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Principal research scientist jobs in Lower Merion, PA

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  • Research Scientist IV

    Source One Technical Solutions 4.3company rating

    Principal research scientist job in Spring House, PA

    Source One is a consulting services company and we're currently looking for the following individual to work as a consultant with our direct client, a global Pharmaceutical Manufacturing client in Spring House, PA. No Third-Party, No Corp to Corp, No Sponsorship. Must be able to work in the US and must not require sponsorship for employment visa status now or in the future (e.g., FI, H1-B status) Title: Research Scientist IV Location: Spring House, PA Onsite (Mon-Fri, 40 hours) Contract Duration: 12 months, with likely extension Pay Rate: $67.88 per hour (w2) Key Responsibilities: • Support membrane protein expression and purification. • Conduct protein production, purification and characterization. • Characterization and quality check of membrane proteins to support biotherapeutics development. • Collaborate effectively in a multi-team environment. • Contribute to both internal and external efforts in membrane protein production. Education: • Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required. Required Skills: • Experience with membrane protein expression and optimization, purification, and characterization of proteins • Well-versed with analytical characterization to determine quality, conformation, purity and stability • Knowledge of protein expression construct design and optimization, and expression platforms • Excellent communication skills to collaborate with internal and external partners Preferred: • Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs • Experience in independently operating AKTA FPLC and analytical HPLC instruments • Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery • Knowledge and experience with CROs for protein production
    $67.9 hourly 2d ago
  • Principal Protein scientist

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Spring House, PA

    Duration: 12Months Required Skills Role is 100% onsite in Spring House, PA Bachelor's degree is required #1 Required skill: Must have processing protein production, purification experience #2 Required skill: Must have analytical characterization experience Membrane protein experience, a huge plus Must have 2-4 years of experience Will attend group meetings 60%-70% of the role will be lab based work Will do data capturing Description: Key Responsibilities: Support membrane protein expression and purification. Conduct protein production, purification and characterization. Characterization and quality check of membrane proteins to support biotherapeutics development. Collaborate effectively in a multi-team environment. Contribute to both internal and external efforts in membrane protein production. Qualifications Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required. Experience and Skills: Experience with membrane protein expression and optimization, purification, and characterization of proteins Well-versed with analytical characterization to determine quality, conformation, purity and stability Knowledge of protein expression construct design and optimization, and expression platforms Excellent communication skills to collaborate with internal and external partners Preferred: Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs Experience in independently operating AKTA FPLC and analytical HPLC instruments Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery Knowledge and experience with CROs for protein production About US Tech Solutions: US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit ************************ US Tech Solutions is an Equal Opportunity Employer.All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Recruiter Details: Name: I.Prudvi kumar Email: ******************************* Internal Id: 25- 54564
    $95k-143k yearly est. 2d ago
  • Scientist 4 - Research and Development

    Pyramid Consulting, Inc. 4.1company rating

    Principal research scientist job in Spring House, PA

    Immediate need for a talented Scientist 4 - Research and Development. This is a 12+ Months Contract opportunity with long-term potential and is located in Spring House, PA (Onsite). Please review the job description below and contact me ASAP if you are interested. Job ID:25-94738 Pay Range: $57 - $67/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location). Key Responsibilities: Support membrane protein expression and purification. Conduct protein production, purification and characterization. Characterization and quality check of membrane proteins to support biotherapeutics development. Collaborate effectively in a multi-team environment. Contribute to both internal and external efforts in membrane protein production. Key Requirements and Technology Experience: Skills-Experience in independently operating AKTA FPLC and analytical HPLC instruments. Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs. Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required. Experience with membrane protein expression and optimization, purification, and characterization of proteins Well-versed with analytical characterization to determine quality, conformation, purity and stability Knowledge of protein expression construct design and optimization, and expression platforms Excellent communication skills to collaborate with internal and external partners Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs Experience in independently operating AKTA FPLC and analytical HPLC instruments Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery Knowledge and experience with CROs for protein production Our client is a leading Pharmaceutical Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration. Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.
    $57-67 hourly 2d ago
  • Associate Scientist

    Pacer Group 4.5company rating

    Principal research scientist job in Lansdale, PA

    Job Title: Scientist Duration: 12 Months Pay Rate: $32/hr on W2 Education: • B.S. in Biology, Bio/chemistry, Bio/chemical Engineering, or related science or engineering field. • At least 1yr of laboratory experience in Molecular Biology, Protein Biochemistry, and/or upstream process development. The ideal candidate would possess: • General laboratory skills, experience with aseptic manipulations, pipettes • Experience in culturing microbial cells at different scales • Experience in protein biochemistry and analytical methods (e.g. SDS-PAGE, Western Blot, ELISA) • Basic knowledge of fermentation • Experience using formulas and linking spreadsheets in Excel • Highly computer literate. Capable of quickly learning and adapting to new computer programs. Strong computer, scientific, and organizational skills • Excellent communication (oral and written) and attention to detail • Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude • Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies. Additional Requirements: • This position will require occasional off-hour and/or weekend work (10-20% of hours may be “off-shift”) • This position will require work with Biosafety Level-1 organisms Responsibilities: Scientist responsibilities include, but are not limited to, the following: • Prepare laboratory reagents, solutions, and culture media • Perform lab-scale fermentation runs to meet different needs • Set up process equipment for lab-scale experiments • Perform analytical assays • Analyze, collate, track, and report data back to client staff members • Maintain records and test results following good laboratory practices (GLP) guidance • Work independently and efficiently • Document work clearly and perform tests accurately • Communicate effectively with client staff members
    $32 hourly 2d ago
  • Cell Therapy Process Development Scientist (Autologous)

    Insight Global

    Principal research scientist job in Spring House, PA

    Our large pharmaceutical clients is seeking a Scientist to join their growing Process Development team within the Cell Therapy Development organization in Spring House, PA. This person will be focused on CAR-T cell manufacturing and will spend about 80% of their time in the lab setting up and running automation instruments for T cell manufacturing (primarily Prodigy), doing manipulation with cells, sampling, and making sure equipment is running properly. They will primarily be focused on process development in CAR-T and its transition to manufacturing. In this role, the successful candidate will be involved in process design, unit operation development, and parameter optimization studies resulting in the development of new production processes. Other responsibilities include: Design and execute process development studies using sound scientific and engineering principles to develop and improve unit operations used for production of autologous T-cell therapies, Identify, critically assess and evaluate opportunities to improve manufacturing outcomes such as improving success rate, throughput, reducing cost, process time and product quality of the final drug product. Lead/contribute to the design and execution of phase-appropriate process development study plans, identifying process parameters and appropriate ranges to be assessed for optimal experimental design of the study. Investigate improvements to current processes used for T-cell selection, activation, transduction and expansion together with their impact on critical quality attributes. Author reports detailing experimental work and summarizing results, protocols, technical reports and SOPs. Support technology transfer activities, writing protocols, reports, and performing and coordinating activities to support successful manufacturing Qualifications: Minimum of a Bachelor's Degree in a related field of study Minimum of 2 years of process development for autologous cell therapy or CAR-T manufacturing Prior experience working with bioreactors (preferably Xuri) Salary: $80,000-$100,000 (flexible based on experience) Hours: Monday-Friday, 8:00am-5:00pm Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year PTO: 10 PTO days, 6 paid sick days annually & paid Holidays Benefits: Medical, Dental, Vision and 401K plans available Exact compensation may vary based on several factors, including skills, experience, and education. Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.
    $80k-100k yearly 2d ago
  • Research Scientist

    Lesaffre Group 4.4company rating

    Principal research scientist job in West Chester, PA

    Who we are Envera LIC, LLC is part of the Lesaffre family who is a key global player in the fermentation of microorganisms (yeasts and bacteria) for baking, taste, healthcare, and industrial biotechnology. This story began more than 170 years ago in northern France, and, thanks to our entrepreneur spirit and our innovative approach, we are constantly developing. Lesaffre's global presence includes 11,000 employees from 96 nationalities and a 3-billion-euro turnover. We work with customers, partners, and researchers to develop essential nutrients and bio actives that strengthen human health, optimize animal well-being, and improve plant nutrition. We believe in the incredible potential of microorganisms as the greatest means to better nourish and protect the planet. Fermentation is one of the most promising answers to the challenge of nourishing 9 billion people in a healthy way by 2050. Envera is a legal entity of Lesaffre located in West Chester, Pennsylvania. Envera manufactures bacteria solutions for Lesaffre BUs and different market segments such as wastewater treatment, bioremediation, cleaning solutions, and many other areas where bacteria can play a key role. What we offer * The opportunity to represent a passionate organization focused on innovation and sustainability * A great 401K plan, affordable benefits, and 10 paid holidays * The ability to utilize your experience and knowledge to make a real impact What you bring to the table The aptitude to work within our research laboratory, overseeing the design, execution, and reporting of experiments that support customer applications, product development, and production. Having the skillset to primarily focus completing projects through effective coordination and direct involvement in lab work. A few responsibilities you will have as Research Associate * Manage multiple concurrent research programs. * Employ impeccable aseptic technique. * Routinely perform various techniques such as: * Flow Cytometry, Standard Microbiology, Enzyme Assays, and Automation * Develop, optimize, and implement enzyme and microbiology assays. * Collaborate with team members on large-scale projects or work independently on smaller projects. * Document research procedures and SOP's. * Independently review literature to aid project development. * Directly supervise projects and equipment in R&D Department. * Set up studies, projects, new methods, completing required analysis, and organizing data * Prepare summary reports and train technicians on new or revised methods * Setting up new equipment, validating prior to use, and reviewing controls * Complete and organize equipment maintenance, troubleshooting issues, and supervising calibrations To succeed you must have * Accomplished in all general lab tasks which include standard laboratory methods and procedures. * Bachelor's Degree in Microbiology or Biology with 10 plus years' experience in a similar position, Master's with 8 plus years' experience, or PhD with 3 plus year's experience * Flow Cytometry experience preferred * Experience in soil bioremediation and wastewater treatment a plus * Strong working comprehension of Microsoft office tools such as Excel, Word, PowerPoint, and Outlook, as well as electronic lab notebooks * Working knowledge of Gantt charts and other tools for project management. * Ability to independently author reports and procedure manuals Our Core Values: Passion, respect, trust, entrepreneurship, and humility Envera provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
    $68k-101k yearly est. 49d ago
  • Senior Scientist, Analytical Research & Development

    Veranova L P

    Principal research scientist job in West Deptford, NJ

    Who We Are: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Sr. Scientist is responsible for the implementation, development, and validation of analytical test methods in support of process research, and cGMP production with emphasis on development of LC, GC, GC-MS and LC/MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc) methods for small molecules, ADCs, Oligonucleotides and Peptides Major support functions include sample analysis by various analytical techniques including HPLC, GC, LC-MS/MS, GC-MS, ICP-MS, CE, SEC-MALS, CE-SDS, cIEF, NMR, KF, titrations, and instrumental and wet chemical techniques. Other duties may involve analytical method modification, development, and validation. The incumbent may function as the primary contact on one or more development projects. In- depth involvement with the project team concerning the chemistry of the project and analytical chemistry needs is expected Core Responsibilities: Develop and validate new analytical procedures. Independently, detects and solves complex problems of high technical difficulty. Perform sample analysis using various analytical techniques (e.g., LC, GC, LC-MS, GC-MS, ICP-MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc.), interpret results, and prepare high-quality documentation such as protocols, analytical reports, and summary reports. Document all analyses per SOPs. Prepare SOPs, test methods, and other GMP documentation. Independently, detect and solve complex problems of high technical difficulty. Apply knowledge and expertise from multiple disciplines (including QA, QC, Analytical and production) to achieve project goals. Conduct investigations independently. Troubleshoot analyses and instruments. Support qualification of reference materials. Develop new analytical procedures. Validate analytical methods. Prepare and review scientific reports. Interface with internal and external clients. Qualifications: PhD in Analytical Chemistry or equivalent Minimum of 8 years' experience in a GMP environment. Minimum of 5 years' experience in method development and validation for small molecules Active Pharmaceutical Ingredients (APIs). Experience with Process Development of APIs. Experience with LC, GC, GC-MS, LC-MS, IC, spectroscopy, and wet chemistry. Experience mentoring staff members in an analytical department. Formal project management training. Experience with writing method validation protocols and reports desirable. Experience with Microsoft Office and other complex computer software (UPLC, Empower 3) desirable. Our Commitment: Health & Wellness: Comprehensive health & Wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Comprehensive total compensation package that includes competitive base salary, Defined Contribution Pension program, eligibility for performance-based bonuses, and attractive 401(k) Plan with company match. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova an inclusive culture is integral to our values. We are committed to ensuring that everyone can bring their full self to work and thrive in their career. How to Apply: At Veranova, we are on a misson to meet people that believe in our values and can contribute to the team in a variety of ways. Please visit **************** to view all open roles and join our Talent Community to stay connected and learn about opportunities as they arise. We value a range of experiences and perspectives. If you want to be part of improving and saving the lives of patients, we encourage you to apply regardless of whether you meet every qualification listed. If you are a veteran, first responder, or in the process of transitioning from service member to civilian life, we encourage you to apply. Your experience brings invaluable skills and insights that can contribute to our team. For applicants who may require a reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email to ****************************** in order to confirm your request for an accommodation. Please include the job number, title, and location of role. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Veranova employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. Important Notice Regarding Recruitment Scams: Veranova is committed to providing a professional and secure recruitment experience for all applicants. Unfortunately, fraudulent job postings and recruitment scams are becoming more prevalent. We want to ensure that all candidates are aware of potential scams. Please see our notice here. Legitimate communications from Veranova will only come from official email addresses using our domain: @veranova.com. Legitimate LinkedIn communications will only come from active Veranova employees. Veranova will never ask candidates for sensitive personal information during the application process (e.g., bank account details or social security number). Veranova will never ask candidates for payment (e.g., for equipment, training, or background checks). If you have any doubts or concerns about the authenticity of a job posting, please reach out to our HR department: ********************* (US) or ***************** (UK). All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice.
    $88k-125k yearly est. Auto-Apply 60d+ ago
  • Senior Scientist - Ink Formulation

    Penn Color 4.5company rating

    Principal research scientist job in Hatfield, PA

    Who We Need We are seeking a Senior Scientist to join our R&D Inks & Coatings group. You will work alongside an outstanding team in designing and formulating both water and solvent based inks ad coatings for printing applications (primarily for rotogravure and flexography). Responsibilities: Design and formulate water & solvent based inks and coatings. Modify existing inks and coatings to meet customer requirements. Lead and support projects from lab formulation to commercialization. Work closely with raw material suppliers and internal procurement department for bringing alternate raw materials or for qualifying new raw materials. Generate and analyze data after conducting standard tests on inks and coatings. Occasional domestic travel to customers for attending technical meetings or print trials. Interact with customers to understand and define the scope of project. Regularly interact with sales, procurement and production during various stages of new product development. Other duties as assigned. Knowledge/Skills/Experience: 5-8 years minimum experience in formulating inks for printing applications. Prefer experience in ink formulation for rotogravure printing process. Experience or familiarity with printing processes such as rotogravure, flexography, screen printing and industrial digital printing. Knowledge on working with film/substrates like PVC, BOPP or PET. Able to work in highly customer focused laboratory settings. Proficient in DOE and able to work with R&D management workflow software. Ability to work in 5S and safe environment. Displays good verbal and written skills. What WE Can Do For You Penn Color offers many tangible and intangible benefits to our full time employees: Tangible benefits include: Highly competitive compensation A choice between 3 outstanding medical plans 401K with a strong company match PTO to balance your life Additional company perks And More! Our intangible benefits really set us apart: Unmatched company stability Long-term career opportunity True open door, friendly environment Ability to "own" your role Company events that bring us all together If you desire a long-term career, want to work alongside an exceptional group of people, and wish to use your talents to shape a world-class company, then we are your employer of choice! Together, we will illuminate the world! Penn Color, Inc. is an Equal Employment Opportunity employer. We adhere to a policy of making employment decisions without regards to race, color, religion, sex, age, disability or any other protected categories. It is our intention that all qualified applicants be given an equal opportunity and that selection decisions be based on job-related factors.
    $82k-111k yearly est. Auto-Apply 60d+ ago
  • Biology - Imaging R&D

    Eli Lilly and Company 4.6company rating

    Principal research scientist job in Philadelphia, PA

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Position Overview:Eli Lilly and Company (Lilly) Imaging Research and Development provides technical expertise for molecular and anatomical imaging to Lilly Research Laboratories. The Biologist will provide histopathology support by assisting in human tissue labeling to establish well-characterized tissue panels for compound screening and pathophysiological evaluation of target expression towards the discovery of new PET tracers for evaluation as development candidates.Responsibilities:• Design, develop, and execute human brain tissue characterization protocols (sample preparation and cryosectioning, staining, immunohistochemistry and autoradiography) for neuroscience research and imaging biomarker projects.• Assist in organization of tissue staining data from various research projects• Conduct and design radioligand binding assays such as autoradiography.• Implement digital pathology tools compatible with whole slide imaging scanner, autoradiography and confocal microscopy.Basic Qualifications:• Master of science degree, preferentially in Neuroscience with a minimum of 1 year experience in PET tracer discovery.Additional Skills/Preferences:Proficiency in immunohistochemistry, including immunofluorescence, automated histology equipment, spatial omics platform, gene silencing knowledge, and morphometry image analysis software (Visiopharm).• Provide strategic and technical expertise on the design and optimization of protein and transcript target detection.• Develop morphometric quantitative analysis methods using AI/ML software for target mapping in human samples• Experience in rodent and human tissue preparation and handling• Evaluation of small molecules and biologicals• Ensure good laboratory practice for data documentation as well as communicate research findings and recommendations to internal and external stakeholders through written reports, oral presentations and scientific communications.• In-depth knowledge of rodent and human neuroanatomy• Understanding of neuropathological hallmarks scoring• Use of real-time autoradiography is preferred• Ability to be pro-active, flexible, and capable of independent trouble shooting and problem solving. Work within a team-oriented lab environment and work within cross-functional project teams• Participate in scientific conferences and workshops to continue education/professional development• Good organizational and time-management skills• Excellent written and verbal communication skills Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 - $169,400 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly
    $65.3k-169.4k yearly Auto-Apply 1d ago
  • Senior Scientist, Formulations

    8427-Janssen Cilag Manufacturing Legal Entity

    Principal research scientist job in Malvern, PA

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D Job Category: Scientific/Technology All Job Posting Locations: Malvern, Pennsylvania, United States of America Job Description: We are searching for the best talent for our Senior Scientist, Formulations located in Malvern, PA. About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine Purpose: The Sr. Scientist, Formulations will join a highly motivated team working within Drug Product Development & Delivery, and be responsible for leading and supporting the development of protein biotherapeutic drug products and delivery strategies as part of the broader CMC function. You will be responsible for: Devise and implement formulation and drug product presentation strategies to support all phases of clinical and commercial development Lead protein programs as a scientific integrator in early development Support late phase protein programs by leading formulation activities Design and execute studies to characterize, optimize, and demonstrate the stability of protein formulations Provide subject matter expertise in interactions with health authorities, including authoring IND granules, participating in meetings, and responding to questions Qualifications/Requirements: Education: PharmD or PhD with 0-3 years (or BS or MS with >3 years) of clinical or industry experience is required. Pharmaceutical industry experience preferred. Experience and Skills: Required: Knowledge of and experience with protein biophysical characterizations techniques Experience interpreting and analyzing data from biophysical and biochemical assays and designing appropriate experiments Familiarity with clinical practices and compendial guidance for preparation and administration of parenteral drug products in the clinical trial and commercial setting Ability to innovate and use emerging developments in relevant scientific fields to support new technical and research initiatives Technical writing skills, including the ability to maintain high quality documentation and prepare SOPs or other technical reports Communication and collaboration skills to both lead and work with teams Capability to learn and navigate problems with a high degree of independence Preferred: Understanding of regulatory pathways for biotherapeutics; experience with authoring and reviewing regulatory filings (e.g. IND, IMPD, BLA, MAA) Publication and presentation history and involvement with scientific or clinical organizations or conferences Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via *******************/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. #LI-Hybrid Required Skills: Preferred Skills:
    $80k-115k yearly est. Auto-Apply 5d ago
  • Senior Quantitative Researcher Equities

    Stevens Worldwide Van Lines 3.9company rating

    Principal research scientist job in Radnor, PA

    SCM is committed to a workplace that values and promotes diversity, inclusion and equal employment opportunity by ensuring that all employees are valued, heard, engaged and involved at work and have full opportunities to collaborate, contribute and grow professionally. We are currently seeking a highly driven, well organized, and motivated candidate to join our team. SCM offers the opportunity to work in person, remotely or in a hybrid work environment. Primary Responsibilities: Develop, implement and evaluate quantitative trading models in the global equity markets. Continuously improve trading models and modeling techniques. Identify orthogonal factors to enhance overall portfolio performance. Requirements: 5+ years quantitative hedge fund or proprietary trading experience. Experience utilizing statistical modeling techniques to develop quantitative trading models. Keen focus on achieving outstanding risk adjusted returns. Strong interest in the financial markets. Exceptional economic intuition. Degree(s) in statistics, mathematics, computer science or other technical disciplines. The base pay for this position is anticipated to be between $150,000 and $300,000 per year. The anticipated annual base pay range is current as of the time this job post was generated. This position is eligible for other forms of compensation and benefits, such as a bonus, health and dental plans and 401(k) contributions, which includes a discretionary profit sharing program. An employee's bonus and related compensation benefits can be a significant portion of total compensation. Actual compensation for successful candidates will be carefully determined based on a number of factors, including their skills, qualifications and experience.
    $66k-89k yearly est. Auto-Apply 60d+ ago
  • Scientist II

    Artech Information System 4.8company rating

    Principal research scientist job in Fort Washington, PA

    LanceSoft is a nationally certified Minority Business Enterprise (MBE) that has established itself as a pioneer in providing highly scalable, cost-effective workforce solutions to a diverse set of customers across various industries in the United States. Headquartered in Virginia, LanceSoft currently operates out of several locations in the US and Canada. Title: Scientist II Location: Fort Washington, PA Duration: 12 Months Job Description: II. Position Summary: Provides testing, technical and troubleshooting support in the QC laboratories. These functions include: Collection, processing, method development and testing of chemical components, bulk products, raw materials, packaging components, finished products, marketed product stability, in-process materials, scale up, validation and cleaning validations to conform with specifications and standard operating procedures (SOPs). Thorough knowledge of SOPs, USP and other applicable pharmacopeia. Possess foresight to recognize task needs and performs the trained task without the request of management. Reviews and/or writes the following documents: APR, SOPs, QSRs, Instrument qualification, protocol/report writing, trending and review/analysis of data. Performs statistical analysis in support of APRs, Stability, and Product Release. Complies with cGMPs, safety training and regulations. Performs more advance technical projects under the supervision of management. Maintains an environment of respect and teamwork with all coworkers. The Company's management reserves the right to add, delete or otherwise alter assigned duties at any time. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. III. Responsibilities : (Define key accountabilities and/or activities.) Under limited supervision and in accordance with all applicable federal, state and local laws/regulations, the Companies' policies, procedures and guidelines, this position: Ensure quality and compliance in all my actions by: o Attend GMP training on the schedule designated for my role and as appropriate for my role o Adhere to strict compliance with procedures applicable to my role. o Exercise the highest level of integrity in the tasks that I perform o In a timely and prompt manner, identify report and seek correction for deviations noted in my workplace. o Embrace a behavior of employee involvement and commitment to doing the job right the first time Systems Knowledge • Be a Power User in the applicable systems and roles assigned. • Trained to the role in which you are assigned as required for your job function in the applicable systems • Utilize tools within MS office and other systems to improve business effectiveness • Exposure to & working knowledge of electronic batch records and/or other automated processes/systems (labs) • Working knowledge of SAP or ERP system; including other relevant systems per role • Working knowledge of an automated system. Product Knowledge • Understanding of product family, product size and put-up, and product characteristics (color, viscosity) associated active and excipient. Critical parameter associated with all processing steps. Training • Can act as SME and be a curriculum owner. • Partner with training department to create training materials including curricula. • Can act as qualified trainer in specific areas. • Participate in all trainings. • Ensure all trainings are completed on-time. Investigations • Assists in gathering information and documentation as required. • Participates in investigations as required. Compliance - Safety, GMP, Facilities • Provide support during regulatory inspections /audits as directed. Support may be in the form of scribes, runner, and document gathering. • Attend GMP training on the schedule designated for the role and as appropriate for the role. • May provide statistical analysis in support of the APR and Stability processes. • Adhering to strict compliance with procedures according to the roles and responsibilities. • Exercises the highest level of integrity in the tasks performed • In a timely and prompt manner, identify report and seek correction for deviations noted in the workplace. • Embrace a behavior of employee involvement and commitment to doing the job right the first time. • Strong working GMP knowledge. Communicates and identifies GMP gaps. • Can participate in all types of audits & Inspections. • Leads areas in ensuring all operations (processes) are completed in a compliant and safe manner. • Assists in coordination efforts in case of emergency- spill, fire etc. • Takes necessary action to eliminate and immediately address safety hazards. Communicate any observed unsafe behaviors immediately. • Understands the safety concerns and promotes a safety conscience culture for their job function. • Wears the appropriate PPE when working in manufacturing and other hazardous working environments and advocates standards of safety. • Contributes and attends all EHS programs as assigned. • Promptly communicates deficiencies to management. • Maintains facility and work area in good working condition. • Works with team to ensure all aspects of business remain compliant. Documentation Management • Edits documentation (i.e. Standard Operating Procedures, work instructions) as necessary. • Perform/assist in the completion and documentation of the process steps as per the documentation directives. • Complete visual verification of the process and document these steps in the appropriate system. • Document all activities per the GMP requirements. Process Excellence, Lean, Continuous Improvement, ME2 • Completes PE/ Lean awareness training. • Proactively identifies opportunities for continuous improvement and proposes actions to address these opportunities. • Participates and leads continuous improvement implementations and kaizen events. Understands and applies PE tools in daily work activities. Leadership • Job expert that less experienced personnel can go to for assistance. • Provides leadership in absence of supervisors (for short periods). • Assist management through change and transformation activities. • Facilitates departmental meetings and may assist in the coordination of other scheduled meetings. In absence of management, attends meetings on his/her behalf. • Continuously demonstrates all GLP values; specifically: integrity and credo based actions, self awareness and adaptability, results and performance driven, organization and talent development, and collaboration and teaming. Demonstrated behaviors include: fairness, honesty, consistent and ethical behaviors, empathy and collaboration. • Contributes and supports an environment that fosters diversity and inclusion. • Exhibits and lives core values and behaviors. • Contributes to a climate of open communication, engagement and ownership within team. • Builds working relationships • Provides feedback to site management • Supports strategic and tactical plans in alignment with site's mission and plans. IV. Requirements : Education: Bachelor's Degree in Microbiology, Chemistry, Biology, Natural Science, Medical Technology, or related science is required Experience: Minimum 2 years of GMP/GLP quality control lab experience in a pharmaceutical and/or OTC and/or regulated environment is required. Physical Demands: Capable of performing routine laboratory activities. Light to moderate lifting Knowledge, Skills and Abilities: Basic knowledge/exposure of a LIMS system is preferred Additional Information Regards, Anuj Mehta ************
    $70k-102k yearly est. 3h ago
  • Scientist

    Mindlance 4.6company rating

    Principal research scientist job in Spring House, PA

    Mindlance is a national recruiting company which partners with many of the leading employers in the Life Sciences, IT, and Financial Services sectors, feel free to check us out at ************************* Job Description The successful candidate will be responsible for performing multiple biochemical assays to screen compounds and profile lead candidates for pharmaceutical targets. Job requirements include ability to work with purified proteins, compound plate creation and tracking and perform biochemical assays. The successful candidate will work as part of an interactive research team; will report results of studies back to team members and in a timely, thorough, and coherent manner. Such a position requires an energetic, highly organized and motivated person. Requirements include compound plate creation using dispensers such as ECHO, compound ordering and tracking, execution of biochemical assays using automated liquid handlers and spectroscopic readers and generation of electronic notebooks that document all performed work. Good communication skills as well as an aptitude to perform research activities in a collaborative and result-driven setting are a must. Qualifications The successful candidate will possess an M.S. with 1-3 years of experience or a B.S. /B.A. with 2-4 years of experience or the equivalent training/experience. Additional Information All your information will be kept confidential according to EEO guidelines.
    $65k-93k yearly est. 3h ago
  • Associate Scientist - Biologics Discovery

    Insight Global

    Principal research scientist job in Spring House, PA

    Our large pharmaceutical clients is seeking an Associate Scientist to join their growing Biophysics & Molecular Attributes Group in Spring House, PA. The Biophysics & Molecular Attributes Group within Biologics Discovery uses innovative biophysical, biochemical, and mass spectrometry based analytical tools to help select best therapeutic candidates for clinical development. You will be a critical member of the Higher Order Structure (HOS) team that characterizes developability attributes like thermal stability, chemical stability, solubility, and aggregation on a broad range of biologics platforms including monoclonal antibodies, multi-specific antibodies, antibody drug conjugates, antibody radio conjugates, and other therapeutic proteins. You will design and perform experiments using a variety of technologies like HPLC, DSF, DSC, cIEF, GXII, DLS, and more. Key Responsibilities: Execute automated methods for biophysical and structural characterization of antibody therapeutics. Integrate robotic liquid handling systems (e.g., Hamilton, Tecan) with analytical platforms to improve efficiency, consistency, and sample throughput. Execute analytical analysis of biologics candidates using a wide variety of technologies such as size-exclusion HPLC, plate-based HIC/Heparin binding, DSF. Evaluate results to deliver scientifically supported conclusions and recommendations that are documented in appropriate technical reports. Maintain lab and equipment. Collaborate with colleagues in the global organization to support discovery projects. Assist in developing recommendations for improving standard procedures. Qualifications: Master's or Bachelor's Degree in a related field of study Minimum of 1 year of protein/antibody analytical methods experience Experience using HPLC, DSF or DLS Salary: $70,000-$75,000 (flexible based on experience) Hours: Monday-Friday, 8:00am-5:00pm Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year PTO: 10 PTO days, 6 paid sick days annually & paid Holidays Benefits: Medical, Dental, Vision and 401K plans available Exact compensation may vary based on several factors, including skills, experience, and education. Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.
    $70k-75k yearly 4d ago
  • Scientist - Imaging Research and Development

    Eli Lilly and Company 4.6company rating

    Principal research scientist job in Philadelphia, PA

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Organization Overview: At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. Responsibilities: Lilly Imaging/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The scientist will provide expertise for biological assay development for the discovery and characterization of novel PET imaging agents, with a focus on neuroscience or oncology imaging and other therapeutic areas. This scientist will work independently, coordinating experimental details of internal and external partnered projects, conducting experiments him/herself, performing data analysis, and presenting data to internal teams and the international scientific community. Establish and execute imaging research projects supporting oncology, neuroscience or other drug discovery and biomarker projects Design and conduct novel binding assays, including radioligand binding assays Characterize and purify biological targets Collaborate with internal project teams, implement translatable imaging biomarker assays and ensure seamless translation of projects Publish results of research projects as appropriate Participate in extramural scientific organizations and attend scientific symposia as well as workshops in order to continue educational/professional development Other duties as assigned Basic Requirements: Degree in physical or biological sciences or imaging-related field Bachelor's degree with min of 10 years' experience or master's with a min of 8 years' experience in scientific field Experience with in vitro assay development Additional Skills/Preferences: Experience with in vitro assay development Experience in Oncology or Neuroscience, preferably in molecular imaging Experience designing and executing novel biochemical, cellular and tissue assays, including radioligand binding assays (e.g. filtration binding, ELISA/AlphaLISA, SPR and LC/MS) Experience working with amyloidogenic proteins Demonstrated ability to independently conceive, design and execute the characterization and purification of biological targets Experience in drug discovery of PET molecular imaging agents Peer reviewed publications Willingness/desire to learn and incorporate additional technologies or therapeutic area biology to address imaging needs Peer-reviewed publications Excellent communication skills (both written and verbal) Excellent presentation skills Strong organizational skills and ability to effectively manage multiple priorities Creativity and critical thinking skills Team Player Additional Information: Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $63,000 - $162,800 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly
    $63k-162.8k yearly Auto-Apply 30d ago
  • Senior Scientist, Analytical Research & Development

    Veranova L P

    Principal research scientist job in Paulsboro, NJ

    Job Description Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Sr. Scientist is responsible for the implementation, development, and validation of analytical test methods in support of process research, and cGMP production with emphasis on development of LC, GC, GC-MS and LC/MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc) methods for small molecules, ADCs, Oligonucleotides and Peptides Major support functions include sample analysis by various analytical techniques including HPLC, GC, LC-MS/MS, GC-MS, ICP-MS, CE, SEC-MALS, CE-SDS, cIEF, NMR, KF, titrations, and instrumental and wet chemical techniques. Other duties may involve analytical method modification, development, and validation. The incumbent may function as the primary contact on one or more development projects. In- depth involvement with the project team concerning the chemistry of the project and analytical chemistry needs is expected Core Responsibilities: Develop and validate new analytical procedures. Independently, detects and solves complex problems of high technical difficulty. Perform sample analysis using various analytical techniques (e.g., LC, GC, LC-MS, GC-MS, ICP-MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc.), interpret results, and prepare high-quality documentation such as protocols, analytical reports, and summary reports. Document all analyses per SOPs. Prepare SOPs, test methods, and other GMP documentation. Independently, detect and solve complex problems of high technical difficulty. Apply knowledge and expertise from multiple disciplines (including QA, QC, Analytical and production) to achieve project goals. Conduct investigations independently. Troubleshoot analyses and instruments. Support qualification of reference materials. Develop new analytical procedures. Validate analytical methods. Prepare and review scientific reports. Interface with internal and external clients. Qualifications: PhD in Analytical Chemistry or equivalent Minimum of 8 years' experience in a GMP environment. Minimum of 5 years' experience in method development and validation for small molecules Active Pharmaceutical Ingredients (APIs). Experience with Process Development of APIs. Experience with LC, GC, GC-MS, LC-MS, IC, spectroscopy, and wet chemistry. Experience mentoring staff members in an analytical department. Formal project management training. Experience with writing method validation protocols and reports desirable. Experience with Microsoft Office and other complex computer software (UPLC, Empower 3) desirable. Salary Range: $115,000 - $125,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice.
    $115k-125k yearly 27d ago
  • Scientist-I

    Artech Information System 4.8company rating

    Principal research scientist job in Spring House, PA

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description List major responsibilities and duties of the position. List most complex or difficult parts of job first. Describe scope of responsibilities. • Assist with activities as assigned by the the Clinical Scientist or Study Responsible Physician which support the monitoring and reporting of clinical trials . • Member of the clinical Work Group (WG) for each study assigned. • Assist with study-specific data review activities in support of database locks. • Support monthly medical monitoring data review activities. • Assist with tracking of safety events, review of new SAEs, and Narrative as appropriate. • Assist/Coordinate activities in support of external data requests • Other activities as determined by study team and phase of trial (ie start-up, execution or close out). PRINCIPAL RELATIONSHIPS: • Describe the primary working relationships (internal & external) and primary interfaces. • Clinical Team: SRP/SRSs, Clinical Scientist, MRP, GI-Derm/Immunology VP • Contacts Inside the Company: Integrated Data Services, Global Medical Safety, Global Clinical Operations, programming & biostatistics • Contacts Outside the Company: vendor and CRO/ARO contacts as appropriate • Internal J&J Use Only Revision Date: April 27, 2016 • Supervision: This position reports to Clinical Scientist/SRP Qualifications EDUCATION AND EXPERIENCE REQUIREMENTS: • Describe the minimum knowledge, skill and ability requirements for the position. Include any degrees or certifications which are required and/or desirable. • Bachelor's degree (or equivalent) required and 1-2 years relevant work experience preferred. • Bachelor's degree in a scientific displine or nursing preferred. Candidates with additional degrees such as Masters (or equivalent) will also be considered but not required. • Good organization skills, good written and verbal communication skills • Excellent independent time management skills • Proven ability to plan and track deliverables and timelines • Individual must work well in a dynamic environment and be able to prioritize and respond to changing needs of the business. • Proficient Microsoft Office applications and use of Internet, EXCEL, POWERPOINT, WORD Additional Information For more information, Please contact Sneha Shrivastava ************
    $70k-102k yearly est. 60d+ ago
  • Scientist - Protein Biophysical Analysis

    Insight Global

    Principal research scientist job in Spring House, PA

    Our large pharmaceutical client is seeking a Scientist for Protein Biophysical Analysis to join the growing Binding Group. This team focuses on developing and applying preclinical assays to support the discovery of therapeutic candidates. The ideal candidate will have strong expertise in biophysical and biochemical characterization, with a focus on affinity analysis methods. Key Responsibilities Conduct kinetics and affinity analysis of antigens and antibodies using SPR (Biacore, Proteon), BLI (Octet), and KinExA. Perform HPLC analyses to assess hydrophobicity, size, and purity of proteins. Characterize molecules using mass spectrometry (MS). Analyze data, document results, and maintain records in ELNs and LIMS. Maintain lab instruments, including cleaning spray sources, weekly calibration, and preparing calibration solutions. Support assay development, validation, and bioanalysis efforts as needed. Assist in drafting and executing peer-reviewed posters, manuscripts, technical reports, and patent filings. Required Skills & Experience Bachelor's degree in a related field (advanced degree preferred). Hands-on experience with biophysical binding analysis methods, such as: Biacore, LSA, SPR methods (Proteon), BLI (Octet), KinExA Fluorescence anisotropy, RIA, or flow cytometry for affinity determination Solid understanding of protein biochemistry, binding affinity, thermodynamics, and antibody structure. Pharmaceutical experience with mass spectrometry characterization of antibodies (preferred).
    $58k-87k yearly est. 4d ago
  • Scientist - Imaging Research and Development

    Eli Lilly and Company 4.6company rating

    Principal research scientist job in Philadelphia, PA

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. Organization Overview: At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. Responsibilities: Lilly Imaging/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The scientist will provide expertise for biological assay development for the discovery and characterization of novel PET imaging agents, with a focus on neuroscience or oncology imaging and other therapeutic areas. This scientist will work independently, coordinating experimental details of internal and external partnered projects, conducting experiments him/herself, performing data analysis, and presenting data to internal teams and the international scientific community. * Establish and execute imaging research projects supporting oncology, neuroscience or other drug discovery and biomarker projects * Design and conduct novel binding assays, including radioligand binding assays * Characterize and purify biological targets * Collaborate with internal project teams, implement translatable imaging biomarker assays and ensure seamless translation of projects * Publish results of research projects as appropriate * Participate in extramural scientific organizations and attend scientific symposia as well as workshops in order to continue educational/professional development * Other duties as assigned Basic Requirements: * Degree in physical or biological sciences or imaging-related field * Bachelor's degree with min of 10 years' experience or master's with a min of 8 years' experience in scientific field * Experience with in vitro assay development Additional Skills/Preferences: * Experience with in vitro assay development * Experience in Oncology or Neuroscience, preferably in molecular imaging * Experience designing and executing novel biochemical, cellular and tissue assays, including radioligand binding assays (e.g. filtration binding, ELISA/AlphaLISA, SPR and LC/MS) * Experience working with amyloidogenic proteins * Demonstrated ability to independently conceive, design and execute the characterization and purification of biological targets * Experience in drug discovery of PET molecular imaging agents * Peer reviewed publications * Willingness/desire to learn and incorporate additional technologies or therapeutic area biology to address imaging needs * Peer-reviewed publications * Excellent communication skills (both written and verbal) * Excellent presentation skills * Strong organizational skills and ability to effectively manage multiple priorities * Creativity and critical thinking skills * Team Player Additional Information: * Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status * Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $63,000 - $162,800 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly
    $63k-162.8k yearly Auto-Apply 60d+ ago
  • Scientist - II

    Artech Information System 4.8company rating

    Principal research scientist job in Spring House, PA

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description: • Working within the Prostate/IO drug discovery team to execute in vitro and ex vivo experiments to be used for compound candidate selection and to explore the therapeutic potential of drug targets. • Contribute to development, optimization and troubleshooting of immunological-based assays • Works with minimal supervision on projects of moderate to complex scope • Uses good verbal communication skills and interpersonal skills to communicate with other team members Other duties include data analyses, maintain electronic notebook records of experimental data, summarize and communicate results in internal meetings Must have experience in: • Flow cytometry techniques and flow cytometry analysis. Multicolor flow cytometry experience is strongly desirable.\ • Basic aseptic cell culture technique, such as maintaining cell lines and primary cells, cell banking, etc . • Basic skills in molecular biology including transfection and viral transduction, DNA isolation, cloning, etc . • Experience with cell-based immunoassays, and working with primary cells and ex- vivo analyses is desired . • Familiarity with basic cell purification techniques and immunological phenotyping procedures, as well as processing blood and primary human and rodent tissues, is also desired Demonstrated creativity and Client approaches to solving technical problems • Strong organizational skills including the ability to manage several projects simultaneously • Excellent interpersonal skills with the ability to interact effectively with people, internally and externally Methodical, reliable and comfortable working under fixed timelines Detail-oriented, with excellent record-keeping skills Qualifications Requirements: BA/BS or MA/MS degree in immunology, pharmacology, molecular biology, cancer biology, or related field. 2-5 years of experience (MS/MA) or 2-8 years (BA/BS) years of experience, performing progressively advanced duties at the Associate Scientist I level, or the equivalent training/experience Additional Information Best Regards, Sneha Shrivastava ************
    $70k-102k yearly est. 60d+ ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Lower Merion, PA?

The average principal research scientist in Lower Merion, PA earns between $78,000 and $158,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Lower Merion, PA

$111,000
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