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The average salary for a Senior Applications Scientist in the United States is approximately $105,538 annually, translating to about $51 per hour. Salaries can vary widely based on factors such as geographic location, industry, and years of experience.
In states like California and New York, salaries tend to be higher, often exceeding the national average. For example, the highest paying states for this role typically include:
Additionally, positions in biotechnology or pharmaceuticals often provide more lucrative compensation packages. As a Senior Applications Scientist, you can expect not only competitive salaries but also opportunities for advancement and specialization in your field.
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The average senior applications scientist salary in Rhode Island, California, and New Jersey are the highest in the U.S. The lowest average senior applications scientist salary states are North Dakota, South Carolina, and Iowa.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | California | $121,461 | $58.39 |
| 2 | New Jersey | $118,201 | $56.83 |
| 3 | Rhode Island | $121,797 | $58.56 |
| 4 | Connecticut | $109,021 | $52.41 |
| 5 | Maryland | $108,006 | $51.93 |
| 6 | Delaware | $102,185 | $49.13 |
| 7 | Maine | $106,697 | $51.30 |
| 8 | Massachusetts | $94,995 | $45.67 |
| 9 | Nevada | $107,666 | $51.76 |
| 10 | New York | $95,389 | $45.86 |
| 11 | Virginia | $92,667 | $44.55 |
| 12 | Minnesota | $99,585 | $47.88 |
| 13 | Montana | $93,502 | $44.95 |
| 14 | Oregon | $92,751 | $44.59 |
| 15 | Alaska | $95,603 | $45.96 |
| 16 | Pennsylvania | $88,589 | $42.59 |
| 17 | Vermont | $88,958 | $42.77 |
| 18 | Arizona | $92,667 | $44.55 |
| 19 | New Hampshire | $87,624 | $42.13 |
| 20 | Indiana | $91,588 | $44.03 |
| 21 | Washington | $86,336 | $41.51 |
| 22 | Michigan | $88,992 | $42.78 |
| 23 | Tennessee | $89,038 | $42.81 |
| 24 | North Carolina | $77,530 | $37.27 |
| 25 | New Mexico | $78,376 | $37.68 |
| 26 | West Virginia | $84,441 | $40.60 |
| 27 | District of Columbia | $82,931 | $39.87 |
| 28 | Hawaii | $90,535 | $43.53 |
| 29 | Ohio | $79,670 | $38.30 |
| 30 | Wisconsin | $77,555 | $37.29 |
| 31 | Idaho | $78,047 | $37.52 |
| 32 | Texas | $78,162 | $37.58 |
| 33 | Illinois | $76,285 | $36.68 |
| 34 | Colorado | $76,771 | $36.91 |
| 35 | Wyoming | $73,102 | $35.15 |
| 36 | Oklahoma | $78,022 | $37.51 |
| 37 | South Dakota | $65,083 | $31.29 |
| 38 | Arkansas | $75,477 | $36.29 |
| 39 | North Dakota | $64,990 | $31.25 |
| 40 | Kentucky | $72,629 | $34.92 |
| 41 | Utah | $65,765 | $31.62 |
| 42 | Florida | $71,982 | $34.61 |
| 43 | Kansas | $65,421 | $31.45 |
| 44 | Mississippi | $68,640 | $33.00 |
| 45 | Georgia | $67,935 | $32.66 |
| 46 | Alabama | $67,056 | $32.24 |
| 47 | Iowa | $63,404 | $30.48 |
| 48 | South Carolina | $63,456 | $30.51 |
| 49 | Nebraska | $62,663 | $30.13 |
| 50 | Missouri | $55,167 | $26.52 |
| 51 | Louisiana | $62,187 | $29.90 |
The highest-paying cities for senior applications scientists are Rohnert Park, CA, Woodbridge, NJ, and Annapolis, MD.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Rohnert Park, CA | $129,477 | $62.25 |
| 2 | Woodbridge, NJ | $118,521 | $56.98 |
| 3 | Annapolis, MD | $108,523 | $52.17 |
| 4 | Newark, DE | $102,121 | $49.10 |
| 5 | New York, NY | $95,694 | $46.01 |
| 6 | Boston, MA | $95,185 | $45.76 |
| 7 | Kingsport, TN | $92,955 | $44.69 |
| 8 | Salem, OR | $92,867 | $44.65 |
| 9 | Chandler, AZ | $92,573 | $44.51 |
| 10 | Indianapolis, IN | $91,102 | $43.80 |
| 11 | Akron, OH | $81,537 | $39.20 |
| 12 | Raleigh, NC | $79,047 | $38.00 |
| 13 | Austin, TX | $78,219 | $37.61 |
| 14 | Elk Grove Village, IL | $76,739 | $36.89 |
| 15 | Boulder, CO | $76,193 | $36.63 |
| 16 | Tulsa, OK | $74,924 | $36.02 |
| 17 | Tallahassee, FL | $72,719 | $34.96 |
| 18 | Atlanta, GA | $67,682 | $32.54 |
| 19 | American Fork, UT | $66,085 | $31.77 |
| 20 | Cedar Rapids, IA | $64,167 | $30.85 |
A senior applications scientist's salary ranges from $69,000 a year at the 10th percentile to $159,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $159,000 | $13,250 | $76 |
| 75th Percentile | $131,000 | $10,917 | $63 |
| Average | $105,538 | $8,795 | $51 |
| 25th Percentile | $84,000 | $7,000 | $40 |
| 10th Percentile | $69,000 | $5,750 | $33 |
The highest paying types of senior applications scientists are medical science liaison, principal scientist, and senior scientist.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Research Fellow | $53,823 | $4,485 | $25.88 | 59,746 |
| Fellow | $66,364 | $5,530 | $31.91 | 7,459 |
| PHD Researcher | $51,634 | $4,303 | $24.82 | 19,736 |
| Researcher | $67,145 | $5,595 | $32.28 | 30,498 |
| Doctoral Fellow | $53,366 | $4,447 | $25.66 | 22,661 |
| Postdoctoral Scholar | $57,587 | $4,799 | $27.69 | 18,983 |
Top companies hiring senior applications scientists now:
Senior applications scientist salaries at Schrödinger and Nanometrics are the highest-paying according to our most recent salary estimates. In addition, the average senior applications scientist salary at companies like Waters and Arkema are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Schrödinger Inc | $125,944 | $60.55 |
| 2 | Nanometrics | $118,238 | $56.85 |
| 3 | Waters | $117,380 | $56.43 |
| 4 | Arkema | $117,343 | $56.41 |
| 5 | Eastman | $114,929 | $55.25 |
| 6 | Shimadzu Corporation | $110,768 | $53.25 |
| 7 | Beckman Coulter | $110,553 | $53.15 |
| 8 | Quidel | $109,745 | $52.76 |
| 9 | Maxim Integrated | $109,143 | $52.47 |
| 10 | Agilent Technologies | $107,444 | $51.66 |
| 11 | IDEX | $105,066 | $50.51 |
| 12 | Givaudan | $104,939 | $50.45 |
| 13 | Danisco US Inc | $104,590 | $50.28 |
| 14 | Edlong: Everything Dairy Can Be | $104,548 | $50.26 |
| 15 | A+ Products | $103,939 | $49.97 |
| 16 | SCIEX | $103,733 | $49.87 |
| 17 | PerkinElmer | $101,449 | $48.77 |
| 18 | Caliper Life Sciences | $100,475 | $48.31 |
| 19 | Advion | $100,179 | $48.16 |
| 20 | Sentient Energy | $100,128 | $48.14 |
The average senior applications scientist salary has risen by $17,738 over the last ten years. In 2014, the average senior applications scientist earned $87,800 annually, but today, they earn $105,538 a year. That works out to a 14% change in pay for senior applications scientists over the last decade.
Compare senior applications scientist salaries for cities or states with the national average over time.
Compare senior applications scientist salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $106,000 | $50.74 | +3.0% |
| 2024 | $102,000 | $49.23 | +4.5% |
| 2023 | $97,800 | $47.02 | +3.2% |
| 2022 | $94,700 | $45.52 | +1.9% |
| 2021 | $92,900 | $44.65 | -2.1% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| PGP International | SR. Application Scientist | Chicago, IL | 06/20/2025 | $110,000 |
| Exact Sciences | Senior Application Scientist, Technical Services | Madison, WI | 04/26/2025 | $109,000 |
| Cadence Design Systems, Inc. | Senior Application Scientist Manager | San Jose, CA | 04/16/2025 | $141,400 |
| Exact Sciences | Senior Application Scientist, Technical Services | Madison, WI | 03/30/2025 | $109,000 |
| Cellares Corporation | Senior Applications Scientist (I, II, III) | Bridgewater, NJ | 02/19/2025 | $90,000 |
| Exact Sciences Corporation | Senior Application Scientist, Technical Services | Madison, WI | 02/18/2025 | $109,000 |
| Cellares | Senior Applications Scientist (I, II, III) | South San Francisco, CA | 02/18/2025 | $90,000 |
| Cellares Corporation | Senior Applications Scientist (I, II, III) | San Francisco, CA | 02/17/2025 | $90,000 |
| Cellares | Senior Applications Scientist (I, II, III) | South San Francisco, CA | 01/27/2025 | $90,000 |
| Kerry | Senior Application Scientist | Beloit, WI | 01/25/2025 | $89,084 |
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