Principal research scientist job in Saint Louis, MO
Scheduled Hours 40 The Magee lab studies the mechanisms that regulate childhood blood development and genetic changes that cause leukemia in children. We have several projects related to these general topics. Each focuses on gene regulation - and changes that occur in gene regulation - during stem cell development and differentiation. We use mice to model pediatric malignancies. The overall goal of our work is to develop new treatments for children with leukemia and other blood disorders.
Collaborates on designing, conducting and reporting of research projects.
Job Description
Primary Duties & Responsibilities:
* Collaborates on designing, conducting and reporting of research projects.
* Assists with grant preparation and reporting. May submit grant proposals in rare circumstances with the approval of the PI, Department Head and Dean.
* Prepares and submits papers on research.
* Develops hypotheses to be tested and ways of testing it.
* Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.
* Manages research project with other institutions and investigators.
* Performs other duties as assigned.
Working Conditions:
* Works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards.
* Must be physically able to wear protective equipment and to provide standard care to research animals.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education.
Certifications/Professional Licenses:
No specific certification/professional license is required for this position.
Work Experience:
Postdoctoral (3 Years)
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
Preferred Qualifications:
* Ph.D. or M.D./Ph.D. in biological sciences or related fields, as well as relevant postdoctoral experience. This should include molecular biology, flow cytometry, cell culture and ideally management of pluripotent cell culture lines.
* Experience mentoring students and colleagues is strongly preferred.
* Good spoken and written communication skills is strongly preferred.
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications/Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Analytical Problem Solving, Laboratory Instrumentation, Laboratory Processes, Laboratory Techniques, Oral Communications, Teamwork, Working Independently, Written Communication
Grade
R12
Salary Range
$63,400.00 - $115,000.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email **************************** or call the dedicated accommodation inquiry number at ************ and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
* Up to 22 days of vacation, 10 recognized holidays, and sick time.
* Competitive health insurance packages with priority appointments and lower copays/coinsurance.
* Take advantage of our free Metro transit U-Pass for eligible employees.
* WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
* Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
* We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We've got you covered.
* WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: ******************************
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University's policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Washington University is dedicated to building a community of individuals who are committed to contributing to an inclusive environment - fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.
$63.4k-115k yearly Auto-Apply 24d ago
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Principal/Senior Principal Scientist in Medicinal Chemistry
Humanwell Pharmaceutical Us
Principal research scientist job in Ballwin, MO
Humanwell Pharmaceutical US, Inc. is a St. Louis, MO-based pharmaceutical research and development company focused on creating novel therapeutics to address unmet medical needs. At Humanwell, we strive to improve patients' quality of life and are dedicated to building a happier and healthier world.
We are currently seeking a highly motivated Medicinal Chemistry Leader with broad drug discovery expertise, proven project management skills, and a strong track record of leading teams. This individual will play a pivotal role in our Drug Discovery Department, directing multidisciplinary efforts to identify innovative clinical candidates. Primary Responsibilities
Lead a multidisciplinary drug discovery team to ensure scientific excellence and operational efficiency.
Design and implement medicinal chemistry strategies that incorporate structural, physicochemical, pharmacokinetic, and safety considerations to drive discovery of novel and differentiated development candidates.
Evaluate and refine design proposals from the computational chemistry group.
Direct and execute synthetic chemistry strategies to support discovery efforts.
Identify and apply emerging synthetic and purification technologies to enable efficient synthesis of novel compounds.
Assess and recommend cutting-edge technologies in drug design and discovery.
Oversee and manage external CRO relationships to ensure seamless, high-quality project execution.
Collaborate effectively with leadership and provide timely, well-organized reports.
Facilitate effective communication and interaction across functions including computational chemistry, biology, CMC, safety, and external collaborators.
Lead preclinical studies and support IND filings.
Establish intellectual property strategies for discovery programs and drive patent preparation in partnership with patent counsel.
Required Qualifications
Ph.D. in Organic or Medicinal Chemistry and at least 15+ years of industrial drug discovery experience with a strong track record of scientific innovation and clinical candidate delivery.
Demonstrated leadership of cross-functional drug discovery teams.
Broad knowledge of medicinal chemistry and related disciplines (computational chemistry, DMPK, pharmacology, and process chemistry) to progress programs from lead identification to development candidate and IND filing.
Experience with cyclic peptide design, PROTAC and Molecular Glue will be preferred.
Experience managing timelines and external chemistry resources to meet key decision points with high-quality outcomes.
Ability to develop and maintain collaborative relationships across cultures, geographies, and organizations.
Proven creativity, problem-solving, and relationship-management skills within matrix teams (internal and external).
Self-driven, entrepreneurial mindset with demonstrated success working in fast-paced, diverse teams.
Hands-on experience using computational chemistry tools and structure-based drug design principles for lead identification and optimization.
Strong background in synthetic and medicinal chemistry, evidenced by high-quality publications and/or patents.
Demonstrated ability to lead programs from initiation through lead optimization to clinical lead selection.
Excellent organizational, interpersonal, and motivational skills to inspire and guide team members.
Clear, effective communication skills to present project strategies and progress to internal and external stakeholders; ability to communicate in both English and Chinese is preferred.
Why Join Us?
This is a unique opportunity to lead and innovate in a collaborative, fast-paced environment. You will play a pivotal role in shaping our medicinal chemistry strategy, advancing our pipeline, and translating cutting-edge science into transformative therapies for patients.
We offer a competitive salary and benefits package, including health insurance, 401K, and a vacation plan. Our company is committed to diversity and inclusion, and we welcome candidates of all backgrounds to apply.
If you are interested in this position, please submit your resume and a cover letter highlighting your relevant experience and qualifications.
$71k-105k yearly est. 60d+ ago
Sr Scientist/ Principal Investigator- Oligonucleotide Bioanalysis
RPM Research 4.5
Principal research scientist job in Saint Louis, MO
Job Description
Title
Senior Scientist/ Principal Investigator -Oligonucleotide Bioanalysis
We are inviting an accomplished scientist to join our growing drug discovery DMPK and Small Molecule Bioanalysis team. Our site has grown to 120 employees and our team has grown to 8 scientists. We have developed a collaborative culture and mutual respect. Our site is part of a 2400 person growing publicly traded international organization with over 15 sites. We recently made a $4.5MM investment in our site.
The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology, and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
This position will be part of a newly created group at our site supporting groups at another site. In the beginning, there will be one person at the site. The goal is to grow the group and this would become a contributing leadership position of the newly formed group.
Objectives:
Independently designs and implements novel Bio/-analytical methods to support research projects relating to the development of antisense or si RNA Oligonucleotide based therapeutics.
Develop and implement innovative high-resolution mass spectrometry-bases metabolite profiling and identification assays.
Act as an oligonucleotide bio/-analytical SME and work cross-functionally to build internal capabilities.
Position Requirements
Education and experience
BS or equivalent degree in Chemistry, Biochemistry, or related field, and greater than 15 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management or,
MS in Chemistry, Biochemistry, or related field, and 7 to 10 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management or,
Ph.D. in Chemistry, Biochemistry, or related field and 3 to 5 years of Analytical and/or Bioanalytical Chemistry laboratory experience including study management
5-10 years specific experience with Oligonucleotides
Skills and abilities
Proven track record of scientific contributions in the development of oligonucleotide analytical and bioanalytical methods to support oligonucleotide delivery platform development.
Demonstrates inter-disciplinary knowledge of drug discovery (in vitro/ in vivo pharmacology, ADME, PK/PD, translational research, and toxicology)
Working knowledge and awareness of general laboratory procedures.
Displays versatility and accuracy performing laboratory operations, some of which may be difficult and/or non-routine.
Strong and effective manager and mentor of junior scientists
Ability to use a computer to compile and maintain databases for records and inventory, utilizing the appropriate software.
Ability to adhere to all safety regulations and procedures.
In-depth knowledge and specific understanding of analytical testing needed in drug discovery as it relates to quantitating, characterizing, and further understanding the metabolic fate of ASO and si RNA-based therapeutics and conjugates thereof.
Support LC-MS instruments operation, daily maintenance, and troubleshooting.
An attitude for quality, an eye for detail, the ability to follow written instructions and work with a minimum of supervision.
Full and comprehensive benefits package including Medical/Dental/Vision insurance, 401k, bonus potential, and vacation.
This role is a full-time permanent position.
$73k-109k yearly est. 25d ago
Principal Scientist - Biotransformation
Bas Evansville 4.2
Principal research scientist job in Saint Louis, MO
The PrincipalScientist of Biotransformation will assist with the identification of enzymatic pathways that metabolize drug candidates in preclinical in vitro and in vivo models, including human tissue and cellular models (e.g., P450, non P450/AO/FMO, conjugative/UGT). Working primarily with preclinical species and human tissues/organ subcellular fractions, the individual will utilize contemporary mass spectrometry techniques (LC-MS/MS) to identify and elucidate the structures of drug metabolites (small molecules, peptides, oligonucleotides). The individual will contribute to the development of in vitro-to-in vivo relationships related to drug clearance & half-life predictions. The individual will collaborate with Pharmacology and Toxicology laboratory leadership to establish Novel Approach Methodologies (NAMs) to address mechanistic inquiries and/or platform screening processes for same.
Join us in embracing research and science to impact the health and well-being of people all over the world.
Essential Duties and Responsibilities
Design and execute laboratory studies aimed at identifying the enzymatic pathways that metabolize small molecule, peptide, and oligonucleotide therapeutics employing a contemporary approach methodology to establish the primary enzyme(s) contributing to the in vitro metabolism of a drug candidate(s).
Design and execute laboratory studies to elucidate primary drug clearance mechanisms in vitro, employing contemporary approach methodology to establish in vitro to in vivo correlations for anticipated drug clearance towards the prediction of human half life.
Design and collaborate with in vivo pharmacology & toxicology team members to execute ADME studies (
non radiolabeled
); elucidating the disposition of drug candidate molecules as it pertains to absorption, distribution, metabolism, and excretion; supplementing with in vitro protein binding, and blood distribution
For oligonucleotide and peptide molecules, design and execute in vitro studies aimed at elucidating the exonuclease/endonuclease and peptidase(s) metabolism of drug candidates, respectively.
Collaborate with the Toxicology Department to establish cellular models of drug metabolism, induction, and predictive toxicologic mechanisms.
Skills and Abilities
Experience conducting in vitro and ex vivo biotransformation assays utilizing LC-MS/MS techniques for quantitation and structure elucidation.
Experience, skills, and abilities must include knowledge of contemporary bioanalytical techniques, including wet chemistry separations, liquid chromatography, and mass spectrometric analysis, instrument operation, and data processing. Knowledge of enzyme kinetics desirable.
Ability to incorporate software in the maintenance of databases to collate and catalog records and inventory.
Independence in the laboratory and data work-up phases of research.
A working knowledge and awareness of general laboratory procedures.
Good written and oral communication skills.
Ability to adhere to all safety regulations and procedures.
Education and Experience
PhD in Organic Chemistry, Biochemistry, Analytical Chemistry or related discipline with 2-5 years direct industrial biotransformation experience following Post Doctoral training
M.Sc. in a discipline previously described with 5-7 years direct industrial biotransformation experience
Working command of in vitro kinetic analysis and utilization of contemporary mathematical models to effectively analyze, interpret and/or model drug clearance, predicted half life, and drug-drug interactions
Ability to perform mass spectrometry data collection, analysis and interpretation experience via LC-MS/MS
Candidates possessing a command of Pharmacokinetic modeling, analysis, interpretation and simulation desirable
Physical Activity and Working Conditions
Work is normally performed in a typical interior office work or laboratory environment
Work environment involves exposure to potentially dangerous materials and situations that require following extensive safety precautions and may include use of protective equipment
The noise level is usually moderate
This position will frequently be involved with radiant/electrical energy, solvents, grease, oil, irritants, acids, bases, and other hazardous chemicals, electro-mechanical hazards, flammable materials and bio-hazards. Due to exposure to hazardous biological material (which may include HIV positive specimens), immunization to Hepatitis B and/or other diseases may be a requirement.
Salary will be commensurate with experience and responsibilities. Benefits include health and dental coverage, short- and long-term disability, paid time off, paid parental leave, 401K participation with company match, and more!
Inotiv is an Equal Opportunity Employer. It is our policy to provide a fair and equal employment opportunity to all persons, regardless of age, race, color, religion, gender, gender identity, sexual orientation, physical or mental disability, national origin, veteran status, or any other basis prohibited by law. This policy governs all aspects of employment, including selection, job assignment, compensation, discipline, termination and access to benefits and training.
#LI-JM1
#LI-Onsite
*This position could be offered at different levels for candidates who qualify with a combination of advanced levels of education and/or years of experience. The salary range will adjust along with the level of the role to match the person's relevant experience and/or education level.
Inotiv is a growing contemporary drug discovery and development company where we “Play to Win” in an industry rich with opportunity. Together, we face challenges and together we win in the delivery of world-class drug discovery and development solutions that impact the health and well-being of people all over the world. There's an opportunity for everyone at all phases of a career, each individual's unique skill set has an impact on the work we conduct. If you have the talent and desire to impact the quality of people's lives, we have the career opportunities to make it happen. Join us in embracing research and science to impact the health and well-being of people all over the world.
Salary will be commensurate with experience and responsibilities. Benefits include health and dental coverage, short- and long-term disability, paid time off, paid parental leave, 401K, and more!
Inotiv is an Equal Opportunity Employer. It is our policy to provide a fair and equal employment opportunity to all persons, regardless of age, race, color, religion, sex, gender, gender identity, gender expression, sexual orientation, genetic information, disability, national origin, veteran status, or any other basis prohibited by law. This policy governs all aspects of employment, including selection, job assignment, compensation, discipline, termination and access to benefits and training.
$75k-100k yearly est. Auto-Apply 22d ago
Junior Toxicologist
Sensient Technologies 4.9
Principal research scientist job in Saint Louis, MO
At Sensient Technologies, we are experts in the science, art and innovation of color and flavor. We are market savvy and visionary. We are problem solvers. And we will be better with you.
Are you a recent graduate or early-career scientist looking to turn your toxicology education into hands-on experience? This is a great opportunity to learn on the job, build practical regulatory skills, and work with ingredients used in everyday consumer and food-related products.
You don't need years of experience, just curiosity, organization, and a willingness to learn. This role is ideal if you're self-motivated, enjoy working with data and documentation, and want to grow into a career in toxicology, regulatory affairs, or product safety.
This opportunity is 100% office based in St Louis, MO.
What you'll do:
Conduct and support safety assessments of raw materials and ingredients, including actives, impurities, carryovers, and formulations.
Assist with toxicological evaluations such as hazard identification, exposure assessment, risk characterization, and derivation of safety/risk values.
Perform literature searches and data reviews to evaluate toxicological information in line with regulatory guidance.
Support the preparation and maintenance of regulatory and safety documentation, including dossiers, safety summaries, and responses to regulatory or customer inquiries.
Maintain toxicology databases and documentation, collaborate with cross-functional teams, and stay up to date on global chemical and food regulatory requirements.
What you'll bring:
Bachelor's or Master's degree in Toxicology, Pharmacology, Chemistry, Biochemistry, or a related scientific discipline.
0-2 years of relevant experience in toxicology, regulatory affairs, product stewardship, or related areas (including academic projects or internships).
Foundational knowledge of toxicology and toxicokinetics (ADME) and exposure-based risk assessment across key endpoints (e.g., acute and repeated dose toxicity, genotoxicity, carcinogenicity, reproductive and developmental toxicity).
Basic understanding of food ingredient and chemical regulations, such as EU REACH, CLP, Cosmetics Regulation, Food Contact Materials, or similar global frameworks.
Strong organizational and project management skills, with the ability to manage data, work with regulatory databases, and communicate effectively across teams.
What you'll get:
Opportunity to collaborate with your colleagues, onsite 5 days per week
An excellent salary, benefit offering and development opportunities
A thorough and effective training experience during onboarding and beyond
About Sensient:
Sensient Technologies Corporation is a leading global manufacturer and marketer of colors, flavors, and extracts. Sensient employs advanced technologies at facilities around the world to develop specialty food and beverage systems, cosmetic and pharmaceutical systems, specialty colors, and other specialty and fine chemicals. The Company's customers include major international manufacturers representing most of the world's best-known brands.
About Sensient Colors:
Sensient Colors is a leading developer, producer, and supplier of natural and synthetic color systems for customers around the globe. The Company's high-performance products play a vital role in the manufacture of foods and beverages, cosmetic and pharmaceutical colors and coatings, and colors for agricultural uses, household cleaners and paper products.
SPONSORSHIP: Due to our inability to offer visa sponsorship, we can only consider candidates who are authorized to work in (country) without the need for employment visa sponsorship.
RELOCATION: We are unable to offer relocation assistance. The successful candidate will be expected to work at (location) and must reside in area or be willing to commute.
THIRD PARTY AGENCY: Any unsolicited submissions received from recruitment agencies will be considered property of Sensient Technologies, and we will not be liable for any fees or obligations related to those submissions.
Sensient is an Equal Opportunity Employer, headquartered in Milwaukee, Wisconsin, USA.
#LI-MM1
#LI-onsite
$66k-94k yearly est. Auto-Apply 4d ago
Senior Beverage Scientist - Missouri ***Relocation Available to $140,000
Intermedia Group
Principal research scientist job in Bridgeton, MO
OPEN JOB: Senior Beverage Scientist SALARY: $110,000 to $140,000 INDUSTRY: Food & Beverages IDEAL CANDIDATE
The ideal candidate will have 5+ years in beverage application and development with a variety of products such as coffee, seltzers, teas, powder bases etc.
POSITION SUMMARY:
The Senior Scientist position, within Flavors R&D team, will leverage scientific training and industrial experience to develop and scale-up new flavor products and systems for the food and beverage market. This position is expected to tackle projects with significant technical challenges, ensuring diligence in the development, scale-up, and commercialization of innovative products that deliver on business goals.
The position requires a strong ability to work cross-functionally to set goals and timetables, drive innovation, and support commercialization efforts. Additionally, this individual will support both local and global strategies and business initiatives while providing technical expertise to internal and external customers.
ESSENTIAL FUNCTIONS:
Lead and champion a culture of safety across all activities.
Drive product development, innovation, and novel applications in beverage.
Lead the conceptualization, development, and commercialization of new beverage products and technologies.
Optimize and validate the functional performance and sensory properties of various beverages.
Support the commercial team by translating unmet consumer needs into actionable science and technology strategies.
Support internal initiatives including, but not limited to: cost reduction initiatives, production efficiencies, and quality improvements.
Provide technical leadership to address complex challenges, simplifying issues by focusing on critical priorities.
Serve as a technical expert, solving broader business issues through science and technology strategies.
Develop and execute experiments to create technical data supporting the business's commercial strategy.
Design and conduct product testing, including sensory analysis and analytical testing, as well as review and analyze resulting data.
Stay updated on emerging technologies and developments in beverage, fostering strong relationships with customers, research institutions, and industry organizations.
Represent the organization in customer meetings, presenting technologies and solutions effectively.
Collaborate with Marketing, Sales, Operations, Quality, Regulatory, and Senior Management to achieve cross-functional business objectives.
Provide high-level technical support to customers, sales teams, and internal departments on beverage issues.
Deliver written and oral reports on project status, experimental results, and technical recommendations.
Ensure the integrity of the R&D laboratory through accurate record-keeping, test design, and adherence to sanitary practices.
Support and mentor other scientists within the R&D organization.
QUALIFICATIONS:
Bachelor's Degree in Food Science or a related scientific field with 10+ years of relevant work experience, or a Master's degree with 5+ years of experience.
At least 5 years of hands-on experience in the formulation and scale-up of a wide variety of beverages including, but not limited to, dairy based and dairy alternative beverages, carbonated beverages, fortified beverages, fruit drinks, energy drinks, enhanced waters, sports drinks, tea, and/or coffee beverages is required.
Experience in UHT/HTST beverage processing is preferred.
Proven track record in product formulation, specification creation, commercialization, and new technology development.
Expertise in formulation, including the use of flavors, proteins, vitamins/minerals, stabilizers, acidifiers, sweeteners, and functional ingredients in wet and dry beverage bases.
Strong understanding of functional and sensory evaluation methods.
Proficiency with computer software, including Excel, Word, and product formulation tools.
Advanced problem-solving, data analysis, and evaluation skills.
Exceptional written and verbal communication skills.
Demonstrated ability to collaborate across teams and departments, including Marketing, Quality, and Senior Leadership.
Ability to manage and prioritize multiple projects while delivering high-quality results.
Commitment to continuous learning and staying current with industry trends and innovations.
Demonstrated ability to work in and lead cross-functional teams to deliver innovative solutions and achieve commercialization milestones.
Develop new formulations in collaboration with customers, sales, & marketing
Create and document finished goods formulas for costing and production
If you are interested in pursuing this opportunity, please respond back and include the following:
Full MS WORD Resume
Required compensation
Contact information
Availability
Upon receipt, one of our managers will contact you to discuss in full
JASON DENMARK
Recruiting Manager
INTERMEDIA GROUP, INC.
EMAIL: ****************************
LINKEDIN: ****************************************
$110k-140k yearly Easy Apply 60d+ ago
TGI/UMSL Research Scientist
University of Missouri System 4.1
Principal research scientist job in Saint Louis, MO
This position is funded by the Taylor Geospatial Institute (TGI) for a duration of two years. The program is designed to strengthen the connection between TGI and its 8 academic partner institutions through research. The position will be an active participant in the TGI's strategic initiatives (Geospatial Innovation for Food Security - GIFS and Geospatial Artificial Intelligence - GeoAI).
The TGI researchScientist will be placed and employed in the UMSL Geospatial Collaborative at the University of Missouri - St. Louis, and will report directly to its Director, Dr. Reda Amer. The TGI researchscientist is expected to spend half of their time in support of TGI's strategic initiatives and related activities in close collaboration with the TGI Director of Program Management.
As a TGI researchScientist, the role involves identifying and pursuing funding opportunities, undertaking complex research projects, exploring emerging technologies, and enriching the geospatial knowledge base through scholarly publications and presentations. This focus on innovation drives advancements in geospatial technologies while also attracting external funding and fostering partnerships with academic and research organizations. These efforts open new avenues for collaboration. enhance UMSL's reputation and capabilities in geospatial science and contribute to TGI's growth as the hub for geospatial excellence in the nation.
As a TGI researchScientist, the position engages in the planning and/or execution of TGI strategic initiatives which will include identifying funding opportunities and developing proposals with the TGI consortium and UMSL. The Scientist will work with TGI's ambitious and passionate program managers and the growth and partnerships team in the pursuit of government, industry and/or philanthropy funding.
The Geospatial ResearchScientist will play a pivotal role in supporting UMSL faculty with their research projects, securing grant funding, and fostering collaborations across TGI's consortium institutions and academic departments. This position is crucial for advancing the research objectives of the UMSL Geospatial Collaborative, advancing TGI's vision and mission, and elevating its reputation within the geospatial community.
Primary Duties Include:
* Identify and secure grant funding opportunities to support geospatial research projects. Prepare and submit compelling grant proposals, working closely with faculty and collaborators to ensure alignment with funding agency priorities.
* Actively support UMSL faculty in their research endeavors and the pursuit of funded research proposals.
* Work with TGI staff on current GIFSs and GeoAI projects and events Conduct high-quality geospatial research that contributes to the field and aligns with the strategic objectives of the UMSL Geospatial Collaborative and of TGI. Publish findings in peer-reviewed journals and present at relevant conferences.
* Lead and mentor research teams and graduate students, guiding them from project inception through to execution and dissemination of results.
Position Funding Short-Term and Long-Term:
* Short Term Funding: TGI pays 100% for two-years. The TGI researchscientist will commit half their time to actively working with TGI staff and/or on TGI activities.
* Long Term Funding: Secure their salaries by applying for grants from governmental agencies, non-profit organizations, private foundations, and industry.
Qualifications
The ideal candidate will possess:
* A Ph.D. in Geospatial Science, Geoinformatics, Remote Sensing, Computer Science or a closely related field.
* Proven experience in geospatial research, including expertise in GIS, remote sensing, spatial analysis, Python, Machine Learning and AI.
* Demonstrated success in securing research grants and a track record of scholarly publications.
* Exceptional analytical and technical skills, including proficiency in geospatial software and tools.
* Excellent communication and collaboration skills, with the ability to work effectively across disciplines and with external partners.
* Strong commitment to academic and research excellence, innovation, and collaboration. Ability to thrive in a multidisciplinary research environment and contribute to the growth and success of the UMSL Geospatial Collaborative and TGI Consortium.
Specialized Areas of Interest:
We are particularly interested in candidates with expertise in one or more of the following areas:
* Geospatial Artificial Intelligence (GeoAI) - strongly preferred
* Geospatial for agriculture, food security and climate - strongly preferred
* Digital Twins and Smart Cities
* Geospatial Big Data Analytics
* Location Intelligence (LI)
* Climate Change Analysis
Sponsorship Information
Applicants must be authorized to work in the United States. The University will not sponsor applicants for this position for employment visas.
Other Information
About UMSL Geospatial Collaborative
The UMSL Geospatial Collaborative is dedicated to advancing geospatial education, research, and innovation through interdisciplinary collaboration and real-world applications. As a founding member of the Taylor Geospatial Institute (TGI) and a partner of the National Geospatial-Intelligence Agency (NGA), and a key player in the St. Louis geospatial ecosystem, UMSL Geospatial Collaborative plays a key role in shaping the future of geospatial science. We equip students and professionals with cutting-edge skills in GIS, remote sensing, and location-based technologies. Our initiatives include academic programs, hands-on training, industry partnerships, and K-12 outreach, fostering a diverse and skilled geospatial workforce. By bridging academia, industry, and community, we strive to make geospatial knowledge accessible and impactful across multiple sectors. ******************************************
About Taylor Geospatial Institute
The Taylor Geospatial Institute (TGI) aims to be a leading global geospatial institute positioned for collaboration, impact, and community building. Humanity is facing unprecedented challenges through natural disasters, climate change, and more, but there is also rapid positive change. TGI is confronting these challenges with novel solutions, and geospatial is at the center of it all. TGI sits at the right pace, at the right time, and with the right mix of resources and stakeholders to help tackle big problems. The consortium can fuel the fires of innovation and research, and our vision, mission, and values guide the community toward these goals. Together, we will spark a revolution in geospatial science and technology to solve global problems. Join TGI to make this vision become a reality. taylorgeospatial.org/tgi_mission_and_vision/
Benefit Eligibility
This position is eligible for University benefits. As part of your total compensation, the University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts for all four UM System campuses. For additional information on University benefits, please visit the Faculty & Staff Benefits website at ***********************************************
Equal Employment Opportunity
The University of Missouri is an Equal Opportunity Employer.
To request ADA accommodations, please email the Office of Human Resources at ***************.
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$37k-54k yearly est. 2d ago
Analytical R&D Scientist
Integrated Resources 4.5
Principal research scientist job in Chesterfield, MO
A Few Words About Us - Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.
This position is with my direct client
Job Description
• High throughput protein analytics laboratory needs a competent, motivated entry-level analyst.
• Proficient with wet chemistry and analytical instrumentation.
• Emphasis on proteins desired.
• Primary roles include SDS-PAGE analysis, HPLC analysis, buffer preparation and routine testing (appearance, pH, moisture, concentration by UV, colorimetric assay).
• Responsible for general laboratory and operational support, including assisting scientific staff with lab maintenance activities.
Qualifications
• Associate or BS degree in any science related discipline with 1-3 years of related experience or MS degree with 0-2 years preferred
• 1-3 years of experience in wet chemistry or analytical instrumentation
Additional Information
With Regards,
Ricky Bansal
732-429-1925
$69k-97k yearly est. 60d+ ago
Senior Analytical Scientist
Merck KGaA
Principal research scientist job in Saint Louis, MO
Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role:
In this role you will be involved with problem solving, working within project timelines, and contributing to documentation for method qualification and transfer into GMP manufacturing.
* Serve as a subject matter expert in analytical development, perform troubleshooting / provide efficient and innovative solutions, and support transfer of analytical methods to GMP QC labs.
* Utilize customer-facing skills, document experimental results, communicate results to all stakeholders, author method development and qualification documents, contribute to information for customer proposals.
* Serve as a project lead and ensure project deliverables are on quality and on time, develop multiple technical approach plans as needed to solve problems and mitigate risk, ensures process and methods are in place for efficient GMP start.
* Lead project teams, influence exemplary work in other team members, lead process improvement initiatives, scout for new technologies / emerging trends, proactively consider the impact of quality, regulatory, manufacturing, and safety requirements when planning project activities.
Who You Are:
Minimum Qualifications:
* Bachelor's Degree in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 6+ years of research experience.
OR
* Master's Degree in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 2+ years of research experience.
OR
* PhD in in Chemistry, Biochemistry, Biomedical Engineering, Chemical Engineering or other Life Science or Engineering discipline and 1+ years of research experience.
Preferred Qualifications:
* Experience with protein characterization via ELISA, SPR, Isoelectric Focusing, CE-based methods, UV-Vis, and/or chromatography (HPLC/GC/IC/UPLC/SEC/HILIC).
* Experience with advanced laboratory techniques; theory and practice to enable the development of novel approaches to solve complex process and analytical problems on fast-paced projects with changing priorities.
* Knowledge of small molecule or bio-therapeutics drug development process.
* Experience with antibody-drug conjugation.
* Knowledge in Biochemistry or Organic Chemistry.
* Experience in automation in an analytical setting and instrument maintenance and troubleshooting.
* Knowledge of Microsoft Word, Excel, and PowerPoint.
* Experience with advanced data acquisition and/or statistical software systems.
* Ability to coordinate information exchange and manage data generated by contract testing labs.
RSREMD
Pay Range for this position: $68,700/yr - $132,700 yr.
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
$68.7k-132.7k yearly 38d ago
Clinical Research Investigator (MD/DO)
DM Clinical Research
Principal research scientist job in Saint Louis, MO
Clinical Research Investigator DM Clinical Research, the largest privately-owned research management organization in the Houston area and one of the top 50 in the country, is looking for an Investigator for our sites in St. Louis, MO. This individual will conduct all clinical trials (studies) according to ICH, GCP, local regulations, study protocols, and company processes. Responsibilities
Ensures the medical well-being and safety of the participants through the safe performance and execution of the studies.
Assists in maintaining clinical oversight and quality on the studies registered on and delivers on study targets, thereby contributing to the commercial success of the site.
Reviews enrollment progress, pre-screening and screening success rates, screen failure rates, safety, and retention of participants.
Interprets protocols and IB and participates in initiatives to strategize for patient recruitment.
Carries out clinical evaluation and assessment of participants to ensure eligible participants are enrolled onto studies.
Ensures and protects the welfare and safety of participants through ethical conduct.
Fulfills and comply with all medical duties as per protocol, SOP/COP and ICH GCP and local regulations.
Exercises meticulous attention to detail in documentation and patient care.
Requirements
Medical License (MD, DO)
At least 2 years of experience as a Clinical Research Investigator.
Spanish Bilingual a plus.
$53k-79k yearly est. 60d+ ago
Principal Scientist - Biotransformation
Inotiv
Principal research scientist job in Saint Louis, MO
The PrincipalScientist of Biotransformation will assist with the identification of enzymatic pathways that metabolize drug candidates in preclinical in vitro and in vivo models, including human tissue and cellular models (e.g., P450, non P450/AO/FMO, conjugative/UGT). Working primarily with preclinical species and human tissues/organ subcellular fractions, the individual will utilize contemporary mass spectrometry techniques (LC-MS/MS) to identify and elucidate the structures of drug metabolites (small molecules, peptides, oligonucleotides). The individual will contribute to the development of in vitro-to-in vivo relationships related to drug clearance & half-life predictions. The individual will collaborate with Pharmacology and Toxicology laboratory leadership to establish Novel Approach Methodologies (NAMs) to address mechanistic inquiries and/or platform screening processes for same.
Join us in embracing research and science to impact the health and well-being of people all over the world.
Essential Duties and Responsibilities
* Design and execute laboratory studies aimed at identifying the enzymatic pathways that metabolize small molecule, peptide, and oligonucleotide therapeutics employing a contemporary approach methodology to establish the primary enzyme(s) contributing to the in vitro metabolism of a drug candidate(s).
* Design and execute laboratory studies to elucidate primary drug clearance mechanisms in vitro, employing contemporary approach methodology to establish in vitro to in vivo correlations for anticipated drug clearance towards the prediction of human half life.
* Design and collaborate with in vivo pharmacology & toxicology team members to execute ADME studies (non radiolabeled); elucidating the disposition of drug candidate molecules as it pertains to absorption, distribution, metabolism, and excretion; supplementing with in vitro protein binding, and blood distribution
* For oligonucleotide and peptide molecules, design and execute in vitro studies aimed at elucidating the exonuclease/endonuclease and peptidase(s) metabolism of drug candidates, respectively.
* Collaborate with the Toxicology Department to establish cellular models of drug metabolism, induction, and predictive toxicologic mechanisms.
Skills and Abilities
* Experience conducting in vitro and ex vivo biotransformation assays utilizing LC-MS/MS techniques for quantitation and structure elucidation.
* Experience, skills, and abilities must include knowledge of contemporary bioanalytical techniques, including wet chemistry separations, liquid chromatography, and mass spectrometric analysis, instrument operation, and data processing. Knowledge of enzyme kinetics desirable.
* Ability to incorporate software in the maintenance of databases to collate and catalog records and inventory.
* Independence in the laboratory and data work-up phases of research.
* A working knowledge and awareness of general laboratory procedures.
* Good written and oral communication skills.
* Ability to adhere to all safety regulations and procedures.
Education and Experience
* PhD in Organic Chemistry, Biochemistry, Analytical Chemistry or related discipline with 2-5 years direct industrial biotransformation experience following Post Doctoral training
* M.Sc. in a discipline previously described with 5-7 years direct industrial biotransformation experience
* Working command of in vitro kinetic analysis and utilization of contemporary mathematical models to effectively analyze, interpret and/or model drug clearance, predicted half life, and drug-drug interactions
* Ability to perform mass spectrometry data collection, analysis and interpretation experience via LC-MS/MS
* Candidates possessing a command of Pharmacokinetic modeling, analysis, interpretation and simulation desirable
Physical Activity and Working Conditions
* Work is normally performed in a typical interior office work or laboratory environment
* Work environment involves exposure to potentially dangerous materials and situations that require following extensive safety precautions and may include use of protective equipment
* The noise level is usually moderate
* This position will frequently be involved with radiant/electrical energy, solvents, grease, oil, irritants, acids, bases, and other hazardous chemicals, electro-mechanical hazards, flammable materials and bio-hazards. Due to exposure to hazardous biological material (which may include HIV positive specimens), immunization to Hepatitis B and/or other diseases may be a requirement.
Salary will be commensurate with experience and responsibilities. Benefits include health and dental coverage, short- and long-term disability, paid time off, paid parental leave, 401K participation with company match, and more!
Inotiv is an Equal Opportunity Employer. It is our policy to provide a fair and equal employment opportunity to all persons, regardless of age, race, color, religion, gender, gender identity, sexual orientation, physical or mental disability, national origin, veteran status, or any other basis prohibited by law. This policy governs all aspects of employment, including selection, job assignment, compensation, discipline, termination and access to benefits and training.
#LI-JM1
#LI-Onsite
* This position could be offered at different levels for candidates who qualify with a combination of advanced levels of education and/or years of experience. The salary range will adjust along with the level of the role to match the person's relevant experience and/or education level.
Inotiv is a growing contemporary drug discovery and development company where we "Play to Win" in an industry rich with opportunity. Together, we face challenges and together we win in the delivery of world-class drug discovery and development solutions that impact the health and well-being of people all over the world. There's an opportunity for everyone at all phases of a career, each individual's unique skill set has an impact on the work we conduct. If you have the talent and desire to impact the quality of people's lives, we have the career opportunities to make it happen. Join us in embracing research and science to impact the health and well-being of people all over the world.
Salary will be commensurate with experience and responsibilities. Benefits include health and dental coverage, short- and long-term disability, paid time off, paid parental leave, 401K, and more!
Inotiv is an Equal Opportunity Employer. It is our policy to provide a fair and equal employment opportunity to all persons, regardless of age, race, color, religion, sex, gender, gender identity, gender expression, sexual orientation, genetic information, disability, national origin, veteran status, or any other basis prohibited by law. This policy governs all aspects of employment, including selection, job assignment, compensation, discipline, termination and access to benefits and training.
$63k-92k yearly est. Auto-Apply 28d ago
Crop Genome Editing Scientist II
Bayer Crop Science 4.5
Principal research scientist job in Chesterfield, MO
At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where 'Health for all Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice.
Crop Genome Editing Scientist II
Position Overview:
As a Genome Editing Scientist II, you will spearhead research projects aimed at developing advanced delivery systems for genome editing components in crop plants. Your role will involve collaborating across diverse teams to develop and implement research proposals, evaluating new delivery technologies, and staying current with scientific literature to incorporate emerging technologies. You will design and execute experiments to test novel approaches for introducing molecular cargo into plant cells, apply knowledge of plant development and reproductive biology, and develop protocols to enhance efficiency across diverse germplasm. Your work will also involve evaluating and optimizing methods to bypass traditional limitations in plant transformation systems, collaborating with molecular tool developers, and presenting findings to internal stakeholders and at scientific conferences.
YOUR TASKS AND RESPONSIBILITIES:
Lead, design, and conduct research projects focused on developing advanced delivery systems for genome editing components in crop plants;
Collaborate across diverse teams to develop and implement outcome-driven research proposals;
Evaluate and benchmark new delivery technologies against existing platforms;
Stay current with scientific literature to incorporate emerging technologies;
Design and execute experiments to test novel approaches for introducing molecular cargo into plant cells;
Apply knowledge of plant development and reproductive biology to identify optimal intervention points;
Develop protocols that enhance efficiency across diverse germplasm;
Evaluate and optimize methods that bypass traditional limitations in plant transformation systems;
Collaborate with molecular tool developers to integrate delivery systems with cutting-edge technologies;
Analyze experimental data to guide iterative improvement;
Present findings to internal stakeholders and at scientific conferences.
WHO YOU ARE:
Bayer seeks an incumbent who possesses the following:
Required Qualifications:
PhD in plant biology, developmental biology, plant physiology, or related field;
3+ years of post-PhD research experience in plant science;
Strong knowledge of plant development, reproductive biology, and tissue differentiation;
Experience with plant modification methods and molecular biology techniques;
Demonstrated expertise in microscopy and cellular manipulation techniques;
Track record of innovative thinking and successful technology development;
Evidence of scientific leadership through publications and/or patents;
Outstanding written and verbal communication abilities;
Track record of innovative thinking and solving big problems;
Ability to work collaboratively in a team environment.
Preferred Qualifications:
Experience with reproductive biology, embryo development, or specialized tissue culture;
Experience with corn;
Knowledge of plant regeneration systems and developmental pathways;
Familiarity with advanced molecular delivery approaches;
Background in cell-specific targeting or tissue-specific expression;
Understanding of plant germplasm diversity challenges;
Understanding of bioinformatic tools for analyzing editing outcomes;
Background in synthetic biology or nucleic acid chemistry.
Employees can expect to be paid a salary between $99,699.20 - $149,548.80 Additional compensation may include a bonus or incentive compensation (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.. This salary range is merely an estimate and may vary based on an applicant's location, market data/ranges, an applicant's skills and prior relevant experience, certain degrees and certifications, and other relevant factors.
This posting will be available for application until at least January 5, 2026.
#LI-US
YOUR APPLICATION
Bayer offers a wide variety of competitive compensation and benefits programs. If you meet the requirements of this unique opportunity, and want to impact our mission Science for a better life, we encourage you to apply now. Be part of something bigger. Be you. Be Bayer.
To all recruitment agencies: Bayer does not accept unsolicited third party resumes.
Bayer is an Equal Opportunity Employer/Disabled/Veterans
Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below.
Bayer is an E-Verify Employer.
Location:
United States : Missouri : Chesterfield
Division:
Crop Science
Reference Code:
858368
Contact Us
Email:
hrop_*************
$99.7k-149.5k yearly Easy Apply 39d ago
Field Research Scientist - North America
Elemental Enzymes
Principal research scientist job in Saint Louis, MO
Field ResearchScientist
Join a passionate, innovative team driving the future of sustainable agriculture! We're looking for a skilled soil scientist with hands-on experience in crop input field testing (5+ years) and a strong academic foundation-BS or MS in Soil Science preferred. In this role, you'll apply cutting-edge crop production and research techniques to help shape breakthrough products that improve plant health and enrich the planet.
Job Description:
Under the direction of the Field Research Lead, the successful candidate will execute a North American-based field research program through a combination of Contract Research Organizations, academic testing agreements, and hands-on field trials. This program focuses on plant nutrition enhancement, fertilizer efficiency, and supports other platforms such as plant pathology and crop stress mitigation for agronomic crops (small grains, legumes, cotton, and oil crops).
Supports internal teams and external partners to fulfill testing objectives in an efficient and timely manner including in-season data collection, plot assessments, UAV flights and data analysis, trial summary analysis, and reporting.
Supports the development of field trial protocols and standard operating procedures globally.
Manage trial logistics including seed treatment, fertilizer impregnation, treatment preparation, and equipment organization and maintenance.
Generate and present actionable field trial data summaries that inform product development and strategic decisions.
Ability to write scientific assessments of field data in support of state and federal product registration needs.
Learn, utilize, maintain proficiency, and support internal software platforms such as MS-Excel, ARM, drone flight and data tools, and others for the analysis, organization, reporting and cataloging of field data.
Additional responsibilities may be added at the discretion of management.
Required Experience:
Bachelor's degree in Soil Science (strongly preferred) or a related field such as Plant Pathology or Agronomy, plus at least 5 years of crop input field testing experience.
OR Master's degree in Soil Science (strongly preferred) or a related field, plus at least 3 years of experience in an agronomic or plant research environment.
Proven ability to independently manage multiple, geographically dispersed field trials.
Strong knowledge of crop production, framing practices, and some farming equipment operation.
Working knowledge of crop related statistical analyses.
Excellent understanding of trail design.
Demonstrated ability to balance and prioritize tasks.
Excellent organizational and record keeping skills.
Proficiency in the use of ARM, ARM-ST, Microsoft Office, especially Power Point and Excel.
Other:
Ability to get and hold:
FAA Remote Pilot Certificate (Part 107) licenses
State Pesticide Applicators Licenses
CCA strongly encouraged.
Ability and willingness to work extended hours and extended work trips during the peak planting, growing and harvest seasons is required.
Estimated 25% overnight travel: growing season trial visits, harvest needs, industry conferences, and commercial meetings may be required. Major travel requirements between Memorial Day and Labor Day. Weekend travel or work only in exceptional circumstances.
Energetic and self-motivated individual able to work in a distributed team environment with an eagerness to develop, learn and adopt new methods.
Physical Demands:
Extending: Extend self in a direction to complete a task.
Stationary Position: Remaining in one position for sustained periods of time.
Moving: Moving to accomplish tasks, particularly for long distances or moving from one work site to another.
Fine Motor Skills: Using fingers for tasks such as typing, picking, or pinching, rather than full hand movements.
Transporting: Moving objects from a lower to a higher position or moving objects horizontally from position-to-position. Objects can be up to 45 pounds in weight.
Manual Handling: Gripping, grasping, or applying pressure to objects using fingers and palms.
Repetitive motion: Engaging in recurring movements of the wrists, hands, or fingers, such as typing or assembling components.
Medium Work: Exerting up to 50 pounds of force occasionally, up to 30 pounds of force frequently, and/or up to 10 pounds of force constantly to move objects.
Physical Requirements:
Sensory Touch: Assessing the size, shape, texture, or temperature of objects by touch, particularly with fingertips.
Communicating: Expressing or exchanging ideas by spoken word, including providing detailed or critical instructions clearly, quickly, and accurately. Perceiving sound details at normal speaking levels. Alternative methods of communication can be utilized as necessary.
Environmental Exposure: This position is involved working in outdoor field environment where the employee may be exposed to various environmental conditions, including:
Outdoor Exposure: The worker will regularly work outdoors and may be subject to various weather conditions, including sun, wind, rain, and temperature extremes. There is limited protection from the elements during these activities.
Heat Exposure: The worker may be exposed to high temperatures, sometimes exceeding 100 °F for extending periods (more than one hour). This may be further influenced by other factors such as humidity and wind.
Job Location: Remote with time commitments to Headquarters, St. Louis, MO, United States
Position Type: Full-Time/Regular/Salary/Exempt
Salary: Competitive base range
Benefits: 401K with match, Healthcare, Dental, Vision, Life Insurance, HSA/FSA options, Dependent Care Account, Employee Assistance Program, Short-Term Disability, Long-Term Disability, Pet Insurance, Accident Insurance, Critical Illness Insurance, Hospital Indemnity Insurance, Long-Term Incentive Plan
About Elemental Enzymes
Elemental Enzymes was founded upon the simple belief that we must do everything we can to improve agricultural performance in a way that not only enables plants to flourish but enriches and renews the planet with eco-friendly and sustainable agricultural solutions. From products that enable effective enzyme, peptide and protein inputs to foliar treatments that hold the promise to renew entire industries, our focus to make a positive difference in the world through people - like you and me. Success is a byproduct of responsible production. That's why Elemental Enzymes works to bring cross-disciplinary scientists and processes together to create novel solutions to practical problems with a shared goal of helping both the plant and the planet.
Please fill out the application and attach a cover letter and CV/Résumé. References required upon request.
$42k-63k yearly est. 31d ago
Bench Scientist
Artech Information System 4.8
Principal research scientist job in Saint Louis, MO
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
High throughput protein analytics laboratory needs a competent, motivated entry-level analyst. Proficient with wet chemistry and analytical instrumentation. Emphasis on proteins desired. Primary roles include SDS-PAGE analysis, HPLC analysis, buffer preparation and routine testing (appearance, pH, moisture, concentration by UV, colorimetric assay). Responsible for general laboratory and operational support, including assisting scientific staff with lab maintenance activities.
Qualifications
Min BS Degree required
Additional Information
Best Regards,
Anuj Mehta
************
$57k-82k yearly est. 60d+ ago
Bench Scientist I
Mindlance 4.6
Principal research scientist job in Saint Louis, MO
Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at *************************
Duration: 18+ Month (With possible extension)
Location: St. Louis, MO
Minimum education experience required: Associates degree with 5 years of experience/ Bachelor's degree with 1 year of experience
Experience required: 0-3 years
Top 3 critical skills: Buffer preparation; Concentration by UV; pH
Job Description: Proficient with wet chemistry and analytical instrumentation (emphasis on proteins desired). Primary roles include SDS-PAGE analysis, buffer preparation and routine testing (appearance, pH, moisture, concentration by UV, colorimetric assay, etc.) for a high throughput Protein Analytics laboratory. Responsible for general laboratory and operational support, including assisting scientific staff with lab maintenance activities. Proficiency with Excel spreadsheets is required. Basic laboratory skills including use of balances and adjustable pipets, ability to work with Excel spreadsheets, and attention to detail are required
Qualifications
Minimum education experience required: Associates degree with 5 years of experience/ Bachelor's degree with 1 year of experience
Experience required: 0-3 years
Top 3 critical skills: Buffer preparation; Concentration by UV; pH
Additional Information
All your information will be kept confidential according to EEO guidelines.
$52k-74k yearly est. 60d+ ago
Tech Transfer Scientist/Engineer.
Global Channel Management
Principal research scientist job in Chesterfield, MO
Global Channel Management is a technology company that specializes in various types of recruiting and staff augmentation. Our account managers and recruiters have over a decade of experience in various verticals. GCM understands the challenges companies face when it comes to the skills and experience needed to fill the void of the day to day function. Organizations need to reduce training and labor costs but at same requiring the best "talent " for the job.
Job Description
This position is responsible for taking an active role in the
technical transfer of processes into the clinical manufacturing facility
and/or transfer of processes out to commercial manufacturing or a CMO.
Some of the detailed responsibilities will include:
- Lead meetings to facilitate the Tech Transfer process.
- Identify, communicate, track, and hold team members accountable for project deliverables.
- Evaluate lab-scale processes and define the scaled up process for the clinical production facility.
- Interface with development scientists and propose options to resolve process fitting issues.
- Capture and convey process details by preparing detailed Process Flow Diagrams
- Provide raw material forecasts for clinical campaigns.
- Write master batch records and solution records for clinical production.
- Monitor the progression of the clinical campaigns and provide data summaries to stakeholders
- Write campaign summaries and provide information for regulatory filings
- Participate in and/or initiate continuous improvement projects.
- Provide support for engineering studi
Qualifications
Qualifications
Background in a biological or engineering discipline (Biotechnology, Biochemistry, Biochemical Engineering, or equivalent).
Experience with project management tools and methodologies is desirable.
What is the minimum education experience required?:
Backg
Additional Information
$53hr
12 MONTHS
$53 hourly 4h ago
Data Science - Senior
Verite Group, Inc. 4.1
Principal research scientist job in Saint Louis, MO
* Requires an active TS/SCI Security Clearance What Impact You'll Have: We are looking for a Senior Data Scientist, with experience processing and analyzing large datasets, who will use their technical knowledge, experience, and customer-centric focus to create and deliver world-class analytic processes, scripting solutions, and data modeling content. This is a mission-driven opportunity to support the DoD and Intelligence Community. The Data Scientist will coordinate with our clients to understand questions and issues involving the client's datasets, then determine the best method and approach to create data-driven solutions within program guidelines. This position will be relied upon as a Subject Matter Expert (SME), and be expected to lead/assist in the development of automated processes, architect data science solutions, automated workflows, conduct analysis, use available tools to analyze data, remain adaptable to mission requirements, and identify patterns to help solve some of the complex problems that face the DoD and Intelligence Community (IC).
What You'll Be Owning:
* Work with large structured / unstructured data in a modeling and analytical environment to define and create streamline processes in the evaluation of unique datasets and solve challenging intelligence issues
* Lead and participate in the design of solutions and refinement of pre-existing processes
* Work with Customer Stakeholders, Program Managers, and Product Owners to translate road map features into components/tasks, estimate timelines, identify resources, suggest solutions, and recognize possible risks
* Use exploratory data analysis techniques to identify meaningful relationships, patterns, or trends from complex data
* Combine applied mathematics, programming skills, analytical techniques, and data to provide impactful insights for decision makers
* Research and implement optimization models, strategies, and methods to inform data management activities and analysis
* Apply big data analytic tools to large, diverse sets of data to deliver impactful insights and assessments
* Conduct peer reviews to improve quality of workflows, procedures, and methodologies
* Help build high-performing teams; mentor team members providing development opportunities to increase their technical skills and knowledge
What You Must Have:
* Active TS/SCI Clearance with ability to obtain a CI Poly 10+ years of relevant experience. (A combination of years of experience & professional certifications/trainings can be used in lieu of years of experience)
* Experience supporting IC operations Possess expert level knowledge to manipulate and analyze structured/ unstructured data
* Demonstrated experience in data mining and developing/maintaining/manipulating databases
* Demonstrated experience in identifying potential systems enhancements, new capabilities, concept demonstrators, and capability business cases
* Demonstrated experience using GOTS data processing and analytics capabilities to modernize analytic methodologies
* Demonstrated experience using COTS statistical software (Map Large, Tableau, MatLab) for advanced statistical analysis of operational tools and data visualization which enables large datasets to be interrogated and allows for patterns, relationships, and anticipatory behavioral likelihoods that may not be apparent using traditional single discipline means Knowledge of advanced analytic methodologies, and experience in implementing and executing those methodologies to enable customer satisfaction
* Demonstrated experience in directing activities of highly skilled technical and analytical teams responsible for developing solutions to highly complex analytical/intelligence problems
* Experienced in conducting multi-INT and technology specific research to support mission operations
* Possess effective communications skills; capable of providing highly detailed information in an easy-to-understand format
What Would Be Nice to Have:
* Possess Master's degree in Data Science or related technical field Experience developing and working with Artificial Intelligence and Machine Learning (AI/ML)
* Demonstrated experience of advanced programming techniques, using one or more of the following: HTML 5/Javascript, ArcObjects, Python, Model Builder, Oracle, SQL, GIScience, GeospatiavAnalysis, Statistics, ArcGIS Desktop, ArcGIS Server, Arc SDE, ArcIMS.
* Experience using NET, Python, C++, and/or JAVA programming for web interface development and geodatabase development.
* Experience building and maintaining databases of GEOINT, SIGINT, or OSINT data related to the area of interest needs.
* Data Visualization Experience which may include Matrix Analytics, Network Analytics, Graphing Data that assist the analytical workforce in generating common operational pictures depicting fused intelligence and information to support informal assessments and finished products
$84k-115k yearly est. 12d ago
Analytical Scientist
Actalent
Principal research scientist job in Maryland Heights, MO
We are seeking a dedicated Quality Control Scientist to join our team supporting both contract development and manufacturing organization operations and a new compounded pharmaceutical manufacturing line. This role emphasizes method development, validation, and technical problem-solving for small-molecule products and compounded formulations. The ideal candidate will possess strong analytical expertise and extensive experience in pharmaceutical quality systems.
PAY - $48 - $72
Responsibilities
* Design, develop, and validate analytical methods for compounded pharmaceutical products and small-molecule drug substances and products.
* Support method transfer activities between internal teams and external partners.
* Develop methods for impurity profiling, degradation studies, and stability testing.
* Provide technical insights for complex analytical challenges, including root cause analysis for deviations and out-of-specification results.
* Collaborate with Quality Assurance on investigations and corrective actions.
* Ensure analytical methods and documentation meet regulatory requirements for FDA submissions and CMC packages.
* Maintain compliance with cGMP and industry standards for laboratory operations.
* Participate in CDMO development projects, contributing analytical expertise to formulation and process development.
* Work at the bench as needed to execute laboratory studies and support project timelines.
* Identify and implement process improvements within QC workflows to enhance efficiency and compliance.
* Support audit readiness and contribute to maintaining a robust quality culture.
Essential Skills
* Minimum 10-15 years of experience in analytical method development and validation within a pharmaceutical environment.
* Strong knowledge of HPLC, GC, MS, dissolution, and other analytical techniques.
* Diverse experience with various drug product types, APIs, intermediates, small-molecule, and compounded pharmaceuticals.
* Understanding of regulatory guidelines (FDA, ICH) and cGMP standards.
* Excellent technical writing skills.
Additional Skills & Qualifications
* Bachelor's or advanced degree in Chemistry or a related field.
* Familiarity with compounding operations and small-molecule development preferred.
* Ability to mentor and coach others, with potential to lead teams.
* Empathetic leadership skills and an understanding of diverse employee backgrounds.
* Integrity, transparency, and a collaborative approach to decision-making.
Work Environment
The team currently includes three other chemists in the lab. The position offers a flexible day shift from Monday to Friday, along with two weeks of PTO and holiday pay. This is an excellent opportunity to join a rapidly growing business, with the chance to establish and shape processes in a dynamic environment equipped with new GC's and HPLC's, using the latest Open Lab Software with Agilent.
Job Type & Location
This is a Contract to Hire position based out of Maryland Heights, MO.
Pay and Benefits
The pay range for this position is $48.08 - $72.11/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully onsite position in Maryland Heights,MO.
Application Deadline
This position is anticipated to close on Jan 19, 2026.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
$48.1-72.1 hourly 14d ago
Associate Scientist: CMC Process Development
Wugen
Principal research scientist job in Saint Louis, MO
Join a fast-paced startup based in St. Louis with the opportunity to help drive process development activities of novel therapies for treating rare diseases. The associate scientist role is part of the CMC department, and will focus on executing experiments in flow cytometry.
Primary Responsibilities
* Works under general supervision, to conduct and monitor laboratory experiments in molecular biology and/or flow cytometry utilizing established and published procedures.
* Assumes responsibility for the accuracy, quality, and timeliness of experimental results. Analyzes and summarizes experimental results and reviews conclusions with supervisor. Consistently records results according to established formats.
* May communicate results of experiments in the form of reports and presentations.
* Performs work according to established internal safety guidelines and procedures, and as specified by appropriate external regulatory agencies (e.g., OSHA).
* Contribute to daily laboratory operations such as ordering and stocking. Formulate simple and complex reagents. Use all equipment properly and perform maintenance if needed.
Preferred Qualifications
* Degree in biology or related field. 3+ years' experience with a BS, 1+ years with an MS.
* Mammalian tissue culture experience and ability to use aseptic technique.
* Direct experience and basic understanding of fluorescent principles.
* Experience with either nucleic acid amplification or flow cytometry. Other immunostaining also considered.
* Nucleic acid extraction or protein handling experience. Experience handling clinical specimens a plus.
* Familiar with Microsoft Office suite of programs, especially Excel and programs used for data analysis.
APPLY NOW
Email: Brunda Tumala
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$39k-60k yearly est. Easy Apply 60d+ ago
Geodetic Scientist
Core4Ce Careers
Principal research scientist job in Saint Louis, MO
We are seeking a candidate who is highly knowledgeable in Geodesy with deep expertise in science and theories governing the Earth's geometry, orientation, motion, and physical fields. The ideal candidate will understand how the size and shape of the Earth are measured and modeled, how the planet moves through space, and how its gravitational and magnetic fields behave and evolve over time. This role supports advanced research, analysis, and mission applications that rely on precise Earth modeling and geophysical insight.
Key Responsibilities:
Apply advanced geodetic theory to characterize and model the Earth's size, shape, and physical properties.
Analyze Earth orientation parameters, rotational dynamics, and orbital motion as they apply to mission and system requirements.
Interpret and model gravitational and magnetic potential fields and their temporal variations.
Support the development, refinement, and validation of geodetic reference frames, Earth system models, and geophysical datasets.
Provide expert consultation to government stakeholders, mission planners, and technical teams on geodesy-related impacts to systems, sensors, and analytic workflows.
Prepare technical reports, briefings, and recommendations for both technical and non-technical audiences.
*This position is designed to be flexible, with responsibilities evolving to meet business needs and enable individual growth.
Required Qualifications:
Degree in geological sciences, geodesy, geophysics, physics, or quantum physics.
TS/SCI (will need to obtain a CI Poly)
Strong knowledge of geodesy, Earth system science, or related geophysics disciplines. Understanding of Earth shape, gravity models, magnetic field theories, and Earth orientation/rotation dynamics.
Experience applying geodetic or geophysical principles to scientific, analytic, or operational problems leveraging interpolation methods, kriging and least square colocation.
Ability to interpret complex geophysical datasets and communicate findings clearly.
Experience with geodetic reference frames, satellite geodesy, GNSS, or gravity/magnetic modeling.
Familiarity with IC or DoD mission areas that rely on precise Earth modeling.
Degree in geological sciences, geodesy, geophysics, physics, or quantum physics.
Experience with Python, MATLAB, GIS software (ArcGIS Pro/GIS applications).
5 years of relevant experience and a BA/BS degree. OR a MA/MS degree and 3 years of relevant experience; OR a PhD degree.
Why Work for Us?
Core4ce is a team of innovators, self-starters, and critical thinkers-driven by a shared mission to strengthen national security and advance warfighting outcomes.
We offer:
401(k) with 100% company match on the first 6% deferred, with immediate vesting
Comprehensive medical, dental, and vision coverage-employee portion paid 100% by Core4ce
Unlimited access to training and certifications, with no pre-set cap on eligible professional development
Tuition assistance for job-related degrees and courses
Paid parental leave, PTO that grows with tenure, and generous holiday schedules
Got a big idea? At Core4ce,
The Forge
gives every employee the chance to propose bold innovations and help bring them to life with internal backing.
Join us to build a career that matters-supported by a company that invests in you.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy), national origin, disability, veteran status, age, genetic information, or other legally protected status.
$46k-69k yearly est. 41d ago
Learn more about principal research scientist jobs
How much does a principal research scientist earn in Saint Louis, MO?
The average principal research scientist in Saint Louis, MO earns between $55,000 and $117,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.
Average principal research scientist salary in Saint Louis, MO