Principal research scientist jobs in Simi Valley, CA - 292 jobs
All
Principal Research Scientist
Research Scientist
Associate Scientist
Associate Principal Scientist
Postdoctoral Research Scientist
Senior Bioinformatics Scientist
Lead Scientist
Staff Scientist
Senior Scientist
Associate Principal Data Scientist
Activision Blizzard, Inc. 4.6
Principal research scientist job in Santa Monica, CA
Job Title:Associate Principal Data ScientistRequisition ID:R025545Job Description:Your Role Within Our KingdomWe are seeking an Associate Principal Data Scientist-a highly experienced and technically deep individual contributor who leads through influence, owns high-impact initiatives, and drives scientific excellence across experimentation and modeling.Responsibilities:
Lead the design and execution of large-scale data science initiatives, shaping the roadmap for experimentation and modeling across teams.
Apply advanced statistical, optimization, and machine learning techniques (e.g., time-series, regression/classification, recommendation engines, reinforcement learning, and gen AI) to drive system understanding and develop data-powered solutions across the organization.
Own design and evaluation of experimentation for optimization systems.
Provide technical direction, mentor senior data scientists, and set high standards for scientific rigor, communication, and reproducibility.
Partner cross-functionally with Product, Engineering, and Game Studios to frame ambiguous problems, scope solutions, and influence strategy.
Champion innovation by evaluating new methodologies and tools, and by raising the bar for scalable, interpretable, and actionable data science.
Skills to Create ThrillsMinimum Qualifications:
Master's degree or PhD in a quantitative field (e.g., Statistics, Mathematics, Computer Science, Economics, Engineering, Operations Research).
14+ years of industry experience (or equivalent post-graduate experience) in data science, experimentation, statistical modeling, and machine learning, including work with large-scale systems.
Proficient in Python and SQL; familiarity with big data tools (e.g., Spark, Hive) and cloud computing platforms (e.g., GCP, AWS).
Strong systems thinking-able to zoom out and define strategy while also diving deep into code and analysis.
Excellent communication and collaboration skills, with demonstrated experience partnering across Product, Engineering and Businessteams.
Demonstrated experience mentoring, influencing, and elevating the technical bar across a data science organization.
Bonus Points
Experience working with advertising data products or monetization systems.
Prior work with mobile gaming studios or player behavior modeling.
Experience in developing or maintaining experimentation platforms.
Familiarity with modern data orchestration and versioning (e.g., Airflow, dbt, MLflow).
We love hearing from anyone who is enthusiastic about changing the games industry. Not sure you meet all qualifications? Let us decide! Research shows that women, veterans, and members of other under-represented groups tend to not apply to jobs when they think they may not meet every qualification, when, in fact, they often do! We are committed to creating a diverse and inclusive environment and strongly encourage you to apply.We are committed to working with and providing reasonable assistance to individuals with physical and mental disabilities. If you are a disabled individual requiring an accommodation to apply for an open position, please email your request to accommodationrequests@activisionblizzard.com. General employment questions cannot be accepted or processed here. Thank you for your interest.We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, gender identity, age, marital status, veteran status, or disability status, among other characteristics.
Rewards
We provide a suite of benefits that promote physical, emotional and financial well-being for ‘Every World' - we've got our employees covered! Subject to eligibility requirements, the Company offers comprehensive benefits including:
Medical, dental, vision, health savings account or health reimbursement account, healthcare spending accounts, dependent care spending accounts, life and AD&D insurance, disability insurance;
401(k) with Company match, tuition reimbursement, charitable donation matching;
Paid holidays and vacation, paid sick time, floating holidays, compassion and bereavement leaves, parental leave;
Mental health & wellbeing programs, fitness programs, free and discounted games, and a variety of other voluntary benefit programs like supplemental life & disability, legal service, ID protection, rental insurance, and others;
If the Company requires that you move geographic locations for the job, then you may also be eligible for relocation assistance.
Eligibility to participate in these benefits may vary for part time and temporary full-time employees and interns with the Company. You can learn more by visiting ***************************************
In the U.S., the standard base pay range for this role is $143,060.00 - $264,846.00 Annual. These values reflect the expected base pay range of new hires across all U.S. locations. Ultimately, your specific range and offer will be based on several factors, including relevant experience, performance, and work location. Your Talent Professional can share this role's range details for your local geography during the hiring process. In addition to a competitive base pay, employees in this role may be eligible for incentive compensation. Incentive compensation is not guaranteed. While we strive to provide competitive offers to successful candidates, new hire compensation is negotiable. #J-18808-Ljbffr
$143.1k-264.8k yearly 4d ago
Looking for a job?
Let Zippia find it for you.
Lead Target Discovery Scientist - In Vitro Biology
Amgen Sa 4.8
Principal research scientist job in Thousand Oaks, CA
A leading biotech company in Thousand Oaks seeks a Senior PrincipalScientist to lead a team focused on in vitro modeling for target discovery. This role involves collaboration across therapeutic areas and implementing innovative technologies. Candidates should have a doctorate and extensive experience in a related field. Competitive compensation, flexible work models, and a comprehensive benefits package are offered.
#J-18808-Ljbffr
$125k-173k yearly est. 1d ago
Senior Applied AI Scientist
Cisco 4.8
Principal research scientist job in Santa Monica, CA
**Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment.
**Your Impact**
+ Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events.
+ Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale.
+ Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact.
+ Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes.
+ Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans.
**Minimum Qualifications:**
+ PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience.
+ Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling.
+ Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow)
+ Experience translating research ideas into production systems.
**Preferred Qualifications:**
+ Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models.
+ Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data.
+ Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights.
+ Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty.
+ Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy.
+ MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models.
+ Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications.
**Why Cisco?**
At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint.
Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere.
We are Cisco, and our power starts with you.
**Message to applicants applying to work in the U.S. and/or Canada:**
The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits.
Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process.
U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time.
U.S. employees are eligible for paid time away as described below, subject to Cisco's policies:
+ 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees
+ 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco
+ Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees
+ Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations)
+ 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next
+ Additional paid time away may be requested to deal with critical or emergency issues for family members
+ Optional 10 paid days per full calendar year to volunteer
For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies.
Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows:
+ .75% of incentive target for each 1% of revenue attainment up to 50% of quota;
+ 1.5% of incentive target for each 1% of attainment between 50% and 75%;
+ 1% of incentive target for each 1% of attainment between 75% and 100%; and
+ Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation.
For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid.
The applicable full salary ranges for this position, by specific state, are listed below:
New York City Metro Area:
$199,700.00 - $292,800.00
Non-Metro New York state & Washington state:
$174,500.00 - $260,500.00
* For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined.
** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.
Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis.
Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.
Principal research scientist job in Thousand Oaks, CA
Job: Associate Director/PrincipalScientist, CMC Analytical Chemistry
Position type: Full Time
Reports to: Director of Analytical Chemistry
Latigo Biotherapeutics (LatigoBio) is a private, early-stage biotechnology company discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes to transform the lives of patients. Latigo has a robust pipeline, is well-funded by blue chip investors, and has a highly successful management team and Board of Directors. The company was founded in 2019 and is based in Thousand Oaks, CA. We are science-based, data-driven, patient-focused, and forward-thinking.
Position Summary
Latigo is searching for an Associate Director/PrincipalScientist, CMC Analytical Chemistry. Reporting to the Director of Analytical Chemistry, the candidate will manage preclinical to clinical analytical development activities and oversee the testing and release of drug substance and drug product at contract manufacturers/service providers. The role is responsible for the development, validation and implementation of QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials at contract manufacturers.
Additional responsibilities include reference standard qualification and management, establishment of specifications, oversight of stability programs and the active management and documentation of data. The selected candidate will also work collaboratively with Quality Assurance to assess laboratory conformance with cGMPs, and with CMC Regulatory Affairs to author Module 3 sections of CTD regulatory submissions and written responses to regulatory authorities.
Primary Responsibilities
Oversee the phase-appropriate analytical activity at contract manufacturers/service providers including analytical method development, qualification and validation for drug substance and drug product.
Partner with stakeholders to develop and set specifications for raw materials, intermediates, drug substance, excipients and drug product.
Design and manage stability programs for non-GMP and cGMP drug substance and drug product batches and provide guidance for shelf-life and expiry dating.
Establish workflows and procedures for analytical and quality control activities.
Manage reference standards program, coordinate sourcing, ensure inventory, plan and execute testing and retesting activities, and manage shipments of reference standards.
Author, review and approve various analytical reports in a timely manner to support drug substance and drug product development and manufacture, and regulatory filings.
Support regulatory submissions by drafting and reviewing analytical sections of INDs, IMPDs, and NDAs, and ensure compliance with current regulatory requirements.
Sometimes represent analytical function in CMC teams and project meetings, and work closely with cross-functional teams to meet project timelines and goals.
Review/approve controlled cGMP documents, e.g., analytical methods and associated validation protocols/reports, specifications, stability protocols, change controls, LIRs, etc.
Manage/perform QC review/approval of analytical test data for IPC testing, drug substance/product batch release and stability test data.
Manage and review deviation events and OOS/OOT investigations in coordination with CMC counterparts, QA and regulatory team members.
Contribute to the building of CMC infrastructure and company culture.
Qualifications and Requirements
D. with 8+ years of experience or BS or MS in chemistry or related discipline with 10-15 years of industry experience in an analytical chemistry setting.
Good understanding and knowledge of pharmaceutical analytical methods and related issues.
Experience with analytical development of small molecules and drug product oral dosage forms from preclinical to late-stage clinical development.
Experience managing drug substance and drug product service providers in analytical matters.
Extensive knowledge of GLP and cGMP requirements, appropriate regulatory guidance and current industry practices for analytical development.
Experience in writing CMC sections for Regulatory submissions (IND experience required; NDA experience highly desirable).
Excellent computer skills (e.g., Microsoft Office, Excel, Project).
Ability to effectively manage multiple priorities and projects.
Preference given to applicants able to work (hybrid) from Thousand Oaks or San Francisco, CA offices.
$117k-184k yearly est. 4d ago
Research Scientist, Hearing Performance
Sonova
Principal research scientist job in Santa Clarita, CA
Valencia, CA - Hybrid ResearchScientist, Hearing Performance You will deliver better outcomes for cochlear implant recipients by driving feasibility research in hearing performance and remote care. You will design and conduct early-stage research studies to evaluate novel concepts. You will collaborate closely with internal R&D engineers, and with external clinics and academic researchers for study execution. In addition, you will aid in the development of research software. You will thrive in an interdisciplinary environment of researchers, clinicians, and technologists who are passionate about connecting patients to sound.
Responsibilities:
* Design and conduct feasibility studies to further improve hearing performance of cochlear implant recipients, including signal processing strategies and remote care solutions.
* Collaborate with multi-functional internal teams (software development, clinical research, marketing, quality, etc.).
* Manage collaborations with external partners (clinicians, academic researchers) to conduct research studies and validate concepts.
* Aiding in the development of research software using Python and MATLAB.
* Communicate findings through technical documentation, presentations to internal and external stakeholders, and, where appropriate, manuscripts for publication.
* Support development of intellectual property.
Travelling Requirement: 5% for visits to clinics, conferences, and external collaborators.
More about you:
* Degree in Hearing Science, Audiology, or related field; PhD preferred.
* Research background in cochlear implants, hearing aids, or related areas, plus 3+ years of industry experience in audio or medical devices.
* Strong project ownership, ability to navigate ambiguity, and excellent organizational skills.
* Effective communicator with a collaborative mindset and ability to work with diverse teams.
* Proven leadership in driving projects and external research collaborations, including developing and presenting impactful concepts.
* Broad expertise in hearing performance, signal processing, statistics, machine learning, and research software development.
* Proficient in Python, MATLAB, Microsoft Office, SQL, R, and Rust; fluent in English
A minimum of 200Mb/sec download and 10Mb/sec upload speed internet connectivity is required to support any remote/hybrid employee functionality at Sonova
Don't meet all the criteria? If you're willing to go all in and learn we'd love to hear from you!
We are looking forward to receiving your application via our online job application platform. For this position only direct applications will be considered. Sonova does not recruit via app, telegram, carrier pigeon or any other format that does not include speaking with an actual human. If you are offered a job without speaking with someone please contact Sonova Human Resources
What we offer:
* Medical, dental and vision coverage*
* Health Savings, Health Reimbursement, Flexible Spending/Dependent Care Accounts
* TeleHealth options
* 401k plan with company match*
* Company paid life/ad&d insurance
* Additional supplemental life/ad&d coverage available
* Company paid Short/Long-Term Disability coverage (STD/LTD)
* STD LTD Buy-ups available
* Accident/Hospital Indemnity coverage
* Legal/ID Theft Assistance
* PTO (or sick and vacation time), floating Diversity Day, & paid holidays*
* Paid parental bonding leave
* Employee Assistance Program (24/7 mental health support hotline, 5 company paid counseling sessions and more)
* Robust Internal Career Growth opportunities
* Tuition reimbursement
* Hearing aid discount for employees and family
* Internal social recognition platform
* Plan rules/offerings dependent upon group Company/location.
This role's pay range is between $95,200/yr - $142,800/yr. This role is also bonus eligible.
How we work:
At Sonova, we prioritize the well-being of our employees and foster an inclusive environment that promotes engagement and collaboration. Our team-customized hybrid work model empowers teams to balance individual needs with business goals, offering flexibility and individualized time management. We recognize the importance of life outside of work and strive to create a supportive and motivating workplace where innovation thrives.
Sonova is an equal opportunity employer
We team up. We grow talent. We collaborate with people of diverse backgrounds to win with the best team in the market place. We guarantee every person equal treatment in regard to employment and opportunity for employment, regardless of a candidate's ethnic or national origin, religion, sexual orientation or marital status, gender, genetic identity, age, disability or any other legally protected status.
$95.2k-142.8k yearly 19d ago
RESEARCH SCIENTIST II (CHEMICAL SCIENCES)
State of California 4.5
Principal research scientist job in Pasadena, CA
The Environmental Chemistry Laboratory (ECL), Pasadena provides DTSC with expertise in method development, quality assurance, data evaluation and analysis of environmental samples. The ECL also studies new chemicals of concern and provides DTSC management with analytical information for decision making. We are looking for a highly motivated and adaptable individual to join our team. Join us today!
As a ResearchScientist II you will have the opportunity to:
* Develop and validate standard and in-house analytical methods for DTSC special projects using sophisticated computer-interfaced equipment and Gas Chromatography (GC), High Performance Liquid Chromatography (HPLC), Inductively Coupled Plasma (ICP) and Mass Spectrometer (MS) hyphenated instruments to produce accurate, defensible and reliable data for the department to use to carry out its mandates by working independently or leading in a group
* Solve complex analytical problems such as matrix interferences, sensitivity and selectivity and optimizes instrument conditions as a part of the method development process
* Evaluate scientific literature for in-depth understanding and knowledge of the project assigned
* Use standard Environmental Protection Agency (EPA) and other authoritative methods and laboratory technical system procedures (TSPs) to analyze environmental samples submitted by DTSC core programs and external entities for enforcement, compliance, and quality assurance purposes
* Comply with the requirements in the Management System documents such as the Quality System Procedures (QSPs) and other relevant external documents to ensure defensibility of analytical results
* Prepare analytical and quality assurance/quality control (QA/QC) reports for submission
Desirable Qualifications We Look For:
* 2 years of research experience working independently on projects preferred
* 1 year of experience with mass spectrometry or other analytical techniques preferred
* Experience with standard analytical testing methods preferred
You will find additional information about the job in the Duty Statement.
Working Conditions
Visa Sponsorship: The Department of Toxic Substances Control does not provide visa sponsorship and is not an E-Verify employer.
The position is headquartered in Pasadena, CA.
Click the link below for a special message from Director Katie Butler on DTSC's culture:
DTSC - Diversity, Equity, Inclusion and Belonging (DEIB)
Minimum Requirements
You will find the Minimum Requirements in the Class Specification.
* RESEARCHSCIENTIST II (CHEMICAL SCIENCES)
Additional Documents
* Job Application Package Checklist
* Duty Statement
Position Details
Job Code #:
JC-504934
Position #(s):
************-003
Working Title:
ResearchScientist II
Classification:
RESEARCHSCIENTIST II (CHEMICAL SCIENCES)
$7,625.00 - $9,799.00
New to State candidates will be hired into the minimum salary of the classification or minimum of alternate range when applicable.
# of Positions:
1
Work Location:
Los Angeles County
Telework:
In Office
Job Type:
Permanent, Full Time
Facility:
Pasadena ECL
Department Information
This position can be located at the Environmental Chemistry Lab in Pasadena, CA.
The Department of Toxic Substances Control (DTSC) is a member of the boards, departments, and offices (BDO) within the California Environmental Protection Agency (CalEPA).
Our Mission: To protect California's people, communities, and environment from toxic substances, to enhance economic vitality by restoring contaminated land, and to compel manufacturers to make safer consumer products.
Our Vision: All of California is thriving in a healthy environment.
Our Core Values: DTSC values diversity, equity, and inclusion throughout the organization. We foster an environment where employees from a variety of backgrounds, cultures, and personal experiences are welcomed and can thrive. We believe the diversity of our employees is essential to inspiring innovative solutions. Together we further our mission to protect California's people, communities, and environment from toxic substances, to enhance economic vitality by restoring contaminated land, and to compel manufacturers to make safer consumer products. Join DTSC to improve the lives of all Californians!
DTSC Recruitment Survey:
Click here to complete the DTSC recruitment survey.
Department Website: ***********************
Application Instructions
Completed applications and all required documents must be received or postmarked by the Final Filing Date in order to be considered. Dates printed on Mobile Bar Codes, such as the Quick Response (QR) Codes available at the USPS, are not considered Postmark dates for the purpose of determining timely filing of an application.
Final Filing Date: 1/28/2026
Who May Apply
Individuals who are currently in the classification, eligible for lateral transfer, eligible for reinstatement, have list or LEAP eligibility, are in the process of obtaining list eligibility, or have SROA and/or Surplus eligibility (please attach your letter, if available). SROA and Surplus candidates are given priority; therefore, individuals with other eligibility may be considered in the event no SROA or Surplus candidates apply.
Applications will be screened and only the most qualified applicants will be selected to move forward in the selection process. Applicants must meet the Minimum Qualifications stated in the Classification Specification(s).
How To Apply
Complete Application Packages (including your Examination/Employment Application (STD 678) and applicable or required documents) must be submitted to apply for this Job Posting. Application Packages may be submitted electronically through your CalCareer Account at ********************** When submitting your application in hard copy, a completed copy of the Application Package listing must be included. If you choose to not apply electronically, a hard copy application package may be submitted through an alternative method listed below:
Address for Mailing Application Packages
You may submit your application and any applicable or required documents to:
Department of Toxic Substances Control
Pasadena ECL
Attn: Cesar Fernandez
757 S Raymond Ave., Suite 105
Pasadena, CA 91105
Address for Drop-Off Application Packages
You may drop off your application and any applicable or required documents at:
Department of Toxic Substances Control
Pasadena ECL
Cesar Fernandez
757 S Raymond Ave., Suite 105
Pasadena, CA 91105
Drop-off applications must be received, and date stamped by 5:00 PM on the final filing date.
08:00 AM - 05:00 PM
Required Application Package Documents
The following items are required to be submitted with your application. Applicants who do not submit the required items timely may not be considered for this job:
* Current version of the State Examination/Employment Application STD Form 678 (when not applying electronically), or the Electronic State Employment Application through your Applicant Account at ********************** All Experience and Education relating to the Minimum Qualifications listed on the Classification Specification should be included to demonstrate how you meet the Minimum Qualifications for the position.
* Resume is required and must be included.
Applicants requiring reasonable accommodations for the hiring interview process must request the necessary accommodations if scheduled for a hiring interview. The request should be made at the time of contact to schedule the interview. Questions regarding reasonable accommodations may be directed to the EEO contact listed on this job posting.
Benefits
Benefit information can be found on the CalHR website and the CalPERS website.
Contact Information
The Human Resources Contact is available to answer questions regarding the application process. The Hiring Unit Contact is available to answer questions regarding the position.
Department Website: ***********************
Human Resources Contact:
Talent Acquisition
**************
******************
Hiring Unit Contact:
Cesar Fernandez
**************
***************************
Please direct requests for Reasonable Accommodations to the interview scheduler at the time the interview is being scheduled. You may direct any additional questions regarding Reasonable Accommodations or Equal Employment Opportunity for this position(s) to the Department's EEO Office.
EEO Contact:
EEO Office
**************
***************
California Relay Service: ************** (TTY), ************** (Voice) TTY is a Telecommunications Device for the Deaf, and is reachable only from phones equipped with a TTY Device.
Additional Application Instructions
For experience/education to qualify during the application screening process, and to ensure that minimum qualifications can be determined, applicants should include all employment history on the Employment Application (STD 678), including detailed job descriptions, hours worked per week, and start/end dates (MM/DD/YYYY). Application packages without this information may experience delayed processing times and your eligibility for this position may be impacted.
Electronic applications submitted through your CalCareer Account are highly recommended. If you are unable to apply electronically through your CalCareer account, please mail a completed and signed STD. 678 and application package to the mailing address provided above in the "Application Instructions" section. Applications must be postmarked on or before the final filing date.
For mail-in or drop-off applications, please include JC #: 504934 and indicate the basis of your eligibility in the Examination(s) or Job Title(s) section. SROA and surplus candidates should submit a copy of their letter with their application.
Pending Budget Approval - DTSC will obtain all necessary approvals prior to extending a job offer.
Foreign Degrees
Applicants who completed their education outside the United States (with foreign degree/ transcripts) must obtain and submit verification of United States course/degree equivalency.
Foreign education credential evaluation services can be found at **********************
DO NOT include any confidential information to your application or supporting documents (i.e., Social Security Number, birthdate, marital status, medical information, examination results, method of eligibility, etc.).
Equal Opportunity Employer
The State of California is an equal opportunity employer to all, regardless of age, ancestry, color, disability (mental and physical), exercising the right to family care and medical leave, gender, gender expression, gender identity, genetic information, marital status, medical condition, military or veteran status, national origin, political affiliation, race, religious creed, sex (includes pregnancy, childbirth, breastfeeding and related medical conditions), and sexual orientation.
It is an objective of the State of California to achieve a drug-free work place. Any applicant for state employment will be expected to behave in accordance with this objective because the use of illegal drugs is inconsistent with the law of the State, the rules governing Civil Service, and the special trust placed in public servants.
$91k-151k yearly est. 10d ago
Research Scientist - Controlled 3D Generation
Stability Ai
Principal research scientist job in Los Angeles, CA
About the Role
We're seeking a ResearchScientist passionate about 3D generation, flow matching, and diffusion models. You'll help advance the frontier of controllable 3D content creation-building models that generate consistent, editable, and physically grounded 3D assets and scenes.
What You'll Do
Conduct cutting-edge research on flow-matching, diffusion, and score-based methods for 3D generation and reconstruction.
Design and implement scalable training pipelines for controllable 3D generation (meshes, Gaussians, NeRFs, voxels, implicit fields).
Develop techniques for conditioning and control (text, sketch, pose, camera, physics) and multi-view consistency.
Analyse model behaviour through ablations, visualisations, and quantitative metrics.
Collaborate with cross-disciplinary research, graphics, and infrastructure teams to translate research into production-ready systems.
Publish results at top-tier venues and work with interns.
What You Bring
PhD (or equivalent experience) in Machine Learning, Computer Vision, or Computer Graphics.
Published work on diffusion, flow-matching, or score-based generative models (2D or 3D).
Strong engineering and problem-solving abilities: experience with PyTorch, JAX, or CUDA-level optimisation.
Understanding of 3D representations (meshes, Gaussians, signed-distance fields, volumetric grids, implicit networks).
Solid grasp of geometry processing, multi-view consistency, and differentiable rendering.
Ability to scale experiments efficiently and communicate complex results clearly.
Bonus / Preferred
Experience generating coherent 3D scenes with multiple interacting objects, lighting, and spatial layout.
Familiarity with scene-level control (object placement, camera path, simulation, or text-to-scene composition).
Knowledge of video-to-3D, image-to-scene, or 4D temporal generation.
Background in physically-based rendering, simulation, or world-model architectures.
Track record of impactful publications or open-source releases.
Equal Employment Opportunity:
We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or other legally protected statuses.
$91k-152k yearly est. Auto-Apply 60d+ ago
Research Scientist, AI for the Chemical Sciences
California Institute of Technology 4.5
Principal research scientist job in Pasadena, CA
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do.
Join us and be a part of the diverse Caltech community.
Job Summary We seek a ResearchScientist with expertise at the interface of machine learning, data science, and the chemical sciences to lead the AI for the Chemical Sciences Summer Bootcamp.
This individual will design and deliver an intensive, hands-on educational program while working closely with CCE faculty and external experts.
The ResearchScientist will also support post-bootcamp research integration, enabling participants to apply AI/ML methods to active research projects across CCE.
The role is central to building sustainable computational infrastructure, curriculum, and collaborative research pathways in AI-enabled chemistry.
Essential Job Duties Lead the design, development, and delivery of a two-week immersive summer bootcamp on AI/ML for the chemical sciences.
Develop and teach lectures and hands-on computational laboratories covering data curation, molecular representations, machine learning models, deep learning, generative models, and applications in reactions, catalysis, and spectroscopy.
Coordinate with CCE faculty and invited guest lecturers to integrate domain expertise into the curriculum.
Provide year-round mentorship and technical support to bootcamp participants as they transition AI/ML skills into active research projects within CCE laboratories.
Develop and maintain computational workflows, datasets, and teaching materials for reuse and long-term integration into CCE training programs.
Support interdisciplinary research collaborations that combine experimental and computational approaches.
Contribute to the development or operation of shared automation or robotic experimentation platforms linked to AI-driven research.
Publish and disseminate methodological or applied research outcomes arising from bootcamp-enabled projects.
Assist with assessment, reporting, and continuous improvement of the bootcamp program.
Participate in outreach, workshops, and related educational activities within CCE.
Perform other related job duties as assigned.
Basic Qualifications PhD in chemistry, chemical engineering, materials science, computer science, or a closely related field.
Demonstrated expertise in machine learning and data science applied to problems in the chemical sciences.
Experience developing and implementing computational workflows for chemical data analysis or modeling.
Strong programming skills relevant to scientific computing and ML.
Experience teaching, mentoring, or training students and researchers.
Ability to work collaboratively with faculty, students, postdoctoral researchers, and administrative staff.
Strong written and oral communication skills.
High scientific rigor, creativity, and ethical standards.
Excellent organizational and time management skills, with the ability to manage multiple responsibilities.
Preferred Qualifications Experience applying ML to molecular property prediction, reactions, catalysis, or spectroscopy.
Familiarity with deep learning architectures such as graph neural networks and generative models.
Experience with ML-accelerated electronic structure methods, molecular dynamics, or spectral analysis.
Experience with automation hardware or robotic platforms for chemical experimentation.
Background in curriculum development or educational program leadership.
Familiarity with best practices in data curation, model interpretability, and responsible AI use.
Required Documents Resume
$74k-114k yearly est. 6d ago
Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute
Dev 4.2
Principal research scientist job in Los Angeles, CA
Company DescriptionJobs for Humanity is partnering with CEDARS-SINAI to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located.
Company Name: CEDARS-SINAI
Job Description
Principal Investigator, Ivan Cokic, PhD, is looking for a Postdoctoral Scientist to join the Biomedical Imaging Research Institute!
The Cedars-Sinai Biomedical Imaging Research Institute (BIRI) is an interdisciplinary research program established in 2010 to develop and apply state-of-the-art imaging technologies to today's most pressing translational research and clinical questions. Led by founding director Debiao Li, PhD, the program builds on Cedars-Sinai's clinical and research strefngths, with the ultimate goal of using novel medical imaging technology to improve the diagnosis, treatment and prevention of diseases. The BIRI team is dedicated to educating and training the next generation of the brightest imaging scientists and clinicians through our robust pre-/post-doctoral and visiting-scientist training programs. In addition, we have numerous research collaborations with leading imaging researchers. To learn more, please visit Biomedical Imaging Research Institute | Cedars-Sinai.
In this role, the Postdoctoral Scientist will be expected to work independently under the direction of Dr. Cokic and in close cooperation, as well as consultation, with other research staff. This interdisciplinary preclinical project combines advanced cardiac imaging, cardiac (electro)physiology, cardioimmunology, cardiovascular pathology, and metabolomics. In addition, assisting with investigating clinical applications of novel magnetic resonance imaging (MRI) and positron emission tomography (PET) techniques for diagnosing, phenotyping and risk-stratifying subjects with MI. As a Postdoctoral Scientist, perform routine and complex laboratory procedures throughout the training period and may develop, adapt, and implement new research techniques and protocols.
Primary Job Duties and Responsibilities:
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
May participate in publications and presentations as author or co-author.
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I.
Analyzes, interprets, summarizes and compiles data.
Operates and maintains equipment and instruments.
Department-Specific Responsibilities:
Handling of large animal (farm pigs, Yucatan minipigs, etc.) models of myocardial infarction (MI).
Writing Institutional Animal Care & Use Committee (IACUC) protocols.
Coordinating animal surgeries with team of designated research technologists.
Designing and coordinating imaging experiments on BIRI's PET/MRI scanners with team of designated research technologists.
Analysis of cardiac MRI and PET imaging data as well as histopathology and metabolomics data.
Perform advanced data and statistical analysis and will communicate scientific findings in papers and conference presentations.
Assist with database creation and management, supervision of undergraduate/graduate students.
Education:
Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required.
Experience and Skills:
Highly motivated and works independently on research projects designed by a mentor (typically the PI) within the area of specialization.
Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Highly motivated with a proven track of record of publications.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.
Knowledge of safety standards, operation, and maintenance of specialized equipment.
Working Title: Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute
Department: BMS - BioMed Imaging Res Inst
Business Entity: Cedars-Sinai Medical Center
Job Category: Academic/Research
Job Specialty: Postdoctoral
Position Type: Full-time
Shift Length: 8 hour shift
Shift Type: Day
Base Pay:$64,500.00 - $93,600.00
$64.5k-93.6k yearly 60d+ ago
Data analysis-Associate Scientist
Mindlance 4.6
Principal research scientist job in Thousand Oaks, CA
Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at *************************
Job Description
Job Summary:
Responsible for providing support to the Process Analytics group, a unit within the Digital Integration & Predictive Technologies (DIPT) organization in Process Development. The position will be based in Thousand Oaks, CA. Support will include organizing and interpreting lab data, analyzing results using statistical techniques. The responsibilities also include performing laboratory experiments including unit operations set up, calibration of various lab tools, sampling and data acquisition from primary or secondary data sources with minimal supervision.
Basic Qualifications
• Bachelor's degree
OR
• Associate's degree & 4 years of directly related experience
OR
• High school diploma / GED & 6 years of directly related experience
Preferred Qualifications
• B.Sc., in Chemical, Biochemical Engineering or Life Sciences, preferably with expertise in bio/pharmaceutical processes.
• Practical experience and interest in multivariate data analysis and predictive modeling.
• Experience working with large data sets, data mining and machine learning tools.
• Experience in Matlab or R Programming Languages and basic Microsoft tools.
• Understanding of biopharmaceuticals process, related unit operations including analytical methods and process controls.
• Strong analytical skills with the ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy
• Independent, self-motivated, organized, able to multi-task in project environments, and skilled in communication, facilitation, and collaboration.
• Team player, prepared to work in and embrace a team-based culture that relies on collaboration for effective decision-making
• Solid leadership, technical writing, and communication/presentation skills.
Qualifications
Basic Qualifications
• Bachelor's degree
OR
• Associate's degree & 4 years of directly related experience
OR
• High school diploma / GED & 6 years of directly related experience
Preferred Qualifications
• B.Sc., in Chemical, Biochemical Engineering or Life Sciences, preferably with expertise in bio/pharmaceutical processes.
• Practical experience and interest in multivariate data analysis and predictive modeling.
• Experience working with large data sets, data mining and machine learning tools.
• Experience in Matlab or R Programming Languages and basic Microsoft tools.
• Understanding of biopharmaceuticals process, related unit operations including analytical methods and process controls.
•
Strong analytical skills with the ability to collect, organize,
analyze, and disseminate significant amounts of information with
attention to detail and accuracy
• Independent, self-motivated,
organized, able to multi-task in project environments, and skilled in
communication, facilitation, and collaboration.
• Team player, prepared to work in and embrace a team-based culture that relies on collaboration for effective decision-making
• Solid leadership, technical writing, and communication/presentation skills.
Additional Information
All your information will be kept confidential according to EEO guidelines.
$84k-121k yearly est. 60d+ ago
Staff Applied Scientist, Generative AI/ML
Adobe Systems Incorporated 4.8
Principal research scientist job in Los Angeles, CA
Our Company Changing the world through digital experiences is what Adobe's all about. We give everyone-from emerging artists to global brands-everything they need to design and deliver exceptional digital experiences! We're passionate about empowering people to create beautiful and powerful images, videos, and apps, and transform how companies interact with customers across every screen.
We're on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We realize that new ideas can come from everywhere in the organization, and we know the next big idea could be yours!
The Opportunity
Adobe is seeking to add Applied Scientists in Generative AI to our world-class AI Platform team. We are specifically looking for scientists with expertise in preparing data, training, fine-tuning and adapting large foundation models across all modalities: images, video, 3D, LLMs and cross-modal setups. We welcome outstanding candidates in all related technical fields, such as Machine Learning, Deep Learning, Computer Vision, and Natural Language Processing. The related applications include image/video/3D generation, editing, and understanding, conditioned on controls stemming from large language models, or other innovative interactions tailored for creative workflows, and multimodal priors.
What You'll Do
* Conduct pioneering research and development in Generative AI for visual (image/video/3D), audio, and multi-modal outputs.
* Develop and deploy novel generative AI technologies to existing and new Adobe Products.
* Research and develop novel large-scale foundation models with deep reasoning and world-building capabilities.
* Collaborate with world-class researchers and ML engineers to bring research ideas to creative workflows used by millions.
* Publish and present your work in world-class scientific venues in CV/AI/ML/CG fields
Required Qualifications
* Ph.D. in Computer Science, CV/AI/ML/CG or related fields and 4+ years professional experience.
* Research or industry experience in training Generative AI models (pre-training and/or post-training) in at least one of the following modalities: image, video, 3D, or audio.
* Expertise in large-scale model training and optimization, including data curation, distributed training, and memory-efficient techniques.
* Experience with post-training techniques such as fine-tuning, alignment or distillation.
* Proficiency with modern deep learning frameworks (e.g., PyTorch) and experience scaling models on GPU/TPU clusters.
* Excellent communication skills and a strong great teammate
What You'll Bring
* Experience on large-scale generative model training
* Experience on synthetic data generation
* Experience of working with large-scale datasets
* Experience of working with product teams on technology transfers
#FireflyGenAI
Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The U.S. pay range for this position is $172,500 -- $306,625 annually. Pay within this range varies by work location and may also depend on job-related knowledge, skills, and experience. Your recruiter can share more about the specific salary range for the job location during the hiring process. In California, the pay range for this position is $211,800 - $306,625 In Washington, the pay range for this position is $201,000 - $291,150
At Adobe, for sales roles starting salaries are expressed as total target compensation (TTC = base + commission), and short-term incentives are in the form of sales commission plans. Non-sales roles starting salaries are expressed as base salary and short-term incentives are in the form of the Annual Incentive Plan (AIP).
In addition, certain roles may be eligible for long-term incentives in the form of a new hire equity award.
State-Specific Notices:
California:
Fair Chance Ordinances
Adobe will consider qualified applicants with arrest or conviction records for employment in accordance with state and local laws and "fair chance" ordinances.
Colorado:
Application Window Notice
There is no deadline to apply to this job posting because Adobe accepts applications for this role on an ongoing basis. The posting will remain open based on hiring needs and position availability.
Massachusetts:
Massachusetts Legal Notice
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Adobe is proud to be an Equal Employment Opportunity employer. We do not discriminate based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Learn more.
Adobe aims to make Adobe.com accessible to any and all users. If you have a disability or special need that requires accommodation to navigate our website or complete the application process, email accommodations@adobe.com or call **************.
$211.8k-306.6k yearly 60d+ ago
Associate Scientist
Us Tech Solutions 4.4
Principal research scientist job in Thousand Oaks, CA
100% Onsite Must be local in ATO **Job Details:** + Candidate will be essential on site. 1+ year of industry or 2+ academia experience in a lab setting with pipetting, sample prep & handling, HPLC chromatography, and protein sample analysis. Ideal Candidate: must have at least 1-year lab experience. BS (or equivalent) degree in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline.
+ A strong understanding of protein biochemistry and protein structure, as well as significant experience with basic laboratory skills and biophysical techniques related to protein analysis is essential. A background in protein solution manipulation (e.g. pipetting, dialysis, concentration) and HPLC analysis is expected. Experience with visible and sub-visible particle analysis and other analytical methods (e.g. capillary electrophoresis, SEC, CEX, etc.) is desirable.
**Job description** :
+ We are currently seeking a research associate for the Drug Product Technologies group in Thousand Oaks, CA.
+ A fundamental understanding of protein chemistry, formulation, and biophysical characterization is desired. The successful candidate will perform experiments related to the development of formulations for therapeutic proteins, including stability testing and analytical characterization.
+ The candidate will join a team of investigators using a variety of biochemical and biophysical techniques and will be involved in the design and execution of experiments.
+ Responsibilities will include detailed record keeping in electronic laboratory notebooks, data collection, analysis, and interpretation of experimental data and presentation.
**Basic qualifications:**
+ BS (or equivalent) degree in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline. A strong understanding of protein biochemistry and protein structure, as well as significant experience with basic laboratory skills and biophysical techniques related to protein analysis is essential.
+ The applicants must be motivated, have good problem-solving skills, and an aptitude to learn and implement new techniques/skills.
+ The candidate should be well organized and proficient in detailed record-keeping, have excellent written and oral communication skills, must be proficient in Microsoft office (word, excel, PowerPoint), and be capable of working efficiently in teams and independently.
**Advanced qualifications:**
+ MS (or equivalent) in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline. MS (or equivalent) is not required but it is preferred.
**Basic Qualifications:**
+ Masters degree OR
+ Bachelors degree and 2 years of experience OR
+ Associate's degree and 4 years of experience OR
+ High school diploma / GED and 6 years of experience
**Top 3 Must Have Skill Sets:**
+ Lab experiences, 100% onsite, looking for permanent job in industry
**Day to Day Responsibilities:**
+ Using a variety of biochemical and biophysical techniques and will be involved in the design and execution of experiments. Responsibilities will include detailed record keeping in electronic laboratory notebooks, data collection, analysis, and interpretation of experimental data and presentation.
**About US Tech Solutions:**
_US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit_ _************************ _._
_"US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran"_
$67k-101k yearly est. 7d ago
Associate Scientist Analytical Chemistry
Provivi 3.9
Principal research scientist job in Santa Monica, CA
ProviviOverview
We are amulti-national,Santa Monica-based company, founded in 2013 by Caltech scholars: Professor Frances Arnold, PedroCoelho,and Peter Meinhold.Wererethinking pest controlas innovators in pheromone technology, theengineersand creators of a family ofsafe andeffective pest control solutions formajor damaging insects. We are hiring thevery bestand brightest people toexpand our impact.
Role Description
As a member of the Provivistechnologyteam, you willhave a vital role in developingandvalidatinganalyticalmethods for detection, identification,and quantification ofsmallmolecules found in Provivisproprietarychemical andbiochemicalprocesses as well as pheromone components informulated products.Specifically, the successful candidate will develop andvalidate GC,GCMS,HPLC,and HPIC methods,as well asestablishquality controlprotocolsfor Proviviscommercial products,provide hands-on technicalassistancetomaintainanalytical equipmentin good working orders, and analyze samples supporting various projects.Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems,are essential.
ResponsibilitiesInclude
Develops,validates, and standardizes GC, HPLC, HPICanalytical methods for detection, identification,and quantification ofsmallmoleculesfound inchemical andbiochemicalprocesses, andformulated products.
Extracts,analyzesandevaluatesmaterial and products at all stages of development process under stringent quality and time requirements.
Preparesresearch reports, invention disclosures, and Standard Operating Procedures for internal and external use.
Reviewsdata for technical content and regulatory compliance.
Ensuresanalytical equipmentismaintainedin good working order; troubleshootsand performsminor repairs as needed.
Anticipatesadditionalresources,consumables, andequipment requirementsas needed to ensure that workcan be completed within the budgeted time.
Remains current withanalyticalchemistry literature and champions the implementation ofnewtechnology.
Maintainsa safe and orderly laboratory andensurescompliance with all safety policies and practices.
Qualifications& Skills Include
M.S. inanalyticalchemistry or equivalent, orbachelor'sin chemistrywith 2additionalyears of analytical lab experience
A minimum of0-2years ofbiotech and chemicalindustrial experience with hands-on experience in analytical chemistry.
A good understanding of analytical chemistry, organicchemistry,and chemical engineering principles.
Demonstrated practical ability to develop methods forisolation,characterization, and quantification ofsmallmoleculesfound inchemical and biochemicalprocesses and formulatedproducts usingconventional chromatography techniques and analytical instruments including GC,GCMS,HPLC,and NMR.
Must be skilled in operation of chromatographic data acquisition and processing software packages such as Chromeleon,ChemStation,and other software tools for data reduction and presentation.
Excellent written, reporting, and verbal communication skills
Proficient in using Microsoft Officesuiteincluding Word, Excel,and Power Point.
Ability to prioritize responsibilities and multi-taskin a fast-paced environment with changing priorities
Must behighly motivatedand capable of working independently to deliver results under tight deadlines
Able to lift 15 40 pounds.
Diversity and Equal Opportunity Employment
Proviviis an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protectedveteransstatus, or any otherlegally-protectedfactors.
$76k-115k yearly est. 5d ago
Associate Scientist - Bioinformatics
Lancesoft 4.5
Principal research scientist job in Santa Monica, CA
We are seeking a talented and highly motivated scientist with an interest in advancing Next Generation Sequencing (NGS) technologies for genomics research, to join our Bioinformatics and Sequencing group in Santa Monica. You will have the opportunity to work in a fast-paced and highly collaborative environment to support a growing R&D portfolio.
You will work at the interface of biology and technology and will support the effort on assessment and development of custom NGS needs, to assist drug target and biomarker discovery efforts.
Responsibilities
Extraction and preparation of DNA and RNA from various sources
Preparation of DNA, RNA, and ATAC-seq libraries from bulk and/or single cells for NGS sequencing
Perform quality control on samples and libraries.
Troubleshoot the experimental procedures and protocols for library preparation and sequencing under supervision
Perform Next Generation Sequencing experiments on Illumina platforms and other platforms
Perform qPCR for library quality control
Maintain updated working knowledge of Genomics technologies and develop significant experience in next-generation sequencing applications
Keep records of experiments in electronic notebook (ELN)
Deliver scientific findings effectively in group meetings and collaborative forums
Basic Qualifications
Master s Degree
OR
Bachelor s Degree and 2+ years of scientific experience
OR
AA Degree and 4+ years of scientific experience
OR
High School Degree and 5+ years of scientific experience
Preferred Qualifications
Bachelor's degree in Biological Sciences, Molecular Biology, Biochemistry, Bioengineering, Genetics, or related fields
2+ years of hands-on experience with Next Generation Sequencing (NGS) platforms, various NGS assays, and their underlying sequencing methodology
Hands-on experience with DNA and RNA extraction from various sources
Ability to learn new techniques in a fast-paced environment
Demonstrated ability to solve scientific and engineering problems
Excellent organizational skills and efficiency at getting tasks done
Goal oriented and looking to take on additional responsibilities
Experience working in a multi-disciplinary environment
Experience working with LIMS and electronic notebook e.G. Benchling
Excellent interpersonal, verbal, and written communication skills
An excellent work ethic, ability to work in a dynamic environment, and ability to adapt to changing priorities
$85k-133k yearly est. 14d ago
Senior Bioinformatics Scientist I
Fulgent Therapeutics 4.2
Principal research scientist job in El Monte, CA
About Us
Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform.
Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike.
Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company.
Summary of Position
As a Senior Bioinformatics Scientist, you will collaborate in cross-functional teams to design, implement and continually improve advanced computational pipelines for high-throughput analysis of multiple types of NGS data. You will work independently in refining methodologies for data analysis, processing, visualization and storage. You will also be assigned leadership roles in projects with mentor responsibility to junior members of the team. You will strive to maximize efficiency, quality, reliability and customer usability and satisfaction.
Key Job Elements
Research and Development
Investigate and refine available algorithms, methods and data sources.
Work independently to define, prioritize and complete objectives to meet company goals.
Make recommendations for pipeline component improvements, or new pipelines.
Write SOPs for new or updated pipeline components, or new pipelines.
Write specifications for implementation by software developers.
Oversee pipeline development and integration.
Production and Customer Support
Investigate and resolve analysis and pipeline production issues.
Review client projects for compatibility with current pipelines, make recommendations and implement customizations as needed.
Oversee sequencing service projects, ensuring timely processing, quality results and client satisfaction.
Support software and LIMS developers in automation efforts.
Perform specialized analyses as needed for specific projects.
Keep up-to-date with current best practices and emerging methods.
Treat data with a high level of integrity and ethics.
Data Maintenance
Investigate available annotation and reference data sources.
Validate and deploy/update selected data sources.
Write reports detailing validation/update methodology and results.
Write SOPs for updating existing or new data sources.
Validation
Develop appropriate procedures for testing and validation of new or updated pipelines or pipeline components.
Document and maintain data used for testing and validation.
Write validation reports detailing validation methodology and results.
Qualifications
Knowledge/Experience
Ph.D. degree from an accredited institution in Bioinformatics, Biostatistics or related field.
5+ years of experience in a related scientific discipline (Bioinformatics preferred).
Demonstrated mastery of Fulgent specific methods and processes.
Experience analyzing multiple types of next-generation sequencing (NGS) data
Expertise with statistics for big data analysis and multiomics data integration.
Expert level hands-on skills in bioinformatics databases and tools.
Expert level in relevant programming languages, preferably Scala, Java, Python, and Bash.
Must enjoy working in a multi-disciplinary and collaborative environment.
Ability to troubleshoot both individually and as part of a team.
Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner.
Experience in team software development and integration projects is a plus.
Supervisor Responsibilities
None
Reports To
Director, Biointegration
Environment
Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term “qualified individual with a disability” means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position.
For California residents, please see the link below to access our CCPA Privacy Notice.
CCPA Privacy Notice for California Residents
*******************************
Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question - that choose to submit a resume or client information to our career page or to any employee of Fulgent - will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.
Principal research scientist job in Thousand Oaks, CA
Job: Associate Director/PrincipalScientist, CMC Analytical Chemistry
Position type: Full Time
Reports to: Director of Analytical Chemistry
Organization Overview
Latigo Biotherapeutics (LatigoBio) is a private, early-stage biotechnology company discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes to transform the lives of patients. Latigo has a robust pipeline, is well-funded by blue chip investors, and has a highly successful management team and Board of Directors. The company was founded in 2019 and is based in Thousand Oaks, CA. We are science-based, data-driven, patient-focused, and forward-thinking.
Position Summary
Latigo is searching for an Associate Director/PrincipalScientist, CMC Analytical Chemistry. Reporting to the Director of Analytical Chemistry, the candidate will manage preclinical to clinical analytical development activities and oversee the testing and release of drug substance and drug product at contract manufacturers/service providers. The role is responsible for the development, validation and implementation of QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials at contract manufacturers.
Additional responsibilities include reference standard qualification and management, establishment of specifications, oversight of stability programs and the active management and documentation of data. The selected candidate will also work collaboratively with Quality Assurance to assess laboratory conformance with cGMPs, and with CMC Regulatory Affairs to author Module 3 sections of CTD regulatory submissions and written responses to regulatory authorities.
Primary Responsibilities
Oversee the phase-appropriate analytical activity at contract manufacturers/service providers including analytical method development, qualification and validation for drug substance and drug product.
Partner with stakeholders to develop and set specifications for raw materials, intermediates, drug substance, excipients and drug product.
Design and manage stability programs for non-GMP and cGMP drug substance and drug product batches and provide guidance for shelf-life and expiry dating.
Establish workflows and procedures for analytical and quality control activities.
Manage reference standards program, coordinate sourcing, ensure inventory, plan and execute testing and retesting activities, and manage shipments of reference standards.
Author, review and approve various analytical reports in a timely manner to support drug substance and drug product development and manufacture, and regulatory filings.
Support regulatory submissions by drafting and reviewing analytical sections of INDs, IMPDs, and NDAs, and ensure compliance with current regulatory requirements.
Sometimes represent analytical function in CMC teams and project meetings, and work closely with cross-functional teams to meet project timelines and goals.
Review/approve controlled cGMP documents, e.g., analytical methods and associated validation protocols/reports, specifications, stability protocols, change controls, LIRs, etc.
Manage/perform QC review/approval of analytical test data for IPC testing, drug substance/product batch release and stability test data.
Manage and review deviation events and OOS/OOT investigations in coordination with CMC counterparts, QA and regulatory team members.
Contribute to the building of CMC infrastructure and company culture.
Qualifications and Requirements
D. with 8+ years of experience or BS or MS in chemistry or related discipline with 10-15 years of industry experience in an analytical chemistry setting.
Good understanding and knowledge of pharmaceutical analytical methods and related issues.
Experience with analytical development of small molecules and drug product oral dosage forms from preclinical to late-stage clinical development.
Experience managing drug substance and drug product service providers in analytical matters.
Extensive knowledge of GLP and cGMP requirements, appropriate regulatory guidance and current industry practices for analytical development.
Experience in writing CMC sections for Regulatory submissions (IND experience required; NDA experience highly desirable).
Excellent computer skills (e.g., Microsoft Office, Excel, Project).
Ability to effectively manage multiple priorities and projects.
Preference given to applicants able to work (hybrid) from Thousand Oaks or San Francisco, CA offices.
$117k-184k yearly est. 5d ago
Research Scientist - Controlled 3D Generation
Stability.Ai
Principal research scientist job in Los Angeles, CA
About the Role We're seeking a ResearchScientist passionate about 3D generation, flow matching, and diffusion models. You'll help advance the frontier of controllable 3D content creation-building models that generate consistent, editable, and physically grounded 3D assets and scenes.
What You'll Do
* Conduct cutting-edge research on flow-matching, diffusion, and score-based methods for 3D generation and reconstruction.
* Design and implement scalable training pipelines for controllable 3D generation (meshes, Gaussians, NeRFs, voxels, implicit fields).
* Develop techniques for conditioning and control (text, sketch, pose, camera, physics) and multi-view consistency.
* Analyse model behaviour through ablations, visualisations, and quantitative metrics.
* Collaborate with cross-disciplinary research, graphics, and infrastructure teams to translate research into production-ready systems.
* Publish results at top-tier venues and work with interns.
What You Bring
* PhD (or equivalent experience) in Machine Learning, Computer Vision, or Computer Graphics.
* Published work on diffusion, flow-matching, or score-based generative models (2D or 3D).
* Strong engineering and problem-solving abilities: experience with PyTorch, JAX, or CUDA-level optimisation.
* Understanding of 3D representations (meshes, Gaussians, signed-distance fields, volumetric grids, implicit networks).
* Solid grasp of geometry processing, multi-view consistency, and differentiable rendering.
* Ability to scale experiments efficiently and communicate complex results clearly.
Bonus / Preferred
* Experience generating coherent 3D scenes with multiple interacting objects, lighting, and spatial layout.
* Familiarity with scene-level control (object placement, camera path, simulation, or text-to-scene composition).
* Knowledge of video-to-3D, image-to-scene, or 4D temporal generation.
* Background in physically-based rendering, simulation, or world-model architectures.
* Track record of impactful publications or open-source releases.
Equal Employment Opportunity:
We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or other legally protected statuses.
$91k-152k yearly est. Auto-Apply 60d+ ago
Research Scientist
California Institute of Technology 4.5
Principal research scientist job in Pasadena, CA
Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do.
Join us and be a part of the diverse Caltech community.
Job Summary The selected candidate will contribute to a growing research program in Artificial Intelligence and Mathematics.
Working under the guidance of senior researchers, the individual will help apply machine learning methods, with a focus on reinforcement learning, to mathematical problem solving.
The role emphasizes hands-on experimentation, algorithmic exploration, and collaborative research, rather than independent program leadership.
This position is well-suited for candidates in the early stages of their career.
Essential Job Duties Conduct research using machine learning and reinforcement learning techniques to explore mathematical problem solving.
Assist in the development, testing, and refinement of algorithms for mathematical reasoning.
Collaborate closely with senior researchers and other team members to advance project objectives.
Contribute to data collection, analysis, and the preparation of research results.
Assist in drafting manuscripts for publication in scientific journals and preparing materials for conference presentations.
Participate in group meetings, research discussions, and collaborative planning sessions.
Basic Qualifications Master's degree Computer Science, Applied Mathematics, Mathematics, Statistics, Electrical Engineering, Physics, or a closely related field plus two years of relevant work experience.
Experience with machine learning, especially reinforcement learning.
Strong background in mathematical reasoning and problem-solving.
Proven track record of research excellence demonstrated through publications and projects.
Strong communication and collaboration skills.
Preferred Qualifications PhD in Computer Science, Applied Mathematics, Mathematics, Statistics, Electrical Engineering, Physics, or a closely related field.
Required Documents Resume.
$74k-114k yearly est. 39d ago
Associate Scientist Analytical Chemistry
Provivi 3.9
Principal research scientist job in Santa Monica, CA
We are a multi-national, Santa Monica-based company, founded in 2013 by Caltech scholars: Professor Frances Arnold, Pedro Coelho, and Peter Meinhold. We're rethinking pest control as innovators in pheromone technology, the engineers and creators of a family of safe and effective pest control solutions for major damaging insects. We are hiring the very best and brightest people to expand our impact.
Role Description
As a member of the Provivi's technology team, you will have a vital role in developing and validating analytical methods for detection, identification, and quantification of small molecules found in Provivi's proprietary chemical and biochemical processes as well as pheromone components in formulated products. Specifically, the successful candidate will develop and validate GC, GCMS, HPLC, and HPIC methods, as well as establish quality control protocols for Provivi's commercial products, provide hands-on technical assistance to maintain analytical equipment in good working orders, and analyze samples supporting various projects. Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems, are essential.
Responsibilities Include
Develops, validates, and standardizes GC, HPLC, HPIC analytical methods for detection, identification, and quantification of small molecules found in chemical and biochemical processes, and formulated products.
Extracts, analyzes and evaluates material and products at all stages of development process under stringent quality and time requirements.
Prepares research reports, invention disclosures, and Standard Operating Procedures for internal and external use.
Reviews data for technical content and regulatory compliance.
Ensures analytical equipment is maintained in good working order; troubleshoots and performs minor repairs as needed.
Anticipates additional resources, consumables, and equipment requirements as needed to ensure that work can be completed within the budgeted time.
Remains current with analytical chemistry literature and champions the implementation of new technology.
Maintains a safe and orderly laboratory and ensures compliance with all safety policies and practices.
Qualifications & Skills Include
M.S. in analytical chemistry or equivalent, or bachelor's in chemistry with 2 additional years of analytical lab experience
A minimum of 0-2 years of biotech and chemical industrial experience with hands-on experience in analytical chemistry.
A good understanding of analytical chemistry, organic chemistry, and chemical engineering principles.
Demonstrated practical ability to develop methods for isolation, characterization, and quantification of small molecules found in chemical and biochemical processes and formulated products using conventional chromatography techniques and analytical instruments including GC, GCMS, HPLC, and NMR.
Must be skilled in operation of chromatographic data acquisition and processing software packages such as Chromeleon, ChemStation, and other software tools for data reduction and presentation.
Excellent written, reporting, and verbal communication skills
Proficient in using Microsoft Office suite including Word, Excel, and Power Point.
Ability to prioritize responsibilities and multi-task in a fast-paced environment with changing priorities
Must be highly motivated and capable of working independently to deliver results under tight deadlines
Able to lift 15 - 40 pounds.
Diversity and Equal Opportunity Employment
Provivi is an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veterans status, or any other legally-protected factors.
$76k-115k yearly est. 4d ago
Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute
Dev 4.2
Principal research scientist job in Lawndale, CA
Company DescriptionJobs for Humanity is partnering with CEDARS-SINAI to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located.
Company Name: CEDARS-SINAI
Job Description
Principal Investigator, Ivan Cokic, PhD, is looking for a Postdoctoral Scientist to join the Biomedical Imaging Research Institute!
The Cedars-Sinai Biomedical Imaging Research Institute (BIRI) is an interdisciplinary research program established in 2010 to develop and apply state-of-the-art imaging technologies to today's most pressing translational research and clinical questions. Led by founding director Debiao Li, PhD, the program builds on Cedars-Sinai's clinical and research strefngths, with the ultimate goal of using novel medical imaging technology to improve the diagnosis, treatment and prevention of diseases. The BIRI team is dedicated to educating and training the next generation of the brightest imaging scientists and clinicians through our robust pre-/post-doctoral and visiting-scientist training programs. In addition, we have numerous research collaborations with leading imaging researchers. To learn more, please visit Biomedical Imaging Research Institute | Cedars-Sinai.
In this role, the Postdoctoral Scientist will be expected to work independently under the direction of Dr. Cokic and in close cooperation, as well as consultation, with other research staff. This interdisciplinary preclinical project combines advanced cardiac imaging, cardiac (electro)physiology, cardioimmunology, cardiovascular pathology, and metabolomics. In addition, assisting with investigating clinical applications of novel magnetic resonance imaging (MRI) and positron emission tomography (PET) techniques for diagnosing, phenotyping and risk-stratifying subjects with MI. As a Postdoctoral Scientist, perform routine and complex laboratory procedures throughout the training period and may develop, adapt, and implement new research techniques and protocols.
Primary Job Duties and Responsibilities:
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
May participate in publications and presentations as author or co-author.
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I.
Analyzes, interprets, summarizes and compiles data.
Operates and maintains equipment and instruments.
Department-Specific Responsibilities:
Handling of large animal (farm pigs, Yucatan minipigs, etc.) models of myocardial infarction (MI).
Writing Institutional Animal Care & Use Committee (IACUC) protocols.
Coordinating animal surgeries with team of designated research technologists.
Designing and coordinating imaging experiments on BIRI's PET/MRI scanners with team of designated research technologists.
Analysis of cardiac MRI and PET imaging data as well as histopathology and metabolomics data.
Perform advanced data and statistical analysis and will communicate scientific findings in papers and conference presentations.
Assist with database creation and management, supervision of undergraduate/graduate students.
Education:
Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required.
Experience and Skills:
Highly motivated and works independently on research projects designed by a mentor (typically the PI) within the area of specialization.
Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Highly motivated with a proven track of record of publications.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.
Knowledge of safety standards, operation, and maintenance of specialized equipment.
Working Title: Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute
Department: BMS - BioMed Imaging Res Inst
Business Entity: Cedars-Sinai Medical Center
Job Category: Academic/Research
Job Specialty: Postdoctoral
Position Type: Full-time
Shift Length: 8 hour shift
Shift Type: Day
Base Pay:$64,500.00 - $93,600.00
$64.5k-93.6k yearly 60d+ ago
Learn more about principal research scientist jobs
How much does a principal research scientist earn in Simi Valley, CA?
The average principal research scientist in Simi Valley, CA earns between $105,000 and $241,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.
Average principal research scientist salary in Simi Valley, CA