A biotechnology firm in San Jose is seeking a motivated Sr. or PrincipalScientist to join the Histopathology Lab. This role involves designing and executing histopathology workflows to evaluate oncology targets. You'll need extensive hands-on experience in histology and immunohistochemistry, with responsibilities including assay development and collaboration with teams. The company offers comprehensive benefits including medical insurance, 401(k), and paid time off.
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$120k-185k yearly est. 3d ago
Lead Foundational AI Scientist for Logs & Time Series
Cisco Systems 4.8
Principal research scientist job in San Jose, CA
A leading technology company is seeking a Principal Applied AI Scientist to define AI and foundation models' strategic vision, lead groundbreaking research initiatives, and mentor technical talent. Candidates should have a PhD in Computer Science, 8+ years of industry experience, and proficiency in Python and deep learning frameworks. This role emphasizes collaboration, innovation, and the application of advanced AI for real-time data processing. Competitive salary and comprehensive benefits offered in a flexible work environment.
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$140k-178k yearly est. 5d ago
ML Research Scientist
Strativ Group
Principal research scientist job in San Jose, CA
About the Role
Our client - one of the most ambitious AI research labs is hiring ML ResearchScientists, Cheminformatics! With offices based in California and New York, this team is unlocking groundbreaking therapies for patients with severe diseases. They work at the intersection of machine learning, physics, and computational chemistry to advance the development of small molecule drug discovery. Backed by top investors and founded by ex-Google/Stanford Scientists, they are scaling their Cheminformatics team.
Why Join?
World-Class Research - Work alongside AI pioneers from the most elite institutions and industry labs - Google/Meta/OpenAI/Stanford/Harvard/MIT
Massive Compute - Unparalleled access to cutting-edge infrastructure
Research - this is about making fundamental advances in deep learning, representation learning, and generative models. Developing SOTA models within active drug programs, taking the lead on model validation, deployment to drive the discovery of new medicines
Real-World Impact - Your work won't sit in a paper; it will be deployed in groundbreaking AI systems
Who We're Looking For:
We're seeking top-tier ML researchscientists, Cheminformatics with a strong track record of applying machine learning methods to advance small molecule drug discovery.
Your Responsibilities:
Cheminformatics expert skilled in molecular data and tools like RDKit and OpenEye.
Experienced in experimental drug discovery assays and CADD workflows, from docking to ADME prediction.
Proficient data scientist and applied ML engineer, fluent in Python, scikit-learn, and PyTorch.
What We're Looking For:
PhD in Cheminformatics, Computational Chemistry, Computer Science
Expert in advanced modelling techniques, including GNNs, multitask modelling, active learning, and Bayesian optimisation.
Experienced in large-scale data management, SQL, data pipelines, and robust approaches to molecule featurisation and model validation.
Locations:
San Francisco, New York City
Package:
Salary up to $350,000K + benefits and equity options.
Ready to shape the future of AI? Apply now and join a team redefining intelligence.
$95k-160k yearly est. 4d ago
Research Scientist - Diffusion
Kadence
Principal research scientist job in San Jose, CA
AI ResearchScientist - Diffusion Models & Quantum Algorithms
About the Company
Our client is an are an early-stage, well-funded deep-tech company building next-generation quantum computing hardware tightly coupled with advanced AI algorithms. Our team works across the full stack-from quantum hardware and error correction through to quantum and probabilistic algorithms.
They are currently expanding our presence in San Francisco, where a new research lab is being established to focus on AI and quantum algorithms, working in close daily collaboration with an existing core research team in the Midwest.
The company is under a year into its current form, scaling rapidly, and led by founders with strong academic and industry research backgrounds.
The Opportunity
We are hiring an AI ResearchScientist to lead foundational research at the intersection of:
Diffusion / probabilistic generative models, and
Quantum computing and quantum algorithms
What You'll Work On
1. Accelerating diffusion models
Design and implement methods to accelerate training and inference for diffusion and probabilistic generative models
Explore mappings from classical acceleration techniques (e.g. ODE / solver-based methods such as DPM-Solver) to quantum algorithms
Build and benchmark “drop-in” quantum-inspired or quantum-native replacements for components of diffusion pipelines
2. Noise, probability, and quantum effects
Investigate how quantum noise can be treated as a feature rather than solely a limitation
Study noise distributions in diffusion processes and how quantum noise differs from classical noise
Identify application domains where quantum sampling or noise properties may provide unique advantages
3. Inference & systems optimization
Develop inference optimization strategies that generalize across GPUs, TPUs, and emerging hardware
Build and maintain robust research codebases for diffusion models
Evaluate approaches with clear quantitative metrics (speed, quality, cost, scaling behavior)
4. Cross-stack collaboration
Work closely with quantum hardware and algorithms researchers across sites
Translate between AI/diffusion requirements and quantum hardware constraints
Help define abstractions and interfaces that expose new hardware capabilities to AI practitioners
What We're Looking For
We value depth of thinking, research ownership, and technical range over any single credential.
Required experience
Deep experience in diffusion / probabilistic generative models
or
quantum algorithms, with strong interest in the other
Proven research ability, demonstrated through publications, preprints, technical reports, or equivalent output
Strong coding skills (e.g. Python; PyTorch, JAX, or TensorFlow) and comfort with modern ML stacks
Ability to independently:
Comfort moving between theory and practice (math, algorithms, and production-quality research code)
Experience working with modern accelerators (GPUs required; TPUs or other stacks a plus)
Nice to have
Hands-on work with diffusion models (image, video, text, or scientific domains)
Experience with ODE/SDE-based samplers or inference acceleration techniques
Background in quantum circuits, quantum error models, or NISQ vs. fault-tolerant regimes
Experience on inference, optimization, or efficiency teams for large models
Prior collaboration with quantum ML or quantum information research groups
Location & Working Model
San Francisco, CA (hybrid; 3-4 days onsite)
In-person days are coordinated to maximize collaboration
Frequent interaction with the core research team in the Midwest via daily syncs and periodic visits
$95k-160k yearly est. 1d ago
Research Scientist
Goliath Partners
Principal research scientist job in San Jose, CA
We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring a ResearchScientist on a hybrid basis.
They have seen $300M in a recent fund raise.
Skills targeted:
PhD in Physics/ Quantum Physics/ Theory/ Statistics/ Mathematics/ Computational Science or similarly related field.
2+ YoE working with AI Agents.
Good exposure to LLMs.
Ideally a background in Audio focused research. Alternatively Search, would also be highly advantageous.
TC package of $1-1,5M with sizeable base salary & equity package.
If that looks of interest, apply & Goliath will be in touch!
$95k-160k yearly est. 1d ago
Senior LLM Research Scientist
Acceler8 Talent
Principal research scientist job in San Jose, CA
We're hiring a Senior LLM ResearchScientist to join a well-funded, frontier physical AI startup building systems with general physical ability - AI that can experiment, engineer, and manufacture in the real world.
The team is pushing LLMs far beyond chat interfaces and into autonomous, tool-using agents that drive real engineering workflows. These systems operate inside a 20,000 sq ft physical intelligence factory and support a $42M federally funded program, representing one of the most advanced real-world deployments of reasoning-first AI today.
This is a small, world-class algorithmic team working from first principles to build long-horizon reasoning, planning, and alignment frameworks for AI systems with real-world consequences.
What you'll do:
Build advanced planning, decomposition, and structured tool-use frameworks for high-agency LLM agents
Lead SFT, RLHF/DPO, verifier-guided RL, and routing strategies to unlock major capability gains
Design schemas, tool-call policies, safety constraints, and failure-recovery mechanisms for autonomous agents
Drive integration with agent systems to evaluate LLM behavior in real engineering and manufacturing loops
Work closely with researchers, systems engineers, and infrastructure teams in a fast-moving research environment
What we're looking for:
Senior or Principal-level experience in LLM research, reasoning models, agent systems, or structured tool use
Strong background in SFT, RLHF, DPO, or verifier-driven RL, with demonstrated impact on model capabilities
Deep understanding of long-horizon planning, policy constraints, and behavioral evaluation
Comfortable operating across ML research, systems engineering, and real-world toolchains
Thrives in high-ownership, first-principles, frontier research environments
Location: Redwood City, San Francisco (Onsite preferred)
$118k-188k yearly est. 2d ago
Senior Scientist
Jiangsu Surun Talent Development Group Co., Ltd.
Principal research scientist job in San Jose, CA
🌍 Long-Term Recruitment: Senior Scientist / Postdoctoral Researcher / Lecturer / Professor
We are recruiting outstanding PhDs in science and engineering to participate in collaborative projects with universities, research institutes, and enterprises in China. Candidates may work part-time online or full-time in China.
Our partners include leading universities, research institutes, and listed companies, with strong advantages in international collaboration and innovation. We continue to introduce outstanding overseas PhDs and are committed to building a world-class research team.
Research Directions
We sincerely welcome applicants with interdisciplinary backgrounds. Research fields include, but are not limited to:
1. Core Research Fields (Strategic Domains)
Next-Generation Information Technology
High-End Equipment & Intelligent Manufacturing
Advanced Materials & Functional Materials
Biomedicine & Biopharmaceuticals
Energy & Sustainability (New Energy, Energy Efficiency, Environmental Protection)
New Energy Vehicles (NEVs) & Power Systems
AgriTech & Bio-Breeding
Digital Creativity & Future Computing Technologies
Interdisciplinary Hard Technology
2. Urgent Hiring Areas (Chemistry, Materials & Related Sciences)
Chemical Engineering: Research on chemical processes, industrial chemistry, process optimization, reaction safety, and large-scale chemical production.
Polymer Science & Engineering: Design, synthesis, modification, and applications of advanced polymers, including high-performance structural and functional polymeric materials.
Advanced Functional & Sustainable Materials: Development of smart, eco-friendly, high-performance materials for energy, environment, medical, and industrial applications.
Catalysis & Reaction Engineering: Homogeneous/heterogeneous catalysis, photocatalysis, electrocatalysis, catalytic reactor design, and advanced reaction engineering.
Materials for Electronics & Biomedicine: Semiconductor materials, soft electronics, biomaterials, nanomaterials, multifunctional coatings, and advanced biomedical materials.
Energy Materials: Battery materials (Li/Na/Zn/Solid-state), hydrogen energy systems, fuel cells, photovoltaic materials, and energy storage systems.
3. Newly Added Urgent Hiring Fields
Optics & Photonics: Optical materials, photonic devices, laser technology, fiber optics, imaging systems, and optical instrumentation for scientific and industrial applications.
Astronomy & Space Science Materials: Instrumentation for telescopes, aerospace materials, detector technologies, optical coatings, space-environment-resistant materials, and simulation research related to astrophysical environments.
PI Thin-Film Technology (Polyimide Films): High-performance PI film synthesis, processing, coating technologies, flexible electronics applications, insulation films, and ultra-high-temperature polymer research.
Chemical Metallurgy & Extractive Engineering: Metal extraction, separation and purification, metallurgical chemical reactions, mineral processing, corrosion science, and advanced metallurgy for battery/semiconductor materials.
4. Additional Priority Talent Areas
We are also urgently seeking experienced scientists and engineers (3+ years) with expertise in the following specialized domains:
OCA Optical Adhesives (Optically Clear Adhesives)
Silicon Photonics & Optoelectronic Coupling
LED Epitaxy & Semiconductor Optoelectronics
Water Treatment Membrane Technologies - especially Hollow Fiber Membranes
TMR Magnetic Sensor Chips & Spintronics
Polyurethane Materials & Foaming Technologies
Engineering Plastics & High-Performance Modified Polymers
Ceramic Dielectric Materials - including Ceramic Filters & RF Antenna Materials
Power Semiconductor Devices - including GaN and SiC Materials
5. Emerging & Priority Fields
Biomedicine: Cell Therapy, Molecular Immunology, Biopharmaceuticals, Drug Development
Artificial Intelligence: Machine Learning, Computer Vision, Intelligent Manufacturing
Sustainability: Carbon Neutrality, Environmental Engineering, Green Resources
6. Key Responsibilities
Conduct independent and/or collaborative scientific research
Publish in high-quality peer-reviewed journals
Apply for national/international research funding
Supervise graduate students or junior researchers (if applicable)
Collaborate with domestic and international teams for research-to-industry translation
7. Candidate Requirements
PhD in Chemistry, Materials, Engineering, Physics, Optics, Data/AI, or related fields
3+ years of postdoctoral or professional research experience preferred
Strong academic record (publications, patents, or projects)
Independent research capability and willingness to collaborate
Open to all nationalities
Compensation & Benefits
Annual Salary: USD 100,000 - 350,000+ (based on qualifications)
Research Startup Funding: Up to USD 400,000
Housing & Settlement Support: Up to USD 400,000 (talent apartments, rental subsidy, or purchase assistance)
Additional Benefits:
Furnished talent housing or temporary accommodation
Visa, residence permit, household registration support
Healthcare, children's education assistance
Comprehensive onboarding and long-term service
Career Development Pathways
Academic Track: Lecturer → Professor
Research Track: Assistant Researcher → Senior Scientist
Opportunities to establish independent research groups
Support for international conferences and collaborations
About Us
We are a multinational academic and technology exchange company promoting global collaboration in research and innovation. Partnering with leading universities, institutes, and enterprises, we actively attract global PhDs to form internationally competitive research teams.
Through our global platform, we foster cross-border knowledge exchange, technology transfer, and talent development, driving forward scientific advancement and innovation.
Application
📩 Please send your application to:
***********************
***************************
Application Email Title: “Application + Research Direction + Name”
Required Materials:
Resume (education background, research experience, publications, representative works)
$118k-188k yearly est. 2d ago
Scientist/Senior Scientist (Organ Perfusion)
Commonwealth Sciences, Inc.
Principal research scientist job in San Jose, CA
located in San Francisco, CA
Responsibilities of the Scientist/Sr. Scientist (Organ Perfusion):
Will lead the design and operation of systems that integrate perfusion, physiology, sensing, actuation, and closed-loop control.
Perform identification, characterization, and mitigation of long-horizon failure modes.
Apply your expertise in organ perfusion, preservation, and viability assessment.
Define measurements, interpret dynamics, and drive improvements in system-level function.
Will collaborate with scientists and engineers across the company on a variety of methods inspired by first principles of biology, physics, and chemistry.
Ability to comfortably execute familiar assay protocols as well as identifying and implementing unfamiliar protocols to diagnose damage.
Propose adjustments to cryopreservation protocol to optimize the health of organs.
Requirements of the Scientist/Sr. Scientist (Organ Perfusion):
MS or PhD with 2+ years relevant experience working with physiological systems.
Must have experience with perfusion, ECMO, organ support, or normothermic preservation.
Experience with real-time instrumentation and sensing in biological environments.
$118k-188k yearly est. 4d ago
Applied Scientist
Octopyd
Principal research scientist job in San Jose, CA
One of our partner company, are not just building AI-they're redefining what's possible at the nexus of physics, programming, and machine learning. As an Applied Scientist on their team, you'll tackle real-world scientific and coding challenges-developing novel reinforcement-learning algorithms and physics-informed models that accelerate breakthroughs in logic, coding, and semiconductor design. If you thrive on pushing the envelope of research and translating cutting-edge ideas into production-grade systems, this is your stage.
What you'll do
Prototype and validate new algorithms. Design, implement, and empirically evaluate novel RL, supervised, and unsupervised methods-especially those that leverage physics priors or logical constraints.
Bridge research and production. Collaborate closely with ML Engineers and infrastructure teams to integrate experimental models into scalable pipelines, ensuring reproducibility, observability, and sub-second performance.
Build robust experimentation platforms. Develop and maintain data-processing pipelines, training orchestration, and evaluation frameworks to accelerate iteration on large-scale experiments.
Analyze and iterate. Dive deep into large datasets-experimental logs, simulation outputs, and user interaction traces-to diagnose model behavior, surface failure modes, and drive evidence-based improvements.
Publish and present. Document findings in technical reports, contribute to open-source projects, and present work internally (and externally, when appropriate) to help shape the broader AI research community.
What You Bring
PhD or Master's in Computer Science, Applied Mathematics, Physics, Electrical Engineering, or a closely related field, with a strong focus on machine learning, reinforcement learning, or scientific computing.
Hands-on experience developing and evaluating ML/RL algorithms-ideally demonstrated via publications, open-source contributions, or applied research projects.
Proficiency in Python and deep-learning frameworks (PyTorch or TensorFlow), with solid coding practices for collaborative research.
Excellent communication skills: able to distill complex technical ideas into clear narratives for both technical and non-technical audiences.
Bonus Points
(Not required, but great to have):
Prior work on physics-informed neural networks, scientific simulations, or logic-based learning.
Demonstrated expertise in reinforcement learning for combinatorial optimization, theorem proving, or code generation.
Background in semiconductor design flows, EDA tools, or hardware-in-the-loop experimentation.
What it's like here
We're a rapidly growing, VC-backed startup where “raw talent and collaborative spirit over ego” isn't just a motto-it's how we work every day. You'll be surrounded by teammates who have built companies from zero to IPO, led teams at Google and Amazon, and earned medals in international science Olympiads. We value relentless curiosity, humble problem-solving, and a bias toward action.
Logistics
Redwood Shores, CA (U.S.) and Toronto, ON (Canada)
Schedule: four days in our beautiful office, one day remote
Visa Sponsorship: We welcome H-1B transfers and other employment-based visas
$104k-165k yearly est. 2d ago
Research Scientist in Generative AI Graduate (Intelligent Creation) - 2026 Start (PhD)
Tiktok 4.4
Principal research scientist job in San Jose, CA
The Intelligent Creation Team is the AI, special effects, and audio-video creation technology team, responsible for the core technology and business development. It covers a variety of technical fields, including deep learning, computer vision, graphics, speech, shooting and editing, special effects, client and server engineering, and provides cutting-edge content understanding, content creation, interactive experience, and consumption capabilities and industry solutions to other business lines within the company and external partners in various forms.
We are looking for talented individuals to join our team in 2026. As a graduate, you will get unparalleled opportunities for you to kickstart your career, pursue bold ideas and explore limitless growth opportunities. Co-create a future driven by your inspiration with TikTok.
Successful candidates must be able to commit to an onboarding date by end of year 2026.
Please state your availability and graduation date clearly in your resume.
PhD:
Applications will be reviewed on a rolling basis - we encourage you to apply early.
Responsibilities
* Conduct cutting-edge research and development in computer vision and machine learning, especially in the areas of generative AI (e.g. image, video, or 3d generation).
* Transfer advanced technologies to TikTok and other products;
* Explore new products with artificial intelligence technology at its core.Minimum Qualifications:
* Final year Ph.D or recent Ph.D graduates in Computer Science or related engineering field.
* Excellent collaboration and interpersonal skills
* Highly competent in algorithms and programming; Strong coding skills in Python/C++.
Preferred Qualifications:
* Multimodal generation, such as text-to-image/video/3D generation and editing, and other related multimodal experiences
* Image generation, video generation, 3D generation;
* Diffusion model, GAN, transformer for generation tasks.
* Large-scale training, RLHF, and generative AI.
* Preferring candidates with publications in top-tier venues such as CVPR, ECCV, ICCV, NeurIPS, ICLR, SIGGRAPH or SIGGRAPH Asia, etc
$144k-224k yearly est. 60d+ ago
Research Scientist Graduate (Foundation Model-Speech-Multimodal Interactions) - 2026 Start (PhD)
Bytedance 4.6
Principal research scientist job in San Jose, CA
The Seed-Speech Team empowers interactive content and creative expression through cutting-edge speech and audio technologies. We focus on foundational model research and engineering across speech recognition, synthesis, and transformation, as well as full-duplex dialogue, real-time voice interaction, music generation, and multimodal integration. Recent innovations such as Seed-LiveInterpret (low-latency speech-to-speech translation), Seed-Realtime Voice (expressive conversational voice modeling), and Seed-Music (controlled music creation) highlight our mission to push the boundaries of natural, seamless, and creative human-AI communication. We are looking for talented individuals to join our team in 2026. As a graduate, you will get opportunities to pursue bold ideas, tackle complex challenges, and unlock limitless growth. Launch your career where inspiration is infinite at ByteDance. Successful candidates must be able to commit to an onboarding date by end of year 2026. Please state your availability and graduation date clearly in your resume. Responsibilities - Conduct cutting-edge research and development in speech/audio foundation models. - Collaborate with cross-functional teams to identify key research areas and contribute to the development of innovative speech/audio models. - Work with product development teams to integrate research findings into practical applications for ByteDance and other platforms. - Collaborate on team-driven projects to address complex challenges and enhance the overall effectiveness of the research team.
Minimum Qualifications 1. Master's or PhD in computer science, mathematics, engineering or related field 2. Experience in one or more areas of machine learning and deep learning, including but not limited to: - Full-Duplex Speech Models - Speech Language Models - Automatic Speech Recognition - Automatic Speech Translation - Speech/audio self-supervised learning and foundation models - Speaker recognition and verification - Speech emotion recognition - Multimodal foundation models - Large Language Model pretraining and finetuning Preferred Qualifications - Publications in top-tier ML/DL venues such as NeurIPS, ICLR, ICML, AAAI and speech venues such as ICASSP, ASRU, Interspeech - Deep understanding of Large Language models - Familiar with distributed computing and large scale model training - Familiar with deep learning frameworks such as Tensorflow and Pytorch. - Familiar with engineering principles and best practices. - Highly competent in algorithms and programming; Strong coding skills in C/C++ and Python. - Ability to work collaboratively in a fast-paced, multi-functional environments By submitting an application for this role, you accept and agree to our global applicant privacy policy, which may be accessed here: ********************************************
$165k-239k yearly est. 26d ago
Research Scientist / Engineer - Agents
Chipstack
Principal research scientist job in San Jose, CA
Chips are at the center of today's tech-driven world. But how we design them has not changed in decades, while their complexity and specialization have skyrocketed due to increasing performance demands from applications like AI. We want to change that.
Our team is small, technical, and fast-moving. We've built and shipped at the intersection of AI, EDA, and systems software, with deep roots at companies like Qualcomm, Nvidia, Google, Meta, and the Allen Institute for AI. We're backed by top investors including Khosla Ventures, Cerberus, and Clear Ventures, and already deployed with 10+ innovative customers-from Fortune 100s to cutting-edge AI silicon startups.
Role Overview
You'll design, engineer, and research agentic systems-software that plans, executes, uses tools, and learns. You'll bridge LLM agent research (prompting, tool use, memory architectures) with the engineering that puts these systems in production for chip design workflows.
Key Responsibilities
Agent Research & Prototyping
Architect and iterate on agentic components: memory, context engineering, tool usage, multi-agent coordination
Experiment with prompting, finetuning, and orchestration to improve agent performance
Infrastructure Development
Build scalable infrastructure for prompt iteration/testing, benchmarking, logging, and evaluation
Assist with pipelines for fine-tuning, automated evaluation, and model deployment.
Collaboration & Integration
Work directly with chip designers and ML infra engineers to embed agentic workflows into chip design pipelines
Partner with product teams to solve core agent challenges (e.g., long-horizon planning, tool integration)
Research & Metrics
Define and evaluate performance metrics for agent systems
Design goal-oriented agentic workflows to enhance task completion
You Should Have
5+ years of combined ML research and / or software engineering experience
Hands-on with LLMs: prompting, finetuning, evaluation
Strong programming skills
Solid foundations in distributed systems, data pipelines
Cloud + on-premise infra experience involving GPUs. Familiarity with Docker
Excellent communication & a bias toward collaborative problem-solving
PhD or MS in ML, CS, or related field, or equivalent research + implementation experience
Ability to build, evaluate, and iterate LLM-based applications
Nice-to-Have
Experience in fine-tuning LLMs specifically for agentic applications
Experience designing agentic systems or multi-agent workflows
Familiarity with reinforcement learning (RLHF/RL-agent contexts)
Background in integrated ML infra and agent evaluation pipelines
Interest or experience in the chip design/EDA domain
What Makes This Role Unique
Play a key role at the intersection of agent research and real-world infra, delivering autonomous workflows for chip design
Influence both the research direction and the productionization of agentic systems
Join a tight-knit founding team, directly impacting high-stakes chip-design automation tasks
Culture
Challenge status quo
: We are innovators who can challenge the status quo and push forward our vision of the world.
Strong opinions, loosely held
: We are low on ego, but high on collaboration. We are okay to be wrong and are always open to learning.
Ship fast, ship quality
: We ruthlessly prioritize what matters. We build a few things, but at lightning speed with high quality.
Proud of our craft
: Attention to detail is in our DNA. We take pride in what we build and ensure they exceed the high standards of the semiconductor industry.
$95k-160k yearly est. Auto-Apply 60d+ ago
AI Research Scientist
Insight Global
Principal research scientist job in San Jose, CA
Insight Global is seeking a team of experienced, driven AI Research Engineer to join an established health technology company sitting San Jose, CA. This is a full-time, permanent role with competitive salary, bonus, and comprehensive benefits. In this role you'll need:
Design and Run ML Experiments: Set up and analyze machine learning experiments, build strong baselines, and choose the right evaluation metrics for each task.
Stay Current with AI Research: Continuously explore new research developments and adapt cutting-edge techniques to solve real-world business problems.
Establish Evaluation Standards: Define robust evaluation methods, including offline metrics, user studies, and adversarial (red team) testing, to ensure reliable and meaningful results.
Data & Annotation Strategy: Determine data and labeling needs, create clear annotation guidelines, and manage quality assurance for labeled datasets.
Cross-Functional Collaboration: Work closely with domain experts, product managers, and engineers to refine problem definitions and align on technical and business constraints.
Build Reusable Research Tools: Develop and maintain reusable assets like datasets, modular code libraries, evaluation tools, and thorough documentation.
Optimize ML Pipelines: Partner with ML Engineers to fine-tune training and inference workflows, ensuring smooth deployment into production environments.
Contribute to the Research Community: Support academic publications and represent the company at conferences and in research forums when needed.
We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to ********************.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: ****************************************************
Skills and Requirements
- 3-5 years of experience in AI/ML research roles, ideally in applied or product-focused environments.
- Demonstrated success in delivering research-driven solutions that have been deployed in production.
- Experience collaborating in cross-functional teams across research, engineering, and product.
- Publications in top-tier AI/ML conferences (e.g., NeurIPS, ICML, ACL, CVPR) are a plus.
- Ph.D. in Computer Science, Artificial Intelligence, Machine Learning, or a related field is strongly preferred.
- Candidates with a master's degree and exceptional research or industry experience will also be considered.
$95k-160k yearly est. 60d+ ago
Research Scientist
Tinder 4.4
Principal research scientist job in Cupertino, CA
HORIZON ROBOTICS: Make human life safer and better
About Horizon Robotics
Horizon Robotics (HKEX: 9660) is a leading provider of Smart Driving solutions for passenger vehicles, empowered by our proprietary software and hardware technologies. Our solutions combine cutting-edge algorithms, purpose-built software and processing hardware, providing the core technologies for smart driving that enhance the safety and experience of drivers and passengers. Horizon Robotics is key enabler for the smart vehicle transformation and commercialization with our integrated solutions deployed at scale.
The Silicon Valley Research Lab focuses on developing novel algorithms and technologies to allow machines to learn new knowledge and skills as efficiently as humans. We are looking for someone with expertise in and enthusiasm for machine learning research, especially in Robotics, Embodied AI, Reinforcement learning (RL), etc. As a ResearchScientist in the team, you will conduct research within a specialized focus area and collaborate with internal and external world-class researchers and applied engineering teams. - Propose and formulate research problems towards solving AGI- Design, implement and evaluate algorithms, models and prototypes of AI systems- Collaborate with team members to achieve research goals- Report and present research findings internally and externally (such as in top tier academic journals and/or conferences) Here is what we'd like to see in you: - PhD degree (or close to completion)) in computer science, machine learning, robotics, or related field, with a broad knowledge of machine learning approaches and theory- Track record of coming up with and implementing new ideas in AI- Strong ability in mathematically modeling real world problems- Strong ability in implementing algorithms and systems- Hunger for learning new things- Passion in artificial general intelligence and willingness to do challenging deep research- Experience in one or more fields of artificial intelligence such as machine learning, natural language processing, computer vision, reinforcement learning, robotics, large language models, etc.- Applicants must be able to obtain work authorization in the U.S. at the time of hire and maintain ongoing work authorization during employment. This is a hybrid role with the expectation of working at least 3 days per week in our Cupertino office.The base pay range for this full-time ResearchScientist position is between $150,000 and $300,000/year plus equity incentive, depending on your experience, qualifications, education, skills and other related factors. This position is also eligible for an annual performance bonus and a competitive benefits package. Employees have day one access to medical, dental, and vision insurance, a 401(k) savings plan with company match, Paid Holidays, Sick Days and Personal Time Off. We also sponsor H-1B visas and green card petitions.Horizon Robotics is committed to be an Equal Opportunity Employer. It is our policy to provide equal employment opportunities to all qualified persons without regard to race, age, color, sex, sexual orientation, religion, national origin, disability, veteran status or marital status or any other prescribed category set forth in federal or state regulations.
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$100k-164k yearly est. Auto-Apply 60d+ ago
Research Scientist
Adobe 4.8
Principal research scientist job in San Jose, CA
Our Company Changing the world through digital experiences is what Adobe's all about. We give everyone-from emerging artists to global brands-everything they need to design and deliver exceptional digital experiences! We're passionate about empowering people to create beautiful and powerful images, videos, and apps, and transform how companies interact with customers across every screen.
We're on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We realize that new ideas can come from everywhere in the organization, and we know the next big idea could be yours!
The OpportunityAdobe Research is seeking a researchscientist who is a new or upcoming PhD graduate in Computer Science or a related field, with expertise in AI, machine learning, algorithms, and control / decision making. You will have expertise in the field, as evidenced by peer-reviewed academic publication, combined with hands-on research experience. As a researchscientist at Adobe, you will be joining a dynamic team of machine learning, deep learning, and computer systems researchers to build the future of digital experiences. You will have the opportunity to develop creative ideas suitable for academic publication, to mentor interns, and to participate in our university collaboration program. You will also work with product teams to implement those ideas as advanced features in Adobe's world-class products, thereby reaching millions of people worldwide. What you'll do
Initiate the design, development, execution, and implementation of technology research projects. Investigate the feasibility of applying scientific principles and concepts to potential inventions and products.
Plan and execute applied research.
Maintain substantial knowledge of state-of-the-art principles and theories and may contribute to scientific literature and conferences.
May participate in development of patent applications. May coordinate inter-departmental activities and research efforts.
What you'll need to succeed
PhD in Computer Science or a related technical field
Strong peer-reviewed publication track record
Solid programming skills, including Python, PyTorch, C++
Desire to do world-class publishable research and develop advanced features for Adobe's agentic research and analytics products
Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The U.S. pay range for this position is $142,700 -- $270,950 annually. Pay within this range varies by work location and may also depend on job-related knowledge, skills, and experience. Your recruiter can share more about the specific salary range for the job location during the hiring process. In California, the pay range for this position is $187,100 - $270,950
At Adobe, for sales roles starting salaries are expressed as total target compensation (TTC = base + commission), and short-term incentives are in the form of sales commission plans. Non-sales roles starting salaries are expressed as base salary and short-term incentives are in the form of the Annual Incentive Plan (AIP).
In addition, certain roles may be eligible for long-term incentives in the form of a new hire equity award.
State-Specific Notices:
California:
Fair Chance Ordinances
Adobe will consider qualified applicants with arrest or conviction records for employment in accordance with state and local laws and “fair chance” ordinances.
Colorado:
Application Window Notice
If this role is open to hiring in Colorado (as listed on the job posting), the application window will remain open until at least the date and time stated above in Pacific Time, in compliance with Colorado pay transparency regulations. If this role does not have Colorado listed as a hiring location, no specific application window applies, and the posting may close at any time based on hiring needs.
Massachusetts:
Massachusetts Legal Notice
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Adobe is proud to be an Equal Employment Opportunity employer. We do not discriminate based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Learn more.
Adobe aims to make Adobe.com accessible to any and all users. If you have a disability or special need that requires accommodation to navigate our website or complete the application process, email accommodations@adobe.com or call **************.
$187.1k-271k yearly Auto-Apply 40d ago
Senior ML Scientist, Search & Personalization
Expedia, Inc. 4.7
Principal research scientist job in San Jose, CA
A leading travel technology company in San Jose is looking for a seasoned machine learning expert to drive the research, design, and deployment of innovative solutions for search and recommendation systems. With a focus on personalization and advanced algorithms, you will collaborate with cross-functional teams to deliver user-centric AI products. The ideal candidate has over 10 years of experience in the industry, holds a Ph.D. or M.S. in a related field, and has strong proficiency in machine learning frameworks and relevant technologies.
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$153k-209k yearly est. 4d ago
Senior/Principal Scientist IHC
Integratedcooling
Principal research scientist job in San Jose, CA
About Oxford BioTherapeutics
Oxford Biotherapeutics is a clinical-stage biotechnology companyfocusing on the development of antibody therapeutics for the treatment of cancer.OBT'sOGAP-verify platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patienttumors. OGAP is used to identify novel, highlytumorspecific antigens for novel first-in-class ADC, T-cell Engager (TCE) and Chimeric Antigen Receptor (CAR-T) targets. Our lead asset, OBT076, is an Antibody Drug Conjugate (ADC) in Phase 1b clinical development. Our clinical and pre-clinical pipeline of novel biologics is balanced between internal programs, focused on ADCs and checkpoint regulators, and externally partnered programs with key innovators in oncology such as Roche, GSK, and Zymeworks.
For further information, please see *****************************
Job Description
We are seeking a motivated Sr. or PrincipalScientist to join the Histopathology Lab within the Target Validation team in San Jose, CA. The role involves independently designing, troubleshooting, and executing histopathology workflows to evaluate oncology targets, and presenting findings to teams and partners.
You will support target validation through IHC, IF, ISH, slide scanning, image analysis, and assay optimization, with a strong focus on IHC assay development, antibody screening, tissue processing (FFPE/FF), sectioning, and tissue-based assay implementation. Hands-on histology and oncology knowledge is required.
Responsibilities
Design and optimize chromogenic IHC assays using FFPE/FF samples; confirm specificity using orthogonal methods (e.g., ISH).
Lead histopathology support for cancer target programs, including materials management, hands-on lab work, mentorship of junior staff, and timeline delivery.
Present results, gather feedback, and implement next steps.
Use literature and public datasets to guide assay development and target validation.
Process tissues and cell pellets into FFPE/frozen blocks; section and stain samples using Leica Bond autostainers.
Digitize slides, analyze results, and document data in ELN and presentations.
Perform routine lab tasks: sample archiving, equipment maintenance, consumables ordering, logistics.
Support tissue database and digital data organization.
Required Qualifications and Skills
PhD + 4 years, or Master's + 6 years, or Bachelor's + 8 years or more of hands-on experience working in histology and IHC related labs, preferably supporting cancer research in an industry setting.
Extensive (>3 years) hands-on experience developing, utilizing, and interpreting immunohistochemistry assays against novel protein targets, using both single and multiplex IHC techniques primarily on FFPE sample slides.
Extensive (>3 years) hands-on experience in laboratory histology, including preparation of tissue sample into FFPE and FF blocks, preparation of cell pellet control blocks, cryostat and microtome sectioning, troubleshooting chromogenic IHC and ISH experiments, and independently identifying appropriate next steps in the development of robust, sensitive and specific tissue biomarker assays.
Experience with Leica Bond autostainers and reagents relevant to optimizing new IHC assays, typically chromogenic assays.
Experience with microscope slide scanners for brightfield and fluorescent imaging, and general experience utilizing whole-slide image analysis software such as HALO.
Collaborate effectively in a matrix-managed organization to drive advancement of early-stage projects into translational and clinical development.
Be relied upon as a technical expert in the IHC field; provide guidance to colleagues and collaborators, and mentorship to more junior lab colleagues.
Preferred Qualifications and Skills
Knowledge in cancer biology, immuno-oncology, and tumor histopathology are each a plus.
Strong track record of developing and implementing strategic initiatives to improve scientific and/or operational activities.
Relevant experience working with service providers and CROs in the histology space.
Excellent organization skills, and evidence of previous success in a growing and fast-paced work environment.
Experience regularly presenting IHC assay results in group settings.
Top candidates will be collaborative and team oriented, creative problem solvers, resilient to change, and interested in learning opportunities.
Experience with cell culture and related molecular biology assays (WB/ELISA/etc.) are additionally a plus.
Benefits Offered
Medical,dentalandvisioninsuranceforemployeeanddependents
FSA(FlexibleSpendingAccount)
STD,LTD,BasicLifeandAD&DInsurance,SupplementalLife
401(k) Plan
120hoursofPaidTimeOff
5sickdaysperyear
11holidays
EmployeeReferralBonusProgram
Annualbonusprogram
Newhirestockoptions
Equal Opportunity Statement
OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment. One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits.
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$120k-185k yearly est. 3d ago
AI Research Scientist
Strativ Group
Principal research scientist job in San Jose, CA
About the Role
Our client - a frontier AI research company at the cutting edge of molecular design is hiring AI ResearchScientists, Computational Biology, to join their growing research team.
Founded by researchers and operators from leading AI4Biology labs and top technology companies, the team is building next-generation models that move beyond benchmarks into real-world therapeutic development. Backed by world-class investors, including Thrive Capital, Dimension, OpenAI, Amplify, they are scaling their research efforts to tackle some of the most challenging problems in drug discovery.
Why Join?
Frontier Research - Work alongside world-leading researchers pushing the boundaries of AI for molecular and biological modelling
Real-World Deployment - Your research will be translated directly into active discovery programmes, not left on a shelf
Technical Depth - Tackle open-ended scientific problems involving large-scale models, complex biological data, and first-principles reasoning
Meaningful Impact - Help design technologies that have the potential to change how new therapies are created
Who We're Looking For:
We're seeking exceptional PhD Grad to Senior-Level AI ResearchScientists, Computational Biology, with a strong research background and a drive to apply cutting-edge machine learning to real therapeutic challenges.
Your Responsibilities:
Conduct original research on ML methods for molecular and biological modelling
Develop, train, and evaluate advanced deep-learning models for small molecules, antibody, proteins, or related systems
Design modelling experiments to answer ambiguous scientific questions
Collaborate closely with experimental scientists to translate model outputs into actionable insights
Support validation, iteration, and deployment of models used in live discovery workflows
What We're Looking For:
PhD in Machine Learning, Computational Biology, Bioinformatics
Strong research track record through publications, projects, or demonstrable impact
Proficiency in Python and deep-learning frameworks (e.g. PyTorch)
Experience working with molecular, chemical, or biological datasets
Familiarity with advanced modelling techniques such as representation learning, generative models, multitask learning, or uncertainty-aware methods
Locations:
San Francisco
Package:
Salary up to $350,000K + benefits and equity options
Ready to help shape the future of AI-driven drug discovery? Apply now.
$95k-160k yearly est. 2d ago
Research Scientist Graduate - (Seed Multimodal Interaction and World Model - Reinforcement Learning) - 2026 Start (PhD)
Bytedance 4.6
Principal research scientist job in San Jose, CA
About Seed Team Established in 2023, the ByteDance Seed team is dedicated to discovering new approaches to general intelligence, and pursuing the edge of intelligence. Our research spans large language models, GenMedia, AI for Science, Robotics and more. With a long-term vision and determination in AI, the ByteDance Seed team remains committed to foundational research. We aim to become a world-class AI research team that drives real technological progress and delivers societal benefits. With labs across China, Singapore, and the U.S., our team has already released industry-leading general-purpose large models and advanced multimodal capabilities, powering over 50 real-world applications - including Doubao, Coze, and Jimeng. We are looking for talented individuals to join our team in 2026. As a graduate, you will get opportunities to pursue bold ideas, tackle complex challenges, and unlock limitless growth. Launch your career where inspiration is infinite at ByteDance. Successful candidates must be able to commit to an onboarding date by end of year 2026. Please state your availability and graduation date clearly in your resume. Responsibilities: - Design and implement reinforcement learning (RL) training systems for large-scale multimodal foundation models - Develop unified modeling frameworks that integrate video, audio, and language, with a focus on visual latent reasoning - Explore RL-based approaches to bridge understanding and generation for multimodal visual reasoning - Collaborate with researchers to evaluate models on tasks involving world modeling, reasoning, and instruction-conditioned generation
Minimum Qualifications: - Individuals who are completing or have recently completed a PhD degree in Software Development, Computer Science, Computer Engineering, or a related technical discipline. - Publications in venues such as CVPR, ECCV, ICCV, NeurIPS, ICLR, ICML, or other conferences in AI and ML - Strong research background in at least one of the following: reinforcement learning, multimodal learning, video understanding, or vision-language modeling Preferred Qualifications: - Experience with reinforcement learning in multimodal or interactive environments - Familiarity with video generation or diffusion-based generative models - Experience with large-scale model training (e.g., distributed training, curriculum learning, or memory-augmented transformers) - Solid programming and engineering skills, with experience building training or evaluation pipelines for ML models
$165k-239k yearly est. 26d ago
Learn more about principal research scientist jobs
How much does a principal research scientist earn in Salinas, CA?
The average principal research scientist in Salinas, CA earns between $110,000 and $248,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.
Average principal research scientist salary in Salinas, CA