Doctoral Fellow jobs at Univ. Of Texas Cancer Ctr. - 95 jobs

Postdoctoral positions are available to study molecular mechanisms associated with therapeutic response and resistance to RAS inhibition in non-small cell lung cancer (NSCLC) in the laboratory of Ferdinandos Skoulidis, MD, PhD, at the University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested in understanding the molecular diversity of KRAS-mutant NSCLC and developing rational and tailored treatment strategies for patients bearing KRAS-mutant lung tumors. We utilize a multifaceted approach that encompasses preclinical studies in immunocompetent syngeneic and genetically engineered co-mutational models of KRAS-mutant NSCLC as well as PDX/CDXs, in vitro models, and large collections of well-annotated clinical specimens. We employ state-of-the-art computational biology/bioinformatics approaches to dissect acute and adaptive responses to RAS inhibition in vitro and in vivo. We are committed to a question-driven approach that seeks to address the most urgent clinically relevant scientific questions. Applicants with experience in any of these areas and a true passion for cutting-edge bench-to-bedside research are encouraged to apply and provide three professional references. LEARNING OBJECTIVES Trainees will perform basic and translational research involving molecular biology approaches (such as CRISPR/Cas technology, Western blotting, ELISA, immunohistochemistry), in vitro assays (such as drug screening, flow cytometry, development of resistant cell lines) and in vivo experiments using xenograft, syngeneic and genetically engineered mouse models of KRAS-mutant lung cancer. Candidates with prior experience in computational biology will acquire additional skills and be involved in the analysis of single-cell RNA Sequencing, WES, and in situ transcriptomics data. Trainees will present their findings at regular lab meetings, departmental seminars, and national conferences. Trainees will submit their findings for publication in a peer-reviewed scientific journal. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS Applications are invited from qualified individuals interested in working in a translational research lab, with a PhD and/or MD. The ideal candidate(s) should have less than 2 years of prior postdoctoral experience and have a background in cancer or cell and molecular biology. Experience in RAS signaling and targeting, and studies involving mouse models of KRAS-driven cancers, is preferred. We are also looking for applicants with prior expertise in computational biology and bioinformatics, including analysis of single-cell RNA sequencing data and in situ transcriptomics. Candidates should be innovative thinkers and highly motivated to pursue an independent career in biomedical research. Job Knowledge And Skills: 1. Enthusiastic, highly self-motivated candidate with the ability to think and function independently 2. A strong background in cancer biology or cell and molecular biology. Prior experience in RAS signaling and/or targeting is preferred 3. Expertise in computational biology/bioinformatics (including proficiency in Python/R) would be desirable, though this skill is not essential 4. Prior experience with studies involving mice, including both xenograft/syngeneic models and genetically engineered mice, is preferred 5. Dedication to basic research, a true "drive", is important 6. Collegial nature and ability to work well as part of a team 7. Excellent command of written and spoken English language 8. Prior publication record with at least one published manuscript as first author ADDITIONAL APPLICATION INFORMATION ****************************************************************** POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

We are inviting motivated candidates to apply for an immediately open post-doctoral scholar position in the Department of Health Disparities Research, the University of Texas MD Anderson Cancer Center (MDACC) in Houston. We seek candidates with a track record of peer-reviewed publications, training in psychology, public health, communication, or other behavioral science, and strong work ethics and commitment to research. Our team has expertise in applying psychosocial research to improve the well-being of cancer survivors and to enhance cancer preventive health behaviors among underserved populations. We are conducting several large NIH funded psychosocial interventions (e.g., expressive writing, peer mentor support, storytelling interventions, HPV vaccination promotion). The postdoctoral fellow will actively participate in these funded studies, and contribute to scientific aspects (study design, data analysis, etc.) and implementation. The post-doctoral scholar will have opportunities to work on first authored manuscript writing, to develop new studies and to learn about grant writing including career development grants. The post-doctoral scholar will primarily work with Dr. Qian Lu, who has a track record of successfully obtaining extramural funding as a PI and mentoring career development grant awardees. The scholar will have opportunities to learn about multiple exciting research areas and methods. These research areas include psychosocial and behavioral interventions (social support, peer mentor, emotion regulation, expressive writing, health communication, vaccination uptake, cultural adaptation of interventions), well-being among cancer survivors and those with high risk (quality of life, adjustment, meaning, posttraumatic growth), understudied (young adult cancer survivors) and underserved populations (ethnic minorities, rural, low SES). The candidate will have opportunities to learn about randomized controlled trial, mixed quantitative and qualitative research methods, community based participatory research methods, and biopsychosocial framework (stress biomarkers). All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Planning, organizing, coordinating, and participating in scientific research projects. * Work closely with Research Manager to manage personnel tasks. * Work closely with Professor to determine specific goals or objectives to be obtained for each research project and evaluate research data, develop, and revise techniques or approaches to work problems. * Develop and/or recommend program intervention, prevention, and/or control strategies. * Provide expertise and services on behavioral research-related issues, data management, analysis, and interpretation. * Provide experience-based recommendations and research direction as requested on other studies conducted by, or on the behalf of the Professor and Research Manager. ELIGIBILITY REQUIREMENTS * Ph.D. in psychology, public health, or other related behavioral/social sciences discipline; or is currently enrolled in a doctoral degree program and will have fulfilled all degree requirements prior to beginning the postdoctoral fellowship * Knowledge and experience with cancer research * Be able to function in a separate and independent manner in the design and initiation of research experiments * Strong data analysis skills * Excellent oral presentation and writing skills * Advanced training in research methodology and strong publication record * Strong work ethic and commitment to becoming an independent scientist ADDITIONAL APPLICATION INFORMATION Applicants should send a cover letter stating research interests and experience, curriculum vitae, a list of two references, and up to two first-author reprint/writing sample(s) to Qian Lu, Ph.D., M.D. at (qlu at mdanderson.org) and Celia Wong-Meli, Ph.D. at (cwong5 at mdanderson.org) with the subject line "Postdoctoral Scholar Application". Initial appointment is one year, renewable upon mutual consent. The position opens immediately, and we accept and review applications - and make hiring decisions - on a rolling basis, so apply as soon as possible. Starting date is negotiable. Inquiries about the position should be addressed to Qian Lu at (qlu at mdanderson.org) and Celia Wong-Meli, Ph.D. at (cwong5 at mdanderson.org). POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

We are seeking a highly motivated and enthusiastic Postdoctoral Fellow to join Dr. Donna Hansel's research group in the Department of Pathology and Laboratory Medicine. Our lab studies the mechanisms of cancer invasion and metastasis in bladder cancer with a particular focus on understanding the cell signaling pathways to uncover novel therapeutic strategies. Our research employs a comprehensive array of models and methodologies, including cell lines, mouse xenograft models, human bladder cancer specimens, and multi-omics approaches to explore: 1) Mechanisms of cancer invasion and metastasis; 2) The impact of the tumor microenvironment on disease development and progression; 3 Identification of druggable targets to benefit patients. We offer a supportive, collaborative environment with ample resources for professional growth and career development. LEARNING OBJECTIVES * The candidate should be able to take initiative and be capable of working independently with appropriate supervision and guidance. * The candidate can critically evaluate relevant scientific advances and integrate this knowledge into research programs. * The candidate is expected to maintain a high level of productivity in the laboratory setting and can creatively overcome research hurdles through the resourceful use of information and technical expertise. * The candidate is expected to publish research results in peer-reviewed journals and present work at scientific conferences. * The candidate is also expected to seek the research grant opportunity to facilitate his/her career goal. Key Responsibilities * Research & Experiments: Design and execute cutting-edge experiments exploring tumor-immune interactions, leveraging advanced molecular, cellular, and in vivo methodologies. * Project Leadership: Lead collaborative projects, contributing to the design of protocols, experimental strategies, and data analyses. * Publication & Dissemination: Prepare and publish high-quality manuscripts and present findings at internal meetings and international conferences. * Mentorship: Provide guidance to graduate and undergraduate students, fostering a supportive and educational environment. * Lab Contributions: Contribute to a positive team culture by actively participating in lab meetings, brainstorming sessions, and shared responsibilities All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS * A recent Ph.D. or MD/Ph.D. in cancer biology, cellular and molecular biology, immunology, or a related field. * Proven track record of peer-reviewed publications or submitted manuscripts. * The applicant must have excellent writing and verbal communication skills. * Demonstrated technical expertise in cellular and molecular biology, immunohistology, imaging techniques, and animal experience. * Experience in immunology, genetic analysis, single cell as well as spatial-omics data analysis, and bioinformatic analysis (such as TCGA data analysis, large data analysis using R language, etc.) is highly desired. * Excellent communication skills, with the ability to work both independently and collaboratively. ADDITIONAL APPLICATION INFORMATION Interested candidates should submit the following documents 1. Cover Letter: A brief description of your background, research interests, and career goals. 2. Curriculum Vitae (CV): Include a list of publications, technical expertise, and contact information for three references. 3. Research Summary: A brief statement outlining past research experiences and future research aspirations (in 2 pages). Applications will be reviewed on a rolling basis until the position is filled. Only shortlisted candidates will be contacted for an interview. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral position is available in the Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Hussein A. Abbas, MD, PhD (primary mentor). We are seeking a Postdoctoral Fellow to join our leukemia research laboratory. The candidate must possess a robust background in acute myeloid leukemia, stem cell studies, preclinical studies, molecular biology, functional genomics, therapeutic targeting. The candidate will play a critical role in advancing our understanding of leukemia and/or the development of both in vitro and in vivo models to study these mechanisms. The scope of the position is highly translational research where targeted therapies, antibody, cellular therapies or other similar approaches will be employed. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Conducting experimental research on leukemia. * Immune and inflammation-based studies in leukemia * Developing and utilizing in vitro and in vivo models for leukemia research. * Performing molecular and cellular biology experiments. * Engaging in functional genomics studies. * Expertise in Incucyte or other cell killing assays * Expertise in flow cytometry analysis * Collaborating with both experimental and computational team members. Candidates will learn how to perform translational work. The work will be integrated with immunology, functional genomics and computational results that will allow multidisciplinary learning. Candidates will work in a team-based science allowing building collaborations. ELIGIBILITY REQUIREMENTS * Ph.D. in a relevant field (e.g., Molecular and Cellular biology, hematology etc). * Demonstrated experience with leukemias. * Proficient in cellular molecular biology techniques. * Ability to work independently as well as in a collaborative team environment. * Excellent communication skills, both written and verbal. * Independently able to read and interpret scientific literature, design experiments, troubleshoot experiments and present their work. ADDITIONAL APPLICATION INFORMATION ****************************************************************************************** Application Deadline: Consideration of applications will begin immediately and continue until the position is filled POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A postdoctoral position is available to study novel therapeutic targets and molecular mechanisms associated with therapeutic resistance in small cell lung cancer (SCLC) in the laboratory of Lauren Averett Byers, M.D. at the University of Texas MD Anderson Cancer Center in Houston, TX. The lab is largely interested using high-throughput screening to discover and validate potential drug targets and biomarkers of therapeutic resistance in SCLC. JOB KNOWLEDGE AND SKILLS: * Enthusiastic, highly self-motivated candidate, with the ability to function independently and as part of an interactive team * Experience in analysis of large "omic" datasets is required * A strong background in molecular biology, cellular therapy, and/or immunology/immunotherapy is preferred * Dedication to basic research, a true ¡§drive¡¨, is important * Excellent command of written and spoken English language * Prior publication record All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES The trainee will learn how to design and execute quantitative research in a safe, supportive, and inclusive environment, with the highest standard of ethical, responsible, and rigorous scientific research. The trainee will participate in professional development activities and in collaborative projects and present findings at a prestigious national/international conference, to prepare for the chosen career. ELIGIBILITY REQUIREMENTS Applications are invited from qualified individuals, interested in working in a translational research lab, with a Ph.D. and/or M.D. Preferred candidate should have less than 2 years of prior postdoctoral experience with background in cancer biology, biochemistry, cell biology, or molecular biology and be highly motivated to pursue a career in laboratory based biomedical research. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A postdoctoral fellow position is available in the Department of Epidemiology at The University of Texas MD Anderson Cancer Center. The role will focus on conducting computational research on clonal hematopoiesis of indeterminate potential (CHIP). Our group has recently completed a cohort of 25,000 cancer patients with targeted sequencing data, which we have used to identify CHIP. This dataset is linked to electronic health records and cancer registry data. We are interested in understanding how cancer therapy influences CHIP and how CHIP affects outcomes in cancer patients, including treatment response, treatment toxicity, and survival. Methodological projects are also available, such as optimizing the identification of CHIP in cancer patients. The ideal applicant will be prepared to lead one or more projects under the direct guidance of the principal investigator, with the goal of producing first-author publications and pursuing an academic career. Practical responsibilities include preparing analytic datasets, conducting statistical analyses, interpreting data, and developing presentations of results for conferences and publications. Experience with coding software such as Stata, R, SAS, or Python is required. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Planning, organizing, coordinating, and participating in scientific research projects. * Work closely with PI to determine specific goals or objectives to be obtained for each research project and evaluate research data, develop, and revise techniques or approaches to work problems. * Provide expertise on research-related issues, data management, analysis, and interpretation. * Conduct research activities (extensive literature reviews) and develop reports, presentations, and other documents. * Present findings of research projects to professional groups and prepare scientific documents for publication. * Advance skills in computational genetics and clinical informatics ELIGIBILITY REQUIREMENTS Highly motivated individuals who have obtained, or are about to obtain, a PhD in Biology, Bioinformatics, Computer Science, Epidemiology, Statistics, Genetics, or related fields are encouraged to apply. Relevant coursework in biostatistics is required. Physician-scientists with appropriate research experience are also eligible. A proven track record of publications, along with excellent written and oral communication skills, is required. ADDITIONAL APPLICATION INFORMATION Email the following to PI Kevin Nead (*********************) to apply: * Please include a statement with a description of background, interest in the position, relevant coursework or coding experience, prior experience with data analysis or research, and career/academic goals. * CV/resume * Names and email addresses of 3 references POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral position is available in the Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Kiochi Takahashi, MD (primary mentor). The candidate will engage in translational research related to hematologic malignancies. Specifically, the candidate will use various molecular biology and cellular biology techniques to study the specific function of genes relevant to hematologic malignancies. The candidate is expected to independently plan, design, and conduct research, analyze the data, and present the data in the meeting or in a published form. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Understand the functional genomics in leukemia. * Learn novel molecular biology and cellular biology techniques to investigate the function of specific genes of interest. * Learn the relationship between genetic abnormalities and disease phenotype. ELIGIBILITY REQUIREMENTS Successful candidates should have an MD, a PhD, or both credentials. Applicants must have a minimum of 3 years of experience in hematological research or cancer research. ADDITIONAL APPLICATION INFORMATION Work schedule of Monday - Friday, from 8:00 AM to 5:00 PM Applications will be accepted until the position is filled. Applicants must complete the application and upload all initial required documents within two weeks of applying. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A postdoctoral fellow position is available in the Section of Molecular Hematology & Therapy, Department of Leukemia at the University of Texas MD Anderson Cancer Center under the mentorship of Michael Andreeff, MD, Ph.D. We are seeking a highly motivated and innovative individual with advanced clinical experience in hematologic malignancies and technical expertise in cell, molecular, or cancer biology to lead a project focused on developing new analytical modalities for identifying novel vulnerabilities and creating hypothesis-driven, mechanism-based molecular targeting strategies for drug-resistant leukemias. The postdoctoral fellow will conduct research on cell death and cell survival pathways, as well as mechanisms of drug resistance in myeloid leukemia stem cells, through a combinatorial study using molecular biology methodologies. These include gene editing, mutation detection, gene and protein expression analysis, chromatin accessibility profiling, and evaluation of responses to drug treatments in both in vitro and in vivo leukemia cell systems. The goal is to broaden understanding of cell death regulators, signaling pathways, and leukemia microenvironmental factors, clarify their roles in drug resistance, and develop a mechanism-based approach to overcome therapeutic resistance. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES Learn how to collaborate with established and committed investigators in an interdisciplinary project involving cell culture, flow cytometry, mass cytometry, western blot analysis, immunohistochemistry, RT-PCR, DNA/RNA sequencing, and patient-derived xenograft leukemia and murine leukemia models using animals. Learn how to write report scientific results and will present findings in project meetings, national and international conferences, and high-impact scientific publications. ELIGIBILITY REQUIREMENTS The ideal candidate is a recently graduated physician-scientist with an M.D. and/or Ph.D. degree, possessing expertise in cell, molecular, and cancer biology, along with a strong practical background and comprehensive knowledge of cell death pathways and cell signaling. The candidate should also demonstrate proficiency in a series of laboratory techniques, including cell culture, drug treatment, and cell death assays, molecular cloning, flow cytometry, and/or experience with murine models of leukemia. Data analytic skills using innovative analytical approaches are highly desirable. The applicant enjoys providing both practical and theoretical training to students, fosters scientific collaboration within the research group, and exhibits excellent written and spoken English communication skills. Additionally, the candidate should have one or more first-author publications in high-impact, peer-reviewed journals in the field of hematology. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral Fellow position is available in the Department of Hematopoietic Biology & Malignancy at The University of Texas MD Anderson Cancer Center (MDACC) in Houston, TX. The fellow will work under the mentorship of Dr. Palaniraja Thandapani. The Thandapani Lab studies tRNA expression and epitranscriptomic regulation of gene expression in both normal and malignant hematopoiesis. We recently identified altered tRNA biogenesis as a marker of tumor-specific amino acid demand in T-cell acute lymphoblastic leukemia (T-ALL) (Nature, 2021). These findings highlight how tRNA deregulation can uncover novel, targetable metabolic and translational vulnerabilities in cancer. To advance this work, the lab leverages MDACC's extensive resources in primary human samples, patient-derived xenografts, and state-of-the-art genomic platforms. We apply next-generation and Nanopore sequencing to profile tRNA expression and epitranscriptomic changes across leukemia subtypes and normal hematopoietic compartments. These datasets are integrated with functional CRISPR screens, mechanistic approaches, and innovative therapeutic strategies (e.g., dietary modulation, RNA therapeutics, synthetic lethality) to define how tRNA dysregulation drives malignancy and to develop new therapeutic avenues for hematologic cancers. This position places strong emphasis on individualized mentoring, setting clear goals and timelines to support successful transition to academic or industry careers based on the fellow's interests. The lab offers direct, hands-on mentorship from a young PI while also providing access to guidance from senior faculty in the department and across the Division of Cancer Medicine. MD Anderson is part of the vibrant UT medical and scientific community located in the highly affordable and diverse Houston metropolis. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES The Postdoctoral Fellow will: * Design and conduct experiments, analyze data, and prepare manuscripts. * Participate in lab meetings, journal clubs, and research seminars. * Lead research focused on understanding how dysregulation of tRNA biogenesis contributes to hematologic malignancies. * Receive training in experimental design, data analysis, scientific writing, and oral presentation. * Build the skills necessary for independent career progression in academia or industry. ELIGIBILITY REQUIREMENTS Individuals with a PhD degree in RNA biology, Genetics, Hematology, Chemistry or related fields. Candidate should have strong background in molecular biology, RNA biology, genomics, genetics, or related fields. Preferred: prior experience studying hematopoiesis/ leukemia biology, mouse genetics and CRISPR screening. Proven track record of publications, excellent written and oral communication skills are required. ADDITIONAL APPLICATION INFORMATION For more information, visit the Thandapani lab webpage at *********************************************************************************************** POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

The University of Texas MD Anderson Cancer Center seeks an outstanding Postdoctoral Fellow to join the Department of Gastrointestinal Medical Oncology in advancing foundational artificial intelligence (AI) models for oncology. This position is embedded within MD Anderson's Moon Shots Program, an institutional initiative aimed at accelerating scientific discovery and translational impact to significantly reduce cancer mortality. The successful candidate will contribute to the development of next-generation multimodal AI systems that integrate diverse clinical and biological datasets to improve patient outcomes, enhance clinical operation, and advance precision oncology. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Develop, refine, and validate foundational AI models using large-scale multimodal oncology datasets. * Integrate heterogeneous data sources, including electronic health records, digital pathology images, radiology data, bulk and single-cell omics, and real-world clinical outcomes. * Design and implement novel computational frameworks for therapy response modeling, treatment optimization, clinical trial matching, and patient care enhancement. * Collaborate closely with clinicians, computational scientists, biologists, and disease groups across MD Anderson. * Disseminate research findings through peer-reviewed publications and presentations at national and international scientific meetings. * Assist in grant development and project coordination as needed. ELIGIBILITY REQUIREMENTS * PhD in Computer Science, Computational Biology, Bioinformatics, Electrical Engineering, Biomedical Engineering, or a related quantitative discipline. * Demonstrated expertise in machine learning or deep learning, including familiarity with large language models, multimodal architectures, or generative AI. * Proficiency in Python and modern machine learning frameworks (e.g., PyTorch, TensorFlow, JAX). * Experience working with biological, clinical, or other high-dimensional datasets. Preferred: * Background in oncology, cancer biology, immunology, or translational research. * Experience with foundational model development, self-supervised learning approaches, or large-scale distributed training. * Familiarity with EHR data structures, digital pathology workflows, or multi-omics integration. * Strong publication record demonstrating rigor, innovation, and independence. ADDITIONAL APPLICATION INFORMATION Access to one of the richest and most comprehensive cancer datasets worldwide, enabled by MD Anderson's status as the top-ranked cancer center with the nation's largest oncology patient volume. * Integration into the Moon Shots Program, providing unique opportunities for high-impact translational research, cross-disciplinary collaboration, and accelerated clinical application. * A highly collaborative and well-resourced environment with strong institutional support for AI, data science, and precision oncology initiatives. * Competitive compensation and benefits in accordance with NIH and MD Anderson guidelines POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

The Cascone Lab at the world-renowned University of Texas MD Anderson Cancer Center is seeking one or more highly motivated and ambitious postdoctoral fellows to join a well-funded, dynamic, and question-driven research program focused on advancing the science of lung cancer immunology and immunotherapy. Under the mentorship of Tina Cascone, M.D., Ph.D., a physician-scientist and Associate Professor with tenure, and Director of Translational Research in the Department of Thoracic/Head and Neck Medical Oncology, successful candidates will engage in innovative translational research aimed at unraveling the immune-mediated mechanisms of tumor response and resistance to therapy in non-small cell lung cancer. This fellowship offers a unique and exciting opportunity to contribute to cutting-edge, high-impact projects at the intersection of preclinical discovery and clinical application. Research will involve both state-of-the-art murine models and biospecimens from pioneering clinical trials testing immune checkpoint inhibitors as well as standard-of-care chemoimmunotherapy regimens in patients with surgically resected non-small cell lung cancer. If you are passionate about translating scientific discovery into therapeutic innovation and thrive in a collaborative, mission-driven research environment, we encourage you to apply. LEARNING OBJECTIVES Key Research Focus * Mechanistic studies of immune checkpoint blockade in lung cancer * Analysis of tumor-immune interactions in response and resistance to therapy * Regulation of systemic and local anti-tumor immunity under therapeutic pressure * Utilization of syngeneic and genetically engineered mouse models * Integration of human clinical data with experimental immunology * Contribution to the development of novel combination strategies and biomarkers What We Offer * A collaborative, high-energy environment at a top-ranked cancer center * Close mentorship from a physician-scientist involved in leading clinical trials * Access to cutting-edge technologies, including immunogenomics, single-cell and spatial transcriptomics, flow cytometry, and immune profiling * Opportunities for first-author publications, grant development, and career advancement * Competitive salary and comprehensive benefits All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS Required: * Ph.D., M.D./Ph.D., or equivalent in tumor immunology, molecular biology, cancer biology, or related fields * Demonstrated experience with immune checkpoint inhibitors, T cell-based therapies, or tumor immunology * Proficiency in handling and analyzing murine cancer models, particularly syngeneic systems * Strong experimental, analytical, and communication skills * Self-motivated, collaborative, and driven to make a scientific impact Preferred (but not required): * Familiarity with oncogenic signaling, biomarkers of response/resistance, or cancer metabolism * Experience with multi-omics approaches, such as immunogenomics or transcriptomics * Background in evaluating human tumor samples and integrating clinical data ADDITIONAL APPLICATION INFORMATION ******************************************************************************************** POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral position is available in the Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Pavan Bachireddy in the Department of Hematopoietic Biology & Malignancy. We are seeking a talented and highly motivated Postdoctoral Fellow interested in understanding the evolutionary dynamics of measurable residual disease (MRD) progression within the bone marrow microenvironment. Our lab uses unbiased, high-throughput technologies to decode the rules of interaction among diverse cell types in the tumor milieu that determine patient outcomes to cancer immunotherapy, primarily in hematologic malignancies (NEJM 2016; Cell 2018; Sci Transl Med 2020; Blood 2021; Cell Reports 2021; Cancer Cell 2023). We are especially interested in Fellows with molecular biology expertise to interrogate subclonal evolution, using integrative analyses of jointly measured transcriptomic, proteomic and epigenomic measurements at single cell resolution. Furthermore, in vitro genome-editing and in vivo experiments will be critical approaches to validate and extend our findings. The Postdoctoral Fellow will have access to the extensive research platforms at MD Anderson and the broader Texas Medical Center, including computation clusters, single-cell core facilities, epigenetics core facilities, flow cytometry facilities, drug screening cores, and animal colonies, among many others. Dr. Bachireddy is also deeply committed to the career growth and success for each member of the laboratory. Such mentorship should be intentional, planned and tailored to each member of the group - thus the laboratory operates with a primary goal of fostering career goals and development for each individual. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES The Postdoctoral Fellow will conduct experiments, perform data analysis and prepare manuscripts in addition to attending lab meetings, journal clubs, and research seminars. The Postdoctoral Fellow's primary research focus is on hematologic malignancies that determine patient outcomes to cancer immunotherapy. The Postdoctoral Fellow will train, learn and study design, data analysis and manuscript writing as well as learn to give articulate oral presentations in preparation for career progression. The fellow will lead work focused on 1) interrogation of factors defining MRD; 2) evolutionary modeling of cancer-immune interactions over time and 3) identification of programs driving MRD progression across myeloid malignancies, using multiple cutting-edge technologies as well as standard cell culture and immunologic approaches. Because Dr. Bachireddy is also the Scientific Director of the ECLIPSE (Evolution of Cancer, Leukemia and Immunity Post Stem Cell transplant) platform, the fellow will have significant interaction and access to the vast immunogenomic and computational resources of the physically adjacent ECLIPSE platform. We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must. ELIGIBILITY REQUIREMENTS Individuals with a PhD degree in immunology, molecular biology, genomics, genetics, or related fields. Experiences that are desirable (but not required) include: immunology (e.g. T cell assays), CRISPR, and/or next-gen sequencing (bulk or single cell genomics) within myeloid malignancies. Candidate should have the ability to prioritize and manage multiple projects. Proven track record of publications, excellent written and oral communication skills are required. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral Fellow position is available in the department of Neurosurgery under the mentorship of Joseph McCarty, PhD. The postdoctoral fellow position will involve basic and translational research in the area of brain tumor cell biology and mouse models of primary and metastatic brain cancer. There will be a particular emphasis on the brain microenvironment, including studies of how primary and metastic tumor cells co-opt the neurovascular unit/blood-brain barrier for selective growth and survival. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES The post-doc will receive training and mentoring in the use of mouse models and in vitro culture systems to study cell adhesion and signaling pathways involved in tumor cell-stromal cell interactions. Biochemical, molecular genetical and cell biological techniques will also be emphasized. ELIGIBILITY REQUIREMENTS The applicant should have a PhD and/or MD as well as peer-reviewed publications or manuscripts under review in internationally recognized journals. A strong background in biochemistry, molecular biology, and cell biology is also required. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

We are seeking highly motivated postdoctoral fellows to join a multidisciplinary research program in the molecular epidemiology of lymphoid malignancies. Based in the Departments of Epidemiology and Lymphoma & Myeloma at The University of Texas MD Anderson Cancer Center, our work bridges molecular, population, and clinical research. We investigate how inherited genetic variation, clonal hematopoiesis, and precancerous conditions influence the risk, progression, and outcomes of blood cancers, including chronic lymphocytic leukemia, multiple myeloma, and diffuse large B-cell lymphoma. By integrating germline and somatic genomic data with large-scale cohort, biobank, and clinical datasets, we identify risk factors, model disease trajectories, and develop precision tools for cancer risk prediction. Supported by funding from the Cancer Prevention and Research Institute of Texas (CPRIT) and the National Cancer Institute, the program provides access to exceptional resources, including high-performance computing, large and diverse population datasets, and a collaborative, data-rich environment. LEARNING OBJECTIVES Postdoctoral fellows will work at the interface of population science, computational biology, and clinical oncology. Potential projects include: Developing computational phenotyping methods to identify precursor conditions in large cohorts. Characterizing clonal growth trajectories in B-cell precursors and their somatic drivers. Investigating the combined effects of inherited and acquired genomic alterations on cancer risk and prognosis. Fellows will be supported in developing independent research directions, publishing in high-impact journals, and presenting at national and international meetings. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations ELIGIBILITY REQUIREMENTS Ph.D., M.D./Ph.D., or equivalent degree in epidemiology, genetic epidemiology, bioinformatics, computational biology, or a related field. Demonstrated experience in genomic data analysis and statistical programming (R, Python). Interest in cancer epidemiology and early detection of lymphoid malignancies. Strong written and oral communication skills, with a publication record. POSITION INFORMATION MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

The Shengqing (Stan) Gu lab at MD Anderson Cancer Center seeks a highly motivated Postdoctoral Fellow with a strong biomedical research background to join our team. Our laboratory focuses on understanding how dysregulation of cell-cell interactions shape tumor development and drive immune evasion - a key process underlying cancer progression and therapy resistance. Ongoing projects include: (1) Modulating cancer antigen presentation to potentiate immunotherapy; (2) Mapping the evolutionary trajectories of immune evasion in cancer development. To address these questions, we integrate various cutting-edge experimental and computational approaches in the areas of functional genomics, single cell/spatial multi-omics, cell biology, biochemistry, data mining, machine learning, and mathematical modeling, among others. This position offers an exceptional opportunity to conduct interdisciplinary research at the intersection of cancer biology, immunology, and computational biology within a highly collaborative environment. More research details can be found at: *************************************************************************************** All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES The incoming fellow will receive training and conduct research at the broad intersection of cancer immunology and computational biology, which will help build a strong portfolio for their future career development. The fellow will work closely with local experimental and/or computational collaborators in seeking to enhance the efficacy of cancer immunotherapy, such as by modulating cancer antigen presentation. The fellow will also benefit from collaborations with former colleagues of Dr. Gu at many institutes. ELIGIBILITY REQUIREMENTS Highly motivated individuals who have obtained or are about to obtain a PhD in Biology, Bioinformatics, Computer Science, or related areas are encouraged to apply. Proven track record of publications, excellent written and oral communication skills are required. ADDITIONAL APPLICATION INFORMATION Dr. Gu is strongly committed to the professional fulfillment and career advancement of all trainees. He will work on creating a successful transition plan to academia or industry for the fellow in accordance with their evolving preferences. The fellow will have access to the rich research platforms at MD Anderson and more broadly the Texas Medical Center, including computation cluster, single-cell core facility, epigenetics core facility, flow cytometry facilities, drug screening core, animal colony, among many others. The stipend will follow the NIH guideline: ******************************************************************* Dr. Gu graduated from University of Toronto with a PhD in Medical Biophysics, did postdoctoral training at Harvard Medical School and Dana-Farber Cancer Institute, and joined MD Anderson Cancer Center as Assistant Professor in November 2022. He has excellent track record in highly collaborative and interdisciplinary research in cancer biology, immunology, and computational biology, as demonstrated by recent (co)first and corresponding author papers/preprints: Cancer immunology: (Jiang, Gu, Pan et al., Nature Medicine, 2018; Gu, Wang, Hu et al., Genome Biology, 2020; Shi, Gu et al., Clinical Cancer Research, 2020; Gu, Zhang, Wang, Jiang et al., Cancer Discovery, 2021; Wang, Tokheim, Gu, Wang et al., Cell, 2021; Zeng, Gu et al., Cancer Immunology Research, 2022) Computational biology: (Gu et al., PNAS, 2021; Zeng, Gu et al., Science Advances, 2022; Chen et al., biorxiv, 2025) Leukemia biology: (Gu, Chan, Mohi et al., Blood, 2016; Gu et al., Leukemia, 2018) POSITION INFORMATION Postdoc Fellow MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA. This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience. MD Anderson offers compensated trainees: * Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week * Group Dental, Vision, Life, AD&D and Disability coverage * Paid Education Vacation and Sick Leave * Paid institutional holidays, wellness leave, childcare leave and other paid leave programs * Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans * Employer paid life, AD&D and an illness-related reduced salary pay program * Health Savings Account and Dependent Care Reimbursement flexible spending accounts * Fertility benefits * State of Texas longevity pay * Extensive wellness, fitness, employee health programs and employee resource groups Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A Postdoctoral position is available in the Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Hussein A. Abbas, MD, PhD (primary mentor). We are seeking a Postdoctoral Fellow to join our leukemia research laboratory. The candidate must possess a deep and robust background in molecular and cellular biology, with a primary focus on immunology of T and NK cells, with extensive experience in co-culture assays, flow cytometry, immune assays and in vivo murine studies. The candidate will play a critical role in advancing our understanding of immune biology of leukemias such as AML, mastocytosis and immune cell interactions and/or the development of both in vitro and in vivo models to study these mechanisms. The scope of the position is highly translational research. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. LEARNING OBJECTIVES * Conducting experimental research on leukemia. * Immune and inflammation-based studies in leukemia * Developing and utilizing in vitro and in vivo models for immune biology and leukemia research. * Performing molecular and cellular biology experiments. * Engaging in functional genomics studies. * Expertise in cell killing and co-culture assays * Expertise in flow cytometry analysis * Collaborating with both experimental and computational team members. Learning Objectives: Candidates will learn how to perform translational work. The work will be integrated with immunology, functional genomics and computational results that will allow multidisciplinary learning. Candidates will work in a team-based science allowing building collaborations. ELIGIBILITY REQUIREMENTS * Ph.D. in a relevant field (e.g., Immunology, Molecular Biology or Cellular Biology) with a focus on immunology * Demonstrated experience with immunology and mouse models. * Proficient in cellular molecular biology techniques. * Familiarity with flow cytometry. * Ability to work independently as well as in a collaborative team environment. * Excellent communication skills, both written and verbal. * Independently able to read and interpret scientific literature, design experiments, troubleshoot experiments and present their work. * Up to 1 year from time of PhD graduation. ADDITIONAL APPLICATION INFORMATION ****************************************************************************************** POSITION INFORMATION Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

The Wang Laboratory at MD Anderson Cancer Center is a computational biology research lab. We apply innovative bioinformatics approaches to dissect the tumor 'ecosystem', deeply profile tumor cells and cells of the tumor microenvironment as well as tumor-immune-stroma crosstalk at single-cell resolution and in the spatial context. The lab's key focus areas include: 1) Transition from premalignant lesions to invasive cancer; 2) Evolution of metastasis from a localized tumor; 3) Dynamic response to anti-cancer therapies and the development of therapeutic resistance. Leveraging cutting-edge single-cell and spatial multi-omics technologies, cellular imaging, and innovative bioinformatics tools and computational frameworks, we aim to harness the potential of big data to fight cancer. Our overarching goal is to advance our understanding of the cellular & molecular cues underlying early tumorigenesis, disease progression, and the development of therapy resistance and translate our novel discoveries into improved patient care. We are seeking multiple talented and highly motivated Postdoctoral Fellows with a strong background in bioinformatics and a passion for exploring the heterogeneity and evolution of tumor cells and tumor microenvironment using the state-of-the-art single cell and spatial multi-omics approaches. LEARNING OBJECTIVES Gain skills in single cell, spatial omics, and imaging data analysis, immunogenomics, immune-informatics, and cancer-specific bioinformatics. Develop expertise in study design, data analysis, data interpretation, presentation, manuscript and grant writing All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS Individuals with a PhD degree in computational biology, bioinformatics, data science or a related field are encouraged to apply. A strong computational background, proficiency in R and at least one additional scripting language (e.g., Python) and knowledge in biostatistics are required. Experience working with single cell and spatial omics data analysis and high-performance computing environment (Unix/Linux) is highly preferred. A good understanding of cancer biology, immunology, cell biology, and molecular biology is also preferred. Proven track record of publications, excellent spoken and written communication skills are required ADDITIONAL APPLICATION INFORMATION Interested applicants should send a Cover Letter specifying past research experience/skills/accomplishments, a Curriculum Vitae and the contact information of three (3) Referees to Dr. Linghua Wang at ********************** with the subject line entitled "Postdoctoral Fellow - Application - Applicant's Name". POSITION INFORMATION Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************ FACULTY MENTOR Dr. Linghua Wang

A postdoctoral fellow position is available in the Department of Genomic Medicine. We seek a driven and technically adept Postdoctoral Fellow to develop and deploy Artificial Intelligence models to advance cancer drug discovery by solving key challenges, from target identification to drug design and development. LEARNING OBJECTIVES Gain an understanding of key components and bottlenecks in cancer drug discovery. Develop an understanding of a hands-on experience in data science analytics and model development to address these bottlenecks. This includes learning to train, benchmark, and deploy deep neural networks and foundation models. Learn to apply iterative, human-in-the-loop AI models in the context of cancer drug discovery and validate these models in collaboration with experimental researchers. Develop hands-on expertise in AI applications within one or more key areas: patient profiling and imaging data science; structural biology and protein structure prediction; drug design; and forecasting models for drug resistance. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS Individuals with a PhD in computer science and a strong desire to apply and advance their skill set with chemical and biological structural data are encouraged to apply. A strong computational background is required. Expertise with PyTorch and torch-geometric, or equivalent technologies, is essential. Experience with other deep learning and generative methods is preferred. Experience working in a high-performance computing environment (Unix/Linux) using state-of-the-art GPU computing is required. Alternatively, candidates with a PhD in computational biology and demonstrable experience in Python, Jupyter Notebook, or equivalent technologies, applying bioinformatics or computational techniques to biomedical data, are encouraged to apply. Some understanding of databases related to several of the following-cancer genomes, structural biology, and chemistry is highly desired. Importantly, candidates' eagerness to grow in these related fields is crucial. This position will involve collaboration with multidisciplinary partners, requiring excellent written and verbal communication skills. The role will also include reporting and sharing findings with the broader cancer and drug discovery research community through published articles and presentations. ADDITIONAL APPLICATION INFORMATION The appointment is immediately available. The appointee is expected to work forty hours per week, including instruction and literature studies in the computational life sciences to deepen the successful candidate's knowledge beyond data science alone. This position reports to Dr. Bissan Al-Lazikani in the Genomic Medicine Department. Consideration of applications will begin immediately and continue until the position is filled. POSITION INFORMATION Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************

A postdoctoral fellowship position is available in the Department of Imaging Physics in the laboratory of Kristy Brock, Ph.D. The Morfeus Lab at MD Anderson ( ********************************************************************************************* is led by Dr. Kristy Brock. Our research is focused on the development and application of deformable image registration algorithms, artificial intelligence (AI) algorithms, biomechanical modeling, and image guided cancer therapy technologies for strategic research collaborations and clinical translation. Our lab is a highly collaborative research training environment in a state-of-the-art imaging facility and world class resources. Ongoing projects seeking postdocs include: 1) Image-guided liver surgery 2) Image-guided head and neck surgery 3) Cancer risk assessment and outcomes prediction using artificial intelligence 4) Validating in vivo imaging signals using correlative pathology 5) Image-guided focal liver ablation 6) Dose accumulation for personalized adaptive radiation therapy LEARNING OBJECTIVES This postdoctoral fellow will engage in computational research projects in image guided cancer therapy, including research, design, and implementation of deformable image registration, biomechanical modeling, and artificial intelligence technologies. The fellow will expand their knowledge and skills in imaging physics, data mining, predictive modeling, clustering, and classification and will develop, train, and apply deep learning in large data environments. The fellow will help to guide research and clinical collaborations and work with collaborators to integrate image guided cancer therapy models and technologies into the clinical workflow. They will collaborate and coordinate with research and clinical stakeholders and communicate findings via abstracts, poster and podium presentations, and publications. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. ELIGIBILITY REQUIREMENTS Applicants should have earned a PhD in one of the natural sciences, computer sciences, engineering, or related fields or a medical degree. Experience with machine learning and deep learning techniques, statistical modeling, biomechanical modeling, or image registration and analysis is preferred. POSITION INFORMATION Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. ************************************************************************************************ FACULTY MENTOR Dr. Kristy Brock