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In 1968, the Foundation held a capital campaign capped by a generous gift of land from philanthropist Paul D. Perkins, whom he made in honor of his late daughter, Mary Bird.
In 1969, her father, local businessman and philanthropist Paul D. Perkins, made a substantial capstone donation to build Baton Rouge’s first Radiation Treatment Center.
In 1971, the Mary Bird Perkins Radiation Treatment Center opened its doors in Baton Rouge.
In 1974, the first Cancer Control Research Program for the State of Florida was initiated at the cancer center by Doctor Jack Healey.
After 14 years of operation, in 1985, Mary Bird Perkins relocated to its present site on Essen Lane and installed the first linear accelerator in the state.
The following year, in 1986, the name of the center was changed to Mary Bird Perkins Cancer Center.
In 1986, philanthropist Harcourt Sylvester Jr. pledged $27.5 million to benefit cancer programs at the medical school.
After three years of construction, the 117,500 square-foot cancer center opened its doors in June 1992.
Since 1998, Mary Bird Perkins Cancer Center has provided cancer services to the Northshore community.
When the doors of this Cancer Center opened in early 2009, the breadth, scope and quality of services available to cancer patients in Ascension Parish were expanded.
Stephen D. Nimer, M.D., joined the cancer center as director in 2012.
Mary Bird Perkins has been accredited by CAMPEP since 2014.
On July 29, 2019, Sylvester Comprehensive Cancer Center announced it had achieved National Cancer Institute designation, becoming South Florida’s only NCI-designated cancer center.
In 2019, Caring River Cancer Center merged with Mary Bird Perkins Cancer Center to expand its level of care for the Natchez region.
In 2022, Baton Rouge General’s Pennington Cancer Center (BRG) and Mary Bird Perkins Cancer Center partnered to expand and enhance cancer care resources in the Greater Baton Rouge area.
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