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Senior scientist vs principal scientist

The differences between senior scientists and principal scientists can be seen in a few details. Each job has different responsibilities and duties. It typically takes 2-4 years to become both a senior scientist and a principal scientist. Additionally, a principal scientist has an average salary of $119,982, which is higher than the $106,672 average annual salary of a senior scientist.

The top three skills for a senior scientist include patients, data analysis and molecular biology. The most important skills for a principal scientist are oncology, data analysis, and drug discovery.

Senior scientist vs principal scientist overview

Senior ScientistPrincipal Scientist
Yearly salary$106,672$119,982
Hourly rate$51.28$57.68
Growth rate17%17%
Number of jobs49,71280,899
Job satisfaction--
Most common degreeBachelor's Degree, 51%Bachelor's Degree, 51%
Average age4141
Years of experience44

What does a senior scientist do?

A senior scientist is usually in charge of overseeing experiments and evaluating junior scientists' performance, especially in laboratory settings. Moreover, it is also their responsibility to assess every progress report to ensure it's accuracy and validity. As a senior scientist in the field, it is essential to lead and encourage fellow scientists in their joint pursuit for scientific innovations, all while adhering to the laboratory's standards and policies.

What does a principal scientist do?

A Principal Scientist is focused on leading scientific teams and conducting research. They ensure that their teams have the resources to properly perform research tasks.

Senior scientist vs principal scientist salary

Senior scientists and principal scientists have different pay scales, as shown below.

Senior ScientistPrincipal Scientist
Average salary$106,672$119,982
Salary rangeBetween $74,000 And $153,000Between $84,000 And $169,000
Highest paying CityRedwood City, CASan Francisco, CA
Highest paying stateCaliforniaCalifornia
Best paying companyBill & Melinda Gates FoundationPayPal
Best paying industryTelecommunicationFinance

Differences between senior scientist and principal scientist education

There are a few differences between a senior scientist and a principal scientist in terms of educational background:

Senior ScientistPrincipal Scientist
Most common degreeBachelor's Degree, 51%Bachelor's Degree, 51%
Most common majorChemistryChemistry
Most common collegeDuke UniversityDuke University

Senior scientist vs principal scientist demographics

Here are the differences between senior scientists' and principal scientists' demographics:

Senior ScientistPrincipal Scientist
Average age4141
Gender ratioMale, 70.1% Female, 29.9%Male, 76.8% Female, 23.2%
Race ratioBlack or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.5% Asian, 26.9% White, 53.2% American Indian and Alaska Native, 0.1%Black or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.6% Asian, 26.4% White, 53.4% American Indian and Alaska Native, 0.1%
LGBT Percentage8%8%

Differences between senior scientist and principal scientist duties and responsibilities

Senior scientist example responsibilities.

  • Lead the development and implementation of new technology for use in NMR applications.
  • Strategize and manage the PK/PD program with internal collaborations including chemistry, DMPK, formulation and toxicology.
  • Lead a team and develop a 24-channel GC parallel separation system for high throughput screening of catalysts.
  • Lead a team of 11 direct reports and 35 indirect reports to solve development problems for multicapillary electrophoresis instruments.
  • Influence and impact others through building and maintaining strong networks that are leverage to obtain critical information and accomplish objectives.
  • Manage collaborations with external CROs.
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Principal scientist example responsibilities.

  • Manage pediatric dose development project, technology transfer project and alternate API supplier qualification project on budget and on schedule
  • Provide development of and line support for assign immunoassay reagents, calibrators and controls.
  • Transfer controls to manufacturing for product launch and include all require studies, testing and documentation under GMP guidelines.
  • Maintain several lab documents for ISO certification.
  • Understand drug metabolism and pharmacokinetics and design stable molecules.
  • Image visualization and manipulation of background plates for animation and post-processing.
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Senior scientist vs principal scientist skills

Common senior scientist skills
  • Patients, 11%
  • Data Analysis, 6%
  • Molecular Biology, 3%
  • Research Projects, 3%
  • C++, 3%
  • Java, 3%
Common principal scientist skills
  • Oncology, 7%
  • Data Analysis, 6%
  • Drug Discovery, 5%
  • GMP, 3%
  • Experimental Design, 3%
  • Clinical Trials, 3%

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