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Senior Principal Scientist jobs at Frontier Medicines

- 567 jobs
  • Principal Scientist, Computational Chemistry

    Frontier Medicines 4.1company rating

    Senior principal scientist job at Frontier Medicines

    Job Description Frontier Medicines is seeking a highly motivated individual to fill the position of Principal Scientist, Computational Chemistry. The successful candidate will play a leading role in developing medicinal chemistry optimization strategies for key drug discovery programs. This individual will review experimental results, develop SAR hypotheses for activity, selectivity, and properties, and make design suggestions to improve the profiles of small molecule drug candidates. As a covalent drug discovery-focused company, there is the opportunity for method development within this evolving field, in addition to applying the full range of ligand-based and structure-based design approaches and leveraging data from chemoproteomics, AI and quantum mechanics. This role is key to Frontier Medicines' success and an opportunity to work in a highly collaborative and energetic environment with short communication lines across functions and departments, and regular interactions with senior leaders. As the senior computational chemist, there is furthermore an opportunity to build out the computational team in the future Requirements What will you be doing? Design, execute, and analyze computational chemistry studies using a wide range of ligand-based, structure-based, and physics-based modeling techniques. Partner closely with medicinal chemists and biologists to develop and refine structure-activity relationships (SAR), optimize molecular properties, and guide design hypotheses. Contribute to project strategy and decision-making across all discovery stages, including target assessment, hit identification, lead optimization, and development candidate nomination. Champion innovative computational tools and workflows, identify and implement emerging technologies that enhance Frontier's CADD capabilities - specifically with an eye to the applicability to the covalent domain. Work closely and partner with the AI team to develop and integrate novel AI applications into daily drug design workflows Communicate scientific results, design rationales, and strategic insights to multidisciplinary teams and senior leadership. What are we looking for? Ph.D. in Computational/Theoretical Chemistry, Biophysics, or a related discipline with 5+ years of relevant industry experience in drug discovery (biotech or pharma). Demonstrated expertise in applying computational chemistry to small molecule design and optimization. Strong experience with leading computational chemistry tools, CCG tools including MOE is highly preferred Basic knowledge of scripting and programming with Python preferred Experience with quantum mechanics (QM) is highly preferred Proven track record of scientific impact, as evidenced by publications, patents, and successful project contributions. Solid understanding of medicinal chemistry principles, SAR analysis, and ADMET optimization. Excellent communication, presentation, and cross-functional collaboration skills. Ability to operate independently and as a scientific leader in a fast-paced, startup environment. Legally authorized to work in the U.S. Benefits Health Care Plan (Medical, Dental & Vision) Retirement Plan (401k, IRA) Life Insurance (Basic, Voluntary & AD&D) Paid Time Off (Vacation, Sick & Public Holidays) Family Leave (Maternity, Paternity) Short Term & Long Term Disability Training & Development Free Food & Snacks Wellness Resources Stock Option Plan At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $175,000 - $231,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits. This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.
    $175k-231k yearly 25d ago
  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    Modesto, CA jobs

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    Fresno, CA jobs

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    Sacramento, CA jobs

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Heart Institute - Cingolani Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and specialized care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. Join our team and use your skill with an organization known nationally for excellence in research! Are you ready to be a part of breakthrough research? Working independently but in close cooperation and in consultation with the Dr. Cingolani and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Primary Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the PI. Analyzes, interprets, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to the research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within the area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis, operation and maintenance of specialized equipment. Excellent written and oral communication skills are essential. Knowledge of safety standards. Req ID : 2459 Working Title : Postdoctoral Scientist - Heart Institute - Cingolani Lab Department : Heart Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400 - $93,600
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist, Turkson Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    We are seeking a highly motivated postdoctoral scientist (1-2 years of experience following terminal degree) to join an NIH/NCI-funded drug discovery laboratory. The ideal candidate has strong expertise in the design and synthesis of small molecules, along with classical structure determination using modern spectroscopic methods (¹H, ¹³C, ¹⁹F NMR) and mass spectrometry (MS). You will bring fresh energy and ideas to ongoing discovery efforts and actively contribute to the research program. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Key Responsibilities Design, synthesize, purify, and characterize small-molecule compounds. Perform structure elucidation using ¹H/¹³C/¹⁹F NMR and MS; maintain meticulous experimental records. Propose hypotheses, plan experiments, and interpret data to drive hit-to-lead optimization. Author independent reports, manuscripts, and presentations; contribute to grant/research proposals. Collaborate effectively with PI, staff scientists, students, and research assistants; help mentor junior team members. Proactively identify technical challenges and propose innovative solutions. Primary Duties and Responsibilities May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Requirements: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. Desirable Qualifications Experience in small-molecule synthesis and/or natural products' synthesis. Experience in anticancer drug discovery research. Demonstrated ability in organic synthesis. Demonstrated ability to generate independent reports, publications, and ideas. Demonstrated ability to interact effectively with laboratory members, including students and/or assistants. To Apply This position is available immediately. Please email a single PDF (or a consolidated set of documents) including: Cover letter describing how you meet the minimum and desirable qualifications and outlining your research interests and career goals Current curriculum vitae (CV) 3 references with contact information (including email addresses) Send materials to: James Turkson, Ph.D. - ********************** Req ID : 12290 Working Title : Postdoctoral Scientist, Turkson Lab Department : Cancer Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $30.00 - $45.00
    $30-45 hourly 1d ago
  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    San Diego, CA jobs

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Microbiology - Jorth Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    The Jorth Lab studies host-pathogen interactions of antibiotic-resistant bacteria. We are looking to add a postdoctoral fellow to investigate molecular mechanisms of antibiotic resistance and bacterial pathogenesis, as well as potential therapeutic targets for these hard-to-treat infections. Experience with bacterial genetics, infection models, and computational biology are desirable. The Postdoctoral Scientist will be expected to work independently but in close cooperation and in consultation with the Principal Investigator. The Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. The Postdoctoral Scientist will design and conduct experiments, analyzes and interpret data, and participate in writing publications and giving presentations as author or co-author. May assist in preparation of grant proposals. Not responsible for generating grant funds. Primary Duties and Responsibilities May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator May develop, adapt, and implement new research techniques and protocols. Analyzes interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Education: Doctorate Degree in area directly related to field of research specialization is required. Experience and Skills: Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment Req ID : 12690 Working Title : Postdoctoral Scientist - Microbiology - Jorth Lab Department : Academic Pathology Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400 - $93,600
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Heart Institute - Makkar Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and niche care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. Are you ready to be a part of breakthrough research? Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Primary Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes, interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Education: Doctorate Degree in area directly related to field of research specialization is required. Experience and Skills: No experience required. Acquires thorough technical and theoretical knowledge of research project and objectives during a one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. Req ID : 13433 Working Title : Postdoctoral Scientist - Heart Institute - Makkar Lab Department : Heart Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400 - $93,600
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Stripp/Yao Labs - Department of Medicine

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Are you looking to contribute to groundbreaking research? We invite you to consider this great career opportunity! Cedars-Sinai is an international leader in biomedical research, we translate discoveries into successful treatments with global impact. Principal Investigators, Dr. Barry Stripp, PhD and Dr. Changfu Yao, PhD are looking for a Postdoctoral Scientist to join their research labs! The Stripp and Yao laboratories constitute the Lung Regeneration group at Cedars-Sinai Medical Center and seek to understand basic mechanisms of lung maintenance, how this is disrupted in disease and to develop regenerative medicine approaches that will restore structure and function to damaged lung tissue. The laboratories couple the genetic tractability of mouse models with studies using human lung tissue to identify stem/progenitor cells and to understand how they are regulated under normal or injured/diseased states. The long-term goal is to exploit this newly acquired knowledge to improve the care of patients with lung disease. About the Role Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex procedures throughout training period. The incumbent may develop, adapt, and implement new research techniques and protocols. The team member analyzes and interprets data, may assist in preparation of grant proposals, and participates in publications and presentations as author or co-author. This position is not responsible for generating grant funds. Primary Duties and Responsibilities: Designs and performs experiments. Will keep appropriate experimental records and documentation, and analyze the results with the Principal Investigator. Analyzes, interprets, summarizes, and compiles data. Operates and maintains equipment and instruments. May prepare and submit NIH-F31 application or similar fellowship to non-federal agencies. Qualifications Education Requirements: Doctorate degree (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. Experience: Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Acquires complete technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Demonstrated ability to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. #LI-On-site #Jobs-Indeed About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 8511 Working Title : Postdoctoral Scientist - Stripp/Yao Labs - Department of Medicine Department : Research - Pulmonary Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400 - $93,600
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist, Zheng Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. To learn more about Dr. Zheng's work, please visit Dr. Bin Zheng's profile here - ********************************************** Primary Duties and Responsibilities May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications This Postdoctoral Scientist role is designed as a training opportunity for those who have recently completed their PhD or doctoral degree. To ensure we provide the intended mentorship and career development, we are looking for candidates who are within five years of completing their doctorate. If you're within this timeframe and excited about advancing your research in a supportive and collaborative environment, we encourage you to apply! Requirements: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. 1 year, acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Req ID : 12423 Working Title : Postdoctoral Scientist, Zheng Lab Department : Research - Hematology and Cellular Therapy Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $30.00 - $45.00
    $30-45 hourly 1d ago
  • Postdoctoral Scientist - Heart Institute - Rogers Lab

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and niche care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. Are you ready to be a part of breakthrough research? The Rogers Laboratory focuses on cell therapy and regenerative medicine. Research conducted in the Rogers Lab stems largely from the pioneering work of Eduardo Marbán, MD, PhD, who mentored Dr. Rogers as a postdoctoral scholar. The Marbán Lab was first to isolate and characterize cardiosphere-derived cells (CDCs), a type of heart progenitor/stromal cell now in advanced clinical trials. Initial studies documented the reparative benefits of CDCs when delivered directly into dystrophic hearts. Subsequent research showed CDCs to be effective in dystrophic hearts and skeletal muscle when delivered intravenously - a clinically preferable method. This work motivated a Phase II (HOPE-2) and Phase III (HOPE-3) clinical trial to repeatedly deliver allogeneic CDCs intravenously to human patients with advanced-stage Duchenne muscular dystrophy. To learn more, please visit Rogers Lab at Cedars-Sinai. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Primary Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes, interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Education: Doctorate Degree in area directly related to field of research specialization is required. Experience and Skills: No experience required. Acquires thorough technical and theoretical knowledge of research project and objectives during a one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 9625 Working Title : Postdoctoral Scientist - Heart Institute - Rogers Lab Department : Heart Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Guerin Children's - Khokha Lab (Full-Time, On-Site)

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Principal Investigator, Dr. Mustafa Khokha, MD, is looking for a Research Associate III to join the team! The Khokha Lab uses Xenopus, a frog model, to understand the molecular mechanisms that drive birth defects. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. What are the Primary Duties and Responsibilities? May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Design and perform experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyze interpret, summarize, and compile data. Perform routine and complex laboratory procedures throughout the training period. Operate and maintain equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Educational & Experience Requirements: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required No experience required. Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Previous experience with basic science / animal laboratory research, including xenopus, other aquatic animal, or mouse models strongly preferred. Previous training in genomics/genetics preferred. Experience with IACUC animal protocols preferred. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 10513 Working Title : Postdoctoral Scientist - Guerin Children's - Khokha Lab (Full-Time, On-Site) Department : Research - Childrens Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Bonda Lab - Department of Neurosurgery

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Are you a hardworking and dedicated research professional interested in being part of breakthrough Research? When you join Cedars-Sinai, you become part of a team that is at the forefront of medical advancements and life-saving medical and scientific breakthroughs. Cedars-Sinai is one of the leading institutes for driven research funding from the National Institutes of Health. If you're ready to be a part of breakthrough research, then we invite you to consider this exciting opportunity and apply today! Principal Investigator, David Bonda, MD, is seeking a Postdoctoral Scientist to join the team! The Bonda Lab is investigating the single neuron and network-level dynamics governing volitional control over reflexive and higher order behavior. About the Role Under the mentorship of Dr. David Bonda (********************************************************************************* in the department of neurosurgery and the Center for Neural Science and Medicine (***************************************************************** the Postdoctoral Scientist will be engaged in ground breaking research with the goal of developing a mechanistic understanding of human cognition. The Postdoctoral Scholar will closely with other postdoctoral scholars, graduate students, undergraduate students, research associates, and collaborators to achieve this goal. The Postdoctoral Scientist will participate in systems neuroscience research throughout the training period by applying intracranial recordings in humans and advanced computational and analysis methods to study the mechanisms of learning, memory, and decision making. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. This NIH and NSF funded position is an outstanding opportunity to receive training in a pioneering research program. Primary Duties and Responsibilities: Keeps appropriate experimental records and documentation and analyzes the results with the Principal Investigator. Operates and maintains equipment and instruments. May design and perform experiments. Analyzes, interprets, summarizes, and compiles data. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Department-Specific Information: Designs and performs human intracranial electrophysiology experiments. Designs, implements, and uses computational techniques to process and analyze electrophysiological and behavioral data. Uses a programming language (MATLAB and Python) to implement analysis procedures and analyzes and interprets the results. Uses, develop and extend complex data analysis programs to develop biological insights from complex electrophysiological datasets. Develops, implement, and continuously improve behavioral experiments. Interact respectfully and efficiently with patients, caregivers, and hospital clinical staff. Qualifications Education: Doctorate degree in area directly related to field of research specialization. Recent graduates with a Ph.D degree in Neuroscience (or a related field) is strongly preferred. Experience and Skills: Works independently on research projects developed together with the mentor within area of specialization. Acquires technical and theoretical knowledge of research project and objectives during one to five (1-5) years post-doctoral appointment. Strong computational, programming (Matlab and Python), data analysis, statistics and electrophysiology skills are essential. Knowledge of the cognitive neuroscience literature is essential. Previous experience with human scalp-or intracranial EEG or animal intracranial electrophysiology is preferred. Proven track record to conduct high-quality research evidenced by first author publications is required. #Jobs-Indeed #LI-Onsite About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 12100 Working Title : Postdoctoral Scientist - Bonda Lab - Department of Neurosurgery Department : Neurosurgical MS Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Guerin Children's - Klein Lab (Full-Time)

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Join Dr. Ophir Klein and his team as a Postdoctoral Scientist in Guerin Children's! The Klein Laboratory is seeking a Postdoctoral Scientist to join the team and assist in new and ongoing research initiatives, to provide specialized support for lab experiments, and to foster ongoing research education within Guerin Children's. ****************************************************** Are you ready to be a part of breakthrough research? Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Primary Duties and Responsibilities May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Educational Requirements: Doctorate Degree (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required. Experience & Skills Requirements: No experience required. Acquires through technical and theoretical knowledge of research projects and objectives during one (1) to five (5) years of post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. Work Location: Please note: This is a fully on-site position that requires travel between Klein Lab locations in Los Angeles, CA, and San Francisco, CA. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 10667 Working Title : Postdoctoral Scientist - Guerin Children's - Klein Lab (Full-Time) Department : Childrens Health Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Guerin Children's - Khokha Lab - Full-Time, On-Site

    Cedars-Sinai 4.8company rating

    Beverly Hills, CA jobs

    Principal Investigator, Dr. Mustafa Khokha, MD, is looking for a Postdoctoral Scientist to join the team in Spring 2026! The Khokha Lab uses Xenopus, a frog model, to understand the molecular mechanisms that drive birth defects. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. What are the Primary Duties and Responsibilities? May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Design and perform experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyze interpret, summarize, and compile data. Perform routine and complex laboratory procedures throughout the training period. Operate and maintain equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Educational & Experience Requirements: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Previous experience with basic science / animal laboratory research, including xenopus, other aquatic animal, or mouse models strongly preferred. Previous training in genomics/genetics preferred. Experience with IACUC animal protocols preferred. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 12099 Working Title : Postdoctoral Scientist - Guerin Children's - Khokha Lab - Full-Time, On-Site Department : Research - Childrens Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Guerin Children's - Pediatric Regenerative Medicine - L. Gao Lab (Full-Time, On-Site)

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Principal Investigator, Dr. Longfei Gao, PhD, is looking for a Postdoctoral Scientist to join the team! The Gao Lab investigates the biology of hematopoietic stem cells (HSCs) and their niches under normal and diseased conditions, with a particular focus on how the niche within and beyond the bone marrow regulates HSC behavior. Learn more about the Gao Lab. Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. What are the Primary Duties and Responsibilities? May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Design and perform experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyze interpret, summarize, and compile data. Perform routine and complex laboratory procedures throughout the training period. Operate and maintain equipment and instruments. May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Qualifications Educational & Experience Requirements: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Experience in mouse genetic, lineage tracing, or flow cytometry strongly preferred. Familiar with microscopy techniques, single-cell sequencing, and related data analysis preferred. Record of research productivity desired. Highly motivated and able to work independently and as part of a team. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 12501 Working Title : Postdoctoral Scientist - Guerin Children's - Pediatric Regenerative Medicine - L. Gao Lab (Full-Time, On-Site) Department : Childrens Health Institute Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 1d ago
  • Postdoctoral Scientist - Tourtellotte Lab - Neurodegeneration and Neurodevelopment

    Cedars-Sinai 4.8company rating

    Los Angeles, CA jobs

    Principal Investigator, Dr. Warren G. Tourtellotte is looking for a Postdoctoral Scientist to join the team! A Postdoctoral Scientist position is immediately available to work on projects related to microglia in neurodegeneration or in projects related to growth factor and tyrosine kinase receptor signaling. The Tourtellotte Lab studies the role of microglia immune function in neurodegenerative diseases, such as Alzheimer's Disease (Gomez et al., Nat. Aging, 5(7): 1280), and the role of growth factor signaling in peripheral neuropathy and tyrosine kinase receptor signaling (Li et al., J. Clin. Invest., 130(5):2478; Gosh and Tourtellotte, Ann. Rev. Pathology, 16:487; Jackson et al., Development 141(12):2452). Depending on the relevant expertise and specific interests, the successful candidate will be a leader of an independent research project but can contribute to all projects in the lab with co-authorship on manuscripts. Working independently, but in close cooperation and consultation with the Principal Investigator (PI) and other Research Scientists in the lab, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout the training period. The candidate will be expected to design and conduct experiments, collect and analyze data, troubleshoot experiments, analyze data for publication and grant applications, present research at national and international meetings, and prepare manuscripts for publication. Teaching other research staff, students and clinical residents may be required. With support from the PI and as the candidate progresses in their training, they will be expected to compete for research funding that will appropriately support their independent career development. Are you ready to be a part of breakthrough research? Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. Primary Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. May develop, adapt, and implement new research techniques and protocols. Analyzes interpret, summarizes, and compiles data. Performs routine and complex laboratory procedures throughout the training period. Operates and maintains equipment and instruments. Education: Doctorate Degree in area directly related to field of research specialization is required. Experience and Skills: Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. Qualifications Education: Doctorate Degree in area directly related to field of research specialization is required. Experience and Skills: Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 12205 Working Title : Postdoctoral Scientist - Tourtellotte Lab - Neurodegeneration and Neurodevelopment Department : Academic Pathology Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400 - $93,600
    $62.4k-93.6k yearly 1d ago
  • Principal Scientist, Computational Chemistry

    Frontier Medicines 4.1company rating

    Senior principal scientist job at Frontier Medicines

    Frontier Medicines is seeking a highly motivated individual to fill the position of Principal Scientist, Computational Chemistry. The successful candidate will play a leading role in developing medicinal chemistry optimization strategies for key drug discovery programs. This individual will review experimental results, develop SAR hypotheses for activity, selectivity, and properties, and make design suggestions to improve the profiles of small molecule drug candidates. As a covalent drug discovery-focused company, there is the opportunity for method development within this evolving field, in addition to applying the full range of ligand-based and structure-based design approaches and leveraging data from chemoproteomics, AI and quantum mechanics. This role is key to Frontier Medicines' success and an opportunity to work in a highly collaborative and energetic environment with short communication lines across functions and departments, and regular interactions with senior leaders. As the senior computational chemist, there is furthermore an opportunity to build out the computational team in the future Requirements What will you be doing? Design, execute, and analyze computational chemistry studies using a wide range of ligand-based, structure-based, and physics-based modeling techniques. Partner closely with medicinal chemists and biologists to develop and refine structure-activity relationships (SAR), optimize molecular properties, and guide design hypotheses. Contribute to project strategy and decision-making across all discovery stages, including target assessment, hit identification, lead optimization, and development candidate nomination. Champion innovative computational tools and workflows, identify and implement emerging technologies that enhance Frontier's CADD capabilities - specifically with an eye to the applicability to the covalent domain. Work closely and partner with the AI team to develop and integrate novel AI applications into daily drug design workflows Communicate scientific results, design rationales, and strategic insights to multidisciplinary teams and senior leadership. What are we looking for? Ph.D. in Computational/Theoretical Chemistry, Biophysics, or a related discipline with 5+ years of relevant industry experience in drug discovery (biotech or pharma). Demonstrated expertise in applying computational chemistry to small molecule design and optimization. Strong experience with leading computational chemistry tools, CCG tools including MOE is highly preferred Basic knowledge of scripting and programming with Python preferred Experience with quantum mechanics (QM) is highly preferred Proven track record of scientific impact, as evidenced by publications, patents, and successful project contributions. Solid understanding of medicinal chemistry principles, SAR analysis, and ADMET optimization. Excellent communication, presentation, and cross-functional collaboration skills. Ability to operate independently and as a scientific leader in a fast-paced, startup environment. Legally authorized to work in the U.S. Benefits Health Care Plan (Medical, Dental & Vision) Retirement Plan (401k, IRA) Life Insurance (Basic, Voluntary & AD&D) Paid Time Off (Vacation, Sick & Public Holidays) Family Leave (Maternity, Paternity) Short Term & Long Term Disability Training & Development Free Food & Snacks Wellness Resources Stock Option Plan At Frontier, we strive to build a diverse and equitable workplace. The salary range for this role is $175,000 - $231,000. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits. This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.
    $175k-231k yearly Auto-Apply 55d ago

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