking, and technical writing skills. Are able to obtain an Secret level clearance by your start date, and can ultimately obtain a TS/SCI clearance. If selected, you will be subject to a government security clearance investigation and must meet the requirements for access to classified information. Eligibility requirements include U.S. citizenship. You'll go above and beyond our minimum requirements if you... Possess a PhD in a relevant field Have 6+ years of relevant professional experience. Knowledge and experience with photonic integrated circuit design and/or test is a plus. Hold a TS+SCI level clearance. If selected, you will be subject to a government security clearance investigation and must meet the requirements for access to classified information. Eligibility requirements include U.S. citizenship. About Us Why Work at APL? The Johns Hopkins University Applied Physics Laboratory (APL) brings world-class expertise to our nation's most critical defense, security, space and science challenges. While we are dedicated to solving complex challenges and pioneering new technologies, what makes us truly outstanding is our culture. We offer a vibrant, welcoming atmosphere where you can bring your authentic self to work, continue to grow, and build strong connections with inspiring teammates. At APL, we celebrate our differences of perspectives and encourage creativity and bold, new ideas. Our employees enjoy generous benefits, including a robust education assistance program, unparalleled retirement contributions, and a healthy work/life balance. APL's campus is located in the Baltimore-Washington metro area. Learn more about our career opportunities at ****************************** All qualified applicants will receive consideration for employment without regard to race, creed, color, religion, sex, gender identity or expression, sexual orientation, national origin, age, physical or mental disability, genetic information, veteran status, occupation, marital or familial status, political opinion, personal appearance, or any other characteristic protected by applicable law. APL is committed to providing reasonable accommodation to individuals of all abilities, including those with disabilities. If you require a reasonable accommodation to participate in any part of the hiring process, please contact Accommodations@jhuapl.edu. The referenced pay range is based on JHU APL's good faith belief at the time of posting. Actual compensation may vary based on factors such as geographic location, work experience, market conditions, education/training and skill level with consideration for internal parity. For salaried employees scheduled to work less than 40 hours per week, annual salary will be prorated based on the number of hours worked. APL may offer bonuses or other forms of compensation per internal policy and/or contractual designation. Additional compensation may be provided in the form of a sign-on bonus, relocation benefits, locality allowance or discretionary payments for exceptional performance. APL provides eligible staff with a comprehensive benefits package including retirement plans, paid time off, medical, dental, vision, life insurance, short-term disability, long-term disability, flexible spending accounts, education assistance, and training and development. Applications are accepted on a rolling basis. Minimum Rate $100,000 Annually Maximum Rate $245,000 Annually

Novateur stands for Innovation. We value creativity, vision, collaboration, and above all, ambition to innovate. Novateur Research Solutions is an R&D firm located in Northern Virginia, developing intelligent systems that push the boundaries of computer vision, AI, and large-scale learning. We are hiring a Principal Research Scientist to lead cutting-edge programs in AI, computer vision, and intelligent systems. This role offers leadership opportunities to define new research directions and shape next-generation technologies. Responsibilities: • Serve as PI or co-PI on government-funded R&D programs. • Conceive, design, and oversee research in learning systems, spatiotemporal modeling, and geo-localization. • Publish, present, and contribute thought leadership to the AI community. • Mentor research staff and guide proposal development. Requirements: • PhD with 7+ years of research experience. • Demonstrated leadership in ML, vision, or scientific computing. • Record of funding, publications, and technical impact. • U.S. Citizen or Permanent Resident. Preferred: • Experience with multimodal learning, uncertainty quantification, or causal inference. Why Novateur? Join a team that values creativity and initiative. At Novateur, you'll lead transformative projects that redefine what's possible in intelligent systems. Company Benefits: Novateur offers competitive pay and benefits comparable to Fortune 500 companies that include a wide choice of healthcare options with generous company subsidy, 401(k) with generous employer match, paid holidays and paid time off increasing with tenure, and company paid short-term disability, long-term disability, and life insurance. We offer a work environment which fosters individual thinking along with collaboration opportunities within and beyond Novateur. In return, we expect a high level of performance and passion to deliver enduring results for our clients.

Job Category: Development Apply now Posted : November 5, 2025 Full-Time On-site Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe. The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization. Summary of Position The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams. Responsibilities and Job Duties: Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release. Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness. Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations. Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts. Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders. Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions. Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support. Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays. Author and/or review SOPs, technical protocols and reports, and regulatory filings. Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership. Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences. Participate in industry consortia on relevant topics and align internal strategies with industry practice. Qualifications Education & Experience Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development; or Master's degree with 12+ years of related industry experience; or Bachelor's degree with 14+ years of related industry experience 2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams Prior experience in preparing analytical sections of IND, BLA and regulatory responses. Knowledge, Skills and Abilities Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA) Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment Skilled in stakeholder management, with clear, proactive, and collaborative communication style Strong technical writing skills and attention to detail in documentation and data review Experience mentoring and developing scientific staff; promotes open communication and teamwork Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines. Demonstrated leadership and influence in cross‑functional matrix environments Preferred Qualifications Familiarity with potency assays, physiochemical assays and other characterization assays Knowledge in novel techniques on detecting and analyzing residual impurities Strong publication record and external scientific presence Experience in fostering partnership with clients through CDMO service Supervisory Responsibilities Yes. This role may supervise Associate Scientist and/or Scientist Additional Information The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits. The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law. Statement MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies. #J-18808-Ljbffr

Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data‑driven decision‑making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description: The Personalization team in AI Foundations builds and ships state‑of‑the‑art scalable architecture, AI/ML solutions for Capital One's award‑winning mobile app. We partner with product, tech and design teams to deliver app features that delight customers with dynamic and personalized experiences. You will be the driving force to experiment, innovate and create next generation experiences powered by the latest emerging AI/ML technologies. In this role, you will: Partner with a cross‑functional team of data scientists, software engineers, product managers, and designers to deliver AI‑powered products that customers love. Leverage a broad stack of technologies - PyTorch, Keras, TensorFlow, scikit‑learn, transformers, and more - to reveal the insights hidden within huge volumes of numeric and textual data. Build machine learning models through all phases of development, from design through training, evaluation, validation, and implementation. Flex your interpersonal skills to translate the complexity of your work into tangible business goals. The Ideal Candidate is: Customer first. You love the process of analyzing and creating, but also share our passion to do the right thing. You know at the end of the day it's about making the right decision for our customers. Innovative. You continually research and evaluate emerging technologies. You stay current on published state‑of‑the‑art methods, technologies, and applications in the area of deep learning, natural language processing and recommendation & personalization and seek out opportunities to apply them. Creative. You thrive on bringing definition to big, undefined problems. You love asking questions and pushing hard to find answers. You're not afraid to share a new idea. With an engineering mindset as shown by a track record of delivering models at scale both in terms of training data and inference volumes. Experience in delivering libraries, platform‑level code to existing products. A leader. You challenge conventional thinking and work with stakeholders to identify and improve the status quo. You're passionate about talent development for your own team and beyond. Basic Qualifications Currently has, or is in the process of obtaining one of the following with an expectation that the required degree will be obtained on or before the scheduled start date: A Bachelor's Degree in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) plus 5 years of experience performing data analytics. A Master's Degree in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) or an MBA with a quantitative concentration plus 3 years of experience performing data analytics. A Ph.D. in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field). Preferred Qualifications Master's Degree in “STEM” field (Science, Technology, Engineering, or Mathematics) plus 3 years of experience in data analytics, or Ph.D. in “STEM” field (Science, Technology, Engineering, or Mathematics). Specialized experience in the fields of Information Retrieval, NLP, Data‑centric AI, and Knowledge Graphs. At least 3 years' experience in PyTorch/Tensorflow. At least 3 years' experience with machine learning. At least 1 year of experience working with AWS. Capital One will consider sponsoring a new qualified applicant for employment authorization for this position. The minimum and maximum full‑time annual salaries for this role are listed below, by location. Please note that this salary information is solely for candidates hired to perform work within one of these locations, and refers to the amount Capital One is willing to pay at the time of this posting. Salaries for part‑time roles will be prorated based upon the agreed upon number of hours to be regularly worked. McLean, VA: $158,600 - $181,000 for Principal Associate, Data Science New York, NY: $173,000 - $197,400 for Principal Associate, Data Science San Jose, CA: $173,000 - $197,400 for Principal Associate, Data Science Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter. This role is also eligible to earn performance‑based incentive compensation, which may include cash bonus(es) and/or long term incentives (LTI). Incentives could be discretionary or non‑discretionary depending on the plan. Capital One offers a comprehensive, competitive, and inclusive set of health, financial and other benefits that support your total well‑being. Learn more at the Capital One Careers website. Eligibility varies based on full or part‑time status, exempt or non‑exempt status, and management level. This role is expected to accept applications for a minimum of 5 business days. No agencies please. Capital One is an equal‑opportunity employer (EOE, including disability/vet) committed to non‑discrimination in compliance with applicable federal, state, and local laws. Capital One promotes a drug‑free workplace. Capital One will consider for employment qualified applicants with a criminal history in a manner consistent with the requirements of applicable laws regarding criminal background inquiries, including, to the extent applicable, Article 23‑A of the New York Correction Law; San Francisco, California Police Code Article 49, Sections 4901‑4920; New York City's Fair Chance Act; Philadelphia's Fair Criminal Records Screening Act; and other applicable federal, state, and local laws and regulations regarding criminal background inquiries. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation, please contact Capital One Recruiting at 1‑************ or via email at RecruitingAccommodation@capitalone.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations. For technical support or questions about Capital One's recruiting process, please send an email to **********************. Capital One does not provide, endorse nor guarantee and is not liable for third‑party products, services, educational tools or other information available through this site. Capital One Financial is made up of several different entities. Please note that any position posted in Canada is for Capital One Canada, any position posted in the United Kingdom is for Capital One Europe and any position posted in the Philippines is for Capital One Philippines Service Corp. (COPSSC). #J-18808-Ljbffr

Cydecor is a premier Federal Government solutions provider, delivering differentiated innovations in mission systems and business platforms. We leverage leading-edge secure systems and software development, backed by industry-leading subject matter expertise, and business intelligence to enable decision-support and remain ahead of ever-evolving national security challenges. Our success rests squarely on three bedrock principles: People, our center of gravity; Mission, what inspires us; and an unyielding commitment to Excellence, what separates us. Job Description: We are seeking a Senior Decision Scientist that can understand and improve the judgment and decision making of individuals, groups, and organizations. This individual will apply principles of psychology to business, analytic and other decision making processes to improve and / or empirically evaluate those processes. Activities include assisting in policy planning; workflow procedures testing and evaluation, analytic workflow redesign, training and development. Partner with management to prescribe workflow modifications that improve worker productivity and analytic judgment. Work locations vary throughout the National Capital Region (NCR), with Reston, VA and Washington, DC being primary locations. Responsibilities include: Managing end-to-end data science projects, analyzing user behavior, and building models. Requires a blend of strong analytical and technical skills, with qualifications including a background in statistics, programming languages and familiarity with cloud platforms and data visualization tools. Develop and implement solutions: Apply advanced analytics, machine learning, and AI to create systems that support strategic decision-making. Data analysis and interpretation: Analyze large datasets, identify trends, and present findings to both technical and non-technical stakeholders. Experimentation and evaluation: Design, build, and analyze experiments to evaluate product features and performance. Product support: Partner with product teams to influence decisions, provide recommendations, and report on the state of the business and experiment results. Data management: Work with data infrastructure, including tools like Hadoop, Hive, and SQL, and automate analysis and pipelines. Here's what you need: Minimum 12 years of overall experience with at least a portion of the experience within the last 2 years reflecting the above areas of responsibilities. Master's degree OR a Bachelor's degree and an additional 5 years of related experience, for a total of 17 years, as a substitute for the Master's degree. Proven ability to work independently and with minimal oversight. Technical skills: Strong knowledge of statistics, including hypothesis testing and regression. Experience with big data technologies. Familiarity with data visualization tools. Experience with generative AI and large language models is a plus. Analytical and soft skills: Strong quantitative and analytical mindset. Excellent communication and presentation skills to explain complex findings. Ability to manage projects from start to finish. Security Clearance: Active TS/SCI Education: Master's degree or Bachelor's with 5 additional years of relevant experience. Work Schedule: Monday - Friday, 8 hours each day. Benefits: Cydecor offers a comprehensive compensation package including Health and Dental Insurance, Vision and Life Insurance, Short-Term & Long-Term Disability, 401(K) + company match, Paid Time Off (PTO), Paid Company Holidays, Tuition and Professional Development Assistance and more. What We Believe We have an unwavering commitment to diversity with the aim that every one of our people has a full sense of belonging within our organization. As a business imperative, every person at Cydecor has the responsibility to create and sustain an inclusive environment. Equal Employment Opportunity Statement Cydecor is an Equal Employment Opportunity/Affirmative Action Employer (EEO/AA). All employment and hiring decisions are based on qualifications, merit, and business needs without regard to race, religion, color, sexual orientation, nationality, gender, ethnic origin, disability, age, sex, gender identity & expression, veteran status, marital status, or any other characteristic protected by applicable law. If you are a qualified individual with a disability and/or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to access job openings or apply for a job on this site because of your disability. You can request assistance by contacting ************** or calling ************.

Manufactures cell and gene therapies for phase I and II clinical trials; (2) processes hematopoietic stem cell grafts for transplantation; (3) develops new cell therapies; (4) performs in-process and lot release testing of cell and gene therapies; (5) develops new assays to test cell and gene therapies; and (6) prepares chemistry, manufacturing, and controls (CMC) documents for investigational new drugs (IND) and summary data for annual reports to the Food and Drug Administration (FDA). ROLES / RESPONSIBILITES Build and optimize a robust cGMP compliant platform for generation, expansion and cryopreservation of autologous induced pluripotent stem cells (iPSCs) from peripheral blood derived CD34+ cells. Differentiate iPSCs to retinal pigment epithelial cells (RPE) to develop an iRPE patch for a phase I clinical trial to treat "dry" age related macular degeneration. Update and validate SOPs related to CD34 expansion, iPSC culturing, and RPE differentiation Manage a day to day operation of GMP facility Maintain iPSC colonies and freeze their early passages. GMP and aseptic culturing of iPCSs and differentiation of patient iPSCs into Retinal pigment epithelium (RPE) and maintenance of those RPE cultures. This work will include: Preparing media, supplements, and reagents needed cell culture work. Maintaining the cell culture room biosafety level 2 standards and maintaining aseptic conditions in cell culture flow hoods, incubators, and prepare sterile tools needed for work with cell cultures. The cell culture maintenance work will require working for short periods of times on the weekends and some holidays. Work to characterize the iPSC colonies for their pluripotency. This will require: Immunostaining of iPSCs, preparing RNA and cDNA from iPSCs, and Performing qRT-PCR assays. Additionally they will perform three germ layer assay based functional characterization of iPSCs. This work will also include any cell types that act as control for his iPSC work. Prepare regulatory documents for FDA and technology transfer Coordinate transfer of lab-technology to Good Manufacturing Practice (GMP suite) Develop Standard Operating Procedures (SOPs) with the Contract Research Organization (CRO) in relation to the cell therapy project. DESIRED BACKGROUND · Prior cell culture experience is required · Prior experience working in a cGMP environment is required

HANSOH BIO A U.S.-based research & development subsidiary of Hansoh Pharma, Hansoh Bio is a biotech devoted to discovering and developing breakthrough therapies that conquer serious diseases and disorders for patients around the world. Hansoh Pharma is a leading biopharmaceutical company in Asia. Founded in 1995, we are committed to discovering and developing life-changing medicines to help patients. Our rapidly growing workforce of 9,000+ employees, and our fully integrated research and development, manufacturing and commercial capabilities have propelled us into leadership positions across a broad range of therapeutic areas, including CNS, oncology, infectious disease, and metabolic disorders. With 1,400 professionals across multiple R&D functions, we rank 2nd in innovation among all Chinese biotech and pharmaceutical companies, based on new molecular entities developed for clinical development. Since an IPO on Hong Kong stock exchange in June 2019, we have raised $1.6B from global top-tier institutional investors; with a current equity value of approximately $27B, Hansoh is the 2nd largest biopharmaceutical companies in China and 6th largest in Asia by market capitalization. For more information, please visit **************** BIOTHERAPEUTICS - MARYLAND R&D CENTER At Hansoh, we never rest in the quest of bringing truly life-changing treatments to patients. We are currently seeking a motivated scientist to join our Biotherapeutics-ADC Biology team in Rockville, Maryland. The position offers an exciting opportunity to engage in target discovery, validation, and preclinical candidate development of high impact projects. THE POSITION -SCIENTIST OF BIOTHERAPEUTICS We are seeking a passionate, science-driven candidate to lead or contribute to antibody-based therapeutic projects at Hansoh Bio. The Maryland R&D site focuses on the discovery of novel drug candidates, including monoclonal antibodies, antibody-drug conjugates (ADCs), and bispecific antibodies for the treatment of cancer, renal, cardiovascular, and immune system diseases. The candidate is expected to explore and introduce new technological tools, methodologies, and knowledge to achieve project goals and expand our research capabilities. The successful candidate will collaborate directly with corporate partners, cross-functional teams, and project teams to support our preclinical programs. RESPONSIBILITIES Lead or support oncology, immuno-oncology and/or immunology projects. Design, conduct, and analyze experiments on antibody-drug conjugates (ADCs). Perform in vitro functional and binding assays. Culture, engineer cell lines, and prepare reagents. Troubleshoot experiments with technical discretion. Review data, prepare reports, and present findings to managers and teams. Collaborate with cross-functional teams to execute tasks. Maintain accurate documentation in electronic lab notebooks. QUALIFICATIONS Ph.D. in cancer biology or related field. Demonstrated innovation in oncology, immuno-oncology, or autoimmune disease research. Skilled in in vitro techniques, including culture, multicolor FACS, ELISA and/or in vitro killing assays. Experience with mouse tumor models. Background in pre-clinical assay development preferred. Excellent oral and written communication skills. Ability to deliver clear, precise reports in internal and external meetings. Strong record of impactful publications and/or patent contributions.

Kelly Government Solutions is seeking a Scientist - Downstream Process Development to work on-site with the Vaccine Production Program at the National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH) in Gaithersburg, MD. KEY TASKS/SERVICES (1) Support the Purification group of the Vaccine Production Program (VPP) Labs of the Vaccine Research Center (VRC). (2) Develop downstream (purification) processes, under the supervision of a project lead scientist, for recombinant proteins, virus vaccines, and virus-like particles (VLP) that may be used as clinical vaccine candidates. (3) Serve as a functional lead in chromatography process development unit operations. (4) Provide critical process step assessment and experimental design to define optimal process parameters for chromatography unit operations. (5) Train team members in large-scale unit operation such as AxiChrom column packing and Pilot-scale chromatography execution. (6) Work independently and collaboratively within the purification group to design, develop and optimize chromatography and filtration step unit operations to support process development of clinical trial vaccine candidates and mAb products. (7) Purify research-phase recombinant proteins, virus vaccines and/or virus-like particles in support of other groups at the VRC. (8) Work to prepare necessary materials (buffers, packed columns, etc.) in support of downstream process activities. (9) Perform protein/small molecule conjugation experiments to support method development or conjugate-based vaccine candidates. (10) Support technology transfer of processes to VRC Pilot Plant for manufacture of clinical products including authoring process descriptions, reports, and on-floor support. (11) Author training documents, process documents and summaries, instrument SOPs, technical reports, protocols, and other supporting documentation. KEY REQUIREMENTS (1) Ph.D. in Bioengineering, Chemical Engineering, Biochemistry, or related scientific discipline (2) Extensive experience in recombinant protein purification development for GMP clinical-phase products (3) Familiarity with monoclonal antibody and multi-specific antibodies, recombinant protein vaccine and nanoparticles; mRNA and mRNA/LNP vaccines.

Reality Labs at Meta is seeking Research Scientists with experience in product-focused machine learning and signal processing research to advance our pioneering work in neuromotor interfaces, which has grown out of the acquisition of CTRL-labs. We're building a practical interface drawing on the rich neuromotor signals that can be measured non-invasively via surface electromyography (EMG) with single motor neuron resolution. This technology could become one of the main pillars for interaction with virtual and augmented worlds.We are a multi-disciplinary team of researchers investigating the nature of human neuromotor signals, developing novel signal processing and machine learning methods to infer a user's intent, and creating novel interaction techniques and user experiences. Help us unleash human potential by removing the bottlenecks between user intent and action. **Required Skills:** Research Scientist - CTRL Labs Responsibilities: 1. Research and develop Deep Learning or other computational models 2. Design methods, tools and infrastructure to analyze and leverage rich multimodal data sets 3. Set technical direction for a project of 2-3 researchers and engineers 4. Help transition and deliver our work from research into product 5. Adapt standard machine learning methods to best leverage modern parallel environments (e.g. distributed clusters, multicore SMP, and GPU) **Minimum Qualifications:** Minimum Qualifications: 6. Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience 7. Ph.D. degree in Computer Science and Engineering, Electrical Engineering, Statistics/Mathematics 8. Experience with developing machine learning models at scale from inception to business impact 9. Programming experience in Python and hands-on experience with frameworks such as PyTorch 10. Exposure to architectural patterns of large scale software applications 11. Must obtain work authorization in the country of employment at the time of hire, and maintain ongoing work authorization during employment **Preferred Qualifications:** Preferred Qualifications: 12. Proven track record of achieving significant results as demonstrated by grants, fellowships, patents, as well as first-authored publications at peer-reviewed AI conferences (e.g. NeurIPS, CVPR, ICML, ICLR, ICCV, ACL, and ICASSP) 13. Demonstrated software engineer experience via an internship, work experience, coding competitions, or widely used contributions in open source repositories (e.g. GitHub) 14. Experience bringing machine learning-based products from research to production **Public Compensation:** $184,000/year to $257,000/year + benefits **Industry:** Internet **Equal Opportunity:** Meta is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, transgender status, sexual stereotypes, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. We also consider qualified applicants with criminal histories, consistent with applicable federal, state and local law. Meta participates in the E-Verify program in certain locations, as required by law. Please note that Meta may leverage artificial intelligence and machine learning technologies in connection with applications for employment. Meta is committed to providing reasonable accommodations for candidates with disabilities in our recruiting process. If you need any assistance or accommodations due to a disability, please let us know at accommodations-ext@fb.com.

Up To $1,000 Paid Depression Study! Those who Currently Experience At Least TWO Symptoms of Depression And the Current Depressive Episode Started More Than 4 Weeks Ago May Qualify For The Study!

Mid-Atlantic Permanente Medical Group (MAPMG) invites applications for the position of Research Scientist II (Infectious Disease Epidemiology/Health Services Research), which is an equivalent to an academic associate professor, to join the Mid-Atlantic Permanente Research Institute (MAPRI). This is a full-time position based in our regional office located in Capitol Hill, Washington D.C. with a hybrid work model. Reporting to the Director of Research Science, the Research Scientist II will design and implement major investigator-initiated health services and epidemiology-related research projects in the area of infectious diseases. You will also secure external funding through federal, foundation, or industry grants, and disseminate findings through peer-reviewed publications and conference presentations. The Research Scientist II may contribute to intramural projects relevant to MAPRI and MAPMG, providing assistance as needed for study design, analysis plans, and interpretation of results. Please note, this is not a basic research or bench science position. You can expect to: Develop an innovative research portfolio in infectious disease healthcare delivery and outcomes, working both independently and in collaboration with external partners, leveraging Kaiser Permanente's extensive clinical data Prepare and submit grant proposals and secure extramural research funding, aiming to achieve funding for 75-80% of annual effort within five years. Initiate and maintain collaborations with external partners, including federal agencies, other Kaiser Permanente regions, research networks, and academic or healthcare system partners. Publish one to two first-author papers and one to two collaborative papers annually, and present research findings (poster or oral) at national scientific meetings. Collaborate with MAPRI research teams (data analysts, project managers, and biostatisticians), leading research studies and ensuring they are completed successfully Mentor MAPMG staff, physician researchers, and research interns. Contribute to the scientific community through being a peer reviewer for journals (at least two per year) and participating in expert or grant review panels. What is required: MD/DO with an additional advanced research degree (e.g., MPH, MAS, MS, PhD) OR a PhD or equivalent degree in Epidemiology, Health Services Research, Nursing, or related discipline is required Extensive experience in infectious disease research Minimum of seven (7) years of post-doctoral research experience in epidemiology, health services research, or related field is required; experience in a health system research setting preferred Strong publication record in peer-reviewed journals Demonstrated ability to design and lead simultaneous original research studies and publish results. Successful track record of extramural grant funding as Principal Investigator Must be able to go into the regional office located in Capitol Hill, Washington D.C. at least quarterly, and on an as-needed basis Candidates must either currently live in or be willing to relocate to the Washington D.C., Maryland, or Virginia area Must provide documentation of the Covid vaccine 2-dose series (or J&J 1-dose) prior to October 1, 2023, or documentation for 1-dose of the most current Covid vaccine (Pfizer or Moderna) as a condition of employment. Must provide documentation for the influenza vaccine as a condition of employment. Competitive Benefits: Competitive compensation package 100% employer-funded medical and dental insurance premiums for employees and families Generous paid time off, including vacation, holidays, and sick leave, plus maternity and parental leave Pension plan, and 401(k) retirement plan with employer contributions Life insurance, short-term disability, and long-term disability coverage Education reimbursement The starting annual salary for this position ranges from $152,776.24 to $190,970.12 depending on circumstances including an applicant's skills and qualifications, certain degrees and certifications, prior job experience, training, market data, and other relevant factors. In addition to the salary range above, MAPMG offers rich benefits that add substantial value to the total compensation package. MAPMG continuously works to identify and mitigate healthcare inequities, and that starts with providing an inclusive, supportive environment for our physicians and staff. We encourage applicants of any race, color, religion, sex, sexual orientation, gender identity, or national origin who value diversity and will commit to practicing culturally competent healthcare. External hires must pass a background check and drug screening.

Responsibilities The Senior AI Planning Research Scientist will solve hard, real-world planning problems requiring nothing less than state-of-the-art solutions. You'll take responsibility for accomplishing specific deliverables within a small team setting of fellow engineers. You'll communicate and collaborate with fellow team members and help guide junior staff. Peraton Labs generates transformative applied research to fuel solutions for our customer's unique challenges. We are a self-sustaining research center within Peraton that provides applied research and engineering to enable government agencies, utilities, and commercial enterprises to fully exploit the future of communications, analytics, and cyber security. Who we're looking for: Cyber: We are looking for staff with a strong interest (and ideally a track record) in cybersecurity research and development. Generalists: You should have a breadth of knowledge across multiple domains. You'll typically focus your work on the domain(s) of your specialty or preference, but a strong multi-domain awareness and ability is required. You should have a curiosity to learn new technology. Tangible: You'll work on applied research programs to conceive and develop prototypes to solve cutting-edge, complex problems. Qualifications Education Requirements: Requires 5 years with BS/BA, 3 years with MS/MA, or 0 years with PhD Additional relevant experience will be considered in lieu of formal education Skills and Experience You Should Possess: Experience developing and deploying sophisticated AI planning solutions Expertise in common AI planning approaches such as behavior trees, GOAP, HTN, etc. Expertise in one or more system languages: C, C++, Go, etc. Expertise in Python Expertise in designing, developing, and testing software modules related to emerging embedded cyber capabilities, high-availability network protocols, cyber mission planning, and reasoning systems. Modern development practices and toolsets (Git, subversion, CI/CD toolchains) Experience running docker containers Experience developing in Linux A passion to learn something new every day and to stay up-to-date with developments in your field Adept at independent problem-solving and comfortable with a general approach of taking initiative to find and develop solutions US Citizenship Required Additional Desired Skills: Ability to grasp the “big picture” and see beyond specific problems Network emulation frameworks including CORE, EMANE, MiniNet Experience with Networking Protocols Familiarity with one or more assembly languages (x86/64, ARM, MIPS, etc.) Experience with configuring Network appliances Experience with threat intelligence research Minimum Clearance Required: Active Top Secret, able to obtain TS/SCI Peraton Overview Peraton is a next-generation national security company that drives missions of consequence spanning the globe and extending to the farthest reaches of the galaxy. As the world's leading mission capability integrator and transformative enterprise IT provider, we deliver trusted, highly differentiated solutions and technologies to protect our nation and allies. Peraton operates at the critical nexus between traditional and nontraditional threats across all domains: land, sea, space, air, and cyberspace. The company serves as a valued partner to essential government agencies and supports every branch of the U.S. armed forces. Each day, our employees do the can't be done by solving the most daunting challenges facing our customers. Visit peraton.com to learn how we're keeping people around the world safe and secure. Target Salary Range $112,000 - $179,000. This represents the typical salary range for this position. Salary is determined by various factors, including but not limited to, the scope and responsibilities of the position, the individual's experience, education, knowledge, skills, and competencies, as well as geographic location and business and contract considerations. Depending on the position, employees may be eligible for overtime, shift differential, and a discretionary bonus in addition to base pay. EEO EEO: Equal opportunity employer, including disability and protected veterans, or other characteristics protected by law.

Research Scientist - Robotics, Dynamic Systems, and Control The Robotics and Electromechanical Systems (REMS) group at Intelligent Automation, Inc. (IAI) has an open full-time position for a Research Scientist. We are looking for a self-motivated individual who is interested in advancing state-of-the-art robotics technologies. At IAI, you will be working with multi-disciplinary teams of research scientists, engineers, and project managers to develop custom solutions to various challenging problems in the fields of Robotics, Machine Learning, and Artificial Intelligence. ABOUT IAI: Intelligent Automation, Inc. (IAI) is a technology innovation company headquartered in Rockville, MD, conducts state of the art research and product development in the areas of Robotics, Signal Processing and Control, Sensor Technology, Distributed Intelligent Systems and other areas (visit *************** We specialize in providing advanced technology solutions and R&D services to federal agencies, and corporations throughout the United States and internationally. IAI's core R&D areas include: Air Traffic Management, Big Data and Social Media Analytics, Control and Signal Processing, Cyber Security, Education and Training Technologies, Health Technologies, Modeling and Simulation, Networks and Communications, Robotics and Sensor Systems. For more information on IAI, please visit ************** CITIZENSHIP / IMMIGRATION STATUS: We can only accept applicants that are either US Citizens or US Permanent Residents (Green Card). JOB DUTIES: • Develop innovative solutions for challenging robotic control problems that the REMS group is working on • Support ongoing research projects by collaboratively conducting trade studies, designing and implementing functional systems, testing and demonstrating the capabilities, and writing reports • Support capturing of next robotics funding opportunities by collaboratively producing and submitting proposals that are unique and very innovative REQUIRED EDUCATION & EXPERIENCE: • Ph.D. or M.S. in Robotics, Mechanical Engineering (Dynamics and Control), Computer Science (or a related field) • Minimum 3 years of experience working on robotic control problems in a research laboratory environment • Programming experience using a physics engine such as ODE, Bullet, etc. • Programming experience using ROS and/or a similar robotic control framework REQUIRED SKILLS: • Solid understanding of kinematics and dynamics, probabilistic robotics and object-oriented programming • Ability to implement prototype software algorithms based on conference/journal publications • Proficient technical writing and strong communication skills DESIRED EXPERIENCE/SKILLS: • Solid understanding of machine learning including deep learning and reinforcement learning • Solid understanding of classical artificial intelligence and behavior-based robotics • Experience with a robotics simulation framework such as Gazebo, Unity, and AirSim • Publication of peer-reviewed technical papers All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status. IAI is an EEO/AA employer.

Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.

Full-time Description Formulation Scientist/Senior Scientist Under general direction, manages, plans, and executes projects for product development. Under limited direction and supervision, carries out design and development of solid oral dosage forms using quality by design (QbD concept) through ANDA filing and/or product launch. Under limited direction and supervision, carries out design and development of complex oral dosage forms using QbD concepts through ANDA filing and/or product launch. Develops and executes formulation strategies related to product development (i.e., project planning and timelines, experimental design, data evaluation, formulation of relevant and scientifically based conclusions Coordinates studies with other technical groups (i.e., Analytical Sciences, Biopharmaceutics, Legal, Regulatory & Tech Services). Maintains a high level of expertise within the field and develops new technologies and concepts to be applied in the development of oral controlled release drug products. Participates as a project leader, manager and/or ad hoc member in Product Development efforts, and identifies, analyzes and suggests corrective actions to optimize R&D processes, technology and regulatory compliance issues. Principal Accountabilities JOB DUTIES & RESPONSIBILITIES Developing pharmaceutical products, leading to successful ANDA filings and approval in a timely manner. Managing and scheduling multiple projects, setting objectives, prioritizing activities to meet the milestones in a fast-paced environment. Designing, formulation and process development for various drug from project initiation to commercialization by following appropriate GMP regulations and safety requirements. Participate in the set-up and operation of pilot scale equipment and instrumentation for the completion of small production runs in collaboration with the R&D technician. Design and conduct pre-formulation and formulation studies, process development and optimization of prescription dosage form designs and ANDA oral Dosage forms using DOE Perform Literature search and Evaluate patents to develop non-infringing strategies Preparation of product manufacturing, batch records and protocols for different product development stages, including from R&D prototype formulations to process validations following SOPs and procedures, ensuring the detailed record and data keeping. Utilize formulation techniques, processing equipment and unit operations including Wurster Coating, Tablet Coating, Compression, Blending, Encapsulation, HPLC, Spectrophotometry, Dissolution, Viscometer to develop Bio-Equivalent products Review Analytical Data, draft SOP's, Process Evaluation protocols, IQ, OQ, PQ protocols and GMP Manufacturing Batch records, Packaging Batch Records. Characterization of APIs, excipients and in process products; analysis of in-process samples or in-process products based on protocols and QbD concept, preparing various formulation samples to support cross-functional programs as needs. Completes documentation associated with manufacturing processes (e.g. batch record, protocols, and logbooks) with detail and accuracy. Establishing documentation management systems for CMC development and meeting FDA GMP, regulatory requirement, and FDA onsite inspections. Comprehensive knowledge of IVIVC, QbD and Design of Experiments (DOE). Ensuring all regulatory documents in compliance with SOPs, FDA Regulations, and cGMP policy where applicable. Knowledge of manufacturing regulatory programs and objectives (cGMP, CFR 210 and 211). Maintaining compliance with GMP, SOPs and DEA regulations. Coordinate with Regulatory Affairs, Operations, QC/QA and Supply Departments to ensure that projects are planned and executed in a timely manner. Management Responsibility The Senior Scientist leads the assigned projects and guides the operation of the product development ranging from selection of staff, choice of methods, purchase of equipment, quality assurance, quality control, safety, hours of operation, scheduling of staff, and utilization management. Reports to Sr. Vice President, R&D Requirements Minimum Requirements Knowledge & Skills Good communication skills, critical thinking, flexibility, time management, self-motivation. Minimum Experience & Education Ph.D. in pharmaceutical sciences with minimum of 2 years' experience OR; Masters in pharmaceutical sciences with minimum of 5 year' experience in generic product development, with emphasis in solid/liquid orals or an equivalent combination of education and experience. Disclaimer: The above information on this description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.

Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: At MilliporeSigma, as a Scientist 2 - Analytical Development, you will be the primary scientific resource for a given study with the Product Characterization Laboratory in our Biologics department. The Scientist will act as subject matter expert in analytical method development/validation and feasibility/transfer for testing required to manufacture clinical and commercial products. * Understand GMP requirements for validation/transfer and documentation * Act as subject matter expert (SME) in analytical methods and provide guidance to analysts and study managers. * Apply laboratory techniques and skills to complete experiments designed to address a variety of specific problems. * Lead development/validation and feasibility/transfer of analytical methods and ensure timely initiation and completion of studies. * Prepare/ review protocols, reports, SOPs, laboratory records, tech specifications, and other related documents. * Execute analytical methods in the lab for assay development/validation, feasibility/transfer. * Perform testing in accordance with SOPs and regulations (cGMP) * Transfer GMP assays to the routine team and provide training to the analysts, study managers, report writers and QA. * Operates, maintains lab equipment as required by SOPs and testing procedures. * Utilize applicable computer programs during testing and routine tasks (i.e. Word, Excel, Oracle, LIMS, BRIQS, etc) * Lead general change control and resolve deviations by completing event records * Contribute ideas and suggestions to improve standard laboratory techniques, protocols, processes, and equipment * Ensure current regulatory requirements and technical needs of internal and external clients are appropriately met. * Maintain strong communication skills to effectively interact with internally and externally stakeholders. * Engage directly with clients. * Performs other duties as assigned. Who You Are Minimum Qualifications: * Ph.D. in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 3+ years relevant experience -OR- * Master's Degree in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 5+ years relevant experience -OR- * Bachelor's Degree in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 7+ years industry experience Preferred Qualifications: * Experience with some or all of the following technical disciplines: * Liquid Chromatography (SEC, RP, IEX, etc.), * Mass Spectrometry (Intact Molecular weight, Peptide mapping, Disulfide mapping, Glycan Profiling, N-/C-Terminal Sequencing) * Capillary Electrophoresis Methods (CE-SDS, cIEF) * Compendial assays, etc. * Broad working knowledge of filed and experience with relevant laboratory practices, techniques, equipment, materials and mathematical calculations. * Intermediate skills in applicable computer programs. * Experience of method development in a pharmaceutical laboratory or similar field. * Excellent verbal and written communication skills that have been demonstrated through presentations/seminars, oversight of projects, implementation of new services, etc. * Excellent time management skills. * Demonstrates a high level of initiative and leadership capabilities. * Effective coaching and training skills for complex and highly technical work. Pay Range for this position - $75,400 - $131,400 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Come join our family! Microbac Laboratories is an essential business offering competitive pay and benefits including medical, dental, vision, life insurance, disability, generous paid time off including vacation, holidays and flex-time, a wellness program, referral bonus, tuition reimbursement and more! Whether you are just starting your career in science or looking to further it, Microbac will put you on the path of an exciting career with room to grow. Quality, safety, giving back to our communities, diversity and inclusion, customer success and employee wellbeing are part of our core culture. We are looking for motivated individuals to join our family as an Associate Scientist I . ABOUT MICROBAC Microbac Laboratories, Inc. is a premier commercial laboratory testing firm that partners with clients worldwide, offering laboratory solutions to the life science, food and nutrition, and environmental industries and serves our clients with the utmost expertise and respect for their market requirements, constraints, and challenges. We embody a company-wide commitment to exceptional customer experience, which has been refined over nearly 50 years of trusted, analytical and measurement experience. Through our network of laboratories, offices, and field services, we have the flexibility to meet the unique requirements for each client, project, and scope. As a privately held third-party testing company, Microbac operates with a commitment to safety, quality, and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and nutrition and life science markets. JOB SUMMARY The Associate Scientist I, working in an accredited commercial laboratory, is responsible for assisting with the conduct of microbiological assays and associated activities to determine antimicrobial efficacy of household and commercial cleaning products. ESSENTIAL FUNCTIONS: Following established SOP's and adhering to state, federal and other accrediting body requirements, collect information about the antimicrobial properties of substances/samples to support the analytical testing needs of our clients for such purposes as quantitative or qualitative analysis, and product development Perform laboratory housekeeping duties to include autoclaving and glassware processing Prepare necessary standards, solutions, reagents, media, etc., required for sample analyses Perform equipment and instrumentation set up Operate basic and specialized laboratory instrumentation Prepare and analyze samples Accurately record observations and data and interpret results Assists in the development and validation of new analytical methods Assists in the development of new laboratory procedures Assist department supervisors and managers with staff training Sign off on final certificates of analysis Contribute to writing, editing, and reviewing SOP's Monitor and address sample backlog issues Perform peer review of data to ensure accuracy Maintain accurate, up to date logs, notebooks, and equipment records Perform necessary laboratory administrative functions such as filing paperwork, photocopying, reviewing of data, and entering data into computerized LIMS Comply with and promote Personnel, Safety, and Quality Program MINIMUM REQUIREMENTS: Bachelor's degree from a four-year accredited institution in a related field of applied science Prior analytical testing experience Above average knowledge of principles, terminology, practices, techniques, and instrumentation commonly used in a laboratory setting Ability to interpret data and prepare reports Ability to effectively prioritize work and manage time to meet deadlines and rush orders Computer literacy Ability to work with delicate laboratory equipment Ability to communicate effectively in both written and verbal formats WORKING CONDITIONS AND PHYSICAL REQUIREMENTS: The physical demands and working conditions described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Physical Requirements: While performing the duties of this job, the employee is regularly required to use hands to finger, handle, or feel objects, tools; talk or hear. The employee is required to stand, walk, and sit. The employee must regularly lift and/or move up to 25 pounds. Specific vision abilities required by this job include color vision and depth perception. Working Conditions: While performing the duties of this job, the employee will be in a general laboratory and office environment. The noise level in the work environment is usually moderate. This job may require travel less than 20% As a privately held third-party testing company, Microbac operates with a commitment to safety, quality and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and life science markets. OTHER: This is not an exhaustive list of all duties an employee may be required to perform. Microbac reserves the right to revise the job description at any time. Employment is at-will. Microbac, promotes a drug-free, alcohol-free workplace. Applicants considered for hire must pass a drug test before beginning work. Refusal to submit to testing will result in disqualification of further employment consideration. Microbac is an Equal Opportunity Employer - We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. All qualified applicants will receive consideration for employment.

Formulation Scientist/Senior Scientist Under general direction, manages, plans, and executes projects for product development. Under limited direction and supervision, carries out design and development of solid oral dosage forms using quality by design (QbD concept) through ANDA filing and/or product launch. Under limited direction and supervision, carries out design and development of complex oral dosage forms using QbD concepts through ANDA filing and/or product launch. Develops and executes formulation strategies related to product development (i.e., project planning and timelines, experimental design, data evaluation, formulation of relevant and scientifically based conclusions Coordinates studies with other technical groups (i.e., Analytical Sciences, Biopharmaceutics, Legal, Regulatory & Tech Services). Maintains a high level of expertise within the field and develops new technologies and concepts to be applied in the development of oral controlled release drug products. Participates as a project leader, manager and/or ad hoc member in Product Development efforts, and identifies, analyzes and suggests corrective actions to optimize R&D processes, technology and regulatory compliance issues. Principal Accountabilities JOB DUTIES & RESPONSIBILITIES Developing pharmaceutical products, leading to successful ANDA filings and approval in a timely manner. Managing and scheduling multiple projects, setting objectives, prioritizing activities to meet the milestones in a fast-paced environment. Designing, formulation and process development for various drug from project initiation to commercialization by following appropriate GMP regulations and safety requirements. Participate in the set-up and operation of pilot scale equipment and instrumentation for the completion of small production runs in collaboration with the R&D technician. Design and conduct pre-formulation and formulation studies, process development and optimization of prescription dosage form designs and ANDA oral Dosage forms using DOE Perform Literature search and Evaluate patents to develop non-infringing strategies Preparation of product manufacturing, batch records and protocols for different product development stages, including from R&D prototype formulations to process validations following SOPs and procedures, ensuring the detailed record and data keeping. Utilize formulation techniques, processing equipment and unit operations including Wurster Coating, Tablet Coating, Compression, Blending, Encapsulation, HPLC, Spectrophotometry, Dissolution, Viscometer to develop Bio-Equivalent products Review Analytical Data, draft SOP's, Process Evaluation protocols, IQ, OQ, PQ protocols and GMP Manufacturing Batch records, Packaging Batch Records. Characterization of APIs, excipients and in process products; analysis of in-process samples or in-process products based on protocols and QbD concept, preparing various formulation samples to support cross-functional programs as needs. Completes documentation associated with manufacturing processes (e.g. batch record, protocols, and logbooks) with detail and accuracy. Establishing documentation management systems for CMC development and meeting FDA GMP, regulatory requirement, and FDA onsite inspections. Comprehensive knowledge of IVIVC, QbD and Design of Experiments (DOE). Ensuring all regulatory documents in compliance with SOPs, FDA Regulations, and cGMP policy where applicable. Knowledge of manufacturing regulatory programs and objectives (cGMP, CFR 210 and 211). Maintaining compliance with GMP, SOPs and DEA regulations. Coordinate with Regulatory Affairs, Operations, QC/QA and Supply Departments to ensure that projects are planned and executed in a timely manner. Management Responsibility The Senior Scientist leads the assigned projects and guides the operation of the product development ranging from selection of staff, choice of methods, purchase of equipment, quality assurance, quality control, safety, hours of operation, scheduling of staff, and utilization management. Reports to Sr. Vice President, R&D Requirements Minimum Requirements Knowledge & Skills Good communication skills, critical thinking, flexibility, time management, self-motivation. Minimum Experience & Education Ph.D. in pharmaceutical sciences with minimum of 2 years' experience OR; Masters in pharmaceutical sciences with minimum of 5 year' experience in generic product development, with emphasis in solid/liquid orals or an equivalent combination of education and experience. Disclaimer: The above information on this description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.

Develop and implement protocols to receive and process multiple clinical trial and laboratory specimens weekly from NCI clinical and animal protocols. Develop customized programs for cataloging, storing, and tracking use and disposal of valuable human clinical and laboratory specimens in multiple ultralow and liquid nitrogen freezers utilizing Freezerworks. Provide annual reports of all human specimens as required. Develop and perform protocols for processing of bloods and tissue collected from clinical trials into single cell suspensions. Develop and troubleshoot protocols to extract T-cells and other tumor cell populations from patient samples for single cell transcriptome sequencing, flow cytometric analysis, and functional studies such as Elispot and cytotoxicity assays. Develop, troubleshoot and standardize protocols to culture and expand extracted T-cells. Develop and perform new molecular assays on human clinical trial specimens using new platforms, such as single cell sequencing. Develop, troubleshoot and perform multispectral immunofluorescence microscopy assays on human and murine specimens. Develop and perform multicolor flow cytometric assays on human clinical trial specimens. Design experiments and perform animal (murine) studies involving animal handling, tumor cell transplantation, immune cell depletion or administration, tumor measurements, and standardize treatment techniques such as intraperitoneal injections, IV tail vein injections and oral gavage. Develop, troubleshoot and perform sterile cell culture techniques such as maintaining and expanding immortalized cell lines. With minimal guidance, independently design and perform laboratory-based immunology and preclinical animal studies. Maintain records of all experiments in laboratory notebook, including planning, execution, outcome and evaluation of experiments performed. Collect, independently analyze and interpret data; perform appropriate statistical analyses and prepare data Prepare Quote Response for authorship of manuscripts. Establish and maintain stocks of valuable cancer cell lines in liquid nitrogen and keep an updated inventory. Prepare, maintain and catalog recombinant DNA stocks, plasmids and vectors, flow cytometry antibody stocks, and tissue bio-specimens. Attend clinical team meetings to prepare for receipt and management of biospecimens. Attend laboratory meetings and present results of independently performed research to staff. Analyze data and prepare presentations for NIH, regional and national meetings. Operate and troubleshoot laboratory equipment. Notify principal investigator of any general lab issues that are potentially problematic, so that changes can be made Work Location: National Institutes of Health 9000 Rockville Pike, Bethesda, MD 20892