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  • Associate Scientist

    Planet Pharma 4.1company rating

    Principal research scientist job in Thousand Oaks, CA

    The Attribute Sciences Digital and Engineering (ASDE) group provides scientific and technical engineering expertise in support of pipeline and commercial portfolio. This team applies advanced data & computational analytics to advance products across all stages of therapeutic development. This position is part of the ASDE group and will support analytical assay templating and activity creation within Biovia electronic notebook system (ELN) for Attribute Science (AS) group within Process Development. Responsibilities will vary and include organizing and leading meetings with functional area teams to gather template, activity, and parser requirements. Once requirements are gathered the role will author, revise, and deploy assay templates and activities. Additional responsibility of the role will be implementing jobs aids, user support, and troubleshooting/revision post-release. Position Responsibilities: • Interface with scientists across AS organization to understand requirements for assay workflows. • Develop and maintain Biovia ELN assay templates and activities • Troubleshoot issues in collaboration with scientists, ELN Support team and Biovia. • Provide training and job aid documentation for scientists. Basic Qualifications • Master's degree OR • Bachelor's degree and 2 years of scientific or engineering experience OR • Associate's degree and 6 years of scientific or engineering experience OR • High school diploma / GED and 8 years of scientific or engineering experience Preferred Qualifications • Experience with execution of lab instrument assays • Experience with Biovia or other ELN software platforms • Proficiency with Excel for spreadsheet section in templates • Ensure FAIR data practices are followed when creating templates • Strong communication skills • Ability to deliver high quality results in a timely manner • Proactive in seeking feedback and engagement with teams • Strong attention to detail • Demonstrated ability to work under minimal direction • Ability to adapt to changing business needs • Ability to multi-task and function in a dynamic environment REMOTE ROLE
    $74k-113k yearly est. 3d ago
  • Formulation Scientist

    Amvac U.S 4.4company rating

    Principal research scientist job in Los Angeles, CA

    AMVAC, an American Vanguard company is a leading manufacturer and marketer of innovative solutions for the Ag industry in the areas of crop protection and nutrition, turf and ornamental management, and commercial pest control. We are looking for a Formulation Development Scientist with a passion for learning and creating value through unwavering customer focus, collaborative innovation, and responsible stewardship. This role will work with a top-notch team of scientists at our R&D facility located in Commerce, California. Job Duties & Responsibilities: Lead the design, prototyping, and advancement of innovative formulation strategies and delivery system technologies for active ingredients Collaborate cross-functionally with internal and external teams, including analytical sciences, process engineering, field product development, biological sciences, regulatory affairs, manufacturing, and commercial operations-to ensure seamless integration and success of formulation initiatives Staying abreast of new discoveries and technologies in the area of formulation and delivery system technologies Contribute to the generation of intellectual property, and prepare comprehensive technical documentation, including research reports and presentations Ensure compliance with laboratory safety procedures and best practices in experimental design and execution Skills & Qualifications: Solid background in formulation science with hands-on experience in areas such as colloidal systems, interfacial science, rheology, and material processing Prior hands-on experience in R&D Ability to work independently and drive projects to completion Strong collaborative and interpersonal skills with the ability to build effective working relationships across diverse teams Skilled in cross-functional collaboration, engaging with colleagues and stakeholders from various technical and business backgrounds Excellent verbal and written communication skills; specifically, the ability to persuade/influence others of the value of AMVAC technology and to clearly articulate the value of technology when talking with customers Working knowledge of formulation design & development and global regulatory product registration process Education Requirements: PhD Chemistry Preferred Bachelors Degree in Chemistry, Chemical Engineering, Material Science, or related fields required; Master's Degree MS ChE / Material Science preferred Experience Requirements: 7+ yrs. industry experience Colloid & Surface science, Surfactant chemistry, rheology expertise Raman microscopy, granular formulation development, encapsulation techniques Manufacturing scale-up experience in the chemicals or related industry Benefits & more: We offer a work environment that values diversity and inclusion, promotes continuous learning and professional growth, and supports a healthy work-life balance to empower team members Exceptional Health insurance including Medical, Dental, and Vision offered at low cost to employees and their families Life; AD&D insurance for employees and their families 401(k) Retirement Savings Plan with employer matching Employee Stock Purchasing Plan (ESPP) with employee discount [AMVAC is an American Vanguard Company (NYSE: AVD)] Health Savings Account (HSA) / Flexible Spending Account (FSA) available Salary range : $120K - $150K - not including bonus and other compensation Wellness program; tuition reimbursement and other benefits We are an Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, or any other characteristic protected by law. AMVAC is proud to be an EEO/AA employer M/F/D/V. We maintain a drug-free workplace and perform pre-employment background checks and substance abuse testing. We participate in the E-Verify Federal Identification System. AMVAC, An American Vanguard Company, (NYSE: AVD)
    $120k-150k yearly 1d ago
  • Senior Applied AI Scientist

    Cisco Systems, Inc. 4.8company rating

    Principal research scientist job in Santa Monica, CA

    Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Simply put - we power the future. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.
    $199.7k-292.8k yearly 17d ago
  • 3D Generative AI Research Scientist

    The Walt Disney Company 4.6company rating

    Principal research scientist job in Glendale, CA

    About the Role & Team “Any sufficiently complex technology is indistinguishable from magic.” - Arthur C. Clarke At Imagineering, we are constantly exploring new ways to connect with our guests - to surprise them, make them smile, and open their minds to magic - not just in our parks and resorts, but everywhere around the world. At Walt Disney Imagineering Research and Development this "magic" emerges from the application of world-class technology and everything from new Guest-facing experiences to new tools for Imagineers and Cast Members who power our parks and bring that magic to life. Our team of engineers, designers, artists and scientists share a passion for solving impossible problems and building ground-breaking experiences. At Disney Research Imagineering, we pursue and apply the science behind the magic: unlocking new opportunities for Imagineering in all aspects of project lifecycles, from early phase creative ideation to deployment. We are seeking a Research Scientist to lead foundational and applied research at the intersection of artificial intelligence and spatial media. This role involves designing, developing, and deploying cutting-edge generative models to support creative, architectural, and experiential design workflows across Disney's themed entertainment portfolio. As a key scientific contributor and thought leader, you will collaborate with cross-functional teams of researchers, engineers, and creatives. Your work will span exploratory investigations, peer-reviewed research, and the translation of experimental technologies into applied tools for design and fabrication. You will report to the Associate Lab Director and contribute to the AI/ML research strategy for Imagineering R&D. This is a full-time role. What You Will Do Conduct original research in generative AI, focusing on 3D model generation, scene synthesis, and simulation. Develop machine learning architectures and algorithms that enhance the creation, visualization, and physical realization of themed environments. Prototype AI-driven systems that support CAD/BIM workflows, virtual production, and spatial design. Integrate AI with real-time rendering engines, 3D modeling pipelines, and mixed-reality platforms. Evaluate generative models for feasibility, fidelity, controllability, and integration into creative pipelines. Collaborate with internal and external research partners, including academic institutions, industry labs, and vendors. Translate scientific insights into working prototypes that bridge digital design and physical implementation. Mentor junior researchers and contribute to the technical direction of AI initiatives within the lab. Required Qualifications & Skills 5+ years of research experience in machine learning, computer vision, or computational graphics with published work in top-tier conferences/journals (e.g. SIGGRAPH, NeurIPS, CVPR, and others). Expertise in generative 3D AI technologies such as NeRFs, diffusion models, implicit neural representations, or volumetric rendering. Proficiency in machine learning libraries (e.g., PyTorch, TensorFlow) and programming languages such as Python and C++. Experience working with 3D asset creation and rendering tools (e.g., Blender, Unreal Engine, Unity, Houdini). Deep understanding of data-driven design tools and interactive AI systems for spatial computing or immersive storytelling. Demonstrated ability to bridge theoretical research with real-world implementation. Strong communication skills with the ability to present complex ideas to multidisciplinary teams. A desire to work in a creative environment where technical and creative experts collaborate and challenge each other every day to achieve truly groundbreaking solutions Preferred Qualifications Familiarity with robotics, digital fabrication, or construction automation as it relates to AI integration. Experience with AI-assisted tools in architecture, entertainment, or XR applications. Background in physical simulation, procedural modeling, or multimodal (text-to-3D) generation. Track record of technology transfer, patents, or deployed AI systems. Experience with generative models for animation, such as motion transformers, motion diffusion models, variational motion encoders, or reinforcement learning for animated control. Experience integrating animation systems into real-time engines (e.g., Unreal Engine with Control Rig, Unity with Mecanim or custom solutions). Familiarity with motion capture data pipelines, retargeting techniques, and animation blending. Demonstrated ability to bridge technical research and production-quality animation systems, ideally through previous work in film, games, or immersive media. Contributions to open-source projects or prior internships in research labs or innovation teams. Interest in construction tech, architecture, or fabrication workflows is a plus. Education PhD required in Computer Science, Electrical Engineering, Computational Design, or a related field, with specialization in AI/ML or 3D graphics. Additional Information Benefits and Perks: Disney offers a rewards package to help you live your best life. This includes health and savings benefits, educational opportunities, and special extras that only Disney can provide. Learn more about our benefits and perks at **************************************** #DXMedia #LI-KK2 The hiring range for this position in Glendale, CA is $167,700 to $224,900 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. A bonus and/or long-term incentive units may be provided as part of the compensation package, in addition to the full range of medical, financial, and/or other benefits, dependent on the level and position offered. Job Posting Segment: WDI R&D and Tech Studio Job Posting Primary Business: R&D and Tech Studio (WDI) Primary Job Posting Category: Research Science Employment Type: Full time Primary City, State, Region, Postal Code: Glendale, CA, USA Alternate City, State, Region, Postal Code: Date Posted: 2025-07-09
    $167.7k-224.9k yearly Auto-Apply 60d+ ago
  • Research Scientist

    Tpirc

    Principal research scientist job in Long Beach, CA

    Job Description Job Title: Research Scientist Focus: Cell Biology, Molecular Biology, and Pulmonology Reports To: Director of Research Job purpose: The Research Scientist will advance translational programs in pulmonology, bronchopulmonary dysplasia, and cystic fibrosis. This role will design and lead laboratory studies that bridge bench discovery with patient-derived datasets in a collaborative, fast-paced research environment. Duties and Responsibilities: Lead independent and collaborative research projects focused on pulmonary immunology, epithelial biology, or inflammatory disease mechanisms. Characterize phenotypes and functions of immune and structural cell populations from patient and animal sources. Design experimental approaches and supervise technical staff or junior scientists as needed. Optimize assays for immune cell isolation, culture, and activation. Perform molecular and histological characterization of lung development and injury models. Contribute to manuscript preparation, grant applications, and cross-functional project reviews. Maintain organized experimental records and oversee reagent/supply management. Qualifications: Ph.D. in Biological Sciences, Molecular/Cell Biology, Pulmonary Biology, or a related discipline. Demonstrated record of productivity (publications, patents, or leadership of projects). Hands-on experience with Luminex multiplex assays, flow cytometry, immunoassays (ELISA), Western blotting, and molecular cloning. Skilled in mammalian cell culture, viral vector production/transduction, and qPCR. Experience with lung histopathology, immunofluorescence, or morphometric analysis preferred. Excellent written and oral communication skills, and ability to work effectively in multidisciplinary teams. Comfortable in a dynamic, translational research environment where projects evolve rapidly. Physical requirements: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to talk or hear. The employee frequently is required to stand; walk; use hands to finger, handle or feel; and reach with hands and arms. The employee is required to walk between multiple office locations that include the use of stairs (elevator is only available in some instances). This position requires the ability to occasionally lift office products and supplies, up to 20 pounds. Direct reports: N/A The company provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, marital status, veteran status, or any other consideration made unlawful by federal, state, or local laws. The company is committed to providing reasonable accommodation for qualified applicants, and employees with disabilities to ensure they enjoy equal access to all employment opportunities and benefits of employment as required by the Americans with Disabilities Act.
    $90k-151k yearly est. 18d ago
  • Research Scientist - Controlled 3D Generation

    Stability.Ai

    Principal research scientist job in Los Angeles, CA

    About the Role We're seeking a Research Scientist passionate about 3D generation, flow matching, and diffusion models. You'll help advance the frontier of controllable 3D content creation-building models that generate consistent, editable, and physically grounded 3D assets and scenes. What You'll Do * Conduct cutting-edge research on flow-matching, diffusion, and score-based methods for 3D generation and reconstruction. * Design and implement scalable training pipelines for controllable 3D generation (meshes, Gaussians, NeRFs, voxels, implicit fields). * Develop techniques for conditioning and control (text, sketch, pose, camera, physics) and multi-view consistency. * Analyse model behaviour through ablations, visualisations, and quantitative metrics. * Collaborate with cross-disciplinary research, graphics, and infrastructure teams to translate research into production-ready systems. * Publish results at top-tier venues and work with interns. What You Bring * PhD (or equivalent experience) in Machine Learning, Computer Vision, or Computer Graphics. * Published work on diffusion, flow-matching, or score-based generative models (2D or 3D). * Strong engineering and problem-solving abilities: experience with PyTorch, JAX, or CUDA-level optimisation. * Understanding of 3D representations (meshes, Gaussians, signed-distance fields, volumetric grids, implicit networks). * Solid grasp of geometry processing, multi-view consistency, and differentiable rendering. * Ability to scale experiments efficiently and communicate complex results clearly. Bonus / Preferred * Experience generating coherent 3D scenes with multiple interacting objects, lighting, and spatial layout. * Familiarity with scene-level control (object placement, camera path, simulation, or text-to-scene composition). * Knowledge of video-to-3D, image-to-scene, or 4D temporal generation. * Background in physically-based rendering, simulation, or world-model architectures. * Track record of impactful publications or open-source releases. Equal Employment Opportunity: We are an equal opportunity employer and do not discriminate on the basis of race, religion, national origin, gender, sexual orientation, age, veteran status, disability or other legally protected statuses.
    $91k-152k yearly est. Auto-Apply 29d ago
  • Research Scientist

    California Institute of Technology 4.5company rating

    Principal research scientist job in Pasadena, CA

    Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community. Job Summary Research Scientist Position - SPHEREx Cosmology (Caltech) The Caltech SPHEREx team is seeking a research scientist to contribute to the scientific analysis of data from the SPHEREx mission. The successful candidate will work closely with the SPHEREx Science Team and is expected to become a full member of the team by SPHEREx first major release, participating actively in the mission's core science programs. More information about SPHEREx can be found at **************** caltech. edu. Essential Job Duties The primary focus of the position is the development of high-level cosmological analyses necessary to extract scientific results from SPHEREx's spectroscopic galaxy catalog. This includes (as needed) methodological and theoretical development, as well as significant software implementation. Expertise in one or more of the following areas is especially valued: large-scale structure and clustering measurements, higher-order statistics, systematic error mitigation, cosmological simulations, and pipeline development and validation. The candidate will integrate and work closely with the SPHEREx team so good collaboration skills are important for this job. Basic Qualifications Ph. D. (or equivalent), or PhD in progress, in astrophysics, cosmology, or a related field. Preferred Qualifications Strong record of original research in large-scale structure or cosmology. Demonstrated experience in software development for scientific analysis. Required Documents Resume Cover Letter Reference letters should be sent to Nancy Rappard nrappard@caltech. edu with email title "SPHEREx Cosmology position"
    $74k-114k yearly est. 60d+ ago
  • Research Scientist, Self-Replication

    Gram

    Principal research scientist job in El Segundo, CA

    The Mission At GRAM, we believe the next great leap for humanity will be physical, not digital. What AGI is to bits, Self-Replication (SR) is to atoms. As an SR research and deployment company, our mission is to make humanity galactic by enabling physical exponential growth. To achieve this, we are conducting foundational research across general-purpose robotics, artificial intelligence, biology, and materials science to enable SR within our lifetimes. Our first step is to challenge the consensus that robots should look like us. We believe true progress comes from optimizing for function over form. We are creating a new embodiment for intelligence, designed from first principles to build the future physical economy, on and off-world. The Role Self-Replication is to the physical world what AGI is to the digital: a foundational, recursively improving capability with a vast and undefined ceiling. The person in this role will not merely apply known principles; they are responsible for discovering the fundamental laws and architecting the core intelligence of this new paradigm. This is an opportunity to define a field. Your work will be to answer one of the most profound questions in technology: how does a system build a system? The scope of this question is not limited to a single machine. It encompasses the entire chain of logistics, energy, manipulation, and assembly required for a technological ecosystem to grow. Your research will form the bedrock upon which our engineering teams build the future, shaping not just our products, but the very economic and industrial logic of our expansion into the solar system. This role requires a unique combination of scientific rigor, strategic foresight, and architectural vision. We are looking for a singular mind to lead this charge, establishing a research program from the ground up with the resources and mandate to pursue a multi-decade mission that will alter the course of human history. Key Responsibilities: Architect the foundational thesis for Self-Replication at GRAM, creating the intellectual framework that distinguishes our pragmatic, systems-based approach from all other efforts in the field. Develop the physical genome for all GRAM hardware. This involves establishing the core design principles that ensure our systems are intrinsically capable of being built, assembled, and maintained by other machines. Lead the conceptual design of "GAIA," the governing intelligence for planetary scale industrial automation, resource allocation, and the expression of collective human ambition. Act as a key strategic partner to the CEO, translating the company's grand vision into an actionable, multi-decade technical roadmap. Serve as the company's foremost thought leader on SR, acting as a magnet for attracting a world class team of scientists and engineers. About You Your mind operates on two levels simultaneously. On one, you are a physicist and theorist, comfortable with the highest levels of abstraction in information theory, economics, and complex systems. On the other, you are a pragmatic systems thinker with an unnerving intuition for how the real world industrial machine, with all its constraints, inefficiencies, and gritty complexities, actually works. You are driven not just by the pursuit of knowledge, but by the desire to build the systems that will reshape civilization. You are not just a researcher; you are the architect of a new economic and industrial paradigm. Basic Qualifications: A PhD in Physics, Computer Science, Systems Engineering, or a related discipline. A history of conceiving and driving forward large scale, open ended, and audacious projects, either in academia or industry. A demonstrable, deep understanding of complex systems, whether industrial, economic, or biological. The ability to create and communicate a compelling, long term technical vision. Preferred Qualifications: A body of work (publications, patents, or a portfolio of private projects) that points to a sustained intellectual obsession with large scale systems, automation, or the future of industrial technology. Experience in a strategic role that required bridging the gap between frontier R&D and practical engineering or business constraints. The ability to develop and defend a multi decade technical roadmap to investors, partners, and employees. A fundamental, first principles approach to problem solving that is not constrained by existing disciplines or dogma. Location This is an on-site role at our research lab in El Segundo, California. We offer significant relocation assistance for exceptional candidates. Interview Process After submitting your application, we review your portfolio and any exceptional work you've shipped. If your application demonstrates the caliber we seek, you'll enter our interview process, which is designed for speed and substance. We aim to complete it within one week from start to finish. Compensation Your total compensation reflects both the significance of early-stage equity and competitive market rates. The following is the general framework for all roles at GRAM. Company-Wide Base Salary Range: $75,000 - $300,000 USD, calibrated to your impact potential Equity: Substantial ownership stake befitting founding team members Benefits: Health, dental, and vision coverage; all meals are paid for; relocation assistance GRAM is an equal opportunity employer. We evaluate solely on capability and drive. Why Join? We are an early, focused team of scientists and engineers building the system that builds itself. GRAM is funded by leading investors and long-term visionaries. We operate without bureaucracy. Ownership and leadership flow to those who demonstrate exceptional capability, and every team member works directly on our core technology. We are based in El Segundo, the heart of America's industrial future, focused on solving one of the most important problems of our time.
    $91k-152k yearly est. Auto-Apply 60d+ ago
  • Research Scientist, Adhesion

    Galactic Resource Advancement Mechanism Technologies Corporation

    Principal research scientist job in El Segundo, CA

    Job Description The Mission At GRAM, we believe the next great leap for humanity will be physical, not digital. What AGI is to bits, Self-Replication (SR) is to atoms. As an SR research and deployment company, our mission is to make humanity galactic by enabling physical exponential growth. To achieve this, we are conducting foundational research across general-purpose robotics, artificial intelligence, biology, and materials science to enable SR within our lifetimes. Our first step is to challenge the consensus that robots should look like us. We believe true progress comes from optimizing for function over form. We are creating a new embodiment for intelligence, designed from first principles to build the future physical economy, on and off-world. The Role At GRAM, our engineering is built on a foundation of scientific discovery. This role is for the scientists who work at the frontier, creating the fundamental breakthroughs that will enable our future technology. You will be responsible for tackling high-risk, high-reward challenges, transforming nascent scientific principles into tangible, ownable advantages that redefine what is possible. The ability to adhere to any surface is more than a feature; it is a foundational capability for a galactic species. Your breakthroughs in adhesion will grant our machines purchase on any foothold, enabling them to crawl across the irradiated skin of a starship, cling to the sheer, unprocessed rock of an alien cliffside, or anchor themselves to the shifting crystalline ores of a deep-space mining operation. This is an opportunity to solve adhesion not just for one robot, but for the billions of machines that will build our multi-planet economy. Your work will form the bedrock upon which our engineering teams build the future. This is a chance to build a research program from the ground up, with the resources and mandate to pursue your curiosity in service of an ambitious, long-term mission. Key Responsibilities: Architect and own GRAM's entire research program for surface-agnostic adhesion, creating the foundational technology for mobility in zero-g and extra-terrestrial environments. Lead the development of novel adhesion systems, from first-principles discovery and materials science to fully-integrated, patentable hardware ready for deployment on our robots. Develop a strategic research roadmap, identifying and de-risking the most promising technological pathways, whether they be electromagnetic, electrostatic, or bio-mimetic. Personally drive the design, fabrication, and rigorous testing of experimental prototypes, establishing the empirical truth that will guide our engineering direction. Act as a deeply embedded, multi-disciplinary partner to our engineering teams, ensuring the seamless integration of your systems into a cohesive and functional robot. About You You are a first-principles thinker who is energized by solving problems that have no playbook. You are drawn to ambitious, long-term missions and want to build technology that fundamentally changes our physical capabilities. You thrive in a high-agency environment where you are given the ownership and resources to tackle core challenges. You have a demonstrated ability to deliver tangible results on high-stakes, open-ended research problems. Basic Qualifications: A PhD in Experimental Physics, Materials Science, Mechatronics, or a related discipline, OR an MS with an exceptional portfolio of inventive, first-of-its-kind hardware. A track record of turning a scientific concept into a functional, physical prototype. Deep theoretical knowledge in a relevant field, such as electromagnetism, materials science, or contact physics. Hands-on experience with fabrication, experimental design, and data analysis. Preferred Qualifications: A portfolio of patents and/or first-author publications in premier scientific journals. Direct experience developing hardware for extreme environments (e.g., vacuum, high-radiation, extreme temperatures). Experience leading a small, high-stakes R&D project from concept to delivery. Proficiency with multiphysics simulation tools (e.g., COMSOL, Ansys). A "full-stack" research capability, from theory and simulation to CAD, prototyping, and testing. Location This is an on-site role at our research lab in El Segundo, California. We offer significant relocation assistance for exceptional candidates. Interview Process After submitting your application, we review your portfolio and any exceptional work you've shipped. If your application demonstrates the caliber we seek, you'll enter our interview process, which is designed for speed and substance. We aim to complete it within one week from start to finish. Compensation Your total compensation reflects both the significance of early-stage equity and competitive market rates. The following is the general framework for all roles at GRAM. Company-Wide Base Salary Range: $75,000 - $300,000 USD, calibrated to your impact potential Equity: Substantial ownership stake befitting founding team members Benefits: Health, dental, and vision coverage; all meals are paid for; relocation assistance GRAM is an equal opportunity employer. We evaluate solely on capability and drive. Why Join? We are an early, focused team of scientists and engineers building the system that builds itself. GRAM is funded by leading investors and long-term visionaries. We operate without bureaucracy. Ownership and leadership flow to those who demonstrate exceptional capability, and every team member works directly on our core technology. We are based in El Segundo, the heart of America's industrial future, focused on solving one of the most important problems of our time.
    $91k-152k yearly est. 28d ago
  • Postdoctoral Scientist - Smidt Heart Institute (Chugh Lab)

    Dev 4.2company rating

    Principal research scientist job in Malibu, CA

    Company DescriptionJobs for Humanity is partnering with CEDARS-SINAI to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located. Company Name: CEDARS-SINAI Job Description Grow your career at Cedars-Sinai! The Smidt Heart Institute reflects Cedars-Sinai's steadfast dedication to heart disease and research innovation giving patients access to the highest level of care. Year after year, thousands of people trust their hearts to Smidt Heart Institute at Cedars-Sinai. Our cardiologists, cardiac surgeons and niche care teams treat the full spectrum of heart disease and disorders, while our investigators continue to advance the field with groundbreaking, life-saving research. From genetic counseling and targeted drug therapies to a growing array of minimally invasive procedures, Cedars-Sinai continues to stand at the forefront of technology, innovation and discovery improving patient outcomes. Join our team and use your experience with an organization known nationally for excellence in research! JOB SUMMARY: Working independently but in close cooperation and in consultation with the Director, Center for Cardiac Arrest Prevention (CCAP), the Research Fellow will be involved in new and ongoing projects at the CCAP. Funded by grants from NIH/NHLBI, the mission of the CCAP is to discover and implement novel clinical tools for prediction and prevention of sudden cardiac arrest, thereby reducing the burden of sudden cardiac death in the community CCAP. Unique opportunities to analyze existing data and publish papers. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds. ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: - May assist in preparation of grant proposals but is not responsible for generating grant funds. - May participate in publications and presentations as author or co-author. - Designs and performs analyses independently or semi-independently. Will keep appropriate experimental records and documentation and discuss the results with the Principal Investigator. - May develop, adapt, and implement new research techniques and protocols. - Analyzes, interprets, summarizes and compiles data. - Performs routine and complex analyses throughout training period. - May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed. Educational Requirements: Doctorate (MD) plus clinical cardiology/clinical electrophysiology sub-specialty clinical training for at least two years. Experience: - 1 year experience acquired thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment - Should have written and published scientific papers. - Has demonstrated aptitude to ask research questions and successfully published papers and/or had grants funded. Physical Demands: - Able to perform moderate lifting. - Able to sit, stand and walk for prolonged periods of time. - Able to read papers and online documents. - Able to operate standard office equipment. - Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions. Working Title: Postdoctoral Scientist - Smidt Heart Institute (Chugh Lab) Department: Heart Institute Operations Business Entity: Cedars-Sinai Medical Center Job Category: Academic/Research Job Specialty: Postdoctoral Position Type: Full-time Shift Length: 8 hour shift Shift Type: Day Base Pay:$64,500.00 - $93,600.00
    $64.5k-93.6k yearly 60d+ ago
  • Product Excellence & Sensory Scientist

    DHD Consulting 4.3company rating

    Principal research scientist job in Buena Park, CA

    Language Requirement: No Korean language skills required This role focuses on conducting sensory evaluations to ensure product quality within the New Product Development (NPD) process. The position also involves supporting R&D budget control and administrative tasks. Key Responsibilities: Conduct sensory evaluations to assess food product attributes for NPD and product excellence management. Organize, train, and maintain sensory panels for accurate data collection. Analyze sensory data and provide insights to guide product development. Collaborate with Marketing and other teams to align sensory insights with product strategies. Stay updated on industry trends and sensory evaluation techniques. Communicate sensory findings to food scientists and stakeholders. Support R&D budget monitoring and administrative tasks. Research industry trends and competitors to ensure market competitiveness. Qualifications: Bachelors degree in Food Science or a related field. 3+ years of experience in sensory evaluation within the food industry. Experience in food product development is a plus. Excellent communication and organizational skills. Proficiency in MS Office. Ability to manage tasks independently with minimal supervision. Strong attention to detail and ability to handle confidential information.
    $84k-120k yearly est. 60d+ ago
  • Applied Scientist, Generative AI/ML

    Adobe Systems Incorporated 4.8company rating

    Principal research scientist job in Los Angeles, CA

    Our Company Changing the world through digital experiences is what Adobe's all about. We give everyone-from emerging artists to global brands-everything they need to design and deliver exceptional digital experiences! We're passionate about empowering people to create beautiful and powerful images, videos, and apps, and transform how companies interact with customers across every screen. We're on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We realize that new ideas can come from everywhere in the organization, and we know the next big idea could be yours! The Opportunity Adobe is seeking to add Applied Scientists in Generative AI to our world-class AI Platform team. We are specifically looking for scientists with expertise in preparing data, training, fine-tuning and adapting large foundation models across all modalities: images, video, 3D, LLMs and cross-modal setups. We welcome outstanding candidates in all related technical fields, such as Machine Learning, Deep Learning, Computer Vision, and Natural Language Processing. The related applications include image/video/3D generation, editing, and understanding, conditioned on controls stemming from large language models, or other innovative interactions tailored for creative workflows, and multimodal priors. What You'll Do * Conduct pioneering research and development in Generative AI for visual (image/video/3D), audio, and multi-modal outputs. * Develop and deploy novel generative AI technologies to existing and new Adobe Products. * Research and develop novel large-scale foundation models with deep reasoning and world-building capabilities. * Collaborate with world-class researchers and ML engineers to bring research ideas to creative workflows used by millions. * Publish and present your work in world-class scientific venues in CV/AI/ML/CG fields Required Qualifications * Ph.D. in Computer Science, CV/AI/ML/CG or related fields and 1+ years professional experience. * Research or industry experience in training Generative AI models (pre-training and/or post-training) in at least one of the following modalities: image, video, 3D, or audio. * Expertise in large-scale model training and optimization, including data curation, distributed training, and memory-efficient techniques. * Experience with post-training techniques such as fine-tuning, alignment or distillation. * Proficiency with modern deep learning frameworks (e.g., PyTorch) and experience scaling models on GPU/TPU clusters. * Excellent communication skills and a strong great teammate What You'll Bring * Experience on large-scale generative model training * Experience on synthetic data generation * Experience of working with large-scale datasets * Experience of working with product teams on technology transfers #FireflyGenAI Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The U.S. pay range for this position is $142,700 -- $257,600 annually. Pay within this range varies by work location and may also depend on job-related knowledge, skills, and experience. Your recruiter can share more about the specific salary range for the job location during the hiring process. At Adobe, for sales roles starting salaries are expressed as total target compensation (TTC = base + commission), and short-term incentives are in the form of sales commission plans. Non-sales roles starting salaries are expressed as base salary and short-term incentives are in the form of the Annual Incentive Plan (AIP). In addition, certain roles may be eligible for long-term incentives in the form of a new hire equity award. State-Specific Notices: California: Fair Chance Ordinances Adobe will consider qualified applicants with arrest or conviction records for employment in accordance with state and local laws and "fair chance" ordinances. Colorado: Application Window Notice There is no deadline to apply to this job posting because Adobe accepts applications for this role on an ongoing basis. The posting will remain open based on hiring needs and position availability. Massachusetts: Massachusetts Legal Notice It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Adobe is proud to be an Equal Employment Opportunity employer. We do not discriminate based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Learn more. Adobe aims to make Adobe.com accessible to any and all users. If you have a disability or special need that requires accommodation to navigate our website or complete the application process, email accommodations@adobe.com or call **************.
    $142.7k-257.6k yearly 60d+ ago
  • Associate Scientist

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Thousand Oaks, CA

    Ideal candidates worked in labs before to understand the scientific terminology required to support staff in a multitude of assays. This position will be responsible for gathering requirements from scientists and recording them in a notebook or digital recipe. Communication, detail oriented, organized, experience working with multiple stakeholders, and managing multiple projects with minimal oversight. Attribute Sciences Digital and Engineering (ASDE) group provides scientific and technical engineering expertise in support of pipeline and commercial portfolio. This team applies advanced data & computational analytics to advance products across all stages of therapeutic development. Position is part of the ASDE group and will support analytical assay templating and activity creation within Biovia electronic notebook system (ELN) for Attribute Science (AS) group within Process Development. Responsibilities will vary and include organizing and leading meetings with functional area teams to gather template, activity, and parser requirements. Once requirements are gathered the role will author, revise, and deploy assay templates and activities. Additional responsibility of the role will be implementing jobs aids, user support, and troubleshooting/revision post-release. **Position Responsibilities:** + Interface with scientists across organizations to understand requirements for assay workflows. + Develop and maintain Biovia ELN assay templates and activities + Troubleshoot issues in collaboration with scientists, ELN Support team and Biovia. + Provide training and job aid documentation for scientists. **Basic Qualifications:** + Master's degree OR + Bachelor's degree and 2 years of scientific or engineering experience OR + Associate's degree and 6 years of scientific or engineering experience OR + High school diploma / GED and 8 years of scientific or engineering experience **Preferred Qualifications:** + Experience with execution of lab instrument assays + Experience with Biovia or other ELN software platforms + Proficiency with Excel for spreadsheet section in templates + Ensure FAIR data practices are followed when creating templates + Strong communication skills + Ability to deliver high quality results in a timely manner + Proactive in seeking feedback and engagement with teams + Strong attention to detail + Demonstrated ability to work under minimal direction + Ability to adapt to changing business needs + Ability to multi-task and function in a dynamic environment **Must Have Skill Sets:** + Lab assay experience and understanding of scientific processes + Experience with ELN notebooks - Biovia preferred + Excel and data management skills **Day to Day Responsibilities:** + Creating activities and templates in the Biovia system + User support and troubleshooting + Hosting meetings and requirements gathering **About US Tech Solutions:** US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit *********************** . "US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran"
    $67k-101k yearly est. 9d ago
  • EHS Associate Scientist

    Weston Solutions Inc. 4.5company rating

    Principal research scientist job in Los Angeles, CA

    At Weston Solutions, Inc. you will do meaningful work and make valuable contributions. Employee-ownership at Weston is a path to professional growth and access to diverse opportunities in a highly connected community that works together across key service areas to make a difference in the environment. Weston continues to evolve and adapt to our changing world as a premier provider of environmental and infrastructure services for over sixty years. In both the public and private sectors our teams help identify, solve, mitigate, and manage critical environmental issues to help clients achieve a more sustainable future. This EHS Associate Scientist role supports Environmental Health & Safety (EHS) initiatives as a hands-on technical contributor, working either as part of a consulting team or embedded with client staff. You'll help design and implement EHS programs, conduct assessments, and provide regulatory guidance, while also beginning to support business development and client relationship management. The position involves solving routine EHS challenges, preparing reports, coordinating logistics, and may include mentoring junior staff-all with a strong focus on delivering high-quality service and building client trust. Location: California Expected Outcomes: * Conduct facility inspections, sampling, and assessments to identify hazards and ensure regulatory compliance. * Develop, implement, and maintain EHS programs, procedures, and documentation. * Investigate incidents and recommend corrective actions. * Provide regulatory guidance, technical support, and onsite safety services. * Deliver EHS training and support ergonomic evaluations. * Independently plan and prioritize work; coordinate with teams and manage logistics. * Analyze data to support decision-making and regulatory interpretation. * Prepare accurate reports and proposals aligned with quality standards. * Communicate professionally with clients, regulators, and internal teams. * Support business development through client engagement and proposal contributions. * May supervise or assist junior staff. * Adhere to company policies and ensure high-quality deliverables. * May require travel, use of PPE, and work in physically demanding or hazardous environments. Knowledge, Skills & Abilities: * Bachelor's degree in science/engineering or equivalent experience. * 1-5 years of relevant EHS experience; advanced degrees may substitute. * Should hold or be actively working toward: ASP, CHMM, CBCA, EIT. * Strong knowledge of EHS regulations, environmental issues, and permitting. * Familiarity with health & safety programs, industrial hygiene (IH), ergonomics, and emergency response. * Experience with regulatory agencies (OSHA, EPA) and ISO standards. * Skilled in environmental sampling, data analysis, and technical reporting. * Strong communication, presentation, and teamwork skills. * Proficient in Microsoft Office and relevant tools. We fully invest in our people: Weston provides a generous, comprehensive benefits package program that offers employees high value options with solid financial protection, meeting the personal needs of its people and their families. * Medical, Dental, Vision, 401K with base and matching employer stock contributions. * Paid time off including personal, holiday, and parental leave. * Life and disability plans. * Critical illness and accident plans. * Work/Life flexibility. * Professional development opportunities. Compensation will vary based upon experience, education, skill level, and other compensable factors.
    $66k-95k yearly est. Auto-Apply 22d ago
  • Sr. Bioinformatics Scientist II

    Fulgent Genetics, Inc. 4.2company rating

    Principal research scientist job in El Monte, CA

    About Us Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform. Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike. Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company. Summary of Position As a Senior Bioinformatics Scientist II, you will collaborate in cross-functional teams to design, implement and continually improve advanced computational pipelines for high-throughput analysis of multiple types of NGS data. You will work independently in refining methodologies for data analysis, processing, visualization and storage. You will also be assigned leadership roles in projects with mentor responsibility to junior members of the team. You will strive to maximize efficiency, quality, reliability and customer usability and satisfaction. Key Job Elements Research and Development Investigate and refine available algorithms, methods and data sources. Work independently to define, prioritize and complete objectives to meet company goals. Make recommendations for pipeline component improvements, or new pipelines. Write SOPs for new or updated pipeline components, or new pipelines. Write specifications for implementation by software developers. Oversee pipeline development and integration. Production and Customer Support Investigate and resolve analysis and pipeline production issues. Review client projects for compatibility with current pipelines, make recommendations and implement customizations as needed. Oversee sequencing service projects, ensuring timely processing, quality results and client satisfaction. Support software and LIMS developers in automation efforts. Perform specialized analyses as needed for specific projects. Keep up-to-date with current best practices and emerging methods. Treat data with a high level of integrity and ethics. Data Maintenance Investigate available annotation and reference data sources. Validate and deploy/update selected data sources. Write reports detailing validation/update methodology and results. Write SOPs for updating existing or new data sources. Validation Develop appropriate procedures for testing and validation of new or updated pipelines or pipeline components. Document and maintain data used for testing and validation. Write validation reports detailing validation methodology and results. Knowledge/Experience * Ph.D. degree from an accredited institution in Bioinformatics, Biostatistics or related field. * 10+ years of experience in a related scientific discipline (Bioinformatics preferred). * Demonstrated mastery of Fulgent specific methods and processes. * Experience analyzing multiple types of next-generation sequencing (NGS) data * Expertise with statistics for big data analysis and multiomics data integration. * Expert level hands-on skills in bioinformatics databases and tools. * Expert level in relevant programming languages, preferably Scala, Java, Python, and Bash. * Must enjoy working in a multi-disciplinary and collaborative environment. * Ability to troubleshoot both individually and as part of a team. * Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner. * Experience in team software development and integration projects is a plus. Technical Leadership: * Provide technical leadership to the team * Be the mentor for junior team members. Supervisory Responsibilities * None Reports To * Director of Bioinformatics Environment Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term "qualified individual with a disability" means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position. For California residents, please see the link below to access our CCPA Privacy Notice. CCPA Privacy Notice for California Residents ******************************* Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question - that choose to submit a resume or client information to our career page or to any employee of Fulgent - will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.
    $80k-131k yearly est. 17d ago
  • Research Scientist

    Tpirc

    Principal research scientist job in Long Beach, CA

    Job Description Job Title: Research Scientist Focus: Protein Biochemistry & Epitope Discovery Reports To: Director of Research Job purpose: The Research Scientist will support our growing program in Food allergen epitope discovery and cross-reactivity research. The role bridges protein chemistry, immunology, and mass spectrometry, with a focus on characterizing allergenic proteins and mapping epitope-level interactions that influence immune tolerance and cross-reactivity. The scientist will contribute directly to translational research aimed at improving diagnostic precision and guiding biosimilar protein immunotherapy strategies. Duties and Responsibilities: Protein Extraction & Purification Perform defatting, extraction, and purification of proteins from complex biological or food-based materials. Operate and maintain High Performance Liquid Chromatography (HPLC) and related chromatography systems for protein fractionation and isolation. Assess protein purity and composition using SDS-PAGE, Western blot, and quantitative spectrophotometric analysis. Immunoassays & Binding Studies Design and execute ELISA-based binding and inhibition assays using patient or pooled allergic sera to evaluate IgE binding, cross-reactivity, and blocking capacity. Conduct avidity or competitive binding assays to characterize antibody affinity and specificity. Collaborate with the immunology team to translate biochemical findings into clinical and diagnostic relevance. Epitope Identification & Data Integration Prepare purified fractions for LC-MS/MS analysis and perform downstream bioinformatic peptide analysis to identify candidate epitopes. Integrate mass spectrometry, immunoassay, and structural modeling data to define clinically meaningful epitope patterns. Contribute to the design of new diagnostic assays and translational immunotherapy platforms based on identified protein domains. Collaboration & Communication Partner with cross-disciplinary teams including immunologists, data scientists, and clinicians. Maintain detailed experimental records, conduct data analysis, and contribute to publications, reports, grant applications, and conference presentations. Qualifications: PhD in Biochemistry, Molecular Biology, Immunology, Food Science, or a related field. Proven hands-on experience in protein purification and chromatographic separation (HPLC required). Strong background in binding and inhibition assay development (ELISA, competitive binding, or similar platforms). Experience interpreting and correlating mass spectrometry proteomic data Excellent technical writing, organizational, and collaborative skills. Preferred experience: Prior research involving food allergens, seed storage proteins, or other clinically relevant immunogenic proteins. Familiarity with IgE/IgG binding kinetics, cross-reactivity mechanisms, and allergen structural biology. Understanding of biosimilar protein immunotherapy principles and translational allergy research. Physical requirements: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to talk or hear. The employee frequently is required to stand; walk; use hands to finger, handle or feel; and reach with hands and arms. The employee is required to walk between multiple office locations that include the use of stairs (elevator is only available in some instances). This position requires the ability to occasionally lift office products and supplies, up to 20 pounds. Direct reports: N/A The company provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, marital status, veteran status, or any other consideration made unlawful by federal, state, or local laws. The company is committed to providing reasonable accommodation for qualified applicants, and employees with disabilities to ensure they enjoy equal access to all employment opportunities and benefits of employment as required by the Americans with Disabilities Act.
    $90k-151k yearly est. 18d ago
  • Research Scientist, Self-Replication

    Galactic Resource Advancement Mechanism Technologies Corporation

    Principal research scientist job in El Segundo, CA

    Job Description The Mission At GRAM, we believe the next great leap for humanity will be physical, not digital. What AGI is to bits, Self-Replication (SR) is to atoms. As an SR research and deployment company, our mission is to make humanity galactic by enabling physical exponential growth. To achieve this, we are conducting foundational research across general-purpose robotics, artificial intelligence, biology, and materials science to enable SR within our lifetimes. Our first step is to challenge the consensus that robots should look like us. We believe true progress comes from optimizing for function over form. We are creating a new embodiment for intelligence, designed from first principles to build the future physical economy, on and off-world. The Role Self-Replication is to the physical world what AGI is to the digital: a foundational, recursively improving capability with a vast and undefined ceiling. The person in this role will not merely apply known principles; they are responsible for discovering the fundamental laws and architecting the core intelligence of this new paradigm. This is an opportunity to define a field. Your work will be to answer one of the most profound questions in technology: how does a system build a system? The scope of this question is not limited to a single machine. It encompasses the entire chain of logistics, energy, manipulation, and assembly required for a technological ecosystem to grow. Your research will form the bedrock upon which our engineering teams build the future, shaping not just our products, but the very economic and industrial logic of our expansion into the solar system. This role requires a unique combination of scientific rigor, strategic foresight, and architectural vision. We are looking for a singular mind to lead this charge, establishing a research program from the ground up with the resources and mandate to pursue a multi-decade mission that will alter the course of human history. Key Responsibilities: Architect the foundational thesis for Self-Replication at GRAM, creating the intellectual framework that distinguishes our pragmatic, systems-based approach from all other efforts in the field. Develop the physical genome for all GRAM hardware. This involves establishing the core design principles that ensure our systems are intrinsically capable of being built, assembled, and maintained by other machines. Lead the conceptual design of "GAIA," the governing intelligence for planetary scale industrial automation, resource allocation, and the expression of collective human ambition. Act as a key strategic partner to the CEO, translating the company's grand vision into an actionable, multi-decade technical roadmap. Serve as the company's foremost thought leader on SR, acting as a magnet for attracting a world class team of scientists and engineers. About You Your mind operates on two levels simultaneously. On one, you are a physicist and theorist, comfortable with the highest levels of abstraction in information theory, economics, and complex systems. On the other, you are a pragmatic systems thinker with an unnerving intuition for how the real world industrial machine, with all its constraints, inefficiencies, and gritty complexities, actually works. You are driven not just by the pursuit of knowledge, but by the desire to build the systems that will reshape civilization. You are not just a researcher; you are the architect of a new economic and industrial paradigm. Basic Qualifications: A PhD in Physics, Computer Science, Systems Engineering, or a related discipline. A history of conceiving and driving forward large scale, open ended, and audacious projects, either in academia or industry. A demonstrable, deep understanding of complex systems, whether industrial, economic, or biological. The ability to create and communicate a compelling, long term technical vision. Preferred Qualifications: A body of work (publications, patents, or a portfolio of private projects) that points to a sustained intellectual obsession with large scale systems, automation, or the future of industrial technology. Experience in a strategic role that required bridging the gap between frontier R&D and practical engineering or business constraints. The ability to develop and defend a multi decade technical roadmap to investors, partners, and employees. A fundamental, first principles approach to problem solving that is not constrained by existing disciplines or dogma. Location This is an on-site role at our research lab in El Segundo, California. We offer significant relocation assistance for exceptional candidates. Interview Process After submitting your application, we review your portfolio and any exceptional work you've shipped. If your application demonstrates the caliber we seek, you'll enter our interview process, which is designed for speed and substance. We aim to complete it within one week from start to finish. Compensation Your total compensation reflects both the significance of early-stage equity and competitive market rates. The following is the general framework for all roles at GRAM. Company-Wide Base Salary Range: $75,000 - $300,000 USD, calibrated to your impact potential Equity: Substantial ownership stake befitting founding team members Benefits: Health, dental, and vision coverage; all meals are paid for; relocation assistance GRAM is an equal opportunity employer. We evaluate solely on capability and drive. Why Join? We are an early, focused team of scientists and engineers building the system that builds itself. GRAM is funded by leading investors and long-term visionaries. We operate without bureaucracy. Ownership and leadership flow to those who demonstrate exceptional capability, and every team member works directly on our core technology. We are based in El Segundo, the heart of America's industrial future, focused on solving one of the most important problems of our time.
    $91k-152k yearly est. 28d ago
  • Research Scientist, Entomology

    Gram

    Principal research scientist job in El Segundo, CA

    The Mission At GRAM, we believe the next great leap for humanity will be physical, not digital. What AGI is to bits, Self-Replication (SR) is to atoms. As an SR research and deployment company, our mission is to make humanity galactic by enabling physical exponential growth. To achieve this, we are conducting foundational research across general-purpose robotics, artificial intelligence, biology, and materials science to enable SR within our lifetimes. Our first step is to challenge the consensus that robots should look like us. We believe true progress comes from optimizing for function over form. We are creating a new embodiment for intelligence, designed from first principles to build the future physical economy, on and off-world. The Role At GRAM, our engineering is built on a foundation of scientific discovery. This role is for the scientists who work at the frontier, creating the fundamental breakthroughs that will enable our future technology. You will be responsible for tackling high-risk, high-reward challenges, transforming nascent scientific principles into tangible, ownable advantages that redefine what is possible. We are not building traditional hexapods; we are building a new class of machine inspired by the most successful and diverse life forms on our planet. Our robot's design is guided by the elegant solutions insects have evolved for locomotion, manipulation, and social coordination. This role is for a scientist who can look at an ant colony and see a blueprint for a distributed factory, or see in a praying mantis the inspiration for a new kind of manipulator. Your work will form the bedrock upon which our engineering teams build the future. This is a chance to establish the intellectual and scientific foundation of a new field of robotics, with the resources and mandate to pursue your curiosity in service of an ambitious, long-term mission. Key Responsibilities: Act as the company's chief biological architect, guiding the design of our robots by providing deep, actionable insights from the field of entomology and biomechanics. Translate the complex principles of insect locomotion, manipulation, and multi-agent social structures into clear engineering specifications, kinematic models, and control strategies. Establish and curate a foundational "Bio-Inspired Design Library" that will serve as the creative and technical wellspring for our engineering teams for years to come. Work as a deeply embedded, multi-disciplinary partner, joining design reviews, simulation sessions, and hardware tests to ensure our machines are not just insect-like, but embody the core efficiencies of their biological counterparts. Identify and de-risk the most promising avenues of bio-inspiration, guiding the company's R&D roadmap toward the highest-impact biological solutions. About You You are a first-principles thinker who finds equal beauty in the emergent behavior of an ant colony and the elegance of a well-defined control system. You are driven by a deep curiosity about the natural world and a palpable passion for applying that knowledge to create new technology. You thrive in a high-agency environment where you can chart the course of your own research in service of a mission that will change the world. Basic Qualifications: A PhD in Entomology, Zoology, Biomechanics, or a related field of biology. A proven track record of significant, original research in your area of expertise. A history of successful and enthusiastic cross-disciplinary collaboration with engineering, physics, or computer science teams. An innate ability to communicate complex biological concepts with clarity and passion to non-biologists. Preferred Qualifications: A recognized global expert in a relevant sub-field, such as insect biomechanics, swarm intelligence, or invertebrate neurobiology. Direct experience working in a biorobotics lab, with a portfolio of projects where biological insights led to novel engineering outcomes. A "full-stack" scientific capability, from field/lab experimentation to data analysis, computational modeling, and the presentation of engineering-relevant insights. An inventive, entrepreneurial spirit and a desire to see your life's work manifested in machines that will travel to other worlds. Location This is an on-site role at our research lab in El Segundo, California. We offer significant relocation assistance for exceptional candidates. Interview Process After submitting your application, we review your portfolio and any exceptional work you've shipped. If your application demonstrates the caliber we seek, you'll enter our interview process, which is designed for speed and substance. We aim to complete it within one week from start to finish. Compensation Your total compensation reflects both the significance of early-stage equity and competitive market rates. The following is the general framework for all roles at GRAM. Company-Wide Base Salary Range: $75,000 - $300,000 USD, calibrated to your impact potential Equity: Substantial ownership stake befitting founding team members Benefits: Health, dental, and vision coverage; all meals are paid for; relocation assistance GRAM is an equal opportunity employer. We evaluate solely on capability and drive. Why Join? We are an early, focused team of scientists and engineers building the system that builds itself. GRAM is funded by leading investors and long-term visionaries. We operate without bureaucracy. Ownership and leadership flow to those who demonstrate exceptional capability, and every team member works directly on our core technology. We are based in El Segundo, the heart of America's industrial future, focused on solving one of the most important problems of our time.
    $91k-152k yearly est. Auto-Apply 60d+ ago
  • Associate Scientist

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Thousand Oaks, CA

    Ideal candidate will have a strong background in biochemistry and hands-on experience with protein purification and analytics, using various preparative and analytical chromatography techniques in a lab-based environment. Proficiency with lab software such as Unicorn, Chromeleon, or ChromeLab is preferred, along with familiarity with lab automation and high-throughput purification workflows. They should demonstrate strong troubleshooting skills, attention to detail, and robust data handling capabilities, as well as excellent communication skills suited to a fast-paced laboratory setting. Candidates must hold a bachelor's degree with at least 3 years of relevant experience or a master's degree with at least 1 year experience. This is a full-time, onsite position in Thousand Oaks, operating during standard business hours for a minimum duration of 1 year. Applicants without experience in protein purification or protein analytics will not be considered. **Preferred Qualifications:** + Experience with protein purification with expertise in a variety of chromatography techniques (affinity, ion-exchange, size-exclusion, etc.) and software (Unicorn, ChromLab) + Experience with protein analytical techniques (HPLC, MCE, etc.) and analysis software (Chromeleon, LabChip) + Experience with data management and/or analysis platform, software or tools is a plus + Ability to multi-task, work flexibly and efficiently in a cross-functional environment + Attention to detail; strong communication and interpersonal skills **Basic Qualifications:** + Masters degree OR + Bachelors degree and 2 years of experience OR + Associate's degree and 4 years of experience OR + High school diploma / GED and 6 years of experience **Must Have Skill Sets:** + Protein purification (affinity, IEX, SEC, etc.). + Protein analytics (HPLC, MCE, etc.). + Data management and handling. **Day to Day Responsibilities:** + Protein purification using various preparative protein chromatography techniques (affinity, ion-exchange, size-exclusion, etc.). + Protein analytics using various analytical techniques (HPLC, MCE, etc.). + Capture experimental data in LIMS/ELN systems. + Compile and analyze large dataset of protein purification and analytics results. + Summarize and present results and findings to work group and project teams. + Contribute to the development of new processes and methods. **About US Tech Solutions:** US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit *********************** . "US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran"
    $67k-101k yearly est. 21d ago
  • Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute

    Dev 4.2company rating

    Principal research scientist job in Lawndale, CA

    Company DescriptionJobs for Humanity is partnering with CEDARS-SINAI to build an inclusive and just employment ecosystem. Therefore, we prioritize individuals coming from the following communities: Refugee, Neurodivergent, Single Parent, Blind or Low Vision, Deaf or Hard of Hearing, Black, Hispanic, Asian, Military Veterans, the Elderly, the LGBTQ, and Justice Impacted individuals. This position is open to candidates who reside in and have the legal right to work in the country where the job is located. Company Name: CEDARS-SINAI Job Description Principal Investigator, Ivan Cokic, PhD, is looking for a Postdoctoral Scientist to join the Biomedical Imaging Research Institute! The Cedars-Sinai Biomedical Imaging Research Institute (BIRI) is an interdisciplinary research program established in 2010 to develop and apply state-of-the-art imaging technologies to today's most pressing translational research and clinical questions. Led by founding director Debiao Li, PhD, the program builds on Cedars-Sinai's clinical and research strefngths, with the ultimate goal of using novel medical imaging technology to improve the diagnosis, treatment and prevention of diseases. The BIRI team is dedicated to educating and training the next generation of the brightest imaging scientists and clinicians through our robust pre-/post-doctoral and visiting-scientist training programs. In addition, we have numerous research collaborations with leading imaging researchers. To learn more, please visit Biomedical Imaging Research Institute | Cedars-Sinai. In this role, the Postdoctoral Scientist will be expected to work independently under the direction of Dr. Cokic and in close cooperation, as well as consultation, with other research staff. This interdisciplinary preclinical project combines advanced cardiac imaging, cardiac (electro)physiology, cardioimmunology, cardiovascular pathology, and metabolomics. In addition, assisting with investigating clinical applications of novel magnetic resonance imaging (MRI) and positron emission tomography (PET) techniques for diagnosing, phenotyping and risk-stratifying subjects with MI. As a Postdoctoral Scientist, perform routine and complex laboratory procedures throughout the training period and may develop, adapt, and implement new research techniques and protocols. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the P.I. Analyzes, interprets, summarizes and compiles data. Operates and maintains equipment and instruments. Department-Specific Responsibilities: Handling of large animal (farm pigs, Yucatan minipigs, etc.) models of myocardial infarction (MI). Writing Institutional Animal Care & Use Committee (IACUC) protocols. Coordinating animal surgeries with team of designated research technologists. Designing and coordinating imaging experiments on BIRI's PET/MRI scanners with team of designated research technologists. Analysis of cardiac MRI and PET imaging data as well as histopathology and metabolomics data. Perform advanced data and statistical analysis and will communicate scientific findings in papers and conference presentations. Assist with database creation and management, supervision of undergraduate/graduate students. Education: Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization required. Experience and Skills: Highly motivated and works independently on research projects designed by a mentor (typically the PI) within the area of specialization. Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Highly motivated with a proven track of record of publications. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection and analysis. Knowledge of safety standards, operation, and maintenance of specialized equipment. Working Title: Postdoctoral Scientist - Cokic Lab - Biomedical Imaging Research Institute Department: BMS - BioMed Imaging Res Inst Business Entity: Cedars-Sinai Medical Center Job Category: Academic/Research Job Specialty: Postdoctoral Position Type: Full-time Shift Length: 8 hour shift Shift Type: Day Base Pay:$64,500.00 - $93,600.00
    $64.5k-93.6k yearly 60d+ ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Santa Clarita, CA?

The average principal research scientist in Santa Clarita, CA earns between $105,000 and $241,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Santa Clarita, CA

$159,000
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