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  • Sr. Applied Scientist, Amazon Ads

    Amazon 4.7company rating

    Principal research scientist job in Santa Monica, CA

    Application deadline: Applications will be accepted on an ongoing basis Amazon Ads is re-imagining advertising through cutting-edge generative artificial intelligence (AI) technologies. We combine human creativity with AI to transform every aspect of the advertising life cycle-from ad creation and optimization to performance analysis and customer insights. Our solutions help advertisers grow their brands while enabling millions of customers to discover and purchase products through delightful experiences. We deliver billions of ad impressions and millions of clicks daily, breaking fresh ground in product and technical innovations. If you're energized by solving complex challenges and pushing the boundaries of what's possible with AI, join us in shaping the future of advertising. Why you'll love this role: This role offers unprecedented breadth in ML applications and access to extensive computational resources and rich datasets that will enable you to build truly innovative solutions. You'll work on projects that span the full advertising life cycle, from sophisticated ranking algorithms and real-time bidding systems to creative optimization and measurement solutions. You'll work alongside talented engineers, scientists, and product leaders in a culture that encourages innovation, experimentation, and bias for action, and you'll directly influence business strategy through your scientific expertise. What makes this role unique is the combination of scientific rigor with real-world impact. You'll re-imagine advertising through the lens of advanced ML while solving problems that balance the needs of advertisers, customers, and Amazon's business objectives. Your impact and career growth: Amazon Ads is investing heavily in AI and ML capabilities, creating opportunities for scientists to innovate and make their marks. Your work will directly impact millions. Whether you see yourself growing as an individual contributor or moving into people management, there are clear paths for career progression. This role combines scientific leadership, organizational ability, technical strength, and business understanding. You'll have opportunities to lead technical initiatives, mentor other scientists, and collaborate with senior leadership to shape the future of advertising technology. Most importantly, you'll be part of a community that values scientific excellence and encourages you to push the boundaries of what's possible with AI. Watch two Applied Scientists at Amazon Ads talk about their work: ********************************** HsURsIPEA Learn more about Amazon Ads: ******************************* Key job responsibilities As a Senior Applied Scientist in Amazon Ads, you will: - Research and implement cutting-edge ML approaches, including applications of generative AI and large language models - Develop and deploy innovative ML solutions spanning multiple disciplines - from ranking and personalization to natural language processing, computer vision, recommender systems, and large language models - Drive end-to-end projects that tackle ambiguous problems at massive scale, often working with petabytes of data - Build and optimize models that balance multiple stakeholder needs - helping customers discover relevant products while enabling advertisers to achieve their goals efficiently - Build ML models, perform proof-of-concept, experiment, optimize, and deploy your models into production, working closely with cross-functional teams including engineers, product managers, and other scientists - Design and run A/B experiments to validate hypotheses, gather insights from large-scale data analysis, and measure business impact - Develop scalable, efficient processes for model development, validation, and deployment that optimize traffic monetization while maintaining customer experience Basic Qualifications - 5+ years of building machine learning models for business application experience - PhD, or Master's degree and 6+ years of applied research experience - Experience programming in Java, C++, Python or related language - Experience with neural deep learning methods and machine learning Preferred Qualifications - Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc. - Experience with large scale distributed systems such as Hadoop, Spark etc. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The Colorado base pay for this position ranges from $167,100/year up to $226,100/year. The National base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************* . This position will remain posted until filled. Applicants should apply via our internal or external career site.
    $150.4k-260k yearly 5d ago
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  • Associate Principal Data Scientist

    Activision Blizzard, Inc. 4.6company rating

    Principal research scientist job in Santa Monica, CA

    Job Title:Associate Principal Data ScientistRequisition ID:R025545Job Description:Your Role Within Our KingdomWe are seeking an Associate Principal Data Scientist-a highly experienced and technically deep individual contributor who leads through influence, owns high-impact initiatives, and drives scientific excellence across experimentation and modeling.Responsibilities: Lead the design and execution of large-scale data science initiatives, shaping the roadmap for experimentation and modeling across teams. Apply advanced statistical, optimization, and machine learning techniques (e.g., time-series, regression/classification, recommendation engines, reinforcement learning, and gen AI) to drive system understanding and develop data-powered solutions across the organization. Own design and evaluation of experimentation for optimization systems. Provide technical direction, mentor senior data scientists, and set high standards for scientific rigor, communication, and reproducibility. Partner cross-functionally with Product, Engineering, and Game Studios to frame ambiguous problems, scope solutions, and influence strategy. Champion innovation by evaluating new methodologies and tools, and by raising the bar for scalable, interpretable, and actionable data science. Skills to Create ThrillsMinimum Qualifications: Master's degree or PhD in a quantitative field (e.g., Statistics, Mathematics, Computer Science, Economics, Engineering, Operations Research). 14+ years of industry experience (or equivalent post-graduate experience) in data science, experimentation, statistical modeling, and machine learning, including work with large-scale systems. Proficient in Python and SQL; familiarity with big data tools (e.g., Spark, Hive) and cloud computing platforms (e.g., GCP, AWS). Strong systems thinking-able to zoom out and define strategy while also diving deep into code and analysis. Excellent communication and collaboration skills, with demonstrated experience partnering across Product, Engineering and Businessteams. Demonstrated experience mentoring, influencing, and elevating the technical bar across a data science organization. Bonus Points Experience working with advertising data products or monetization systems. Prior work with mobile gaming studios or player behavior modeling. Experience in developing or maintaining experimentation platforms. Familiarity with modern data orchestration and versioning (e.g., Airflow, dbt, MLflow). We love hearing from anyone who is enthusiastic about changing the games industry. Not sure you meet all qualifications? Let us decide! Research shows that women, veterans, and members of other under-represented groups tend to not apply to jobs when they think they may not meet every qualification, when, in fact, they often do! We are committed to creating a diverse and inclusive environment and strongly encourage you to apply.We are committed to working with and providing reasonable assistance to individuals with physical and mental disabilities. If you are a disabled individual requiring an accommodation to apply for an open position, please email your request to accommodationrequests@activisionblizzard.com. General employment questions cannot be accepted or processed here. Thank you for your interest.We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, gender identity, age, marital status, veteran status, or disability status, among other characteristics. Rewards We provide a suite of benefits that promote physical, emotional and financial well-being for ‘Every World' - we've got our employees covered! Subject to eligibility requirements, the Company offers comprehensive benefits including: Medical, dental, vision, health savings account or health reimbursement account, healthcare spending accounts, dependent care spending accounts, life and AD&D insurance, disability insurance; 401(k) with Company match, tuition reimbursement, charitable donation matching; Paid holidays and vacation, paid sick time, floating holidays, compassion and bereavement leaves, parental leave; Mental health & wellbeing programs, fitness programs, free and discounted games, and a variety of other voluntary benefit programs like supplemental life & disability, legal service, ID protection, rental insurance, and others; If the Company requires that you move geographic locations for the job, then you may also be eligible for relocation assistance. Eligibility to participate in these benefits may vary for part time and temporary full-time employees and interns with the Company. You can learn more by visiting *************************************** In the U.S., the standard base pay range for this role is $143,060.00 - $264,846.00 Annual. These values reflect the expected base pay range of new hires across all U.S. locations. Ultimately, your specific range and offer will be based on several factors, including relevant experience, performance, and work location. Your Talent Professional can share this role's range details for your local geography during the hiring process. In addition to a competitive base pay, employees in this role may be eligible for incentive compensation. Incentive compensation is not guaranteed. While we strive to provide competitive offers to successful candidates, new hire compensation is negotiable. #J-18808-Ljbffr
    $143.1k-264.8k yearly 5d ago
  • Lead Target Discovery Scientist - In Vitro Biology

    Amgen Sa 4.8company rating

    Principal research scientist job in Thousand Oaks, CA

    A leading biotech company in Thousand Oaks seeks a Senior Principal Scientist to lead a team focused on in vitro modeling for target discovery. This role involves collaboration across therapeutic areas and implementing innovative technologies. Candidates should have a doctorate and extensive experience in a related field. Competitive compensation, flexible work models, and a comprehensive benefits package are offered. #J-18808-Ljbffr
    $125k-173k yearly est. 2d ago
  • Senior Applied AI Scientist

    Cisco 4.8company rating

    Principal research scientist job in Santa Monica, CA

    **Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. **Your Impact** + Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. + Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. + Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. + Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. + Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. **Minimum Qualifications:** + PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. + Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. + Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) + Experience translating research ideas into production systems. **Preferred Qualifications:** + Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. + Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. + Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. + Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. + Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. + MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. + Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. **Why Cisco?** At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. **Message to applicants applying to work in the U.S. and/or Canada:** The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: + 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees + 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco + Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees + Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) + 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next + Additional paid time away may be requested to deal with critical or emergency issues for family members + Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: + .75% of incentive target for each 1% of revenue attainment up to 50% of quota; + 1.5% of incentive target for each 1% of attainment between 50% and 75%; + 1% of incentive target for each 1% of attainment between 75% and 100%; and + Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. ** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements. Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis. Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.
    $199.7k-292.8k yearly 60d+ ago
  • Associate Director/Principal Scientist, CMC Analytical Chemistry

    Latigo Bio

    Principal research scientist job in Thousand Oaks, CA

    Job: Associate Director/Principal Scientist, CMC Analytical Chemistry Position type: Full Time Reports to: Director of Analytical Chemistry Organization Overview Latigo Biotherapeutics (LatigoBio) is a private, early-stage biotechnology company discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes to transform the lives of patients. Latigo has a robust pipeline, is well-funded by blue chip investors, and has a highly successful management team and Board of Directors. The company was founded in 2019 and is based in Thousand Oaks, CA. We are science-based, data-driven, patient-focused, and forward-thinking. Position Summary Latigo is searching for an Associate Director/Principal Scientist, CMC Analytical Chemistry. Reporting to the Director of Analytical Chemistry, the candidate will manage preclinical to clinical analytical development activities and oversee the testing and release of drug substance and drug product at contract manufacturers/service providers. The role is responsible for the development, validation and implementation of QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials at contract manufacturers. Additional responsibilities include reference standard qualification and management, establishment of specifications, oversight of stability programs and the active management and documentation of data. The selected candidate will also work collaboratively with Quality Assurance to assess laboratory conformance with cGMPs, and with CMC Regulatory Affairs to author Module 3 sections of CTD regulatory submissions and written responses to regulatory authorities. Primary Responsibilities Oversee the phase-appropriate analytical activity at contract manufacturers/service providers including analytical method development, qualification and validation for drug substance and drug product. Partner with stakeholders to develop and set specifications for raw materials, intermediates, drug substance, excipients and drug product. Design and manage stability programs for non-GMP and cGMP drug substance and drug product batches and provide guidance for shelf-life and expiry dating. Establish workflows and procedures for analytical and quality control activities. Manage reference standards program, coordinate sourcing, ensure inventory, plan and execute testing and retesting activities, and manage shipments of reference standards. Author, review and approve various analytical reports in a timely manner to support drug substance and drug product development and manufacture, and regulatory filings. Support regulatory submissions by drafting and reviewing analytical sections of INDs, IMPDs, and NDAs, and ensure compliance with current regulatory requirements. Sometimes represent analytical function in CMC teams and project meetings, and work closely with cross-functional teams to meet project timelines and goals. Review/approve controlled cGMP documents, e.g., analytical methods and associated validation protocols/reports, specifications, stability protocols, change controls, LIRs, etc. Manage/perform QC review/approval of analytical test data for IPC testing, drug substance/product batch release and stability test data. Manage and review deviation events and OOS/OOT investigations in coordination with CMC counterparts, QA and regulatory team members. Contribute to the building of CMC infrastructure and company culture. Qualifications and Requirements D. with 8+ years of experience or BS or MS in chemistry or related discipline with 10-15 years of industry experience in an analytical chemistry setting. Good understanding and knowledge of pharmaceutical analytical methods and related issues. Experience with analytical development of small molecules and drug product oral dosage forms from preclinical to late-stage clinical development. Experience managing drug substance and drug product service providers in analytical matters. Extensive knowledge of GLP and cGMP requirements, appropriate regulatory guidance and current industry practices for analytical development. Experience in writing CMC sections for Regulatory submissions (IND experience required; NDA experience highly desirable). Excellent computer skills (e.g., Microsoft Office, Excel, Project). Ability to effectively manage multiple priorities and projects. Preference given to applicants able to work (hybrid) from Thousand Oaks or San Francisco, CA offices.
    $117k-184k yearly est. 6d ago
  • Research Scientist, Hearing Performance

    Sonova

    Principal research scientist job in Santa Clarita, CA

    Valencia, CA - Hybrid Research Scientist, Hearing Performance You will deliver better outcomes for cochlear implant recipients by driving feasibility research in hearing performance and remote care. You will design and conduct early-stage research studies to evaluate novel concepts. You will collaborate closely with internal R&D engineers, and with external clinics and academic researchers for study execution. In addition, you will aid in the development of research software. You will thrive in an interdisciplinary environment of researchers, clinicians, and technologists who are passionate about connecting patients to sound. Responsibilities: * Design and conduct feasibility studies to further improve hearing performance of cochlear implant recipients, including signal processing strategies and remote care solutions. * Collaborate with multi-functional internal teams (software development, clinical research, marketing, quality, etc.). * Manage collaborations with external partners (clinicians, academic researchers) to conduct research studies and validate concepts. * Aiding in the development of research software using Python and MATLAB. * Communicate findings through technical documentation, presentations to internal and external stakeholders, and, where appropriate, manuscripts for publication. * Support development of intellectual property. Travelling Requirement: 5% for visits to clinics, conferences, and external collaborators. More about you: * Degree in Hearing Science, Audiology, or related field; PhD preferred. * Research background in cochlear implants, hearing aids, or related areas, plus 3+ years of industry experience in audio or medical devices. * Strong project ownership, ability to navigate ambiguity, and excellent organizational skills. * Effective communicator with a collaborative mindset and ability to work with diverse teams. * Proven leadership in driving projects and external research collaborations, including developing and presenting impactful concepts. * Broad expertise in hearing performance, signal processing, statistics, machine learning, and research software development. * Proficient in Python, MATLAB, Microsoft Office, SQL, R, and Rust; fluent in English A minimum of 200Mb/sec download and 10Mb/sec upload speed internet connectivity is required to support any remote/hybrid employee functionality at Sonova Don't meet all the criteria? If you're willing to go all in and learn we'd love to hear from you! We are looking forward to receiving your application via our online job application platform. For this position only direct applications will be considered. Sonova does not recruit via app, telegram, carrier pigeon or any other format that does not include speaking with an actual human. If you are offered a job without speaking with someone please contact Sonova Human Resources What we offer: * Medical, dental and vision coverage* * Health Savings, Health Reimbursement, Flexible Spending/Dependent Care Accounts * TeleHealth options * 401k plan with company match* * Company paid life/ad&d insurance * Additional supplemental life/ad&d coverage available * Company paid Short/Long-Term Disability coverage (STD/LTD) * STD LTD Buy-ups available * Accident/Hospital Indemnity coverage * Legal/ID Theft Assistance * PTO (or sick and vacation time), floating Diversity Day, & paid holidays* * Paid parental bonding leave * Employee Assistance Program (24/7 mental health support hotline, 5 company paid counseling sessions and more) * Robust Internal Career Growth opportunities * Tuition reimbursement * Hearing aid discount for employees and family * Internal social recognition platform * Plan rules/offerings dependent upon group Company/location. This role's pay range is between $95,200/yr - $142,800/yr. This role is also bonus eligible. How we work: At Sonova, we prioritize the well-being of our employees and foster an inclusive environment that promotes engagement and collaboration. Our team-customized hybrid work model empowers teams to balance individual needs with business goals, offering flexibility and individualized time management. We recognize the importance of life outside of work and strive to create a supportive and motivating workplace where innovation thrives. Sonova is an equal opportunity employer We team up. We grow talent. We collaborate with people of diverse backgrounds to win with the best team in the market place. We guarantee every person equal treatment in regard to employment and opportunity for employment, regardless of a candidate's ethnic or national origin, religion, sexual orientation or marital status, gender, genetic identity, age, disability or any other legally protected status.
    $95.2k-142.8k yearly 20d ago
  • Clinical Research Physician Investigator

    Sansum Diabetes Research Institute 3.9company rating

    Principal research scientist job in Santa Barbara, CA

    Sansum Diabetes Research Institute has an opportunity for a full-time, board certified, or board-eligible Endocrinologist to serve as a Clinical Research Physician Investigator. SDRI is a non-profit organization and center of excellence with a mission to improve the lives of people impacted by diabetes through research, education, and clinical care. We are a preferred site for industry sponsored clinical trials, a testament to our exceptional research capabilities. On average, SDRI conducts 25+ trials per year, engaging approximately 1,000 participants. Current industry partners include Abbott, Dexcom, Insulet, Eli Lilly, Mannkind, Medtronic Diabetes, Novo Nordisk, Sanofi, Tandem Diabetes Care, and more. We are experts with experience across all study phases, and a broad portfolio of trials and clinical work focused on diabetes and metabolic health. Diversity and inclusivity are prioritized in in our clinical trials---in 2023, 30% of our research participants were from underrepresented populations. We are currently renovating our 18,000 square foot research facility to create a state-of-the-art center where we will accelerate life-changing diabetes research. Position Details: Responsible for 12+ Industry Sponsored Trials Per Year Design, Fund, and Execute Investigator Initiated Trials Develop Strategies and Partnerships to Drive Innovation Across the Enterprise Opportunity to Maintain a Clinical Practice through our Clinics Standard Office Hours Salaried Position: $250,000 - $350,000 Annually NOTE: The listed range is solely a base compensation for experienced full-time physician researchers. It does not include incentives and benefits. The base compensation rate may be adjusted based on training, community need and other possible determining factors. We Offer: Medical/Dental/Vision CME Stipend Malpractice Insurance Disability Retirement 403 (b) Annual Leave and Sick Time Licensure/DEA/Board Exam Fees PSLF Eligibility Requirements: MD or DO with Directly Related Experience in Endocrinology Board Certified or Board Eligible in Endocrinology DEA Certificate Eligible to Work in the United States, Must be in or Relocate to Santa Barbara, CA CA Licensure or the Ability to Obtain CA Licensure Interest in Research, Experience with Research preferred Exceptional Communication and Interpersonal Skills About Santa Barbara: Santa Barbara is known as The American Riviera thanks to its Spanish Colonial Revival architecture, rich heritage, world-renowned food and wine scene, stunning natural beauty and near-perfect weather. We invite you to learn more and to consider joining us at SDRI where you will join an experienced cross-functional team focused on developing and executing trials targeting innovation and excellence crossing drugs, devices, and technology that will impact the health span and life span of people living with diabetes.
    $90k-134k yearly est. 24d ago
  • Data analysis-Associate Scientist

    Mindlance 4.6company rating

    Principal research scientist job in Thousand Oaks, CA

    Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at ************************* Job Description Job Summary: Responsible for providing support to the Process Analytics group, a unit within the Digital Integration & Predictive Technologies (DIPT) organization in Process Development. The position will be based in Thousand Oaks, CA. Support will include organizing and interpreting lab data, analyzing results using statistical techniques. The responsibilities also include performing laboratory experiments including unit operations set up, calibration of various lab tools, sampling and data acquisition from primary or secondary data sources with minimal supervision. Basic Qualifications • Bachelor's degree OR • Associate's degree & 4 years of directly related experience OR • High school diploma / GED & 6 years of directly related experience Preferred Qualifications • B.Sc., in Chemical, Biochemical Engineering or Life Sciences, preferably with expertise in bio/pharmaceutical processes. • Practical experience and interest in multivariate data analysis and predictive modeling. • Experience working with large data sets, data mining and machine learning tools. • Experience in Matlab or R Programming Languages and basic Microsoft tools. • Understanding of biopharmaceuticals process, related unit operations including analytical methods and process controls. • Strong analytical skills with the ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy • Independent, self-motivated, organized, able to multi-task in project environments, and skilled in communication, facilitation, and collaboration. • Team player, prepared to work in and embrace a team-based culture that relies on collaboration for effective decision-making • Solid leadership, technical writing, and communication/presentation skills. Qualifications Basic Qualifications • Bachelor's degree OR • Associate's degree & 4 years of directly related experience OR • High school diploma / GED & 6 years of directly related experience Preferred Qualifications • B.Sc., in Chemical, Biochemical Engineering or Life Sciences, preferably with expertise in bio/pharmaceutical processes. • Practical experience and interest in multivariate data analysis and predictive modeling. • Experience working with large data sets, data mining and machine learning tools. • Experience in Matlab or R Programming Languages and basic Microsoft tools. • Understanding of biopharmaceuticals process, related unit operations including analytical methods and process controls. • Strong analytical skills with the ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy • Independent, self-motivated, organized, able to multi-task in project environments, and skilled in communication, facilitation, and collaboration. • Team player, prepared to work in and embrace a team-based culture that relies on collaboration for effective decision-making • Solid leadership, technical writing, and communication/presentation skills. Additional Information All your information will be kept confidential according to EEO guidelines.
    $84k-121k yearly est. 60d+ ago
  • Scientist

    The Steely Group

    Principal research scientist job in Thousand Oaks, CA

    The Scientist will support microbiology related methods such as, endotoxin, bioburden, sterility and other compendial methods associated with microbial control. Hands on laboratory work include method troubleshooting, and involvement in evaluating new technologies related to rapid microbiology methods, including developing and executing feasibility and/or validation studies. The candidate will require to work in the laboratory to support feasibility and/or validation studies (time spent in lab varies depending on projects). Experience in pharmaceutical/biotechnology microbiology and manufacturing are preferred. The candidate would be a part of a team that supports various microbiology methods in various stages of the product life cycle. This team supports programs/methods at locations throughout the company. The Scientist collaborates with representatives from key functions within Process Development, Manufacturing, and Quality. Basic Qualifications: Doctorate Degree OR Master's Degree and 4 years of Scientific Experience OR Bachelor's degree and 6 years of Scientific experience Preferred Qualifications: Prior experience in Microbiological Quality at the technical level, including experience with sterile filtration validations Advanced understanding and hands-on experience in various analytical platform such as compendial microbial methods, rapid methods for microbial detection/identification and advanced technologies for detection of bacteria Excellent written and oral communication skills for the timely documentation, presentation and discussion of scientific results in a fast-paced, multi-disciplinary, team-based environment. Advanced ability to critically analyze and interrogate various analytical data sets (e.g. complex dilution schemes) to drive and influence the investigational process Advanced root cause analysis capabilities including leading advanced and complex events Advanced ability to propose and lead new scientific imperatives/initiatives Expert in an investigational laboratory setting within a pharmaceutical or biotechnology company Advanced experience in working closely with scientific and manufacturing disciplines across process development, clinical, and commercial operations Familiarity with cGMP regulations, FDA and EU regulations and guidelines
    $99k-157k yearly est. 2d ago
  • Postdoctoral Scientist - Smidt Heart Institute (Chugh Lab)

    Dev 4.2company rating

    Principal research scientist job in Malibu, CA

    Company DescriptionJobs for Humanity is partnering with CEDARS-SINAI to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located. Company Name: CEDARS-SINAI Job Description Grow your career at Cedars-Sinai! The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and niche care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. Join our team and use your experience with an organization known nationally for excellence in research! JOB SUMMARY: Working independently but in close cooperation and in consultation with the Director, Center for Cardiac Arrest Prevention (CCAP), the Research Fellow will be involved in new and ongoing projects at the CCAP. Funded by grants from NIH/NHLBI, the mission of the CCAP is to discover and implement novel clinical tools for prediction and prevention of sudden cardiac arrest, thereby reducing the burden of sudden cardiac death in the community CCAP. Unique opportunities to analyze existing data and publish papers. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: - May assist in preparation of grant proposals but is not responsible for generating grant funds. - May participate in publications and presentations as author or co-author. - Designs and performs analyses independently or semi-independently. Will keep appropriate experimental records and documentation and discuss the results with the Principal Investigator. - May develop, adapt, and implement new research techniques and protocols. - Analyzes, interprets, summarizes and compiles data. - Performs routine and complex analyses throughout training period. - May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Educational Requirements: Doctorate (MD) plus clinical cardiology/clinical electrophysiology sub-specialty clinical training for at least two years. Experience: - 1 year experience acquired thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment - Should have written and published scientific papers. - Has demonstrated aptitude to ask research questions and successfully published papers and/or had grants funded. Physical Demands: - Able to perform moderate lifting. - Able to sit, stand and walk for prolonged periods of time. - Able to read papers and online documents. - Able to operate standard office equipment. - Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions. Working Title: Postdoctoral Scientist - Smidt Heart Institute (Chugh Lab) Department: Heart Institute Operations Business Entity: Cedars-Sinai Medical Center Job Category: Academic/Research Job Specialty: Postdoctoral Position Type: Full-time Shift Length: 8 hour shift Shift Type: Day Base Pay:$64,500.00 - $93,600.00
    $64.5k-93.6k yearly 60d+ ago
  • Associate Scientist

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Thousand Oaks, CA

    100% Onsite Must be local in ATO **Job Details:** + Candidate will be essential on site. 1+ year of industry or 2+ academia experience in a lab setting with pipetting, sample prep & handling, HPLC chromatography, and protein sample analysis. Ideal Candidate: must have at least 1-year lab experience. BS (or equivalent) degree in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline. + A strong understanding of protein biochemistry and protein structure, as well as significant experience with basic laboratory skills and biophysical techniques related to protein analysis is essential. A background in protein solution manipulation (e.g. pipetting, dialysis, concentration) and HPLC analysis is expected. Experience with visible and sub-visible particle analysis and other analytical methods (e.g. capillary electrophoresis, SEC, CEX, etc.) is desirable. **Job description** : + We are currently seeking a research associate for the Drug Product Technologies group in Thousand Oaks, CA. + A fundamental understanding of protein chemistry, formulation, and biophysical characterization is desired. The successful candidate will perform experiments related to the development of formulations for therapeutic proteins, including stability testing and analytical characterization. + The candidate will join a team of investigators using a variety of biochemical and biophysical techniques and will be involved in the design and execution of experiments. + Responsibilities will include detailed record keeping in electronic laboratory notebooks, data collection, analysis, and interpretation of experimental data and presentation. **Basic qualifications:** + BS (or equivalent) degree in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline. A strong understanding of protein biochemistry and protein structure, as well as significant experience with basic laboratory skills and biophysical techniques related to protein analysis is essential. + The applicants must be motivated, have good problem-solving skills, and an aptitude to learn and implement new techniques/skills. + The candidate should be well organized and proficient in detailed record-keeping, have excellent written and oral communication skills, must be proficient in Microsoft office (word, excel, PowerPoint), and be capable of working efficiently in teams and independently. **Advanced qualifications:** + MS (or equivalent) in pharmaceutics, biochemistry, chemistry, biology or related life sciences discipline. MS (or equivalent) is not required but it is preferred. **Basic Qualifications:** + Masters degree OR + Bachelors degree and 2 years of experience OR + Associate's degree and 4 years of experience OR + High school diploma / GED and 6 years of experience **Top 3 Must Have Skill Sets:** + Lab experiences, 100% onsite, looking for permanent job in industry **Day to Day Responsibilities:** + Using a variety of biochemical and biophysical techniques and will be involved in the design and execution of experiments. Responsibilities will include detailed record keeping in electronic laboratory notebooks, data collection, analysis, and interpretation of experimental data and presentation. **About US Tech Solutions:** _US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit_ _************************ _._ _"US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran"_
    $67k-101k yearly est. 8d ago
  • Associate Scientist Analytical Chemistry

    Provivi 3.9company rating

    Principal research scientist job in Santa Monica, CA

    ProviviOverview We are amulti-national,Santa Monica-based company, founded in 2013 by Caltech scholars: Professor Frances Arnold, PedroCoelho,and Peter Meinhold.Wererethinking pest controlas innovators in pheromone technology, theengineersand creators of a family ofsafe andeffective pest control solutions formajor damaging insects. We are hiring thevery bestand brightest people toexpand our impact. Role Description As a member of the Provivistechnologyteam, you willhave a vital role in developingandvalidatinganalyticalmethods for detection, identification,and quantification ofsmallmolecules found in Provivisproprietarychemical andbiochemicalprocesses as well as pheromone components informulated products.Specifically, the successful candidate will develop andvalidate GC,GCMS,HPLC,and HPIC methods,as well asestablishquality controlprotocolsfor Proviviscommercial products,provide hands-on technicalassistancetomaintainanalytical equipmentin good working orders, and analyze samples supporting various projects.Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems,are essential. ResponsibilitiesInclude Develops,validates, and standardizes GC, HPLC, HPICanalytical methods for detection, identification,and quantification ofsmallmoleculesfound inchemical andbiochemicalprocesses, andformulated products. Extracts,analyzesandevaluatesmaterial and products at all stages of development process under stringent quality and time requirements. Preparesresearch reports, invention disclosures, and Standard Operating Procedures for internal and external use. Reviewsdata for technical content and regulatory compliance. Ensuresanalytical equipmentismaintainedin good working order; troubleshootsand performsminor repairs as needed. Anticipatesadditionalresources,consumables, andequipment requirementsas needed to ensure that workcan be completed within the budgeted time. Remains current withanalyticalchemistry literature and champions the implementation ofnewtechnology. Maintainsa safe and orderly laboratory andensurescompliance with all safety policies and practices. Qualifications& Skills Include M.S. inanalyticalchemistry or equivalent, orbachelor'sin chemistrywith 2additionalyears of analytical lab experience A minimum of0-2years ofbiotech and chemicalindustrial experience with hands-on experience in analytical chemistry. A good understanding of analytical chemistry, organicchemistry,and chemical engineering principles. Demonstrated practical ability to develop methods forisolation,characterization, and quantification ofsmallmoleculesfound inchemical and biochemicalprocesses and formulatedproducts usingconventional chromatography techniques and analytical instruments including GC,GCMS,HPLC,and NMR. Must be skilled in operation of chromatographic data acquisition and processing software packages such as Chromeleon,ChemStation,and other software tools for data reduction and presentation. Excellent written, reporting, and verbal communication skills Proficient in using Microsoft Officesuiteincluding Word, Excel,and Power Point. Ability to prioritize responsibilities and multi-taskin a fast-paced environment with changing priorities Must behighly motivatedand capable of working independently to deliver results under tight deadlines Able to lift 15 40 pounds. Diversity and Equal Opportunity Employment Proviviis an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protectedveteransstatus, or any otherlegally-protectedfactors.
    $76k-115k yearly est. 6d ago
  • Associate Scientist - Bioinformatics

    Lancesoft 4.5company rating

    Principal research scientist job in Santa Monica, CA

    We are seeking a talented and highly motivated scientist with an interest in advancing Next Generation Sequencing (NGS) technologies for genomics research, to join our Bioinformatics and Sequencing group in Santa Monica. You will have the opportunity to work in a fast-paced and highly collaborative environment to support a growing R&D portfolio. You will work at the interface of biology and technology and will support the effort on assessment and development of custom NGS needs, to assist drug target and biomarker discovery efforts. Responsibilities Extraction and preparation of DNA and RNA from various sources Preparation of DNA, RNA, and ATAC-seq libraries from bulk and/or single cells for NGS sequencing Perform quality control on samples and libraries. Troubleshoot the experimental procedures and protocols for library preparation and sequencing under supervision Perform Next Generation Sequencing experiments on Illumina platforms and other platforms Perform qPCR for library quality control Maintain updated working knowledge of Genomics technologies and develop significant experience in next-generation sequencing applications Keep records of experiments in electronic notebook (ELN) Deliver scientific findings effectively in group meetings and collaborative forums Basic Qualifications Master s Degree OR Bachelor s Degree and 2+ years of scientific experience OR AA Degree and 4+ years of scientific experience OR High School Degree and 5+ years of scientific experience Preferred Qualifications Bachelor's degree in Biological Sciences, Molecular Biology, Biochemistry, Bioengineering, Genetics, or related fields 2+ years of hands-on experience with Next Generation Sequencing (NGS) platforms, various NGS assays, and their underlying sequencing methodology Hands-on experience with DNA and RNA extraction from various sources Ability to learn new techniques in a fast-paced environment Demonstrated ability to solve scientific and engineering problems Excellent organizational skills and efficiency at getting tasks done Goal oriented and looking to take on additional responsibilities Experience working in a multi-disciplinary environment Experience working with LIMS and electronic notebook e.G. Benchling Excellent interpersonal, verbal, and written communication skills An excellent work ethic, ability to work in a dynamic environment, and ability to adapt to changing priorities
    $85k-133k yearly est. 15d ago
  • Associate Scientist

    Actalent

    Principal research scientist job in Thousand Oaks, CA

    We are currently seeking a dedicated Associate Scientist to join the Drug Product Technologies group in Thousand Oaks, CA. This role requires a strong understanding of protein chemistry, formulation, and biophysical characterization. The successful candidate will be responsible for performing experiments related to the development of formulations for therapeutic proteins, including stability testing and analytical characterization. Responsibilities * Perform experiments related to the development of formulations for therapeutic proteins. * Conduct stability testing and analytical characterization. * Design and execute experiments using a variety of biochemical and biophysical techniques. * Maintain detailed records in electronic laboratory notebooks. * Collect, analyze, and interpret experimental data. * Present findings and data clearly. * Collaborate effectively with team members and work independently as needed. Essential Skills * 1 year of industry experience or 2 years in academia in a lab setting. * BS or equivalent degree in pharmaceutics, biochemistry, chemistry, biology, or a related life sciences discipline. * Strong understanding of protein biochemistry and protein structure. * Experience with basic laboratory skills and biophysical techniques related to protein analysis. * Proficiency in pipetting, dialysis, concentration, and HPLC analysis. Additional Skills & Qualifications * Experience with visible and sub-visible particle analysis. * Familiarity with analytical methods such as capillary electrophoresis, SEC, and CEX. * MS or equivalent in pharmaceutics, biochemistry, chemistry, biology, or related life sciences discipline (preferred, not required). * Proficient in Microsoft Office Suite including Word, Excel, and PowerPoint. * Excellent written and oral communication skills. * Strong problem-solving skills and aptitude to learn new techniques. Work Environment The position is 100% onsite and requires the candidate to be local to the area. The work schedule is Monday through Friday from 9:00 am to 5:00 pm PST. The work involves collaboration with a team of investigators and requires proficiency in maintaining detailed records and data presentation. Job Type & Location This is a Contract position based out of Thousand Oaks, CA. Pay and Benefits The pay range for this position is $26.00 - $30.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Thousand Oaks,CA. Application Deadline This position is anticipated to close on Feb 4, 2026. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
    $26-30 hourly 7d ago
  • Senior Applied AI Scientist

    Cisco Systems, Inc. 4.8company rating

    Principal research scientist job in Santa Monica, CA

    Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.
    $199.7k-292.8k yearly 60d+ ago
  • Associate Director/Principal Scientist, CMC Analytical Chemistry

    Latigo Bio

    Principal research scientist job in Thousand Oaks, CA

    Job: Associate Director/Principal Scientist, CMC Analytical Chemistry Position type: Full Time Reports to: Director of Analytical Chemistry Latigo Biotherapeutics (LatigoBio) is a private, early-stage biotechnology company discovering and developing the next generation of non-opioid medicines for pain and pain-related syndromes to transform the lives of patients. Latigo has a robust pipeline, is well-funded by blue chip investors, and has a highly successful management team and Board of Directors. The company was founded in 2019 and is based in Thousand Oaks, CA. We are science-based, data-driven, patient-focused, and forward-thinking. Position Summary Latigo is searching for an Associate Director/Principal Scientist, CMC Analytical Chemistry. Reporting to the Director of Analytical Chemistry, the candidate will manage preclinical to clinical analytical development activities and oversee the testing and release of drug substance and drug product at contract manufacturers/service providers. The role is responsible for the development, validation and implementation of QC methods for drug substance, drug product, intermediates, starting materials, excipients, and packaging materials at contract manufacturers. Additional responsibilities include reference standard qualification and management, establishment of specifications, oversight of stability programs and the active management and documentation of data. The selected candidate will also work collaboratively with Quality Assurance to assess laboratory conformance with cGMPs, and with CMC Regulatory Affairs to author Module 3 sections of CTD regulatory submissions and written responses to regulatory authorities. Primary Responsibilities Oversee the phase-appropriate analytical activity at contract manufacturers/service providers including analytical method development, qualification and validation for drug substance and drug product. Partner with stakeholders to develop and set specifications for raw materials, intermediates, drug substance, excipients and drug product. Design and manage stability programs for non-GMP and cGMP drug substance and drug product batches and provide guidance for shelf-life and expiry dating. Establish workflows and procedures for analytical and quality control activities. Manage reference standards program, coordinate sourcing, ensure inventory, plan and execute testing and retesting activities, and manage shipments of reference standards. Author, review and approve various analytical reports in a timely manner to support drug substance and drug product development and manufacture, and regulatory filings. Support regulatory submissions by drafting and reviewing analytical sections of INDs, IMPDs, and NDAs, and ensure compliance with current regulatory requirements. Sometimes represent analytical function in CMC teams and project meetings, and work closely with cross-functional teams to meet project timelines and goals. Review/approve controlled cGMP documents, e.g., analytical methods and associated validation protocols/reports, specifications, stability protocols, change controls, LIRs, etc. Manage/perform QC review/approval of analytical test data for IPC testing, drug substance/product batch release and stability test data. Manage and review deviation events and OOS/OOT investigations in coordination with CMC counterparts, QA and regulatory team members. Contribute to the building of CMC infrastructure and company culture. Qualifications and Requirements D. with 8+ years of experience or BS or MS in chemistry or related discipline with 10-15 years of industry experience in an analytical chemistry setting. Good understanding and knowledge of pharmaceutical analytical methods and related issues. Experience with analytical development of small molecules and drug product oral dosage forms from preclinical to late-stage clinical development. Experience managing drug substance and drug product service providers in analytical matters. Extensive knowledge of GLP and cGMP requirements, appropriate regulatory guidance and current industry practices for analytical development. Experience in writing CMC sections for Regulatory submissions (IND experience required; NDA experience highly desirable). Excellent computer skills (e.g., Microsoft Office, Excel, Project). Ability to effectively manage multiple priorities and projects. Preference given to applicants able to work (hybrid) from Thousand Oaks or San Francisco, CA offices.
    $117k-184k yearly est. 5d ago
  • Clinical Research Physician Investigator

    Sansum Diabetes Research Institute 3.9company rating

    Principal research scientist job in Santa Barbara, CA

    Sansum Diabetes Research Institute has an opportunity for a full-time, board certified, or board-eligible Endocrinologist to serve as a Clinical Research Physician Investigator. SDRI is a non-profit organization and center of excellence with a mission to improve the lives of people impacted by diabetes through research, education, and clinical care. We are a preferred site for industry sponsored clinical trials, a testament to our exceptional research capabilities. On average, SDRI conducts 25+ trials per year, engaging approximately 1,000 participants. Current industry partners include Abbott, Dexcom, Insulet, Eli Lilly, Mannkind, Medtronic Diabetes, Novo Nordisk, Sanofi, Tandem Diabetes Care, and more. We are experts with experience across all study phases, and a broad portfolio of trials and clinical work focused on diabetes and metabolic health. Diversity and inclusivity are prioritized in in our clinical trials---in 2023, 30% of our research participants were from underrepresented populations. We are currently renovating our 18,000 square foot research facility to create a state-of-the-art center where we will accelerate life-changing diabetes research. Position Details: Responsible for 12+ Industry Sponsored Trials Per Year Design, Fund, and Execute Investigator Initiated Trials Develop Strategies and Partnerships to Drive Innovation Across the Enterprise Opportunity to Maintain a Clinical Practice through our Clinics Standard Office Hours Salaried Position: $250,000 - $350,000 Annually NOTE: The listed range is solely a base compensation for experienced full-time physician researchers. It does not include incentives and benefits. The base compensation rate may be adjusted based on training, community need and other possible determining factors. We Offer: Medical/Dental/Vision CME Stipend Malpractice Insurance Disability Retirement 403 (b) Annual Leave and Sick Time Licensure/DEA/Board Exam Fees PSLF Eligibility Requirements: MD or DO with Directly Related Experience in Endocrinology Board Certified or Board Eligible in Endocrinology DEA Certificate Eligible to Work in the United States, Must be in or Relocate to Santa Barbara, CA CA Licensure or the Ability to Obtain CA Licensure Interest in Research, Experience with Research preferred Exceptional Communication and Interpersonal Skills About Santa Barbara: Santa Barbara is known as The American Riviera thanks to its Spanish Colonial Revival architecture, rich heritage, world-renowned food and wine scene, stunning natural beauty and near-perfect weather. We invite you to learn more and to consider joining us at SDRI where you will join an experienced cross-functional team focused on developing and executing trials targeting innovation and excellence crossing drugs, devices, and technology that will impact the health span and life span of people living with diabetes.
    $90k-134k yearly est. 47d ago
  • Associate Scientist Analytical Chemistry

    Provivi 3.9company rating

    Principal research scientist job in Santa Monica, CA

    We are a multi-national, Santa Monica-based company, founded in 2013 by Caltech scholars: Professor Frances Arnold, Pedro Coelho, and Peter Meinhold. We're rethinking pest control as innovators in pheromone technology, the engineers and creators of a family of safe and effective pest control solutions for major damaging insects. We are hiring the very best and brightest people to expand our impact. Role Description As a member of the Provivi's technology team, you will have a vital role in developing and validating analytical methods for detection, identification, and quantification of small molecules found in Provivi's proprietary chemical and biochemical processes as well as pheromone components in formulated products. Specifically, the successful candidate will develop and validate GC, GCMS, HPLC, and HPIC methods, as well as establish quality control protocols for Provivi's commercial products, provide hands-on technical assistance to maintain analytical equipment in good working orders, and analyze samples supporting various projects. Strong technical, organizational, and communication skills, as well as the ability to develop creative solutions to challenging problems, are essential. Responsibilities Include Develops, validates, and standardizes GC, HPLC, HPIC analytical methods for detection, identification, and quantification of small molecules found in chemical and biochemical processes, and formulated products. Extracts, analyzes and evaluates material and products at all stages of development process under stringent quality and time requirements. Prepares research reports, invention disclosures, and Standard Operating Procedures for internal and external use. Reviews data for technical content and regulatory compliance. Ensures analytical equipment is maintained in good working order; troubleshoots and performs minor repairs as needed. Anticipates additional resources, consumables, and equipment requirements as needed to ensure that work can be completed within the budgeted time. Remains current with analytical chemistry literature and champions the implementation of new technology. Maintains a safe and orderly laboratory and ensures compliance with all safety policies and practices. Qualifications & Skills Include M.S. in analytical chemistry or equivalent, or bachelor's in chemistry with 2 additional years of analytical lab experience A minimum of 0-2 years of biotech and chemical industrial experience with hands-on experience in analytical chemistry. A good understanding of analytical chemistry, organic chemistry, and chemical engineering principles. Demonstrated practical ability to develop methods for isolation, characterization, and quantification of small molecules found in chemical and biochemical processes and formulated products using conventional chromatography techniques and analytical instruments including GC, GCMS, HPLC, and NMR. Must be skilled in operation of chromatographic data acquisition and processing software packages such as Chromeleon, ChemStation, and other software tools for data reduction and presentation. Excellent written, reporting, and verbal communication skills Proficient in using Microsoft Office suite including Word, Excel, and Power Point. Ability to prioritize responsibilities and multi-task in a fast-paced environment with changing priorities Must be highly motivated and capable of working independently to deliver results under tight deadlines Able to lift 15 - 40 pounds. Diversity and Equal Opportunity Employment Provivi is an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veterans status, or any other legally-protected factors.
    $76k-115k yearly est. 5d ago
  • Scientist - LC-MS Bioanalytical

    Amgen 4.8company rating

    Principal research scientist job in Thousand Oaks, CA

    Career CategoryScientificJob DescriptionJoin Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist - LC-MS Bioanalytical What you will do Let's do this. Let's change the world. In this vital role, you will support the design, development, validation, and implementation of robust LC-MS/MS bioanalytical methods for a wide range of therapeutic modalities-including small molecules, oligonucleotides, proteins, and other complex molecular entities-to enable GLP preclinical and regulated clinical studies. Given the scope of projects, the role will involve multidisciplinary interactions with scientists across research and development at Amgen. The position is lab-based, and has significant emphasis on data management/fidelity, report generation, effective time management, communication, and data presentation. Perform quantitative bioanalytical experiments and organize data and results, including planning and running LC-MS/MS bioanalysis and preparing and analyzing biological samples Develop and implement LC-MS/MS bioanalytical methods with quick turnaround times. Conduct small and large molecule bioanalysis in non-clinical and clinical samples from various matrices (plasma, urine, CSF, tissues). Perform biological sample extraction using protein crash (PPT), SPE, LLE, and/or affinity capture methodologies. Generate complete, accurate, and concise documentation using electronic systems and laboratory notebook Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines. Author study reports, standard operating procedures, analytical methods, memos, and other regulatory-compliant documents. Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings. Comply with safety guidelines and site-specific procedures which include but is not limited to the completion of training on assigned tasks, maintenance of training records, laboratory documentation, and following detailed SOPs and other written procedures. Perform general laboratory housekeeping activities and operational support as needed, including QC of reports. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional we seek is a [type of person] with these qualifications. Basic Qualifications: Doctorate degree PhD or PharmD or MD [and relevant post-doc where applicable] and 1-3 years of relevant industrial or postdoctoral experience Or Master's degree and 5 years of relevant industrial/technical experience Or Bachelor's degree and 7 years of relevant industrial/technical experience Preferred Qualifications: Prior experience in CRO or pharma/biotech strongly desired Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro-sampling Prior GLP and GCP experience. Demonstrated expertise in working with a variety of sample types (e.g., blood, plasma, serum, tissues, cerebrospinal fluid) and employing diverse sample preparation techniques (e.g., SPE, LLE, immunocapture) to support analysis of different therapeutic modalities, including small and large molecules by LC-MS. Prior experience in bioanalytical (regulated) assay execution and transfer to CROs Must be willing to work in a fast-paced, multi-project environment with high workload demands, and consistently deliver high-quality results within established timelines. Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively Excellent scientific problem-solving skills Excellent project and time management abilities Ability to work collaboratively with internal and external stakeholders Supervisory and mentoring experience in a lab-based setting What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team.careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. . Salary Range 117,067.00 USD - 135,735.00 USD
    $116k-158k yearly est. Auto-Apply 49d ago
  • Scientist - In Vivo Pharmacology

    Amgen Inc. 4.8company rating

    Principal research scientist job in Thousand Oaks, CA

    Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist - In Vivo Pharmacology What you will do Let's do this. Let's change the world. Amgen is seeking an enthusiastic, collaborative Scientist to join our In Vivo Pharmacology Team in the Oncology Therapeutic Area in Thousand Oaks, CA. In this vital role you will be responsible for generating and communicating pharmacology data to support the progression of oncology and immunotherapy research programs. Your responsibilities will be: * Designing, conducting, analyzing, and reporting in vivo and in vitro studies. * In vivo work will include rodent handling and procedures such as dosing (PO, SC, IP, IV), clinical health assessments and biologic sample collection. * In vitro work includes a range of cellular assays including multiparametric flow cytometry and molecular biology techniques to help interpret in vivo observations. * Operation and maintenance of laboratory equipment, accurate and timely record-keeping, and data analysis. * Active participation and presentation at cross-departmental teams and meetings. * The successful candidate will also be responsible for review and compliance with all applicable SOPs, business practices and company policies. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The [vital attribute] professional we seek is a [type of person] with these qualifications. Basic Qualifications: Doctorate degree or Master's degree and 2 or more years of In Vivo Pharmacology experience or Bachelor's degree and 4 or more years of In Vivo Pharmacology experience Preferred Qualifications: * PhD in related field and advanced and proficient understanding and use of technical principles, theories, and concepts. * Proficient in handling, manipulating and performing procedures with laboratory rodents. * Experience with rodent dosing via multiple routes (PO, SC, IP, IV). * Proven expertise in the analysis and interpretation of scientific data. * Highly motivated, collaborative and with excellent attention to detail. * Positive approach working in highly dynamic, team-based research environment. * Familiarity with oncology disease models. * Experience with multiparametric flow cytometry. * Good written and verbal communication skills. * Demonstrated technical aptitude and a strong work ethic. * Organizational and notebook/record keeping skills. * Computer literacy, e.g., GraphPad Prism, Excel, PowerPoint and Word. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: * A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts * A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan * Stock-based long-term incentives * Award-winning time-off plans * Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. . Salary Range 130,608.00 USD - 151,559.00 USD
    $116k-158k yearly est. 14d ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in San Buenaventura, CA?

The average principal research scientist in San Buenaventura, CA earns between $106,000 and $242,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in San Buenaventura, CA

$160,000
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