Research Fellow jobs at Portia Bell Hume Behavioral Health And Training Center - 331 jobs
Research Associate III - Applied Genomics, Computation & Translational Core (AGCT)
Cedars-Sinai 4.8
Beverly Hills, CA jobs
Research Associate III - Applied Genomics, Computation & Translational Core (AGCT) at CEDARS-SINAI summary:
The Research Associate III at the Applied Genomics, Computation & Translational Core (AGCT) supports advanced genomic research utilizing next-generation sequencing technologies, including single cell omics and spatial transcriptomics. This role involves technical, supervisory, and administrative responsibilities such as sample preparation, data analysis, compliance monitoring, equipment maintenance, and managing lab operations. The position requires a bachelor's degree in a science field, expertise in molecular biology techniques, and strong organizational and communication skills within a healthcare research environment.
Job Description
The Applied Genomics, Computation & Translational Core (AGCT) are looking for a Research Associate III to join the team!
The Cedars-Sinai Applied Genomics, Computation, and Translational Core (AGCT Core) is a fully equipped, state-of-the-art genomics facility offering data generation and interpretation for basic science and translational research in next-generation sequencing technologies, including single cell omics, spatial transcriptomics, and bulk cell omics. We specialize in single cell omics and spatial transcriptomics via the 10x Genomics, Parse Biosciences, Mission Bio, and NanoString platforms. Our R&D team offers sample preparation for single cell assays, such as nuclei isolation from frozen tissue or single cell isolation from fresh tissue dissociation. The AGCT Core also offers comprehensive services for standard bulk cell sequencing in genomics, transcriptomics, epigenomics, and metagenomics. To learn more please visit Applied Genomics, Computation & Translational Core | Cedars-Sinai.
Are you ready to be a part of breakthrough research?
Under general guidance, the Research Associate III works closely with Dr. Gayther, the CBFG and the AGCT Core, providing technical and/or administrative support in large or multi-project oriented labs. May be requested by PI to take on specific supervisory activities, and provide administrative leadership, and/or technical expertise. May develop hypothesis and assist in planning steps for the investigative process. Will review and remain current on literature as it relates to clinical/research study. Coordinates all lab and/or clinical activities, including but not limited to, budgetary/financial compliance, preparation of grant proposals, and creating independent presentations. Not responsible for generating grant funds.
Primary Duties and Responsibilities:
Provides miscellaneous clinical/research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.).
Organizes clinical/research trials in conjunction with the Principal Investigator and sponsor and/or funding source.
Monitors and ensures compliance with safety standards and procedures.
Analyzes data and prepares scientific findings for publication as author or co-author.
May make independent presentations.
May provide system administration and maintenance for the local workstation network.
Leads and trains Research Lab Assistants, ResearchFellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities.
Orients new ResearchFellows and/or Research Scientists to day-to-day lab operations and procedures.
Department-Specific Responsibilities:
May participate as a Safety representative and attend safety monthly meetings providing updates.
Presents quarterly on lab-related protocols, updates, reminders, share information on equipment needed in the lab, discuss lab needs, lab improvements, lab issues, etc.
Assists with BER applications/updates & compliance, conduct safety monitoring with regular lab inspections.
Maintains eyewash weekly activation log, spill kits, safety training and compliance, as well as chemical and biohazard compliance.
Conducts basic training centering of new staff/interns/students/post-doc on proper and safe general lab techniques (e.g. ergonomics, pipette usage, sterile TC techniques, clean-up of spills, etc.).
Oversees CBFG and AGCT Equipment Service/Maintenance Agreements including requesting quotes, submitting requests for PO's, and contacting vendors when an instrument is not working properly, etc.
Liaison for RFO requests including updating contact form and information, as well as reagent quotes.
Serves as the point person for shipments involving dry ice and other biologicals.
Reconciles orders requested and received.
Point of contact for vendors.
Assists farm freezer/ CO2 incubator alarms on Cetani.
Assists with weekly lab ordering and other duties as assigned.
QualificationsEducation:
• Bachelor's Degree in a science related field is required.
Experience & Skills:
Three (3) years of research laboratory experience are required. General understanding of molecular biology.
Familiar with routine laboratory procedures, overall lab organization and cleanliness, as well as proper disposal of waste management.
Must have superior interpersonal, communication and organization skills and the ability to work across company disciplines and functional units, and computer application experience.
Knowledge of safety standards and maintenance of specialized equipment.
About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
Req ID : 12238
Working Title : Research Associate III - Applied Genomics, Computation & Translational Core (AGCT)
Department : Research - BMS - Bioinfo and Func Genomics
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Research Studies/ Clin Trial
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $53,518.40 - $90,979.20
Keywords:
applied genomics, next-generation sequencing, single cell omics, spatial transcriptomics, molecular biology, genomics research, laboratory management, translational research, data analysis, clinical research support
$53.5k-91k yearly 3d ago
Looking for a job?
Let Zippia find it for you.
AI Robotics Research Scientist: Shape Robotic Intelligence
Nimble 3.9
San Francisco, CA jobs
A leading AI robotics firm based in San Francisco is seeking an AI Robotics Research Scientist. This role involves developing and training robotic AI models and working with an all-star team to tackle advanced robotics challenges. The ideal candidate will have a Ph.D. in Robotics or Computer Science and experience in deep learning and robotic hardware. A competitive salary range of $180,000 - $250,000 plus equity is offered, along with strong benefits that include paid time off, health insurance, and 401k contributions.
#J-18808-Ljbffr
$180k-250k yearly 2d ago
AI Robotics Research Scientist
Nimble 3.9
San Francisco, CA jobs
Nimble is an AI robotics company building the autonomous supply chain to enable fast, efficient, and sustainable commerce. We're developing a general-purpose robot AI and a warehouse generalist superhumanoid robot, the first robot in the world capable of performing all core warehouse functions. We recently closed a $106M Series C at a $1B valuation, and we are continuing to grow our world‑class team.
Mission: to empower and inspire mankind to accomplish legendary feats by inventing robots that liberate us from the menial.
Vision: invent the Autonomous Supply Chain - everything from the inside of factories and warehouses to your front door - powered by industry‑generalist superhumanoids to deliver faster, more efficient, and more sustainable commerce.
Our founding team comes from the AI labs at Stanford and Carnegie Mellon and our board of directors include famed robotics and AI legends including Marc Raibert (founder of Boston Dynamics), Sebastian Thrun (founder of GoogleX, Waymo; Stanford Professor and considered the father of autonomous vehicles) and Fei‑Fei Li (Chief Scientist of AI at Google and Director of Stanford's AI Lab).
Join us and leave your mark on the future of robotics, AI, and global commerce.
Why Join Nimble?
At Nimble, we are committed to building legendary products, a legendary team, and a legendary legacy. Join us and become part of an ambitious, humble, and resourceful culture where your work will leave a lasting impact on the future of robotics and commerce.
Nimble's Core Values:
Be relentlessly resourceful - Challenge conventions and overcome obstacles.
Be legendary - Be the very best and do work that inspires.
Be humble - Prioritize growth, learning, and doing whatever is needed to further the mission.
Be dependable - Take ownership and deliver with high agency.
The Role
Nimble is looking for an AI Robotics Research Scientist to help us advance our robotics moonshot by designing, developing, training, and implementing robotic foundation models, Vision‑Language‑Action Models, general‑purpose robotic AI models, and reinforcement learning algorithms controlling multi‑agent robot fleets.
You will play a critical role in working with our all‑star cross‑functional team to build models with immediate applications for the world's biggest robotics opportunity.
Responsibilities
Develop and train diffusion policies, VLMs, multi‑agent deep RL policies and more
Develop data collection pipelines
Design data annotation and labeling
Support implementation of models into production systems
Qualifications
P.h.D in Robotics or Computer Science
Experience training deep learning models for robotic manipulation or mobility
Experience working with real robotic hardware
Experience training models in simulation and developing simulation environments
Experience collecting custom datasets
Experience training on open‑source datasets
Strong track record of publishing papers and/or deploying real‑world applications
Experience with system architecture, design and development
Additional Requirements
Must be able to work extended hours and weekends as needed
Must be able to work in San Francisco
$180,000 - $250,000 a year
The above range is the salary range. This position will also receive generous equity for this position.
Culture
We embrace challenges and strive to make the impossible possible each day. We're not in this to do what's easy or to be mediocre. We want to create something legendary and leave our mark on the world. We're ambitious, we're gritty, we're humble and we're relentlessly resourceful in pursuit of our goals. If this sounds like you then you might be a great fit!
Nimble Robotics, Inc. is an equal opportunity employer. We make all employment decisions based solely on merit. We provide equal employment opportunity to all applicants and employees without discrimination on the basis of race, color, religion, national origin, ancestry, disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, sexual orientation, age, military or veteran status, or any other characteristic protected by applicable state, federal or local laws.
Nimble's Benefits
Paid Time Off
Enjoy the time you need to travel, rejuvenate, and connect with friends and family.
Health Insurance
Nimble provides medical, dental, and vision insurance through several premier plans and options to support you and your family.
Paid Parental Leave
Enjoy paid bonding time following a birth.
Commuter Benefits
Take the stress out of commuting with access to fully-paid parking spots.
Referral Bonus
Get a cash bonus for any friend or colleague that you refer to us that we end up hiring.
401k
Contribute towards a 401k for retirement planning.
Equity
Be an owner in Nimble through our equity program.
#J-18808-Ljbffr
$180k-250k yearly 2d ago
Postdoctoral Scientist - Li Lab - Biomedical Imaging Research Institute
Cedars-Sinai 4.8
Beverly Hills, CA jobs
The Postdoctoral Scientist at the Li Lab conducts advanced MRI research focused on cardiovascular imaging, developing novel techniques for early detection and characterization of heart disease. Working independently and collaboratively, they design experiments, analyze data, and contribute to scientific publications under the mentorship of the Principal Investigator. This role supports breakthrough biomedical imaging research within a leading academic medical center and fosters global scientific collaboration.
Job Description
Join Dr. Debiao Li and their research group as a Postdoctoral Scientist!
The Li Laboratory specializes in the development of novel MRI techniques to address the research and clinical needs of cardiovascular imaging. Our group has developed and optimized various MRI methods for fast imaging of the heart and blood vessels, including coronary artery MR angiography, atherosclerosis imaging, myocardial perfusion and myocardial blood oxygenation evaluation. Our goal is early detection and characterization of heart disease using MRI. We have numerous collaborations with research leaders all over the world, particularly in China, and welcome visiting scientists and students from partner laboratories. Li has mentored more than 50 trainees, including doctorate students, postdocs and researchfellows who have moved on to successful careers in academia, industry and the clinic. The Li Lab is a key partner of Siemens Healthineers, and scientists from Siemens are working with us on-site to develop and apply novel MRI techniques. To learn more, please visit Li Lab | Cedars-Sinai.
Are you ready to be a part of breakthrough research?
Working independently but in close cooperation and in consultation with the Principal Investigator and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. May assist in preparation of grant proposals. Participates in publications and presentations as author or co-author. Not responsible for generating grant funds.
Primary Job Duties and Responsibilities:
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
May participate in publications and presentations as author or co-author.
Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator.
May develop, adapt, and implement new research techniques and protocols.
Analyzes, interprets, summarizes, and compiles data.
Operates and maintains equipment and instruments.
May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.
Qualifications
Education:
• Doctorate (MD, PhD, VMD, or DDS) in an area directly related to the field of research specialization.
Experience and Skills:
Acquires thorough technical and theoretical knowledge of research project and objectives during one to fiveyear post-doctoral appointment. Understanding of general research objectives.
Works independently on research projects designed by a mentor (typically the PI) within the area of specialization.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment.
About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
Req ID : 12017
Working Title : Postdoctoral Scientist - Li Lab - Biomedical Imaging Research Institute
Department : BMS - BioMed Imaging Res Inst.
Business Entity : Cedars-Sinai Medical Center
Job Category : Academic / Research
Job Specialty : Postdoctoral Scholar
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour
Base Pay : $62,400 - $93,600
Keywords:
postdoctoral scientist, MRI techniques, cardiovascular imaging, biomedical research, heart disease detection, magnetic resonance imaging, clinical research, data analysis, scientific publications, academic medical center
$62.4k-93.6k yearly 5d ago
Foundational AI Speech Scientist, STT/TTS Research, Equity
Aldea Inc. 3.9
San Francisco, CA jobs
A pioneering AI technology company in San Francisco seeks a Foundational AI Research Scientist (Speech) to advance speech understanding and generation. The role involves leading research in STT, TTS, and speech-to-speech modeling, requiring a Ph.D. and substantial experience in training foundational models. Candidates should possess deep expertise in modern sequence modeling architectures and a history of impactful research contributions. The company offers flexible paid time off and comprehensive health coverage.
#J-18808-Ljbffr
$61k-94k yearly est. 5d ago
Foundational LLM Research Scientist - Scaling & Efficiency
Aldea Inc. 3.9
San Francisco, CA jobs
A multi-modal foundational AI company is seeking a Foundational AI Research Scientist to lead research on large-language-model architectures. The role involves designing and validating new transformer variants and attention mechanisms for production systems. Ideal candidates will have a Ph.D. and 3+ years of industry experience in AI research, with deep knowledge of sequence modeling architectures and pre-training of large models. The position offers a competitive salary, flexible PTO, and comprehensive benefits.
#J-18808-Ljbffr
$61k-94k yearly est. 5d ago
Foundational AI Speech Scientist, STT/TTS Research, Equity
Aldea Inc. 3.9
San Francisco, CA jobs
A pioneering AI company based in San Francisco seeks a Foundational AI Research Scientist (Speech) to drive advancements in speech understanding and generation. This role requires a Ph.D. and extensive experience in TTS and STT systems. Responsibilities include prototyping architectures, executing validation experiments, and collaborating with engineering teams. The ideal candidate will have deep expertise in modern sequence modeling and a proven track record with large-scale datasets. A strong engineering intuition and the ability to translate complex ideas into maintainable code are essential.
#J-18808-Ljbffr
$61k-94k yearly est. 4d ago
Senior Oncology Bioinformatics Scientist
Gilead Sciences, Inc. 4.5
Foster City, CA jobs
A leading biotech company in Foster City is searching for a Senior Scientist with extensive experience in analyzing omics data such as RNA-Seq and WES. The ideal candidate will have a PhD and 8+ years of experience in the pharmaceutical or biotech industry, strong statistics knowledge, and excellent communication skills. Responsibilities include synthesizing scientific questions into research efforts and empowering teams to achieve organizational objectives. Join a dynamic team that values diversity and supports professional growth.
#J-18808-Ljbffr
$88k-133k yearly est. 4d ago
Scientist
Aequor 3.2
Pleasanton, CA jobs
Job Title: Scientist II
Duration: Until 01/26/2027
Required Skills
Bachelor's degree in Molecular Biology, Cellular Biology, Microbiology, or a related field with 5+ years of relevant experience, or
Master's degree in Molecular Biology, Cellular Biology, Microbiology, or a related field with 3+ years of relevant experience
Experience with Aseptic techniques and Bacterial and/or Mammalian cell culture.
Experience with Cloning techniques, including Plasmid design and preparation, restriction enzyme digestion, ligation, bacterial transformation, and Downstream processing.
Experience performing Nucleic Acid Extractions (DNA/RNA), quantification, amplification
Experience with LIMS software, electronic lab notebooks (eLN), and JMP is preferred
$106k-167k yearly est. 4d ago
Foundational AI Scientist (LLMs)
Aldea Inc. 3.9
San Francisco, CA jobs
An innovative AI startup in San Francisco is looking for a Foundational AI Research Scientist to pioneer next-generation large-language-model architectures. Ideal candidates will have a deep understanding of sequence modeling architectures, expertise in PyTorch, and experience in pre-training large language models. Join a dynamic team to help shape the future of intelligent human-machine interfaces.
#J-18808-Ljbffr
$48k-73k yearly est. 1d ago
High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Amber Bio 4.2
San Jose, CA jobs
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
$62k-79k yearly est. 11h ago
High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Amber Bio 4.2
Santa Rosa, CA jobs
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
$62k-79k yearly est. 11h ago
High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Amber Bio 4.2
San Francisco, CA jobs
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
$62k-79k yearly est. 11h ago
High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Amber Bio 4.2
Fremont, CA jobs
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
$62k-79k yearly est. 11h ago
Sr. Bioinformatics Scientist (Assay Development Analytics)
Karius 4.2
Redwood City, CA jobs
Karius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions.
Why Should You Join Us?
Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease.
Position Summary
You are highly curious and creative and desire to continuously grow and improve in your goal to make an impact on patients. You will be a key member of the Assay Development Analytics (ADA) team that helps drive the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. You will participate in experimental design, conduct thoughtful computational analyses by determining the analysis plan and executing it using the necessary tools and methodologies. You will work closely with colleagues in Molecular Biology to understand and deliver on our shared goals. You are a self-starter and always like to find ways to make things better.
Reports to: Sr. Manager, Bioinformatics
Location: Redwood City, CA or hybrid or remote
Primary Responsibilities
* Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques.
* Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays.
* Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies.
* Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature.
* Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines.
* Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.
* Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.
* Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.
* Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor.
What's Fun About the Job?
Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: Travel to HQ on a quarterly basis if remote.
Physical Requirements
Subject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment.
Position Requirements
* Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.
* Publications demonstrating innovative investigation and interpretation of biological data.
* Proven proficiency, and understanding of, modern statistics and machine learning.
* Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.
* Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.
* Self-starter with the ability to independently drive results and influence project direction.
* Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.
* Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues).
* Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis.
* Familiarity with design of experiments (DOE) approaches to optimize process settings.
Personal Qualifications
* Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.
* Excellence at communication and collaboration within a cross-functional team.
* Detail oriented with exceptional organizational and time management skills.
* Self-starting mentality and ability to drive results.
* Comfortable working in an environment which combines both research aspects as well as development.
* Ability to work effectively and efficiently in a fast-paced (startup) environment.
Disclaimer
The above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.
Equal Opportunity Employer
At Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities.
$142,231 - $213,347 a year
$142.2k-213.3k yearly 60d+ ago
Senior Bioinformatics Scientist
Karius 4.2
Redwood City, CA jobs
About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions.
Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease.
Position SummaryYou are highly curious, creative, and driven by a desire for continuous growth with the ultimate goal of making a meaningful impact on patients' lives. As a key and integral member of the Computational Biomarker Discovery team, you will focus on deeply exploring and analyzing the complex biological interplay between diverse conditions and molecular data. In this role, you will help unlock and help unlock preliminary biological signatures to inform translational science and precision medicine beyond the conventional infectious disease arena, and into areas such as autoimmune and cancer. You will design analysis plans, execute computational workflows, partner for method and machine learning model development, and integrate biological rationale with data-driven insights to uncover meaningful connections. You bring a passion for applying technology in novel ways, generating innovative hypotheses, and revealing hidden patterns in data. Your curiosity and analytical rigor will drive discoveries that push the boundaries of biomarker research and patient care.
Reports to: Director, Computational Biomarker Discovery
Location: Redwood City, CA (Hybrid) or Remote (USA)
Primary Responsibilities• Lead data analysis and interpretation of complex biological datasets, including next-generation sequencing (NGS), metagenomics, transcriptomics, fragmentomics, and single-cell analysis.• Create or adapt computational tools and algorithms to support biomarker discovery and workflows.• Drive bioinformatics aspects of cross-functional research projects in collaboration with scientific and medical leaders, under the guidance of the Director of Computational Biomarker Discovery.• Conduct deep exploration of the biological interplay between molecular data and disease conditions, generating insights to advance translational science.• Deliver preliminary biological signatures that inform precision medicine applications beyond infectious disease, including autoimmune disorders and oncology.• Partner in experimental design by defining analysis plans, selecting appropriate methodologies, and executing computational analyses with a strong grounding in biological rationale.• Collaborate closely with scientific, medical, engineering, and commercial teams to set company goals and support the development of new partnerships and products.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share enthusiasm for exploring novel applications of Karius' technology platform to drive innovation and impact.
What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: Travel to HQ on a quarterly basis if remote.
Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment.
Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating the use of innovative mathematical or computational models to investigate and interpret biological and biomarker data.• Strong background in modern statistics and machine learning, including applications to biomarker discovery.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Deep understanding and hands-on experience with bioinformatics tools, methods, and workflows, especially those related to next-generation sequencing (NGS) data analysis.• Familiarity with exploratory study and clinical trial designs and analyses, particularly in pharmaceutical or biotechnology applications.
Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment.
DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.
Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities.
$142,231 - $213,347 a year
$142.2k-213.3k yearly Auto-Apply 60d+ ago
Sr. Bioinformatics Scientist (Assay Development Analytics)
Karius 4.2
Redwood City, CA jobs
About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions.
Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease.
Position SummaryYou are highly curious and creative and desire to continuously grow and improve in your goal to make an impact on patients. You will be a key member of the Assay Development Analytics (ADA) team that helps drive the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. You will participate in experimental design, conduct thoughtful computational analyses by determining the analysis plan and executing it using the necessary tools and methodologies. You will work closely with colleagues in Molecular Biology to understand and deliver on our shared goals. You are a self-starter and always like to find ways to make things better.
Reports to: Sr. Manager, Bioinformatics
Location: Redwood City, CA or hybrid or remote
Primary Responsibilities• Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques.• Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays.• Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies.• Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature.• Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor.
What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters.
Travel: Travel to HQ on a quarterly basis if remote.
Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment.
Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating innovative investigation and interpretation of biological data. • Proven proficiency, and understanding of, modern statistics and machine learning.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues).• Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis.• Familiarity with design of experiments (DOE) approaches to optimize process settings.
Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment.
DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.
Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities.
$142,231 - $213,347 a year
$142.2k-213.3k yearly Auto-Apply 60d+ ago
Senior Bioinformatics Scientist
Billiontoone 4.1
Menlo Park, CA jobs
Ready to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary-a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion-every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.
We are looking for a Senior Bioinformatics Scientist to join a fast growing team. This person will be responsible for the generation, analysis, and communication of clinical next-generation DNA sequencing data for the Northstar oncology products. Our sample volume is growing extremely quickly, and this role will own the further development of our analysis pipeline to analyze tens of thousands of samples, and be the lead scientist for everything related to our bioinformatics analyses. The Senior Bioinformatics Scientist role is a full-time onsite position and reports to the Senior Manager of Bioinformatics, Oncology.
Responsibilities:
Develop sophisticated and robust NGS analysis pipelines capable of processing tens of thousands of samples
Develop tests and test frameworks for NGS pipelines
Analyze and troubleshoot clinical NGS data
Analyze assay performance and contribute to publications that demonstrate the clinical validity and utility of our tests
Design new quality metrics and processes for clinical molecular diagnostic assays
Collaborate with R&D scientists to generate new scientific insights
Communicate assay performance and capabilities to clinical personnel at weekly meetings and to other non-clinical stakeholders
Qualifications:
PhD in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related fields
2+ years of experience developing robust and scalable bioinformatics pipelines
2+ years of experience analyzing NGS data
Fluency in Python
Experience with Linux environment, GitHub and AWS
Excellent communication and presentation skills, ability to work across functional teams and with non-experts
Nice-To-Haves:
Start-up experience
Experience working in a regulated environment
Experience with CI/CD pipelines and dockerized code deployment
Experience with cloud infrastructure management with infrastructure as code such as CDK
Benefits And Perks:
Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
Open, transparent culture that includes weekly Town Hall meetings
The ability to indirectly or directly change the lives of hundreds of thousands patients
Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
Supplemental fertility benefits coverage
Retirement savings program including a 4% Company match
Increase paid time off with increased tenure
Latest and greatest hardware (laptop, lab equipment, facilities)
Daily on-site lunches provided from top eateries
A variety of perks on campus (state of the art gym, restaurant)
Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $244,805 per year, including a base pay range of $156,060 - $176,868 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
For more information about how we protect your information, we encourage you to review our Privacy Policy.
About BillionToOne
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA-a breakthrough that's already transformed the lives of over half a million patients worldwide.
Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024-with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated-one that remains authentically collaborative and transparent even as we've scaled.
Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started.
At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work.
Ready to help us change the world, one diagnosis at a time?
Learn more at ********************
$156.1k-176.9k yearly Auto-Apply 8d ago
Senior Bioinformatics Scientist
Invivoscribe Inc. 4.2
San Diego, CA jobs
Job Description
Invivoscribe is an industry pioneer, dedicated to Improving Lives with Precision Diagnostics . Invivoscribe has been the global leader in driving international standardization of testing and accelerating patient access to the newest and best cancer treatments for over 30 years.
Headquartered in sunny San Diego, California with locations across the world, we offer a comprehensive portfolio of products and services. We work with key collaborators to develop molecular assays, reagents, controls and bioinformatics tools under ISO 13485 design control that are used by over 700 clinical laboratories in over 160 countries.
Our global network of laboratories offers internationally standardized next generation molecular and flow cytometry panels to support drug development and accelerate drug approvals worldwide. We work with pharmaceutical partners and international regulatory agencies across the globe to develop companion diagnostics, which are necessary to gain approval of new drugs and treatments for cancer patients. Our harmonized ISO15189 accredited and CLIA/CAP clinical laboratories offer a test menu focused on biomarkers which are clinically actionable to support therapeutic decisions, measurable residual disease (MRD) testing, patient stratification, and trial enrollment, all designed to accelerate approvals of new oncology drugs and treatments.
For 30 years, we have been at forefront of precision diagnostics, and we're just getting started!
We are looking to add a Senior Bioinformatics Scientist. The Senior Bioinformatics Scientist is a hands-on technical leader with advanced knowledge of scientific principles and concepts who designs, builds, and validates production-grade bioinformatics software and scalable NGS pipelines (on-prem and cloud) to diagnose and track disease (MRD) for clinical and research applications. This role independently identifies opportunities, defines technical roadmaps, and leads delivery from requirements and design through implementation, verification/validation, release, and lifecycle support.
Core Responsibilities Include:
Lead the design and development of bioinformatics software and pipelines to support Whole Genome Sequencing (WGS), hybrid-capture, and amplicon based NGS assays.
Work in close collaboration with the R&D and clinical lab teams, representing bioinformatics from a technical leadership role.
Evaluate and develop novel methods and external tools; perform benchmarking and method comparisons, and document recommendations and decisions; own projects end-to-end.
Develop reproducible, testable bioinformatics software using modern engineering practices (git, code review, unit/integration tests, CI/CD, containerization), and workflow technologies (e.g., Nextflow).
Apply deep Next Generation Sequencing (NGS) analytics expertise and partner with scientific stakeholders to translate bioinformatics outputs into actionable conclusions.
Lead bioinformatics software development for CAP/CLIA/NYA environments, including requirements definition, design documentation, verification and validation planning/execution, traceability, change control, and release documentation.
Provide technical leadership across cross-functional teams and influence others to raise team standards (R&D, clinical labs, QA/RA, DevOps).
You Bring:
Ph.D. degree in bioinformatics, computational biology, molecular biology, or related field with, typically, 8+ years applicable post-graduate experience. M.S. degree in bioinformatics or related field and 10+ years of applicable post-graduate experience. Equivalent combination of education and experience may be considered.
Advanced proficiency with Linux and strong programming skills (Python, bash required; additional languages welcome).
Experience building and/or leveraging AI agents and LLMs for various tasks and optimization of software development.
Demonstrated experience designing and building production bioinformatics pipelines for WGS/WTS assays.
Hands-on experience developing and operating bioinformatics software in the cloud, including workflow execution at scale and management of compute/storage costs.
Experience collaborating across multi-disciplinary teams and providing technical leadership through influence (with or without direct reports).
Strong foundation in statistics and quantitative analysis of biological datasets.
Extensive background in immunology or cancer research is highly preferred.
Experience developing software in a regulated environment is a plus (e.g. IVD, IVDR, CAP/CLIA/NYS).
Proficient computer skills and good working knowledge of Microsoft Office programs and collaboration tools (Word, Outlook, Teams, Excel and PowerPoint) and the ability to learn new software programs.
We Bring:
A beautiful modern facility centrally located in San Diego County, with many jobs conducive to flexible scheduling and telework options.
A welcoming breakroom for gathering with hosted hot/cold beverages and healthy convenience foods, and an available micro-market to get you through the day.
A positive workplace culture with an emphasis on support, respect and belonging.
A diverse and inclusive work environment where you will learn, grow, and make new friends.
Competitive pay, discretionary bonus program, incentive stock options, generous benefit options, 401k with a fully vested employer match, and generous time off benefits.
Invivoscribe is an Equal Opportunity Employer.
$86k-134k yearly est. 4d ago
Senior Bioinformatics Scientist
Invivoscribe Inc. 4.2
San Diego, CA jobs
Invivoscribe is an industry pioneer, dedicated to Improving Lives with Precision Diagnostics . Invivoscribe has been the global leader in driving international standardization of testing and accelerating patient access to the newest and best cancer treatments for over 30 years.
Headquartered in sunny San Diego, California with locations across the world, we offer a comprehensive portfolio of products and services. We work with key collaborators to develop molecular assays, reagents, controls and bioinformatics tools under ISO 13485 design control that are used by over 700 clinical laboratories in over 160 countries.
Our global network of laboratories offers internationally standardized next generation molecular and flow cytometry panels to support drug development and accelerate drug approvals worldwide. We work with pharmaceutical partners and international regulatory agencies across the globe to develop companion diagnostics, which are necessary to gain approval of new drugs and treatments for cancer patients. Our harmonized ISO15189 accredited and CLIA/CAP clinical laboratories offer a test menu focused on biomarkers which are clinically actionable to support therapeutic decisions, measurable residual disease (MRD) testing, patient stratification, and trial enrollment, all designed to accelerate approvals of new oncology drugs and treatments.
For 30 years, we have been at forefront of precision diagnostics, and we're just getting started!
We are looking to add a Senior Bioinformatics Scientist. The Senior Bioinformatics Scientist is a hands-on technical leader with advanced knowledge of scientific principles and concepts who designs, builds, and validates production-grade bioinformatics software and scalable NGS pipelines (on-prem and cloud) to diagnose and track disease (MRD) for clinical and research applications. This role independently identifies opportunities, defines technical roadmaps, and leads delivery from requirements and design through implementation, verification/validation, release, and lifecycle support.
Core Responsibilities Include:
Lead the design and development of bioinformatics software and pipelines to support Whole Genome Sequencing (WGS), hybrid-capture, and amplicon based NGS assays.
Work in close collaboration with the R&D and clinical lab teams, representing bioinformatics from a technical leadership role.
Evaluate and develop novel methods and external tools; perform benchmarking and method comparisons, and document recommendations and decisions; own projects end-to-end.
Develop reproducible, testable bioinformatics software using modern engineering practices (git, code review, unit/integration tests, CI/CD, containerization), and workflow technologies (e.g., Nextflow).
Apply deep Next Generation Sequencing (NGS) analytics expertise and partner with scientific stakeholders to translate bioinformatics outputs into actionable conclusions.
Lead bioinformatics software development for CAP/CLIA/NYA environments, including requirements definition, design documentation, verification and validation planning/execution, traceability, change control, and release documentation.
Provide technical leadership across cross-functional teams and influence others to raise team standards (R&D, clinical labs, QA/RA, DevOps).
You Bring:
Ph.D. degree in bioinformatics, computational biology, molecular biology, or related field with, typically, 8+ years applicable post-graduate experience. M.S. degree in bioinformatics or related field and 10+ years of applicable post-graduate experience. Equivalent combination of education and experience may be considered.
Advanced proficiency with Linux and strong programming skills (Python, bash required; additional languages welcome).
Experience building and/or leveraging AI agents and LLMs for various tasks and optimization of software development.
Demonstrated experience designing and building production bioinformatics pipelines for WGS/WTS assays.
Hands-on experience developing and operating bioinformatics software in the cloud, including workflow execution at scale and management of compute/storage costs.
Experience collaborating across multi-disciplinary teams and providing technical leadership through influence (with or without direct reports).
Strong foundation in statistics and quantitative analysis of biological datasets.
Extensive background in immunology or cancer research is highly preferred.
Experience developing software in a regulated environment is a plus (e.g. IVD, IVDR, CAP/CLIA/NYS).
Proficient computer skills and good working knowledge of Microsoft Office programs and collaboration tools (Word, Outlook, Teams, Excel and PowerPoint) and the ability to learn new software programs.
We Bring:
A beautiful modern facility centrally located in San Diego County, with many jobs conducive to flexible scheduling and telework options.
A welcoming breakroom for gathering with hosted hot/cold beverages and healthy convenience foods, and an available micro-market to get you through the day.
A positive workplace culture with an emphasis on support, respect and belonging.
A diverse and inclusive work environment where you will learn, grow, and make new friends.
Competitive pay, discretionary bonus program, incentive stock options, generous benefit options, 401k with a fully vested employer match, and generous time off benefits.
Invivoscribe is an Equal Opportunity Employer.
$86k-134k yearly est. Auto-Apply 2d ago
Learn more about Portia Bell Hume Behavioral Health And Training Center jobs