Principal research scientist jobs in Manassas, VA

. You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate. Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; leads or actively participates in portfolio- and enterprise level workgroups aimed at optimizing PFE clinical development procedures; may be a subject matter expert or business process owner for a relevant SOP or procedure. MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval Excellent knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations Extensive understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance Experience working on large data sets Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery Experience leveraging a variety of communication tools and techniques to communicate results Experience solving problems collaboratively and handling conflict constructively Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations Experience working proactively and independently, organizing tasks, time and priorities of self and others Experience building partnerships across the company to achieve the needs of the program PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. both as a leader and a key contributor Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

Full-time Description Granules Pharmaceuticals, Inc., is seeking a detail-oriented and scientifically driven Sr. Scientist to join our team in the area of Analytical Method Development and Validation. The ideal candidate will possess strong expertise in developing and validating analytical methods for assay, related compounds, residual solvents, dissolution, and particle size analysis. Proficiency in Mass Spectroscopy and peptide testing is essential, with experience in bioassay methodologies considered a plus. This role requires a solid understanding of scientific principles to troubleshoot and solve analytical challenges, as well as experience in drafting and reviewing method validation protocols and reports in compliance with SOPs and regulatory guidelines. Strong communication skills and the ability to interpret technical procedures, FDA guidance documents, and scientific literature are essential for success in this role. JOB DUTIES & RESPONSIBILITIES include but not limited to: With minimal supervision, perform the analytical method development and method validation for dissolution, assay, and related compounds of raw material and finished products. Develops and validates methods to determine purity, potency, identity, residuals, and characterization of peptide products. Ability to individually work on development and validation for Reversed-Phase, Ion Exchange, and Size Exclusion chromatography using UPLC/HPLC/MS. Draft the analytical method validation protocols and reports Performs testing pharmaceutical raw materials, bulk and finished products, scale-up samples, process validation samples, cleaning verification/validation samples, and stability samples to support formulation development. Responsible for the timely and accurate execution of lab analysis. Independently compile the analytical data, make sound judgment of the data and interpret the data, and notify the results to manager/Director. Maintaining full compliance with all applicable US FDA - cGMP regulations and internal SOPs. Maintain laboratory notebooks and records of all the raw data as per Good Documentation Practices. Assists with training other junior members of the analytical development team as needed Maintain individual training records. Follow safety procedures and practices. Maintain a clean, orderly work environment. Works with computer-controlled equipment and processes. Performs other work-related duties as assigned Perform in-vitro dissolution testing for in-process, finished product and stability samples. Execute method transfer activities for raw materials and finished dosage forms. Ensures compliance with SOPs, policies and procedures required by the Company and regulatory agencies. Document experiments accurately and complete all associated documents (Instrument, Standard and Column usage logbooks) in compliance with internal SOPs and FDA guidelines. Evaluate test results against standards and timely reporting of any deviations, OOS, OOT and atypical results to the supervisor/department head. Other duties assigned by management based on requirements. Management Responsibility Assign daily work schedule in timely manner Provide Suggestions in method Development and validation. Interpret and review generated results Provide assistance in professional development. Reports to: Manager Analytical R&D Requirements Knowledge & Skills: Hands-on experience in Dissolution, HPLC, LC-MSGC, UV, FTIR, and other laboratory instruments. Experience with a wide variety of software and information systems (e.g. Empower, Microsoft word and Excel). Strong knowledge in analytical method development and validation under cGMP environment and experience in problem-solving skills and instrument troubleshooting. Good oral and written communication skills and the ability to write and review technical report Proven Knowledge of the major analytical techniques and operation of instruments such as HPLC, GC, dissolution, FT-IR, UV-VIS Spectrophotometer, Particle size analysis (Malvern Mastersizer, Sonic sifting and Sieve shaker), Karl Fisher Instrument, Potentiometric Titration, Density meter, pH meter, Melting point apparatus, Analytical Balances, Viscometer Proficient in documentation as per Good Documentation Practice Computer skills including Microsoft and Excel Excellent verbal and written communication and skills Experience & Education: Bachelor's degree in Analytical Chemistry or Chemistry or related field with 4+ years or MS/PhD with 2+ years of GMP and GLP-related pharmaceutical industry experience in Peptide and small molecule solid oral formulation analytical development. Knowledge of Good Manufacturing Practices (cGMP) Experience with software and information systems (e.g. Empower, Microsoft word and Excel) Physical Requirements/Working Environment Must be able to stand for long periods of time (up to 12-hour shifts), maneuver at least 40 pounds, wear a respirator and pass associated respirator tests and/or requirements, and be able to wear all required PPE. Vision - ability to see details at close range (within a few feet of the observer). Physical Requirements/Working Environment: Must be able to stand for long periods of time (up to 12-hour shifts), maneuver at least 40 pounds, wear a respirator and pass associated respirator tests and/or requirements, and be able to wear all required PPE. Vision - ability to see details at close range (within a few feet of the observer). Disclaimer: The above information on this description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.

Granules Pharmaceuticals, Inc., is seeking a detail-oriented and scientifically driven Sr. Scientist to join our team in the area of Analytical Method Development and Validation. The ideal candidate will possess strong expertise in developing and validating analytical methods for assay, related compounds, residual solvents, dissolution, and particle size analysis. Proficiency in Mass Spectroscopy and peptide testing is essential, with experience in bioassay methodologies considered a plus. This role requires a solid understanding of scientific principles to troubleshoot and solve analytical challenges, as well as experience in drafting and reviewing method validation protocols and reports in compliance with SOPs and regulatory guidelines. Strong communication skills and the ability to interpret technical procedures, FDA guidance documents, and scientific literature are essential for success in this role. JOB DUTIES & RESPONSIBILITIES include but not limited to: With minimal supervision, perform the analytical method development and method validation for dissolution, assay, and related compounds of raw material and finished products. Develops and validates methods to determine purity, potency, identity, residuals, and characterization of peptide products. Ability to individually work on development and validation for Reversed-Phase, Ion Exchange, and Size Exclusion chromatography using UPLC/HPLC/MS. Draft the analytical method validation protocols and reports Performs testing pharmaceutical raw materials, bulk and finished products, scale-up samples, process validation samples, cleaning verification/validation samples, and stability samples to support formulation development. Responsible for the timely and accurate execution of lab analysis. Independently compile the analytical data, make sound judgment of the data and interpret the data, and notify the results to manager/Director. Maintaining full compliance with all applicable US FDA - cGMP regulations and internal SOPs. Maintain laboratory notebooks and records of all the raw data as per Good Documentation Practices. Assists with training other junior members of the analytical development team as needed Maintain individual training records. Follow safety procedures and practices. Maintain a clean, orderly work environment. Works with computer-controlled equipment and processes. Performs other work-related duties as assigned Perform in-vitro dissolution testing for in-process, finished product and stability samples. Execute method transfer activities for raw materials and finished dosage forms. Ensures compliance with SOPs, policies and procedures required by the Company and regulatory agencies. Document experiments accurately and complete all associated documents (Instrument, Standard and Column usage logbooks) in compliance with internal SOPs and FDA guidelines. Evaluate test results against standards and timely reporting of any deviations, OOS, OOT and atypical results to the supervisor/department head. Other duties assigned by management based on requirements. Management Responsibility Assign daily work schedule in timely manner Provide Suggestions in method Development and validation. Interpret and review generated results Provide assistance in professional development. Reports to: Manager Analytical R&D Requirements Knowledge & Skills: Hands-on experience in Dissolution, HPLC, LC-MSGC, UV, FTIR, and other laboratory instruments. Experience with a wide variety of software and information systems (e.g. Empower, Microsoft word and Excel). Strong knowledge in analytical method development and validation under cGMP environment and experience in problem-solving skills and instrument troubleshooting. Good oral and written communication skills and the ability to write and review technical report Proven Knowledge of the major analytical techniques and operation of instruments such as HPLC, GC, dissolution, FT-IR, UV-VIS Spectrophotometer, Particle size analysis (Malvern Mastersizer, Sonic sifting and Sieve shaker), Karl Fisher Instrument, Potentiometric Titration, Density meter, pH meter, Melting point apparatus, Analytical Balances, Viscometer Proficient in documentation as per Good Documentation Practice Computer skills including Microsoft and Excel Excellent verbal and written communication and skills Experience & Education: Bachelor's degree in Analytical Chemistry or Chemistry or related field with 4+ years or MS/PhD with 2+ years of GMP and GLP-related pharmaceutical industry experience in Peptide and small molecule solid oral formulation analytical development. Knowledge of Good Manufacturing Practices (cGMP) Experience with software and information systems (e.g. Empower, Microsoft word and Excel) Physical Requirements/Working Environment Must be able to stand for long periods of time (up to 12-hour shifts), maneuver at least 40 pounds, wear a respirator and pass associated respirator tests and/or requirements, and be able to wear all required PPE. Vision - ability to see details at close range (within a few feet of the observer). Physical Requirements/Working Environment: Must be able to stand for long periods of time (up to 12-hour shifts), maneuver at least 40 pounds, wear a respirator and pass associated respirator tests and/or requirements, and be able to wear all required PPE. Vision - ability to see details at close range (within a few feet of the observer). Disclaimer: The above information on this description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.

Come join our family! Microbac Laboratories is an essential business offering competitive pay and benefits including medical, dental, vision, life insurance, disability, generous paid time off including vacation, holidays and flex-time, a wellness program, referral bonus, tuition reimbursement and more! Whether you are just starting your career in science or looking to further it, Microbac will put you on the path of an exciting career with room to grow. Quality, safety, giving back to our communities, diversity and inclusion, customer success and employee wellbeing are part of our core culture. We are looking for motivated individuals to join our family as an Associate Scientist I . ABOUT MICROBAC Microbac Laboratories, Inc. is a premier commercial laboratory testing firm that partners with clients worldwide, offering laboratory solutions to the life science, food and nutrition, and environmental industries and serves our clients with the utmost expertise and respect for their market requirements, constraints, and challenges. We embody a company-wide commitment to exceptional customer experience, which has been refined over nearly 50 years of trusted, analytical and measurement experience. Through our network of laboratories, offices, and field services, we have the flexibility to meet the unique requirements for each client, project, and scope. As a privately held third-party testing company, Microbac operates with a commitment to safety, quality, and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and nutrition and life science markets. JOB SUMMARY The Associate Scientist I, working in an accredited commercial laboratory, is responsible for assisting with the conduct of microbiological assays and associated activities to determine antimicrobial efficacy of household and commercial cleaning products. ESSENTIAL FUNCTIONS: Following established SOP's and adhering to state, federal and other accrediting body requirements, collect information about the antimicrobial properties of substances/samples to support the analytical testing needs of our clients for such purposes as quantitative or qualitative analysis, and product development Perform laboratory housekeeping duties to include autoclaving and glassware processing Prepare necessary standards, solutions, reagents, media, etc., required for sample analyses Perform equipment and instrumentation set up Operate basic and specialized laboratory instrumentation Prepare and analyze samples Accurately record observations and data and interpret results Assists in the development and validation of new analytical methods Assists in the development of new laboratory procedures Assist department supervisors and managers with staff training Sign off on final certificates of analysis Contribute to writing, editing, and reviewing SOP's Monitor and address sample backlog issues Perform peer review of data to ensure accuracy Maintain accurate, up to date logs, notebooks, and equipment records Perform necessary laboratory administrative functions such as filing paperwork, photocopying, reviewing of data, and entering data into computerized LIMS Comply with and promote Personnel, Safety, and Quality Program MINIMUM REQUIREMENTS: Bachelor's degree from a four-year accredited institution in a related field of applied science Prior analytical testing experience Above average knowledge of principles, terminology, practices, techniques, and instrumentation commonly used in a laboratory setting Ability to interpret data and prepare reports Ability to effectively prioritize work and manage time to meet deadlines and rush orders Computer literacy Ability to work with delicate laboratory equipment Ability to communicate effectively in both written and verbal formats WORKING CONDITIONS AND PHYSICAL REQUIREMENTS: The physical demands and working conditions described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Physical Requirements: While performing the duties of this job, the employee is regularly required to use hands to finger, handle, or feel objects, tools; talk or hear. The employee is required to stand, walk, and sit. The employee must regularly lift and/or move up to 25 pounds. Specific vision abilities required by this job include color vision and depth perception. Working Conditions: While performing the duties of this job, the employee will be in a general laboratory and office environment. The noise level in the work environment is usually moderate. This job may require travel less than 20% As a privately held third-party testing company, Microbac operates with a commitment to safety, quality and compliance. Our diverse work portfolio includes broad accreditation offerings and tested insights across the environmental, food and life science markets. OTHER: This is not an exhaustive list of all duties an employee may be required to perform. Microbac reserves the right to revise the job description at any time. Employment is at-will. Microbac, promotes a drug-free, alcohol-free workplace. Applicants considered for hire must pass a drug test before beginning work. Refusal to submit to testing will result in disqualification of further employment consideration. Microbac is an Equal Opportunity Employer - We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. All qualified applicants will receive consideration for employment.

About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site & Field Missions Travel: Some/Frequent (domestic campaigns, workshops) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $90,000 - $120,000 Job Description: The Support Scientist II will assist NASA scientists and engineers with advanced research tasks under the ATMOS contract. This includes instrument development, model evaluation, and analysis of atmospheric datasets. The role involves contributing to peer-reviewed publications and presenting results at conferences. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Conduct scientific analysis on atmospheric models and observational datasets. Provide operational support for instruments at GSFC and in the field. Collaborate with NASA scientists on mission planning and research goals. Publish findings in journals and present at scientific meetings. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements 2+ years of research experience in atmospheric or related sciences. Strong background in programming (FORTRAN, Python, C/C++). Familiarity with visualization/analysis tools such as IDL, MATLAB, or LabVIEW. Record of publications in peer-reviewed journals. Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or equivalent.

Fiber Laser Scientist Herndon, VA While working as a Fiber Laser Scientist at Fibertek, you will lead the design and development, integration, and test of advanced fiber laser systems typically with performance requirements beyond the state-of-the-art. Fibertek is a leader in the design, development, and delivery of advanced laser systems and technologies for military and aerospace applications. Your Job We are looking for and experienced and motivated fiber laser scientist or engineer to join a multi-disciplinary team and lead the design and demonstration of advanced laser systems. Example focus missions include space-based laser communications, lidar for tactical defense applications, earth-sensing lidar, and navigational lidars for planetary and docking missions. Fibertek's engineering teams simultaneously tackle laser optical performance beyond state-of-the-art while engineering systems for performance on challenging platforms with limited size, mass, and power and over stressing vibration, thermal, and/or radiation conditions. Delivered systems make a national impact to customers at NASA and throughout the defense community. The work-load will at times include multiple concurrent projects with a mix of short duration research programs and longer duration technology maturation programs resulting in a work culture that is team-oriented, intellectually stimulating, and consistently rewarding. Lead the engineering development of unique laser designs through modeling fiber laser performance, design analysis, component specification, and hardware assembly, integration, and test Coordinate and support the build, alignment, and performance characterization of fiber lasers including multi-stage amplifiers, phase & amplitude modulation implementation, spectral and coherent beam combining Coordinate and perform formal acceptance and qualification testing Participate in customer interactions including formal technical reviews Required Skills and Experience To exceed in this Fiber Laser Scientist role, you'll need the below expertise and experience: MS or PhD in Physics or Optical Engineering w/ a minimum of 5 years of direct hands-on fiber laser experience including designing, building, characterizing laser systems Knowledge of the laser theory and industry best practices associated with fiber laser systems including continuous wave lasers, pulsed, high peak power fiber, advanced fiber architectures, single-frequency injection locked lasers, low frequency noise lasers, electrical and thermal sub-systems. Expertise in laser physics of fiber lasers and amplifiers, including ytterbium, erbium, and/or thulium gain materials. Familiarity with relevant nonlinear processes and impacts to laser performance. Examples include Stimulated Brillouin Scattering, Four-Wave Mixing, Stimulated Raman Scattering, and Transverse Modulational Instability. Foundational understanding of fiber-optic components including types of fibers, pump lasers, couplers, modulators, isolators, mode-field adapters, polarization components, and others. Knowledge of tools for modeling fiber laser performance such as Matlab, RP Power Fiber or equivalent software Ability to design and execute experiments validating laser system performance and correlate the results with the expected performance Strong communication and documentation skills for efficient multidisciplinary communication US citizenship required Please apply today for this full-time Herndon-based Fiber Laser Scientist role and join the leader in the development of state-of-the-art laser and electro-optic solutions. Why Fibertek, Inc? At FIBERTEK, Inc. we pride ourselves in our innovation and customer success focused culture enabled by a creative and relaxed work environment with minimal bureaucracy. Fibertek fosters a progressive learning environment that values inspiration, promotes professional challenge and encourages personal growth. We offer a competitive and incentivized compensation package with excellent benefits. Fibertek, Inc. is an equal opportunity and affirmative action employer. Applicants are considered regardless of race, sex, gender identity, sexual orientation, religion, national origin, disability, protected Veteran status, age or any other protected characteristic in accordance with applicable law. If you need assistance or an accommodation for any part of the application process, please contact us by phone at ************ or via email at ***************.

Who We Are Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible. Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work. What Matters to Us Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team. Arcellx Core Values Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work. Think ‘we' before ‘me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals. Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right. How You'll Make a Difference As a Scientist , your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients. The “Fine Print” - What You'll Do Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies. Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed. Develop new methods, technologies and processes when necessary for project. Exercise significant technical discretion in the design, execution and interpretation of experiments. Communicate progress and project recommendations to team members. Skills and Experience We Look For BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience. Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis. Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation). Preference for experience in drug development, immunology or protein engineering. The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams. Rewards at Arcellx Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits. The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required. Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to **************** #LI-Onsite

Data Scientist Systems Integration, Inc. (SII) is a leading provider of customer experience, data analytics and digital transformation solutions. We are seeking a highly skilled Machine Learning Scientist to help the FBI uncover actionable insights from vast and complex data sets. This role focuses on identifying enterprise-level toolsets, applying advanced data mining techniques, and building predictive models that integrate with FBI systems. The ideal candidate will be a strategic thinker with deep technical expertise and the ability to communicate findings clearly across all levels of the organization. Responsibilities: * Select, build, and optimize machine learning classifiers using advanced techniques * Apply state-of-the-art data mining methods to extract meaningful patterns * Enhance data collection procedures to ensure relevance for analytic systems * Cleanse, process, and validate data integrity for analysis * Conduct ad-hoc analyses and present results in a clear, actionable format * Develop and monitor automated anomaly detection systems * Design innovative approaches for handling and analyzing large-scale data sets * Address fundamental challenges in data handling, search, and retention * Solve complex data storage and retrieval issues * Develop software solutions to improve data search and access processes * Analyze results and deliver recommendations that support mission objectives. Qualifications: * Must be US Citizen * Requires a Top-Secret clearance (SCI Poly may be required later). * Strong understanding of machine learning algorithms (e.g., kNN, Naive Bayes, SVM, Decision Forests) * Proficiency with data science toolkits such as R, Weka, NumPy, and MATLAB * Excellent communication and presentation skills * Experience with tools like Microsoft Power BI, Anaconda, and SPSS * Skilled in data visualization using D3.js, GGplot, or similar platforms * Proficient in SQL and Hive for querying large datasets * Experience with NoSQL databases (e.g., MongoDB, Cassandra, HBase) * Solid foundation in applied statistics (distributions, testing, regression) * Strong scripting and programming capabilities. * Minimum 5 years of experience supporting data-driven projects of similar scope. * Bachelor's degree required in data science, statistics, computer science or related field.

Department: College of Science Classification: Research Staff 12-month Job Category: Research Staff Job Type: Full-Time Work Schedule: Full-time (1.0 FTE, 40 hrs/wk) Workplace Type: Hybrid Eligible Sponsorship Eligibility: Not eligible for visa sponsorship Salary: Salary commensurate with education and experience Restricted: Yes Criminal Background Check: Yes About the Department: The Center for Collision Safety and Analysis (CCSA) at George Mason University brings together a strong and richly experienced team of scientists and engineers focused on using advanced technology to understand collisions involving transport vehicles and to develop means to avoid or mitigate them to enhance safety and security. CCSA is associated with the College of Science at George Mason University. The mission of the Center for Collision Safety and Analysis is to advance collision safety though scientific research using sophisticated computational methods that provide a means to establish a sounder understanding of collision dynamics, likely effects on the users, vehicles, and infrastructure system elements, and potential effectiveness of mitigation options. In addition to the scientific and engineering activities, the operation of CCSA includes interactions with federal government agencies, the National Academy of Science, industrial research sponsors, and other educational and research institutes/universities, as well as other units (colleges and research centers) within Mason. CCSA also operates an experimental facility, the Federal Outdoor Impact Laboratory (FOIL), at the US Department of Transportation. George Mason University College of Science (Mason Science) is committed to advancing inclusive excellence and fostering an environment free from discrimination, harassment, and retaliation throughout our STEM community. At Mason Science, our values include cultivating an organizational culture that promotes belonging, respect, and civility. We believe that varied opinions, cultures, and perspectives are what provides vibrancy, innovation and growth to an academic community. By prioritizing cultural responsiveness in academics, teaching, research, and global engagement, we strive to attract faculty and staff who exemplify the Mason Science mission and vision. About the Position: The Research Scientist provides the additional needed support to the department to conduct sponsored research projects. The position is responsible for conducting sponsored research in transportation safety, developing material and computer simulation models, developing vehicle and roadside hardware models, and carrying out simulation analysis for vehicle and highway safety for vehicle applications. Responsibilities: * Develops Finite Element (FE) models in the Vehicle Digitizing Lab; * Performs the validation and verification of FE vehicle models; * Conducts simulations of various regulatory crash modes to improve the validity of FE models.; * Carries out sponsored research related to simulations, design optimization, material model development, new design concepts and improvement, etc.; * Develops advanced material models, such as metals, composites, concrete, soil, wood etc., using user-define subroutines for crash and impact applications; * Performs biomechanics analysis in crash-related simulations using Anthropomorphic Test Device (ATD) and Human Body Model (HBM) dummies to study potential injury risks and preventative measures; and * Builds, maintains, and analyzes databases of crash tests, simulations, real-world accidents, and other related resources to understand accident trends and causes, injury mechanism, safety measures, etc. using Artificial Intelligent (AL) and Machine Learning (ML) techniques. Required Qualifications: * Bachelor's degree in related field, or the equivalent combination of education and experience; * Experience in transportation safety, developing material and computer simulation models, developing vehicle and roadside hardware models, and carrying out simulation analysis for vehicle and highway safety for vehicle applications; * Abilities in using Finite Element modeling and analysis; * Knowledge of injury biomechanics; * Knowledge of Artificial Intelligent (AL) and Machine Learning (ML) techniques; and * Abilities in user-defined material model development of CAE programs. Preferred Qualifications: * Master's degree in related field; * Over 5 years of experience in vehicle safety engineering for vehicle structure design and occupant safety and a background in Solid Mechanics; * Experience in statistical data analysis of crash-related databases (e.g. test data, simulation data, accident data, etc.); * Experience working in a collaborative team environment to develop creative solutions to complex challenges as well as the ability to work independently; * Good knowledge of transportation safety and testing standards (e.g. FMVSS, NCAP, IIHS, NCHRP, MASH, etc.) with the latest transportation safety research areas, concepts, practices, procedures, and problem-solving techniques; * Good skills with finite element pre- and post-processors (e.g., HyperMesh, LS-PrePost, ANSA, etc.); * Excellent abilities in creating crash simulations with occupants (ATD and HBM) and restraints, specifically using LS-DYNA; * Good skills with statistical data analysis and software (e.g. SAS); * Knowledgeable in the behavior, failure, and numerical models of solids such as metals, composite, soil, wood, and concrete; and * Good verbal and written communication skills, especially with technical reports and grant proposals. Instructions to Applicants: For full consideration, applicants must apply for Research Scientist at ********************** Complete and submit the online application to include three professional references with contact information, and provide a CV for review. Posting Open Date: December 8, 2025 For Full Consideration, Apply by: January 9, 2026 Open Until Filled: Yes

US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description • BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations. • This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data. • The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment. Qualifications Education: • Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field. Experience: • For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience. • For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience. Additional Information Special Skills/ Abilities • Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred. • Good documentation, writing and communication skills in a team based setting are essential.

Who We Are: A Mission Driven Company Novavax has a rich history of innovation to help eradicate disease, prevent serious illness and save lives. But there is still work to be done. Our people are passionate about the mission and vision that guide our work. We are seeking a highly motivated Scientist to join our growing Antibody Technologies team. The ideal candidate will have a strong background in immunology, oncology, and monoclonal antibody engineering, with additional experience in vaccine research and the application of AI/ML technologies to enhance target identification and antibody discovery. This role will contribute to the design, characterization, and advancement of next-generation vaccines. Key Responsibilities Design, execute, and troubleshoot experiments for discovery and engineering of monoclonal antibodies and immune-modulating biologics. Apply immunology expertise to evaluate biologic function, immune activation, tumor killing mechanisms, and vaccine-related responses. Leverage AI/ML tools for target evaluation, antibody optimization, library design, or developability prediction. Generate and interpret data from in vitro and ex vivo models (e.g., cell-based cytotoxicity assays, binding kinetics, immune cell profiling). Collaborate with cross-functional teams to advance vaccines into preclinical development. Communicate results to leadership and cross-functional teams; contribute to scientific publications, technical reports, and SOPs. Mentor junior scientists and contribute to a culture of innovation, scientific rigor, and teamwork Required Qualifications Ph.D. in Immunology, Cancer Biology, Molecular Biology, or related field, with 2+ years of postdoctoral experience (industry experience a plus). Demonstrated expertise in oncology biologics and monoclonal antibody discovery. Experience in vaccine immunology, innate/adaptive immune responses, antigen presentation, and immune-modulating biologics. Hands-on experience with cellular & molecular immunology techniques (e.g., ELISA, Western blot, SPR/BLI binding studies, Cytotoxicity and Viability Assays). Strong publication record in peer-reviewed journals and/or patent filings. Excellent communication, problem-solving, and project management skills. Preferred Qualifications Industry experience in biologics discovery, antibody engineering, or immuno-oncology. Familiarity with AI/ML approaches in biologics R&D (e.g., sequence-to-structure modeling, developability predictions, ML-driven antibody design) is preferred. Knowledge and experience with syngeneic mouse models. Experience and knowledge of NGS is preferred but not required. Experience working with CROs, academic partners, or biotech collaborations The annual base salary (or hourly wage) for this position falls within the range of $98,150.00 - $127,600.00. However, the actual base pay offered may vary based on several individualized factors, such as market location, job-related knowledge, skills, and experience. Novavax offers a base salary, annual bonus, equity grants, professional career development/growth opportunities, and a comprehensive benefits package including medical, dental, vision, Rx, STD, LTD, Life, Optional Life, 401(k) plan. Our Mission By leveraging our science, our technology and our people, we will innovate and collaborate to tackle the world's most significant health challenges. Our Vision We envision a world where our technology is amplified to touch the lives of billions, sparking transformation in global health. Our Values Integrity, Collaboration, Innovation, Agility and Accountability sit at the heart of our culture. They express the mindset and behaviors that guide how we show up, how we work together and how we create impact - for patients, partners and each other. Our Footprint Novavax is proudly headquartered in the USA with main offices in Gaithersburg, Maryland. We conduct R&D and manufacturing for our Matrix-M adjuvant in Uppsala, Sweden.

Sr Bioinformatics Scientist - (25000388) Description The Senior Bioinformatics Scientist, serving as Assistant Director of the BTI Bioinformatics Core, is a leadership-level role requiring a Ph. D. in a biological or computational discipline and 8-15 years of relevant experience (inclusive of doctoral work). Reporting to the Director of the BTI Bioinformatics Core, this position provides scientific and technical leadership as the Core's primary “go-to” expert for methodological guidance, code standards, QC frameworks, and pipeline development, while mentoring Bioinformatics Scientists and supporting Core infrastructure. The role is split between 50% scientific oversight, project guidance, and code review and 50% hands-on computational biology analyses for the Rare Brain Tumor Program. The ideal candidate demonstrates deep technical expertise, collaborative leadership, and a commitment to open, reproducible science, with substantial pediatric oncology genomics experience, strong biological insight, and the ability to both embrace learning CNS tumor biology and guide the computational direction of multiple PIs' research programs. Qualifications Minimum EducationDoctor of Philosophy (Ph. D. ) Biological or computational discipline (Required) Minimum Work Experience8 years 8-15 years in applied bioinformatics, genomics, and computational work (can be inclusive of relevant computational Ph. D. dissertation years) (Required) Required Skills/KnowledgeTechnical Skills• Advanced proficiency in UNIX/Linux environments. • Expert-level programming and data analysis skills in R, Python, or equivalent. • Deep experience with NGS, microarray, multi-omics, and other high-throughput platforms and their application to specific biological questions. • Expertise with a broad range of bioinformatics tools, pipelines, and genomic databases, such as GATK, UCSC Genome Browser, Bioconductor, ENCODE, NCBI, Kids First, gnom AD, ClinVar, OMIM, HGMD, and COSMIC. • Demonstrated expertise in GitHub, containerization (Docker, Podman, and/or Singularity), and workflow automation. • Strong grasp of workflow management tools (e. g. , Snakemake, Nextflow, WDL, CWL). • Expertise using high-performance computing (HPC) environments and/or cloud platforms (e. g. , AWS, Google Cloud) for large-scale analyses. • Ability to develop user-facing bioinformatics applications using tools such as RShiny or Python Streamlit. Scientific & Analytical Skills• Demonstrated ability to design and execute robust statistical analyses across diverse genomic and proteomic data types. • Deep expertise interpreting and visualizing results in biological or clinical contexts. • Deep domain expertise in at least one disease area or biological system through publications, pipelines, tools, and/or open-source contributions. • Experience writing scientific manuscripts, figure and methods development, and manuscript authorship. Collaborative and Professional Skills• Ability to lead complex interdisciplinary projects and guide teams from analysis to publication. • Strong mentorship skills and demonstrated ability to train junior scientists and analysts. • Excellent organizational, communication, and presentation skills. • Proven ability to interact effectively with investigators, clinicians, laboratory staff, peers, and institutional leadership. • Commitment to open and team science practices, including transparency, reproducibility, shared documentation, and collaborative problem-solving. • Familiarity with project management tools and methodologies such as Scrum, Agile, Jira, GitHub Projects, Trello, or Asana to coordinate timelines, tasks, and deliverables across teams. Functional AccountabilitiesResponsible Conduct of Research (RCR) Uphold the highest ethical standards and integrity in all scientific activities. Ensure data privacy and patient confidentiality standards. Maintain reproducibility and transparency in code, workflows, and documentation. Properly cite software tools, data sources, and collaborators. Comply with institutional policies and federal regulations governing research and data use. Bioinformatics Analysis & Method DevelopmentLead the development and implementation of novel and optimized workflows for large-scale -omic datasets. Design rigorous statistical frameworks that align with study goals and clinical hypotheses. Collaborate with investigators to determine the most effective computational approaches to complex problems with biological context. Contribute significantly to high-impact publications and grant proposals. Technical Oversight & TroubleshootingResolve advanced, multi-layered bioinformatics and workflow issues independently. Design scalable, sustainable solutions to recurring analysis or infrastructure challenges. Serve as technical advisor to junior bioinformatics staff, providing design, optimization, and troubleshooting support. Scientific Communication & Grant SupportLead preparation of figures, written analysis, and supplemental methods for manuscripts, grants, and collaborators. Clearly present findings and strategy in lab/collaborator meetings, present journal clubs, and attend scientific conferences. Provide strategic guidance to principal investigators on computational planning in proposals. Leadership Collaboration and MentorshipPartner with investigators, clinicians, project leads, and other bioinformatics staff to define project goals, analysis strategies, coordinate data workflows, and support scientific goals. Lead multidisciplinary bioinformatics collaborations from project inception through delivery. Mentor junior scientists and analysts in bioinformatics methods, code quality, and scientific interpretation. Foster a culture of scientific rigor, reproducibility, and learning. Contribute reusable, well-documented code to team repositories. Coordinate timelines and deliverables using project management tools (e. g. , Jira, GitHub Projects, Asana) and collaborative workflows. Innovation, Open Science, & Community EngagementContribute to and lead the development of open-source software, reproducible workflows, and institutional tooling. Stay abreast of innovations in bioinformatics tools, databases, and standards. Organize and develop training workshops, tutorials, and best-practice guides to advance team-wide and institutional bioinformatics capacity. Deepen domain-specific expertise (e. g. , pediatric cancer, neurodevelopment, rare disease) through literature synthesis, collaborations with subject matter experts, and community engagement. Represent the organization in consortia, workshops, and national/international scientific forums. Guide institutional practices in reproducibility, open science compliance, and infrastructure sustainability. Use domain knowledge to improve study design and analytical approaches to biological or clinical questions. Organizational AccountabilitiesOrganizational Accountabilities (Leader) Deliver Set and clearly communicate team goals and priorities in alignment with departmental goals and budgets Develop the budget and assign resources to meet the team goals Provide the resources and guidance required for employees to perform effectively Develop procedures to ensure high safety and quality, and course-correct as needed Identify customers' needs and ensure service excellence in meeting those needs Engage Be the link between the department and the team in defining the strategies to meet team goals Provide prompt and clear feedback to staff and support their performance Ensure team adherence to organizational regulations Manage the working environment to promote productivity and motivation Represent the team in clearing obstacles to high performance Hire staff and develop their capabilities Monitor and promote strong employee engagement Grow Encourage and share new ways of making the right work easier to do Recognize and share incremental improvements in operations Promote the success of organizational and department initiatives by clearly aligning programs to the mission Primary Location: District of Columbia-WashingtonWork Locations: Research & Innovation Campus 7144 13th Place NW Washington 20012Job: ResearchOrganization: Ctr Cancer & Immunology RsrchPosition Status: R (Regular) - FT - Full-TimeShift: DayWork Schedule: 40Job Posting: Dec 4, 2025, 2:09:35 PMFull-Time Salary Range: 118393. 6 - 197308. 8

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team This position does not require you to be medical qualified. Demonstrates diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

Fiber Laser Scientist Herndon, VA While working as a Fiber Laser Scientist at Fibertek, you will lead the design and development, integration, and test of advanced fiber laser systems typically with performance requirements beyond the state-of-the-art. Fibertek is a leader in the design, development, and delivery of advanced laser systems and technologies for military and aerospace applications. Your Job We are looking for and experienced and motivated fiber laser scientist or engineer to join a multi-disciplinary team and lead the design and demonstration of advanced laser systems. Example focus missions include space-based laser communications, lidar for tactical defense applications, earth-sensing lidar, and navigational lidars for planetary and docking missions. Fibertek's engineering teams simultaneously tackle laser optical performance beyond state-of-the-art while engineering systems for performance on challenging platforms with limited size, mass, and power and over stressing vibration, thermal, and/or radiation conditions. Delivered systems make a national impact to customers at NASA and throughout the defense community. The work-load will at times include multiple concurrent projects with a mix of short duration research programs and longer duration technology maturation programs resulting in a work culture that is team-oriented, intellectually stimulating, and consistently rewarding. Lead the engineering development of unique laser designs through modeling fiber laser performance, design analysis, component specification, and hardware assembly, integration, and test Coordinate and support the build, alignment, and performance characterization of fiber lasers including multi-stage amplifiers, phase & amplitude modulation implementation, spectral and coherent beam combining Coordinate and perform formal acceptance and qualification testing Participate in customer interactions including formal technical reviews Required Skills and Experience To exceed in this Fiber Laser Scientist role, you'll need the below expertise and experience: MS or PhD in Physics or Optical Engineering w/ a minimum of 5 years of direct hands-on fiber laser experience including designing, building, characterizing laser systems Knowledge of the laser theory and industry best practices associated with fiber laser systems including continuous wave lasers, pulsed, high peak power fiber, advanced fiber architectures, single-frequency injection locked lasers, low frequency noise lasers, electrical and thermal sub-systems. Expertise in laser physics of fiber lasers and amplifiers, including ytterbium, erbium, and/or thulium gain materials. Familiarity with relevant nonlinear processes and impacts to laser performance. Examples include Stimulated Brillouin Scattering, Four-Wave Mixing, Stimulated Raman Scattering, and Transverse Modulational Instability. Foundational understanding of fiber-optic components including types of fibers, pump lasers, couplers, modulators, isolators, mode-field adapters, polarization components, and others. Knowledge of tools for modeling fiber laser performance such as Matlab, RP Power Fiber or equivalent software Ability to design and execute experiments validating laser system performance and correlate the results with the expected performance Strong communication and documentation skills for efficient multidisciplinary communication US citizenship required Please apply today for this full-time Herndon-based Fiber Laser Scientist role and join the leader in the development of state-of-the-art laser and electro-optic solutions. Why Fibertek, Inc? At FIBERTEK, Inc. we pride ourselves in our innovation and customer success focused culture enabled by a creative and relaxed work environment with minimal bureaucracy. Fibertek fosters a progressive learning environment that values inspiration, promotes professional challenge and encourages personal growth. We offer a competitive and incentivized compensation package with excellent benefits. Fibertek, Inc. is an equal opportunity and affirmative action employer. Applicants are considered regardless of race, sex, gender identity, sexual orientation, religion, national origin, disability, protected Veteran status, age or any other protected characteristic in accordance with applicable law. If you need assistance or an accommodation for any part of the application process, please contact us by phone at ************ or via email at ***************.

About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site with some field support Travel: Some (domestic field campaigns, scientific meetings) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $80K - $110K Number of Positions: 5 Job Description: STC is seeking a Support Scientist I to support the ATMOS contract at NASA Goddard Space Flight Center (GSFC). This entry-level scientist role provides research and analysis support to NASA scientists, including model development, data analysis, and operational instrument support. The Support Scientist I will contribute to scientific publications, proposals, and presentations. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Assist with modeling, instrument development, and data analysis. Provide scientific expertise in one or more areas of atmospheric science. Contribute to research proposals, peer-reviewed publications, and conference presentations. Support operations of scientific instruments at GSFC or during field missions. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements Experience in scientific programming (FORTRAN, C/C++, Python). Familiarity with MATLAB, IDL, LabVIEW, or similar analysis tools. Record of academic or research publications desirable. Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or M.S. degree in one of the listed disciplines, plus six years of experience relevant to the position. This experience is in addition to the experience required for the position level.

Data Scientist Systems Integration, Inc. (SII) is a leading provider of customer experience, data analytics and digital transformation solutions . We are seeking a highly skilled Machine Learning Scientist to help the FBI uncover actionable insights from vast and complex data sets. This role focuses on identifying enterprise-level toolsets, applying advanced data mining techniques, and building predictive models that integrate with FBI systems. The ideal candidate will be a strategic thinker with deep technical expertise and the ability to communicate findings clearly across all levels of the organization. Responsibilities: Select, build, and optimize machine learning classifiers using advanced techniques Apply state-of-the-art data mining methods to extract meaningful patterns Enhance data collection procedures to ensure relevance for analytic systems Cleanse, process, and validate data integrity for analysis Conduct ad-hoc analyses and present results in a clear, actionable format Develop and monitor automated anomaly detection systems Design innovative approaches for handling and analyzing large-scale data sets Address fundamental challenges in data handling, search, and retention Solve complex data storage and retrieval issues Develop software solutions to improve data search and access processes Analyze results and deliver recommendations that support mission objectives. Qualifications: Must be US Citizen Requires a Top-Secret clearance (SCI Poly may be required later). Strong understanding of machine learning algorithms (e.g., kNN, Naive Bayes, SVM, Decision Forests) Proficiency with data science toolkits such as R, Weka, NumPy, and MATLAB Excellent communication and presentation skills Experience with tools like Microsoft Power BI, Anaconda, and SPSS Skilled in data visualization using D3.js, GGplot, or similar platforms Proficient in SQL and Hive for querying large datasets Experience with NoSQL databases (e.g., MongoDB, Cassandra, HBase) Solid foundation in applied statistics (distributions, testing, regression) Strong scripting and programming capabilities. Minimum 5 years of experience supporting data-driven projects of similar scope. Bachelor's degree required in data science, statistics, computer science or related field.

Arcellx (************************ is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx's mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible. Primary Objective: The Scientist position is open to highly motivated candidates with a background in oncology, immunology, and translational research who are interested in working within a fast-paced biotechnology company. As a Translational Science Strategist (TSS) based in Gaithersburg, MD, you will join a dynamic Translational Sciences team responsible for developing, implementing, and supporting translational strategy as projects move from discovery to early clinical development. The TSS will be an integral member of cross-functional project teams and will be accountable for developing and driving implementation of translational plans, identifying preclinical models with mechanistic alignment to human disease, defining the preclinical and early clinical biomarker strategy, and helping to build the early clinical development plan. Main Accountabilities: Contribute relevant scientific expertise, strategy, and experimentally-derived insights as a member of multidisciplinary project teams working to drive the preclinical to clinical translation of pipeline assets Plan, design, and execute IND-enabling pharmacology, pharmacokinetic and toxicology studies by applying knowledge of disease-associated pathways, preclinical models, and drug development Contribute to the preparation of IND applications and other regulatory documents, as appropriate Collaborate cross-functionally to enable translation of preclinical hypotheses into clinical biomarker strategies and to guide patient stratification Design and conduct studies to inform disease area strategy for target selection and validation Establish and cultivate relationships with external CRO collaborators for basic and translational research Analyze and interpret experimental data readouts and present results at internal meetings and scientific conferences Maintain an awareness of new/emerging techniques, tools and clinical findings relevant to the field Preferred Qualifications: PhD, MD or MD/PhD degree in a relevant scientific field ( e.g. , cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years experience in drug discovery or drug development Demonstrated record of research accomplishment as evidenced by publications or major contributions to drug development milestones Experience with large, multimodal data sets and familiarity with techniques for exploring associations of biomarkers with clinical outcomes Strategic thinker with proven leadership skills and/or prior project team leadership roles Proficiency in distilling complex issues and clearly articulating viable paths forward Competencies: Commitment to ethical scientific investigations and rigorous experimental methods Ability and desire to multitask and function in a fast-paced entrepreneurial environment Sense of urgency in performance of duties Interpersonal skills that promote a collaborative and productive team environment Outstanding presentation and communication skills

US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description • BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations. • This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data. • The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment. Qualifications Education: • Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field. Experience: • For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience. • For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience. Additional Information Special Skills/ Abilities • Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred. • Good documentation, writing and communication skills in a team based setting are essential.

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical