Scientist jobs in Lemon Grove, CA

, please email ********************** We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines. RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions. The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery. Duties and Responsibilities: Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform. Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery. Monitor and evaluate the performance of AI/ML models and drug discovery solutions. Utilize software engineering best practices to develop complex AI applications at scale. Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML. Proactively scope and deploy novel computational methods and digital technologies. Education and/or Experience: Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field. Expertise in deep learning and machine learning. Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow) Knowledge, Skills, and Abilities: Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience. Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods. Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs). Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins. Fluency in scientific programming and tool development with Python, R, or equivalents. Proficiency in C++ or Java is a plus. Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications. Experience with software development good practices, including code versioning, documentation, and testing. Experience with cloud computing. Creative, open-minded, and passionate about scientific research. Demonstrated ability to thrive in a team environment. Strong interpersonal, collaborative, organizational, and presentation skills. Understanding of RNA therapeutic modality discovery and development. No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California. Supervisory Responsibilities: This position does not currently have direct reports. Perks and Benefits: Generous employer-paid healthcare for Medical, Dental, and Vision. 100% Employer Paid Life, STD and LTD 401(k) Employer Match Generous Vacation and Sick Leave 13 Holidays Closed over the Christmas and New Year Holiday Break

You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate . Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams , governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s , analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings , seeks opportunities to further improve quality and efficiency of clinical procedures; MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 2 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 5 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 7 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval. Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance. Experience working on large data sets. Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience building partnerships across the company to achieve the needs of the program. PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology. Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned. Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities. Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes. Leverages knowledge and support from others related to overall objectives , strategy, critical issues, and policies. Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes. Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies . Work Location Assignment: This is a Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical

Design and conduct laboratory studies utilizing a variety of sample analysis platforms primarily on human specimens for biomarker and disease understanding applications in psoriasis programs Conduct ex vivo functional, target engagement functional assays with human and non-human PBMCs. Utilize flow cytometry/FACS, immunoassays, gene expression profiling, cell and tissue culture, nucleic acid extractions, and other platforms relevant to profiling of immune cells and skin biology Initiate or help manage projects with external vendors or collaborators Execute research activities under limited supervision Provide critical analysis and interpretation of data Deliver reporting and communication of results, and participate in scientific discussions Experience & Expertise A minimum of a Ph.D. degree or a Master's degree with 3 or more years of related experience is required. Experience with immunoassays, flow cytometry/FACS and tissue culture is required, and a background in inflammation or immunology research is strongly preferred. Experience with tissue culture and functional cellular immunology assays desired Experience with molecular biology including RNA, DNA preparation and analysis including RT QPCR, microarrays, RNAseq desired. Ability to work independently with minimal supervision in a team environment. Proficiency in working with complex data sets and interpreting and presenting results. Knowledge of data analysis and visualization applications. Effective oral, written and interpersonal communication skills. Technical Knowledge and Skills: Experience in tissue culture of immune cells including ex vivo assays with primary blood and tissue cells such as cell differentiation, activation, cytokine production. Experience in protein detection assays including ELISA, MSD, Singulex, etc. Experience with FACS immunophenotyping and sorting of human cells. Experience in psoriasis research would be an advantage, as would familiarity with analysis of samples from clinical studies and other aspects of translational research. Qualifications Education Qualification: Only MS or PhD candidates are needed. Additional Information

Scientist, Life Science Organic Chemistry Join our dynamic and cutting-edge research program focused on the health and chemical senses. As part of our multi-disciplinary discovery team, you will collaborate with our global R&D community to explore receptor-driven discovery of new bioactive ingredients and their industrial applications. We are seeking an exceptional and goal-oriented expert in the field of organic and medicinal chemistry. The ideal candidate will be an accomplished synthetic organic chemist with a proven track record of conducting science-based and computer-aided discovery of new bioactive and/or bio-functional molecules. DSM-Firmenich is a leading global provider of innovative solutions in nutrition, health, and sustainable living. We combine scientific expertise with cutting-edge technology to develop sustainable solutions that improve the quality of life for people today and for future generations. Our collaborative approach and commitment to excellence make us a trusted partner for our customers worldwide. **Your Key Responsibilities:** + Leverage expertise in organic chemistry and medicinal chemistry to design and synthesize small molecules with optimal properties. + Partner cross-functionally with other internal Science and Research domains including Biology, Computational Science, AI, and Machine Learning teams to speed up discovery + Work with Clinical Research Organizations to maximize the synthesis of libraries and specific compounds. + Maintain and understanding of relevant cutting-edge science (e.g. new chemistries & medicinal chemistry techniques and principles) and technology trends (e.g. automation) to propose new creative solutions or ideas to address technology gaps and save cost. + Analyse and present chemistry and SAR data at internal and external meetings and conferences + Draft and submit invention disclosure, publication manuscripts, and lab reports **We Bring:** + A science led company with cutting edge research and creativity everywhere - from Science and Research breakthroughs to sustainability game-changers, you'll work on what's next + A unique career paths with growth that keeps up with you - you join an industry leader that will develop your expertise and leadership + A chance to impact millions of consumers every day + A community where your voice matters + A culture that lifts you up - with collaborative teams, shared wins, and people who cheer each other on. + Competitive pay, career growth opportunities, and outstanding benefit programs. **You Bring:** + Up to 5 years ofpost-PhD experience (or equivalent) in organic or medicinal chemistry in an academic, biotechnology, or pharmaceutical environment + Knowledge in modern medicinal chemistry and lead optimization techniques, including multi-parameter bioactivity and physicochemical properties optimization + Strong synthetic and analytical chemistry skills with ability to design and implement multi-steps synthesis and characterization of complex molecules + Familiarity with molecular modeling and other computational tools useful for speeding up the discovery of bioactive small molecules + Great team player and excellent communicator with a strong drive for collaboration, excellence, and impact + Ability to innovate and thrive in a multidisciplinary environment The salary or hourly wage scale provided reflects the pay range dsm-firmenich expects to pay the successful candidate for the position. Individual pay offered will be based on the applicant's job-related skills, experience, relevant education, or training, and primary work location. This position is also eligible for bonuses and benefits, which are not included in the pay scale provided. Salary $97,000-$139,000. **About dsm-firmenich** At dsm-firmenich, we don't just meet expectations - we go beyond them. Join our global team powered by science, creativity, and a shared purpose: to bring progress to life. From elevating health to making fortified food and sustainable skincare, the impact of your work here will be felt by millions - every single day. Whether it's fragrance that helps you focus, alternative meat that's better for the planet, or reducing sugar without losing flavor, this is where you help shape the future of nutrition, health, and beauty for everyone, everywhere. And while you're making a difference, we'll make sure you're growing too. With learning that never stops, a culture that lifts you up and the freedom to move across businesses, teams, and borders. Your voice matters here. And your ideas? They're essential to our future. Because real progress only happens when we **go beyond, together** . **The application process** Interested in this position? Please apply online by uploading your resume in English. **Inclusion, belonging and equal opportunity statement** At dsm-firmenich, we believe being a force for good starts with the way we treat each other. When people feel supported, included, and free to be themselves, they do their best work - and that's exactly the kind of culture we're building. A place where opportunity is truly equal, authenticity is celebrated, and everyone has the chance to grow, contribute, and feel they belong. We're proud to be an equal opportunity employer, and we're serious about making our hiring process as fair and inclusive as possible. From inclusive language and diverse interview panels to thoughtful sourcing, we're committed to reflecting the world we serve. We welcome candidates from all backgrounds - no matter your gender, ethnicity, sexual orientation, or anything else that makes you, you. And if you have a disability or need any support through the application process, we're here to help - just let us know what you need, and we'll do everything we can to make it work. **Agency statement** We're managing this search directly at dsm-firmenich. If you're applying as an individual, we'd love to hear from you. We're not accepting agency submissions or proposals involving fees or commissions for this role

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • The new Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams. • This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as an Associate Scientist. • The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays. • A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. • Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel. Qualifications A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. Additional Information Sneha Shrivastava Technical Recruiter (Clinical/Scientific) Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: ************ | Fax: ************ Connect with us on - LinkedIn | Facebook | Twitter

WuXi AppTec Biology, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services. We are seeking a highly motivated and versatile scientist to advance our neuroscience platforms and broader discovery programs aimed at developing therapies for neurodegenerative, neuroinflammatory, and other complex diseases. The successful candidate will design, develop, and execute sophisticated in vitro assays using human iPSC-derived neurons, primary neuronal cells, co-culture systems, and additional cellular models. In addition to neuroscience, this role will also support cross-functional projects involving general cell biology, immunology, and translational assays. Strong technical depth, assay development expertise, and the ability to collaborate effectively in a multidisciplinary environment are essential. **Responsibilities** - Design, optimize, and execute in vitro neuroscience assays using iPSC-derived neurons, astrocytes, primary neuronal cells, and other CNS-relevant cell types. - Develop and characterize co-culture models (e.g., neuron-microglia, neuron-astrocyte, multi-lineage systems) to study disease mechanisms. - Support discovery programs with key functional readouts, including neurite outgrowth, neuronal survival, synaptic activity, and high-content imaging. - Perform molecular and cellular analyses such as qPCR, flow cytometry, ELISA, imaging-based assays, and protein/RNA quantification. - Contribute to non-neuroscience projects, including general cell biology assays, immune cell functional assays, iPSC-derived non-CNS lineages, and other translational models as needed. - Independently manage multiple projects, ensuring rigorous experimental design, high-quality execution, and reproducible data generation. - Prepare clear and well-structured data summaries, technical reports, and presentations for internal teams and external partners. **Qualifications** - Ph.D. in Neuroscience, Stem Cell Biology, Cell Biology, or a related field with 4-6 years of postdoctoral or industry research experience. - Strong knowledge of neurodegenerative and neuroinflammatory diseases, including relevant cellular and molecular mechanisms. - Extensive hands-on expertise with iPSC-derived neuronal culture systems and advanced cellular neuroscience models. - Demonstrated experience developing and applying co-culture assays and functional neuronal readouts (e.g., neurite outgrowth, synaptic activity, survival assays). - Experience with organoid or 3D culture systems is a strong plus. - Broader expertise in general cell biology, immunology, or iPSC-derived non-CNS cell types is highly valued. - Proven ability to manage multiple projects effectively, with strong organizational and multitasking skills. - Excellent written, oral, and interpersonal communication skills. Physical Requirements: - Must be able to work in an office environment with minimal noise conditions - Must be able to work in a lab setting with exposure to Animals/biohazards /Chemicals (List - specific Chemicals) - Must not have animal allergies to applicable species in this facility. - Must be able to work in environment with variable noise levels. - Ability to stand/Sit/walk for long periods of time. - Ability to Lift 10 lbs routinely. - Ability to push/pull 10 lbs. routinely/often/occasionally - Clarity of vision. - Ability to identify and distinguish colors. - Must be able to perform activities with repetitive motions. - Ability to climb ladders/stairs/scaffolding. - Ability to work in variable temperatures high to freezing. - Inside/outside working conditions. Anticipated base pay range: $80,322 to $104,000 An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management. **Need help finding the right job?** We can recommend jobs specifically for you! An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability (************************************************************************************************** **Job Locations** _US-CA-San Diego_ **Job ID** _2025-13872_

Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience Responsibilities: The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat Qualifications Minimum Bachelor's degree in a biological science discipline Additional Information College degree or HS Diploma with +5 years biopharmaceutical industry experience

Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************

**Be visionary** Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, deepwater oil and gas exploration and production, medical imaging and pharmaceutical research. We are looking for individuals who thrive on making an impact and want the excitement of being on a team that wins. **Job Description** **Job Summary:** TAPI is seeking a highly experienced Scientist, with a proven record of developing Gas Chromatography Instrumentation, to join our Research and Development team. This role will focus on the development of new GC-based instrumentation to support innovation in analytical chemistry and production workflows. The ideal candidate will bring deep expertise in gas chromatography, method development, and instrumentation, along with a strong background in production or R&D environments. **Key Responsibilities** + Lead the design and development of advanced gas chromatography (GC) methods and instrumentation. + Operate, maintain, and troubleshoot GC instruments including FID, DBD, FPD, and PID detectors. + Collaborate with cross-functional teams to support product development and quality assurance. + Perform sample preparation, calibration, and quantitative analysis with high precision. + Document and validate analytical methods in compliance with internal and regulatory standards. + Mentor junior technicians and contribute to technical training initiatives. + Communicate findings clearly through technical reports and presentations. **Minimum Qualifications** Education: Bachelor of Science (B.Sc.) in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field. Experience: Minimum of 10 years of relevant work experience in a R&D or Manufacturing environment. Technical Expertise: - Proficiency in GC method development, validation, and troubleshooting. - Proven experience with GC instruments including FID, DBD, FPD, and PID. - Familiarity with chromatography data systems such as Chromperfect . - Strong understanding of sample preparation, calibration, and quantitative analysis. Soft Skills: - Exceptional analytical thinking and attention to detail. - Excellent written and verbal communication skills. **Preferred Qualifications** + Experience in developing GC technologies for novel applications. + Knowledge of regulatory standards and documentation practices (e.g., cGMP, SOPs). + Ability to work independently and manage multiple projects simultaneously. **Why Join TAPI?** At TAPI, you'll be part of a dynamic team driving innovation in analytical science. We offer competitive compensation, a collaborative work environment, and opportunities for professional growth. **Salary Range:** $113,600.00-$151,400.000 **Pay Transparency** The anticipated salary range listed for this role is only an estimate. Actual compensation for successful candidates is carefully determined based on several factors including, but not limited to, location, education/training, work experience, key skills, and type of position. Teledyne conducts background checks on qualified applicants who receive a conditional offer of employment in accordance with applicable laws, regulations and ordinances. Background checks may include, but are not limited to, education verification, employment history and verification, criminal convictions, Motor Vehicle Report (MVR & driving history), reference check, credit checks/credit history and drug testing. All qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. Teledyne and all of our employees are committed to conducting business with the highest ethical standards. We require all employees to comply with all applicable laws, regulations, rules and regulatory orders. Our reputation for honesty, integrity and high ethics is as important to us as our reputation for making innovative sensing solutions. Teledyne is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic or non-merit based factor made unlawful by federal, state, or local laws. You may not realize it, but Teledyne enables many of the products and services you use every day **.** Teledyne provides enabling technologies to sense, transmit and analyze information for industrial growth markets, including aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, energy, medical imaging and pharmaceutical research.

Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities * Maintain a well-documented laboratory notebook * Track progress against project timelines, generate regular status updates, and communicate progress and issues to management * Perform tasks across projects * Manage time effectively to meet deadlines * Adhere to safe laboratory practices * Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: * B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry * 0-3 years of experience working in a chemistry laboratory * Experience with a wide range of analytical techniques, especially HPLC * Ability to quickly learn new procedures and techniques Preferred: * Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting * Experience with solid-phase peptide synthesis (automated and/or manual) * Prior experience in a pharmaceutical or biotechnology environment

How you will contribute: We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company. What you will be working on: Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing. Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes. Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color. Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing. Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research. What you bring to Plantible: B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering. 3 to 5+ years of industry experience in assay development in an industrial environment. Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer. Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes. A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action. Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred. Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills. Excellent verbal and written communication and presentation skills. Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment. Thrive in a fast-paced environment where the primary focus is on simplification and optimization. Choose Plantible Foods Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment. At Plantible we are continually working on our offerings to foster the best team. Check it out! Competitive health and wellness benefits Medical, Dental and Vision Insurance Discretionary Unlimited PTO Program Paid Holidays 401k Program Career Stipend Career development and growth opportunities Working in a rapidly growing, flexible and entrepreneurial environment Team building and company-wide events Financial support with your relocation, if necessary, ensuring a smooth transition Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time. If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Universal Sequencing Technology, a biotech startup headquartered in Canton, MA (~15 miles southwest of Boston) with a location in Carlsbad, CA, is looking for a highly talented Manufacturing Scientist to join the team, located in Carlsbad, CA.* We are excited to provide novel DNA sequencing technology for the Next Generation Sequencing (NGS) platforms that enables many previously unachievable applications. This position is a unique opportunity to commercialize a novel NGS library technology, TELL-Seq TM , an ultra-low input single tube linked read technology which enables many previously unachievable long read applications and to develop disruptive single cell applications. The incumbent will have hands on experience on DNA conjugation and amplification, in-process quality control assay development, filling and labeling experience and capability to increase scalability using technology, equipment, manpower, etc… to meet increasing demand. S/He will work closely with R&D and manufacturing teams to scale up production procedure and accelerate product commercialization. S/He must have excellent documentation skills and strong interpersonal skills, be driven by making high quality products, and enjoy working in a multi-disciplinary environment. Key Responsibilities Engineer scale up procedures for bulk production, filling process and kit assembly Optimize reagent formulation and process for bulk DNA amplification in emulsions Develop in-process quality control assays (analytical) for reagent formulations, productions, characterization and identification Execute well thought out experiments, record results accurately along with in-depth analysis and reports that will be reviewed, approved and filed in QA Create/update manufacturing production protocols, execute protocol and/or train others to do the same Work with other manufacturing personnel to make bulks, fill reagents and assemble kits. This is a hands on, in the lab position Work with Inventory Management to ensure proper handling, storage, usage and accountability of all materials needed to produce or test products Manage and execute stability sampling, storage and testing Manage tasks, projects and timeline to meet deliverable on time and on quality. Manage resources accordingly for the same Write, review and revise SOP's through a Document Change Order. Initiates, Investigates and write up non-conformance reports. Required Skills and Background M.Sc. or Ph.D. in chemistry, chemical engineering, molecular biology, biochemistry, biology, biotechnology or a similar field (B.S. with exceptional experience WILL be considered) Prior GMP and GDP experience is required. Hands on experience with magnetic beads (suspension material), oligo conjugation and quantification Direct experience in nucleic acid amplification technologies, particularly in emulsion PCR Experience in Lean Six Sigma project implementation is a plus 5-7 years experience in a reagent GMP environment Detail oriented and very good documentation skill Hands on leaders perform well in this environment

Research Biologist needs 2-3 years experience Research Biologist requires: Degree in biology Laboratory equipment and procedures. MS Office Lab techniques Research Biochemistry Cell biology Experience in running biochemical and immunological assays. Research Biologist duties: Ø Conduct experiments to identify and validate drug targets. Ø Support assay design, optimization, validation, and data analyses. Ø Design and execute molecular and cell biology experiments. Ø Troubleshoot and analyze complex data in support of drug discovery projects. Ø Presentation of results and conclusions both orally and written.

Who We Are: At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do: Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. ( *in collaboration with AbbVie ) About the Role:Our dynamic team is seeking a motivated, collaborative, and experienced TEMP scientist to support biologics characterization for discovery and lead optimization teams. The qualified individual will work closely with team members to design, develop, and execute assays to deliver robust and high-quality data to drive decision-making. The position requires excellent scientific, technical and laboratory skills, strong organizational and communications skills, and enthusiasm for contributing to a fast-paced organization focused on discoveries of novel and differentiated therapeutic candidates. _ Your Contributions (include, but are not limited to): Develop and perform large molecule analytical and characterization assays under the supervision of senior scientists, including identity testing by intact mass and/or subunit analysis, glycan profiling, primary structure and PTM analysis by peptide mapping Perform data analysis, interpret results, draft report and document experiment in ELN, support stakeholders including discovery biology, protein engineering and lead optimization Perform routine maintenance of HPLC and MS systems, prepare mobile phases, execute calibration and cleaning procedures, coordinate regular preventative maintenance troubleshooting under the supervision of team leaders Execute sample preparation workflows, such as buffer exchange, immunoprecipitation, reduction and alkylation, enzymatic digestion Manage sample receiving, testing and storage, maintain and track consumables including columns, buffer solutions, enzymes and chemicals Track and document assay performance Provides recommendations to improve on process efficiency and research quality Other duties as assigned Requirements: BS/BA degree in scientific field and 2+ years of analytical chemistry experience; OR MS/MA degree in scientific field and some relevant industry experience OR PhD in related field Experience in protein analytical method development for identification and quantitation is required, including physicochemical and MS-based methods Good knowledge and demonstrated ability working with large molecule separation methods including reversed-phase HPLC, analytical SEC and CE-SDS Solid understanding of mass spectrometry operating principles, including ionization, ion transfer, gas-phase fragmentation, and mass analyzers Experience on high-resolution TOF and/or orbitrap mass analyzers is a plus Working knowledge of protein chemistry, amino acid composition, primary structure, post-translational modifications, higher-order structure and protein-protein interactions is a plus Collaborative and highly motivated Ability to work as part of a team Strong computer skills and experience with Prism, Excel, Word, etc. Good communications, problem-solving, analytical thinking skills Detail oriented Ability to meet deadlines Good project management skills #LI-LS1 Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within our Late-Stage Oncology portfolio. **Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate. Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, **OR** MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO **OR** BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 2 - 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance Experience working on large data sets Proficiency with Microsoft Office and relevant scientific software Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations Experience building partnerships across the company to achieve the needs of the program **Demonstrates passion for helping patients with cancer and for the science of oncology Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. Work Location Assignment:** This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. **Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy