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  • Associate Principal Scientist, PharmaR&D at Tempus - Boston, United States

    Victrays

    Senior scientist job in Boston, MA

    Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Responsibilities Partner with our pharma clients to design, develop and execute computational research leveraging the Tempus platform to advance drug R&D programs. Become an expert in Tempus multimodal clinical and genomic data. Analyze and integrate large, diverse clinical and molecular datasets to extract insights and drive new research opportunities. Lead scientific and technical interactions with clients to co-architect solutions and projects. Become an expert in current and prospective clients' strategies, pipelines, and portfolios to identify where the Tempus platform can add value and collaborate with sales teams to realize that value. Collaborate with Research, Engineering & Data Science teams to develop and deliver innovative computational solutions. Drive continual improvement of the Tempus platform by communicating client feedback, staying ahead of research and industry trends, championing opportunities for new markets, and influencing our leadership and global account strategy teams. Work with Product and Engineering teams to streamline the workflow of computational analyses. Document, summarize, and communicate highly technical results and methods clearly to non-technical audiences. Author whitepapers and peer-reviewed manuscripts illustrating the value of multimodal analysis and AI in drug discovery. Qualifications Education to Masters or Ph.D. level combining quantitative and/or computational skills, e.g., Computational Biology, Biostatistics/Statistical Genetics, Bioinformatics, Biomedical Informatics, Biometrics, Data Science for Health, or similar. Biological or medical knowledge, e.g., Human Disease, Genetics/Genomics, Molecular Biology, or Immunology. Comfort in a client-facing role. Proficient in R or Python. Strong understanding of the molecular nature of human disease. Expert in delivering actionable insight from transcriptomic data sets. Experience with Clinical Trial Data and/or Real World Evidence. Experience with integrative methods to model multi-modal clinical and/or omics data. Experienced in SQL. Thrive in a fast‑paced environment and willing to shift priorities seamlessly. Experience in any of the following will also be beneficial: drug R&D oncology; immunology; single cell or spatial transcriptomics; mechanistic modeling and inference; knowledge and graph‑based AI techniques. CHI: $170,000-$230,000 NYC/SF: $180,000-$250,000 The expected salary range above is applicable if the role is performed from Massachusetts and may vary for other locations (California, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. Massachusetts Applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. #J-18808-Ljbffr
    $180k-250k yearly 1d ago
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  • Principal Scientist, ADME-PK

    Dyne Tx

    Senior scientist job in Waltham, MA

    Our commitment to people with neuromuscular diseases Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more ************************* and follow us on X, LinkedIn and Facebook. Role Summary: The Principal S cientist , ADME-PK in Preclinical Development (PCD) department utilize s their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance Dyne 's efforts surrounding delivery of therapeutic payloads to muscle and CNS tissues with the FORCE platform . This role is based in Waltham, MA. Primary Responsibilities Include: Design and execute internal/external preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of Dyne's drug candidates Represent PCD as the ADME-PK subject matter expert on discovery and program teams Partner with and support Research, Toxicology, Translational Biomarkers, Clinical, Regulatory, Project Management and other Dyne departments Collaborate with Clinical Pharmacology/Pharmacometrics to develop quantitative tools to translate PK/PD relationship from preclinical to clinical Author high quality Regulatory documents including INDs, CTAs, and NDA/BLA filings. Prepare strategic and science-based ADME strategies that meet regulatory requirements and program goals Facilitate strategic scientific communication via meetings, abstracts and manuscripts Education and Skill Requirements: PhD in Pharmacokinetics, Pharmacology, Pharmaceutics, Biomedical Sciences or other relevant field with >6 years (MS with >8 years, BS with >12 years) of experience in the biopharmaceutical industry, with evidence of drug development experience Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamics and bioanalytical principles F amiliarity with regulatory submission including FIH dosing strategy is highly desirable Proficient in using WinNonlin or other pharmacokinetic software Excellent communication (verbal and written) and presentation skills, as well as interpersonal skills and the ability to represent PCD in a team environment Experience with PK characterization of protein therapeutics or antibody-drug conjugates (ADCs) is desired #LI-Onsite MA Pay Range $159,000 - $195,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. #J-18808-Ljbffr
    $159k-195k yearly 3d ago
  • Sr. Principal Scientist

    The University of Texas Md Anderson Cancer Center 4.3company rating

    Senior scientist job in Boston, MA

    The role will be responsible for all operations involved with routine manufacturing and quality control testing of radiopharmaceuticals produced in Aktis' GMP laboratory (Boston, MA), including but not limited to the list below. This role will report to the Director of Clinical Trial Manufacturing. Salary Range: $136,800.00 To $189,200.00 Annually Responsibilities Manual and automated production of radiopharmaceuticals in a GMP facility QC testing of radiopharmaceuticals Execution and upkeep of the facilities' environmental monitoring program Accurate and timely preparation and completion of manufacturing and Quality control records (Batch Records, Forms, Logbooks, etc.) Process/analytical method validation for clinical manufacturing Operation and maintenance of equipment in the GMP facility Preparation of products for shipment to other sites Drafting, reviewing and updating GMP documentation including SOPs Upkeep and maintenance of inventory in the GMP Facility Maintenance of the GMP facility including assisting with radioactive waste stream management Perform contamination wipe tests and surveys Performing and maintenance of the facilities' environmental monitoring program Leading manufacturing process and analytical method qualification activities Contribute to writing CMC sections for submission to regulatory agencies Maintain KPI and internal reports Supporting external tech transfer activities Required Skills Proficient with aseptic operations and environmental monitoring Proficient with QC methodologies (HPLC, GC, MS, Gamma Spec, etc.) Proficient with assembly and interpretation of analytical data Expertise with troubleshooting analytical and production equipment High attention to detail and organizational skills to enable working in a fast-paced environment Ability to work in an ISO7 environment with full gowning Adhere to stringent cleanroom protocols and maintain a high level of hygiene Perform precise aseptic manipulations in a restrictive environment Awareness of FDA and EU GMP requirements Ability to lift 60lbs Expertise with GMP radiopharmaceutical manufacturing and quality control Minimum, B.Sc. with 10+ years or M.Sc. with 7+ years of experience in the pharma industry or equivalent research experience Comprehensive knowledge of GMP manufacturing and quality control workflows Excellent verbal, written, and organizational skills Strong desire to be part of a mission‐oriented company leading transformative change for patients Proven demonstration of transparent communication and fostering open and diverse debate Ability to work with agility and manage ambiguity Personifies positive energy and exemplifies respect #J-18808-Ljbffr
    $136.8k-189.2k yearly 3d ago
  • Associate Principal Scientist, In Vitro Biology & CROs

    MSD Malaysia

    Senior scientist job in Boston, MA

    A global biotechnology company seeks an experienced Associate Principal Scientist to support in vitro pharmacology projects. The role involves collaborating with pharmacologists, managing CRO relationships, and assessing external resources for early drug discovery. The ideal candidate should possess a relevant Bachelor's degree and extensive industry experience. A hybrid work model is offered. Competitive salary range from $144,800 to $227,900 annually. #J-18808-Ljbffr
    $144.8k-227.9k yearly 3d ago
  • Senior Oncology MSL - Solid Tumor, Northeast

    Johnson & Johnson 4.7company rating

    Senior scientist job in Boston, MA

    A global healthcare company is hiring a Senior Medical Science Liaison for Solid Tumor Oncology in the Northeast. This role involves developing territory plans, engaging with KOLs, and addressing educational needs in the field. Candidates should have a doctorate and 2+ years of MSL experience, with a preference for oncology expertise. The position offers a competitive salary range, annual performance bonus, and a comprehensive benefits package including health insurance and retirement plans. #J-18808-Ljbffr
    $96k-115k yearly est. 4d ago
  • Principal AI/ML Scientist, Drug Discovery

    Scipro

    Senior scientist job in Cambridge, MA

    About the job: SciPro is partnered with a fast growing Scientific Data and AI platform startup who is searching for a Senior Applied AI/ML Engineer to join their team. They are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data across the scientific value chain and scientific vertices. They bring this AI data to life in a fast growing suite of universal lab data management solutions, scientific use cases, and AI-based scientific outcomes. Requirements: You will be a critical team member in a unique partnership to industrialize Scientific AI. As such, you will engage directly with customers onsite up to 4-5 days per week in the Boston region. Advanced degree in Biological, Data, or Computer Science Portfolio demonstrating end-to-end ownership of AI/ML products Proven track record of deploying AI models addressing real world problems Experience in biotech, biopharma, or pharma-adjacent projects Superior talent developing at least one of: ML-Reinforcement Learning, LLM/NLP, or Protein Design/Diffusion Models Responsibilities: Responsible for designing, developing, training, and validation of AI/ML products Support and advise executive leadership regarding technical and commercial feasibility Work with commercial teams to understand the impact of AI in life-sciences Collaborate with cross functional teams to build products Preferred Qualifications: Deep understanding of hurdles facing pharmaceutical drug development Demonstrated ability to make productized applications (for use by more than one group) Excellent communication skills Ability to advocate and evangelize for AI initiatives internally and externally Experience collaborating with teams on large software projects
    $92k-129k yearly est. 1d ago
  • Senior Research Scientist - Material Flammability, Fire Dynamics and Lithium-ion Battery Safety

    FM 3.9company rating

    Senior scientist job in Norwood, MA

    Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss. The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group. The position is responsible for all aspects of project management including project proposals, execution, and reporting. The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce. #FMG #LI-TA1
    $96k-131k yearly est. Auto-Apply 2d ago
  • Scientist I/II, Nucleic Acid Chemistry

    Alloy Therapeutics 3.8company rating

    Senior scientist job in Waltham, MA

    The Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team The Alloy Genetic Medicines group is innovating a novel RNA-based drug discovery platform, namely “AntiClastic”, spanning the fields of antisense therapeutics to immunomodulating therapeutics. This technology platform was launched by Alloy in 2023 after exclusively licensing its underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works closely with external partners to discover and develop AntiClastic RNA medicines. The Role This position reports to the Head of Nucleic Acid Chemistry. We are seeking a detail-oriented Nucleic Acid Chemistry Scientist to join our growing Nucleic Acid Chemistry team supporting the CMC development of oligonucleotides, mRNA, pDNA templates, and antibody-oligonucleotide conjugates (AOCs). The successful candidate will bring strong hands-on expertise in synthesis and purification of nucleic acids, as well as HPLC and LC-MS analytics for RNA, DNA, and nucleic acid medicines. You will have a proven track record of developing, documenting, qualifying, and troubleshooting analytical methods and production processes in a fast-paced industrial environment. This role also requires experience working with and managing Contract Research Organizations (CROs), and developing/synthesizing reference materials to enable method development and program progression. This role may be filled at Scientist I or Scientist II depending on experience and demonstrated level of independence. Principal Responsibilities Synthesis and Process Development pDNA Production: Execute microbial fermentation (E. coli) for plasmid DNA amplification; perform harvesting, lysis, and purification of pDNA. Linearization: Perform enzymatic restriction digests to linearize pDNA templates for downstream transcription. mRNA Synthesis: Lead in vitro transcription (IVT) reactions to produce mRNA, including enzymatic capping (Cap 1) and poly-adenylation. Oligonucleotide: Execute procedures to synthesize oligonucleotides. Purification: Utilize TFF (Tangential Flow Filtration) and chromatography (IEX, HIC, or Affinity) to purify intermediates and finished products from process-related impurities. Analytical Method Development & Qualification Develop, optimize, document, qualify, and transfer phase-appropriate analytical methods to support CMC activities for oligonucleotides, mRNA, pDNA, and AOCs. Design fit-for-purpose methods for identity, purity, integrity, potency/assay, and stability, including forced-degradation studies. Lead method qualification/verification activities for nucleic acid CQAs (e.g., product related purity, drug antibody ratios, mRNA capping efficiency, poly-A tail length, and residual template DNA). Execute and interpret analyses using HPLC/UPLC modalities (e.g., IPRP, AE, IEX, HILIC, SEC). Perform and interpret LC-MS analyses for intact oligos, mRNA mapping, sequence confirmation, impurity ID, and conjugate characterization. Independently troubleshoot instrument and method issues, ensuring data integrity and project continuity. Reference Materials Development Develop, qualify, and maintain analytical reference materials (e.g., standards, system suitability controls, impurity markers) to support method development, stability programs, and release testing. Coordinate and/or perform internal synthesis (chemical or enzymatic) of oligonucleotide and mRNA reference materials and related controls. CRO / External Partner Management Work effectively with and manage CRO/CDMO partners executing analytical studies, method development, or mRNA/pDNA manufacturing. Author, review, and approve CRO protocols, reports, data packages, and method documentation. Documentation & Data Integrity Document experiments in real time with excellent attention to detail in electronic lab notebooks. Support regulatory-compliant documentation for IND/BLA/MAA filings and respond to technical inquiries. Qualifications Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2-5 years of industry experience in nucleic acid synthesis or analytical development. Hands-on experience in pDNA, mRNA, and oligonucleotide production: Including microbial fermentation, pDNA purification, linearization, and in vitro transcription (IVT), solid-phase synthesis, & lyophilization. Extensive hands-on experience with HPLC/UPLC and LC-MS applied to mRNA, pDNA, oligonucleotides, and/or oligonucleotide conjugates. Demonstrated success developing and qualifying analytical methods for nucleic acids (e.g., Capillary Electrophoresis/Fragment Analyzer for mRNA integrity). Experience developing, synthesizing/sourcing, characterizing, and maintaining reference materials/standards. Proven experience working with and managing CRO and/or CDMO partners. Strong understanding of nucleic acid challenges (e.g., RNase-free handling, secondary structures, ion-pairing reagents, sequence variants, and conjugation heterogeneity). Experience with antibody-oligonucleotide conjugates (AOCs) and LNP-formulated mRNA. (Preferred) Familiarity with GMP/GLP environments and regulatory expectations for method lifecycle management. (Preferred) Hands-on knowledge of complementary techniques (e.g., qPCR/dd PCR, SEC-MALS, and biophysical assays). (Preferred) Taking Care of Our People We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together , we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one. Compensation Competitive base and equity compensation commensurate with level of experience and independence 401(k) company match Health & Family Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered Company-paid disability (STD, LTD) and life insurance Paid parental leave Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval) Unique Perks Unlimited PTO (paid time off) and flexible schedules Annual stipend for continuing education with commitment to your career through individualized professional development plan Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness Pay Transparency At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $126,000 - $144,000 with the final offer based on factors like your experience, skills, and alignment with our needs. Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team's professional and personal well-being. If you have any questions about pay or benefits, we're here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected] . We will make every effort to respond to your request for disability assistance as soon as possible.
    $126k-144k yearly Auto-Apply 20d ago
  • Scientist, Molecular AI Architecture

    SES 4.2company rating

    Senior scientist job in Boston, MA

    SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team is seeking an exceptional Scientist, Molecular AI Architecture to pioneer the convergence of biological computation, large-scale multimodal foundation models, and explainable AI architectures. This visionary role will drive next-generation materials discovery by developing novel AI systems. Essential Duties and Responsibilities: AI Architecture & Design: Architect novel AI systems and deep neural architectures (e.g., Transformers, CNNs) inspired by principles of systems neuroscience and neural coding principles. Design and implement large-scale multimodal foundation models and agentic AI systems capable of complex reasoning over molecular and battery datasets. Develop methods for model interpretability, representation engineering, and causal reasoning to ensure AI results are explainable and trustworthy for materials science. High-Performance Computing & Efficiency Lead software development efforts for high-performance computing (HPC), focusing heavily on GPU programming and scaling the training and inference efficiency of large neural networks. Optimize complex ML frameworks (like JAX) within systems and cluster computing environments (e.g., Singularity). Scientific ML Integration Create automated data-labeling and behavioral encoding models specifically designed to enhance Molecular AI training and data efficiency. Apply Scientific ML principles to complex molecular and battery datasets, translating biological computation concepts into practical AI solutions for materials discovery. Education and/or Experience: Education: Ph.D. in Computational and Systems Biology, Computational Neuroscience, or a closely related quantitative field. Core Expertise: Deep, demonstrated expertise in systems neuroscience, machine learning, and the design and implementation of deep neural architecture. HPC Software: Proven experience with software development for High-Performance Computing (HPC) environments, including expert-level GPU programming. Model Design: Practical experience in designing and training foundation models and working with concepts like multi-agent reasoning models. Interpretability Focus: Demonstrated work in model interpretability and representation engineering applied to complex scientific data. Preferred Qualifications: Specialized Frameworks: Practical experience with advanced mathematical and machine learning frameworks like JAX and Julia. Advanced Techniques: Expertise in Bayesian inference and working within specialized container/computing environments like Singularity. Advanced AI: Experience with the design and application of agentic AI systems and multimodal reasoning architectures.
    $70k-104k yearly est. Auto-Apply 60d+ ago
  • Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D

    Pharmaron 4.5company rating

    Senior scientist job in Coventry, RI

    Job Description Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D FLSA Status: Exempt Salary: $100,000-$160,0000 Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ****************** About the Role The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes. Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities. Key Responsibilities Perform hands-on small molecule process development and scale-up work. Use Design of Experiments (DoE) for process screening, optimization, and robustness studies. Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies. Apply process analytical technology (PAT) and process modeling. Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance. Conduct independent research to achieve mechanistic understanding for rational process design. Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction. Use process modeling tools to inform scale-up strategies. Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing. Drive cycle time reduction and process intensification initiatives. Implement innovative technologies such as continuous flow chemistry and automation platforms. Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments. Support development of complex transformations such as catalytic hydrogenation. Exhibit a mindset of safety and quality compliance. Collaborate cross-functionally within US, UK, and China-based teams. Required Experience & Skills Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense. Experience performing lab-based research/process development in a chemical engineering-related area. Experience with organic chemical synthesis and wet chemistry. Experience with small molecule pharmaceutical drug substance development. Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling. A high level of innovation, creativity, and self-initiative. Highly effective communication and collaboration skills. Good organizational, interpersonal, writing, and time management skills. Preferred Experience & Skills Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale. Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production. Demonstrated experience with chemical engineering-related technology development. Familiarity with kilo-scale laboratory equipment. Experience with process modeling (e.g., population balance modeling, distillation modeling). Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills). Why Pharmaron? Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
    $100k-160k yearly 9d ago
  • Medical Laboratory Scientist, Senior I - Immunology

    Massachusetts Eye and Ear Infirmary 4.4company rating

    Senior scientist job in Boston, MA

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Summary As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must: Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping. Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples. Adhere to quality control policies and document all QC activities, calibrations, and maintenance. Follow established corrective action procedures when test systems fall outside acceptable performance standards. Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director. Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities - The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. - Demonstrates advanced level of analytical skills and judgement. - Must have understanding of computer technology and its application to analytical procedures and quality control. - Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. - Must have the ability to work independently, evaluate situations and act appropriately. - Ability to multitask in a fast-paced environment. - Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. - Must be able to perform as a team member. - Excellent interpersonal skills. - Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. - Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical Requirements Standing Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $33.5-48.7 hourly Auto-Apply 50d ago
  • Scientist - Mass Spectrometry

    Eli Lilly and Company 4.6company rating

    Senior scientist job in Boston, MA

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. The LIGM RNA Group is seeking an experienced analytical scientist with extensive hands-on experience in analytical techniques for characterizing and analyzing small molecules, biologics, and/or oligonucleotides. The ideal candidate will have a proven track record in analytical method development and troubleshooting, as well as experience with liquid chromatography, (high resolution) mass spectrometry, and other advanced analytical techniques. They must possess strong technical problem-solving skills, be computer savvy with the ability to navigate multiple instrument control programs and data analysis environments, and be able to work independently to achieve efficient, quality results in a fast-paced environment. Responsibilities: Work closely with the chemistry team to source, explore, and implement the latest separation science and analytical technologies for the purification and characterization of oligonucleotides and their conjugates, including carbohydrates, lipids, peptides, and proteins. Conduct LC and LC-MS based method development for sensitive characterization of biologics including intact mass, reduced mass, peptide mapping, and glycan mapping to provide better understanding of attributes. Conduct semi-preparative and preparative method development activities to advance downstream processing for challenging modified oligonucleotides, utilizing RP purification, ion-exchange chromatography, spin filtration, TFF, FPLC, size exclusion chromatography, and MS-direct auto-scale preparative LC-MS techniques. Work with contractors and third-party vendors to troubleshoot and maintain lab instruments, including but not limited to UPLC, LC-MS, osmometer, and NanoDrop, ensuring they remain in peak operational condition. Learn new technologies quickly and apply effective scientific concepts and methods across multiple areas. Process and present data leveraging Microsoft Office apps, GraphPad and Spotfire for data organization and data visualization. Document experiments, data, technical reports, and findings electronically in an accessible manner with good documentation practices. Present findings, progress, and data proactively and regularly in group and department meetings. Possess a collaborative and willing-to-share mindset with excellent verbal and written communication skills, presentation skills, and attention to detail. Ability to follow Global Health, Safety & Environment Center (HSE) guidelines while performing tasks. Basic Qualifications: Bachelor's or Master's degree in Analytical Chemistry, Biochemistry, Chemistry, Food Science, or a related scientific field, with over 2 years of relevant post-graduate experience in industry. Additional Skills/Preferences: Strong analytical thinking skills with a demonstrated ability to articulate issues and extract and synthesize complex information into key focus areas. Extensive experience in operating and troubleshooting a range of mass spectrometers including Q-ToF, QQQ and Orbitrap Proficient with Thermo XCalibur, Agilent ChemStation and MassHunter software. Understanding tandem mass spectrometry and interpretation of MS/MS based characterization of including but not limited to peptide, peptide-oligonucleotide conjugates, and lipid conjugates. Extensive hands-on experience in downstream workflows for small molecules, biologics, and oligonucleotides. Experience with antibody-drug-conjugates (ADCs) or antibody-oligonucleotide-conjugates (AOCs) is a plus. Proven expertise in liquid chromatography including ion-pair reverse phase liquid chromatography as well as ion chromatography. Prior experience in native mass spectrometry and understanding of electrospray ionization as well as molecular behavior in the gas phase. Prior experience in proteomics, bioanalysis, and/or CMC is a significant advantage. Highly self-motivated and self-driven attitude with ability to own and drive projects into success. Strong organizational and communication skills and effective people skills. Capable of continuous learning, open-minded, highly organized, and detail oriented. Ability to balance multiple activities, prioritize and handle ambiguity. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly
    $71.3k-187k yearly Auto-Apply 60d+ ago
  • Cell Culture Scientist, Small Scale Production (Plainville, MA)

    Invitrogen Holdings

    Senior scientist job in Plainville, MA

    About the Role The Small-Scale Cell Culture Scientist is a hands-on technical contributor in the Bioprocess Design Center (BDC), responsible for designing, executing, and documenting upstream cell culture experiments that generate high-quality technical evidence for Thermo Fisher Scientific's single-use bioprocessing technologies. This role operates at the intersection of experimental biology and systems-level process design. The successful candidate will independently own small-scale cell culture studies, translate experimental outcomes into actionable insights, and support integrated workflow development across upstream unit operations. While primarily lab-focused, the role requires strong communication skills and comfort engaging with cross-functional partners and customers. Location: This is an onsite position in Plainville, Massachusetts. Residency within commuting distance is required. No relocation assistance will be provided. Key Responsibilities Experimental Design & Execution Independently design and execute small-scale upstream cell culture experiments (typically 2L-50L) using single-use bioreactor systems. Incorporate process analytical techniques (PAT), online sensors, and at-line/off-line analytics to monitor and assess cell culture performance. Execute mammalian cell culture processes such as fed-batch and intensified workflows, ensuring reproducibility, data integrity, and traceability. Troubleshoot experimental and data-related issues, including sensor performance, data quality, and process variability. Systems, Automation & PAT enablement Analyze experimental datasets using advanced data analytics approaches, including multivariate analysis, trend analysis, and statistical methods, as appropriate. Leverage JUMP™ and other analytical programs to support data-driven decision making and improve experimental efficiency. Translate complex datasets into clear, defensible conclusions and visual summaries suitable for internal and customer-facing audiences. Author protocols, technical reports, summaries, and SOPs that integrate experimental outcomes with process data insights. Data Analysis & Digital Enablement Analyze experimental datasets using advanced data analytics approaches, including multivariate analysis, trend analysis, and statistical methods, as appropriate. Leverage JUMP™ and other analytical programs to support data-driven decision making and improve experimental efficiency. Translate complex datasets into clear, defensible conclusions and visual summaries suitable for internal and customer-facing audiences. Author protocols, technical reports, summaries, and SOPs that integrate experimental outcomes with process data insights. Collaboration & Communication Collaborate closely with engineers, scientists, and cross-functional teams to align experimental work with BDC priorities. Support customer visits, technical demonstrations, and internal reviews by clearly explaining experimental intent and results. Communicate progress, risks, and outcomes effectively to technical and non-technical audiences. Laboratory Operations & Compliance Maintain a safe, compliant, and organized laboratory environment. Follow applicable safety, quality, and data integrity requirements. Contribute to continuous improvement of lab workflows and experimental practices. Qualifications Education B.S. in Chemical Engineering, Biochemical Engineering, Biotechnology, Bioengineering, or a related field with 3+ years of relevant experience M.S. with 2+ years of relevant experience Equivalent combinations of education and experience will be considered Experience & Skills Hands-on experience with mammalian cell culture and upstream bioprocessing Familiarity with single-use bioreactor systems and small-scale process development Experience designing and executing controlled experiments; DOE experience preferred Strong data analysis, documentation, and technical writing skills Working knowledge of GLP/GMP concepts and laboratory best practices Proficiency with standard data analysis and reporting tools (e.g., Excel, PowerPoint) Preferred Attributes Demonstrated ability to work independently in a fast-paced, matrixed environment Strong problem-solving skills and attention to detail Ability to translate experimental data into practical insights Comfortable operating in environments with evolving requirements and priorities Collaborative mindset with a customer-centric orientation Physical Requirements Ability to work in a laboratory environment and handle light to moderate lifting (up to ~50 lbs) Standing and walking for extended periods during experimental execution Manual dexterity to operate laboratory equipment and instrumentation Why Join the Bioprocess Design Center The BDC is where Thermo Fisher technologies are stress-tested, validated, and transformed into real-world solutions for our customers. This role offers the opportunity to work hands-on with cutting-edge single-use systems, contribute to evidence that shapes customer confidence, and grow within a technically rigorous, highly collaborative environment. Compensation and Benefits The salary range estimated for this position based in Massachusetts is $96,000.00-$127,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: A choice of national medical and dental plans, and a national vision plan, including health incentive programs Employee assistance and family support programs, including commuter benefits and tuition reimbursement At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: *****************************************************
    $96k-127k yearly Auto-Apply 8d ago
  • Toxicologist

    Watton Hall

    Senior scientist job in Cambridge, MA

    Title: Toxicologist The Toxicologist will play a critical role in the assessment of the safety profile of small molecule drug candidates throughout the drug development process. This position requires a deep understanding of toxicological principles, regulatory requirements, and the ability to interpret complex data to inform decision-making. Responsibilities Conduct comprehensive toxicological evaluations of small molecules Analyze data from non-clinical studies to identify potential safety concerns and recommend strategies for risk mitigation. Prepare toxicology sections for regulatory submissions (INDs, NDAs) in accordance with FDA, EMA, and ICH guidelines. This will include liaising with the regulatory agencies related to toxicological data. Participate in project teams to provide expert advice on safety-related issues throughout the product lifecycle. Conduct risk assessments based on toxicological data to support decision-making processes regarding compound progression Profile Ph.D. or equivalent degree in Toxicology, Pharmacology, or a related field Mulitple years experience in the pharmaceutical or biotechnology industry. Small molecules experience Strong knowledge of GLP regulations, ICH guidelines, and FDA/EMA submission requirements. Experience working directly with regulatory agencies is an advantage. Benefits: Competitive salary with performance-based bonuses and comprehensive benefits package Home office option Excellent company culture
    $60k-101k yearly est. 60d+ ago
  • Senior Medical Laboratory Scientist - Microbiology, Evening

    Mass General Brigham

    Senior scientist job in Boston, MA

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Senior Medical Lab Scientist, Microbiology 3 PM to 11:30 PM Summary As required by CLIA, the testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests that are authorized by the laboratory director and require a degree of skill commensurate with the individual's education, training, experience, and technical abilities. Works independently in an efficient and organized manner to ensure accurate results and records. The work requires a professional level of knowledge to accurately read and interpret test results used by providers in the diagnosis and treatment of diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for the technical oversight of the laboratory, including day-to-day supervision or oversight of laboratory operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I is responsible for supervision of assigned workstations, including Quality Control (QC) review, training, competency assessment of staff, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all instruments/methods applicable to their role: • Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and maintaining records of patient test results. • Maintain records that demonstrate that proficiency testing samples are tested in the same manner as patient samples. • Adhere to the laboratory's quality control policies; document all quality control activities, instrument and procedural calibrations, and maintenance performed. • Follow the laboratory's established corrective action policies and procedures whenever test systems are not within the laboratory's established acceptable levels of performance. • Be capable of identifying problems that may adversely affect test performance or reporting of test results, and either correct the problems or immediately notify the general supervisor, technical consultant, technical supervisor, clinical consultant, or director. • Document all corrective actions taken when test systems deviate from the laboratory's established performance specifications. (42 CFR 493.*************** Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 3-5 years required Knowledge, Skills and Abilities - The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. - Demonstrates advanced level of analytical skills and judgement. - Must have understanding of computer technology and its application to analytical procedures and quality control. - Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. - Must have the ability to work independently, evaluate situations and act appropriately. - Ability to multitask in a fast-paced environment. - Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. - Must be able to perform as a team member. - Excellent interpersonal skills. - Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. - Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical Requirements Standing Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 75 Francis Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Evening (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $33.5-48.7 hourly Auto-Apply 55d ago
  • Senior Medical Laboratory Scientist - Chemistry

    Brigham and Women's Hospital 4.6company rating

    Senior scientist job in Boston, MA

    Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Medical Laboratory Scientist, Senior I - Chemistry Day Shift 7 AM to 3:30 PM As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director that require a degree of skill appropriate to their education, training, experience, and technical abilities. They work independently in an efficient and organized manner to ensure accurate results and records. The role requires professional knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for the technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I oversees assigned workstations, including Quality Control (QC) review, training, competency assessment of staff, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods: Follow the laboratory's procedures for specimen handling, processing, test analyses, reporting, and maintaining patient test result records. Maintain records demonstrating that proficiency testing samples are tested in the same manner as patient samples. Adhere to the laboratory's quality control policies and document all quality control activities, instrument and procedural calibrations, and maintenance. Follow established corrective action policies and procedures whenever test systems are not within acceptable performance levels. Identify problems that may affect test performance or result reporting and either correct them or immediately notify the appropriate supervisor, consultant, or director. Document all corrective actions taken when test systems deviate from established performance specifications (42 CFR 493.***************. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities * The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. * Demonstrates advanced level of analytical skills and judgement. * Must have understanding of computer technology and its application to analytical procedures and quality control. * Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. * Must have the ability to work independently, evaluate situations and act appropriately. * Ability to multitask in a fast-paced environment. * Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. * Must be able to perform as a team member. * Excellent interpersonal skills. * Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. * Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical RequirementsStanding Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 90 Blossom Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $33.5-48.7 hourly Auto-Apply 4d ago
  • ADME-PK Principal Scientist, Preclinical Development

    Dyne Tx

    Senior scientist job in Waltham, MA

    A biotechnology company in Waltham, MA is seeking a Principal Scientist in ADME-PK to enhance drug delivery to muscle and CNS tissues. The successful candidate will design preclinical studies, author regulatory documents, and collaborate across various teams. Candidates should possess a PhD in a relevant field and over 6 years of industry experience, with expertise in pharmacokinetics and drug metabolism. This role offers a competitive salary in the range of $159,000 to $195,000 USD depending on experience. #J-18808-Ljbffr
    $159k-195k yearly 3d ago
  • Lead Scientist, Pharma R&D & AI-Driven Drug Discovery

    Victrays

    Senior scientist job in Boston, MA

    A leading healthcare technology firm in Boston seeks an Associate Principal Scientist to advance drug R&D through computational research. The ideal candidate will leverage the Tempus platform to analyze diverse datasets, ensuring actionable insights for clients. This role requires a Masters or Ph.D. in areas like Bioinformatics or Data Science, proficiency in R or Python, and comfort in client interactions. A competitive salary range of $170,000-$230,000 reflects the expertise required for this role, alongside comprehensive benefits. #J-18808-Ljbffr
    $170k-230k yearly 1d ago
  • Senior Principal Scientist, GMP Radiopharmaceuticals

    The University of Texas Md Anderson Cancer Center 4.3company rating

    Senior scientist job in Boston, MA

    A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr
    $98k-137k yearly est. 3d ago
  • Translational PET Imaging Scientist - Clinical Trials Lead

    MSD Malaysia

    Senior scientist job in Boston, MA

    A prominent pharmaceutical company is seeking a Translational PET Imaging Scientist to lead clinical implementation of novel PET tracers in oncology studies. Responsibilities include developing imaging strategies, overseeing studies, and managing regulatory submissions. The ideal candidate should hold a Ph.D. and have extensive experience in advancing PET tracers into clinical trials with proven project leadership. This role offers a hybrid work model and a competitive salary range. #J-18808-Ljbffr
    $65k-101k yearly est. 5d ago

Learn more about senior scientist jobs

How much does a senior scientist earn in Cranston, RI?

The average senior scientist in Cranston, RI earns between $75,000 and $139,000 annually. This compares to the national average senior scientist range of $74,000 to $153,000.

Average senior scientist salary in Cranston, RI

$102,000

What are the biggest employers of Senior Scientists in Cranston, RI?

The biggest employers of Senior Scientists in Cranston, RI are:
  1. Oracle
  2. Pacific Northwest National Laboratory
  3. Cardinal Health
  4. Cisco
  5. CVS Health
  6. RGA Environmental, A Terracon Company
  7. Connexion Systems + Engineering
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