Senior Machine Learning and Quantum Chemistry Scientist (M/F)
Qubit Pharmaceuticals
Senior scientist job in Boston, MA
Qubit Pharmaceuticals is a French-American deeptech startup, focusing on discovering novel molecules for complex targets in healthcare and materials science. We leverage proprietary molecular simulation and quantum-physics based modeling technology to develop our own discovery programs that we either co-develop with or license out to pharmaceutical and industrial partners. This enables us to design more effective and safer drug candidates, aiming to significantly reduce the time and investment needed for discovery. In just 18 months, Qubit Pharmaceuticals grew its portfolio to 7 programs in oncology, immunology & antivirals.
Our cutting-edge technology is based on over 30 years of research by our academic founders, and relies on three main components: in-depth expertise in computational science and high-performance computing (HPC), quantum chemistry and artificial intelligence algorithms, and a powerful, automated cloud platform for molecular simulation with chemical accuracy. We recently announced the launch of the world's most powerful AI foundation model for molecular simulation.
Qubit Pharmaceuticals is looking for an Senior Machine Learning and Quantum Chemistry Scientist to lead the development of foundation models for chemistry.
The perfect fit for this job
At Qubit Pharmaceuticals, we are looking for a Senior Machine Learning and Quantum Chemistry Scientist who is quick at adapting to new challenges and issues. This person will be eager to learn, meet the needs of users, and work in a collaborative process with teammates and across multiple teams.
Your role
As a member of the Research team, you will be responsible for the Quantum Chemistry Foundation Model development, including molecules quantum datasets selection, model training, coding, testing and validation.
Develop new methods to solve practical and challenging problems in Machine Learning and Quantum Chemistry applied to chemistry & drug discovery
Communicate the results of your research by filing patent applications, publishing peer-reviewed papers and giving presentations at research conferences
Provide technical support to users
Your qualifications and skills
Master degree or equivalent in Applied Maths / Computer Science / Chemistry
PhD in Quantum Chemistry and Machine learning is strongly preferred
Minimum of 5 years work experience (including PhD) is required
Knowledge of quantum chemistry is strongly preferred
Proficiency in active learning, architecture, and training methods, related to Machine Learning Force Field, Machine Learning Interaction Potentials, Neural Networks Potentials
Ability to motivate and lead a project team
Excellent communication skills for explaining complex concepts to non-specialists
Agility in a startup environment (changing priorities, multiple projects)
Open-source code development and maintenance is valuable
The proposal benefits & perks
Duration: Full time - Permanent
Starting from October 2025
Salary according to profile
Health insurance and provident fund 100% covered
Lunch vouchers worth €9 covered at 50%.
Location: Paris 14th arrondissement / Boston
Possibility of remote work for 2 days per week.
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$86k-119k yearly est. 5d ago
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Senior Machine Learning Scientist II
Out In Science, Technology, Engineering, and Mathematics
Senior scientist job in Boston, MA
Join Axon and be a Force for Good.
At Axon, we're on a mission to Protect Life. We're explorers, pursuing society's most critical safety and justice issues with our ecosystem of devices and cloud software. Like our products, we work better together. We connect with candor and care, seeking out diverse perspectives from our customers, communities and each other.
Life at Axon is fast-paced, challenging and meaningful. Here, you'll take ownership and drive real change. Constantly grow as you work hard for a mission that matters at a company where you matter.
Your Impact
We are seeking highly skilled and innovative Computer Vision and Machine Learning Scientist to join our AI team, focusing on AI applications in Cloud, Devices and Robotics. As a key member of our research and development efforts, you will play a crucial role in advancing the state-of-the-art in Multimodal Large Language Models (MLLMs), Computer Vision technologies for our cloud, devices and robotics. You will collaborate with cross-functional teams to design, develop, and deploy cutting-edge computer vision algorithms and solutions that enable intelligent perception and understanding of visual data.
What You'll Do
Location: Hybrid in Seattle OR Remotely from the US
Reports to: Senior Manager, Research Science
Own one or more key technical areas across CVML product portfolio.
Provide technical leadership to junior scientists, guiding the transition of R&D concepts into impactful CVML product feature.
Research and develop cutting-edge techniques in MLLMs, GenAI, and Computer Vision across cloud, devices and sensors based data sources.
Design and implement efficient and scalable MLLM models for inference and analysis of visual data.
Explore novel approaches to address challenges in object detection, recognition, tracking, segmentation, and scene understanding.
Optimize algorithms for performance, memory footprint, and energy efficiency to meet the requirements of resource-constrained devices.
Join forces with MLEs or firmware or hardware engineers to leverage hardware accelerators and optimize algorithms for specific hardware architectures.
Evaluate the performance of MLLM models using real-world datasets and design experiments to validate their effectiveness.
Stay up-to-date with the latest research trends and advancements in computer vision, machine learning, and deep learning, MLLMs, GenAI and integrate relevant findings into our projects.
Contribute to patent disclosures, academic publications, and technical documentation to share insights and findings with the broader community.
Experience coach and mentor junior scientists.
What You Bring
PhD and with +8 year experience in Computer Science or a related field with a focus on MLLMs, computer vision, machine learning, or artificial intelligence.
Proven track record of research excellence in machine learning, computer vision, robotics perception, demonstrated through publications in top-tier conferences or journals.
Strong proficiency in programming languages such as Python, C/C++, experience with deep learning frameworks such as TensorFlow, PyTorch, or Keras and experience with ROS or robotic operational system.
Drive one or more phases of the ML development lifecycle: shape datasets, investigate modeling approaches and architectures, train/evaluate/tune models and implement the end-to-end training pipeline.
Leverage state-of-the-art research to deliver high quality models enabling multiple AI projects at scale.
Contribute back to the research community via academic publications, tech blogs, open-source code and contributing to internal/external AI challenges
Experience in developing computer vision algorithms for resource-constrained devices such as mobile phones, IoT devices, or embedded systems is highly desirable.
Excellent problem-solving skills, analytical thinking, and the ability to work autonomously as well as collaboratively in a team environment.
Well-developed communication skills and the ability to effectively present complex technical concepts to both technical and non-technical audiences.
Benefits that Benefit You
Competitive salary and 401k with employer match
Discretionary paid time off
Paid parental leave for all
Medical, Dental, Vision plans
Fitness Programs
Emotional & Mental Wellness support
Learning & Development programs
And yes, we have snacks in our offices
Benefits listed herein may vary depending on the nature of your employment and the location where you work
The Pay: Axon is a total compensation company, meaning compensation is made up of base pay, bonus, and stock awards. The starting base pay for this role is between USD 181,000 in the lowest geographic market and USD 266,000 in the highest geographic market.The actual base pay is dependent upon many factors, such as: level, function, training, transferable skills, work experience, business needs, geographic market, and often a combination of all these factors. Our benefits offer an array of options to help support you physically, financially and emotionally through the big milestones and in your everyday life. To see more details on our benefits offerings please visit ******************************
Don't meet every single requirement? That's ok. At Axon, we Aim Far. We think big with a long-term view because we want to reinvent the world to be a safer, better place. We are also committed to building diverse teams that reflect the communities we serve.
Studies have shown that women and people of color are less likely to apply to jobs unless they check every box in the . If you're excited about this role and our mission to Protect Life but your experience doesn't align perfectly with every qualification listed here, we encourage you to apply anyways. You may be just the right candidate for this or other roles.
Important Notes
The above is not intended as, nor should it be construed as, exhaustive of all duties, responsibilities, skills, efforts, or working conditions associated with this job. The job description may change or be supplemented at any time in accordance with business needs and conditions.
Some roles may also require legal eligibility to work in a firearms environment.
Axon's mission is to Protect Life and is committed to the well-being and safety of its employees as well as Axon's impact on the environment. All Axon employees must be aware of and committed to the appropriate environmental, health, and safety regulations, policies, and procedures. Axon employees are empowered to report safety concerns as they arise and activities potentially impacting the environment.
We are an equal opportunity employer that promotes justice, advances equity, values diversity and fosters inclusion. We're committed to hiring the best talent - regardless of race, creed, color, ancestry, religion, sex (including pregnancy), national origin, sexual orientation, age, citizenship status, marital status, disability, gender identity, genetic information, veteran status, or any other characteristic protected by applicable laws, regulations and ordinances - and empowering all of our employees so they can do their best work. If you have a disability or special need that requires assistance or accommodation during the application or the recruiting process, please ***************************. Please note that this email address is for accommodation purposes only. Axon will not respond to inquiries for other purposes.
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$86k-119k yearly est. 2d ago
ADME-PK Principal Scientist, Preclinical Development
Dyne Tx
Senior scientist job in Waltham, MA
A biotechnology company in Waltham, MA is seeking a Principal Scientist in ADME-PK to enhance drug delivery to muscle and CNS tissues. The successful candidate will design preclinical studies, author regulatory documents, and collaborate across various teams. Candidates should possess a PhD in a relevant field and over 6 years of industry experience, with expertise in pharmacokinetics and drug metabolism. This role offers a competitive salary in the range of $159,000 to $195,000 USD depending on experience.
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$159k-195k yearly 5d ago
Sr. Principal Scientist
The University of Texas Md Anderson Cancer Center 4.3
Senior scientist job in Boston, MA
The role will be responsible for all operations involved with routine manufacturing and quality control testing of radiopharmaceuticals produced in Aktis' GMP laboratory (Boston, MA), including but not limited to the list below.
This role will report to the Director of Clinical Trial Manufacturing.
Salary Range: $136,800.00 To $189,200.00 Annually
Responsibilities
Manual and automated production of radiopharmaceuticals in a GMP facility
QC testing of radiopharmaceuticals
Execution and upkeep of the facilities' environmental monitoring program
Accurate and timely preparation and completion of manufacturing and Quality control records (Batch Records, Forms, Logbooks, etc.)
Process/analytical method validation for clinical manufacturing
Operation and maintenance of equipment in the GMP facility
Preparation of products for shipment to other sites
Drafting, reviewing and updating GMP documentation including SOPs
Upkeep and maintenance of inventory in the GMP Facility
Maintenance of the GMP facility including assisting with radioactive waste stream management
Perform contamination wipe tests and surveys
Performing and maintenance of the facilities' environmental monitoring program
Leading manufacturing process and analytical method qualification activities
Contribute to writing CMC sections for submission to regulatory agencies
Maintain KPI and internal reports
Supporting external tech transfer activities
Required Skills
Proficient with aseptic operations and environmental monitoring
Proficient with QC methodologies (HPLC, GC, MS, Gamma Spec, etc.)
Proficient with assembly and interpretation of analytical data
Expertise with troubleshooting analytical and production equipment
High attention to detail and organizational skills to enable working in a fast-paced environment
Ability to work in an ISO7 environment with full gowning
Adhere to stringent cleanroom protocols and maintain a high level of hygiene
Perform precise aseptic manipulations in a restrictive environment
Awareness of FDA and EU GMP requirements
Ability to lift 60lbs
Expertise with GMP radiopharmaceutical manufacturing and quality control
Minimum, B.Sc. with 10+ years or M.Sc. with 7+ years of experience in the pharma industry or equivalent research experience
Comprehensive knowledge of GMP manufacturing and quality control workflows
Excellent verbal, written, and organizational skills
Strong desire to be part of a mission‐oriented company leading transformative change for patients
Proven demonstration of transparent communication and fostering open and diverse debate
Ability to work with agility and manage ambiguity
Personifies positive energy and exemplifies respect
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$136.8k-189.2k yearly 5d ago
Principal Scientist - Physics (REQ 298)
Applied Physical Sciences Corp 4.1
Senior scientist job in Concord, MA
Applied Physical Sciences (APS) is looking for a highly motivated Physical Scientist to join the Concord, MA team in a part-time, on-call (PTOC) position. Successful candidates will have a PhD in theoretical physics, expertise in inverse theory or tomography, and will support the development of state-of-the-art technologies for tomographic imaging with irregular experiment apertures, with a special emphasis on exploitation of high energy X-rays.
APS works on exciting, technically challenging, cutting-edge technologies that will expose candidates to a wide variety of multidisciplinary fields, providing a stimulating environment with considerable opportunity for collegial interaction. At APS you will work in a small company environment where technical excellence is rewarded and an entrepreneurial spirit is encouraged, and you will have the chance to work directly with colleagues and customers that value innovation and creativity.
Responsibilities
Theoretical modeling of x-ray interaction physics, development of X-ray inversion paradigms for highly challenging experiment scenarios, rigorous characterization of the fundamental information limits of X-ray imaging.
Software implementation of processing and modeling techniques, numerical execution of synthetic inversion experiments, display and quantification of model uncertainty
Required Attributes and Skills
PhD in theoretical physics, and expertise in modeling and inversion of X-ray data
Subject matter expertise in one or more of the following: advanced numerical optimization, statistical methods, experiment design optimization, GPU-based computing
Extensive experience with computational methods and programming for modeling physical phenomena and processing of real data e.g., Matlab, Python, PyTorch, or Fortran
Exceptional communication skills (written and oral) for technical documentation and reviews with customers
Desired Attributes and Skills
Professional experience of 10+ years in DoD or related industry, a strong publication history in refereed technical journals, and a track record of successful performance on research programs under DARPA, IARPA, NAVSEA or ONR sponsorship is preferred.
Experience as principal investigator working on advanced R&D programs
Demonstrated technical leadership in modeling and simulation
Expertise in one or more of the following: mathematical physics, model-based iterative methods for x-ray tomography, Monte Carlo radiative transport methods for Bremsstrahlung modeling, advanced numerical optimization techniques involving both continuous and discrete variables, regularization methods, uncertainty quantification using the Fisher Information Matrix and the Cramer-Rao Bound, and multi-objective optimization.
Experience presenting talks at technical conferences
APS, a wholly owned subsidiary of the General Dynamics Corporation, offers a small company environment including competitive salary, excellent benefits, and comfortable working conditions. This is a part-time on-call position open in the Concord, MA office. Candidates must possess or be able to obtain a Top Secret DOD security clearance.
Qualified applicants are invited to submit a resume and application online at **************** fax them to ************, Attn: Human Resources, or mail to the company address. Please reference the requisition number and title of the position in the subject line of your submission.
Equal Opportunity Employer/M/F/Disability/Protected Vet
Invitation to Self-Identify
In keeping with our commitment to Equal Employment Opportunity (EEO), Applied Physical Sciences invites all applicants to self-identify pre-offer as a protected veteran and/or an individual with a disability.
Invitation to Self-Identify as Protected Veteran
Online Form
Invitation to Voluntary Self-Identification of Disability
Online Form
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$90k-127k yearly est. 4d ago
Principal Machine Learning Scientist, Foundation Models, AI for Drug Discovery
Genentech 4.5
Senior scientist job in Boston, MA
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximizing these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity
At Roche's AI for Drug Discovery (AIDD) group (Prescient Design), we are revolutionizing drug discovery with cutting‑edge machine learning (ML) techniques. We are seeking talented scientists with a research background in ML, a passion for independent research and technical problem‑solving, and a proven ability to develop and implement ideas from research. AIDD's Foundation Model team is seeking an exceptional Principal ML Scientist to develop the next generation of multimodal foundation models & LLMs and enable the next generation of AI/ML‑powered drug discovery applications as part of our Lab‑in‑the‑Loop. We are looking for someone who is not only passionate about technical problem‑solving but also has a proven research track record. The ideal candidate should have extensive experience in both the science and engineering of ML, and be able to foster a culture of innovation, collaboration, and excellence across the broader Roche organization. The group provides a dynamic and challenging environment for multidisciplinary research, including access to heterogeneous data sources, close links to top academic institutions around the world, as well as collaborations with internal Genentech and Roche teams.
In this role, you will:
Participate in cutting‑edge research in machine learning with applications to drug discovery and development.
You will collaborate closely with cross‑functional teams across Genentech and Roche to solve complex problems in multimodal and representation learning.
You will provide technical leadership in machine learning, both in research and engineering, driving and shaping research directions for foundation model applications to drug discovery across Genentech and Roche.
You will be expected to contribute to and drive publications, and present results at internal and external scientific conferences.
Who You Are
Ph.D. in Computer Science, Statistics, Applied Mathematics, Physics, related technical field, or equivalent practical experience.
At least 2-7 years of relevant work experience.
Strong publication record and experience contributing to research communities, including conferences like NeurIPS, ICML, ICLR, AISTATS, UAI, CVPR, ACL, etc., including at least one first‑author publication or equivalent.
Strong programming skills in languages like Python, C++, Java, or Go.
Extensive experience with deep learning frameworks like PyTorch.
Preferred
Intense curiosity about the biology of disease, drug discovery, and development
Passion to contribute to scientific and computational efforts.
Relocation benefits are available for this job posting
The expected salary range for this position, based on the primary location of New York City, is $185,600 - 344,600 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job‑related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
#ComputationCoE
#tech4lifeComputationalScience
#tech4lifeAI
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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$112k-145k yearly est. 2d ago
Phosphoramidite Scientist - Process Research & Development
Veranova
Senior scientist job in Devens, MA
Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
The Scientist role within the Chemical Development group will focus on the synthesis, process development, and analytical strategy for protected phosphoramidite precursors used in therapeutic oligonucleotide API manufacturing. This position is key to building Veranova's commercial capability in producing high-quality oligonucleotide building blocks. The ideal candidate will have strong expertise in phosphoramidite chemistry, including impurity profiling and customer-specific requirements. This role will also collaborate closely with the Analytical Team to establish robust characterization and control strategies that ensure exceptional product quality.
Core Responsibilities:
Develop and optimize synthetic routes for protected Phosphoramidite subunits used in therapeutic oligonucleotide API synthesis.
Identify and mitigate side reactions commonly associated with Phosphoramidite chemistry.
Define and implement specifications aligned with customer expectations for commercial-grade oligonucleotide precursors.
Provide expert guidance to the Analytical Team on the selection and application of appropriate analytical methods for product and impurity characterization, based on prior experience and industry standards.
Collaborate with cross-functional teams including Analytical Development, Quality, and Manufacturing to ensure successful scale-up and tech transfer.
Prepare technical documentation including batch records, specifications, and development reports in accordance with SOPs and cGMP guidelines.
Present scientific findings and project updates to internal stakeholders and external customers.
Support the establishment of quality and regulatory standards for commercial production of oligonucleotide precursors.
Contribute to project planning, budgeting, and timeline management for precursor development programs.
Other duties as assigned .
Qualifications:
Required
BS in Organic Chemistry or equivalent with 3-5 years related experience in a pharmaceutical industry, or
MS in Organic Chemistry or equivalent with 0-2 years related experience in the pharmaceutical industry.
Ability to read, analyze, and interpret English-language chemical periodicals, scientific journals, and regulatory documents.
Experience with organic synthesis and process development
Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS.
Experience in establishing integrated plans with defined resources and tasks.
Ability to write clear and concise technical reports.
Good understanding of Microsoft Office and statistical software.
Demonstrate ability to exercise good judgment and make decisions quickly.
Good written and verbal communication skills.
Ability to work independently and in a team environment.
Salary Range : $110,000 - $120,000 annual base salary
Our Commitment:
Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
$110k-120k yearly 2d ago
Analytical Scientist
Nextcea, Inc.
Senior scientist job in Woburn, MA
Nextcea Inc. is a pharmaceutical services company that focuses on assessing drug efficacy and safety during late-stage drug development and clinical trials. We are currently seeking full-time Analytical Chemists to join our team.
Qualified candidates will actively participate in LC-MS biomarker analysis at Nextcea. Successful applicants should hold an MS or PhD in Analytical Chemistry or a related field, along with relevant laboratory experience. While experience with LC-MS is preferred, it is not mandatory.
We are seeking self-motivated candidates who are excellent team players and can effectively contribute to established laboratory procedures and protocols. Candidates should be able to work independently, demonstrate flexibility, and adapt to the challenges of pharmaceutical biomarker projects.
At Nextcea, we value diversity and inclusion. We offer competitive compensation and benefits, including medical, vision, dental, and 401(k) plans, to all employees, regardless of their background or identity.
Applicants are required to submit their resumes online via LinkedIn.
$77k-109k yearly est. 2d ago
Downstream Scientist - Top Pharmaceutical Company
Insight Global
Senior scientist job in Andover, MA
We are looking for a Downstream Scientist to join our client's Manufacturing Sciences and Technology (MSAT) organization based in Andover, MA. The MSAT downstream purification team supports purification process development and optimization for commercial processes and next generation process development.
This person will be expected to execute and qualify various downstream purification unit operations, ensure the proper and timely execution of purification processing at both pilot and/or bench scale of various biologics using a variety of unit operations, such, depth filtration, TFF (UF/DF), and chromatography.
Experience with process development and characterization for a polysaccharide based programs and/or second-generation process development of biologics using various purification techniques.
Independently plan, design, and execute downstream experiments to enable technology transfer of polysaccharide programs and/or second-generation purification processes to receiving units.
Direct hands on experience with operation and maintenance of downstream equipment (AKTAs, Repligen TFF, etc.. and associated analytical tools (SoloVPE and Stunner etc..)
Proficient with data analysis, technical writing, reporting, and presenting to internal teams.
Support investigational studies and purification process troubleshooting as needed.
Drive a culture of safety, continuous improvement and operational excellence initiatives within department.
Independently plan, prepare, execute, and conclude critical material production campaigns.
Emphasize strong communication, teamwork, growth mindset and cross functional collaboration with other project teams as needed
EDUCATION AND EXPERIENCE
Bachelor's degree or higher in a relevant discipline with at least 3 years of applicable bioprocess experience.
Experience with process purification of biomolecules (mAbs, vaccines, etc…) from harvest to drug substance
Familiarly working in GxP cross matrix organizations
Lab-scale purification process development and troubleshooting experience with standard downstream equipment (e.g. AKTAs, Repligen TFF, etc…)
Direct hands on experience and knowledge of templated processes such as mAbs, pDNA, mRNA etc…
Proficient experience with data analysis tools such as Minitab, JMP, etc…
Working knowledge of PAT applications development and implementation from bench scale to pilot
Experience with HTS instrumentation for protein purification and process development
Working knowledge of GxP/ICH/Quality compliance systems of the biopharmaceutical industry
$70k-104k yearly est. 20h ago
Research Associate/Sr. Research Associate, Discovery Biology/Drug Discovery
IOCB Boston
Senior scientist job in Cambridge, MA
Job Title: Research Associate/Sr. Research Associate, Discovery Biology/Drug Discovery
Institute: Institute of Organic Chemistry and Biochemistry (IOCB) Boston
Position Type: Full-Time, In-Person / Laboratory-Based (no remote work)
Classification: Exempt -- This position is classified as exempt and involves advanced professional duties requiring specialized knowledge in a scientific field.
About the Position
The Institute of Organic Chemistry and Biochemistry (IOCB) is expanding its presence in the Boston area and is seeking a Research Associate or Associate Scientist to join our Drug Discovery team. This role offers a unique opportunity to contribute to both hypothesis-driven basic research and early pre-clinical drug discovery efforts.
The ideal candidate is highly hands-on and intellectually curious, with strong experience in cell biology, molecular biology, and biochemistry, and an interest in building robust assays and generating high-quality data to support target validation and drug discovery.
Key Responsibilities
Experimental Design & Execution
Under the guidance of the Head of Drug Discovery, independently plan and execute experiments, analyze data, and clearly communicate results in team meetings and to external collaborators.
Maintain rigorous documentation and reproducibility standards (e.g., controls, repeatability, robust assay performance).
Collaborative Drug Discovery Research
Partner closely with interdisciplinary colleagues (proteomics, protein science, computational, external academic collaborators) to advance target validation, mechanism-of-action studies, and early discovery programs.
Contribute to project planning, experimental prioritization, and interpretation of results in a drug-discovery context.
Assay & Method Development
Develop, optimize, and validate cellular and biochemical assays (e.g., potency, selectivity, pathway readouts).
Support screening workflows and follow-up characterization of hits.
Leverage and/or help expand capabilities in discovery biology, proteomics, biophysics, and protein science as needed.
Required Qualifications
Education & Experience
Research Associate: Bachelor's degree with relevant research experience
Sr. Research Associate: Master's degree with relevant research experience
Core Competencies
Strong hands-on experimental ability in one or more of: cell biology, molecular biology, biochemistry, biophysics
Self-directed, organized, and motivated; able to work effectively both independently and in a collaborative team environment
Strong written and verbal communication skills with attention to detail and data integrity
Technical Expertise (or Strong Willingness to Learn)
Drug Discovery Biology: biochemical and/or cell-based assay development; screening support; basic screening data analysis; data organization and tracking
Molecular Biology: cloning, mutagenesis, PCR/Gibson, RT-qPCR, Western blotting; experience with CRISPR/Cas9 a plus
Software & Data: proficiency with GraphPad Prism and Microsoft Office (Word/Excel/PowerPoint); familiarity with Python for data analysis is a plus
Preferred Qualifications
Prior experience in an academic or industry drug discovery environment (target validation, assay development, screening, hit follow-up)
Experience working with compound libraries and follow-up screening logistics
Demonstrated interest in translational science and using modern tools/technologies to answer biological questions
Salary Range:
Research Associate $69,000 - 71,000 USD per year, Sr. Research Associate $75,000 - 90,000 USD per year.
The salary range listed represents IOCB Boston's good faith estimate for this position and is based on factors including, but not limited to, education, experience, skills, internal equity, and market data. Final compensation will be commensurate with qualifications and experience.
Benefits: Competitive benefits package including employer-subsidized medical, dental, and vision insurance; transportation contribution; generous paid time off; and company-paid Accidental Death & Dismemberment (AD&D), Short-Term Disability (STD), Long-Term Disability (LTD), and life insurance.
Work Authorization/Visa Sponsorship: IOCB Boston does not sponsor employment-based visas for this position. Candidates must be legally authorized to work in the United States at the time of hire and must maintain work authorization throughout the duration of employment without the need for current or future employer sponsorship. Employment eligibility will be verified in accordance with federal law. IOCB Boston participates in the federal E-Verify program. Employment offers are contingent upon the successful completion of a background check conducted in accordance with applicable federal and Massachusetts laws
Why Join Us
You'll join a collaborative and ambitious team working at the interface of basic biology and early drug discovery. This role provides meaningful ownership of experiments and methods, opportunities to work across disciplines, and the chance to contribute to high-impact science in a fast-moving, supportive environment.
TO APPLY:
Please email ********************************* to express your interest. Include your most recent curriculum vitae or resume as well as a cover letter that describes your interest in this position.
Direct applicants only. IOCB Boston does not accept unsolicited resumes from recruitment or employment agencies.
Equal Employment Opportunity Statement
IOCB Boston is an Equal Opportunity/Affirmative Action Employer. We are committed to providing equal employment opportunities to all qualified applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity or expression, age, national origin, disability, protected veteran status, genetic information, or any other status protected by applicable law.
$75k-90k yearly 3d ago
Translational PET Imaging Scientist - Clinical Trials Lead
MSD Malaysia
Senior scientist job in Boston, MA
A prominent pharmaceutical company is seeking a Translational PET Imaging Scientist to lead clinical implementation of novel PET tracers in oncology studies. Responsibilities include developing imaging strategies, overseeing studies, and managing regulatory submissions. The ideal candidate should hold a Ph.D. and have extensive experience in advancing PET tracers into clinical trials with proven project leadership. This role offers a hybrid work model and a competitive salary range.
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$65k-101k yearly est. 2d ago
Join a research study evaluating potential new investigational treatments for Depression
Haltha
Senior scientist job in Boston, MA
Up To $1,000 Paid Depression Study! Those who Currently Experience At Least TWO Symptoms of Depression And the Current Depressive Episode Started More Than 4 Weeks Ago May Qualify For The Study!
$85k-130k yearly est. 7d ago
Medical Laboratory Scientist, Senior I - Immunology
Brigham and Women's Hospital 4.6
Senior scientist job in Boston, MA
Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process.
Job Summary
Summary
As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases.
The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management.
Does this position require patient care?
No
Essential Functions
After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must:
Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping.
Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples.
Adhere to quality control policies and document all QC activities, calibrations, and maintenance.
Follow established corrective action procedures when test systems fall outside acceptable performance standards.
Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director.
Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495.
Qualifications
Education
Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required
Experience
lab experience 4 years required
Knowledge, Skills and Abilities
* The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action.
* Demonstrates advanced level of analytical skills and judgement.
* Must have understanding of computer technology and its application to analytical procedures and quality control.
* Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques.
* Must have the ability to work independently, evaluate situations and act appropriately.
* Ability to multitask in a fast-paced environment.
* Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified.
* Must be able to perform as a team member.
* Excellent interpersonal skills.
* Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients.
* Advanced knowledge of federal, state and accreditation requirements.
Additional Job Details (if applicable)
Physical RequirementsStanding Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%)
Remote Type
Onsite
Work Location
221 Longwood Avenue
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
Pay Range
$33.46 - $48.66/Hourly
Grade
7
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
$33.5-48.7 hourly Auto-Apply 31d ago
Principal Scientist, ADME-PK
Dyne Tx
Senior scientist job in Waltham, MA
Our commitment to people with neuromuscular diseases
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more ************************* and follow us on X, LinkedIn and Facebook.
Role Summary:
The Principal S cientist , ADME-PK in Preclinical Development (PCD) department utilize s their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance Dyne 's efforts surrounding delivery of therapeutic payloads to muscle and CNS tissues with the FORCE platform .
This role is based in Waltham, MA.
Primary Responsibilities Include:
Design and execute internal/external preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of Dyne's drug candidates
Represent PCD as the ADME-PK subject matter expert on discovery and program teams
Partner with and support Research, Toxicology, Translational Biomarkers, Clinical, Regulatory, Project Management and other Dyne departments
Collaborate with Clinical Pharmacology/Pharmacometrics to develop quantitative tools to translate PK/PD relationship from preclinical to clinical
Author high quality Regulatory documents including INDs, CTAs, and NDA/BLA filings.
Prepare strategic and science-based ADME strategies that meet regulatory requirements and program goals
Facilitate strategic scientific communication via meetings, abstracts and manuscripts
Education and Skill Requirements:
PhD in Pharmacokinetics, Pharmacology, Pharmaceutics, Biomedical Sciences or other relevant field with >6 years (MS with >8 years, BS with >12 years) of experience in the biopharmaceutical industry, with evidence of drug development experience
Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamics and bioanalytical principles
F amiliarity with regulatory submission including FIH dosing strategy is highly desirable
Proficient in using WinNonlin or other pharmacokinetic software
Excellent communication (verbal and written) and presentation skills, as well as interpersonal skills and the ability to represent PCD in a team environment
Experience with PK characterization of protein therapeutics or antibody-drug conjugates (ADCs) is desired
#LI-Onsite
MA Pay Range
$159,000 - $195,000 USD
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
#J-18808-Ljbffr
$159k-195k yearly 5d ago
Senior Principal Scientist, GMP Radiopharmaceuticals
The University of Texas Md Anderson Cancer Center 4.3
Senior scientist job in Boston, MA
A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care.
#J-18808-Ljbffr
$98k-137k yearly est. 5d ago
Lead ML Scientist, Foundation Models for Drug Discovery
Genentech 4.5
Senior scientist job in Boston, MA
A leading biotechnology company is seeking a Principal ML Scientist to innovate in drug discovery using machine learning techniques. This role involves conducting advanced research and providing technical leadership in the application of foundation models for drug discovery. Ideal candidates will possess a Ph.D. in a relevant field, have a strong publication record, and experience in programming with languages like Python and C++. The company offers competitive compensation and relocation benefits.
#J-18808-Ljbffr
$104k-136k yearly est. 2d ago
Scientist - Process Research & Development
Veranova
Senior scientist job in Devens, MA
Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
The Process R&D Scientist plays a key role in developing and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs). This position conducts small- to large-scale chemical reactions and generates high-quality data that supports project decision-making and innovation. Working under the guidance of technical leads, the role contributes to delivering projects on time, on spec, and within budget. It's an excellent opportunity to deepen expertise while supporting impactful pharmaceutical development.
Core Responsibilities:
Delivers experimental output with high scientific integrity, meeting targets, timelines, and quality expectations with guidance.
Exhibits strong safety awareness, conducts laboratory and operational activities safely, and maintains accountability for safe behavior in the work environment.
Maintains technical equipment and related services to ensure proper functionality.
Acts on feedback and demonstrates a continuous commitment to learning and professional development.
Leads technical and operational areas and supports troubleshooting for complex scientific issues with minimal guidance.
Shares knowledge, skills, and experience effectively with internal and external stakeholders; may lead focused projects as a key contact.
Keeps accurate, legible, and complete records of all experiments, observations, and equipment use.
Writes high-quality reports and delivers presentations to customers and management with some guidance, aligned with project milestones.
Contributes to maintaining strong customer relationships and identifies new commercial opportunities.
Actively supports the technical development of the department and the broader organization.
Ensures all documentation meets Veranova standards; supports audit readiness and participates in regulatory and customer audits as needed; reports near misses and safety incidents per company procedures; and ensures all work complies with applicable state and federal regulations, including GMP, DEA, and FDA requirements.
Adheres to all EHS policies and procedures; demonstrates strong technical and procedural proficiency in applying EHS standards; supports EHS audit readiness and participates in audits; reports and cooperates fully in investigations of near misses and incidents; and upholds Veranova's EHS commitments by integrating ISO 14001, OHSAS 18001, and Sustainability 2025 principles into daily work.
Performs additional duties within the employee's skills and abilities as reasonably assigned.
Qualifications:
Required
PhD degree (or equivalent experience) in a chemistry related discipline.
Proficiency with relevant lab and analytical techniques.
Previous industry experience in relevant areas.
Proficiency with relevant analytical techniques within an industry environment.
Ability to write clear and concise technical reports.
Good understanding of Microsoft Office and other relevant technical software platforms.
Skilled in written and spoken communication and proven ability to effectively interact with management.
Demonstrates good judgment, quick decision-making skills, and the ability to work independently and in a team environment.
Special Factors
Must be able to stand, walk, and manually operate objects, tools, or controls; reach with hands or arms; and climb, balance, stoop, kneel, or crouch when necessary for the job activity.
Must be able to lift and/or move up to 50 pounds.
Specific vision abilities include near, distance, peripheral, color perception, and the ability to adjust focus.
May regularly work with moving mechanical parts and may work with toxic or caustic chemicals.
May work in humid areas with low or high temperatures.
May be required to work with a respirator or operate with full-body Tyvek suits and supplied air or PAPR.
Salary Range : $105,000 - $120,000 annual base salary
Our Commitment:
Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
$105k-120k yearly 2d ago
Join a research study evaluating potential new investigational treatments for Depression
Haltha
Senior scientist job in Manchester, NH
Up To $1,000 Paid Depression Study! Those who Currently Experience At Least TWO Symptoms of Depression And the Current Depressive Episode Started More Than 4 Weeks Ago May Qualify For The Study!
$63k-96k yearly est. 7d ago
Analytical Scientist - Anti Body Drug Conjugates
Veranova
Senior scientist job in Devens, MA
Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
We are seeking a highly motivated and skilled Analytical Scientist to join our Analytical team in New England. The successful candidate will have expertise in LCMS (Liquid Chromatography-Mass Spectrometry) based characterization of complex bioconjugates, with a strong understanding of ADC structure and stability.
Core Responsibilities:
Exercise technical judgment in the planning, implementation, and analysis of experiments related to method development, validation, reference standard creation and qualification, forced degradation, product characterization, and compatibility studies in accordance with pertinent ICH regulatory guidelines.
Develop and optimize LCMS methods for qualitative and quantitative analysis of ADCs. Develop and validate quantitative LCMS methods such as:
Drug-to-Antibody Ratio (DAR) determination.
Payload quantification (free and conjugated forms).
Linker stability and degradation profiling.
Site-specific conjugation analysis.
Perform intact mass analysis, peptide mapping, drug-to-antibody ratio (DAR) determination, and payload identification.
Characterize ADCs for critical quality attributes including conjugation sites, linker stability, and degradation products.
Author test methods, protocols, reports, and regulatory documents as needed.
Provide support for development and cGMP manufacturing campaigns, ensuring compliance with regulatory requirements and documentation standards - including both in-process and release samples.
Adhere to safety and quality standards.
Communicate technical findings and results to both internal and external stakeholders, including clients and regulatory bodies.
Collaborate with chemistry development scientists, quality control and regulatory affairs teams to ensure successful project delivery.
Mentor and develop scientific staff. Ensure continued technical and professional growth of department members, encourage efforts towards excellence and knowledge sharing.
Possess strong communication (oral, written), organizational, and leadership skills.
Maintain and troubleshoot LCMS instrumentation (e.g., Orbitrap, Q-TOF, Triple Quad).
Qualifications:
Required
Ph.D., M.S., or B.S. in Analytical Chemistry, Biochemistry, Chemistry, Chemical/Biomedical Engineering, or other related scientific discipline.
Relevant experience in analytical method development, validation and characterization of bioconjugates. (PhD with 4+ years, MS with 6+ years, BS with 8 + years of experience.
4+ years of hands-on experience in LCMS analysis of biologics, preferably ADCs.
Strong knowledge of protein chemistry, conjugation technologies, and biotherapeutic development.
Proficiency in any of the software tools for MS data analysis (e.g., Xcalibur, MassHunter, Skyline, Biopharma Finder).
Well organized with good problem-solving skills, a high level of attention to detail and have a passion for delivering high quality data in a fast-paced environment.
Preferred
Experience with regulatory submissions and GMP/GLP environments.
Experience with various techniques used in the characterization of ADC's such as capillary electrophoresis (CE-SDS) for ADC purity and size analysis, hydrophobic interaction chromatography (HIC) for DAR profiling, size-exclusion chromatography (SEC) for aggregation and stability studies, UV-Vis spectroscopy and fluorescence-based assays for payload quantification, and immunoassays (ELISA, ECL) for antibody detection.
Salary Range: $100,000 - $120,000 annual base salary
Our Commitment:
Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
$100k-120k yearly 2d ago
Join a research study evaluating potential new investigational treatments for Depression
Haltha
Senior scientist job in Seabrook Beach, NH
Up To $1,000 Paid Depression Study! Those who Currently Experience At Least TWO Symptoms of Depression And the Current Depressive Episode Started More Than 4 Weeks Ago May Qualify For The Study!
How much does a senior scientist earn in Everett, MA?
The average senior scientist in Everett, MA earns between $75,000 and $137,000 annually. This compares to the national average senior scientist range of $74,000 to $153,000.
Average senior scientist salary in Everett, MA
$101,000
What are the biggest employers of Senior Scientists in Everett, MA?
The biggest employers of Senior Scientists in Everett, MA are: