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1986: Arthur Zinn, MD, Douglas Kerr, MD, Charles Hoppel, MD, published the first description and detailed characterization of a defect (in the enzyme fumarase) in the famous pathway required for energy metabolism, the Krebs cycle.
1987: Jerrold Ellner, MD, and Frederick Robbins, MD, established a memorandum of understanding with Makerere University in Uganda, linking Cleveland and Kampala AIDS research and care efforts.
Northeastern Ohio General Hospital closes its doors in 1988 and later reopens as part of the Lake Hospital System.
1988: Herbert Meltzer, MD, conducted the first human trials of clozapine and established it as an effective medication for treatment-resistant schizophrenic patients.
1988: The University Hospitals Health System formed.
1989: Joseph Calabrese, MD, in collaboration with researchers at Case Western Reserve University, launched groundbreaking studies that show the effectiveness of anticonvulsants and atypical antipsychotics in treating bipolar disorder.
1989: Anthony Maniglia, MD, Chair, and Laura Cozzi, MD, established a technique for safe outpatient tonsillectomy and adenoidectomy, using bismuth to control bleeding.
1990: Anthony Maniglia, MD, was awarded the first of five patents leading to technology for developing the totally implantable cochlear implant.
1993: UH began merging with various community hospitals in Geauga County, Bedford, Conneaut, Richmond Heights and Geneva to create a regional health care system.
1994: Alfred and Norma Lerner Tower & the Samuel Mather Pavilion opened on the University Circle campus through a gift of $10 million.
1994: Susan Shurin, MD, performed the first umbilical cord transplant to treat childhood leukemia, using cord blood stem cells from the patient’s newborn sister.
1996: Pierluigi Gambetti, MD, developed the first classification of sporadic prion diseases, now used worldwide in diagnosing this class of dementias, caused by mutation of the prion protein gene.
1997: University Hospitals partnered with Southwest General Health Center in Middleburg Heights.
In 1999, Ohio State surgeons were the first in North America to perform a robotic-assisted heart procedure with the Da Vinci Surgical System.
In 2000, Ohio State opened the Dorothy M. Davis Heart and Lung Research Institute, helping to advance translational research by connecting the work of basic scientists with clinical scientists.
2000: Raymond Onders, MD, and colleagues developed an innovative diaphragmatic pacing system (DPS) that has since greatly improved the quality of life for paralyzed people and people with amyotrophic lateral sclerosis (ALS).
2002: The reporting of an ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) study by Jackson Wright, MD, showed that thiazide-type diuretics should be considered first for drug therapy in patients with hypertension.
Actor Christopher Reeve receives a DPS at UH in 2003
In 2004, the Richard M. Ross Heart Hospital opened and became a model for innovative cardiovascular care.
2004: A transformational gift of an initial $25 million from the Goodman family, which continues to grow today through their fund at The Cleveland Foundation, is recognized in naming the Doctor Donald J. and Ruth Weber Goodman Discovery Center for Clinical Research at UH Seidman Cancer Center.
2005: Sanford Markowitz, MD, PhD, discovered a new stool DNA test for colon cancer that became the first commercial test for colon cancer detection.
2008: Mark A. Griswold, PhD, developed parallel imaging technique for magnetic resonance imaging (MRI), which produces clearer, more accurate images in shorter time.
2008: Ronald and Nancy Harrington and their family made a gift of $22.6 million to support the cardiovascular program at UH; in recognition, the program was renamed UH Harrington Heart & Vascular Institute.
The annual Ohio Osteopathic Symposium, a CME conference sponsored collaboratively by OOA and OU-HCOM since 2010, is cancelled due to the rapidly escalating COVID-19 pandemic.
2010: The Program of All-inclusive Care of the Elderly (PACE), one of only two such programs in Ohio, is established.
2011: UH Ahuja Medical Center opened in Beachwood.
2012: The Harrington Discovery Institute was established as a result of a $50 million gift from the Harrington family, the largest gift in UH history to date.
The most advanced cancer hospital in the world, the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, opens in December 2014.
Cleveland Clinic, Ohio University and OU-HCOM announce plans to invest $49.1 million at the South Pointe Hospital campus to renovate a building and hire staff for a regional OU-HCOM campus that will accept 32 students in 2015.
The Cleveland campus opened in 2015 in affiliation with Cleveland Clinic.
2015: Jonathan Miller, MD, was the first in the world to demonstrate that DBS has the potential to improve memory after traumatic brain injury.
The OOA hires a new executive director, Matt Harney, who replaces Jon F. Wills effective February 1, 2018.
The OU-HCOM Class of 2019 is the second largest incoming class of medical students in the state.
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