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Cas Financial Construction company history timeline

1907

CAS is rooted in the publication Chemical AbstractsTM (CA), a journal of the American Chemical Society first published in 1907.

1974

26.Jaenisch R, Mintz B (1974) Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Proc Natl Acad Sci USA 71(4):1250–1254CAS Article Google Scholar

1977

25.Itakura K, Hirose T, Crea R, Riggs AD, Heyneker HL, Bolivar F, Boyer HW (1977) Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.

1979

21.Goeddel DV, Kleid DG, Bolivar F, Heyneker HL, Yansura DG, Crea R, Riggs AD (1979) Expression in Escherichia coli of chemically synthesized genes for human insulin.

1987

CRISPRs were first identified in E. coli in 1987 by a Japanese scientist, Yoshizumi Ishino, and his team, who accidentally cloned an unusual series of repeated sequences interspersed with spacer sequences while analyzing a gene responsible for the conversion of alkaline phosphatase.

24.Ishino Y, Shinagawa H, Makino K, Amemura M, Nakata A (1987) Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product.

2002

27.Jansen R, Embden J, Gaastra W, Schouls L (2002) Identification of genes that are associated with DNA repeats in prokaryotes.

2005

4.Bolotin A, Quinquis B, Sorokin A, Ehrlich SD (2005) Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin.

2007

Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, Romero DA, Horvath P. 2007.

2008

Brouns SJ, Jore MM, Lundgren M, Westr ER, Slijkhuis RJ, Snijders AP, Van Der Oost J (2008) Small CRISPR RNAs guide antiviral defense in prokaryotes.

2010

23.Horvath P, Barrangou R (2010) CRISPR/Cas, the immune system of bacteria and archaea.

49.Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD (2010) Genome editing with engineered zinc finger nucleases.

2011

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA et al (2011) CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471(7340):602–607. https://doi.org/10.1038/nature09886

8.Carroll D (2011) Genome engineering with zinc-finger nucleases.

2012

The use of CRISPR-Cas9 to edit genes was thrust into the spotlight in 2012 when George Church, Jennifer Doudna, Emmanuelle Charpentier, and Feng Zhang harnessed it as a tool to modify targeted regions of genomes.

20.Gasiunas G, Barrangou R, Horvath P, Siksnys V (2012) Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.

2013

In 2013, Cong et al. and Mali et al. described CRISPR-based genome editing in mammalian cell culture.

Bondy-Denomy J, Pawluk A, Maxwell KL, Davidson AR. 2013.

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. 2013.

2014

Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK. 2014.

Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. 2014.

Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelson T, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. 2014.

2015

Bondy-Denomy J, Garcia B, Strum S, Du M, Rollins MF, Hidalgo-Reyes Y, Wiedenheft B, Maxwell KL, Davidson AR. 2015.

2016

41.Rodriguez E (2016) Ethical issues in genome editing using CRISPR/Cas9 System.

Kleinstiver BP, Pattanayak V, Prew MS, Tsai SQ, Nguyen NT, Zheng Z, Joung JK. 2016.

Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. 2016.

2017

50.Umenhoffer K, Draskovits G, Nyerges Á, Karcagi I, Bogos B, Tímár E et al (2017) Genome-wide abolishment of mobile genetic elements using genome shuffling and CRISPR/Cas-assisted MAGE allows the efficient stabilization of a bacterial chassis.

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA. 2017.

Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. 2017.

2018

2.Barnett P (2018) Transcription activator like effector nucleases (TALENs): a new, important, and versatile gene editing technique with a growing literature.

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