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Senior applications scientist vs principal scientist

The differences between senior applications scientists and principal scientists can be seen in a few details. Each job has different responsibilities and duties. It typically takes 2-4 years to become both a senior applications scientist and a principal scientist. Additionally, a principal scientist has an average salary of $119,982, which is higher than the $105,538 average annual salary of a senior applications scientist.

The top three skills for a senior applications scientist include software development, data collection and next-generation sequencing. The most important skills for a principal scientist are oncology, data analysis, and drug discovery.

Senior applications scientist vs principal scientist overview

Senior Applications ScientistPrincipal Scientist
Yearly salary$105,538$119,982
Hourly rate$50.74$57.68
Growth rate17%17%
Number of jobs56,96680,899
Job satisfaction--
Most common degreeBachelor's Degree, 49%Bachelor's Degree, 51%
Average age4141
Years of experience44

What does a senior applications scientist do?

A senior applications scientist imports and exports data as well as managing user interface security. They must identify issues in their company's database system and resolve them. They are also responsible for designing equipment to automate database systems.

What does a principal scientist do?

A Principal Scientist is focused on leading scientific teams and conducting research. They ensure that their teams have the resources to properly perform research tasks.

Senior applications scientist vs principal scientist salary

Senior applications scientists and principal scientists have different pay scales, as shown below.

Senior Applications ScientistPrincipal Scientist
Average salary$105,538$119,982
Salary rangeBetween $69,000 And $159,000Between $84,000 And $169,000
Highest paying CityRohnert Park, CASan Francisco, CA
Highest paying stateRhode IslandCalifornia
Best paying companySchrödingerPayPal
Best paying industryManufacturingFinance

Differences between senior applications scientist and principal scientist education

There are a few differences between a senior applications scientist and a principal scientist in terms of educational background:

Senior Applications ScientistPrincipal Scientist
Most common degreeBachelor's Degree, 49%Bachelor's Degree, 51%
Most common majorChemistryChemistry
Most common collegeDuke UniversityDuke University

Senior applications scientist vs principal scientist demographics

Here are the differences between senior applications scientists' and principal scientists' demographics:

Senior Applications ScientistPrincipal Scientist
Average age4141
Gender ratioMale, 67.1% Female, 32.9%Male, 76.8% Female, 23.2%
Race ratioBlack or African American, 6.5% Unknown, 4.1% Hispanic or Latino, 9.8% Asian, 26.3% White, 53.1% American Indian and Alaska Native, 0.1%Black or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.6% Asian, 26.4% White, 53.4% American Indian and Alaska Native, 0.1%
LGBT Percentage8%8%

Differences between senior applications scientist and principal scientist duties and responsibilities

Senior applications scientist example responsibilities.

  • Manage study protocols and study conduct, intimately involve in the toxicology and pharmacokinetic study protocol development process.
  • Design, develop and implement DNA base assays and immunoassays.
  • Subject matter expert for applications of a pathogen detection system base on principles of PCR and mass spectrometry.
  • Develop, validate and implement robust methods for pharmacokinetic, immunogenicity (ADA) and immunodepletion ELISAs, and cell based-bioassays.
  • Develop novel applications for FDSS6000 HTS instrument.
  • Conduct genotyping and phenotyping of models as required.

Principal scientist example responsibilities.

  • Manage pediatric dose development project, technology transfer project and alternate API supplier qualification project on budget and on schedule
  • Provide development of and line support for assign immunoassay reagents, calibrators and controls.
  • Transfer controls to manufacturing for product launch and include all require studies, testing and documentation under GMP guidelines.
  • Maintain several lab documents for ISO certification.
  • Understand drug metabolism and pharmacokinetics and design stable molecules.
  • Image visualization and manipulation of background plates for animation and post-processing.
  • Show more

Senior applications scientist vs principal scientist skills

Common senior applications scientist skills
  • Software Development, 16%
  • Data Collection, 10%
  • Next-Generation Sequencing, 9%
  • Data Analysis, 5%
  • Customer Support, 5%
  • Technical Support, 5%
Common principal scientist skills
  • Oncology, 7%
  • Data Analysis, 6%
  • Drug Discovery, 5%
  • GMP, 3%
  • Experimental Design, 3%
  • Clinical Trials, 3%

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