Post job

Research scientist jobs in Bothell, WA

- 965 jobs
All
Research Scientist
Scientist
Associate Research Scientist
Senior Scientist
Research Associate
Research Internship
Research Scientist Lead
Clinical Scientist
Biological Scientist
Research Investigator
Associate Scientist
Senior Research Associate Scientist
  • Sr. Applied Scientist, Amazon AI at Work

    Amazon Development Center U.S., Inc. 4.7company rating

    Research scientist job in Seattle, WA

    We're at a defining moment in enterprise AI. While most companies are building thin wrappers around foundation models, we're tackling the fundamental challenges that will shape how organizations work with AI over the next decade. We're seeking a Senior Applied Scientist who will lead the technical vision and innovation that will define the future of work at Amazon. You'll be at the forefront of Amazon's AI innovation, working directly with technologies that will power the next generation of business operations, with visibility at the highest levels of AWS and Amazon's leadership team. What we're building doesn't exist yet anywhere-we're creating AI systems that fundamentally transform how enterprises operate. The scientific challenges we face represent genuine gaps in how organizations integrate AI into their operations, and we're approaching them with the resources and scale to build real solutions, not just prototypes. This role has real ambiguity-the productive kind where customer problems are clear but scientific solutions need to be invented. You'll have high autonomy to drive the scientific strategy and technical implementation in an early team. The scale of impact is enormous-you'll be developing scientific innovations that will fundamentally change how Amazon operates and become the foundation for how enterprises worldwide integrate AI into complex knowledge work. But what makes this unique is the timing and technical depth. You'll be solving problems that don't have established solutions, inventing new scientific approaches alongside delivering production-grade systems. If you want to tackle intrinsically hard scientific challenges that don't have obvious solutions, if you want to advance the state of the art in AI, if you want your work to matter at scale-let's talk. Key job responsibilities • Design and architect complex AI agent systems for business and product management workflows at scale • Define and lead research initiatives in human-AI collaboration frameworks across multiple teams • Drive end-to-end delivery of novel AI solutions from inception to production, ensuring system-level technical requirements are met • Lead technical discovery and innovation through rapid experimentation while maintaining high standards • Mentor junior scientists and influence adoption of scientific best practices across teams • Author technical documentation and research papers that advance the field of AI agents We're looking for someone who combines deep technical expertise with strong business acumen and thrives in ambiguous, fast-paced environments. You should be passionate about creating AI solutions that enhance human capabilities while maintaining high standards for responsible AI development. The ideal candidate will have deep expertise in machine learning and distributed systems, with a proven track record of delivering innovative AI solutions into production. A day in the life You take ownership of the long-term scientific vision, product roadmaps, and technologies, defining how they should evolve. You build consensus through thoughtful discussions with stakeholders, engineers, and scientist peers across multiple teams. You bring deep expertise to provide context for current and future technology choices and make strategic recommendations on modeling approaches and system architecture to achieve transformative business outcomes and user experiences. About the team Amazon AI at Work (AIW) is a strategic AWS Applied AI Solutions team pioneering the next generation of AI products, with direct visibility and engagement from senior leadership. Our team brings together top-tier product managers, engineers, and scientists who thrive on turning ambitious AI concepts into services. We operate at the forefront of innovation, embracing the challenges of undefined territory as we build entirely new solutions - starting with internal products that have the potential to evolve into external customer offerings. Diverse Experiences AWS values diverse experiences. Even if you do not meet all of the qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn't followed a traditional path, or includes alternative experiences, don't let it stop you from applying. Why AWS? Amazon Web Services (AWS) is the world's most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating - that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. Inclusive Team Culture Here at AWS, it's in our nature to learn and be curious. Our employee-led affinity groups foster a culture of inclusion that empower us to be proud of our differences. Ongoing events and learning experiences, including our Conversations on Race and Ethnicity (CORE) and AmazeCon (gender diversity) conferences, inspire us to never stop embracing our uniqueness. Mentorship & Career Growth We're continuously raising our performance bar as we strive to become Earth's Best Employer. That's why you'll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional. Work/Life Balance We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why we strive for flexibility as part of our working culture. When we feel supported in the workplace and at home, there's nothing we can't achieve in the cloud. BASIC QUALIFICATIONS- 3+ years of building machine learning models for business application experience - PhD, or Master's degree and 6+ years of applied research experience - Experience programming in Java, C++, Python or related language - Experience with neural deep learning methods and machine learning PREFERRED QUALIFICATIONS- Experience in building machine learning models for business application - Strong background in human-AI interaction systems Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************** This position will remain posted until filled. Applicants should apply via our internal or external career site.
    $150.4k-260k yearly 2d ago
  • Sr. Applied Scientist, AWS Just-Walk-Out Science Team

    Amazon.com Services LLC 4.7company rating

    Research scientist job in Seattle, WA

    As part of the AWS Solutions organization, we have a vision to provide business applications, leveraging Amazon's unique experience and expertise, that are used by millions of companies worldwide to manage day-to-day operations. We will accomplish this by accelerating our customers' businesses through delivery of intuitive and differentiated technology solutions that solve enduring business challenges. We blend vision with curiosity and Amazon's real-world experience to build opinionated, turnkey solutions. Where customers prefer to buy over build, we become their trusted partner with solutions that are no-brainers to buy and easy to use. The Team Just Walk Out (JWO) is a new kind of store with no lines and no checkout-you just grab and go! Customers simply use the Amazon Go app to enter the store, take what they want from our selection of fresh, delicious meals and grocery essentials, and go! Our checkout-free shopping experience is made possible by our Just Walk Out Technology, which automatically detects when products are taken from or returned to the shelves and keeps track of them in a virtual cart. When you're done shopping, you can just leave the store. Shortly after, we'll charge your account and send you a receipt. Check it out at amazon.com/go. Designed and custom-built by Amazonians, our Just Walk Out Technology uses a variety of technologies including computer vision, sensor fusion, and advanced machine learning. Innovation is part of our DNA! Our goal is to be Earths' most customer centric company and we are just getting started. We need people who want to join an ambitious program that continues to push the state of the art in computer vision, machine learning, distributed systems and hardware design. Key job responsibilities Everyone on the team needs to be entrepreneurial, wear many hats and work in a highly collaborative environment that's more startup than big company. We'll need to tackle problems that span a variety of domains: computer vision, image recognition, machine learning, real-time and distributed systems. As a Sr. Applied Scientist, you will help solve a variety of technical challenges and mentor other scientists. You will be the thought leader of the team. You will tackle challenging, novel situations every day and given the size of this initiative, you'll have the opportunity to work with multiple technical teams at Amazon in different locations. You should be comfortable with a degree of ambiguity that's higher than most projects and relish the idea of solving problems that, frankly, haven't been solved at scale before - anywhere. Along the way, we guarantee that you'll learn a ton, have fun and make a positive impact on millions of people. A key focus of this role will be developing and implementing advanced visual reasoning systems that can understand complex spatial relationships and object interactions in real-time. You'll work on designing autonomous AI agents that can make intelligent decisions based on visual inputs, understand customer behavior patterns, and adapt to dynamic retail environments. This includes developing systems that can perform complex scene understanding, reason about object permanence, and predict customer intentions through visual cues. About the team AWS Solutions As part of the AWS solutions organization, we have a vision to provide business applications, leveraging Amazon's unique experience and expertise, that are used by millions of companies worldwide to manage day-to-day operations. We will accomplish this by accelerating our customers' businesses through delivery of intuitive and differentiated technology solutions that solve enduring business challenges. we blend vision with curiosity and Amazon's real-world experience to build opinionated, turnkey solutions. Where customers prefer to buy over build, we become their trusted partner with solutions that are no-brainers to buy and easy to use. About AWS Diverse Experiences AWS values diverse experiences. Even if you do not meet all of the preferred qualifications and skills listed in the job description, we encourage candidates to apply. If your career is just starting, hasn't followed a traditional path, or includes alternative experiences, don't let it stop you from applying. Why AWS? Amazon Web Services (AWS) is the world's most comprehensive and broadly adopted cloud platform. We pioneered cloud computing and never stopped innovating - that's why customers from the most successful startups to Global 500 companies trust our robust suite of products and services to power their businesses. Inclusive Team Culture AWS values curiosity and connection. Our employee-led and company-sponsored affinity groups promote inclusion and empower our people to take pride in what makes us unique. Our inclusion events foster stronger, more collaborative teams. Our continual innovation is fueled by the bold ideas, fresh perspectives, and passionate voices our teams bring to everything we do. Mentorship & Career Growth We're continuously raising our performance bar as we strive to become Earth's Best Employer. That's why you'll find endless knowledge-sharing, mentorship and other career-advancing resources here to help you develop into a better-rounded professional. Work/Life Balance We value work-life harmony. Achieving success at work should never come at the expense of sacrifices at home, which is why we strive for flexibility as part of our working culture. When we feel supported in the workplace and at home, there's nothing we can't achieve. BASIC QUALIFICATIONS- 3+ years of building machine learning models for business application experience - PhD, or Master's degree and 6+ years of applied research experience - Experience programming in Java, C++, Python or related language - Experience with neural deep learning methods and machine learning PREFERRED QUALIFICATIONS- Experience in visual design expertise with ability to produce fresh, simple, elegant and exceedingly usable layouts and interactions and iconography - Demonstrated experience in AI agent architecture design, including decision-making frameworks and behavioral modeling; - Experience with advanced computer vision techniques including scene graph generation, visual relationship detection, and spatial reasoning - Knowledge of modern visual-language models and multi-modal AI systems - Experience implementing reinforcement learning for autonomous agent behavior - Experience in professional software development Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************** This position will remain posted until filled. Applicants should apply via our internal or external career site.
    $150.4k-260k yearly 5d ago
  • Machine Learning Scientist III - Growth Marketing (Production GenAI & Agentic Multimodal Workflows)

    Expedia Group 4.7company rating

    Research scientist job in Seattle, WA

    Introduction to the team We create and deliver an aligned, dedicated marketing strategy to fuel each Expedia Group brand's success. Since our travelers interact with us through our brands, we have a brand focus in our marketing, while leveraging the scale and efficiency we've built in functional expertise. At Expedia Group, our Growth Marketing team is redefining how data-driven marketing meets AI-powered, agentic automation. We drive performance through best-in-class, scalable machine learning, deploying production-ready multimodal LLMs, GenAI, and agentic NLP architectures. Our agentic systems power everything from personalized travel discovery to real-time, cross-platform campaign execution at massive scale. Explore “Trip Matching” on Instagram for a glimpse into our production chatbot transforming inspiring reels and posts into hotel recommendation. As an ML Scientist III, your mission is to engineer, and scale production AI workflows, agents, and multimodal LLM pipelines, leveraging both in-house and third-party systems. You'll develop agentic solutions with advanced orchestration tools like LangGraph, Langfuse, RAG, and the latest frameworks, owning end-to-end delivery and optimizations for inference and GenAI systems. In this role, you will: Develop and deploy complex agentic and multimodal AI workflows at production scale, architecting memory-enabled, context-aware agents that drive dynamic automation, personalization, real-time monitoring and content generation. Design and orchestrate advanced LLM and RAG-driven agent solutions using modular frameworks including LangGraph, Langfuse, CrewAI, AutoGen, and other emerging agentic orchestration tools-enabling adaptive, stateful, and highly interactive workflow graphs. Integrate and optimize complete multimodal GenAI pipelines: text-to-image, image-to-video, text-to-video, and text-to-voice, leveraging and extending in-house and third party models. Fine-tune (parameter-efficient tuning, LoRA, QLoRA, etc.), and evaluate (perplexity, accuracy, creativity metrics) both open-source (Llama, MPT, Phi-4, etc.) and commercial LLMs (OpenAI GPT-4, Gemini, Claude). Pioneer LLM-based simulation & evaluation environments (e.g., LLM-as-a-Judge): Leverage the latest LLMs, multi-agent systems, and generative tools to simulate user behavior, accelerate experimental cycles, and rigorously evaluate new features or workflows in both synthetic and prod online shopping and travel environments. Simulate A/B testing via LLM simulations: Build A/B test agents capable of simulating user engagement, behavioral outcomes, and marketing scenarios to complement and replace large-scale online testing-enabling rapid iteration, robust pre-deployment validation, and deeper insight into agentic/LLM-driven feature impact. Continuously adopt and iterate on the latest frameworks, staying current with state-of-the-art in agentic orchestration, memory models, multimodal GenAI, LLM pipelines, and LLM operation (RAG, memory, tracing, evaluation). Collaborate deeply with engineering, marketing, and product teams to translate evolving business objectives into scalable and observable AI-driven solutions. Experience and qualifications: Minimum 7+ years experience delivering robust, scalable AI/GenAI solutions at enterprise scale with a Bachelors degree (4-5+ year of relevant experience with a Masters/PhD in CS, EE, Stats) Agentic frameworks experience working with platforms such as LangGraph, Langfuse, RAG, CrewAI, AutoGen, and comparable agent workflow frameworks Ability to design complex agent graphs with memory, tool calling, and multi-step reasoning Multimodal and agentic AI experience in both commercial and open-source models (VLMs, CLIP, Phi-4, DINO, etc), advanced LLM pipeline design, and shipping both inference and generative AI features to users Hands-on experience in fundamental neural network models (CNN, Transformers, BERT, VAEs, Multimodals etc) Proven expertise in architecting persistent, hybrid, and context-managed memory for agentic workflows Strong in Python (PyTorch, HuggingFace, etc.), MLOps, distributed systems (PySpark, Databricks, Airflow), and scalable API engineering Deep experience with tracing, logging, and observability stacks (Langfuse, PromptLayer, Weights & Biases, etc.), including prompt monitoring and model evaluation in live production Ability to translate complex technical systems into actionable solutions for cross-functional teams, leveraging Multimodal LLMs and Gen AI models
    $100k-134k yearly est. 4d ago
  • Applied Perception Scientist

    Crystal Equation Corporation 4.2company rating

    Research scientist job in Redmond, WA

    Applied Perception Scientist IV Onsite - Redmond, WA Our client is a leading research organization of world-class researchers, developers, and engineers, who collaborate to actively create a future where virtual and augmented reality become as indispensable as today's smartphones and personal computers. The mission of the Virtual Reality Research Audio team is to engineer augmented audio that redefines human hearing capabilities. This will allow us to connect people by facilitating conversation in even the most challenging auditory environment. We are seeking a contract applied research scientist specializing in the perception of tonal languages. This role is an integral part of our team, contributing to our research and development efforts. The ideal candidate will help us explore and understand individualized audio quality preferences and experiences, enabling us to tailor our technologies to meet unique user needs. Responsibilities: Oversee and drive research projects on speech quality, statistically analyze results and report findings. Monitor problems, facilitate resolution, and proactively keep projects on track. Implement and conduct pilot listening tests and other perceptual experiences. Regularly report on project progress, dependencies and risks to stakeholders. Support research scientists and engineers within the team. Manage procurement projects for equipment and vendor services. Willingness to "roll up sleeves" and take on operational tasks in support of the team's goals. Minimum Qualifications: Interpersonal and communication skills, with strong attention to detail. Proactive with ability to execute on multiple projects simultaneously. Strong organizational and time management skills. Track record of communicating research on speech perception, hearing sciences or auditory perception in an academic or industrial setting. Experience with data collection with human participants. Experience working in a fast-paced research and/or product development environment. Experience with scientific programming languages such as Matlab, Python, C++, or R. Master's degree or equivalent experience in Computational Neuroscience, Cognitive Science, Electrical Engineering, Perception, Experimental Psychology, Audio Engineering, Acoustics, Computer Science, Computer Engineering, Biomedical Engineering, Computational Audiology or a related field. Preferred Qualifications: Experience with tonal languages. PhD degree or equivalent experience. Experience with AI generative speech. Experience with modeling audio quality. Pay range is $71 - $76 per hour with full benefits available, including paid time off, medical/dental/vision/life insurance, 401K, parental leave, and more. Our compensation reflects the cost of labor across several US geographic markets. Pay is based on several factors including market location and may vary depending on job-related knowledge, skills, and experience. THE PROMISES WE MAKE: At Crystal Equation, we empower people and advance technology initiatives by building trust. Your recruiter will prep you for the interview, obtain feedback, guide you through any necessary paperwork and provide everything you need for a successful start. We will serve to empower you along the way and provide the path for your professional journey. For more information regarding our Privacy Policy, please visit crystalequation.com/privacy.
    $71-76 hourly 4d ago
  • Bench Scientist

    Tech Observer

    Research scientist job in Bothell, WA

    Contract - 6 Months contract with a possibility of extension The In Situ Biology team is seeking a motivated associate scientist contractor to assist a team of scientists performing spatial biology experiments aimed at understanding targets for antibody-based therapeutics. The successful candidate will have experience in core histology methodologies, including processing, embedding, and sectioning. The ideal candidate will be energetic and enthusiastic about lab work and flexible in working with different investigators on various projects. Responsibilities Process samples for downstream histological analysis. Perform routine histology lab maintenance. Perform immunohistochemistry experiments using autostainers. Maintain and catalog a biospecimen repository. Utilize a LIMS system for documenting experiments. Qualifications 1-2+ years' experience working in a laboratory. BS or BA in a biological science. Experience with histopathology techniques. Experience with sectioning is a plus; preference given to Histology Technicians (HTs). Ability to work collaboratively in a cross-functional research environment. Highly organized with the ability to multitask. Quick learner with a willingness to learn new skills and technologies. Excellent teamworking and communication skills, and a proactive attitude.
    $69k-110k yearly est. 4d ago
  • Bench Scientist

    Pharmaceutical Company 3.9company rating

    Research scientist job in Bothell, WA

    The In Situ Biology team is seeking a motivated associate scientist contractor to assist a team of scientists performing spatial biology experiments aimed at understanding targets for antibody-based therapeutics. The successful candidate will have experience in core histology methodologies, including processing, embedding, and sectioning. The ideal candidate will be energetic and enthusiastic about lab work and flexible in working with different investigators on various projects. Responsibilities • Process samples for downstream histological analysis. • Perform routine histology lab maintenance. • Perform immunohistochemistry experiments using autostainers. • Maintain and catalog a biospecimen repository. • Utilize a LIMS system for documenting experiments. Qualifications • 1-2+ years' experience working in a laboratory. • BS or BA in in a biological science. • Experience with histopathology techniques. • Experience with sectioning a plus, preference given to Histology Technicians (HTs). • Ability to work collaboratively in a cross-functional research environment. • Highly organized with the ability to multitask. • Quick learner with willingness to learn new skills and technologies. • Excellent teamworking and communication skills and a proactive attitude.
    $88k-114k yearly est. 1d ago
  • AI Speech Research Intern

    Centific

    Research scientist job in Redmond, WA

    PhD Research Intern - Speech AI Centific AI Research Fulltime - 40 hours per week Centific AI Research seeks a PhD Research Intern to design and evaluate speech‑first models, with a focus on Spoken Language Models (SLMs) that reason over audio and interact conversationally. You'll move ideas from prototype to practical demos, working with scientists and engineers to deliver measurable impact. Scope of Work End‑to‑end speech dialogue systems (speech‑in/speech‑out) and speech‑aware LLMs. Alignment between speech encoders and text backbones via lightweight adapters. Efficient speech tokenization and temporal compression suitable for long‑form audio. Reliable evaluation across recognition, understanding, and generation tasks-including robustness and safety. Latency‑aware inference for streaming and real‑time user experiences. Example Projects Prototype a conversational SLM using an SSL speech encoder and a compact adapter on an existing LLM; compare against strong baselines. Create a data recipe that blends conversational speech with instruction‑following corpora; run targeted ablations and report findings. Build an evaluation harness that covers ASR/ST/SLU and speech QA, including streaming metrics (latency, stability, endpointing). Ship a minimal demo with streaming inference and logging; document setup, metrics, and reliability checks. Author a crisp internal write‑up: goals, design choices, results, and next steps for productionization. Minimum Qualifications PhD candidate in CS/EE (or related) with research in speech, audio ML, or multimodal LMs. Fluency in Python and PyTorch, with hands‑on GPU training; familiarity with torchaudio or librosa. Working knowledge of modern sequence models (Transformers or SSMs) and training best practices. Depth in at least one area: (a) discrete speech tokens/temporal compression, (b) modality alignment to LLMs via adapters, or (c) post‑training/instruction tuning for speech tasks. Strong experimentation habits: clean code, ablations, reproducibility, and clear reporting. Preferred Qualifications Experience with speech generation (neural codecs/vocoders) or hybrid text+speech decoding. Background in multilingual or code‑switching speech and domain adaptation. Hands‑on work evaluating safety, bias, hallucination, or spoofing risks in speech systems. Distributed training/serving (FSDP/DeepSpeed), and experience with ESPnet, SpeechBrain, or NVIDIA NeMo. Tech Stack PyTorch, CUDA, torchaudio/librosa; experiment tracking (e.g., Weights & Biases). LLM backbones with lightweight adapters; neural audio codecs and vocoders as needed. FastAPI/gRPC for services; ONNX/TensorRT and quantization for efficient inference. What We Offer Competitive stipend and hands-on projects with measurable real-world impact. Mentorship from applied scientists and engineers; opportunities to publish and present. Access to modern GPU infrastructure and a supportive environment for fast, responsible experimentation. Flexible location and schedule options, subject to team needs. Benefits: Comprehensive healthcare, dental, and vision coverage 401k plan Paid time off (PTO) And more! Learn more about us at centific.com. Centific is an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, ancestry, citizenship status, age, mental or physical disability, medical condition, sex (including pregnancy), gender identity or expression, sexual orientation, marital status, familial status, veteran status, or any other characteristic protected by applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
    $44k-70k yearly est. 4d ago
  • Oncology Early Stage Clinical Scientist (Director, Non-MD)

    Pfizer 4.5company rating

    Research scientist job in Bothell, WA

    You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team This position does not require you to be medical qualified. Demonstrates diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make ********************** accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical
    $97k-122k yearly est. 4d ago
  • Scientist/ Research Associate - AI Protein Design

    Systimmune, Inc.

    Research scientist job in Redmond, WA

    SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are looking for a creative and motivated individual to execute and improve our Computational Protein Design pipeline using data-driven approaches to augment our first-in-class multi-specific biological programs. The ideal candidate will have experience applying computational methods to design novel peptides and proteins, with expertise in structural modeling, prediction, and optimization. Responsibilities: * Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach * Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms * Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process * Analyze, interpret, document, and present data to the scientific and leadership team * Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision Qualifications: * PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field * 8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required * Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger) * Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET) * Proven contribution to therapeutic antibody development and selection is desirable; design and validation of novel biologically relevant antibodies are highly desirable Compensation and Benefits: The expected base salary range for this position is $80,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
    $56k-89k yearly est. 21d ago
  • Scientist/ Research Associate - AI Protein Design

    Systimmune

    Research scientist job in Redmond, WA

    SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are looking for a creative and motivated individual to execute and improve our Computational Protein Design pipeline using data-driven approaches to augment our first-in-class multi-specific biological programs. The ideal candidate will have experience applying computational methods to design novel peptides and proteins, with expertise in structural modeling, prediction, and optimization. Responsibilities: Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process Analyze, interpret, document, and present data to the scientific and leadership team Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision Qualifications: PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field 8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger) Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET) Proven contribution to therapeutic antibody development and selection is desirable; design and validation of novel biologically relevant antibodies are highly desirable Compensation and Benefits: The expected base salary range for this position is $80,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
    $56k-89k yearly est. Auto-Apply 60d+ ago
  • Associate Research Scientist

    R&D Partners

    Research scientist job in Seattle, WA

    R&D Partners is seeking to hire an Associate Research Scientist in Seattle, WA. Your main responsibilities as an Associate Research Scientist: Assist in developments of fit-for-purpose potency and/or biological characterization assays for both early- or late-stage programs. Works under minimal supervision for routine activities, such as experimental execution based on established protocols, data review and analysis. Organize findings for effective and timely communication of data, draw appropriate conclusions and design next steps. Maintain notebooks with detailed and timely documentation of protocols, study designs and results. Responsible for setting up in vitro functional assays to measure T cell function. What we are looking for in an Associate Research Scientist: B.S. in biological science, immunology or related discipline with at least 2 years of relevant work experience or M.S. with minimum of 1 year of relevant work experience in T cell biology Direct cell culture experience is required. Technical experience with cell-based assay development is preferred. Knowledge of cGxP requirements preferred. Works predominantly within established procedures but is capable of recognizing potential problems and recommend/develop appropriate solutions.. Why Choose R&D Partners? As an employee, you have access to a comprehensive benefits package including: Medical insurance PPO, HMO & HSA Dental & Vision insurance 401k plan Employee Assistance Program Long-term disability Weekly payroll Expense reimbursement Online timecard approval Pay Scale: $56,343 $70,442 ( Dependent on Experience) R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal-opportunity employer.
    $56.3k-70.4k yearly 60d+ ago
  • Applied Scientist, Generative AI/ML

    Adobe Systems Incorporated 4.8company rating

    Research scientist job in Seattle, WA

    Our Company Changing the world through digital experiences is what Adobe's all about. We give everyone-from emerging artists to global brands-everything they need to design and deliver exceptional digital experiences! We're passionate about empowering people to create beautiful and powerful images, videos, and apps, and transform how companies interact with customers across every screen. We're on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We realize that new ideas can come from everywhere in the organization, and we know the next big idea could be yours! The Opportunity Adobe is seeking to add Applied Scientists in Generative AI to our world-class AI Platform team. We are specifically looking for scientists with expertise in preparing data, training, fine-tuning and adapting large foundation models across all modalities: images, video, 3D, LLMs and cross-modal setups. We welcome outstanding candidates in all related technical fields, such as Machine Learning, Deep Learning, Computer Vision, and Natural Language Processing. The related applications include image/video/3D generation, editing, and understanding, conditioned on controls stemming from large language models, or other innovative interactions tailored for creative workflows, and multimodal priors. What You'll Do * Conduct pioneering research and development in Generative AI for visual (image/video/3D), audio, and multi-modal outputs. * Develop and deploy novel generative AI technologies to existing and new Adobe Products. * Research and develop novel large-scale foundation models with deep reasoning and world-building capabilities. * Collaborate with world-class researchers and ML engineers to bring research ideas to creative workflows used by millions. * Publish and present your work in world-class scientific venues in CV/AI/ML/CG fields Required Qualifications * Ph.D. in Computer Science, CV/AI/ML/CG or related fields and 1+ years professional experience. * Research or industry experience in training Generative AI models (pre-training and/or post-training) in at least one of the following modalities: image, video, 3D, or audio. * Expertise in large-scale model training and optimization, including data curation, distributed training, and memory-efficient techniques. * Experience with post-training techniques such as fine-tuning, alignment or distillation. * Proficiency with modern deep learning frameworks (e.g., PyTorch) and experience scaling models on GPU/TPU clusters. * Excellent communication skills and a strong great teammate What You'll Bring * Experience on large-scale generative model training * Experience on synthetic data generation * Experience of working with large-scale datasets * Experience of working with product teams on technology transfers #FireflyGenAI Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The U.S. pay range for this position is $142,700 -- $257,600 annually. Pay within this range varies by work location and may also depend on job-related knowledge, skills, and experience. Your recruiter can share more about the specific salary range for the job location during the hiring process. At Adobe, for sales roles starting salaries are expressed as total target compensation (TTC = base + commission), and short-term incentives are in the form of sales commission plans. Non-sales roles starting salaries are expressed as base salary and short-term incentives are in the form of the Annual Incentive Plan (AIP). In addition, certain roles may be eligible for long-term incentives in the form of a new hire equity award. State-Specific Notices: California: Fair Chance Ordinances Adobe will consider qualified applicants with arrest or conviction records for employment in accordance with state and local laws and "fair chance" ordinances. Colorado: Application Window Notice There is no deadline to apply to this job posting because Adobe accepts applications for this role on an ongoing basis. The posting will remain open based on hiring needs and position availability. Massachusetts: Massachusetts Legal Notice It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Adobe is proud to be an Equal Employment Opportunity employer. We do not discriminate based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Learn more. Adobe aims to make Adobe.com accessible to any and all users. If you have a disability or special need that requires accommodation to navigate our website or complete the application process, email accommodations@adobe.com or call **************.
    $142.7k-257.6k yearly 60d+ ago
  • Clinical Research Investigator (MD/DO)

    DM Clinical Research

    Research scientist job in Seattle, WA

    Clinical Research Investigator DM Clinical Research, the largest privately-owned research management organization in the Houston area and one of the top 50 in the country, is looking for an Investigator for our sites in Seattle, WA. This individual will conduct all clinical trials (studies) according to ICH, GCP, local regulations, study protocols, and company processes. Responsibilities Ensures the medical well-being and safety of the participants through the safe performance and execution of the studies. Assists in maintaining clinical oversight and quality on the studies registered on and delivers on study targets, thereby contributing to the commercial success of the site. Reviews enrollment progress, pre-screening and screening success rates, screen failure rates, safety, and retention of participants. Interprets protocols and IB and participates in initiatives to strategize for patient recruitment. Carries out clinical evaluation and assessment of participants to ensure eligible participants are enrolled onto studies. Ensures and protects the welfare and safety of participants through ethical conduct. Fulfills and comply with all medical duties as per protocol, SOP/COP and ICH GCP and local regulations. Exercises meticulous attention to detail in documentation and patient care. Requirements Medical License (MD, DO) At least 2 years of experience as a Clinical Research Investigator. Spanish Bilingual a plus.
    $67k-114k yearly est. 60d+ ago
  • Research Associate - Chem

    Altpep Corp

    Research scientist job in Seattle, WA

    AltPep Corporation is a biomedical company based along Seattle's Lake Union developing groundbreaking disease-modifying treatments and detection tools for amyloid diseases by targeting a novel early molecular trigger: alpha sheet oligomers. Our lead programs focus on Alzheimers and Parkinsons diseases, with other amyloid diseases on the horizon. AltPeps goal is to change the course of these debilitating diseases that affect over a billion people around the globe. AltPep draws its origins to Dr. Valerie Daggett's lab at the University of Washington's Bioengineering Department. We are looking for additional team members to join us at our state-of-the-art, headquarters located on the Eastside of Lake Union in Seattle. About this Role We are seeking a meticulous and dynamic Research Associate to join our team. You will be responsible for conducting and supporting laboratory research, including peptide synthesis, characterization (spectroscopy, biophysical, etc.), formulation activities, bioanalytical (pharmacokinetics) experiments, and stability studies, while ensuring the highest standards of quality and precision. Your contributions will be critical to the success of our research and development efforts, and you will have opportunities to work both independently and collaboratively within our innovative team. What Youll Do: Characterize peptides by UHPLC, mass spectrometry, circular dichroism, etc. Engage in chemical synthesis and peptide modifications to meet research and development objectives. Operate both manual and automated solid-phase peptide synthesis systems. Conduct (prep- and semi-prep) HPLC purification of peptides. Support novel Drug Product formulation development Support bioanalytical experiments and stability studies Troubleshoot and maintain instrumentation to ensure smooth laboratory operations. Maintain rigorous quality of experimental details outlined in Standard Operating Procedures (SOPs). Document research findings meticulously in lab books and records. Work both independently and collaboratively within an innovative team to achieve project goals. Prioritize and organize workflow to manage multiple tasks efficiently. Maintain a clean and orderly laboratory environment. Analyze and interpret data and generate reports Regularly communicate results, in written form and oral presentations, to the rest of the team and occasionally to senior management and in All-Company meetings. What You Bring: Must Haves: Bachelor's degree in chemistry, chemical engineering, biochemistry, bioengineering, or a related field. Experience in instrumental analysis using HPLC, UHPLC, and LC-MS. Ability to conduct quantitative analysis and apply quality control criteria effectively. Meticulous record-keeping abilities and attention to detail. Flexibility to adapt to a fast-paced and dynamic work environment and responsiveness to quick changes in tasks/priorities. Ability to learn rapidly and implement new laboratory techniques as needed Strong organizational skills to manage multiple tasks and prioritize workflow. What Will Separate You From the Rest: 2+ years of post-graduate experience in a relevant field, with previous biotech experience being a plus. Hands-on experience with solid-phase peptide synthesis and HPLC purification. Experience with productivity and scientific software, including ChemDraw /Marvinsketch Familiarity with PubMed and other information sources for pharmaceuticals. Ability to work independently while also valuing team collaboration. Knowledge of Quality Management Systems. Ability to learn and implement new analytical and synthetic chemistry techniques. Effective communication practices with peers and senior personnel. Flexible approach to structure and workflow management. Commitment to maintaining high standards of precision and cleanliness in laboratory work. Debilitating diseases such as Alzheimer's and Parkinson's affect more than a billion people worldwide. Drawing upon decades of academic research, AltPep was founded to create groundbreaking tools to detect and treat such diseases. Although a young company, AltPep has been recognized for its scientific accomplishment and potential. While still small and nimble, we have grown to a team of thirty talented individuals dedicated to improving the lives of billions. We continue to grow and are looking for talented people to join the team and help us accomplish our mission. We offer competitive compensation to those joining our fight. The compensation range for a Research Associate is $78,000 - $88,000, depending on experience. AltPep takes care of its employees and offers generous stock options, medical, vision, and dental coverage for its employees and their dependents. We understand, and value, life outside of work and offer competitive PTO so you can rest and recharge.
    $78k-88k yearly 5d ago
  • Research Associate I, Digital Biotechnologies

    Adaptive Biotechnologies 3.8company rating

    Research scientist job in Seattle, WA

    At Adaptive, we're Powering the Age of Immune Medicine. Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated. As an Adapter, you'll have the opportunity to make a difference in people's lives. With Adaptive, you'll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application. It's time for your next chapter. Discover your story with Adaptive. Position Overview Adaptive is seeking an exceptional Research Associate I to join a new subsidiary spinout, Digital Biotechnologies Inc. The Scientist will play a critical role in helping to develop a “Next” Next Generation Sequencing (NGS) instrument specifically designed for clinical medicine. Present methods for high-throughput sequencing are not suitable for many clinical applications, as all current NGS platforms lack the combination of high accuracy, rapid turnaround time, and low cost that would lead to robust clinical utility. In collaboration with academic and industry scientists across the country, Digital Biotechnologies is engineering the first solid-state sequencer with the specifications necessary for a widely applicable clinical sequencing instrument. In this role, the Research Associate I, performs assigned experiments or other related work under close supervision, which leverage Digital's novel intellectual property to realize the company's strategic objectives in fundamental science, health care and business development. Key Responsibilities and Essential Functions Synthesis and characterization of inorganic and organic nanomaterials. Routine microscopy (e.g., atomic force microscopy (AFM), transmission electron microscopy (TEM), optical microscopy) and image analysis. Prepare samples following a provided experimental plan. Conduct experiments or other related work based on provided protocols. With guidance, collates and interprets data and synthesizes results into a conclusion. Ability to execute experiments efficiently in a wet lab and suggest process improvements. Recognize patterns or inconsistencies when assessing results and share with supervisor. Position Requirements (Education, Experience, Other) Required Bachelor's degree in chemistry, materials science, nanotechnology, engineering (biomedical, chemical, material), physics, or other related field. Applicants should have 1+ years experience working in a laboratory. Ability to work closely and collaboratively with a team of other researchers. Preferred Experience in nanoparticle, nanomaterials, and/or chemical synthesis. Experience in electron and/or scanning probe microscopy. Experience working with DNA and related molecular biology techniques (e.g., purification, quantification, NGS). Working Conditions Job requires working in a lab and may require handling hazardous chemicals, biological material including blood, bone marrow, and tissue. Work occasionally requires flexible and/or extended hours. Physical Requirements Staff may have to periodically spend extended periods of time standing/sitting within the lab while executing repetitive work, which also includes: Lift Lift >20 pounds occasionally Lift/move large freezers and fridges with the assistance of dollies and carts Occasionally spend Constant work in labs, following all guidelines and protective measures. Compensation Hourly Rate: $26.88 - $40.33 Possible “other compensation” elements to include: equity grant ALERT: Malicious groups posing as Adaptive employees have recently used fraudulent email aliases to extend employment offers, provide fake documents, and request sensitive personal and financial information. Legitimate Adaptive employment opportunities are initiated through our careers page and extended after multiple interviews with verified employees. Adaptive does not ask new hires to purchase anything out-of-pocket, including home office supplies and equipment. Interested in this position, but don't meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn't match all the qualifications; you may be the exact candidate we're searching for! Adaptive is not currently sponsoring candidates requiring work authorization support for this position. Adaptive's posted compensation information includes a base salary (or hourly rate) range and summary of other available total compensation. The base salary range represents a minimum-to-maximum salary (or hourly rate) available to candidates upon extension of offer. Base salary is thoughtfully considered upon offer and is determined through multiple evaluation checks throughout the interview process, including: a candidate's ability to meet minimum qualifications (skills/experience/education), a candidate's ability to thoughtfully address preferred qualifications, current market conditions, and internal pay equity. Listed base salary is exclusive of bonus, commission, equity, differential pay, benefits, and other incentives. Adaptive's benefits at-a-glance. Adaptive Biotechnologies is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against based on disability. Please refer the “Know Your Rights: Workplace Discrimination is Illegal” Poster for more information. If you'd like to view a copy of the company's affirmative action plan or policy statement, please email **********************. If you have a disability and you believe you need a reasonable accommodation to search for a job opening or to submit an online application, please e-mail accommodations@adaptivebiotech.com. This email is created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response. NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.
    $26.9-40.3 hourly Auto-Apply 16d ago
  • Scientist - ADC Biology

    Lancesoft 4.5company rating

    Research scientist job in Bothell, WA

    Scientist (non PhD) Client Biology As a Scientist (non-PhD) on our Client Biology team, you will be a key driver in advancing next-generation Client technologies through collaborative, cross-functional research that spans from early discovery to pre-clinical development. You will develop assays and execute screening and identification of Client chemotypes that function as payloads for antibody drug conjugates for cancer therapy. You will work collaboratively with chemistry and other cross functional teams to understand mechanism of action of identified payloads. You will analyze, interpret and communicate the data effectively to key stake holders. KEY RESPONSIBILITIES Apply cellular, biochemical, immunological, and molecular biology laboratory techniques to preclinical research projects in the areas of Cancer signaling and Cancer biology Investigate MOAs of our therapeutics through development, optimization, and execution of complex assays Interact and collaborate with other functional groups across research Provide leadership within technical area of expertise;may train, direct or mentor others Design and execute key experiments to investigate Client therapeutic targets and MOAs of Client payloads to enable clear go/no-go decisions. Independently analyze data, document results, and present findings to large and small audiences Maintain rigorous records of experimental progress using electronic laboratory notebooks Present experimental results and scientific rationale to colleagues Execute molecular, biochemcial and cell-based methodologies including cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescence and live cell microscopy. Aid in execution and analysis of additional experiments as need arises within the Client discovery research team MINIMUM REQUIREMENTS Bachelor's degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field and 6+ years' relevant industry experience OR M.S. Degree in Cellular or Molecular Biology, Immunology, Biochemistry or related field with 4+ years' relevant industry experience Experience with Microsoft Office (Excel, Word, PowerPoint) and analytical (Prism, FlowJo, etc.) software programs Experience designing, performing and interpreting complex experiments that require significant insight into problems being addressed with some guidance Working knowledge in specific areas of Cancer Biology and Cancer therapeutics esp, small molecule agents, Biologics and ADCs Experience working independently and working on multiple projects Experience collaborating across teams and a variety of disciplines to provide experimental expertise and support others on joint projects Experience leading parts of projects or initiatives within area of expertise Excellent written/oral communication skills with experience presenting/sharing details of the work with key stake holders PREFERRED REQUIREMENTS Experience in experimental cancer biology, biochemical and/or immunological techniques (e.G., Cell culture, cytotoxicity assays, HiBit, HTRF, ELISA, western blotting, automated liquid handling multicolor flow cytometry, immunofluorescent and live cell microscopy.). Background knowledge of the field of cell signaling and biochemistry Experience developing complex cell and biochemical assays
    $82k-113k yearly est. 9d ago
  • Senior Research Associate/Scientist I

    Outpace Bio

    Research scientist job in Seattle, WA

    About Outpace BioOutpace Bio is pioneering the future of cell therapy for solid tumors by harnessing unrivaled AI-powered protein design. Our mission is to program immune cells for enhanced function inside patients, overcoming key barriers such as poor tumor access, weak survival, antigen escape, and dose-related toxicity. By creating and integrating modular, plug-and-play technology assets, we are developing cell therapies with unprecedented efficacy, transforming how engineered T cells interact with cancer and the immune system to deliver life-changing outcomes. Our multidisciplinary team of scientists, engineers, coders, and cell therapy developers works at the cutting edge of computational protein design, synthetic biology, and immunology. Together, we are reimagining how cells function to unlock novel therapeutic possibilities.Located in Seattle's vibrant biotech hub overlooking scenic South Lake Union, Outpace Bio is led by pioneers in computational protein design and engineered cell therapies. Our culture is built on a foundation of respect and inclusion, which are fundamental to how we collaborate to revolutionize cell therapy through groundbreaking innovation rooted in rigorous science. Our Commitment to DiversityAt Outpace Bio, we believe that the highest performing teams include people from a wide variety of backgrounds and experiences. We are committed to cultivating an open, diverse, and inclusive culture for all employees. Recognizing that the best candidates do not always match all criteria of the job description, we encourage you to apply if you think you would be a good fit for the role and are inspired by our mission to cure disease by pushing the boundaries of biology. Our MomentumIn August 2024, Outpace Bio secured an oversubscribed $144 million Series B financing, led by RA Capital Management and supported by a premier syndicate of life science investors. This funding accelerates our pipeline of programmed T cell therapies, including our lead candidate OPB-101, a mesothelin-specific chimeric antigen receptor (CAR) T cell enhanced by Outpace's proprietary OUTSMART™, OUTLAST™, OUTSPACER™, and OUTSAFE™ technologies. OPB-101 is advancing toward IND clearance and first dosing in 2025 for patients with advanced platinum-resistant ovarian cancers. The Series B investment also supports the expansion of our pipeline, enabling us to develop additional transformative therapies leveraging our innovative plug-and-play technology platform. We are seeking a Senior Research Associate or Scientist I to join the viral vector production team at Outpace Bio. In this role, you will apply your scientific training and technical expertise to produce, purify, and characterize lentivirus for our cell and gene therapy applications. Working collaboratively with our Immunology, In vivo, and Cloning teams, you will ensure timely delivery of high-quality viral vectors while contributing to the development of novel viral assays and scale-up process development and improvement. Successful candidates will bring strong technical skills in mammalian cell culture, viral vector systems, viral vector process development, viral downstream purification, and analytical techniques including flow cytometry and molecular quantitation methods. We seek motivated, detail-oriented scientists who can work independently, troubleshoot technical challenges, and optimize protocols to advance our research programs. If you are a collaborative team player with strong problem-solving skills and enthusiasm for translating research into therapeutic impact, you will thrive in our fast-paced startup environment.Responsibilities (Position responsibilities may include, but are not limited to): Produce and characterize lentivirus supporting multiple Outpace research and pipeline programs Design and execute optimization experiments to improve viral titers, purity, and production efficiency Support scale-up of lentiviral production for process development and preclinical in vivo studies Perform and optimize functional titer and genome quantitation assays (flow cytometry, dd PCR/dPCR) Contribute to the development of improved upstream and downstream vector production and purification methodologies Contribute to experiment design, data analysis, and presentation of results in internal meetings Contribute to authoring or reviewing protocols, reports, or regulatory filings. Qualifications (Required): Ability to work independently on experimental design, execution, and troubleshooting Proficiency in mammalian cell culture and aseptic technique Hands-on experience with small-scale lentivirus production (adherent or suspension systems) Working knowledge of chromatography and filtration principles, downstream bioprocessing, and process scale-up Experience operating chromatography systems (AKTA or equivalent) Experience with filtration operations including UF/DF and depth filtration Highly organized with strong attention to detail and data quality Ability to learn new protocols quickly and apply critical thinking to problem-solving Effective scientific communication skills with ability to discuss results and collaborate with team members Experience measuring viral titer by flow cytometry and dd PCR/digital PCR Hands-on experience with transfection and transduction protocols Experience safely handling lentivirus under BSL-2 conditions 3+ years of research experience with mammalian cell culture systems Qualifications (Preferred): Master's or PhD in Virology, Molecular Biology, Immunology, Cell Biology, Gene Therapy, or related field; alternatively, Bachelor's degree with substantial position-relevant research experience in academic or industry setting Lentivirus process development in suspension culture formats (96-well, 24-well, shake flask, and 1-5L bio-reactor scales) Downstream viral vector processing including tangential flow filtration (TFF) and chromatography-based purification Familiarity with molecular biology techniques including nucleic acid isolation, quantification, and PCR-based methods Experience with mammalian cell culture in bioreactor systems Experience in a startup or fast-paced biotech setting Experience with Electronic Lab Notebook (ELN) systems (Benchling) Ability to manage multiple projects, prioritize workflow, meet deadlines, and collaborate effectively in cross-functional teams Familiarity with other viral vector platforms (gamma retrovirus, AAV) The salary range is based on Outpace Bio's reasonable estimate of base salary for this role at the time of posting. Actual base salary will be based on a variety of factors including skills, experience, and other related factors permitted by law. Working at Outpace offers an exciting opportunity to contribute to groundbreaking research that has the potential to transform the lives of people around the world. Outpace Bio Total RewardsFull time employees and their eligible dependents may enroll in Outpace's medical, dental, vision, life insurance, disability, flexible spending account, health savings account, commuter benefits, legal benefits, and 401k plan which includes an employer match. In addition, employees may receive stock option grants to be outlined in their offer of employment and a performance bonus. Outpace employees enjoy flexible PTO, paid sick leave which complies with local requirements, and fifteen paid holidays plus a winter shutdown. Outpace also offers a generous paid parental leave policy to all regular full-time employees. Outpace Bio is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. Applicants must be authorized to work in the United States. If you are legally authorized to work in the United States now, or in the future without any form of sponsorship, we encourage you to apply. Outpace Bio does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Outpace Bio or its employees is strictly prohibited unless contacted directly by Outpace Bio's internal team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Outpace Bio and will not owe any referral or other fees.
    $63k-107k yearly est. Auto-Apply 57d ago
  • Applied Scientist

    Tata Consulting Services 4.3company rating

    Research scientist job in Seattle, WA

    * 3+ years of building models for business application experience * PhD, or Master's degree and 4+ years of CS, CE, ML or related field experience * Experience programming in Java, C++, Python or related language * Experience in any of the following areas: algorithms and data structures, parsing, numerical optimization, data mining, parallel and distributed computing, high-performance computing * Experience building machine learning models or developing algorithms for business application * Experience using Unix/Linux Roles & Responsibilities: * Use deep learning, ML and NLP techniques to create scalable solutions for creation and development of language model centric solutions for building personalized assistant systems based on a rich set of structured and unstructured contextual signals * Innovate new methods for contextual knowledge extraction and information retrieval, using language models in combination with other learning techniques, that allows effective grounding in context providers when considering memory, compute, latency and quality * Work on integration with GenAI models with customer's event management tracking tool. AI Translation/Transcription (such as NovaSonic from AWS) within AWS Connect to generate real-time notes within customer's event management tracking tool. * Research in advanced customer understanding and behavior modeling techniques * Collaborate with cross-functional teams of engineers, product managers, and scientists to identify and solve complex problems in personal knowledge aggregation, processing, modeling, and verification * Design and execute experiments to evaluate the performance of state-of-the-art algorithms and models, and iterate quickly to improve results * Think Big about the arc of development of conversational assistant system personalization over a multi-year horizon, and identify new opportunities to apply these technologies to solve real-world problems * Communicate results and insights to both technical and non-technical audiences, including through presentations and written reports TCS Employee Benefits Summary: * Discretionary Annual Incentive. * Comprehensive Medical Coverage: Medical & Health, Dental & Vision, Disability Planning & Insurance, Pet Insurance Plans. * Family Support: Maternal & Parental Leaves. * Insurance Options: Auto & Home Insurance, Identity Theft Protection. * Convenience & Professional Growth: Commuter Benefits & Certification & Training Reimbursement. * Time Off: Vacation, Time Off, Sick Leave & Holidays. * Legal & Financial Assistance: Legal Assistance, 401K Plan, Performance Bonus, College Fund, Student Loan Refinancing. #LI-RJ2 Salary Range - $120,000-$200,000 a year
    $70k-90k yearly est. 44d ago
  • Research Associate, QC/Oligo Manufacturing

    Customarray

    Research scientist job in Redmond, WA

    Full-time Description We are looking for a dedicated and hardworking research associated to join a cross-disciplinary team to help us develop and support advanced oligonucleotide synthesis technologies and applications. The candidate will handle multiple roles across our R&D teams to support both routine and investigatory laboratory activities. Knowledge of oligonucleotide synthesis chemistry, PCR and qPCR techniques, and library preparation for next-generation sequencing are desirable, but training will be provided. Level of the position will be commensurate with the qualifications of the final candidate. Location: Redmond, WA Key Responsibilities: Perform array-based oligonucleotide synthesis on CustomArray's CMOS semiconductor synthesis platform. Perform QC operations on CustomArray products including PCR/qPCR and hybridization assays. Perform NGS library preparation and sequencing work according to established protocols. Familiarity with Illumina NGS platform desirable. Contribute observations and experience to R&D team to accelerate pace of technology development. Conduct routine lab maintenance procedures. Requirements Bachelor's degree in Biology or Chemistry related field with 2 years of hands-on experience. Master's degree a plus. Working knowledge of oligonucleotide synthesis desirable. Experience with surface chemistry techniques and electrochemistry desirable. Good grasp of basic molecular biology techniques including PCR, qPCR, array-based hybridization assays, and NGS. Familiarity with vacuum instrumentation and surface coating/modification techniques highly desirable Ability to work as part of a small cross-disciplinary team to accomplish both short term and long term goals. GenScript USA Inc. is a proud equal opportunity employer - Veterans/Disabled and other protected categories. We are committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is GenScript's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex, pregnancy (including childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, military and veteran status, or any other characteristic protected by law. GenScript USA Inc. maintains a drug-free workplace.
    $43k-67k yearly est. 60d+ ago
  • Associate Scientist 3

    Weston Solutions Inc. 4.5company rating

    Research scientist job in Seattle, WA

    At Weston Solutions, Inc. you will do meaningful work and make valuable contributions. Employee-ownership at Weston is a path to professional growth and access to diverse opportunities in a highly connected community that works together across key service areas to make a difference in the environment. Weston continues to evolve and adapt to our changing world as a premier provider of environmental and infrastructure services for over sixty years. In both the public and private sectors our teams help identify, solve, mitigate, and manage critical environmental issues to help clients achieve a more sustainable future. Weston Solutions, Inc. is seeking a mid-level Associate Geologist, Engineer, or Scientist to work with our Superfund Technical Assessment and Response Team (START) performing EPA Investigations, Removal Assessments, and Removal Actions, as well as supporting other federal clients within the Pacific Northwest. This candidate will work within the federal teams providing our clients with accurate and pertinent scientific data according to methods, procedures, and techniques agreed upon. The candidate will provide leadership within a team responsible for delivering sound conclusions and recommendations to clients based upon field investigations and literature reviews within the established project schedules. The position will also be periodically on-call to support EPA emergency response projects as needed. Location: Seattle, WA Knowledge, Skills & Abilities: * B.S. in a Science and 4-6 years of experience in environmental and/or geotechnical sampling, and/or removal oversight. Oil and hazardous materials emergency response experience is a plus. * Ability to plan, lead, and participate in site walks, site evaluations, removal assessments, and removal action oversight projects, including oil, and hazardous materials emergency response projects. * Experience performing site assessments and collecting multimedia samples. * Exposure to various technical and scientific procedures * Ability to lift to 50 lbs. (field equipment, PPE, etc.) * Experience in preparing planning documents to methodically perform field investigations, data reporting, technical report preparation. * Strong organization and communication skills. * Attention to detail and self-starter * Ability to be flexible and adaptable. * Proficiency in Microsoft Office and Adobe Acrobat * Provide technical direction for teams up to 10+ personnel. Preferred Skills: * A minimum of four years multimedia sampling. Preferred experience in analytical method selection and data management and interpretation * Field instrumentation. Proficient in the use of various air and water monitoring instruments (PID/FID, multi gas meters, etc.). Abilities include calibration of field instruments, implementation in field, and interpretation of results. * Familiarity with the Incident Command System (ICS) 100-800. Completion of ICS courses a plus. * General understanding of the NCP, Oil Pollution Act and CERCLA. * 40-Hour HAZWOPER * Able to work in Levels C/B/A PPE Technical and Operational Scope: * Identifies staff in alignment with tasking, plan, and document field activities, and prepare daily and final reports for EPA and other federal clients within established budgets and schedule. * Exercises judgment on applicability of methods and approaches in use and determines best approaches to problem solving when standard procedures are inadequate. * Determines best method of data gathering, database management, and analysis of data to achieve goals. * Consults with outside specialists to obtain most accurate and timely data possible while meeting project specifications and timetables. * Calibrates and maintains a variety of multi-media monitoring and sampling equipment. * Knowledge of preparing cost estimates and scope of work for project execution. * Proficient in the writing of technical documents including sampling, data, and safety plans. * Use level D-A PPE to make entries into potentially hazardous areas. * Duties may include rotations as an "on-call" responder available 24 hours a day for one week at a time, and periodic Hazmat and oil spill emergency responses/removal assessment/action assignments. We fully invest in our people: Weston provides a generous, comprehensive benefits package program that offers employees high value options with solid financial protection, meeting the personal needs of its people and their families. * Medical, Dental, Vision, 401K with base and matching employer stock contributions. * Paid time off includes personal, holiday, and parental leave. * Life and disability plans. * Critical illness and accident plans. * Work/Life flexibility. * Professional development opportunities. Compensation will vary based upon experience, education, skill level, and other compensable factors.
    $57k-82k yearly est. Auto-Apply 60d+ ago

Learn more about research scientist jobs

How much does a research scientist earn in Bothell, WA?

The average research scientist in Bothell, WA earns between $50,000 and $132,000 annually. This compares to the national average research scientist range of $58,000 to $137,000.

Average research scientist salary in Bothell, WA

$81,000

What are the biggest employers of Research Scientists in Bothell, WA?

The biggest employers of Research Scientists in Bothell, WA are:
  1. Meta
  2. Microsoft
  3. ManpowerGroup
Job type you want
Full Time
Part Time
Internship
Temporary