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Senior research investigator vs principal investigator

The differences between senior research investigators and principal investigators can be seen in a few details. Each job has different responsibilities and duties. It typically takes 2-4 years to become both a senior research investigator and a principal investigator. Additionally, a senior research investigator has an average salary of $90,336, which is higher than the $84,635 average annual salary of a principal investigator.

The top three skills for a senior research investigator include data analysis, drug discovery and chemistry. The most important skills for a principal investigator are patients, data collection, and project management.

Senior research investigator vs principal investigator overview

Senior Research InvestigatorPrincipal Investigator
Yearly salary$90,336$84,635
Hourly rate$43.43$40.69
Growth rate17%5%
Number of jobs62,24844,475
Job satisfaction--
Most common degreeBachelor's Degree, 72%Bachelor's Degree, 53%
Average age4147
Years of experience44

What does a senior research investigator do?

A Senior Research Investigator specializes in conducting extensive research and analysis to develop conclusions and recommendations. Although the extent of their responsibilities depends on their place or employment industry, it usually includes adhering to guidelines and timelines, narrowing down leads to gather and analyze data, consulting with experts, and maintaining records of all procedures. As a Senior Research Investigator, it is essential to lead and serve as a role model to less experienced investigators in the joint effort to reach project goals, all while implementing the facility's standards and regulations.

What does a principal investigator do?

A Principal Investigator is the primary person who is responsible for designing, conducting, and reporting a research project. They report to a designated official such as the department head or division chief.

Senior research investigator vs principal investigator salary

Senior research investigators and principal investigators have different pay scales, as shown below.

Senior Research InvestigatorPrincipal Investigator
Average salary$90,336$84,635
Salary rangeBetween $58,000 And $139,000Between $59,000 And $120,000
Highest paying CitySan Francisco, CASan Francisco, CA
Highest paying stateAlaskaCalifornia
Best paying companyCrunchbaseIncyte
Best paying industryPharmaceuticalTechnology

Differences between senior research investigator and principal investigator education

There are a few differences between a senior research investigator and a principal investigator in terms of educational background:

Senior Research InvestigatorPrincipal Investigator
Most common degreeBachelor's Degree, 72%Bachelor's Degree, 53%
Most common majorChemistryPsychology
Most common collegeDuke UniversityUniversity of Michigan - Ann Arbor

Senior research investigator vs principal investigator demographics

Here are the differences between senior research investigators' and principal investigators' demographics:

Senior Research InvestigatorPrincipal Investigator
Average age4147
Gender ratioMale, 57.8% Female, 42.2%Male, 52.2% Female, 47.8%
Race ratioBlack or African American, 6.2% Unknown, 4.1% Hispanic or Latino, 9.4% Asian, 24.9% White, 55.2% American Indian and Alaska Native, 0.1%Black or African American, 10.3% Unknown, 4.0% Hispanic or Latino, 14.0% Asian, 4.3% White, 66.7% American Indian and Alaska Native, 0.7%
LGBT Percentage8%16%

Differences between senior research investigator and principal investigator duties and responsibilities

Senior research investigator example responsibilities.

  • Process, analyze and upload HTS data that lead to the discovery of new structural classes of small molecules.
  • Develop molecular analysis methods and cell-base assays for RNA interference (RNAi) and oligonucleotide decoy projects.
  • Provide scientific support for CA125, a monoclonal antibody cancer immunotherapy program.
  • Probe compound/receptor-ligand complexes by establishing mammalian reporter cell lines and biochemical competition assays with FACS and ELISA endpoints.
  • Supervise activities of analytical cellular and molecular immunology laboratories.
  • Supervise activities of analytical cellular and molecular immunology laboratories.

Principal investigator example responsibilities.

  • Serve chemistry project leads for two early-stage drug discovery projects.
  • Design, build and manage CADD, NMR and MRI facilities.
  • Attain IRB approval, recruit participants, analyze the data and present results
  • Manage outsource projects, and interact with vendors for API sourcing, and device components base on project needs.
  • Conduct research using industry standards: GCP, GLP, SORP and compliance with IRB.
  • Receive IRB approval and clearance for research
  • Show more

Senior research investigator vs principal investigator skills

Common senior research investigator skills
  • Data Analysis, 11%
  • Drug Discovery, 6%
  • Chemistry, 6%
  • Visualization, 5%
  • BMS, 5%
  • RNA, 4%
Common principal investigator skills
  • Patients, 10%
  • Data Collection, 9%
  • Project Management, 8%
  • Technical Reports, 6%
  • FDA, 4%
  • Data Analysis, 4%

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